Ddx5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000048490 0.04 0.02 4.6e-04 0.04 0.03 0.03 0.03 4.8e-05 2.2e-04 2.1e-04 1.3e-04
2 Adipose alternative polyA ENSRNOT00000098583 0.04 0.02 4.7e-04 0.03 0.03 0.03 0.03 1.8e-04 2.2e-04 2.5e-04 1.7e-04
3 Adipose alternative polyA ENSRNOT00000048490 0.04 0.02 1.6e-04 0.04 0.04 0.04 0.04 1.5e-05 5.3e-05 6.5e-05 3.3e-05
4 Adipose alternative polyA ENSRNOT00000098583 0.04 0.03 1.8e-04 0.04 0.04 0.04 0.04 2.6e-05 6.2e-05 8.7e-05 6.3e-05
5 Adipose isoform ratio ENSRNOT00000048490 0.07 0.04 4.7e-05 0.04 0.05 0.04 0.04 2.0e-05 1.6e-06 1.1e-05 1.1e-05
6 Adipose isoform ratio ENSRNOT00000098583 0.07 0.05 1.3e-04 0.04 0.04 0.03 0.04 2.3e-05 1.7e-05 1.4e-04 3.4e-05
7 Adipose mRNA stability ENSRNOG00000030680 0.05 0.02 1.0e-06 0.06 0.06 0.06 0.06 4.0e-07 4.1e-07 2.1e-07 2.8e-07
8 Brain alternative polyA ENSRNOT00000048490 0.05 0.03 8.1e-06 0.05 0.05 0.04 0.05 1.2e-05 2.8e-05 1.8e-04 2.7e-05
9 Brain alternative polyA ENSRNOT00000098583 0.06 0.03 3.1e-06 0.06 0.05 0.04 0.05 5.7e-06 9.3e-06 1.4e-04 1.2e-05
10 Brain alternative polyA ENSRNOT00000048490 0.06 0.03 4.9e-06 0.06 0.05 0.04 0.06 6.5e-06 1.9e-05 1.1e-04 7.0e-06
11 Brain alternative polyA ENSRNOT00000098583 0.06 0.03 1.5e-06 0.06 0.06 0.04 0.06 2.0e-06 5.8e-06 6.3e-05 5.8e-06
12 Brain isoform ratio ENSRNOT00000048490 0.04 0.02 2.0e-04 0.03 0.04 0.03 0.04 4.2e-04 1.0e-04 3.5e-04 9.8e-05
13 Brain isoform ratio ENSRNOT00000098583 0.05 0.03 2.2e-05 0.07 0.05 0.05 0.06 8.5e-07 1.8e-05 2.1e-05 3.0e-06
14 IL isoform ratio ENSRNOT00000048490 0.19 0.11 3.2e-03 0.08 0.07 0.06 0.1 4.8e-03 9.1e-03 1.3e-02 2.4e-03
15 Liver alternative polyA ENSRNOT00000098583 0.03 0.03 7.4e-03 0.02 0.01 0.03 0.02 2.9e-03 1.9e-02 6.0e-04 3.2e-03
16 Liver alternative polyA ENSRNOT00000098583 0.04 0.03 9.6e-03 0.01 0.01 0.02 0.01 7.9e-03 5.1e-02 2.6e-03 1.9e-02
17 Liver isoform ratio ENSRNOT00000048490 0.03 0.02 8.0e-03 0.02 0 0.01 0.01 6.2e-03 9.1e-02 3.3e-02 4.4e-02
18 NAcc alternative polyA ENSRNOT00000048490 0.06 0.05 1.6e-03 0.03 0.03 0.02 0.03 1.3e-03 1.9e-03 9.4e-03 2.2e-03
19 NAcc alternative polyA ENSRNOT00000098583 0.06 0.05 6.6e-04 0.04 0.04 0.02 0.04 5.3e-04 1.0e-03 1.0e-02 7.8e-04
20 NAcc alternative polyA ENSRNOT00000048490 0.06 0.05 2.3e-03 0.04 0.03 0.02 0.03 1.2e-03 1.4e-03 1.6e-02 2.3e-03
21 NAcc alternative polyA ENSRNOT00000098583 0.08 0.08 1.1e-03 0.04 0.04 0.02 0.03 7.7e-04 8.9e-04 1.1e-02 1.6e-03
22 NAcc mRNA stability ENSRNOG00000030680 0.05 0.03 2.3e-03 0.03 0.02 0.01 0.01 2.7e-03 1.9e-02 1.0e-01 4.0e-02
23 PL alternative polyA ENSRNOT00000048490 0.09 0.05 1.3e-04 0.03 0.03 0.04 0.04 3.8e-03 1.9e-03 1.1e-03 7.8e-04
24 PL alternative polyA ENSRNOT00000098583 0.07 0.04 1.6e-04 0.04 0.04 0.04 0.04 4.6e-04 7.4e-04 5.1e-04 4.7e-04
25 PL alternative polyA ENSRNOT00000048490 0.07 0.04 6.1e-04 0.03 0.02 0.03 0.03 1.8e-03 6.9e-03 1.3e-03 1.5e-03
26 PL alternative polyA ENSRNOT00000098583 0.06 0.04 5.5e-04 0.04 0.03 0.02 0.04 5.5e-04 1.3e-03 1.4e-02 7.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
BMI with tail0.41.25.20.10.30.1-0.1-2.32.2-0.90.2-0.90.9-0.90.50.01.22.02.3-1.4-0.20.2-0.20.2-1.1-0.90.6-0.7-0.8
BMI without tail1.12.27.51.2-1.01.2-1.2-1.81.50.21.6-2.42.4-2.41.7-1.12.71.41.8-0.01.3-1.31.1-1.1-0.10.6-0.80.7-2.0
Body weight1.67.013.83.0-2.83.0-3.0-0.0-0.51.82.9-3.73.7-3.73.5-2.43.6-0.00.21.02.7-2.73.1-3.11.12.4-1.62.3-3.6
Epididymis fat weight0.92.15.41.2-1.01.2-1.2-1.30.51.61.1-2.02.0-2.01.7-1.22.3-1.0-0.81.21.3-1.31.1-1.11.21.2-2.01.6-2.0
Glucose0.81.22.3-1.01.0-1.01.0-0.10.4-1.1-1.51.2-1.21.2-1.31.1-1.40.80.7-0.8-0.90.9-1.31.3-1.5-1.00.9-1.01.3
Heart weight0.40.52.1-0.80.8-0.80.8-1.01.2-0.90.00.4-0.40.4-0.50.2-0.41.41.4-1.1-0.50.5-0.30.3-0.30.10.9-0.00.6
Left kidney weight1.02.910.2-1.11.1-1.11.1-0.91.5-2.6-0.90.9-0.90.9-1.01.4-1.13.23.2-2.9-1.41.4-0.80.8-2.3-1.22.9-1.61.1
Right kidney weight0.41.34.9-0.60.6-0.60.6-0.30.7-1.9-0.20.5-0.50.5-0.31.0-0.62.22.2-2.2-1.11.10.2-0.2-1.5-0.62.2-0.90.7
Tail length1.95.78.32.3-2.42.3-2.30.6-1.22.32.4-2.82.8-2.82.7-2.32.9-1.1-1.12.22.8-2.82.8-2.81.82.6-2.52.5-2.6
Length with tail2.17.712.02.9-3.02.9-2.91.8-2.42.82.7-3.03.0-3.03.3-2.22.6-1.8-1.92.32.9-2.93.4-3.42.13.5-2.43.1-3.0
Length without tail0.61.42.91.2-1.21.2-1.21.4-1.71.40.7-0.80.8-0.81.3-0.70.4-1.4-1.61.00.8-0.81.5-1.51.01.6-0.91.4-1.0
Liver weight, left0.91.43.01.2-1.21.2-1.21.1-1.31.10.8-1.11.1-1.11.3-0.90.6-0.9-1.01.01.4-1.41.5-1.50.71.7-1.01.5-1.2
Liver weight, right0.20.32.5-0.30.5-0.30.3-0.70.4-0.8-0.1-0.10.1-0.1-0.01.6-0.40.70.7-0.9-0.90.9-0.30.3-0.30.50.40.4-0.2
Parametrial fat weight1.02.04.11.1-0.91.1-1.1-0.0-0.81.61.0-1.41.4-1.41.7-0.41.4-1.8-1.81.30.7-0.71.8-1.81.81.9-1.82.0-1.5
Retroperitoneal fat weight2.16.911.52.9-2.82.9-2.90.9-1.72.52.6-3.23.2-3.23.1-2.33.4-1.9-1.72.22.6-2.62.9-2.92.22.0-2.42.3-3.1
Intraocular pressure0.40.63.8-0.20.2-0.20.2-1.91.8-0.2-0.5-0.60.6-0.60.3-0.71.21.01.2-0.40.4-0.40.1-0.1-1.0-0.1-0.2-0.1-0.2
Extensor digitorum longus weight1.04.214.9-2.42.7-2.42.4-3.93.4-0.9-1.41.8-1.81.8-2.21.5-1.00.30.5-0.5-2.22.2-3.13.10.0-2.0-0.3-1.31.6
