Eml2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000030127 0.27 0.22 2.0e-03 0.02 0.03 0.02 0.02 1.7e-03 5.8e-04 2.6e-03 1.5e-03
2 Liver gene expression ENSRNOG00000030127 0.09 0.08 4.8e-07 0.05 0.05 0.05 0.05 3.0e-06 2.0e-06 3.1e-06 2.8e-06
3 Liver isoform ratio ENSRNOT00000078336 0.14 0.16 3.3e-03 0.01 0.01 0.01 0.01 1.0e-02 8.5e-03 7.5e-03 7.2e-03
4 Liver isoform ratio ENSRNOT00000115540 0.02 0.02 5.4e-03 0.01 0.01 0 0 5.3e-02 5.5e-02 3.1e-01 1.9e-01
5 Liver mRNA stability ENSRNOG00000030127 0.35 0.16 0.0e+00 0.15 0.16 0.17 0.16 1.8e-16 6.3e-18 5.3e-18 1.3e-17
6 NAcc alternative TSS ENSRNOT00000111912 0.05 0.05 5.3e-04 0.03 0.03 0.04 0.03 2.2e-03 2.9e-03 1.2e-03 3.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
BMI with tail0.72.43.2-1.8-1.51.5-1.5-1.3-1.7
BMI without tail1.32.73.6-1.9-1.51.5-1.4-1.6-1.8
Body weight1.04.15.2-2.3-1.91.9-1.7-1.9-2.3
Epididymis fat weight0.71.62.40.81.3-1.61.41.31.1
Glucose0.20.30.40.50.6-0.60.60.40.7
Heart weight2.84.05.7-1.6-2.02.4-2.0-2.0-1.9
Left kidney weight7.621.926.5-4.4-4.65.1-4.6-4.4-4.9
Right kidney weight6.117.320.3-3.8-4.14.5-4.1-4.1-4.3
Tail length0.10.20.3-0.5-0.30.3-0.2-0.5-0.5
Length with tail0.20.81.0-0.9-0.80.9-0.7-0.8-1.0
Length without tail0.10.20.4-0.4-0.50.6-0.5-0.4-0.5
Liver weight, left10.416.818.7-3.9-4.04.2-3.9-4.3-4.3
Liver weight, right2.33.84.9-2.0-1.92.0-1.7-1.9-2.2
Parametrial fat weight0.10.10.1-0.3-0.30.3-0.3-0.3-0.4
Retroperitoneal fat weight0.00.10.10.10.2-0.30.30.30.1
Intraocular pressure0.00.00.00.20.10.00.10.10.2
Extensor digitorum longus weight1.56.17.5-2.2-2.42.6-2.4-2.4-2.7
Soleus weight0.10.20.3-0.4-0.40.6-0.4-0.4-0.5
Tibialis anterior weight3.211.113.6-3.0-3.33.7-3.3-3.1-3.6
Tibia length0.41.01.8-1.3-1.01.0-1.0-0.8-0.9
Number of licking bursts3.54.24.8-2.2-2.01.9-2.0-2.0-2.0
Food consumed during 24 hour testing period5.97.18.12.62.6-2.92.72.52.7
Times rat made contact with spout0.00.00.10.30.1-0.10.2-0.10.0
Mean time between licks in bursts0.10.10.10.20.2-0.30.30.40.3
Mean num. licks in bursts3.64.35.52.42.0-2.02.11.92.0
Std. dev. time between licks in bursts0.00.00.0-0.1-0.00.00.10.0-0.2
Water consumed over 24 hours0.20.20.30.50.5-0.50.60.30.4
Indifference point 0 sec0.30.50.9-0.5-0.70.9-0.8-0.8-0.6
Indifference point AUC3.74.44.7-2.2-2.02.1-2.0-2.0-2.2
Indifference point function ln k1.31.82.71.71.2-1.31.31.01.4
Indifference point function log k1.31.82.71.71.2-1.31.31.01.4
Delay discounting total patch changes 0 sec0.50.81.2-0.5-0.91.1-0.9-1.0-0.8
Delay discounting total patch changes 12 sec1.62.12.6-1.6-1.41.5-1.4-1.3-1.5
Delay discounting total patch changes 18 sec2.22.93.4-1.5-1.61.8-1.6-1.8-1.8
