Hub : Genes

Gzmm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000030530 0.25 0.12 0.0e+00 0.3 0.34 0.33 0.34 1.4e-16 5.9e-19 2.7e-18 1.3e-18
2 BLA mRNA stability ENSRNOG00000030530 0.14 0.09 1.1e-08 0.15 0.14 0.13 0.14 2.8e-08 9.4e-08 1.9e-07 6.7e-08
3 Brain gene expression ENSRNOG00000030530 0.17 0.09 0.0e+00 0.21 0.21 0.21 0.21 1.7e-19 2.6e-19 5.7e-19 6.7e-19
4 IL gene expression ENSRNOG00000030530 0.16 0.11 1.6e-03 0.08 0.08 0.08 0.07 6.4e-03 6.0e-03 5.4e-03 1.1e-02
5 NAcc gene expression ENSRNOG00000030530 0.07 0.05 4.4e-05 0.05 0.05 0.06 0.05 2.2e-04 1.1e-04 6.1e-05 1.5e-04
6 NAcc isoform ratio ENSRNOT00000011086 0.04 0.04 2.3e-03 0.03 0.03 0.03 0.03 2.3e-03 2.0e-03 4.3e-03 4.3e-03
7 NAcc isoform ratio ENSRNOT00000095743 0.03 0.03 4.4e-03 0.03 0.03 0.03 0.03 3.3e-03 3.3e-03 5.0e-03 5.0e-03
8 OFC gene expression ENSRNOG00000030530 0.31 0.19 1.8e-05 0.14 0.15 0.14 0.15 4.3e-04 1.7e-04 3.4e-04 2.0e-04
9 PL gene expression ENSRNOG00000030530 0.22 0.14 0.0e+00 0.24 0.23 0.23 0.23 4.1e-18 3.7e-17 2.0e-17 1.6e-17
10 PL intron excision ratio chr7:10014599:10016545 0.06 0.06 7.6e-03 0 0.01 0.02 0.01 2.0e-01 5.5e-02 1.0e-02 6.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail6.119.824.0-4.74.5-4.8-4.6-4.9-4.14.5-4.9-4.52.5
BMI without tail1.83.76.8-2.01.9-1.9-2.0-2.6-1.41.8-2.6-1.80.1
Body weight1.04.45.6-2.22.2-2.3-2.2-2.4-1.91.9-2.4-2.11.0
Epididymis fat weight0.30.61.00.8-1.00.90.80.70.8-0.70.70.9-0.7
Glucose1.52.33.0-1.71.4-1.5-1.5-1.7-1.41.6-1.7-1.60.8
Heart weight0.10.20.70.4-0.80.40.50.10.5-0.00.20.3-0.7
Left kidney weight0.00.00.10.20.10.1-0.00.3-0.10.00.40.10.2
Right kidney weight1.13.23.82.0-1.82.01.81.81.8-1.51.91.9-1.4
Tail length3.410.211.93.3-3.13.53.23.03.3-3.33.13.4-2.6
Length with tail1.76.37.92.7-2.42.62.62.82.3-2.72.82.6-1.3
Length without tail0.10.20.90.20.10.00.10.7-0.2-0.20.70.10.9
Liver weight, left1.82.93.7-1.81.8-1.8-1.8-1.9-1.61.7-1.9-1.70.8
Liver weight, right1.32.23.1-1.51.7-1.5-1.7-1.4-1.51.7-1.3-1.41.1
Parametrial fat weight0.40.91.30.9-0.91.11.00.61.1-0.90.70.9-0.9
Retroperitoneal fat weight0.20.50.9-0.70.7-0.6-0.7-1.0-0.50.9-0.9-0.70.1
Intraocular pressure0.20.31.4-0.1-0.50.40.3-0.70.5-0.3-0.70.0-1.2
Extensor digitorum longus weight3.514.020.7-4.04.1-3.8-3.9-4.5-3.13.6-4.5-3.61.1
Soleus weight8.624.928.9-5.35.2-5.2-5.2-5.4-4.75.1-5.3-5.12.8
Tibialis anterior weight0.82.84.1-1.72.0-1.8-1.8-1.8-1.51.5-1.9-1.60.8
Tibia length0.82.32.71.6-1.61.41.61.51.6-1.71.51.6-1.2
Number of licking bursts0.20.21.6-0.1-0.00.00.1-0.60.4-0.1-0.60.1-1.3
Food consumed during 24 hour testing period0.50.61.3-0.80.8-0.6-0.8-1.2-0.60.7-1.1-0.8-0.3
Times rat made contact with spout0.20.31.0-0.40.3-0.1-0.3-0.80.00.2-0.8-0.2-1.0
Mean time between licks in bursts4.15.86.52.5-2.62.32.52.42.5-2.52.32.5-1.9
Mean num. licks in bursts0.00.00.1-0.20.1-0.0-0.2-0.1-0.30.2-0.0-0.20.4
