Hub : Genes

Slc25a45

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000030616 0.44 0.13 0.0e+00 0.26 0.25 0.25 0.23 3.6e-29 7.3e-28 5.5e-28 3.4e-25
2 Adipose mRNA stability ENSRNOG00000030616 0.04 0.03 9.2e-03 0 0.01 0 0 3.1e-01 3.6e-02 1.9e-01 2.6e-01
3 BLA gene expression ENSRNOG00000030616 0.21 0.09 3.1e-12 0.22 0.22 0.21 0.22 6.5e-12 9.0e-12 1.8e-11 3.4e-12
4 Brain gene expression ENSRNOG00000030616 0.23 0.1 0.0e+00 0.23 0.23 0.24 0.23 6.3e-21 1.0e-20 5.1e-22 5.2e-21
5 Brain mRNA stability ENSRNOG00000030616 0.05 0.04 1.9e-03 0.02 0.02 0.01 0.01 6.0e-03 3.8e-03 2.4e-02 1.8e-02
6 IL gene expression ENSRNOG00000030616 0.23 0.12 3.4e-04 0.14 0.14 0.18 0.17 2.7e-04 2.9e-04 4.8e-05 7.9e-05
7 LHb gene expression ENSRNOG00000030616 0.38 0.16 5.4e-07 0.24 0.19 0.19 0.21 2.0e-06 2.5e-05 2.9e-05 8.5e-06
8 Liver gene expression ENSRNOG00000030616 0.09 0.05 3.1e-06 0.04 0.03 0.04 0.03 2.3e-05 7.4e-04 8.1e-05 3.3e-04
9 NAcc gene expression ENSRNOG00000030616 0.22 0.09 5.6e-17 0.21 0.22 0.22 0.21 2.7e-15 1.4e-16 3.4e-16 9.0e-16
10 OFC gene expression ENSRNOG00000030616 0.19 0.1 2.1e-04 0.12 0.13 0.13 0.13 8.2e-04 5.0e-04 5.7e-04 4.6e-04
11 PL gene expression ENSRNOG00000030616 0.24 0.09 0.0e+00 0.3 0.29 0.28 0.3 2.3e-23 4.4e-22 1.0e-21 4.8e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail2.99.520.2-2.3-3.5-3.2-2.9-3.9-4.5-2.9-2.6-1.9-2.7-2.9
BMI without tail1.53.26.1-1.6-1.4-1.7-2.0-2.3-2.5-1.6-1.9-0.9-1.6-1.6
Body weight3.916.519.3-3.7-3.9-4.4-3.9-4.2-4.4-4.2-3.9-3.7-4.1-4.2
Epididymis fat weight2.76.38.32.91.52.72.82.62.02.52.72.52.72.5
Glucose1.82.83.91.90.91.71.91.41.01.71.82.01.81.7
Heart weight3.75.36.82.32.32.42.42.12.02.41.92.62.42.4
Left kidney weight0.61.82.71.40.51.31.61.41.11.41.61.11.31.4
Right kidney weight0.20.51.40.7-0.60.50.91.10.60.51.2-0.10.60.5
Tail length0.61.93.3-1.7-0.2-1.4-1.4-0.9-0.3-1.5-1.8-1.6-1.6-1.5
Length with tail2.07.210.0-2.7-2.1-3.0-2.5-2.2-1.9-3.0-2.9-3.2-3.0-3.0
Length without tail2.14.66.5-1.8-2.1-2.5-1.8-1.9-1.8-2.3-2.0-2.5-2.3-2.3
Liver weight, left0.00.10.20.50.10.20.30.30.20.20.20.20.20.2
Liver weight, right0.10.20.80.40.60.30.90.50.50.3-0.20.40.30.3
Parametrial fat weight2.03.95.42.30.92.02.01.71.12.22.32.32.22.2
Retroperitoneal fat weight5.719.023.44.83.04.54.74.33.64.64.54.44.64.6
Intraocular pressure0.91.33.40.60.11.11.11.71.41.01.80.31.21.0
Extensor digitorum longus weight8.132.435.5-5.7-5.1-6.0-5.8-5.8-5.6-5.9-5.4-5.5-5.9-5.9
Soleus weight4.312.714.63.63.03.73.83.63.33.73.33.63.73.7
Tibialis anterior weight11.037.845.0-6.4-5.7-6.6-5.6-5.5-5.4-6.6-5.9-6.7-6.6-6.6
Tibia length1.23.49.5-1.6-3.1-1.8-1.2-0.9-1.5-1.8-0.6-2.6-1.8-1.8
Number of licking bursts0.30.40.7-0.5-0.8-0.6-0.8-0.6-0.7-0.5-0.3-0.7-0.5-0.5
Food consumed during 24 hour testing period0.10.10.4-0.2-0.5-0.20.10.20.2-0.20.2-0.6-0.2-0.2
Times rat made contact with spout0.60.71.6-0.8-0.0-0.7-1.2-1.2-0.7-0.7-1.0-0.4-0.8-0.7
Mean time between licks in bursts0.50.72.2-0.80.5-0.9-0.9-0.8-0.2-0.7-1.5-0.5-0.8-0.7