Soleus weight0.10.31.5-0.00.1-0.00.0-0.30.6-0.50.1-0.00.0-0.00.2-0.70.01.21.2-0.70.4-0.40.7-0.7-0.80.00.7-0.30.0
Tibialis anterior weight0.20.53.00.4-0.00.4-0.4-1.71.40.80.4-0.60.6-0.60.6-0.91.2-0.4-0.10.80.6-0.60.1-0.10.4-0.3-1.20.0-0.8
Tibia length0.20.53.1-0.30.3-0.30.3-0.20.3-1.20.1-0.10.1-0.10.10.7-0.21.71.7-1.1-0.20.20.7-0.7-0.90.61.00.10.2
Number of licking bursts0.00.00.30.0-0.10.0-0.00.5-0.4-0.0-0.20.2-0.20.2-0.10.0-0.40.0-0.00.10.0-0.00.0-0.0-0.20.30.00.10.1
Food consumed during 24 hour testing period2.32.85.51.7-1.61.7-1.7-0.2-0.21.61.3-2.12.1-2.12.1-2.02.3-0.6-0.51.42.1-2.12.0-2.00.61.2-1.71.3-2.0
Times rat made contact with spout0.91.02.01.0-1.01.0-1.00.7-0.90.90.6-1.01.0-1.01.1-0.91.1-0.7-0.71.21.4-1.41.3-1.30.50.8-1.10.8-0.9
Mean time between licks in bursts0.10.20.60.3-0.10.3-0.3-0.50.20.40.2-0.60.6-0.60.4-0.00.3-0.2-0.20.30.1-0.1-0.00.00.30.8-0.50.8-0.5
Mean num. licks in bursts0.20.31.10.3-0.20.3-0.3-0.80.50.40.4-0.70.7-0.70.6-0.51.1-0.2-0.10.40.6-0.60.5-0.50.40.1-0.70.3-0.6
Std. dev. time between licks in bursts0.10.10.4-0.10.2-0.10.1-0.70.50.1-0.4-0.10.1-0.1-0.10.20.2-0.00.10.1-0.10.1-0.40.4-0.3-0.2-0.2-0.2-0.1
Water consumed over 24 hours0.20.20.60.5-0.40.5-0.5-0.20.10.00.5-0.70.7-0.70.6-0.00.80.30.50.00.5-0.50.6-0.6-0.00.1-0.20.1-0.7
Indifference point 0 sec3.76.012.22.6-2.52.6-2.60.2-0.61.93.5-3.23.2-3.22.9-2.83.1-0.3-0.11.12.6-2.62.6-2.62.22.6-1.42.5-2.9
Indifference point AUC1.82.14.51.6-1.51.6-1.60.4-0.71.41.5-1.71.7-1.71.6-1.21.5-0.7-0.61.42.1-2.11.1-1.10.91.4-1.71.4-1.8
Indifference point function ln k0.91.23.9-0.90.9-0.90.9-0.60.9-1.4-0.11.0-1.01.0-0.90.9-0.91.51.4-1.9-1.71.7-0.50.5-0.5-0.82.0-0.91.1
Indifference point function log k0.91.23.9-0.90.9-0.90.9-0.60.9-1.4-0.11.0-1.01.0-0.90.9-0.91.51.4-1.9-1.71.7-0.50.5-0.5-0.82.0-0.91.1
Delay discounting total patch changes 0 sec3.96.212.02.7-2.62.7-2.70.2-0.72.03.5-3.23.2-3.22.9-2.93.1-0.4-0.31.32.6-2.62.7-2.72.32.8-1.52.6-2.9
Delay discounting total patch changes 12 sec5.97.810.82.9-2.92.9-2.91.0-1.52.93.1-3.33.3-3.33.0-3.23.0-1.6-1.52.33.3-3.32.6-2.62.63.2-2.63.1-3.1
Delay discounting total patch changes 18 sec2.73.67.02.1-2.22.1-2.10.8-1.01.71.9-2.42.4-2.42.1-2.52.3-0.6-0.51.22.6-2.61.8-1.81.11.5-1.31.5-2.2
Delay discounting total patch changes 24 sec3.74.68.22.2-2.02.2-2.20.2-0.51.62.9-2.82.8-2.82.5-2.32.5-0.00.11.12.7-2.72.3-2.31.72.5-1.52.3-2.6
Delay discounting total patch changes 6 sec3.04.67.82.5-2.42.5-2.50.8-1.21.82.8-2.72.7-2.72.5-2.12.4-0.6-0.51.32.4-2.42.0-2.01.82.1-1.62.0-2.7
Delay discounting time to switch 0 sec0.30.42.2-0.60.5-0.60.60.3-0.2-0.1-1.50.8-0.80.8-0.70.2-0.6-0.4-0.50.0-0.60.6-0.40.4-0.9-1.10.2-0.90.8
Delay discounting water rate 0 sec1.72.76.81.8-1.71.8-1.8-0.1-0.31.12.6-2.22.2-2.22.0-1.42.3-0.3-0.10.71.4-1.41.7-1.71.81.6-1.11.6-2.1
Delay discounting water rate 12 sec0.81.23.4-0.80.9-0.80.8-0.50.7-1.7-0.20.7-0.70.7-0.81.7-0.91.61.6-1.8-1.61.6-0.90.9-0.7-0.91.7-0.90.7
Delay discounting water rate 18 sec0.40.52.5-0.20.2-0.20.2-0.10.2-1.00.50.1-0.10.10.10.4-0.41.21.2-1.6-1.21.20.4-0.4-0.20.11.5-0.10.1
Delay discounting water rate 24 sec0.20.21.1-0.30.2-0.30.30.1-0.0-0.6-0.40.3-0.30.3-0.10.1-0.40.50.5-1.0-1.01.00.3-0.3-0.40.11.0-0.10.4
Delay discounting water rate 6 sec0.30.51.8-0.50.5-0.50.5-0.90.9-0.9-0.00.2-0.20.2-0.20.7-0.11.11.1-1.3-1.01.0-0.10.1-0.4-0.11.0-0.30.3
Locomotor activity0.71.12.91.1-1.11.1-1.11.0-0.4-0.61.2-0.90.9-0.91.0-1.30.91.61.7-0.90.9-0.91.4-1.4-0.7-0.21.2-0.6-0.7
Locomotor testing distance0.81.45.21.2-1.21.2-1.20.60.1-0.31.2-1.01.0-1.01.1-2.31.41.61.8-0.61.2-1.21.7-1.7-0.6-0.20.9-0.6-0.7
Locomotor testing rearing0.91.56.01.4-1.71.4-1.41.7-1.10.50.9-1.01.0-1.01.0-2.41.5-0.00.10.41.6-1.61.6-1.6-0.0-0.80.4-0.8-0.7
Light reinforcement 10.50.95.5-0.30.6-0.30.3-2.32.3-0.60.3-0.30.3-0.30.1-0.50.52.02.1-1.30.1-0.1-0.10.1-0.7-0.10.6-0.2-0.2
Light reinforcement 20.40.53.60.00.30.0-0.0-1.91.60.10.5-0.60.6-0.60.5-0.20.70.91.0-0.10.3-0.30.1-0.10.00.7-0.60.6-0.6
Reaction time number correct1.11.62.7-1.51.5-1.51.5-1.11.2-1.5-1.31.1-1.11.1-1.21.3-1.31.51.3-1.5-1.61.6-0.90.9-1.1-0.11.3-0.31.2
Reaction time mean minus median0.30.30.8-0.70.6-0.70.7-0.50.3-0.0-0.80.6-0.60.6-0.70.7-0.3-0.5-0.50.1-0.60.6-0.90.9-0.2-0.7-0.0-0.50.6
Reaction time mean minus median AUC0.91.22.6-1.11.2-1.11.1-0.70.8-0.9-1.01.0-1.01.0-1.21.6-1.10.60.6-1.2-1.51.5-1.51.5-0.7-0.81.1-0.81.0
Reaction time num false alarms2.33.16.32.1-2.12.1-2.11.4-1.31.31.9-1.91.9-1.92.0-1.91.6-0.1-0.11.12.5-2.52.2-2.20.71.9-0.81.5-1.8
Reaction time num false alarms AUC2.73.87.12.2-2.22.2-2.21.4-1.41.62.2-2.12.1-2.12.2-1.91.8-0.4-0.41.52.7-2.72.4-2.41.12.2-1.21.9-2.0
Reaction time trials correct on left1.11.62.7-1.51.5-1.51.5-1.11.2-1.5-1.31.1-1.11.1-1.21.3-1.31.51.3-1.5-1.61.6-0.90.9-1.1-0.11.3-0.31.2
Reaction time trials on left1.01.52.6-1.41.5-1.41.4-1.11.2-1.4-1.21.1-1.11.1-1.21.3-1.21.41.3-1.4-1.61.6-0.90.9-1.00.01.2-0.21.2
Reaction time mean0.50.71.5-0.80.7-0.80.80.2-0.1-0.5-1.00.9-0.90.9-1.10.9-0.9-0.1-0.1-0.3-1.01.0-1.21.2-0.5-0.90.6-0.91.0