Std. dev. time between licks in bursts0.60.71.00.9-0.80.60.81.00.8-0.81.00.9-0.4
Water consumed over 24 hours0.60.81.1-0.91.0-0.9-1.0-0.8-1.00.9-0.7-0.90.6
Indifference point 0 sec0.20.40.6-0.60.6-0.8-0.7-0.5-0.70.7-0.4-0.60.7
Indifference point AUC0.60.70.90.9-1.00.90.90.90.9-0.80.80.8-0.6
Indifference point function ln k0.20.30.5-0.50.5-0.5-0.5-0.7-0.30.5-0.7-0.5-0.0
Indifference point function log k0.20.30.5-0.50.5-0.5-0.5-0.7-0.30.5-0.7-0.5-0.0
Delay discounting total patch changes 0 sec0.10.20.3-0.50.4-0.6-0.5-0.4-0.50.5-0.4-0.40.4
Delay discounting total patch changes 12 sec0.30.40.7-0.70.5-0.5-0.7-0.8-0.50.7-0.9-0.50.1
Delay discounting total patch changes 18 sec0.91.21.41.2-1.21.11.21.21.1-1.01.21.2-0.6
Delay discounting total patch changes 24 sec0.00.00.10.1-0.20.10.20.20.0-0.00.20.00.2
Delay discounting total patch changes 6 sec0.10.10.20.3-0.50.30.20.40.10.10.40.30.0
Delay discounting time to switch 0 sec1.31.94.7-1.21.6-1.2-1.5-0.5-1.81.4-0.4-1.32.2
Delay discounting water rate 0 sec0.40.63.10.1-0.30.30.4-0.70.9-0.4-0.80.5-1.8
Delay discounting water rate 12 sec1.01.53.9-1.20.9-1.1-0.9-2.0-0.40.8-2.0-1.0-0.9
Delay discounting water rate 18 sec0.91.26.70.3-0.70.60.7-0.81.3-0.7-0.90.7-2.6
Delay discounting water rate 24 sec0.70.93.7-0.50.1-0.1-0.1-1.50.5-0.0-1.6-0.1-1.9
Delay discounting water rate 6 sec0.60.94.00.6-0.80.70.9-0.21.3-0.8-0.20.7-2.0
Locomotor activity2.33.76.72.1-1.71.81.82.51.4-2.12.61.9-0.2
Locomotor testing distance1.32.13.71.6-1.51.41.41.81.1-1.41.91.4-0.2
Locomotor testing rearing0.10.10.40.2-0.20.10.3-0.10.4-0.3-0.20.2-0.7
Light reinforcement 15.510.114.53.4-3.23.13.33.82.8-3.53.73.0-1.0
Light reinforcement 21.82.44.01.6-1.71.41.62.01.2-1.91.91.4-0.1
Reaction time number correct0.50.71.9-0.60.5-0.4-0.4-1.40.10.5-1.4-0.4-1.3
Reaction time mean minus median0.60.81.10.9-0.90.91.00.71.0-0.90.61.0-1.0
Reaction time mean minus median AUC0.00.00.20.00.3-0.1-0.00.2-0.2-0.00.2-0.00.4
Reaction time num false alarms0.10.20.6-0.20.1-0.2-0.1-0.60.2-0.2-0.80.0-0.7
Reaction time num false alarms AUC0.20.20.8-0.30.1-0.2-0.1-0.70.3-0.2-0.90.0-0.9
Reaction time trials correct on left0.50.71.9-0.60.5-0.4-0.4-1.40.10.5-1.4-0.4-1.3
Reaction time trials on left0.50.71.9-0.60.5-0.4-0.5-1.40.00.5-1.4-0.4-1.2
Reaction time mean0.10.10.2-0.30.3-0.3-0.2-0.1-0.30.4-0.2-0.30.3
Reaction time mean AUC0.10.20.3-0.40.4-0.4-0.3-0.2-0.50.6-0.3-0.50.4
Median of all reaction times0.40.60.9-0.80.8-0.8-0.8-0.5-0.90.9-0.6-0.90.8
Reaction time omissions0.10.10.20.3-0.50.30.40.40.1-0.20.40.1-0.0
Reaction time false alarm rate0.00.00.0-0.10.1-0.2-0.1-0.0-0.1-0.2-0.2-0.00.2
Reaction time premature initiation rate0.91.31.91.1-1.41.11.30.91.3-1.20.81.1-1.2
Reaction time premature initiations0.91.23.80.8-1.21.01.20.21.4-1.00.11.0-1.9
Std. dev. reaction times0.10.10.20.4-0.40.30.50.30.4-0.30.30.4-0.4