Mean num. licks in bursts0.20.20.90.31.00.50.30.10.50.40.00.70.40.4
Std. dev. time between licks in bursts0.30.31.80.31.40.2-0.00.30.80.3-0.40.50.20.3
Water consumed over 24 hours0.91.12.3-1.1-0.4-1.0-1.5-1.2-0.7-1.1-1.1-1.0-1.1-1.1
Indifference point 0 sec0.00.10.10.20.10.20.30.10.00.30.10.30.10.3
Indifference point AUC3.84.45.7-2.1-2.3-2.3-2.1-1.9-1.9-2.2-1.6-2.4-2.1-2.2
Indifference point function ln k9.213.116.63.44.13.83.63.33.53.82.64.03.63.8
Indifference point function log k9.213.116.63.44.13.83.63.33.53.82.64.03.63.8
Delay discounting total patch changes 0 sec0.00.00.20.10.40.10.20.10.20.3-0.10.20.10.3
Delay discounting total patch changes 12 sec5.06.68.0-2.5-2.4-2.8-2.8-2.8-2.6-2.5-2.2-2.5-2.6-2.5
Delay discounting total patch changes 18 sec0.70.91.5-1.0-1.2-1.0-0.8-0.9-1.2-0.9-0.5-0.9-0.9-0.9
Delay discounting total patch changes 24 sec2.53.14.1-2.0-1.5-2.0-1.6-1.5-1.3-1.8-1.7-2.0-1.9-1.8
Delay discounting total patch changes 6 sec0.81.31.8-1.0-0.8-1.3-1.1-1.3-1.2-1.1-1.3-1.0-1.2-1.1
Delay discounting time to switch 0 sec2.13.37.1-1.1-2.4-1.8-1.8-2.1-2.7-1.6-1.1-1.4-1.6-1.6
Delay discounting water rate 0 sec4.87.613.01.92.82.63.13.23.62.62.42.22.72.6
Delay discounting water rate 12 sec9.714.521.82.94.74.03.94.14.73.62.73.63.63.6
Delay discounting water rate 18 sec3.95.28.01.72.82.32.62.42.72.21.32.32.22.2
Delay discounting water rate 24 sec4.86.610.11.82.92.72.83.03.22.32.12.42.52.3
Delay discounting water rate 6 sec4.87.011.61.73.42.72.72.93.42.41.82.52.62.4
Locomotor activity2.43.86.91.52.62.01.52.12.61.81.21.81.91.8
Locomotor testing distance3.35.511.61.83.42.41.82.43.12.11.22.32.32.1
Locomotor testing rearing2.64.18.21.72.92.21.62.02.51.91.12.11.91.9
Light reinforcement 10.10.20.60.50.80.40.20.50.60.50.30.40.40.5
Light reinforcement 21.01.32.81.3-0.21.21.71.50.81.01.60.51.01.0
Reaction time number correct0.30.40.8-0.8-0.3-0.6-0.2-0.2-0.2-0.9-0.7-0.9-0.8-0.9
Reaction time mean minus median3.85.08.3-2.1-2.9-2.2-2.2-2.0-2.6-2.1-1.4-2.5-2.3-2.1
Reaction time mean minus median AUC2.02.53.9-1.6-2.0-1.6-1.5-1.3-1.6-1.5-1.1-1.9-1.7-1.5
Reaction time num false alarms0.50.62.90.51.70.50.50.40.90.8-0.31.00.50.8
Reaction time num false alarms AUC0.10.21.2-0.11.1-0.2-0.2-0.30.20.1-0.90.3-0.10.1
Reaction time trials correct on left0.30.40.8-0.8-0.3-0.6-0.2-0.2-0.2-0.9-0.7-0.9-0.8-0.9
Reaction time trials on left0.40.61.0-0.9-0.4-0.7-0.3-0.3-0.2-1.0-0.8-1.0-0.9-1.0
Reaction time mean0.10.20.8-0.3-0.9-0.4-0.3-0.3-0.6-0.30.3-0.5-0.3-0.3
Reaction time mean AUC0.10.20.9-0.3-1.0-0.3-0.3-0.3-0.6-0.20.4-0.4-0.3-0.2
Median of all reaction times0.00.10.40.2-0.40.00.10.0-0.20.20.60.00.10.2
Reaction time omissions1.62.23.2-1.8-1.3-1.3-1.6-1.6-1.5-1.5-1.1-1.4-1.5-1.5
Reaction time false alarm rate0.40.51.90.71.40.50.30.30.60.8-0.21.00.50.8
Reaction time premature initiation rate2.63.46.6-2.2-0.3-1.9-2.0-1.9-1.3-1.8-2.6-1.6-2.0-1.8
Reaction time premature initiations4.05.69.2-2.9-0.7-2.5-2.5-2.2-1.5-2.5-3.0-2.3-2.6-2.5
Std. dev. reaction times1.21.63.1-1.2-1.8-1.2-1.2-1.1-1.4-1.2-0.6-1.5-1.3-1.2