Reaction time mean AUC0.81.12.2-1.00.8-1.01.00.2-0.0-0.7-1.21.2-1.21.2-1.41.0-1.1-0.0-0.0-0.4-1.11.1-1.51.5-0.7-1.30.8-1.21.3
Median of all reaction times0.40.61.4-0.70.5-0.70.70.4-0.2-0.5-0.80.8-0.80.8-1.00.8-0.90.00.0-0.4-0.90.9-1.21.2-0.5-0.90.7-0.90.9
Reaction time omissions0.20.30.70.1-0.10.1-0.1-0.3-0.20.60.3-0.60.6-0.60.20.60.5-0.8-0.80.6-0.40.4-0.50.50.80.4-0.80.6-0.5
Reaction time false alarm rate3.34.69.12.5-2.62.5-2.51.9-1.92.02.2-2.12.1-2.12.3-2.32.1-1.1-1.11.93.0-3.02.4-2.41.31.7-1.51.5-2.1
Reaction time premature initiation rate0.50.62.50.8-0.60.8-0.8-0.60.60.41.6-1.01.0-1.00.9-0.91.10.50.6-0.20.7-0.70.8-0.80.70.3-0.20.4-0.9
Reaction time premature initiations0.20.31.50.00.20.0-0.0-1.21.2-0.30.8-0.40.4-0.40.3-0.20.41.11.2-0.8-0.10.10.3-0.30.20.40.30.4-0.3
Std. dev. reaction times0.30.41.1-0.50.4-0.50.50.1-0.30.2-0.50.5-0.50.5-0.70.9-0.4-1.0-1.00.4-0.80.8-0.90.90.4-0.4-0.2-0.20.5
Reaction time trials completed1.01.52.6-1.41.5-1.41.4-1.11.2-1.4-1.21.1-1.11.1-1.21.3-1.21.41.3-1.4-1.61.6-0.90.9-1.00.01.2-0.21.2
Reaction time trials AUC1.01.42.7-1.41.4-1.41.4-1.11.1-1.4-1.11.0-1.01.0-1.11.3-1.21.31.2-1.3-1.61.6-0.90.9-0.90.01.1-0.11.2
Social response proportion0.30.30.5-0.70.6-0.70.7-0.50.6-0.7-0.20.6-0.60.6-0.60.6-0.50.60.6-0.4-0.50.5-0.60.6-0.3-0.30.5-0.30.6
Social responses0.10.20.60.4-0.50.4-0.40.5-0.1-0.30.4-0.20.2-0.20.2-0.20.20.70.7-0.50.2-0.20.2-0.2-0.5-0.30.8-0.4-0.2
Social time0.10.10.4-0.30.2-0.30.3-0.00.10.1-0.50.7-0.70.7-0.4-0.4-0.3-0.3-0.50.0-0.40.40.1-0.1-0.0-0.20.20.00.6
Conditioned locomotion0.20.21.90.3-0.30.3-0.3-0.50.40.60.4-0.50.5-0.50.4-1.40.7-0.2-0.20.50.4-0.40.4-0.40.40.5-0.50.5-0.3
Cocaine response after cond. corrected0.50.61.8-0.90.9-0.90.9-0.40.3-0.5-1.11.0-1.01.0-0.80.6-1.10.1-0.1-0.5-1.31.3-0.40.4-0.50.10.5-0.00.9
Cocaine response after cond. not corrected0.90.92.7-1.00.9-1.01.00.7-0.4-0.8-1.51.5-1.51.5-1.00.7-1.70.1-0.1-0.5-1.21.2-0.20.2-0.9-0.20.9-0.51.3
Cocaine response before conditioning0.30.31.3-0.20.1-0.20.21.2-0.6-0.7-0.20.7-0.70.7-0.30.3-0.80.60.5-0.40.2-0.20.1-0.1-0.8-0.60.8-0.80.6
Saline control response0.50.74.20.6-0.70.6-0.6-0.40.60.60.4-0.80.8-0.80.7-2.01.20.40.50.41.4-1.40.8-0.8-0.3-0.1-0.5-0.1-0.6
Condit. Reinf. active minus inactive responses3.84.79.52.3-2.42.3-2.32.1-1.91.42.2-2.32.3-2.32.5-2.71.9-0.3-0.41.32.8-2.83.1-3.10.92.6-0.82.0-2.0
Condit. Reinf. active-inactive response ratio1.71.85.91.3-1.41.3-1.31.6-1.41.10.9-1.01.0-1.01.4-1.91.0-0.6-0.81.11.6-1.62.4-2.40.51.5-0.61.2-0.8
Condit. Reinf. active responses4.66.411.22.7-2.82.7-2.71.7-1.71.93.1-2.92.9-2.92.8-3.32.6-0.5-0.51.83.4-3.43.0-3.01.62.8-1.52.4-2.6
Condit. Reinf. inactive responses2.22.77.11.8-1.81.8-1.80.2-0.31.12.7-2.32.3-2.31.8-2.12.10.20.40.62.1-2.11.0-1.01.31.3-0.71.3-2.1
Condit. Reinf. lever presses1.41.94.91.5-1.61.5-1.51.2-0.90.62.0-1.61.6-1.61.5-1.81.50.40.50.82.2-2.21.6-1.60.60.8-0.40.7-1.3
Condit. Reinf. lever reinforcers received3.95.59.62.5-2.62.5-2.51.6-1.51.82.9-2.72.7-2.72.6-3.02.4-0.6-0.61.73.1-3.12.7-2.71.62.6-1.52.3-2.4
Pavlov. Cond. lever latency0.20.31.1-0.50.5-0.50.5-0.80.5-0.0-0.80.4-0.40.4-0.40.7-0.2-0.5-0.4-0.3-1.01.0-0.70.7-0.1-0.6-0.0-0.30.3
Pavlov. Cond. magazine entry latency1.82.14.8-1.41.2-1.41.40.50.0-1.5-1.91.8-1.81.8-1.81.4-2.20.80.6-1.0-1.31.3-1.61.6-1.6-1.11.4-1.41.7
Pavlov. Cond. change in total contacts0.30.41.30.6-0.70.6-0.61.1-0.80.30.7-0.40.4-0.40.5-1.00.2-0.0-0.10.71.1-1.10.7-0.70.30.7-0.20.5-0.3
Pavlov. Cond. index score0.10.21.1-0.1-0.1-0.10.11.0-0.6-0.5-0.10.4-0.40.4-0.3-0.1-0.60.50.40.00.4-0.4-0.00.0-0.50.00.4-0.20.4
Pavlov. Cond. latency score0.20.21.3-0.20.0-0.20.21.1-0.6-0.6-0.30.5-0.50.5-0.40.0-0.80.60.5-0.10.3-0.3-0.10.1-0.7-0.10.6-0.40.6
Pavlov. Cond. lever contacts0.20.21.00.4-0.50.4-0.40.4-0.2-0.00.8-0.40.4-0.40.4-0.60.40.50.50.31.0-1.00.6-0.60.10.5-0.10.3-0.3
Pavlov. Cond. magazine entry number2.53.16.21.8-1.61.8-1.8-0.4-0.22.02.1-2.22.2-2.22.1-1.62.5-1.2-1.11.31.6-1.61.7-1.71.91.4-1.81.7-2.1
Pavlov. Cond. intertrial magazine entries12.115.623.44.1-3.84.1-4.10.4-1.54.44.0-4.64.6-4.64.5-4.14.8-3.0-2.83.84.1-4.13.9-3.93.73.7-4.34.1-4.6
Pavlov. Cond. lever-magazine prob. diff.0.10.21.0-0.2-0.0-0.20.21.0-0.6-0.5-0.20.4-0.40.4-0.40.0-0.80.50.4-0.00.3-0.3-0.20.2-0.50.00.5-0.20.5
Pavlov. Cond. response bias0.10.10.30.1-0.20.1-0.10.6-0.4-0.20.4-0.10.1-0.10.0-0.1-0.20.40.40.10.5-0.50.1-0.10.00.40.20.20.0
Conditioned reinforcement - actives0.20.20.60.2-0.30.2-0.2-0.30.40.3-0.0-0.30.3-0.30.5-0.80.60.20.2-0.10.7-0.70.6-0.6-0.40.30.10.1-0.4
Conditioned reinforcement - inactives2.02.24.71.9-1.81.9-1.90.7-1.01.21.7-2.02.0-2.01.9-0.91.8-0.7-0.60.91.3-1.31.5-1.51.01.1-1.01.2-2.2
Conditioned locomotion1.82.13.61.5-1.41.5-1.5-0.0-0.31.41.8-1.71.7-1.71.9-1.41.9-0.5-0.40.71.9-1.91.8-1.81.21.5-1.01.4-1.7
Intermittent access intake day 1-15 change0.70.73.10.6-0.60.6-0.61.0-1.21.20.4-0.30.3-0.30.4-0.70.5-1.7-1.81.40.5-0.50.6-0.61.30.3-1.10.6-0.2
Intermittent access intake escalation0.30.31.70.2-0.20.2-0.20.6-0.80.70.10.0-0.00.00.0-0.30.2-1.2-1.31.10.2-0.20.2-0.21.0-0.0-0.90.30.1
