Hub : Genes

Atp2b2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000030269 0.88 0.04 0.0e+00 0.5 0.52 0.54 0.54 1.0e-63 9.8e-68 1.3e-71 5.6e-72
2 Adipose mRNA stability ENSRNOG00000030269 0.33 0.1 0.0e+00 0.25 0.26 0.25 0.25 4.8e-27 8.5e-29 9.3e-28 6.8e-28
3 BLA gene expression ENSRNOG00000030269 0.14 0.07 5.4e-06 0.05 0.09 0.07 0.08 1.0e-03 1.5e-05 2.1e-04 4.7e-05
4 BLA intron excision ratio chr4:146902170:146905660 0.06 0.04 7.4e-03 0.01 0.02 0.02 0.01 5.5e-02 3.2e-02 4.6e-02 7.1e-02
5 Brain gene expression ENSRNOG00000030269 0.42 0.09 0.0e+00 0.3 0.36 0.35 0.35 1.3e-28 2.3e-34 8.7e-34 5.2e-34
6 Brain isoform ratio ENSRNOT00000111682 0.07 0.05 3.4e-03 0 0.02 0.03 0 2.3e-01 2.9e-03 1.2e-03 1.7e-01
7 Brain intron excision ratio chr4:146902170:146905660 0.05 0.03 6.7e-04 0.02 0.02 0.01 0.01 2.7e-03 9.6e-03 3.8e-02 1.6e-02
8 Brain intron excision ratio chr4:146948899:146954022 0.05 0.03 9.9e-03 0 0.01 -0 -0 2.3e-01 1.3e-02 5.4e-01 4.1e-01
9 Brain mRNA stability ENSRNOG00000030269 0.16 0.06 4.4e-14 0.12 0.15 0.14 0.14 1.7e-11 4.6e-14 2.2e-13 6.4e-13
10 IL gene expression ENSRNOG00000030269 0.19 0.1 3.9e-03 0.05 0.07 0.03 0.07 2.2e-02 9.4e-03 7.8e-02 1.1e-02
11 Liver gene expression ENSRNOG00000030269 0.06 0.03 1.1e-07 0.05 0.06 0.06 0.05 4.2e-06 2.9e-07 2.0e-07 1.4e-06
12 NAcc gene expression ENSRNOG00000030269 0.07 0.04 9.9e-04 0.03 0.03 0.03 0.01 5.3e-03 5.6e-03 3.6e-03 3.5e-02
13 OFC gene expression ENSRNOG00000030269 0.38 0.12 1.2e-05 0.17 0.2 0.18 0.14 6.1e-05 1.5e-05 5.4e-05 3.2e-04
14 PL gene expression ENSRNOG00000030269 0.21 0.07 3.3e-14 0.14 0.17 0.15 0.14 6.8e-11 5.5e-13 1.1e-11 4.1e-11
15 PL mRNA stability ENSRNOG00000030269 0.08 0.05 1.4e-03 0.02 0.04 0.02 0.03 1.4e-02 5.7e-04 9.1e-03 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.20.73.2-0.5-1.00.81.00.2-0.70.60.30.81.1-0.51.80.80.40.3
BMI without tail0.10.31.10.60.50.20.5-0.10.4-0.4-1.00.5-0.10.20.9-0.8-0.1-0.7
Body weight0.52.15.00.30.12.00.51.6-0.6-0.5-1.22.22.1-1.62.01.41.71.2
Epididymis fat weight0.51.22.31.21.21.1-1.00.5-1.5-1.3-0.50.71.1-1.30.61.11.21.2
Glucose0.30.51.90.0-0.11.40.7-0.0-0.70.0-0.41.11.3-0.20.90.20.6-0.6
Heart weight0.10.10.4-0.5-0.10.30.1-0.0-0.60.50.20.00.40.00.50.30.20.1
Left kidney weight0.82.45.51.00.8-1.9-0.7-1.11.8-0.7-1.0-1.3-2.21.5-2.3-2.3-1.7-1.1
Right kidney weight0.71.94.92.22.0-0.9-2.1-0.11.0-2.0-1.5-0.5-1.20.0-2.1-1.1-0.30.5
Tail length0.30.83.21.31.40.2-0.30.10.8-1.2-1.80.5-0.40.40.1-1.20.1-0.6
Length with tail0.51.76.21.31.41.4-0.41.70.3-1.4-2.51.91.1-1.00.30.11.30.8
Length without tail0.51.02.70.40.40.8-0.91.5-0.4-0.6-1.01.21.1-1.2-0.51.11.01.6
Liver weight, left0.30.52.11.00.80.2-0.40.20.4-1.2-1.50.80.1-0.1-0.9-0.60.1-0.2
Liver weight, right0.30.51.81.31.0-0.3-0.80.30.1-1.3-1.20.2-0.4-0.4-0.3-0.40.00.4
Parametrial fat weight0.30.52.5-0.3-0.10.7-0.4-0.2-1.60.40.10.51.2-0.60.21.10.50.8
Retroperitoneal fat weight0.20.82.41.00.40.2-1.2-0.1-0.6-0.81.2-0.50.5-1.10.21.50.71.5
Intraocular pressure0.20.21.5-0.20.10.2-0.1-0.9-1.20.5-0.1-0.40.20.60.2-0.2-0.3-0.4
Extensor digitorum longus weight2.28.930.3-1.3-1.43.82.43.1-1.91.3-0.53.64.2-2.55.53.73.12.2
Soleus weight0.30.82.2-1.5-1.40.61.40.50.41.50.50.80.9-0.40.90.60.3-0.2
Tibialis anterior weight1.86.111.11.91.82.9-2.32.1-1.7-1.9-0.41.83.0-3.22.43.33.03.3
Tibia length0.10.41.30.20.2-0.6-0.7-0.9-0.80.30.4-0.9-0.50.4-1.2-0.1-0.50.2
Number of licking bursts1.11.34.52.11.90.7-0.80.50.7-2.1-1.60.80.0-0.40.7-0.60.6-0.2
Food consumed during 24 hour testing period0.40.42.20.70.90.2-1.3-0.1-1.5-0.6-0.3-0.10.3-0.3-0.40.30.20.7