Reaction time trials completed0.40.61.0-0.9-0.4-0.7-0.3-0.3-0.2-1.0-0.8-1.0-0.9-1.0
Reaction time trials AUC0.20.30.6-0.7-0.2-0.5-0.1-0.2-0.1-0.8-0.7-0.7-0.6-0.8
Social response proportion1.01.11.6-0.8-1.3-1.1-1.1-1.0-1.1-1.0-0.9-1.2-1.0-1.0
Social responses0.20.30.5-0.3-0.3-0.6-0.6-0.3-0.2-0.5-0.7-0.7-0.6-0.5
Social time0.40.50.7-0.5-0.2-0.6-0.8-0.4-0.3-0.9-0.9-0.8-0.9-0.9
Conditioned locomotion1.61.92.5-1.6-1.1-1.5-1.1-1.2-1.1-1.5-1.5-1.4-1.5-1.5
Cocaine response after cond. corrected1.82.03.31.31.81.41.61.31.41.40.71.61.41.4
Cocaine response after cond. not corrected1.41.52.41.11.61.21.31.21.21.20.61.41.21.2
Cocaine response before conditioning0.81.01.7-1.1-1.3-1.0-1.2-0.8-1.0-0.9-0.5-1.1-0.9-0.9
Saline control response4.05.46.7-2.4-1.7-2.6-2.3-2.3-2.0-2.4-2.5-2.3-2.4-2.4
Condit. Reinf. active minus inactive responses0.10.20.80.0-0.40.40.40.40.00.40.90.20.40.4
Condit. Reinf. active-inactive response ratio0.80.82.40.5-0.60.81.11.10.30.91.50.50.90.9
Condit. Reinf. active responses0.10.10.3-0.3-0.6-0.2-0.4-0.4-0.6-0.20.2-0.2-0.1-0.2
Condit. Reinf. inactive responses0.50.61.5-0.40.1-0.6-1.1-1.2-0.8-0.7-0.9-0.2-0.6-0.7
Condit. Reinf. lever presses2.43.26.1-1.7-2.5-1.9-1.6-1.5-1.9-1.8-0.9-2.1-1.7-1.8
Condit. Reinf. lever reinforcers received0.30.50.9-0.8-0.9-0.5-0.8-0.7-0.8-0.6-0.1-0.6-0.5-0.6
Pavlov. Cond. lever latency0.60.82.20.61.50.90.50.61.00.90.21.10.80.9
Pavlov. Cond. magazine entry latency4.14.76.1-1.9-2.1-2.1-2.5-2.4-2.5-2.1-1.8-2.0-2.2-2.1
Pavlov. Cond. change in total contacts2.43.47.9-1.6-2.8-1.7-1.7-1.7-2.2-1.7-0.5-2.0-1.7-1.7
Pavlov. Cond. index score2.83.66.3-1.6-2.5-1.9-1.8-1.8-2.2-1.9-1.1-2.0-1.9-1.9
Pavlov. Cond. latency score2.32.95.5-1.3-2.3-1.7-1.6-1.6-2.0-1.7-0.9-1.8-1.7-1.7
Pavlov. Cond. lever contacts0.50.71.8-0.6-1.4-0.9-0.4-0.4-0.8-0.9-0.3-1.2-0.9-0.9
Pavlov. Cond. magazine entry number7.49.110.72.83.23.03.33.23.23.02.33.03.03.0
Pavlov. Cond. intertrial magazine entries1.31.72.41.21.01.41.61.51.21.31.21.21.31.3
Pavlov. Cond. lever-magazine prob. diff.3.44.46.7-1.8-2.6-2.1-2.0-2.1-2.4-2.1-1.3-2.2-2.1-2.1
Pavlov. Cond. response bias2.02.84.6-1.4-2.1-1.7-1.5-1.4-1.8-1.7-1.0-1.9-1.7-1.7
Conditioned reinforcement - actives0.30.30.90.3-0.40.50.70.90.50.60.8-0.10.50.6
Conditioned reinforcement - inactives6.47.310.12.61.52.82.73.02.62.93.22.32.82.9
Conditioned locomotion9.010.814.02.92.53.33.53.73.43.43.52.83.43.4
Intermittent access intake day 1-15 change0.80.81.90.50.20.90.91.41.11.01.20.30.91.0
Intermittent access intake escalation0.70.71.40.40.20.80.91.20.90.91.10.40.90.9
Intermittent access intake escalation 20.20.20.7-0.2-0.10.40.40.80.70.50.8-0.10.40.5
Intermitt. access day 1 inactive lever presses2.52.74.52.11.11.81.21.61.41.61.81.61.71.6
Intermitt. access day 15 inactive lever presses2.83.14.92.20.71.81.72.01.61.82.21.41.81.8
Intermitt. access escalation Index3.53.15.32.02.01.82.01.21.31.71.32.31.81.7
Intermittent access day 1 total infusions5.56.28.32.91.22.52.82.21.42.72.72.82.62.7