Intermittent access intake escalation 21.61.64.41.1-1.11.1-1.11.1-1.51.71.0-0.90.9-0.90.8-0.91.0-2.1-2.11.90.9-0.90.7-0.72.00.8-1.81.2-0.9
Intermitt. access day 1 inactive lever presses3.74.07.42.5-2.62.5-2.51.6-1.51.51.9-2.22.2-2.22.5-2.32.0-0.4-0.40.92.4-2.42.7-2.70.41.6-0.61.2-2.3
Intermitt. access day 15 inactive lever presses1.41.53.61.5-1.41.5-1.50.2-0.41.31.2-1.41.4-1.41.6-1.71.9-0.9-0.80.81.0-1.01.7-1.70.70.2-0.80.5-1.4
Intermitt. access escalation Index2.72.45.9-1.41.4-1.41.40.50.0-1.4-2.02.0-2.02.0-1.91.6-2.40.80.6-1.3-1.91.9-1.21.2-1.5-1.01.8-1.22.0
Intermittent access day 1 total infusions0.40.40.90.6-0.50.6-0.6-0.60.50.00.6-0.90.9-0.90.9-0.60.80.90.9-0.60.4-0.40.7-0.7-0.50.70.30.4-0.9
Intermittent access day 15 total infusions0.20.30.60.5-0.50.5-0.5-0.20.00.60.6-0.60.6-0.60.7-0.60.8-0.3-0.30.30.2-0.20.7-0.70.50.5-0.40.6-0.6
Intermittent access terminal intake (last 3 days)2.12.33.41.7-1.71.7-1.70.4-0.81.71.6-1.81.8-1.81.8-1.51.9-1.2-1.21.21.3-1.31.4-1.41.41.5-1.41.6-1.8
Intermittent access total infusions2.02.24.01.8-1.71.8-1.80.3-0.61.31.8-1.91.9-1.92.0-1.61.9-0.3-0.30.61.4-1.41.8-1.80.81.5-0.81.4-1.9
Intermittent access day 1 locomotion2.32.34.31.8-1.61.8-1.80.1-0.31.11.9-1.91.9-1.92.0-1.52.10.10.20.31.6-1.61.8-1.80.61.6-0.61.3-2.0
Intermittent access day 15 total locomotion4.95.27.72.6-2.52.6-2.60.9-1.42.12.7-2.62.6-2.62.8-2.32.7-1.1-1.01.62.6-2.62.7-2.71.92.2-1.82.1-2.6
Intermittent access total locomotion6.77.612.93.2-3.03.2-3.20.6-1.12.43.6-3.33.3-3.33.5-2.63.5-0.7-0.51.43.0-3.03.2-3.22.12.4-1.72.4-3.4
Intermittent access standard deviation1.11.13.01.2-1.11.2-1.20.1-0.31.01.4-1.31.3-1.31.3-1.11.7-0.6-0.40.81.1-1.11.0-1.01.10.5-0.90.7-1.3
Cocaine induced anxiety0.20.30.6-0.60.5-0.60.6-0.40.5-0.8-0.00.4-0.40.4-0.50.8-0.30.60.6-0.5-0.50.5-0.50.5-0.1-0.40.5-0.40.6
Post-drug Anxiety0.60.71.5-1.21.1-1.21.2-1.00.9-0.9-0.50.9-0.90.9-0.91.0-0.70.60.5-0.4-0.90.9-0.80.8-0.1-0.40.2-0.31.0
Baseline Anxiety1.11.12.0-1.41.4-1.41.4-1.11.1-1.0-1.21.1-1.11.1-1.11.1-1.00.80.7-0.9-1.21.2-1.01.0-0.9-0.70.6-0.71.1
Lifetime Intake2.22.44.51.9-1.81.9-1.90.2-0.31.11.9-2.02.0-2.02.1-1.82.10.10.20.31.6-1.61.7-1.70.51.4-0.51.2-2.1
Incentive Sensitization - Responses2.72.74.51.6-1.61.6-1.60.5-0.91.91.3-1.71.7-1.71.9-1.81.7-1.2-1.31.51.5-1.52.1-2.11.42.1-1.62.0-1.7
Incentive Sensitization - Breakpoint2.72.74.61.7-1.61.7-1.70.7-1.11.91.2-1.61.6-1.61.9-1.81.6-1.3-1.41.61.5-1.52.1-2.11.32.1-1.62.0-1.7
Progressive ratio test 1 active lever presses2.93.05.42.1-2.02.1-2.10.5-0.61.31.7-2.12.1-2.12.3-2.22.10.20.20.42.0-2.02.2-2.20.21.8-0.51.4-2.2
Progressive ratio test 1 breakpoint3.53.66.52.2-2.22.2-2.20.3-0.31.41.8-2.42.4-2.42.5-2.62.40.20.30.52.2-2.22.3-2.30.11.8-0.61.4-2.4
Progressive ratio test 1 inactive lever presses3.53.76.52.5-2.42.5-2.50.8-0.81.32.0-2.42.4-2.42.5-2.42.20.40.50.22.1-2.12.2-2.20.11.7-0.21.3-2.5
Progressive ratio test 2 active lever presses3.33.55.42.0-2.02.0-2.00.2-0.61.81.9-2.22.2-2.22.3-2.22.3-0.6-0.61.12.0-2.02.2-2.21.12.3-1.32.0-2.2
Progressive ratio test 2 breakpoint3.94.36.62.2-2.22.2-2.20.5-0.92.12.0-2.32.3-2.32.6-2.42.5-0.9-1.01.42.2-2.22.6-2.61.42.4-1.52.2-2.4
Progressive ratio test 2 inactive lever presses3.44.07.02.2-2.02.2-2.2-0.1-0.41.72.5-2.52.5-2.52.6-2.12.6-0.5-0.41.01.8-1.82.2-2.21.42.2-1.42.1-2.6
Total sessions with >9 infusions0.91.05.9-0.30.4-0.30.3-1.41.6-1.1-0.1-0.10.1-0.10.2-0.20.22.42.4-1.7-0.10.10.2-0.2-1.6-0.21.4-0.6-0.2
Short access day 1 total inactive lever presses0.91.02.41.3-1.21.3-1.30.6-0.60.41.1-1.31.3-1.31.5-0.71.10.30.40.01.0-1.01.5-1.5-0.00.6-0.00.4-1.4
Short access day 10 total inactive lever presses0.90.92.31.2-1.11.2-1.20.1-0.41.01.5-1.21.2-1.21.0-0.81.2-0.7-0.70.60.9-0.90.5-0.51.30.6-0.70.9-1.2
Short access day 1 total infusions1.01.05.10.5-0.40.5-0.5-0.91.2-0.60.6-0.80.8-0.80.8-0.90.92.22.3-1.50.6-0.60.8-0.8-1.40.01.2-0.4-0.9
Short access day 10 total infusions4.75.29.72.8-2.62.8-2.80.3-0.71.92.8-3.03.0-3.03.0-2.53.1-0.5-0.30.92.4-2.42.1-2.11.21.8-1.31.8-3.1
Short access total infusions1.92.13.81.9-1.81.9-1.90.3-0.20.61.7-1.91.9-1.91.9-2.01.90.91.0-0.31.7-1.71.4-1.4-0.30.70.20.4-2.0
Short access day 1 locomotion2.02.14.61.3-1.11.3-1.3-1.31.10.62.1-1.91.9-1.91.9-1.52.21.31.5-0.51.4-1.41.5-1.50.31.2-0.10.9-2.0
Short access day 10 total locomotion8.39.116.23.3-3.23.3-3.30.6-1.12.93.5-3.63.6-3.63.7-3.44.0-1.1-0.92.03.7-3.73.5-3.52.22.4-2.22.4-3.6
Short access total locomotion3.43.57.62.2-2.02.2-2.2-0.30.21.22.4-2.42.4-2.42.4-2.22.80.70.90.12.3-2.32.1-2.10.41.1-0.50.9-2.5
Compulsive drug intake0.80.81.9-0.70.6-0.70.70.7-0.4-1.1-0.81.1-1.11.1-0.91.1-1.40.40.2-0.9-1.11.1-0.50.5-0.7-0.61.3-0.71.0
One hour access (0.3 mA shock)0.81.01.91.3-1.41.3-1.30.9-0.90.90.8-1.11.1-1.11.1-1.31.0-0.5-0.50.61.0-1.00.9-0.90.40.9-0.40.7-1.2
One hour access (shock baseline)1.21.32.41.3-1.21.3-1.30.1-0.31.31.1-1.41.4-1.41.4-1.51.5-0.5-0.40.91.3-1.31.0-1.00.71.0-1.11.0-1.4
Number of responses in last shaping day0.20.30.50.4-0.40.4-0.4-0.10.3-0.00.4-0.40.4-0.40.6-0.70.60.70.7-0.60.5-0.50.7-0.7-0.50.00.5-0.1-0.4