Reaction time trials completed0.50.71.9-0.60.5-0.4-0.5-1.40.00.5-1.4-0.4-1.2
Reaction time trials AUC0.50.72.0-0.60.4-0.3-0.4-1.40.20.4-1.4-0.3-1.4
Social response proportion0.50.51.20.8-0.70.60.71.10.4-0.61.10.70.1
Social responses5.77.310.22.9-2.72.62.73.22.4-2.83.22.8-1.2
Social time0.81.01.3-1.00.9-1.1-1.0-0.8-1.11.1-0.7-1.11.1
Conditioned locomotion1.01.22.8-1.21.0-1.0-1.0-1.6-0.61.0-1.7-1.0-0.3
Cocaine response after cond. corrected4.65.110.0-2.52.1-1.9-2.2-3.2-1.62.2-3.2-2.3-0.1
Cocaine response after cond. not corrected4.65.110.2-2.52.1-1.9-2.2-3.2-1.62.1-3.2-2.2-0.1
Cocaine response before conditioning0.60.71.10.9-0.70.70.81.00.8-1.01.01.0-0.4
Saline control response0.00.10.1-0.20.2-0.3-0.2-0.3-0.10.2-0.3-0.20.1
Condit. Reinf. active minus inactive responses1.92.43.31.5-1.81.51.71.11.8-1.51.01.6-1.8
Condit. Reinf. active-inactive response ratio0.10.10.5-0.2-0.50.00.2-0.50.30.2-0.6-0.1-0.7
Condit. Reinf. active responses1.82.53.11.6-1.71.51.71.31.8-1.61.21.7-1.6
Condit. Reinf. inactive responses1.41.72.21.4-1.11.21.31.21.4-1.51.21.5-1.3
Condit. Reinf. lever presses2.12.93.71.7-1.91.61.91.41.9-1.71.31.7-1.6
Condit. Reinf. lever reinforcers received1.41.92.91.4-1.61.31.51.01.6-1.40.91.5-1.7
Pavlov. Cond. lever latency0.50.60.8-0.80.9-0.8-0.9-0.7-0.90.8-0.6-0.80.7
Pavlov. Cond. magazine entry latency0.60.60.90.8-0.70.80.80.80.8-0.90.70.9-0.7
Pavlov. Cond. change in total contacts0.40.50.80.7-0.90.70.80.60.8-0.70.50.7-0.7
Pavlov. Cond. index score0.70.91.10.9-1.01.01.00.81.0-1.00.71.0-1.0
Pavlov. Cond. latency score0.50.70.80.8-0.80.80.90.80.9-0.90.70.8-0.7
Pavlov. Cond. lever contacts0.60.81.20.9-1.00.91.00.61.1-0.90.50.9-1.1
Pavlov. Cond. magazine entry number0.81.01.2-1.00.9-1.0-1.0-1.0-1.01.1-0.9-1.10.8
Pavlov. Cond. intertrial magazine entries0.20.30.8-0.50.4-0.6-0.4-0.9-0.20.5-0.9-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.91.01.0-0.91.01.00.91.0-1.00.81.0-0.8
Pavlov. Cond. response bias1.62.22.71.5-1.61.51.61.21.7-1.51.11.5-1.6
Conditioned reinforcement - actives1.81.82.41.4-1.41.41.41.61.2-1.41.51.4-0.5
Conditioned reinforcement - inactives0.20.30.6-0.60.5-0.5-0.4-0.7-0.30.1-0.8-0.50.0
Conditioned locomotion6.68.09.82.9-2.92.93.03.12.7-3.13.02.8-1.6
Intermittent access intake day 1-15 change6.06.07.62.6-2.62.62.52.32.5-2.02.52.8-1.8
Intermittent access intake escalation6.16.07.82.6-2.72.72.52.02.7-1.92.12.8-2.4
Intermittent access intake escalation 27.07.08.72.8-2.92.92.72.22.9-2.02.32.9-2.5
Intermitt. access day 1 inactive lever presses0.20.20.70.4-0.50.50.40.00.6-0.60.00.4-0.8
Intermitt. access day 15 inactive lever presses0.60.60.80.8-0.80.80.90.70.9-0.80.70.9-0.7
Intermitt. access escalation Index0.40.30.9-0.50.6-0.6-0.6-0.1-0.70.3-0.1-0.60.9
Intermittent access day 1 total infusions0.10.10.2-0.20.2-0.2-0.00.1-0.3-0.3-0.1-0.40.5