Intermittent access day 15 total infusions8.89.812.83.01.63.23.53.42.63.43.62.93.33.4
Intermittent access terminal intake (last 3 days)6.06.69.42.60.82.63.02.91.92.83.12.32.72.8
Intermittent access total infusions4.85.47.62.40.82.32.72.41.42.52.82.42.52.5
Intermittent access day 1 locomotion3.94.06.72.41.42.02.11.61.12.11.92.62.12.1
Intermittent access day 15 total locomotion5.25.67.92.11.12.52.52.51.92.62.82.32.62.6
Intermittent access total locomotion6.16.910.02.81.02.73.02.61.62.83.22.82.82.8
Intermittent access standard deviation1.31.42.51.10.61.20.91.61.31.21.40.81.21.2
Cocaine induced anxiety0.00.00.3-0.1-0.50.10.20.3-0.0-0.00.1-0.3-0.1-0.0
Post-drug Anxiety1.31.43.1-1.3-1.7-1.2-0.7-0.6-0.8-1.2-0.9-1.7-1.2-1.2
Baseline Anxiety2.32.53.3-1.5-1.1-1.8-1.8-1.4-1.2-1.6-1.7-1.7-1.6-1.6
Lifetime Intake4.14.66.22.20.92.22.52.11.32.42.52.32.32.4
Incentive Sensitization - Responses0.60.61.20.7-0.10.51.00.80.40.91.10.50.80.9
Incentive Sensitization - Breakpoint0.90.91.70.80.00.71.21.00.61.11.30.71.01.1
Progressive ratio test 1 active lever presses3.33.44.11.91.21.91.91.91.62.02.01.81.92.0
Progressive ratio test 1 breakpoint3.03.13.71.71.21.81.91.91.61.91.91.61.81.9
Progressive ratio test 1 inactive lever presses1.31.42.01.41.21.20.81.01.01.31.11.41.31.3
Progressive ratio test 2 active lever presses4.95.27.52.11.02.12.62.51.92.52.72.02.42.5
Progressive ratio test 2 breakpoint6.37.09.02.41.62.53.03.02.52.83.02.32.82.8
Progressive ratio test 2 inactive lever presses9.010.414.13.41.83.23.33.32.63.53.83.13.43.5
Total sessions with >9 infusions1.92.13.21.61.11.41.61.30.91.51.41.81.61.5
Short access day 1 total inactive lever presses3.94.45.62.01.82.12.02.01.92.12.22.42.32.1
Short access day 10 total inactive lever presses4.14.56.22.32.52.21.71.92.22.11.72.42.22.1
Short access day 1 total infusions2.72.94.91.91.11.71.91.30.81.81.72.21.81.8
Short access day 10 total infusions1.51.63.11.50.21.31.50.80.11.41.41.71.41.4
Short access total infusions1.31.52.71.30.71.21.50.90.41.31.21.71.31.3
Short access day 1 locomotion2.52.64.51.41.21.71.71.30.91.81.52.11.71.8
Short access day 10 total locomotion1.61.83.31.50.91.51.51.00.61.31.41.81.51.3
Short access total locomotion1.31.42.91.20.91.21.20.80.51.21.11.71.31.2
Compulsive drug intake2.72.74.7-1.4-0.0-1.7-2.0-1.9-1.0-1.8-2.2-1.4-1.7-1.8
One hour access (0.3 mA shock)11.213.116.13.42.43.73.94.03.43.83.93.43.83.8
One hour access (shock baseline)9.611.116.32.91.43.43.73.92.93.64.02.93.53.6
Number of responses in last shaping day1.51.52.40.81.51.31.01.31.51.21.01.31.21.2
Context. condit. distance diff. score2.22.63.51.81.71.61.91.31.41.71.21.81.61.7
Locomotion velocity, session 10.10.10.3-0.30.6-0.00.10.00.3-0.1-0.60.0-0.1-0.1
Locomotion distance, session 10.50.71.5-0.6-0.4-0.7-0.8-1.2-1.1-0.8-1.0-0.3-0.8-0.8
Locomotion velocity, session 23.13.64.7-1.6-1.7-1.8-2.0-2.1-2.2-2.0-1.9-1.6-1.9-2.0
Locomotion distance, session 20.71.02.2-0.7-0.5-0.9-1.1-1.5-1.3-1.0-1.3-0.5-1.0-1.0