Context. condit. distance diff. score0.00.00.1-0.10.0-0.10.10.2-0.0-0.30.20.2-0.20.2-0.2-0.3-0.30.10.1-0.2-0.00.0-0.30.30.1-0.40.2-0.30.1
Locomotion velocity, session 10.60.72.30.9-0.80.9-0.90.4-0.60.60.5-1.01.0-1.01.2-0.51.0-0.2-0.20.40.7-0.71.5-1.50.10.7-0.40.6-0.9
Locomotion distance, session 10.20.30.80.4-0.40.4-0.4-0.30.1-0.20.6-0.90.9-0.90.7-0.00.80.60.7-0.40.2-0.20.5-0.50.10.50.10.5-0.7
Locomotion velocity, session 20.81.04.01.3-1.51.3-1.32.0-1.70.60.1-0.80.8-0.80.8-1.10.6-0.5-0.50.51.2-1.21.0-1.0-0.5-0.10.2-0.3-0.7
Locomotion distance, session 20.10.21.00.3-0.40.3-0.30.8-0.5-0.4-0.2-0.30.3-0.30.2-0.30.10.70.7-0.50.3-0.30.5-0.5-1.0-0.10.8-0.3-0.1
Locomotion velocity, session 30.81.03.8-0.60.6-0.60.6-0.20.6-1.3-1.10.7-0.70.7-0.60.5-0.81.61.6-1.5-0.60.6-0.30.3-1.9-1.11.6-1.40.7
Locomotion distance, session 30.10.10.60.3-0.30.3-0.30.8-0.6-0.20.0-0.10.1-0.10.2-0.2-0.30.30.2-0.40.1-0.10.2-0.2-0.50.10.6-0.2-0.1
Stereotopy head waving bouts, day 30.70.91.7-1.21.3-1.21.2-1.31.3-0.9-1.21.0-1.01.0-0.70.9-0.70.90.8-0.8-0.90.9-0.40.4-1.0-0.60.5-0.70.9
Stereotopy head waving duration, day 30.81.02.0-1.21.3-1.21.2-1.31.4-1.0-1.31.0-1.01.0-0.80.8-0.91.11.1-0.9-0.90.9-0.60.6-1.2-0.50.6-0.70.9
Locomotion velocity, session 70.10.10.5-0.10.1-0.10.10.2-0.2-0.3-0.40.3-0.30.3-0.20.5-0.2-0.2-0.2-0.3-0.60.6-0.30.3-0.2-0.70.4-0.60.2
Locomotion distance, session 70.00.00.20.0-0.10.0-0.00.00.0-0.10.3-0.20.2-0.2-0.1-0.40.20.00.0-0.3-0.30.3-0.30.30.30.10.30.20.0
Stereotopy head waving bouts, day 71.01.13.5-1.00.9-1.01.0-0.20.7-1.2-1.61.2-1.21.2-0.90.4-1.11.31.2-1.1-0.60.6-0.30.3-1.9-1.11.2-1.41.2
Stereotopy head waving duration, day 72.42.96.3-1.71.6-1.71.7-0.00.7-1.7-2.52.2-2.22.2-1.81.1-2.21.41.3-1.4-1.21.2-0.90.9-2.5-1.61.7-2.02.1
Locomotion velocity, session 81.11.32.31.4-1.41.4-1.41.4-1.51.20.9-0.90.9-0.91.2-1.00.8-1.2-1.21.11.2-1.21.3-1.30.70.6-0.80.6-1.1
Locomotion distance, session 80.10.10.60.5-0.60.5-0.50.8-0.5-0.00.5-0.40.4-0.40.3-0.70.10.10.1-0.00.5-0.50.2-0.2-0.00.10.2-0.0-0.3
Degree of sensitization distance0.30.31.20.2-0.20.2-0.2-0.50.20.60.6-0.60.6-0.60.3-0.60.9-0.6-0.60.70.2-0.20.1-0.11.10.9-0.91.1-0.4
Degree of sensitization stereotypy1.51.75.1-1.00.8-1.01.00.50.2-1.6-1.71.3-1.31.3-1.20.5-1.41.51.5-1.4-0.60.6-0.50.5-2.3-1.71.8-2.01.5
Condit. Reinf. active minus inactive responses1.31.55.31.2-1.31.2-1.20.8-0.60.91.4-1.11.1-1.11.3-2.31.3-0.2-0.20.81.8-1.81.8-1.80.70.9-0.60.8-0.9
Condit. Reinf. active-inactive response ratio0.50.62.80.6-0.70.6-0.60.9-0.60.50.6-0.30.3-0.30.6-1.70.6-0.4-0.50.81.1-1.11.3-1.30.50.6-0.50.5-0.3
Condit. Reinf. active responses1.92.46.01.5-1.61.5-1.50.7-0.61.42.0-1.51.5-1.51.7-2.41.7-0.3-0.31.02.1-2.12.0-2.01.21.5-0.91.4-1.4
Condit. Reinf. inactive responses1.01.23.01.1-1.11.1-1.1-0.1-0.31.01.7-1.41.4-1.41.3-0.91.2-0.2-0.20.51.0-1.01.1-1.11.21.5-0.71.4-1.4
Incentive salience index mean1.31.64.21.3-1.41.3-1.31.2-0.91.01.3-1.01.0-1.01.4-2.01.2-0.3-0.30.91.9-1.92.1-2.10.50.9-0.50.7-0.9
Condit. Reinf. lever presses0.20.21.10.2-0.40.2-0.20.6-0.20.10.30.1-0.10.10.3-0.60.10.40.3-0.00.8-0.81.0-1.0-0.4-0.20.4-0.30.1
Time in familiar zone, hab. session 11.31.22.90.9-0.90.9-0.90.3-0.71.51.3-1.01.0-1.00.9-1.31.1-1.3-1.31.40.9-0.90.6-0.61.71.2-1.41.5-0.9
Time in novel zone, hab. session 11.41.42.7-1.01.0-1.01.0-0.40.7-1.5-1.31.0-1.01.0-1.01.4-1.01.21.3-1.4-1.11.1-1.11.1-1.6-1.61.4-1.60.9
Total zone transitions, hab. session 10.30.40.90.6-0.60.6-0.60.1-0.1-0.20.8-0.90.9-0.90.8-0.50.90.70.8-0.40.5-0.50.9-0.9-0.10.10.40.1-0.7
Total locomotion distance, hab. session 10.91.32.91.3-1.21.3-1.30.3-0.50.21.2-1.61.6-1.61.6-0.71.70.60.7-0.21.0-1.01.7-1.70.00.50.00.4-1.5
Locomotion velocity, hab. session 11.11.63.91.3-1.41.3-1.30.4-0.60.51.3-1.71.7-1.71.7-1.01.70.20.40.21.3-1.32.0-2.00.30.9-0.40.8-1.5
Time in familiar zone, hab. session 21.81.93.11.5-1.61.5-1.51.5-1.51.51.4-1.21.2-1.21.3-1.81.1-1.3-1.41.41.6-1.61.2-1.21.31.0-1.11.1-1.2
Time in novel zone, hab. session 21.11.13.6-1.11.2-1.11.1-1.21.0-1.2-1.30.7-0.70.7-0.91.9-0.80.80.9-1.0-1.41.4-1.21.2-0.9-0.70.6-0.70.7
Total zone transitions, hab. session 20.20.20.60.5-0.60.5-0.50.3-0.2-0.0-0.1-0.50.5-0.50.5-0.60.50.50.5-0.20.5-0.50.5-0.5-0.8-0.20.3-0.3-0.5
Total locomotion distance, hab. session 20.60.82.00.9-0.80.9-0.9-0.40.10.50.9-1.41.4-1.41.2-0.81.40.20.30.10.8-0.80.9-0.90.30.6-0.50.6-1.3
Locomotion velocity, hab. session 20.50.71.70.8-0.70.8-0.8-0.50.20.40.8-1.31.3-1.31.2-0.71.30.20.30.10.7-0.70.9-0.90.20.8-0.50.7-1.2
Novel to familiar place preference ratio0.60.61.30.9-0.80.9-0.90.3-0.50.61.2-1.01.0-1.00.9-0.20.8-0.4-0.40.50.8-0.80.5-0.50.80.7-0.60.7-1.1
Novelty place preference0.30.30.70.7-0.70.7-0.70.4-0.50.40.8-0.70.7-0.70.7-0.00.5-0.3-0.30.30.6-0.60.3-0.30.50.4-0.40.4-0.8
Time in novel zone, NPP test0.20.20.50.7-0.60.7-0.70.6-0.60.20.7-0.60.6-0.60.60.10.3-0.2-0.20.20.5-0.50.2-0.20.30.2-0.20.2-0.7
Total zone transitions, NPP test0.30.42.90.00.00.0-0.0-0.60.7-0.80.2-0.50.5-0.50.4-0.10.41.61.7-1.10.1-0.10.5-0.5-0.90.20.8-0.1-0.3