Times rat made contact with spout0.10.10.50.20.2-0.2-0.0-0.7-0.6-0.20.0-0.5-0.30.40.3-0.3-0.3-0.3
Mean time between licks in bursts0.91.23.90.40.51.4-0.20.5-0.8-0.2-0.30.71.5-1.02.01.71.51.4
Mean num. licks in bursts1.62.05.3-2.3-2.0-1.30.9-1.4-0.92.21.8-1.4-0.71.1-1.0-0.0-1.3-0.4
Std. dev. time between licks in bursts1.11.43.4-1.5-1.3-1.01.4-1.40.31.90.5-1.0-0.91.7-0.1-0.8-1.2-1.1
Water consumed over 24 hours0.20.31.20.40.30.4-0.20.4-0.3-0.4-0.20.30.5-0.51.10.70.60.8
Indifference point 0 sec0.20.31.2-1.0-0.70.30.60.1-0.11.1-0.10.50.50.2-0.6-0.0-0.0-0.3
Indifference point AUC1.51.84.40.60.7-1.6-1.4-1.9-0.0-0.40.8-2.1-1.71.2-2.1-1.3-1.4-0.8
Indifference point function ln k1.62.26.1-0.9-1.01.61.82.1-0.10.7-1.32.51.8-1.21.91.11.40.7
Indifference point function log k1.62.26.1-0.9-1.01.61.82.1-0.10.7-1.32.51.8-1.21.91.11.40.7
Delay discounting total patch changes 0 sec0.20.41.5-1.2-0.90.30.80.2-0.11.2-0.20.70.50.2-0.6-0.1-0.1-0.3
Delay discounting total patch changes 12 sec2.33.17.1-1.1-0.8-1.70.4-2.50.71.31.0-1.8-1.72.3-2.7-2.0-2.1-2.2
Delay discounting total patch changes 18 sec0.81.14.30.10.4-1.0-1.0-1.30.20.10.2-1.1-1.10.9-2.1-1.4-1.2-1.0
Delay discounting total patch changes 24 sec0.70.82.5-0.8-0.3-0.7-0.7-1.3-0.90.91.6-1.4-0.50.6-1.3-0.1-0.8-0.3
Delay discounting total patch changes 6 sec0.20.41.5-1.1-0.80.30.7-0.6-0.51.20.60.00.40.5-0.2-0.0-0.2-0.6
Delay discounting time to switch 0 sec1.52.35.71.10.81.8-0.31.9-0.5-1.2-0.81.61.8-1.72.41.71.91.6
Delay discounting water rate 0 sec3.15.07.2-2.1-2.4-2.51.9-2.02.12.11.6-1.7-2.32.3-2.6-2.2-2.7-2.6
Delay discounting water rate 12 sec0.10.10.4-0.3-0.5-0.00.6-0.1-0.00.3-0.30.30.00.1-0.0-0.3-0.2-0.3
Delay discounting water rate 18 sec0.50.72.2-1.2-1.5-0.61.2-0.50.71.11.3-0.4-0.40.4-0.6-0.1-0.6-0.5
Delay discounting water rate 24 sec1.31.72.9-1.6-1.7-1.31.3-0.71.11.5-0.1-0.2-1.01.4-1.7-1.6-1.7-1.5
Delay discounting water rate 6 sec0.71.03.6-0.7-0.9-0.91.0-0.41.90.4-0.30.1-0.80.8-1.2-1.4-1.1-1.2
Locomotor activity0.71.23.20.90.9-0.6-0.3-1.21.4-0.8-0.7-0.5-1.10.9-1.5-1.8-0.9-1.5
Locomotor testing distance2.33.98.6-0.8-0.6-2.10.7-2.41.70.80.4-1.6-2.32.2-2.9-2.9-2.4-2.8
Locomotor testing rearing1.01.65.70.91.3-1.0-1.9-1.8-0.0-0.70.7-1.7-1.20.6-2.4-1.0-0.9-0.7
Light reinforcement 10.00.10.3-0.10.1-0.3-0.3-0.3-0.0-0.1-0.0-0.3-0.20.1-0.50.0-0.10.3
Light reinforcement 22.53.46.81.91.51.7-1.62.1-1.1-2.1-0.71.51.8-2.50.62.22.22.6
Reaction time number correct0.71.02.0-0.1-0.21.20.21.3-0.6-0.1-0.21.31.4-1.31.11.41.31.1
Reaction time mean minus median0.81.02.8-0.8-0.8-1.3-0.2-1.00.60.91.7-1.6-1.10.8-1.2-0.4-1.1-0.5
Reaction time mean minus median AUC1.41.83.9-1.4-1.4-1.50.5-1.30.81.52.0-1.8-1.31.2-1.5-0.6-1.4-1.0
Reaction time num false alarms0.60.93.6-1.2-1.1-0.21.90.11.01.2-0.60.5-0.20.90.9-0.8-0.5-1.0
Reaction time num false alarms AUC0.71.03.6-1.2-1.0-0.41.9-0.11.21.1-0.70.4-0.51.10.4-1.2-0.7-1.4
Reaction time trials correct on left0.71.02.0-0.1-0.21.20.21.3-0.6-0.1-0.21.31.4-1.31.11.41.31.1
Reaction time trials on left0.60.91.7-0.1-0.21.10.21.2-0.5-0.1-0.21.21.3-1.21.01.31.21.1
Reaction time mean1.41.96.3-0.7-0.6-1.7-0.9-1.9-0.50.82.4-2.5-1.41.0-1.6-0.2-1.4-0.3
Reaction time mean AUC1.41.96.4-0.9-0.8-1.7-0.6-1.9-0.41.02.5-2.4-1.31.0-1.4-0.1-1.3-0.3
Median of all reaction times1.21.75.7-0.5-0.5-1.5-1.0-1.9-0.90.52.4-2.3-1.20.8-1.40.0-1.2-0.1
Reaction time omissions1.72.34.5-0.6-0.8-2.10.5-1.41.70.70.4-1.5-2.11.8-1.7-2.0-2.0-1.7
Reaction time false alarm rate1.31.94.3-1.1-1.0-1.31.6-0.91.71.1-0.5-0.4-1.41.8-0.7-2.1-1.6-2.0