Delay discounting total patch changes 24 sec0.30.30.5-0.7-0.60.5-0.5-0.4-0.7
Delay discounting total patch changes 6 sec2.33.54.5-1.8-1.92.1-1.9-1.7-1.8
Delay discounting time to switch 0 sec3.96.06.92.32.4-2.62.32.52.6
Delay discounting water rate 0 sec4.26.77.8-2.5-2.62.8-2.4-2.5-2.7
Delay discounting water rate 12 sec0.20.30.4-0.4-0.50.6-0.4-0.6-0.6
Delay discounting water rate 18 sec0.10.10.2-0.2-0.30.4-0.2-0.4-0.4
Delay discounting water rate 24 sec0.70.91.4-0.8-0.90.9-0.8-1.2-1.0
Delay discounting water rate 6 sec0.71.01.4-1.0-1.01.0-0.8-1.1-1.2
Locomotor activity2.43.84.7-1.7-1.92.2-2.0-2.0-1.9
Locomotor testing distance0.81.31.8-0.9-1.11.4-1.2-1.1-1.1
Locomotor testing rearing5.79.09.8-3.1-2.93.1-2.9-2.8-3.1
Light reinforcement 10.00.00.2-0.0-0.20.4-0.2-0.1-0.2
Light reinforcement 20.00.10.1-0.3-0.20.3-0.20.1-0.3
Reaction time number correct5.47.79.2-2.4-2.73.0-2.7-2.9-2.8
Reaction time mean minus median0.20.30.90.90.5-0.30.30.30.7
Reaction time mean minus median AUC0.10.10.20.2-0.30.4-0.4-0.4-0.1
Reaction time num false alarms4.36.07.0-2.5-2.42.5-2.3-2.3-2.6
Reaction time num false alarms AUC3.55.05.7-2.3-2.22.3-2.1-2.1-2.4
Reaction time trials correct on left5.47.79.2-2.4-2.73.0-2.7-2.9-2.8
Reaction time trials on left5.47.69.2-2.4-2.73.0-2.7-2.9-2.8
Reaction time mean1.72.43.31.81.5-1.41.41.41.7
Reaction time mean AUC1.52.03.11.81.3-1.31.21.31.5
Median of all reaction times2.22.93.41.91.7-1.71.61.71.8
Reaction time omissions0.00.00.10.0-0.10.2-0.20.2-0.1
Reaction time false alarm rate0.10.10.3-0.6-0.30.3-0.3-0.2-0.4
Reaction time premature initiation rate0.50.70.80.70.8-0.80.80.80.9
Reaction time premature initiations0.20.30.5-0.3-0.60.7-0.5-0.6-0.5
Std. dev. reaction times0.50.61.41.20.7-0.60.50.70.9
Reaction time trials completed5.47.69.2-2.4-2.73.0-2.7-2.9-2.8
Reaction time trials AUC6.59.411.1-2.7-3.03.3-3.0-3.2-3.1
Social response proportion0.80.91.3-0.7-1.01.2-1.0-0.9-1.0
Social responses0.60.71.1-0.7-0.91.1-0.9-0.7-0.8
Social time4.76.17.62.42.3-2.42.32.82.7
Conditioned locomotion0.00.00.10.10.2-0.20.20.00.1
Cocaine response after cond. corrected0.50.60.9-0.6-0.80.9-0.9-0.6-0.8
Cocaine response after cond. not corrected1.51.62.1-1.1-1.31.5-1.3-1.1-1.3
Cocaine response before conditioning1.82.22.5-1.6-1.41.5-1.4-1.4-1.6
Saline control response1.82.42.8-1.4-1.51.6-1.5-1.7-1.6
Condit. Reinf. active minus inactive responses0.10.10.2-0.4-0.30.3-0.3-0.4-0.4
Condit. Reinf. active-inactive response ratio0.60.60.8-0.6-0.70.8-0.7-0.9-0.8
Condit. Reinf. active responses0.10.10.10.10.3-0.40.30.30.3
Condit. Reinf. inactive responses0.81.01.20.81.0-1.11.01.11.1