Locomotion velocity, session 30.20.20.60.60.20.40.70.1-0.10.40.20.80.50.4
Locomotion distance, session 30.10.10.20.20.30.20.40.20.20.20.10.30.30.2
Stereotopy head waving bouts, day 30.50.61.40.90.70.71.20.60.30.80.31.20.80.8
Stereotopy head waving duration, day 30.60.71.20.90.71.01.00.80.50.90.71.10.90.9
Locomotion velocity, session 70.50.51.20.90.20.71.00.0-0.30.70.61.10.70.7
Locomotion distance, session 70.10.20.60.40.60.20.6-0.3-0.10.3-0.20.70.30.3
Stereotopy head waving bouts, day 70.10.20.60.3-0.50.40.40.3-0.30.40.80.20.30.4
Stereotopy head waving duration, day 71.21.53.0-1.0-1.7-1.1-1.3-1.3-1.7-1.1-0.6-1.1-1.2-1.1
Locomotion velocity, session 80.70.92.1-0.7-0.2-1.1-0.7-0.8-0.5-1.1-1.5-0.9-1.0-1.1
Locomotion distance, session 80.20.31.00.70.20.51.00.3-0.00.50.30.80.50.5
Degree of sensitization distance0.10.10.20.30.0-0.10.4-0.2-0.30.1-0.20.40.10.1
Degree of sensitization stereotypy0.70.82.3-0.7-1.5-0.7-0.8-0.8-1.2-0.7-0.1-0.9-0.8-0.7
Condit. Reinf. active minus inactive responses0.20.30.7-0.6-0.2-0.5-0.8-0.7-0.6-0.4-0.5-0.2-0.4-0.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.40.1-0.1-0.7-0.4-0.2-0.1-0.2-0.0-0.1-0.1
Condit. Reinf. active responses0.10.10.2-0.2-0.4-0.3-0.3-0.4-0.4-0.1-0.00.0-0.1-0.1
Condit. Reinf. inactive responses0.10.20.50.5-0.50.00.70.2-0.10.30.50.30.30.3
Incentive salience index mean0.40.50.9-0.7-0.5-0.6-0.9-0.9-0.9-0.5-0.6-0.3-0.5-0.5
Condit. Reinf. lever presses0.30.51.1-0.6-1.0-0.8-0.6-0.6-0.8-0.6-0.4-0.6-0.6-0.6
Time in familiar zone, hab. session 10.30.20.50.70.20.40.40.40.20.60.50.60.50.6
Time in novel zone, hab. session 10.30.31.30.21.10.40.50.51.00.3-0.10.40.40.3
Total zone transitions, hab. session 10.81.11.7-1.2-0.9-1.0-1.2-1.3-1.2-1.0-0.9-0.9-1.0-1.0
Total locomotion distance, hab. session 10.20.30.70.50.20.60.80.3-0.00.60.50.80.60.6
Locomotion velocity, hab. session 10.00.00.20.0-0.20.10.3-0.2-0.40.10.10.30.10.1
Time in familiar zone, hab. session 20.20.21.10.31.10.00.40.40.80.2-0.50.30.20.2
Time in novel zone, hab. session 20.30.30.8-0.5-0.7-0.2-0.8-0.7-0.9-0.40.0-0.2-0.3-0.4
Total zone transitions, hab. session 21.72.34.4-1.2-1.3-1.3-1.5-2.1-2.1-1.4-1.4-0.8-1.4-1.4
Total locomotion distance, hab. session 20.10.10.70.2-0.10.00.1-0.6-0.8-0.0-0.20.60.0-0.0
Locomotion velocity, hab. session 20.10.10.50.4-0.20.20.5-0.3-0.70.20.10.70.20.2
Novel to familiar place preference ratio1.61.74.0-1.2-2.0-1.2-1.4-1.1-1.5-1.2-0.3-1.4-1.2-1.2
Novelty place preference0.80.92.4-0.8-1.5-0.8-1.1-0.8-1.1-0.8-0.0-1.0-0.8-0.8
Time in novel zone, NPP test0.60.61.7-0.6-1.3-0.6-1.0-0.7-0.9-0.7-0.0-0.8-0.7-0.7
Total zone transitions, NPP test2.73.94.9-1.8-1.8-1.9-2.2-2.2-2.2-2.0-1.8-1.7-2.0-2.0
Total locomotion distance, NPP test0.10.20.6-0.1-0.3-0.3-0.3-0.7-0.8-0.3-0.40.1-0.3-0.3
Locomotion velocity, NPP test0.20.20.8-0.3-0.4-0.3-0.5-0.8-0.9-0.4-0.4-0.0-0.3-0.4
Pavlov. Cond. lever latency0.30.40.70.60.80.60.80.70.70.60.50.50.60.6
Pavlov. Cond. magazine entry latency0.40.51.2-0.6-0.9-0.5-0.9-1.0-1.1-0.5-0.2-0.3-0.5-0.5