Reaction time premature initiation rate1.11.54.3-0.8-0.4-1.6-0.5-1.9-0.91.01.2-2.1-1.41.3-1.0-0.6-1.4-0.3
Reaction time premature initiations0.40.51.6-0.4-0.1-0.9-0.6-1.1-1.00.50.8-1.3-0.80.5-0.6-0.1-0.70.2
Std. dev. reaction times3.04.18.0-1.7-1.7-2.70.4-2.21.21.92.4-2.8-2.42.0-2.1-1.4-2.5-1.5
Reaction time trials completed0.60.91.7-0.1-0.21.10.21.2-0.5-0.1-0.21.21.3-1.21.01.31.21.1
Reaction time trials AUC0.60.81.6-0.2-0.41.10.31.2-0.60.0-0.11.11.3-1.21.01.31.11.0
Social response proportion1.61.75.72.22.2-0.1-2.40.1-0.9-2.2-1.3-0.1-0.2-0.5-1.1-0.30.20.8
Social responses1.52.04.5-0.00.0-1.9-0.1-1.60.70.10.1-1.8-2.11.9-1.6-2.0-1.8-1.6
Social time0.20.30.90.50.2-0.5-0.9-0.6-0.8-0.60.2-0.9-0.2-0.00.20.5-0.20.9
Conditioned locomotion1.41.73.21.71.71.8-0.71.10.5-1.7-1.61.71.3-1.10.90.01.4-0.0
Cocaine response after cond. corrected2.42.79.20.30.5-1.8-0.1-1.31.70.1-1.3-1.0-2.22.1-1.9-3.0-2.0-2.1
Cocaine response after cond. not corrected3.33.79.80.30.5-2.5-0.7-1.71.4-0.0-0.8-1.6-2.72.2-2.9-3.1-2.4-1.9
Cocaine response before conditioning0.40.52.3-0.4-0.3-1.0-0.9-0.6-0.80.11.0-1.1-0.60.0-1.50.2-0.60.5
Saline control response1.11.58.11.21.9-0.0-2.8-0.6-1.6-0.90.1-0.8-0.0-0.5-1.90.20.10.8
Condit. Reinf. active minus inactive responses1.21.53.1-1.0-0.9-1.60.1-1.6-0.31.31.4-1.8-1.31.3-1.5-0.6-1.4-0.6
Condit. Reinf. active-inactive response ratio1.61.62.6-1.4-1.6-1.41.0-1.5-0.21.61.3-1.5-1.11.6-0.8-0.7-1.5-0.9
Condit. Reinf. active responses0.81.22.8-0.7-0.5-1.3-0.3-1.60.01.01.1-1.6-1.21.1-1.7-0.7-1.3-0.7
Condit. Reinf. inactive responses0.50.62.51.01.50.5-1.60.10.2-1.0-0.50.20.2-0.7-1.0-0.00.50.2
Condit. Reinf. lever presses0.20.31.20.20.2-0.5-0.2-0.50.20.1-0.8-0.1-0.50.5-1.1-1.0-0.7-0.6
Condit. Reinf. lever reinforcers received1.01.54.1-0.7-0.4-1.5-0.4-1.7-0.21.11.0-1.7-1.31.3-2.0-0.9-1.4-0.8
Pavlov. Cond. lever latency0.30.42.3-0.2-0.30.00.1-0.0-0.0-0.11.5-0.6-0.0-0.21.01.10.40.6
Pavlov. Cond. magazine entry latency0.30.30.9-0.1-0.0-0.7-0.1-0.6-0.00.4-0.7-0.4-0.50.8-0.9-0.9-0.8-0.5
Pavlov. Cond. change in total contacts1.41.95.8-0.6-0.2-1.40.4-1.01.11.0-1.1-0.5-1.51.7-2.1-2.4-1.8-1.8
Pavlov. Cond. index score0.71.02.9-0.4-0.3-1.00.2-0.70.50.7-0.9-0.2-0.81.1-1.7-1.7-1.3-1.3
Pavlov. Cond. latency score0.70.92.7-0.4-0.3-0.90.4-0.50.50.7-1.2-0.0-0.71.0-1.5-1.7-1.2-1.1
Pavlov. Cond. lever contacts0.71.03.5-0.3-0.3-0.60.6-0.51.10.6-1.40.3-0.61.0-1.2-1.9-1.1-1.6
Pavlov. Cond. magazine entry number1.11.43.50.90.91.5-0.51.0-0.5-1.20.40.81.2-1.41.91.51.61.1
Pavlov. Cond. intertrial magazine entries0.70.93.40.40.20.4-0.80.2-1.0-0.51.3-0.50.5-1.00.61.80.91.6
Pavlov. Cond. lever-magazine prob. diff.0.91.23.2-0.6-0.5-1.10.4-0.80.60.9-0.8-0.4-0.91.3-1.8-1.8-1.5-1.4
Pavlov. Cond. response bias0.70.93.0-0.6-0.4-0.60.7-0.70.80.9-1.00.1-0.61.1-1.1-1.7-1.1-1.6
Conditioned reinforcement - actives1.81.86.0-1.8-1.40.80.30.5-2.41.71.70.31.4-0.70.71.90.61.2
Conditioned reinforcement - inactives0.40.41.2-1.0-0.80.10.4-0.1-1.11.00.60.00.40.00.60.80.10.7
Conditioned locomotion1.21.45.3-1.7-1.30.70.60.4-2.31.80.70.61.3-0.20.71.50.51.2
Intermittent access intake day 1-15 change1.21.24.0-2.0-1.70.41.6-0.0-0.91.91.00.20.70.51.20.8-0.0-0.0
Intermittent access intake escalation1.01.03.5-1.9-1.60.11.2-0.1-0.71.81.3-0.10.50.40.80.8-0.10.1
Intermittent access intake escalation 21.51.43.3-1.8-1.60.51.50.1-1.61.81.2-0.00.80.21.81.50.40.6
Intermitt. access day 1 inactive lever presses0.40.41.30.00.0-1.00.0-0.50.6-0.1-0.4-0.5-1.10.7-0.5-1.1-0.8-0.6
Intermitt. access day 15 inactive lever presses0.91.02.4-0.10.0-1.10.1-1.30.20.20.3-1.1-1.41.4-1.3-1.6-1.3-1.4