Intermittent access day 15 total infusions2.12.32.81.6-1.61.61.71.41.6-1.61.31.6-1.2
Intermittent access terminal intake (last 3 days)1.01.11.31.1-1.11.11.21.11.0-1.11.11.2-0.6
Intermittent access total infusions0.30.30.50.5-0.50.50.70.50.6-0.70.40.5-0.3
Intermittent access day 1 locomotion0.60.60.90.8-0.80.80.90.80.8-1.00.70.7-0.6
Intermittent access day 15 total locomotion3.94.15.12.1-2.12.12.22.12.0-2.32.02.1-1.3
Intermittent access total locomotion1.01.11.61.1-1.01.01.21.30.9-1.21.11.0-0.4
Intermittent access standard deviation2.72.93.41.7-1.81.81.81.51.8-1.61.41.8-1.7
Cocaine induced anxiety0.40.41.20.6-0.40.40.41.00.1-0.41.10.40.8
Post-drug Anxiety0.40.51.20.6-0.50.50.51.10.2-0.61.10.50.7
Baseline Anxiety0.40.51.30.6-0.60.60.70.20.8-0.70.20.6-1.1
Lifetime Intake0.10.10.20.3-0.30.30.40.40.3-0.40.30.3-0.1
Incentive Sensitization - Responses0.10.10.30.2-0.40.40.2-0.10.40.1-0.00.3-0.5
Incentive Sensitization - Breakpoint0.10.10.30.3-0.50.50.30.00.40.00.10.4-0.5
Progressive ratio test 1 active lever presses0.10.10.2-0.00.0-0.00.2-0.20.2-0.5-0.30.0-0.4
Progressive ratio test 1 breakpoint0.10.10.2-0.10.1-0.10.1-0.20.2-0.4-0.4-0.0-0.4
Progressive ratio test 1 inactive lever presses0.10.10.30.3-0.20.20.30.30.2-0.60.30.2-0.1
Progressive ratio test 2 active lever presses0.20.20.40.4-0.50.50.50.20.6-0.40.10.5-0.6
Progressive ratio test 2 breakpoint0.20.20.30.4-0.50.50.50.40.5-0.40.30.5-0.4
Progressive ratio test 2 inactive lever presses0.00.00.10.2-0.10.10.10.3-0.0-0.20.30.10.4
Total sessions with >9 infusions0.10.10.3-0.20.3-0.3-0.20.0-0.30.1-0.0-0.20.5
Short access day 1 total inactive lever presses0.10.10.30.3-0.30.30.30.40.2-0.60.40.30.0
Short access day 10 total inactive lever presses0.00.00.0-0.00.0-0.0-0.0-0.20.0-0.1-0.1-0.0-0.1
Short access day 1 total infusions0.20.20.60.4-0.20.20.30.80.1-0.40.80.30.6
Short access day 10 total infusions0.20.20.70.4-0.40.40.60.30.6-0.80.10.4-0.6
Short access total infusions0.00.00.10.00.1-0.10.00.1-0.1-0.00.1-0.00.2
Short access day 1 locomotion0.80.91.61.0-0.90.90.91.20.7-0.91.20.9-0.1
Short access day 10 total locomotion3.84.24.72.1-2.12.12.21.92.1-2.01.82.2-1.7
Short access total locomotion0.80.81.20.9-0.80.81.01.10.8-1.01.00.9-0.4
Compulsive drug intake1.61.62.0-1.31.4-1.4-1.4-1.0-1.41.1-1.0-1.41.3
One hour access (0.3 mA shock)0.10.10.1-0.30.3-0.3-0.1-0.2-0.2-0.1-0.4-0.30.3
One hour access (shock baseline)0.30.40.60.5-0.60.60.70.30.8-0.80.10.6-0.8
Number of responses in last shaping day0.10.20.40.4-0.40.40.40.40.3-0.70.40.3-0.0
Context. condit. distance diff. score0.00.10.2-0.10.40.1-0.2-0.3-0.00.0-0.3-0.0-0.3
Locomotion velocity, session 10.30.41.10.5-0.50.30.40.90.0-0.31.00.30.8
Locomotion distance, session 10.60.72.90.50.20.20.11.3-0.4-0.31.40.31.7
Locomotion velocity, session 23.94.69.42.3-1.72.01.93.01.5-2.13.12.10.3