Condit. Reinf. lever presses0.30.40.5-0.6-0.60.7-0.6-0.6-0.6
Condit. Reinf. lever reinforcers received0.10.10.10.20.3-0.40.30.40.4
Pavlov. Cond. lever latency0.00.00.00.10.0-0.00.1-0.0-0.0
Pavlov. Cond. magazine entry latency0.00.00.00.0-0.10.2-0.00.0-0.1
Pavlov. Cond. change in total contacts0.20.30.40.60.5-0.60.50.50.6
Pavlov. Cond. index score0.00.00.10.20.2-0.10.20.20.2
Pavlov. Cond. latency score0.10.10.10.30.3-0.20.30.40.3
Pavlov. Cond. lever contacts0.20.20.3-0.5-0.50.5-0.5-0.4-0.5
Pavlov. Cond. magazine entry number0.60.70.9-0.8-0.80.8-0.8-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.2-0.10.1-0.1-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.1-0.00.1-0.00.00.0
Pavlov. Cond. response bias0.00.00.0-0.1-0.10.1-0.1-0.1-0.1
Conditioned reinforcement - actives0.90.91.2-1.1-1.00.8-0.9-1.0-1.0
Conditioned reinforcement - inactives0.70.81.4-1.2-0.90.8-0.9-0.6-0.9
Conditioned locomotion3.13.74.3-1.9-1.91.9-1.8-2.1-2.0
Intermittent access intake day 1-15 change0.30.30.5-0.5-0.50.7-0.5-0.6-0.7
Intermittent access intake escalation0.40.40.6-0.4-0.50.8-0.5-0.6-0.7
Intermittent access intake escalation 20.60.51.0-0.3-0.51.0-0.6-0.9-0.8
Intermitt. access day 1 inactive lever presses0.10.10.3-0.5-0.50.1-0.5-0.2-0.1
Intermitt. access day 15 inactive lever presses0.40.50.9-0.9-0.70.2-0.6-0.7-0.7
Intermitt. access escalation Index0.20.20.30.30.4-0.40.50.60.4
Intermittent access day 1 total infusions0.91.01.6-1.3-1.10.8-1.0-0.8-0.9
Intermittent access day 15 total infusions0.80.91.2-1.0-0.90.8-0.8-1.0-1.1
Intermittent access terminal intake (last 3 days)1.11.21.4-1.2-1.11.0-1.1-1.1-1.1
Intermittent access total infusions2.02.32.7-1.7-1.51.3-1.5-1.5-1.5
Intermittent access day 1 locomotion0.20.20.2-0.5-0.50.4-0.5-0.5-0.4
Intermittent access day 15 total locomotion0.60.61.0-0.5-0.70.8-0.7-1.0-0.8
Intermittent access total locomotion1.82.12.4-1.4-1.51.4-1.5-1.5-1.4
Intermittent access standard deviation0.50.60.8-0.6-0.70.8-0.8-0.9-0.8
Cocaine induced anxiety1.31.52.31.01.1-1.51.11.11.3
Post-drug Anxiety0.30.40.70.30.4-0.70.30.80.8
Baseline Anxiety0.40.50.8-0.4-0.70.9-0.8-0.6-0.5
Lifetime Intake1.71.92.5-1.6-1.41.2-1.4-1.3-1.3
Incentive Sensitization - Responses0.20.20.6-0.8-0.40.3-0.4-0.2-0.5
Incentive Sensitization - Breakpoint0.20.20.6-0.7-0.40.2-0.3-0.2-0.5
Progressive ratio test 1 active lever presses0.80.81.2-1.1-1.00.9-1.0-0.7-0.8
Progressive ratio test 1 breakpoint0.50.60.8-0.9-0.80.7-0.8-0.5-0.6
Progressive ratio test 1 inactive lever presses0.40.50.7-0.8-0.80.6-0.8-0.5-0.6
Progressive ratio test 2 active lever presses0.40.40.9-1.0-0.60.4-0.6-0.5-0.7