Intermitt. access escalation Index3.02.76.52.52.21.3-1.21.91.5-2.5-2.51.70.9-1.50.1-0.11.40.6
Intermittent access day 1 total infusions0.60.72.4-0.7-0.60.80.20.2-1.50.60.40.71.2-0.70.61.20.60.9
Intermittent access day 15 total infusions1.61.84.0-2.0-1.80.90.90.2-1.81.81.60.51.6-0.61.11.80.50.9
Intermittent access terminal intake (last 3 days)2.02.24.8-2.2-2.01.11.40.5-2.02.01.30.91.7-0.61.61.80.60.8
Intermittent access total infusions1.11.24.1-1.2-1.01.10.50.3-2.01.10.80.81.6-0.81.01.50.70.9
Intermittent access day 1 locomotion1.21.23.6-1.0-0.81.10.40.5-1.91.00.50.81.5-0.81.41.60.81.1
Intermittent access day 15 total locomotion2.12.36.7-2.6-2.30.51.50.2-1.82.61.60.41.3-0.21.41.70.30.8
Intermittent access total locomotion1.82.15.9-2.4-2.20.61.30.2-2.22.41.40.51.3-0.11.01.50.20.7
Intermittent access standard deviation1.51.64.5-2.1-1.9-0.30.8-0.6-1.62.02.1-0.80.30.30.61.4-0.10.8
Cocaine induced anxiety0.60.73.30.50.1-0.7-0.10.11.8-0.5-0.70.1-0.70.3-1.4-1.3-0.7-0.9
Post-drug Anxiety1.71.94.50.60.2-1.8-0.3-0.81.7-0.4-0.3-1.2-2.11.2-2.1-2.1-1.6-1.4
Baseline Anxiety0.30.31.5-0.00.5-0.5-0.4-0.6-1.20.20.0-0.9-0.70.6-0.3-0.1-0.20.2
Lifetime Intake1.41.64.2-0.9-0.71.40.10.8-2.10.80.61.11.9-1.21.11.91.11.4
Incentive Sensitization - Responses0.60.63.3-0.6-0.50.70.10.2-1.80.40.70.41.0-0.50.61.00.40.6
Incentive Sensitization - Breakpoint0.60.63.0-0.6-0.50.80.10.3-1.70.50.60.41.0-0.50.61.00.50.6
Progressive ratio test 1 active lever presses0.30.41.1-0.2-0.20.6-0.20.5-1.10.1-0.30.91.0-0.70.20.60.40.7
Progressive ratio test 1 breakpoint0.50.51.3-0.4-0.40.70.10.6-1.00.4-0.31.11.2-0.70.40.70.40.7
Progressive ratio test 1 inactive lever presses0.10.10.6-0.0-0.20.00.30.60.3-0.1-0.70.70.1-0.20.3-0.20.10.2
Progressive ratio test 2 active lever presses0.91.04.2-0.9-0.70.90.00.4-2.00.81.00.51.3-0.80.81.40.60.9
Progressive ratio test 2 breakpoint1.01.14.9-0.6-0.41.1-0.20.5-2.20.60.90.51.4-0.91.01.60.81.1
Progressive ratio test 2 inactive lever presses0.40.42.7-0.7-0.40.2-0.1-0.2-1.60.70.9-0.10.5-0.20.20.90.20.6
Total sessions with >9 infusions1.41.63.80.91.01.0-1.90.8-1.8-0.9-0.40.81.3-1.60.21.51.11.9
Short access day 1 total inactive lever presses1.01.12.81.41.30.5-1.71.0-0.3-1.5-1.30.90.6-1.1-0.30.40.71.2
Short access day 10 total inactive lever presses1.11.22.8-0.4-0.4-1.40.9-1.21.00.3-0.1-1.0-1.71.4-0.5-1.6-1.2-1.4
Short access day 1 total infusions1.61.73.40.50.41.4-0.91.4-1.8-0.7-0.61.51.7-1.80.71.61.41.8
Short access day 10 total infusions1.11.23.4-1.1-0.91.00.30.7-1.91.10.60.81.5-0.80.81.70.81.4
Short access total infusions1.51.74.5-0.1-0.01.3-0.81.1-2.1-0.00.11.11.8-1.60.62.01.32.0
Short access day 1 locomotion2.42.65.8-1.2-1.11.80.91.4-2.01.10.11.82.4-1.31.82.31.51.7
Short access day 10 total locomotion0.60.62.6-0.9-0.6-0.30.0-0.6-1.61.11.1-0.80.00.40.60.8-0.10.7
Short access total locomotion1.01.14.1-0.7-0.40.5-0.7-0.0-2.00.81.3-0.31.0-0.70.61.80.61.6
Compulsive drug intake3.13.16.4-1.0-1.2-2.4-0.0-1.22.41.01.7-2.0-2.21.4-2.5-1.6-2.1-1.5
One hour access (0.3 mA shock)1.72.06.6-2.2-2.00.40.60.2-1.62.12.6-0.11.1-0.60.82.00.31.0
One hour access (shock baseline)2.73.27.2-1.1-0.92.20.81.3-2.51.10.51.92.7-1.62.42.51.71.5
Number of responses in last shaping day2.92.99.1-1.8-1.91.61.80.8-2.51.50.81.42.1-0.83.02.01.00.9
Context. condit. distance diff. score1.72.17.7-2.7-2.00.42.3-0.7-0.92.81.2-0.00.51.01.60.3-0.3-0.9
Locomotion velocity, session 10.10.10.20.2-0.4-0.30.2-0.0-0.1-0.40.1-0.2-0.10.2-0.50.2-0.20.4