Locomotion distance, session 21.11.64.61.1-0.90.80.92.10.2-0.82.20.81.5
Locomotion velocity, session 37.58.79.93.1-2.93.13.02.93.0-3.12.83.1-2.3
Locomotion distance, session 30.10.10.30.2-0.10.20.20.10.4-0.3-0.00.3-0.5
Stereotopy head waving bouts, day 35.66.89.02.8-2.42.62.63.02.4-2.73.02.7-1.3
Stereotopy head waving duration, day 36.57.99.33.0-2.72.92.93.12.7-2.93.02.9-1.7
Locomotion velocity, session 71.21.31.81.2-0.61.31.01.01.3-1.40.91.4-1.2
Locomotion distance, session 70.10.20.9-0.20.30.1-0.2-0.60.2-0.0-0.70.0-0.9
Stereotopy head waving bouts, day 70.10.20.70.20.0-0.00.10.6-0.2-0.10.60.10.8
Stereotopy head waving duration, day 70.20.30.90.5-0.30.20.30.9-0.0-0.30.90.30.8
Locomotion velocity, session 80.91.02.61.0-0.41.00.71.60.4-1.01.61.00.6
Locomotion distance, session 80.30.41.10.7-0.30.70.51.00.3-0.61.00.60.4
Degree of sensitization distance0.30.30.6-0.50.8-0.4-0.7-0.6-0.50.5-0.5-0.50.2
Degree of sensitization stereotypy2.12.32.9-1.51.5-1.7-1.5-1.2-1.71.6-1.2-1.61.7
Condit. Reinf. active minus inactive responses5.05.66.42.5-2.42.32.52.52.3-2.52.52.5-1.5
Condit. Reinf. active-inactive response ratio2.22.43.41.6-1.81.51.71.31.7-1.51.21.5-1.5
Condit. Reinf. active responses3.74.67.42.3-2.02.12.12.71.8-2.22.72.2-0.4
Condit. Reinf. inactive responses0.91.02.71.0-0.60.80.71.70.3-0.81.70.81.0
Incentive salience index mean2.63.25.21.9-1.61.71.82.31.5-1.82.21.8-0.4
Condit. Reinf. lever presses0.50.63.80.00.4-0.3-0.30.9-0.70.20.9-0.22.0
Time in familiar zone, hab. session 12.52.43.31.5-1.61.81.61.21.6-1.51.21.5-1.6
Time in novel zone, hab. session 11.51.52.3-1.21.2-1.4-1.2-0.8-1.41.2-0.8-1.21.5
Total zone transitions, hab. session 10.81.23.11.1-0.80.70.91.70.5-1.01.81.00.7
Total locomotion distance, hab. session 11.21.74.61.3-0.60.90.92.10.5-1.22.11.21.0
Locomotion velocity, hab. session 11.62.45.81.7-0.91.21.22.40.8-1.52.41.50.6
Time in familiar zone, hab. session 26.66.88.52.6-2.92.92.82.22.8-2.62.22.6-2.5
Time in novel zone, hab. session 25.25.26.2-2.32.5-2.5-2.4-2.1-2.42.3-2.0-2.32.0
Total zone transitions, hab. session 20.71.04.8-0.40.8-0.9-0.70.4-1.20.60.6-0.62.2
Total locomotion distance, hab. session 20.91.23.51.1-0.80.80.91.60.4-0.91.90.90.7
Locomotion velocity, hab. session 20.91.24.01.1-0.70.70.81.70.2-0.82.00.81.1
Novel to familiar place preference ratio5.15.46.6-2.32.4-2.4-2.4-1.8-2.62.4-1.7-2.42.6
Novelty place preference3.23.34.6-1.81.9-1.9-1.9-1.4-2.11.9-1.3-1.92.2
Time in novel zone, NPP test3.33.54.4-1.92.0-1.9-2.0-1.5-2.11.9-1.4-1.92.0
Total zone transitions, NPP test0.30.52.8-0.10.3-0.4-0.30.6-0.70.30.7-0.31.7
Total locomotion distance, NPP test0.30.42.3-0.00.4-0.4-0.30.6-0.60.20.7-0.21.5
Locomotion velocity, NPP test0.30.42.10.20.1-0.2-0.00.9-0.4-0.00.90.01.4
Pavlov. Cond. lever latency0.20.20.6-0.3-0.4-0.20.1-0.70.10.3-0.8-0.3-0.8