Total locomotion distance, NPP test0.71.02.21.1-1.11.1-1.10.2-0.40.41.2-1.51.5-1.51.4-0.61.50.20.30.00.7-0.71.4-1.40.50.8-0.20.8-1.3
Locomotion velocity, NPP test0.50.71.90.6-0.50.6-0.6-0.90.60.10.9-1.31.3-1.31.1-0.51.40.80.9-0.40.4-0.41.0-1.00.10.7-0.00.6-1.1
Pavlov. Cond. lever latency1.01.34.8-1.21.3-1.21.2-1.10.8-0.5-1.00.9-0.90.9-1.41.2-1.1-0.4-0.4-0.1-1.71.7-2.22.20.3-0.5-0.2-0.10.9
Pavlov. Cond. magazine entry latency2.12.76.71.9-1.91.9-1.91.3-1.11.41.3-1.61.6-1.62.0-2.01.7-0.4-0.41.02.3-2.32.6-2.60.21.2-0.70.9-1.6
Pavlov. Cond. change in total contacts1.51.64.71.5-1.51.5-1.50.9-0.71.01.3-1.11.1-1.11.6-1.81.30.00.10.41.9-1.92.2-2.20.10.3-0.10.1-1.2
Pavlov. Cond. index score1.82.25.91.8-1.81.8-1.81.3-1.11.11.2-1.41.4-1.41.9-1.71.5-0.0-0.00.62.2-2.22.4-2.4-0.10.9-0.30.6-1.5
Pavlov. Cond. latency score1.51.95.21.6-1.61.6-1.61.3-1.00.91.1-1.21.2-1.21.7-1.61.30.10.10.42.1-2.12.3-2.3-0.30.7-0.10.4-1.3
Pavlov. Cond. lever contacts0.81.03.71.1-1.21.1-1.11.1-0.70.60.8-0.60.6-0.61.2-1.30.90.20.20.21.5-1.51.9-1.9-0.30.10.1-0.1-0.7
Pavlov. Cond. magazine entry number1.31.64.5-1.41.4-1.41.4-0.90.7-1.0-0.91.1-1.11.1-1.61.6-1.20.20.2-0.7-1.91.9-2.12.10.0-0.80.4-0.51.2
Pavlov. Cond. intertrial magazine entries0.91.13.60.7-0.70.7-0.7-1.10.80.61.9-1.51.5-1.50.9-1.51.40.60.70.00.9-0.90.5-0.51.11.4-0.51.4-1.2
Pavlov. Cond. lever-magazine prob. diff.1.51.85.11.6-1.61.6-1.61.1-0.90.91.1-1.31.3-1.31.7-1.51.30.10.10.52.0-2.02.3-2.3-0.20.8-0.20.4-1.3
Pavlov. Cond. response bias1.51.86.41.5-1.51.5-1.51.1-0.81.01.1-1.21.2-1.21.7-1.61.40.10.10.52.0-2.02.5-2.5-0.10.8-0.20.5-1.2
Bone: apparent density1.01.63.91.3-1.11.3-1.30.5-0.91.11.5-1.31.3-1.31.7-0.31.2-0.7-0.71.01.2-1.22.0-2.01.21.7-1.21.6-1.5
Bone surface6.311.115.43.6-3.63.6-3.62.9-3.53.03.5-3.43.4-3.43.8-2.22.9-2.5-2.63.03.4-3.43.9-3.92.93.9-2.83.6-3.5
Bone volume4.67.811.73.0-2.93.0-3.01.9-2.52.53.2-2.92.9-2.93.3-1.82.6-1.8-1.82.42.9-2.93.4-3.42.53.4-2.43.2-3.1
Bone: connectivity density1.92.95.21.8-1.71.8-1.81.2-1.61.51.7-1.81.8-1.82.1-0.91.6-1.2-1.31.51.6-1.62.3-2.31.52.1-1.52.0-1.9
Bone: cortical apparent density4.15.38.2-2.32.6-2.32.3-2.62.7-2.5-1.31.9-1.91.9-2.22.9-1.82.42.5-2.8-2.72.7-2.72.7-1.5-2.22.1-2.01.7
Bone: cortical area1.72.66.41.9-1.71.9-1.90.4-0.50.62.5-2.22.2-2.22.1-0.81.80.60.80.11.9-1.91.7-1.70.91.4-0.51.3-2.2
Bone: cortical porosity4.95.312.72.6-2.72.6-2.62.9-2.72.11.6-1.81.8-1.82.5-2.72.0-1.5-1.51.93.0-3.03.6-3.60.71.2-1.21.0-1.9
Bone: cortical porosity2.52.77.81.9-1.91.9-1.92.0-1.81.21.3-1.41.4-1.41.9-1.81.4-0.4-0.40.92.3-2.32.8-2.80.31.0-0.40.7-1.4
Bone: cortical thickness4.67.520.0-2.32.6-2.32.3-2.83.2-3.6-1.31.7-1.71.7-1.93.3-1.84.24.5-4.1-2.42.4-2.22.2-2.8-2.83.4-3.01.6
Bone: cortical thickness2.83.37.3-1.41.4-1.41.4-0.71.3-2.6-0.41.3-1.31.3-1.62.4-1.42.52.7-2.7-1.71.7-1.81.8-1.4-2.42.6-2.31.3
Bone: cortical tissue density3.95.17.6-2.32.5-2.32.3-2.52.6-2.4-1.31.9-1.91.9-2.12.8-1.82.22.4-2.7-2.62.6-2.62.6-1.4-2.22.1-2.01.8
Bone: elastic displacement1.82.13.7-1.41.5-1.41.4-0.50.9-1.9-1.31.5-1.51.5-1.11.6-1.51.71.7-1.8-1.31.3-0.70.7-1.7-1.61.7-1.81.3
Bone: elastic work0.20.20.60.4-0.20.4-0.4-0.1-0.0-0.30.8-0.40.4-0.40.70.60.50.50.7-0.50.2-0.20.7-0.70.0-0.40.3-0.3-0.7
Bone: endosteal estimation16.435.343.66.4-6.66.4-6.45.2-5.96.05.8-6.06.0-6.06.1-6.05.6-5.1-5.26.16.6-6.66.1-6.15.35.9-5.35.8-5.7
Bone: endosteal perimeter17.335.544.16.4-6.56.4-6.44.7-5.56.05.7-6.16.1-6.16.3-5.95.5-4.8-4.95.96.6-6.66.3-6.35.16.5-5.46.2-6.0
Bone: final force1.32.16.11.7-1.61.7-1.71.2-1.40.62.5-1.81.8-1.81.7-0.11.2-0.1-0.00.41.4-1.41.4-1.41.51.7-0.61.6-1.9
Bone: final moment1.42.36.41.8-1.71.8-1.81.3-1.50.72.5-1.81.8-1.81.8-0.11.2-0.2-0.10.51.5-1.51.5-1.51.51.7-0.61.6-1.9
Bone: marrow area16.034.542.56.3-6.56.3-6.35.2-5.96.05.7-5.85.8-5.86.0-5.95.5-5.1-5.26.16.5-6.56.0-6.05.35.8-5.35.8-5.6
Bone: maximum diameter5.19.413.53.4-3.43.4-3.42.2-2.62.73.6-3.43.4-3.43.4-2.52.8-1.6-1.62.43.6-3.63.2-3.22.53.7-2.43.4-3.4
Bone: maximum force2.23.710.32.1-1.92.1-2.10.6-1.01.03.2-2.62.6-2.62.3-0.82.10.10.20.61.9-1.91.8-1.82.02.5-1.02.3-2.5
Bone: maximum moment2.34.010.82.2-2.02.2-2.20.7-1.21.13.3-2.62.6-2.62.4-0.72.1-0.10.00.72.0-2.01.9-1.92.02.4-1.12.3-2.6
Bone: minimum diameter12.823.730.65.3-5.25.3-5.32.8-3.64.75.2-5.45.4-5.45.5-4.75.1-3.1-3.14.35.5-5.55.4-5.44.15.1-4.25.0-5.4
Bone: periosteal estimation10.421.328.05.2-5.15.2-5.23.4-4.04.25.3-5.15.1-5.15.1-4.24.6-2.9-2.83.95.3-5.34.9-4.94.04.7-3.64.5-5.0
Bone: periosteal perimeter5.08.312.23.3-3.23.3-3.32.5-2.72.43.2-3.03.0-3.03.3-2.42.4-1.4-1.52.23.4-3.43.5-3.52.13.4-2.03.0-3.1
Bone: post-yield work3.24.45.82.4-2.42.4-2.41.8-2.12.02.4-2.22.2-2.22.2-1.61.9-1.6-1.61.92.2-2.22.1-2.12.12.2-1.72.2-2.2
Bone: stiffness1.42.35.61.7-1.71.7-1.71.1-1.30.92.4-1.91.9-1.91.6-0.71.2-0.1-0.10.61.5-1.51.1-1.11.52.2-0.62.0-1.7
Bone: tissue strength1.11.02.1-1.00.9-1.01.0-0.40.6-1.3-1.10.8-0.80.8-1.01.1-1.11.41.4-1.4-1.11.1-0.90.9-1.3-0.41.3-0.71.0
Bone: trabecular number1.62.55.31.6-1.51.6-1.60.9-1.21.31.8-1.71.7-1.72.0-1.01.5-0.7-0.71.11.6-1.62.3-2.31.32.3-1.22.0-1.7