Locomotion distance, session 10.20.30.90.90.6-0.3-0.2-0.00.5-0.9-0.90.0-0.40.3-0.4-0.7-0.2-0.2
Locomotion velocity, session 20.30.41.61.10.5-0.5-0.70.1-0.2-1.3-0.2-0.3-0.5-0.1-0.8-0.1-0.20.5
Locomotion distance, session 20.81.25.01.81.50.1-0.70.90.4-2.0-2.20.8-0.3-0.2-0.4-0.90.20.1
Locomotion velocity, session 30.30.31.80.60.6-0.4-1.4-0.5-0.4-0.60.7-0.8-0.2-0.0-0.20.3-0.10.6
Locomotion distance, session 30.60.72.10.60.90.5-1.40.3-1.4-0.6-0.1-0.00.6-0.80.41.00.71.3
Stereotopy head waving bouts, day 30.40.41.40.50.3-1.1-0.4-0.21.0-0.4-0.0-0.9-1.20.3-0.7-0.5-0.60.1
Stereotopy head waving duration, day 31.01.23.4-0.7-0.9-1.80.3-1.10.20.91.0-1.7-1.51.3-1.0-0.6-1.4-0.3
Locomotion velocity, session 70.10.10.5-0.10.1-0.2-0.3-0.7-0.50.30.4-0.5-0.20.4-0.5-0.2-0.3-0.3
Locomotion distance, session 70.60.82.5-0.9-0.41.10.00.3-1.60.80.20.81.5-0.70.81.20.80.8
Stereotopy head waving bouts, day 70.40.51.60.20.5-1.0-0.7-0.30.4-0.00.5-1.1-1.30.3-1.2-0.5-0.5-0.1
Stereotopy head waving duration, day 70.50.62.40.20.3-1.3-0.4-0.50.6-0.10.6-1.3-1.60.5-1.1-0.6-0.7-0.1
Locomotion velocity, session 80.40.51.90.60.40.40.70.81.0-0.7-1.41.00.10.10.5-0.60.3-0.5
Locomotion distance, session 80.60.83.6-1.3-0.90.51.9-0.1-0.31.2-0.50.70.30.91.3-0.5-0.2-1.0
Degree of sensitization distance1.31.33.9-2.0-1.8-0.21.8-0.70.11.90.60.10.11.0-0.5-0.5-0.8-1.3
Degree of sensitization stereotypy0.10.10.50.20.7-0.2-0.50.20.1-0.10.2-0.4-0.6-0.3-0.5-0.10.10.1
Condit. Reinf. active minus inactive responses2.32.69.2-0.3-0.1-1.8-0.8-2.00.00.41.1-2.0-1.91.7-3.0-1.8-1.9-1.6
Condit. Reinf. active-inactive response ratio3.53.810.8-0.50.1-2.3-0.8-2.30.80.90.8-2.3-2.62.1-3.3-2.5-2.4-2.1
Condit. Reinf. active responses0.50.63.3-0.0-0.0-0.8-0.7-1.0-0.50.10.9-1.0-0.70.7-1.8-0.5-0.8-0.5
Condit. Reinf. inactive responses1.72.03.61.00.71.9-0.41.5-1.1-1.3-0.71.51.9-1.51.51.81.81.7
Incentive salience index mean2.63.19.7-0.2-0.3-2.2-0.4-2.00.80.21.0-2.1-2.31.9-3.1-2.2-2.2-1.9
Condit. Reinf. lever presses1.62.25.20.2-0.1-1.80.2-1.01.7-0.30.1-1.2-2.11.5-2.2-2.3-1.8-1.9
Time in familiar zone, hab. session 12.32.24.4-1.5-1.3-1.31.1-1.71.01.40.8-1.2-1.32.0-1.2-1.7-1.8-2.1
Time in novel zone, hab. session 10.30.31.20.40.30.1-0.50.6-0.2-0.30.10.20.3-0.80.50.90.61.1
Total zone transitions, hab. session 10.60.92.81.21.7-0.2-1.6-0.70.1-0.9-1.1-0.3-0.50.5-1.1-1.3-0.5-0.6
Total locomotion distance, hab. session 10.20.31.40.91.20.1-1.1-0.20.3-0.8-0.6-0.0-0.1-0.1-0.5-0.6-0.0-0.3
Locomotion velocity, hab. session 10.40.62.31.31.50.2-1.2-0.00.2-1.3-0.90.1-0.2-0.2-0.4-0.70.1-0.2
Time in familiar zone, hab. session 20.10.10.4-0.00.10.10.40.10.3-0.0-0.40.2-0.00.20.6-0.30.1-0.4
Time in novel zone, hab. session 21.11.12.4-1.2-1.2-1.20.5-1.00.41.41.2-1.0-0.90.8-1.6-0.5-1.1-0.7
Total zone transitions, hab. session 21.11.44.01.92.00.7-1.80.5-1.1-1.6-1.60.40.5-0.60.30.40.81.3
Total locomotion distance, hab. session 20.70.92.91.71.70.2-1.50.4-0.3-1.5-1.40.20.0-0.5-0.3-0.10.40.8
Locomotion velocity, hab. session 21.01.33.82.01.90.5-1.80.5-0.6-1.8-1.40.30.3-0.80.00.30.71.2
Novel to familiar place preference ratio0.30.30.7-0.4-0.2-0.50.3-0.60.60.60.6-0.6-0.70.5-0.6-0.6-0.6-0.8
Novelty place preference0.70.71.2-0.9-0.7-0.80.7-0.80.81.10.9-0.9-0.90.9-0.6-0.8-0.9-1.1
Time in novel zone, NPP test1.11.22.4-1.3-1.0-1.00.9-1.20.71.61.2-1.0-1.01.1-0.8-0.9-1.1-1.3
Total zone transitions, NPP test0.40.61.4-0.4-0.4-1.00.2-1.2-0.10.60.4-1.1-0.91.2-0.8-0.6-1.0-0.3
Total locomotion distance, NPP test0.00.00.1-0.0-0.0-0.00.1-0.3-0.30.10.1-0.2-0.00.3-0.00.1-0.00.1