Pavlov. Cond. change in total contacts0.30.31.2-0.4-1.1-0.2-0.8-0.5-0.7-0.20.4-0.3-0.2-0.2
Pavlov. Cond. index score0.20.30.6-0.6-0.8-0.5-0.7-0.6-0.5-0.4-0.2-0.5-0.5-0.4
Pavlov. Cond. latency score0.10.10.3-0.3-0.5-0.3-0.6-0.5-0.5-0.3-0.2-0.2-0.3-0.3
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.2-0.1-0.3-0.3-0.2-0.1-0.20.0-0.1-0.1
Pavlov. Cond. magazine entry number0.40.51.00.71.00.60.80.60.60.60.10.80.60.6
Pavlov. Cond. intertrial magazine entries0.60.81.30.60.50.80.81.01.10.91.20.60.90.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.0-0.8-1.0-0.7-0.9-0.9-0.8-0.7-0.4-0.7-0.7-0.7
Pavlov. Cond. response bias0.20.20.4-0.6-0.6-0.3-0.6-0.4-0.3-0.3-0.0-0.5-0.4-0.3
Bone: apparent density0.40.72.30.1-1.3-0.7-0.5-1.1-1.5-0.6-0.5-0.4-0.7-0.6
Bone surface4.47.814.1-2.2-3.8-2.9-2.4-2.6-3.3-2.8-1.9-2.9-2.8-2.8
Bone volume1.72.87.7-0.9-2.8-1.6-1.3-1.5-2.3-1.5-0.8-1.6-1.6-1.5
Bone: connectivity density2.23.56.3-1.1-2.2-1.9-1.6-2.1-2.5-1.8-1.6-1.6-1.9-1.8
Bone: cortical apparent density0.40.51.3-1.0-0.0-0.6-1.1-0.9-0.4-0.6-0.6-0.5-0.6-0.6
Bone: cortical area0.60.92.1-0.7-1.5-1.0-0.7-0.6-0.9-1.0-0.6-1.3-1.0-1.0
Bone: cortical porosity0.20.20.6-0.1-0.4-0.3-0.6-0.6-0.8-0.3-0.3-0.1-0.3-0.3
Bone: cortical porosity0.70.81.4-0.6-0.8-0.9-1.1-1.1-1.2-0.8-0.9-0.7-0.9-0.8
Bone: cortical thickness2.43.95.1-2.0-1.2-2.1-2.1-1.9-1.3-2.2-2.3-2.2-2.2-2.2
Bone: cortical thickness0.50.51.5-0.80.4-0.7-0.8-0.70.1-0.8-1.2-0.6-0.7-0.8
Bone: cortical tissue density0.50.61.6-1.1-0.1-0.7-1.2-1.0-0.5-0.7-0.8-0.6-0.7-0.7
Bone: elastic displacement1.61.84.50.92.11.31.31.52.01.10.51.11.11.1
Bone: elastic work0.50.72.1-0.90.4-0.8-0.8-0.70.0-0.9-1.4-0.7-0.9-0.9
Bone: endosteal estimation0.81.73.11.8-0.11.31.71.20.31.31.51.41.31.3
Bone: endosteal perimeter1.12.24.21.9-0.51.52.01.50.31.52.01.31.41.5
Bone: final force3.15.06.2-1.9-2.5-2.4-2.0-2.1-2.3-2.4-2.0-2.3-2.3-2.4
Bone: final moment2.74.45.5-1.8-2.3-2.3-1.9-1.9-2.2-2.2-1.9-2.2-2.2-2.2
Bone: marrow area0.81.83.21.80.01.41.71.20.31.41.51.51.31.4
Bone: maximum diameter0.30.52.6-0.2-1.6-0.50.10.2-0.6-0.60.2-1.0-0.6-0.6
Bone: maximum force3.66.310.6-2.0-3.3-2.6-2.2-2.5-3.0-2.5-1.8-2.4-2.5-2.5
Bone: maximum moment3.15.39.0-1.8-3.0-2.4-2.0-2.3-2.8-2.3-1.7-2.2-2.3-2.3
Bone: minimum diameter0.71.22.51.6-0.11.21.10.6-0.11.21.31.41.11.2
Bone: periosteal estimation0.10.31.30.6-1.10.20.60.4-0.50.10.6-0.10.10.1
Bone: periosteal perimeter0.20.31.70.1-1.3-0.30.1-0.0-0.7-0.30.2-0.5-0.3-0.3
Bone: post-yield work1.31.88.1-0.1-2.8-0.9-0.5-1.4-2.7-0.60.4-0.4-0.6-0.6
Bone: stiffness3.25.08.9-1.8-3.0-2.3-2.1-2.3-2.8-2.2-1.5-2.1-2.1-2.2
Bone: tissue strength0.10.10.3-0.1-0.6-0.2-0.0-0.1-0.4-0.10.2-0.3-0.1-0.1
Bone: trabecular number0.50.83.0-0.1-1.7-0.8-0.3-1.0-1.5-0.7-0.3-0.8-0.8-0.7
Bone: trabecular spacing0.30.41.70.01.30.50.20.30.70.50.00.70.50.5
Bone: trabecular thickness0.50.61.91.40.20.90.70.40.20.90.90.90.70.9
Bone: trabecular tissue density3.85.36.22.41.82.32.32.52.32.42.42.12.42.4
Breakpoint value in progressive ratio session3.33.74.6-1.6-2.1-2.0-1.9-1.9-2.0-1.9-1.6-2.1-1.9-1.9