Progressive ratio test 2 breakpoint0.30.30.8-0.9-0.60.3-0.5-0.4-0.6
Progressive ratio test 2 inactive lever presses0.10.10.3-0.5-0.1-0.2-0.00.3-0.2
Total sessions with >9 infusions3.03.34.1-2.0-1.91.7-1.8-1.6-1.7
Short access day 1 total inactive lever presses1.71.82.5-1.6-1.31.2-1.3-1.1-1.4
Short access day 10 total inactive lever presses0.50.50.60.80.8-0.80.70.70.7
Short access day 1 total infusions1.11.11.3-1.1-1.01.1-1.0-1.0-1.1
Short access day 10 total infusions2.22.43.2-1.8-1.71.3-1.6-1.5-1.4
Short access total infusions0.50.61.0-1.0-0.80.6-0.7-0.6-0.7
Short access day 1 locomotion1.11.21.4-1.1-1.11.1-1.0-1.1-1.2
Short access day 10 total locomotion0.00.00.10.20.10.20.1-0.1-0.1
Short access total locomotion0.10.10.2-0.4-0.40.2-0.3-0.3-0.3
Compulsive drug intake0.10.10.30.30.0-0.40.00.30.6
One hour access (0.3 mA shock)0.00.00.00.20.2-0.10.20.10.1
One hour access (shock baseline)1.72.02.6-1.4-1.21.4-1.2-1.5-1.6
Number of responses in last shaping day4.14.25.6-1.9-1.92.1-1.8-2.3-2.4
Context. condit. distance diff. score0.20.20.4-0.4-0.40.4-0.3-0.7-0.5
Locomotion velocity, session 10.00.00.10.00.1-0.20.0-0.20.0
Locomotion distance, session 10.00.00.20.1-0.10.2-0.1-0.4-0.2
Locomotion velocity, session 21.51.71.9-1.4-1.31.3-1.3-1.3-1.3
Locomotion distance, session 20.20.30.4-0.4-0.60.7-0.5-0.6-0.6
Locomotion velocity, session 30.20.30.4-0.6-0.50.6-0.4-0.5-0.6
Locomotion distance, session 31.01.01.21.01.0-1.01.01.11.0
Stereotopy head waving bouts, day 31.21.41.7-1.3-1.11.2-1.2-1.2-1.2
Stereotopy head waving duration, day 31.01.31.5-1.1-1.11.1-1.1-1.2-1.1
Locomotion velocity, session 70.20.30.40.60.5-0.40.60.40.5
Locomotion distance, session 70.00.00.00.1-0.00.20.10.0-0.1
Stereotopy head waving bouts, day 71.01.11.5-1.1-1.00.9-1.1-1.2-1.1
Stereotopy head waving duration, day 71.01.21.5-1.2-1.00.9-1.1-1.2-1.2
Locomotion velocity, session 80.00.00.0-0.00.0-0.00.0-0.10.0
Locomotion distance, session 80.00.00.1-0.0-0.10.20.1-0.3-0.3
Degree of sensitization distance0.50.50.7-0.6-0.70.8-0.7-0.7-0.7
Degree of sensitization stereotypy1.41.51.8-1.3-1.11.1-1.2-1.4-1.3
Condit. Reinf. active minus inactive responses0.30.30.5-0.6-0.60.7-0.6-0.4-0.6
Condit. Reinf. active-inactive response ratio0.20.20.3-0.5-0.50.6-0.4-0.3-0.5
Condit. Reinf. active responses0.20.20.3-0.4-0.50.6-0.4-0.3-0.4
Condit. Reinf. inactive responses0.00.10.10.30.2-0.10.30.20.2
Incentive salience index mean0.20.20.3-0.5-0.50.5-0.5-0.2-0.4
Condit. Reinf. lever presses0.00.00.1-0.1-0.00.0-0.00.30.1
Time in familiar zone, hab. session 10.20.20.2-0.4-0.40.5-0.4-0.4-0.4
Time in novel zone, hab. session 10.60.50.6-0.7-0.70.7-0.8-0.7-0.8