Locomotion velocity, NPP test0.00.10.20.40.30.1-0.10.1-0.2-0.3-0.2-0.10.0-0.00.20.30.20.5
Pavlov. Cond. lever latency0.30.32.4-0.4-0.40.10.60.20.90.70.00.10.2-0.11.60.50.40.5
Pavlov. Cond. magazine entry latency1.41.85.9-0.2-0.2-1.20.7-0.81.60.1-0.6-0.4-1.51.5-1.9-2.4-1.6-2.2
Pavlov. Cond. change in total contacts0.30.32.00.50.4-0.2-0.10.30.5-0.7-0.40.3-0.4-0.0-1.4-0.9-0.3-0.7
Pavlov. Cond. index score0.60.73.00.10.2-0.50.1-0.50.4-0.3-0.4-0.1-0.80.8-1.7-1.6-1.0-1.5
Pavlov. Cond. latency score0.70.93.5-0.00.0-0.70.1-0.70.2-0.1-0.3-0.3-0.91.0-1.9-1.7-1.2-1.6
Pavlov. Cond. lever contacts0.30.42.50.20.1-0.2-0.2-0.2-0.7-0.5-0.30.1-0.20.4-1.6-0.9-0.6-0.8
Pavlov. Cond. magazine entry number1.31.75.00.20.11.2-0.50.8-1.4-0.10.20.61.6-1.32.12.21.52.2
Pavlov. Cond. intertrial magazine entries1.01.25.2-0.30.01.0-0.70.6-2.30.40.70.41.3-1.10.91.81.11.6
Pavlov. Cond. lever-magazine prob. diff.0.50.62.60.30.3-0.40.0-0.30.3-0.5-0.50.0-0.70.6-1.6-1.5-0.8-1.4
Pavlov. Cond. response bias0.81.03.60.20.1-0.80.3-0.30.9-0.5-0.5-0.1-1.10.8-1.9-1.8-1.0-1.6
Bone: apparent density1.83.05.51.91.42.2-0.62.0-0.2-2.1-1.62.32.1-2.11.11.32.21.3
Bone surface0.50.91.51.20.91.2-0.70.8-0.1-1.2-0.61.01.1-1.20.30.81.20.8
Bone volume0.81.42.91.30.81.6-0.21.30.3-1.3-1.01.71.5-1.40.80.91.50.7
Bone: connectivity density1.11.73.80.90.71.6-0.21.8-0.0-1.1-1.41.91.7-1.61.01.21.71.2
Bone: cortical apparent density0.20.30.8-0.5-0.7-0.70.4-0.60.30.20.9-0.9-0.60.5-0.00.0-0.4-0.2
Bone: cortical area0.10.20.5-0.3-0.3-0.20.3-0.7-0.30.70.4-0.5-0.20.6-0.1-0.0-0.3-0.2
Bone: cortical porosity2.02.23.1-1.3-1.7-1.71.5-1.21.61.21.8-1.4-1.71.4-0.9-1.1-1.5-1.6
Bone: cortical porosity1.21.33.4-1.0-1.4-1.31.3-1.01.00.91.8-1.3-1.31.0-0.3-0.5-1.1-1.1
Bone: cortical thickness0.81.32.6-1.2-1.2-1.20.9-1.40.11.51.6-1.5-1.11.3-0.3-0.4-1.1-0.8
Bone: cortical thickness0.40.41.50.3-0.1-0.6-0.3-1.00.1-0.11.1-1.0-0.60.5-1.2-0.1-0.6-0.3
Bone: cortical tissue density0.20.20.7-0.4-0.6-0.60.4-0.50.40.20.9-0.8-0.60.5-0.0-0.0-0.4-0.2
Bone: elastic displacement1.82.14.91.92.21.5-2.00.5-1.9-2.0-0.20.51.2-1.60.21.11.41.0
Bone: elastic work1.62.13.81.61.51.8-1.11.0-1.9-1.6-1.01.21.7-1.61.01.31.61.3
Bone: endosteal estimation0.40.81.50.90.51.2-0.21.0-0.4-0.9-0.71.11.2-1.10.70.91.10.8
Bone: endosteal perimeter0.81.73.51.91.91.4-1.51.0-0.6-1.7-1.91.21.2-1.10.10.51.21.0
Bone: final force0.81.34.3-1.6-2.1-0.71.7-0.9-0.41.71.8-0.9-0.30.9-0.20.3-0.8-0.5
Bone: final moment0.71.24.0-1.6-2.0-0.51.6-0.8-0.41.71.7-0.7-0.10.7-0.20.4-0.6-0.5
Bone: marrow area0.40.81.40.90.61.2-0.30.9-0.4-0.9-0.71.11.2-1.00.60.91.10.8
Bone: maximum diameter0.40.82.61.61.40.6-1.00.5-0.5-1.1-1.40.50.4-0.50.10.20.70.8
Bone: maximum force0.61.02.3-1.2-1.50.51.40.3-0.91.41.10.30.9-0.21.01.40.50.5
Bone: maximum moment0.50.92.2-1.2-1.50.61.40.2-0.91.31.10.31.0-0.30.91.40.50.5
Bone: minimum diameter0.30.61.3-1.0-0.90.70.90.2-1.01.20.40.41.0-0.20.91.00.50.5
Bone: periosteal estimation0.10.30.60.60.30.8-0.00.4-0.4-0.4-0.30.50.8-0.50.50.70.70.5
Bone: periosteal perimeter0.30.51.51.11.20.3-1.20.1-0.6-0.8-1.00.20.3-0.3-0.70.00.30.6
Bone: post-yield work0.10.20.7-0.5-0.10.40.50.20.00.6-0.50.50.40.00.90.20.40.1
Bone: stiffness0.61.02.4-1.0-1.20.81.40.80.01.20.30.81.1-0.41.51.30.80.8
Bone: tissue strength1.11.11.90.91.31.2-1.01.0-0.7-0.8-1.01.01.0-1.20.71.01.41.2
Bone: trabecular number1.52.33.61.51.61.8-1.41.6-0.6-1.7-1.11.51.7-1.80.71.41.91.6
Bone: trabecular spacing0.50.61.0-0.7-0.8-0.80.7-1.00.70.80.6-0.7-0.80.8-0.7-0.8-1.0-1.0
Bone: trabecular thickness2.12.64.61.61.32.1-0.91.7-0.9-1.6-1.32.02.1-1.91.11.42.01.4