Pavlov. Cond. magazine entry latency4.35.66.52.5-2.12.62.32.42.3-2.52.42.5-1.6
Pavlov. Cond. change in total contacts0.40.40.60.7-0.20.70.40.80.6-0.80.80.8-0.3
Pavlov. Cond. index score1.01.32.31.3-0.61.20.91.50.9-1.31.51.3-0.2
Pavlov. Cond. latency score1.01.22.61.2-0.51.10.81.60.7-1.21.61.20.1
Pavlov. Cond. lever contacts0.30.41.10.50.20.40.11.0-0.0-0.51.00.50.8
Pavlov. Cond. magazine entry number1.41.72.1-1.41.1-1.4-1.2-1.5-1.31.4-1.4-1.40.8
Pavlov. Cond. intertrial magazine entries0.20.21.00.3-0.50.30.4-0.10.6-0.3-0.10.3-1.0
Pavlov. Cond. lever-magazine prob. diff.1.51.82.91.5-0.91.51.21.71.1-1.51.71.5-0.4
Pavlov. Cond. response bias2.02.43.11.7-1.21.71.51.71.5-1.71.71.7-0.9
Bone: apparent density0.71.25.7-0.60.8-0.7-0.90.3-1.41.00.4-1.02.4
Bone surface0.71.37.4-0.10.4-0.4-0.51.1-1.20.51.3-0.52.7
Bone volume0.81.37.6-0.20.5-0.5-0.61.0-1.30.71.1-0.62.8
Bone: connectivity density0.81.34.3-0.91.0-0.9-1.1-0.1-1.51.1-0.0-1.12.1
Bone: cortical apparent density1.21.62.2-1.41.1-1.2-1.2-1.4-1.21.5-1.3-1.40.6
Bone: cortical area0.71.11.6-1.01.3-1.2-1.1-0.6-1.20.9-0.6-1.01.2
Bone: cortical porosity0.30.40.90.6-0.50.50.50.90.3-0.50.90.50.4
Bone: cortical porosity0.20.21.20.00.2-0.1-0.10.6-0.40.10.5-0.11.1
Bone: cortical thickness1.32.22.6-1.51.6-1.6-1.6-1.2-1.61.5-1.3-1.51.4
Bone: cortical thickness0.10.20.8-0.1-0.20.00.1-0.50.4-0.0-0.50.1-0.9
Bone: cortical tissue density0.91.11.6-1.20.8-1.0-1.0-1.2-1.01.3-1.2-1.20.5
Bone: elastic displacement0.00.00.20.1-0.40.20.30.20.1-0.10.20.00.2
Bone: elastic work0.40.60.8-0.80.7-0.6-0.7-0.8-0.80.9-0.7-0.90.7
Bone: endosteal estimation0.10.20.4-0.40.6-0.6-0.5-0.5-0.40.3-0.4-0.40.2
Bone: endosteal perimeter0.30.51.00.8-0.50.60.61.00.5-0.81.00.70.1
Bone: final force1.32.13.0-1.41.7-1.6-1.6-1.3-1.51.4-1.3-1.41.1
Bone: final moment1.01.72.4-1.31.5-1.4-1.4-1.2-1.31.3-1.2-1.31.0
Bone: marrow area0.10.20.4-0.40.6-0.6-0.5-0.4-0.40.3-0.4-0.40.2
Bone: maximum diameter0.61.02.21.1-0.80.80.91.50.6-1.11.51.00.2
Bone: maximum force1.12.02.8-1.41.7-1.6-1.5-1.4-1.31.4-1.4-1.30.9
Bone: maximum moment1.01.72.2-1.31.5-1.4-1.4-1.3-1.21.3-1.3-1.30.8
Bone: minimum diameter0.00.00.10.20.3-0.10.00.30.0-0.30.20.20.1
Bone: periosteal estimation0.30.61.0-0.71.0-1.0-0.9-0.4-0.90.6-0.4-0.70.9
Bone: periosteal perimeter0.10.10.40.20.10.00.10.6-0.1-0.30.60.20.6
Bone: post-yield work0.20.30.7-0.50.9-0.6-0.6-0.7-0.20.2-0.8-0.3-0.2
Bone: stiffness2.43.75.4-1.92.3-2.3-2.1-1.8-1.91.8-1.9-1.81.2
Bone: tissue strength2.12.02.4-1.51.5-1.6-1.5-1.3-1.51.5-1.3-1.51.2
Bone: trabecular number0.40.72.10.8-0.60.70.51.40.1-0.51.40.60.8
Bone: trabecular spacing0.60.83.2-0.40.2-0.2-0.1-1.40.50.1-1.5-0.1-1.8
Bone: trabecular thickness1.51.88.6-0.71.0-0.9-1.00.5-1.71.10.6-1.12.9
Bone: trabecular tissue density1.11.62.5-1.31.4-1.3-1.3-1.5-1.01.2-1.6-1.10.1
Breakpoint value in progressive ratio session5.66.27.22.6-2.72.62.72.42.6-2.52.32.6-2.0