Distance traveled before self-admin0.80.91.9-0.7-1.4-1.0-1.1-0.7-1.0-0.9-0.5-1.1-0.9-0.9
Distance traveled after self-admin0.30.30.6-0.4-0.8-0.5-0.7-0.4-0.5-0.5-0.2-0.7-0.5-0.5
Delta time in closed arm before/after self-admin0.20.21.3-0.11.1-0.0-0.3-0.20.3-0.0-0.90.4-0.1-0.0
Delta time in open arm before/after self-admin0.20.21.0-0.0-1.0-0.3-0.2-0.0-0.3-0.20.4-0.7-0.3-0.2
Diff in mean of infusions in LGA sessions0.30.40.7-0.8-0.5-0.5-0.6-0.4-0.3-0.6-0.5-0.8-0.6-0.6
Extinction: sum of active levers before priming5.25.37.5-1.8-2.3-2.3-2.4-2.7-2.7-2.2-2.1-2.1-2.3-2.2
Active lever presses in extinction session 62.62.54.7-1.4-2.0-1.6-1.3-0.9-1.3-1.7-1.2-2.2-1.8-1.7
Delta distance traveled before/after self-admin0.10.10.40.20.70.30.20.20.50.20.00.30.30.2
Delta ambulatory time before/after self-admin0.10.10.6-0.00.80.2-0.00.10.50.1-0.20.20.20.1
Time in closed arm before self-admin0.10.20.90.2-0.9-0.3-0.1-0.1-0.5-0.20.3-0.4-0.2-0.2
Time in closed arm after self-admin0.10.10.20.40.50.2-0.10.10.20.3-0.10.50.30.3
Time in open arm before self-admin0.91.04.80.02.20.90.70.21.00.8-0.11.40.80.8
Time in open arm after self-admin0.20.20.70.00.80.40.50.40.70.40.20.30.30.4
Sum of active levers in priming session hrs 5-61.81.84.5-1.6-2.1-1.2-1.1-0.3-0.7-1.2-0.4-2.1-1.3-1.2
Time to tail flick, vehicle, before self-admin0.70.71.5-0.9-1.1-0.8-0.6-0.8-1.2-0.7-0.7-0.7-0.9-0.7
Time to tail flick, vehicle, after self-admin1.51.62.6-1.1-0.7-1.2-1.2-1.5-1.5-1.3-1.6-0.7-1.2-1.3
Time to tail flick, test, before self-admin0.70.71.91.10.90.70.90.40.30.80.51.40.90.8
Time to tail flick, test, after self-admin0.10.10.9-0.9-0.0-0.1-0.10.00.1-0.2-0.1-0.2-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.5-0.1-0.6-0.8-0.9-0.6-0.7-0.9-0.3-0.5-0.7
Delta time to tail flick, test, before/after SA1.61.44.2-2.0-0.9-1.0-1.0-0.5-0.3-1.2-0.9-1.8-1.3-1.2
Ambulatory time before self-admin0.60.62.6-0.4-1.6-0.8-0.7-0.4-0.9-0.7-0.1-1.0-0.7-0.7
Ambulatory time after self-admin0.10.10.40.4-0.60.2-0.00.1-0.30.30.70.10.30.3
Total heroin consumption6.27.58.4-2.9-2.4-2.8-2.9-2.8-2.7-2.8-2.5-2.7-2.7-2.8
Area under the delay curve0.10.10.3-0.10.40.3-0.4-0.4-0.30.1-0.10.60.10.1
Delay disc. indifference point, 0s delay0.30.31.20.60.90.60.30.00.10.5-0.11.10.50.5
Delay disc. indifference point, 16s delay0.80.81.50.90.51.10.50.50.51.01.21.11.01.0
Delay disc. indifference point, 2s delay0.10.10.1-0.00.10.30.30.30.10.30.20.40.30.3
Delay disc. indifference point, 24s delay0.20.21.0-0.21.00.5-0.30.00.40.3-0.20.40.20.3
Delay disc. indifference point, 4s delay0.20.20.90.21.00.5-0.2-0.10.20.3-0.30.80.30.3
Delay disc. indifference point, 8s delay0.10.10.50.10.70.3-0.3-0.3-0.0-0.0-0.40.50.1-0.0
Delay discount exponential model param0.10.10.20.2-0.4-0.30.50.40.2-0.10.2-0.5-0.1-0.1
Delay discount hyperbolic model param0.10.10.20.3-0.3-0.20.50.40.2-0.00.2-0.4-0.0-0.0
Fecal boli incidents, locomotor time 10.30.32.1-0.2-1.4-0.20.20.2-0.5-0.20.5-0.7-0.3-0.2