Bone: trabecular tissue density0.81.24.50.60.8-0.5-2.1-1.2-1.5-0.41.4-1.7-0.40.0-0.90.8-0.11.1
Breakpoint value in progressive ratio session8.29.117.11.10.83.80.23.7-2.5-1.5-2.44.14.1-3.53.33.43.73.2
Distance traveled before self-admin0.50.52.20.30.4-0.9-0.5-1.3-0.8-0.10.5-1.5-0.91.0-0.3-0.1-0.50.0
Distance traveled after self-admin1.41.54.0-0.7-0.9-1.7-0.3-1.6-0.70.81.8-2.0-1.31.1-1.5-0.4-1.5-0.4
Delta time in closed arm before/after self-admin1.00.92.7-1.6-1.5-0.31.6-0.3-0.61.51.2-0.4-0.10.61.00.5-0.2-0.1
Delta time in open arm before/after self-admin0.80.82.51.51.30.4-0.70.90.7-1.4-1.60.70.0-0.5-0.0-0.50.50.1
Diff in mean of infusions in LGA sessions1.61.83.21.51.51.7-0.91.1-1.6-1.8-1.51.61.5-1.40.00.51.30.6
Extinction: sum of active levers before priming1.11.12.70.30.41.3-0.31.7-0.3-0.3-0.91.41.4-1.30.41.31.41.4
Active lever presses in extinction session 62.52.44.9-1.0-1.21.61.41.3-2.10.80.21.52.1-1.22.22.21.41.5
Delta distance traveled before/after self-admin0.50.52.3-1.0-1.1-0.40.1-0.00.00.91.1-0.0-0.0-0.1-1.5-0.2-0.7-0.6
Delta ambulatory time before/after self-admin0.30.41.3-0.9-1.2-0.30.30.10.10.80.70.20.1-0.1-1.1-0.3-0.7-0.6
Time in closed arm before self-admin0.10.10.30.40.3-0.1-0.5-0.10.4-0.50.4-0.2-0.2-0.3-0.00.0-0.00.1
Time in closed arm after self-admin0.90.92.5-1.1-1.5-0.81.6-0.81.01.11.2-0.6-0.60.70.7-0.3-0.8-0.9
Time in open arm before self-admin0.30.31.3-1.0-0.70.41.10.0-0.60.9-0.20.50.40.40.60.00.1-0.4
Time in open arm after self-admin1.51.63.51.41.51.5-0.81.2-1.2-1.4-1.91.41.2-1.11.10.61.40.9
Sum of active levers in priming session hrs 5-60.90.92.4-0.6-0.71.00.61.3-1.10.5-0.71.61.4-0.80.40.90.70.8
Time to tail flick, vehicle, before self-admin0.90.93.91.31.4-0.3-2.0-0.2-0.8-1.2-0.0-0.8-0.3-0.4-0.60.50.31.3
Time to tail flick, vehicle, after self-admin0.40.41.9-0.0-0.3-0.11.00.31.4-0.1-1.20.8-0.10.30.1-0.9-0.3-0.7
Time to tail flick, test, before self-admin0.20.20.4-0.6-0.5-0.40.5-0.3-0.20.30.4-0.2-0.30.4-0.3-0.4-0.5-0.6
Time to tail flick, test, after self-admin0.80.82.01.01.10.4-0.71.40.7-1.2-1.31.00.2-1.0-0.10.10.80.7
Delta time to tail flick, vehicle, before/after SA1.11.13.6-0.8-0.9-0.71.4-0.21.90.7-0.50.3-0.70.9-0.7-1.5-1.0-1.5
Delta time to tail flick, test, before/after SA1.61.53.01.71.70.6-1.71.30.9-1.6-1.20.80.4-1.4-0.30.51.21.3
Ambulatory time before self-admin0.30.31.10.20.4-0.6-0.3-0.9-0.4-0.10.1-1.0-0.70.8-0.1-0.1-0.30.1
Ambulatory time after self-admin0.60.61.7-1.0-1.1-0.90.1-0.6-0.71.11.3-1.0-0.50.6-0.60.2-0.80.1
Total heroin consumption4.65.511.61.41.32.5-1.32.9-1.9-1.6-1.62.52.8-2.91.82.92.93.4
Area under the delay curve1.31.44.21.30.90.8-1.41.0-0.7-1.2-0.20.51.0-1.50.81.61.32.0
Delay disc. indifference point, 0s delay1.01.13.70.40.20.8-1.10.6-0.9-0.50.80.11.1-1.40.81.91.11.8
Delay disc. indifference point, 16s delay0.10.10.5-0.3-0.6-0.20.10.20.10.30.5-0.10.1-0.3-0.10.60.10.7
Delay disc. indifference point, 2s delay2.52.88.20.50.41.6-0.81.1-2.5-0.50.40.82.0-1.92.02.91.92.6
Delay disc. indifference point, 24s delay0.50.52.01.41.0-0.2-1.00.10.4-1.4-0.5-0.2-0.4-0.4-0.3-0.10.10.5
Delay disc. indifference point, 4s delay1.01.12.21.41.10.8-1.30.8-0.3-1.4-0.10.30.7-1.30.81.21.11.5
Delay disc. indifference point, 8s delay1.81.85.41.71.30.8-1.71.2-0.7-1.6-0.70.51.0-1.60.61.61.42.3
Delay discount exponential model param1.41.54.2-1.4-1.1-0.91.5-1.10.81.30.3-0.5-1.01.5-0.8-1.6-1.3-2.1
Delay discount hyperbolic model param1.51.64.6-1.3-1.0-1.01.4-1.10.91.30.2-0.5-1.21.6-1.0-1.8-1.4-2.1
Fecal boli incidents, locomotor time 10.60.72.71.41.20.4-0.60.60.2-1.3-1.70.70.2-0.4-0.1-0.40.40.1