Total zone transitions, hab. session 10.20.20.4-0.4-0.50.5-0.4-0.6-0.6
Total locomotion distance, hab. session 10.40.60.80.70.8-0.90.90.70.8
Locomotion velocity, hab. session 11.31.82.11.21.3-1.51.41.31.3
Time in familiar zone, hab. session 20.40.40.6-0.8-0.50.5-0.6-0.6-0.6
Time in novel zone, hab. session 20.10.10.20.40.2-0.20.20.10.2
Total zone transitions, hab. session 20.60.81.0-0.8-0.80.9-0.9-1.0-0.9
Total locomotion distance, hab. session 20.50.71.00.70.8-1.00.80.70.9
Locomotion velocity, hab. session 20.40.50.60.60.7-0.80.80.60.7
Novel to familiar place preference ratio0.60.71.0-0.6-0.80.9-0.7-0.8-1.0
Novelty place preference0.60.60.9-0.6-0.80.9-0.6-0.8-1.0
Time in novel zone, NPP test0.80.81.1-0.7-0.91.0-0.7-0.9-1.1
Total zone transitions, NPP test0.20.30.4-0.4-0.50.5-0.5-0.6-0.5
Total locomotion distance, NPP test0.10.20.4-0.3-0.40.4-0.3-0.6-0.4
Locomotion velocity, NPP test0.10.10.3-0.2-0.30.4-0.3-0.5-0.4
Pavlov. Cond. lever latency0.30.40.50.60.6-0.70.70.50.7
Pavlov. Cond. magazine entry latency0.10.10.1-0.4-0.30.3-0.3-0.1-0.3
Pavlov. Cond. change in total contacts0.80.91.10.80.9-1.00.81.11.0
Pavlov. Cond. index score0.20.30.3-0.6-0.50.5-0.6-0.4-0.5
Pavlov. Cond. latency score0.00.00.1-0.3-0.20.2-0.3-0.1-0.2
Pavlov. Cond. lever contacts0.50.60.7-0.8-0.80.8-0.7-0.6-0.8
Pavlov. Cond. magazine entry number0.00.00.10.20.10.00.0-0.00.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.0-0.20.3-0.2-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.7-0.60.7-0.7-0.5-0.6
Pavlov. Cond. response bias1.21.41.6-1.3-1.21.2-1.1-1.1-1.3
Bone: apparent density0.10.10.20.30.3-0.30.50.30.1
Bone surface0.10.10.2-0.3-0.30.4-0.2-0.2-0.4
Bone volume0.00.00.1-0.1-0.20.2-0.0-0.2-0.4
Bone: connectivity density0.20.20.40.40.4-0.40.60.60.4
Bone: cortical apparent density0.00.00.0-0.10.1-0.20.20.10.0
Bone: cortical area1.21.82.1-1.3-1.31.5-1.3-1.3-1.5
Bone: cortical porosity0.10.10.10.20.3-0.30.20.30.4
Bone: cortical porosity0.00.00.0-0.0-0.00.1-0.1-0.00.0
Bone: cortical thickness0.30.50.6-0.6-0.70.8-0.7-0.7-0.8
Bone: cortical thickness1.31.51.9-1.1-1.21.3-1.1-1.4-1.3
Bone: cortical tissue density0.00.00.1-0.00.2-0.30.30.10.1
Bone: elastic displacement1.51.62.11.21.2-1.41.31.31.3
Bone: elastic work0.00.00.0-0.1-0.10.1-0.0-0.1-0.2
Bone: endosteal estimation0.00.10.10.20.2-0.20.30.30.2
Bone: endosteal perimeter0.00.00.1-0.2-0.10.1-0.1-0.1-0.2
Bone: final force0.30.60.8-0.7-0.70.8-0.6-0.7-0.9
Bone: final moment0.50.91.1-1.0-0.91.0-0.8-0.9-1.1
Bone: marrow area0.00.00.10.10.2-0.20.20.20.1
Bone: maximum diameter2.13.94.3-2.0-1.92.1-1.9-1.9-2.0
Bone: maximum force0.20.40.5-0.6-0.60.6-0.5-0.6-0.7
Bone: maximum moment0.30.50.7-0.7-0.70.8-0.6-0.7-0.8