Bone: trabecular spacing0.40.61.4-0.60.5-0.60.6-0.10.4-0.4-1.10.8-0.80.8-1.00.1-0.80.10.1-0.4-0.60.6-1.11.1-0.9-1.20.6-1.10.9
Bone: trabecular thickness1.82.24.31.3-1.11.3-1.3-0.2-0.41.31.9-1.61.6-1.61.9-0.91.7-0.7-0.61.11.4-1.42.1-2.11.61.9-1.51.9-1.8
Bone: trabecular tissue density1.01.53.1-1.31.4-1.31.3-1.71.5-1.6-0.50.5-0.50.5-0.91.8-0.81.71.8-1.6-1.41.4-1.21.2-0.70.01.0-0.20.7
Breakpoint value in progressive ratio session0.40.41.90.7-0.80.7-0.71.0-0.60.5-0.4-0.30.3-0.30.5-1.40.3-0.1-0.20.30.9-0.90.8-0.8-0.8-0.00.1-0.2-0.3
Distance traveled before self-admin0.80.82.5-0.80.7-0.80.80.6-0.3-0.7-1.61.2-1.21.2-1.00.7-1.60.40.2-0.5-0.90.9-0.70.7-1.2-0.30.9-0.51.2
Distance traveled after self-admin0.40.41.6-0.20.0-0.20.21.3-0.7-0.5-0.80.8-0.80.8-0.7-0.0-1.20.30.2-0.4-0.00.0-0.30.3-1.0-0.21.0-0.60.8
Delta time in closed arm before/after self-admin0.30.31.40.4-0.40.4-0.41.1-1.20.40.3-0.10.1-0.10.40.1-0.1-0.6-0.70.60.2-0.20.9-0.90.50.4-0.40.4-0.2
Delta time in open arm before/after self-admin1.11.13.3-1.21.3-1.21.2-1.81.8-0.7-1.00.8-0.80.8-1.20.4-0.50.80.8-0.8-0.90.9-1.51.5-0.7-0.70.4-0.60.9
Diff in mean of infusions in LGA sessions1.21.32.7-1.01.0-1.01.0-0.71.0-1.2-1.51.0-1.01.0-1.10.9-0.81.11.2-1.3-1.01.0-1.21.2-1.5-1.61.4-1.61.0
Extinction: sum of active levers before priming0.10.10.40.10.00.1-0.1-0.50.60.30.5-0.20.2-0.20.1-0.60.30.30.30.00.5-0.5-0.30.30.20.3-0.20.3-0.3
Active lever presses in extinction session 61.21.22.61.3-1.21.3-1.30.5-0.51.11.1-1.21.2-1.21.2-1.61.3-0.5-0.50.91.5-1.50.8-0.80.60.7-0.80.8-1.2
Delta distance traveled before/after self-admin0.30.41.4-0.20.1-0.20.20.10.3-0.8-0.20.3-0.30.3-0.40.2-0.30.91.0-1.00.1-0.1-0.50.5-0.9-1.01.2-1.20.2
Delta ambulatory time before/after self-admin0.10.10.20.2-0.20.2-0.20.00.1-0.00.5-0.30.3-0.30.2-0.30.20.30.4-0.30.4-0.40.1-0.10.0-0.10.3-0.2-0.3
Time in closed arm before self-admin1.01.13.5-0.60.5-0.60.60.30.2-1.5-0.90.8-0.80.8-0.91.0-0.81.31.4-1.4-0.50.5-0.90.9-1.6-1.81.7-1.90.8
Time in closed arm after self-admin0.40.43.10.2-0.30.2-0.21.8-1.6-0.3-0.70.4-0.40.4-0.20.8-0.8-0.3-0.40.0-0.10.10.0-0.0-0.6-0.80.5-0.80.3
Time in open arm before self-admin0.40.41.1-0.70.6-0.70.70.3-0.2-0.5-1.10.9-0.90.9-0.50.8-1.0-0.1-0.2-0.2-1.01.00.0-0.0-0.5-0.50.3-0.50.9
Time in open arm after self-admin0.30.32.3-0.70.7-0.70.7-1.51.30.1-0.20.2-0.20.2-0.4-0.30.10.10.00.0-0.50.5-0.60.60.10.3-0.40.40.3
Sum of active levers in priming session hrs 5-61.21.22.1-1.11.1-1.11.1-0.71.2-1.0-0.91.3-1.31.3-1.30.1-1.21.11.1-1.2-1.01.0-1.01.0-0.9-1.01.5-1.01.3
Time to tail flick, vehicle, before self-admin0.40.41.0-0.20.2-0.20.20.7-0.90.2-0.00.5-0.50.5-0.30.7-0.9-0.8-1.00.5-0.50.50.1-0.10.90.9-0.30.90.5
Time to tail flick, vehicle, after self-admin0.50.63.10.2-0.10.2-0.2-0.70.30.80.9-0.60.6-0.60.5-0.50.4-0.5-0.60.70.4-0.40.3-0.31.31.8-1.11.7-0.6
Time to tail flick, test, before self-admin0.50.51.0-0.80.8-0.80.80.1-0.20.1-0.60.9-0.90.9-0.70.5-0.7-1.0-1.00.3-0.90.9-0.50.50.7-0.6-0.2-0.30.8
Time to tail flick, test, after self-admin0.30.30.6-0.70.8-0.70.7-0.70.8-0.5-0.00.6-0.60.6-0.30.5-0.60.60.6-0.7-0.50.50.0-0.0-0.1-0.20.5-0.20.6
Delta time to tail flick, vehicle, before/after SA1.91.93.41.3-1.21.3-1.3-0.3-0.11.51.6-1.71.7-1.71.4-1.51.8-1.1-1.01.31.4-1.40.9-0.91.51.3-1.71.5-1.7
Delta time to tail flick, test, before/after SA0.10.10.3-0.10.1-0.10.1-0.20.3-0.20.30.0-0.00.0-0.10.2-0.20.60.5-0.4-0.00.0-0.10.1-0.10.50.30.30.1
Ambulatory time before self-admin0.40.42.2-0.40.3-0.40.40.8-0.5-0.5-1.50.8-0.80.8-0.60.3-1.10.20.0-0.3-0.60.6-0.20.2-1.2-0.00.6-0.40.8
Ambulatory time after self-admin0.10.10.80.1-0.20.1-0.10.9-0.5-0.2-0.30.2-0.20.2-0.1-0.2-0.50.40.3-0.30.3-0.30.0-0.0-0.8-0.00.7-0.40.2
Total heroin consumption0.20.21.00.4-0.40.4-0.41.0-0.60.0-0.1-0.00.0-0.00.2-1.0-0.20.40.3-0.00.6-0.60.6-0.6-0.60.30.4-0.10.1
Area under the delay curve0.20.21.5-0.40.6-0.40.4-1.21.0-0.20.20.0-0.00.00.00.1-0.00.60.6-0.3-0.30.30.2-0.20.10.9-0.00.60.0
Delay disc. indifference point, 0s delay0.60.71.2-1.01.1-1.01.0-0.90.8-0.5-0.80.8-0.80.8-0.91.0-1.10.50.4-0.6-0.80.8-1.01.0-0.30.00.4-0.10.8
Delay disc. indifference point, 16s delay0.40.42.7-0.50.7-0.50.5-1.61.5-0.40.00.0-0.00.00.0-0.20.21.01.0-0.6-0.30.30.2-0.2-0.20.70.20.50.1
Delay disc. indifference point, 2s delay0.70.75.50.4-0.30.4-0.4-0.4-0.10.61.0-0.70.7-0.70.8-0.10.3-0.2-0.40.60.4-0.40.8-0.81.32.3-1.02.0-0.7
Delay disc. indifference point, 24s delay1.11.12.40.7-0.40.7-0.7-1.31.00.41.5-1.41.4-1.41.3-1.01.50.60.70.10.8-0.81.2-1.20.71.5-0.71.4-1.2
Delay disc. indifference point, 4s delay0.70.71.4-1.11.1-1.11.1-0.40.5-0.8-0.71.1-1.11.1-1.01.0-1.20.70.6-0.7-0.80.8-0.60.6-0.6-0.30.7-0.51.1
Delay disc. indifference point, 8s delay0.60.62.5-0.91.1-0.90.9-1.61.4-0.7-0.20.5-0.50.5-0.40.6-0.40.90.9-0.9-0.90.9-0.30.3-0.30.30.40.10.5
Delay discount exponential model param0.20.21.30.1-0.30.1-0.11.0-0.7-0.1-0.60.2-0.20.2-0.30.1-0.2-0.3-0.20.0-0.00.0-0.50.5-0.5-1.20.3-1.00.2
Delay discount hyperbolic model param0.20.21.30.2-0.40.2-0.21.0-0.8-0.0-0.50.1-0.10.1-0.2-0.1-0.1-0.4-0.30.10.1-0.1-0.40.4-0.4-1.10.3-0.90.1