Change in fecal boli incidents, locomotor task0.30.21.10.50.60.1-1.1-0.5-0.3-0.50.6-0.50.1-0.3-0.70.20.00.1
Time >=10cm from walls, locomotor time 11.61.65.11.21.4-1.3-1.8-0.91.6-1.1-0.2-1.4-1.50.6-2.3-1.1-0.7-0.1
Bouts of movement, locomotor time 10.20.20.7-0.8-0.50.30.4-0.3-0.60.80.8-0.10.40.10.50.40.1-0.2
Total resting periods, locomotor time 10.40.41.1-1.1-0.70.50.8-0.4-0.91.01.00.00.60.10.80.50.1-0.3
Rest time, locomotor task time 12.22.47.1-0.4-0.42.31.41.70.00.2-1.22.42.3-1.22.71.41.80.6
Distance moved, locomotor task time 12.93.27.4-0.4-0.4-2.5-0.7-2.30.60.51.8-2.7-2.51.8-2.7-1.5-2.1-1.1
Vertical activity count, locomotor time 10.91.02.80.3-0.0-1.4-0.7-1.00.4-0.11.3-1.7-1.40.7-1.4-0.5-1.0-0.3
Time >=10cm from walls, locomotor time 20.90.92.31.51.4-0.5-1.4-0.31.3-1.4-0.8-0.5-0.70.1-1.3-0.7-0.10.0
Bouts of movement, locomotor time 20.20.30.80.30.4-0.6-0.7-0.5-0.9-0.2-0.0-0.7-0.60.3-0.5-0.3-0.50.2
Total resting periods, locomotor time 20.30.30.60.30.4-0.8-0.8-0.6-0.8-0.3-0.0-0.8-0.70.3-0.6-0.4-0.60.1
Rest time, locomotor task time 20.80.92.90.20.41.1-0.30.9-0.6-0.2-0.30.81.2-1.01.71.41.21.3
Distance moved, locomotor task time 21.11.32.4-0.5-0.7-1.50.2-1.40.80.51.1-1.5-1.51.3-1.5-1.1-1.4-1.2
Vertical activity count, locomotor time 20.30.31.2-0.5-0.8-0.41.1-0.30.40.50.2-0.2-0.40.7-0.1-0.5-0.6-0.8
Weight adjusted by age0.60.62.20.30.70.6-1.10.7-1.1-0.20.00.20.6-0.90.61.20.91.5
Seeking ratio, delayed vs. immediate footshock0.50.52.8-0.9-0.60.50.30.2-1.70.80.20.30.8-0.10.90.90.30.7
Locomotion in novel chamber1.01.26.01.21.00.6-0.51.60.7-1.2-2.41.70.5-0.9-0.5-0.50.60.5
Locomotion in novel chamber post-restriction0.60.82.1-0.2-0.3-1.10.50.21.50.1-1.0-0.1-1.10.8-1.1-1.5-0.9-0.8
Progressive ratio2.73.15.01.41.42.1-0.91.8-0.6-1.4-2.02.12.0-2.02.21.52.12.0
Food seeking constrained by brief footshock5.16.213.30.70.83.3-0.52.7-2.8-0.8-1.22.93.6-2.92.73.13.02.7
Seeking ratio, punishment vs. effort0.81.03.5-1.4-1.3-0.60.8-0.8-0.91.31.9-1.0-0.40.7-0.70.2-0.7-0.6
Run reversals in cocaine runway, females1.51.54.42.01.90.2-1.41.00.3-2.0-2.10.7-0.2-0.8-1.3-0.70.40.3
Run reversals in cocaine runway, males0.10.10.30.2-0.4-0.40.50.30.6-0.1-0.3-0.1-0.30.40.4-0.0-0.20.3
Latency to leave start box in cocaine runway1.21.35.71.00.9-1.4-1.5-0.80.7-0.90.2-1.4-1.50.6-2.4-0.9-0.9-0.1
Latency to leave start box in cocaine runway, F1.61.74.3-0.2-0.2-1.8-0.6-1.60.20.30.9-2.0-1.81.4-2.1-1.2-1.7-0.9
Latency to leave start box in cocaine runway, M2.92.88.02.82.60.9-2.61.10.6-2.8-1.20.70.6-1.7-0.90.71.41.4
Cd content in liver1.41.66.3-1.6-2.1-0.42.5-0.81.01.20.40.0-0.21.40.8-0.9-1.0-1.7
Co content in liver0.70.84.1-0.5-0.21.31.0-0.1-1.00.70.30.71.2-0.32.00.80.8-0.1
Cu content in liver0.80.93.3-0.9-0.70.70.30.1-1.10.91.6-0.11.0-0.81.01.80.81.0
Fe content in liver0.50.62.2-1.1-1.5-0.41.5-0.00.90.80.50.2-0.20.4-0.5-0.4-0.5-0.9
K content in liver1.01.03.11.21.20.1-1.11.30.1-1.3-1.00.4-0.0-1.20.60.81.01.7
Mg content in liver0.20.20.90.20.1-0.6-0.50.2-0.3-0.40.5-0.6-0.4-0.3-0.10.60.10.9
Mn content in liver0.10.10.3-0.3-0.4-0.10.3-0.5-0.50.10.5-0.2-0.00.2-0.20.1-0.1-0.1
Na content in liver0.50.51.80.80.7-0.6-0.80.31.1-1.0-0.2-0.2-0.8-0.3-1.3-0.4-0.10.2
Rb content in liver0.20.21.0-0.7-0.7-0.40.1-0.4-0.20.31.0-0.6-0.20.1-0.10.5-0.10.3
Se content in liver0.91.13.8-1.8-1.9-0.31.7-0.2-0.21.51.5-0.40.10.30.50.7-0.2-0.0
Sr content in liver1.11.02.41.31.60.8-1.41.0-0.2-1.1-1.50.90.6-1.00.20.30.91.0
Zn content in liver0.30.31.0-1.0-0.7-0.50.7-0.30.41.0-0.4-0.2-0.30.70.5-0.2-0.40.0