Bone: minimum diameter0.20.30.5-0.4-0.50.6-0.5-0.5-0.7
Bone: periosteal estimation0.20.40.5-0.6-0.60.6-0.5-0.6-0.7
Bone: periosteal perimeter0.20.30.4-0.7-0.50.6-0.5-0.5-0.6
Bone: post-yield work0.50.70.80.70.8-0.80.80.90.8
Bone: stiffness0.81.31.6-1.1-1.11.3-1.1-1.1-1.3
Bone: tissue strength0.50.50.60.60.7-0.70.60.80.7
Bone: trabecular number0.30.40.60.60.6-0.70.80.70.5
Bone: trabecular spacing0.20.20.4-0.3-0.50.5-0.6-0.4-0.3
Bone: trabecular thickness1.11.31.7-1.1-1.11.2-1.0-1.2-1.3
Bone: trabecular tissue density0.91.21.4-1.2-1.01.1-1.0-1.2-1.1
Breakpoint value in progressive ratio session5.66.37.32.42.5-2.72.52.42.6
Distance traveled before self-admin0.20.20.3-0.3-0.50.6-0.5-0.4-0.3
Distance traveled after self-admin0.80.91.30.90.8-0.90.81.11.1
Delta time in closed arm before/after self-admin0.00.00.00.20.0-0.00.1-0.00.1
Delta time in open arm before/after self-admin0.10.10.30.00.3-0.40.40.60.2
Diff in mean of infusions in LGA sessions3.74.15.31.92.0-2.32.11.82.0
Extinction: sum of active levers before priming1.81.82.11.21.3-1.41.41.41.4
Active lever presses in extinction session 60.00.00.1-0.3-0.10.1-0.10.0-0.1
Delta distance traveled before/after self-admin3.43.64.81.51.8-2.01.92.21.8
Delta ambulatory time before/after self-admin1.21.31.71.01.1-1.21.11.31.1
Time in closed arm before self-admin1.61.92.3-1.2-1.31.4-1.3-1.5-1.5
Time in closed arm after self-admin0.00.00.10.2-0.00.0-0.0-0.3-0.0
Time in open arm before self-admin0.90.91.10.90.9-1.00.91.01.1
Time in open arm after self-admin0.70.71.20.50.8-1.00.91.10.8
Sum of active levers in priming session hrs 5-61.51.41.81.21.1-1.21.11.21.3
Time to tail flick, vehicle, before self-admin3.33.34.2-1.8-1.92.0-1.9-1.6-1.8
Time to tail flick, vehicle, after self-admin0.20.20.4-0.1-0.40.6-0.6-0.5-0.2
Time to tail flick, test, before self-admin0.30.30.40.50.5-0.60.60.50.6
Time to tail flick, test, after self-admin0.10.10.1-0.3-0.30.3-0.30.1-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.30.60.3-0.20.20.00.3
Delta time to tail flick, test, before/after SA2.11.82.4-1.2-1.31.5-1.4-1.2-1.4
Ambulatory time before self-admin0.00.00.0-0.0-0.10.1-0.10.00.0
Ambulatory time after self-admin1.21.31.71.11.1-1.11.01.31.3
Total heroin consumption0.50.61.00.60.7-0.80.81.00.8
Area under the delay curve1.81.92.71.21.4-1.61.41.21.4
Delay disc. indifference point, 0s delay1.01.01.40.81.0-1.21.10.91.0
Delay disc. indifference point, 16s delay1.11.11.50.91.1-1.21.11.11.0
Delay disc. indifference point, 2s delay3.33.75.31.61.9-2.31.81.82.0
Delay disc. indifference point, 24s delay0.00.00.10.0-0.20.2-0.2-0.3-0.2