Change in fecal boli incidents, locomotor task0.20.20.70.60.90.1-0.2-0.30.1-0.0-0.70.50.1-0.0
Time >=10cm from walls, locomotor time 10.70.71.71.1-0.80.61.00.8-0.20.81.30.70.70.8
Bouts of movement, locomotor time 11.82.03.3-1.8-1.1-1.3-1.5-1.6-1.1-1.5-0.9-1.5-1.3-1.5
Total resting periods, locomotor time 11.31.52.6-1.6-1.1-1.1-1.2-1.4-1.1-1.3-0.6-1.3-1.1-1.3
Rest time, locomotor task time 11.41.62.51.10.91.31.51.61.51.11.30.91.21.1
Distance moved, locomotor task time 10.10.10.6-0.2-0.3-0.3-0.3-0.6-0.7-0.2-0.30.0-0.3-0.2
Vertical activity count, locomotor time 11.51.61.81.11.21.31.21.21.21.31.21.31.31.3
Time >=10cm from walls, locomotor time 20.20.20.8-0.1-0.9-0.3-0.2-0.3-0.6-0.30.2-0.4-0.4-0.3
Bouts of movement, locomotor time 20.60.61.3-0.8-0.6-0.7-1.1-1.1-0.7-0.7-0.6-0.7-0.7-0.7
Total resting periods, locomotor time 20.30.30.8-0.4-0.5-0.5-0.9-0.9-0.6-0.5-0.3-0.4-0.4-0.5
Rest time, locomotor task time 22.42.84.82.21.31.91.31.81.51.61.61.71.71.6
Distance moved, locomotor task time 21.21.42.2-1.5-0.9-1.2-1.0-1.2-1.0-1.2-1.1-1.2-1.2-1.2
Vertical activity count, locomotor time 20.20.21.0-0.31.00.10.40.51.00.2-0.20.00.20.2
Weight adjusted by age2.62.95.1-2.3-1.8-1.5-1.6-1.4-1.5-1.8-1.4-1.9-1.7-1.8
Seeking ratio, delayed vs. immediate footshock0.10.10.20.20.30.10.1-0.4-0.10.10.20.50.30.1
Locomotion in novel chamber4.75.98.42.51.12.42.72.92.22.42.92.12.52.4
Locomotion in novel chamber post-restriction3.44.05.62.41.42.01.92.11.92.12.21.92.12.1
Progressive ratio2.83.36.5-1.1-2.1-1.8-1.6-2.2-2.6-1.8-1.4-1.3-1.8-1.8
Food seeking constrained by brief footshock0.10.20.40.10.4-0.3-0.7-0.40.1-0.4-0.7-0.2-0.3-0.4
Seeking ratio, punishment vs. effort2.63.26.91.32.61.71.41.82.51.71.01.61.71.7
Run reversals in cocaine runway, females0.60.61.7-0.40.1-0.6-0.9-1.3-1.2-0.6-1.10.2-0.6-0.6
Run reversals in cocaine runway, males0.60.61.80.60.80.60.51.21.40.50.50.20.60.5
Latency to leave start box in cocaine runway0.10.10.40.6-0.30.20.2-0.2-0.50.30.30.40.20.3
Latency to leave start box in cocaine runway, F0.10.10.30.0-0.3-0.0-0.1-0.5-0.5-0.00.10.1-0.0-0.0
Latency to leave start box in cocaine runway, M0.10.10.50.7-0.20.20.20.3-0.00.30.10.10.10.3
Cd content in liver1.51.62.91.20.51.21.51.71.31.21.60.71.21.2
Co content in liver1.72.06.20.92.51.40.91.22.01.30.61.41.31.3
Cu content in liver0.30.41.0-0.2-0.5-0.5-0.9-1.0-0.8-0.6-0.6-0.4-0.6-0.6
Fe content in liver0.10.10.4-0.5-0.6-0.40.00.0-0.2-0.4-0.1-0.6-0.4-0.4
K content in liver1.71.73.0-1.0-1.4-1.3-1.2-1.6-1.7-1.3-1.3-0.9-1.3-1.3
Mg content in liver0.30.31.3-0.1-0.6-0.3-0.6-1.0-1.1-0.3-0.30.2-0.2-0.3
Mn content in liver2.83.24.9-1.8-2.2-1.8-1.7-1.5-1.7-1.8-1.2-2.0-1.8-1.8
Na content in liver1.21.32.1-1.2-1.4-1.2-0.9-0.7-0.9-1.2-1.0-1.4-1.3-1.2
Rb content in liver1.41.83.01.61.21.41.10.80.91.51.21.71.51.5
Se content in liver0.20.21.30.4-1.20.00.30.2-0.30.00.8-0.30.00.0
Sr content in liver3.53.24.7-2.0-1.5-1.9-1.8-1.4-1.2-1.9-1.6-2.2-1.9-1.9
Zn content in liver1.31.42.3-1.0-1.1-1.2-1.2-1.5-1.4-1.2-1.0-1.1-1.2-1.2