Distance traveled before self-admin0.91.02.0-0.90.9-0.9-1.1-0.9-1.11.4-0.7-1.00.8
Distance traveled after self-admin0.30.40.70.7-0.60.70.60.70.5-0.30.90.6-0.2
Delta time in closed arm before/after self-admin0.90.82.4-0.70.4-0.5-0.5-1.50.00.7-1.5-0.4-1.2
Delta time in open arm before/after self-admin1.51.41.8-1.21.2-1.1-1.3-1.0-1.31.3-1.0-1.31.0
Diff in mean of infusions in LGA sessions2.02.22.61.6-1.61.61.61.61.4-1.51.51.4-1.0
Extinction: sum of active levers before priming1.51.51.91.2-1.21.31.31.01.4-1.40.91.2-1.2
Active lever presses in extinction session 61.81.82.61.5-1.51.41.41.51.2-1.21.61.2-0.4
Delta distance traveled before/after self-admin2.02.12.61.6-1.41.51.51.61.4-1.61.51.5-0.8
Delta ambulatory time before/after self-admin2.12.32.91.6-1.41.51.51.71.4-1.71.71.6-0.7
Time in closed arm before self-admin1.11.22.9-0.91.1-0.9-1.2-0.4-1.41.4-0.3-1.01.7
Time in closed arm after self-admin0.00.00.10.1-0.20.20.0-0.10.20.40.00.2-0.3
Time in open arm before self-admin0.91.02.21.0-0.90.81.10.91.1-1.50.81.0-0.8
Time in open arm after self-admin0.80.81.1-1.00.9-1.0-0.9-1.0-0.90.7-1.1-1.00.5
Sum of active levers in priming session hrs 5-60.00.00.1-0.10.1-0.1-0.00.1-0.2-0.00.0-0.20.3
Time to tail flick, vehicle, before self-admin0.50.51.20.6-0.40.40.61.10.2-0.91.00.30.6
Time to tail flick, vehicle, after self-admin0.30.41.10.5-0.60.60.50.10.8-0.20.10.7-1.1
Time to tail flick, test, before self-admin0.20.20.80.3-0.20.10.20.7-0.1-0.50.70.10.9
Time to tail flick, test, after self-admin0.20.30.60.6-0.50.50.40.60.4-0.10.70.7-0.1
Delta time to tail flick, vehicle, before/after SA0.40.41.2-0.40.2-0.2-0.4-1.10.10.9-0.90.0-1.0
Delta time to tail flick, test, before/after SA0.50.41.50.6-0.60.70.40.10.80.00.20.8-1.2
Ambulatory time before self-admin0.80.91.8-0.90.8-0.8-1.0-0.8-1.01.3-0.7-1.00.8
Ambulatory time after self-admin0.20.20.40.5-0.40.50.40.50.3-0.10.60.4-0.1
Total heroin consumption1.82.22.71.5-1.51.51.61.61.3-1.61.61.4-0.7
Area under the delay curve2.12.22.7-1.61.6-1.5-1.5-1.6-1.51.3-1.6-1.60.9
Delay disc. indifference point, 0s delay8.79.412.6-3.03.2-3.2-3.2-2.2-3.53.2-2.1-3.23.6
Delay disc. indifference point, 16s delay0.10.10.2-0.40.3-0.3-0.2-0.4-0.30.0-0.4-0.40.1
Delay disc. indifference point, 2s delay5.56.17.4-2.62.7-2.6-2.6-2.2-2.62.3-2.3-2.62.1
Delay disc. indifference point, 24s delay0.80.81.3-1.00.8-1.0-0.8-1.1-0.80.6-1.1-1.00.3
Delay disc. indifference point, 4s delay0.80.81.1-1.01.0-1.0-0.9-0.8-1.00.6-0.8-1.00.9
Delay disc. indifference point, 8s delay1.11.12.0-1.11.1-0.9-1.1-1.4-0.81.0-1.4-1.00.0
Delay discount exponential model param1.92.02.41.5-1.61.51.41.51.4-1.21.61.5-0.8
Delay discount hyperbolic model param2.72.93.51.8-1.91.71.81.81.7-1.51.81.8-1.1
Fecal boli incidents, locomotor time 11.41.52.2-1.31.4-1.1-1.3-1.5-1.11.0-1.4-1.20.5