Fecal boli incidents, locomotor time 10.10.20.3-0.50.5-0.50.5-0.50.50.1-0.50.6-0.60.6-0.5-0.1-0.6-0.1-0.2-0.1-0.20.2-0.40.4-0.10.10.10.10.5
Change in fecal boli incidents, locomotor task0.20.21.4-0.20.4-0.20.2-1.20.9-0.20.6-0.20.2-0.2-0.10.50.40.30.5-0.2-0.50.5-0.60.60.6-0.1-0.20.2-0.2
Time >=10cm from walls, locomotor time 11.31.33.5-0.80.6-0.80.81.1-0.7-1.2-1.71.2-1.21.2-1.11.4-1.90.40.3-0.9-1.31.3-1.01.0-1.5-1.21.3-1.41.2
Bouts of movement, locomotor time 10.40.41.4-0.70.8-0.70.7-1.21.0-0.4-0.30.4-0.40.4-0.50.7-0.00.30.3-0.4-0.90.9-0.80.8-0.2-1.00.2-0.70.3
Total resting periods, locomotor time 10.30.41.4-0.70.7-0.70.7-1.20.9-0.3-0.20.4-0.40.4-0.50.8-0.00.00.1-0.3-0.90.9-0.90.90.0-0.8-0.0-0.50.3
Rest time, locomotor task time 10.30.30.7-0.70.7-0.70.7-0.60.4-0.2-0.50.8-0.80.8-0.70.4-0.6-0.3-0.30.1-0.40.4-0.80.8-0.1-0.2-0.1-0.10.7
Distance moved, locomotor task time 10.60.71.70.9-0.90.9-0.90.3-0.40.60.4-1.11.1-1.11.2-0.61.2-0.3-0.30.60.5-0.51.3-1.30.30.7-0.70.6-1.0
Vertical activity count, locomotor time 10.40.41.10.7-0.70.7-0.70.6-0.60.30.4-0.70.7-0.70.8-0.30.7-0.2-0.20.30.2-0.21.0-1.00.30.5-0.30.5-0.7
Time >=10cm from walls, locomotor time 20.40.42.30.1-0.30.1-0.11.5-1.40.0-0.90.4-0.40.4-0.10.2-0.6-0.8-0.80.4-0.10.10.3-0.3-0.7-0.90.2-0.80.3
Bouts of movement, locomotor time 20.50.51.5-0.80.8-0.80.8-1.21.2-0.5-0.60.4-0.40.4-0.70.5-0.20.40.5-0.5-0.60.6-1.11.1-0.6-1.00.2-0.80.4
Total resting periods, locomotor time 20.90.91.9-1.01.0-1.01.0-1.31.3-0.7-0.90.7-0.70.7-1.00.8-0.60.60.8-0.8-0.90.9-1.41.4-0.9-1.30.5-1.10.7
Rest time, locomotor task time 24.45.19.8-2.62.5-2.62.6-1.81.9-1.7-2.62.5-2.52.5-2.72.2-2.61.00.9-1.6-2.42.4-3.13.1-1.8-1.41.4-1.62.4
Distance moved, locomotor task time 21.01.22.21.3-1.41.3-1.31.4-1.40.80.6-1.11.1-1.11.3-0.81.3-0.9-0.81.01.1-1.11.5-1.50.4-0.1-0.70.1-1.1
Vertical activity count, locomotor time 22.83.15.22.1-2.12.1-2.11.5-1.51.51.8-1.91.9-1.92.0-1.82.3-1.0-0.91.42.0-2.02.2-2.21.20.6-1.20.8-1.8
Weight adjusted by age1.11.21.8-1.31.3-1.31.3-1.11.3-0.9-1.21.2-1.21.2-1.20.7-1.31.00.9-0.9-1.11.1-1.21.2-1.0-0.50.8-0.61.2
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.00.1-0.00.0-0.80.7-0.10.2-0.20.2-0.20.1-0.60.50.40.5-0.10.2-0.20.1-0.1-0.1-0.4-0.1-0.3-0.1
Locomotion in novel chamber0.10.21.10.2-0.30.2-0.21.1-0.9-0.0-0.30.2-0.20.20.10.2-0.5-0.1-0.30.1-0.10.10.7-0.7-0.30.40.20.20.1
Locomotion in novel chamber post-restriction2.63.18.41.7-1.71.7-1.71.1-1.61.92.0-1.81.8-1.81.6-0.81.2-1.7-1.82.01.3-1.31.1-1.12.12.9-2.02.7-1.8
Progressive ratio0.20.21.0-0.00.0-0.00.00.2-0.50.3-0.00.1-0.10.1-0.20.4-0.4-0.7-0.90.7-0.20.2-0.50.50.61.0-0.70.90.0
Food seeking constrained by brief footshock4.85.88.92.6-2.72.6-2.62.3-2.62.61.8-2.22.2-2.22.3-2.42.2-2.5-2.52.73.0-3.02.5-2.51.91.8-2.31.9-2.2
Seeking ratio, punishment vs. effort1.41.83.81.5-1.51.5-1.51.1-1.01.21.1-1.31.3-1.31.6-1.71.6-0.7-0.61.01.9-1.91.9-1.90.40.2-0.70.3-1.3
Run reversals in cocaine runway, females0.40.41.5-0.70.8-0.70.7-1.20.9-0.3-0.60.6-0.60.6-0.40.90.1-0.3-0.1-0.4-0.90.9-0.30.30.0-1.20.2-0.80.5
Run reversals in cocaine runway, males0.10.10.3-0.40.5-0.40.4-0.30.3-0.20.00.4-0.40.4-0.40.5-0.50.30.2-0.3-0.50.5-0.20.20.20.00.20.10.4
Latency to leave start box in cocaine runway0.30.40.8-0.50.4-0.50.50.3-0.0-0.7-0.70.7-0.70.7-0.60.6-0.80.40.4-0.5-0.50.5-0.50.5-0.8-0.80.7-0.90.7
Latency to leave start box in cocaine runway, F1.01.12.7-0.80.7-0.80.80.30.2-1.4-1.11.0-1.01.0-1.01.1-1.21.31.3-1.1-0.60.6-0.70.7-1.6-1.21.4-1.41.1
Latency to leave start box in cocaine runway, M0.20.21.20.1-0.20.1-0.10.3-0.50.50.20.0-0.00.00.0-0.20.1-1.1-1.10.6-0.30.3-0.00.00.80.0-0.50.2-0.1
Cd content in liver2.42.74.5-2.01.9-2.02.0-0.70.9-1.2-1.22.1-2.12.1-2.11.6-1.90.1-0.0-1.0-2.12.1-2.02.00.0-1.31.0-1.12.0
Co content in liver0.30.41.0-0.30.3-0.30.30.6-0.3-0.0-0.81.0-1.01.0-0.6-0.2-0.9-0.6-0.70.1-0.30.3-0.40.4-0.3-1.00.2-0.90.7
Cu content in liver0.10.10.50.1-0.10.1-0.1-0.60.40.60.1-0.20.2-0.20.2-0.70.5-0.4-0.30.20.0-0.00.2-0.20.30.0-0.30.2-0.2
Fe content in liver0.20.31.2-0.30.1-0.30.30.20.1-0.60.10.3-0.30.3-0.60.2-0.50.70.8-0.9-0.30.3-0.80.8-0.3-0.51.1-0.60.5
K content in liver1.01.02.61.2-1.11.2-1.21.1-1.21.20.6-0.80.8-0.81.1-1.00.3-0.8-0.90.71.0-1.01.2-1.20.41.6-0.61.2-1.0
Mg content in liver0.30.31.40.5-0.40.5-0.50.3-0.61.00.2-0.20.2-0.20.4-0.3-0.1-1.1-1.20.80.3-0.30.1-0.10.60.8-0.90.8-0.5
Mn content in liver0.10.11.10.2-0.30.2-0.20.6-0.5-0.10.6-0.20.2-0.20.20.4-0.30.30.2-0.20.2-0.20.3-0.30.21.10.20.7-0.2
Na content in liver0.20.20.90.5-0.50.5-0.50.9-0.40.2-0.30.0-0.00.00.3-0.8-0.40.40.3-0.10.8-0.80.5-0.5-1.00.60.3-0.0-0.2
Rb content in liver1.21.53.8-1.11.0-1.11.10.3-0.0-1.2-0.61.4-1.41.4-1.61.6-1.90.70.6-1.1-1.41.4-1.91.9-0.4-0.91.3-0.91.3
Se content in liver1.41.72.7-1.41.4-1.41.4-1.01.2-1.3-1.61.4-1.41.4-1.40.7-1.61.31.2-1.4-1.31.3-1.31.3-1.6-0.71.5-1.01.3
Sr content in liver0.30.30.70.6-0.60.6-0.60.4-0.50.20.2-0.70.7-0.70.8-0.10.5-0.1-0.1-0.10.4-0.40.8-0.8-0.10.40.10.2-0.7
Zn content in liver0.20.20.7-0.00.3-0.00.0-0.20.2-0.2-0.70.2-0.20.20.3-0.1-0.60.40.3-0.8-0.40.40.5-0.5-0.80.70.60.2-0.2