Delay disc. indifference point, 4s delay0.00.00.1-0.2-0.1-0.0-0.1-0.4-0.3
Delay disc. indifference point, 8s delay1.71.82.11.31.3-1.51.31.11.4
Delay discount exponential model param1.31.42.0-1.0-1.21.4-1.2-1.0-1.1
Delay discount hyperbolic model param1.01.11.7-0.9-1.11.3-1.0-0.8-1.0
Fecal boli incidents, locomotor time 10.00.00.0-0.1-0.00.1-0.00.0-0.1
Change in fecal boli incidents, locomotor task0.90.81.00.80.9-1.00.90.90.9
Time >=10cm from walls, locomotor time 10.10.10.10.30.2-0.20.30.30.2
Bouts of movement, locomotor time 12.62.83.41.71.6-1.81.71.51.7
Total resting periods, locomotor time 13.03.34.11.81.8-2.01.91.71.8
Rest time, locomotor task time 10.00.00.10.20.2-0.20.30.20.1
Distance moved, locomotor task time 10.20.20.3-0.5-0.40.4-0.5-0.4-0.4
Vertical activity count, locomotor time 10.10.10.20.10.3-0.30.30.50.3
Time >=10cm from walls, locomotor time 20.10.20.20.30.4-0.40.40.40.5
Bouts of movement, locomotor time 26.36.87.62.72.5-2.82.52.42.7
Total resting periods, locomotor time 25.66.06.72.62.4-2.62.42.22.5
Rest time, locomotor task time 20.00.00.10.30.2-0.20.3-0.00.0
Distance moved, locomotor task time 20.50.60.8-0.9-0.70.8-0.9-0.6-0.7
Vertical activity count, locomotor time 20.20.20.40.10.4-0.50.30.60.5
Weight adjusted by age0.00.00.0-0.10.1-0.20.1-0.1-0.1
Seeking ratio, delayed vs. immediate footshock1.71.92.11.31.4-1.41.41.31.4
Locomotion in novel chamber0.60.81.21.00.7-0.70.61.01.1
Locomotion in novel chamber post-restriction1.61.92.11.31.3-1.31.31.41.5
Progressive ratio0.50.60.80.60.8-0.90.90.60.8
Food seeking constrained by brief footshock6.07.38.12.62.6-2.82.52.72.8
Seeking ratio, punishment vs. effort1.11.31.61.21.1-1.11.01.31.2
Run reversals in cocaine runway, females0.40.30.40.50.6-0.60.60.60.6
Run reversals in cocaine runway, males0.90.81.0-0.8-0.91.0-0.9-0.9-1.0
Latency to leave start box in cocaine runway0.00.00.10.4-0.00.20.10.10.3
Latency to leave start box in cocaine runway, F0.30.30.7-0.2-0.60.8-0.5-0.5-0.3
Latency to leave start box in cocaine runway, M0.00.00.00.20.00.10.1-0.0-0.1
Cd content in liver0.00.00.00.20.1-0.10.00.00.1
Co content in liver2.32.63.21.41.6-1.81.61.71.7
Cu content in liver0.00.10.1-0.0-0.20.3-0.3-0.2-0.3
Fe content in liver1.51.72.1-1.3-1.21.3-1.3-1.4-1.2
K content in liver0.10.10.2-0.4-0.40.4-0.4-0.2-0.3
Mg content in liver0.10.10.2-0.5-0.40.4-0.4-0.3-0.3
Mn content in liver0.91.01.3-1.0-1.01.1-1.0-0.9-1.0
Na content in liver0.10.10.30.50.3-0.30.20.30.4
Rb content in liver0.00.00.10.30.1-0.00.10.00.1
Se content in liver1.72.12.3-1.5-1.41.5-1.5-1.4-1.4
Sr content in liver0.30.20.3-0.5-0.50.5-0.5-0.5-0.5
Zn content in liver0.10.10.1-0.2-0.20.2-0.2-0.2-0.4