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.20.20.30.40.2-0.30.40.4-0.2
Time >=10cm from walls, locomotor time 11.51.52.6-1.11.2-1.1-1.3-0.9-1.51.6-0.6-1.21.5
Bouts of movement, locomotor time 10.50.60.90.7-0.40.70.70.50.8-1.00.50.9-1.0
Total resting periods, locomotor time 10.50.61.00.8-0.50.80.70.60.8-1.00.60.9-0.8
Rest time, locomotor task time 10.70.81.31.0-0.50.90.70.90.8-0.91.01.2-0.7
Distance moved, locomotor task time 11.51.73.1-1.21.1-1.2-1.3-0.9-1.51.5-0.7-1.51.8
Vertical activity count, locomotor time 10.60.61.2-0.80.3-0.6-0.6-1.1-0.50.9-1.1-1.00.0
Time >=10cm from walls, locomotor time 21.71.82.7-1.41.4-1.2-1.4-1.7-1.11.4-1.6-1.20.4
Bouts of movement, locomotor time 20.40.51.20.7-0.50.50.61.10.2-0.61.10.50.5
Total resting periods, locomotor time 20.40.41.20.6-0.50.40.51.10.2-0.51.10.40.6
Rest time, locomotor task time 20.50.51.10.8-0.60.70.71.00.5-0.61.10.8-0.1
Distance moved, locomotor task time 20.60.71.1-0.90.8-0.8-0.8-1.0-0.70.8-1.0-0.80.4
Vertical activity count, locomotor time 20.60.61.5-0.80.7-0.5-0.8-1.2-0.40.7-1.2-0.8-0.3
Weight adjusted by age0.40.51.3-0.60.4-0.4-0.5-1.1-0.10.6-1.1-0.5-0.7
Seeking ratio, delayed vs. immediate footshock4.04.65.92.2-2.12.12.32.42.0-2.42.42.1-1.2
Locomotion in novel chamber0.20.21.00.3-0.50.40.40.00.5-0.10.10.5-1.0
Locomotion in novel chamber post-restriction1.41.62.21.2-1.11.31.21.01.4-1.30.91.5-1.5
Progressive ratio0.00.10.1-0.20.3-0.1-0.3-0.3-0.10.4-0.3-0.1-0.1
Food seeking constrained by brief footshock0.50.61.20.9-0.40.80.61.00.6-0.91.11.0-0.2
Seeking ratio, punishment vs. effort0.30.30.70.5-0.40.50.50.80.3-0.80.80.50.0
Run reversals in cocaine runway, females0.40.40.70.8-0.60.70.60.70.6-0.50.80.8-0.3
Run reversals in cocaine runway, males1.31.31.91.2-1.21.21.11.31.0-1.01.41.2-0.5
Latency to leave start box in cocaine runway0.30.31.40.3-0.50.10.30.8-0.20.20.90.11.2
Latency to leave start box in cocaine runway, F1.21.35.6-0.80.7-1.1-0.9-0.1-1.41.20.0-1.12.4
Latency to leave start box in cocaine runway, M3.13.04.01.8-1.91.91.81.32.0-1.51.31.8-1.9
Cd content in liver0.40.40.8-0.70.7-0.9-0.6-0.5-0.70.6-0.6-0.70.7
Co content in liver0.60.81.10.9-0.80.80.90.90.9-1.00.81.0-0.7
Cu content in liver0.20.31.2-0.30.7-0.5-0.50.1-0.60.30.1-0.41.1
Fe content in liver0.30.30.60.6-0.30.70.50.50.7-0.70.30.8-0.7
K content in liver0.20.20.60.20.4-0.2-0.10.7-0.2-0.20.60.30.8
Mg content in liver0.20.21.00.00.5-0.4-0.30.5-0.40.00.50.01.0
Mn content in liver1.11.33.51.1-0.40.90.71.90.4-1.01.91.00.9
Na content in liver0.80.92.2-0.71.4-1.0-1.0-0.1-1.00.6-0.2-0.71.5
Rb content in liver0.60.72.0-0.71.0-0.9-0.9-0.2-1.10.8-0.2-0.81.4
Se content in liver0.60.71.10.9-0.40.90.71.00.8-1.01.01.0-0.4
Sr content in liver0.20.20.90.2-0.30.30.3-0.20.5-0.3-0.30.2-1.0
Zn content in liver2.12.34.81.4-1.71.51.60.81.8-1.50.71.5-2.2