Hub : Genes

Pak1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000029784 0.04 0.03 3.4e-03 0.01 0 0 0 6.5e-02 7.9e-02 2.7e-01 1.2e-01
2 BLA gene expression ENSRNOG00000029784 0.09 0.06 5.2e-04 0.06 0.06 0.05 0.05 2.3e-04 6.7e-04 1.1e-03 7.9e-04
3 Brain gene expression ENSRNOG00000029784 0.21 0.11 5.6e-17 0.17 0.18 0.18 0.18 2.3e-15 1.3e-16 2.1e-16 2.9e-16
4 IL gene expression ENSRNOG00000029784 0.52 0.15 1.8e-09 0.27 0.28 0.22 0.24 3.9e-07 2.3e-07 6.5e-06 1.7e-06
5 LHb gene expression ENSRNOG00000029784 0.25 0.15 3.3e-03 0.08 0.03 0.03 0.06 7.0e-03 7.8e-02 8.0e-02 1.7e-02
6 Liver gene expression ENSRNOG00000029784 0.1 0.06 1.4e-09 0.06 0.06 0.06 0.06 4.3e-07 1.6e-07 4.0e-07 3.2e-07
7 Liver intron excision ratio chr1:152151695:152173951 0.04 0.03 3.9e-04 0.02 0.02 0.01 0.01 4.9e-03 3.0e-03 1.0e-02 6.9e-03
8 NAcc gene expression ENSRNOG00000029784 0.12 0.08 2.2e-06 0.08 0.07 0.07 0.08 1.5e-06 3.9e-06 3.2e-06 2.3e-06
9 OFC gene expression ENSRNOG00000029784 0.35 0.15 2.8e-06 0.22 0.22 0.2 0.22 4.7e-06 4.5e-06 1.7e-05 7.5e-06
10 PL gene expression ENSRNOG00000029784 0.86 0.01 4.4e-13 0.16 0.13 0.15 0.15 3.0e-12 7.6e-10 2.9e-11 1.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.72.24.82.1-1.4-1.3-1.60.5-0.50.6-1.7-2.2-1.7
BMI without tail4.59.319.54.2-3.3-2.6-3.20.6-0.71.8-3.5-4.4-3.5
Body weight2.08.617.53.7-2.8-2.8-3.30.4-0.22.0-3.5-4.2-3.5
Epididymis fat weight2.25.210.03.1-2.4-2.0-2.50.5-0.51.1-2.8-3.2-2.8
Glucose0.20.30.9-0.90.4-0.4-0.3-0.80.90.5-0.20.3-0.2
Heart weight0.50.61.7-0.9-0.9-0.7-0.5-1.11.31.0-0.30.1-0.3
Left kidney weight1.74.86.61.4-2.3-2.4-2.5-1.11.32.5-2.5-2.6-2.5
Right kidney weight1.13.14.91.6-2.0-1.8-2.0-0.50.71.8-2.0-2.2-2.0
Tail length4.112.520.63.2-3.8-3.7-4.0-1.01.23.5-4.2-4.5-4.2
Length with tail2.27.914.63.0-2.9-2.8-3.2-0.20.42.4-3.4-3.8-3.4
Length without tail0.10.20.4-0.00.60.50.50.6-0.5-0.60.40.40.4
Liver weight, left0.61.02.01.2-0.8-0.9-1.10.3-0.30.5-1.3-1.4-1.3
Liver weight, right2.43.911.23.3-1.3-1.0-1.61.7-1.70.1-2.1-2.9-2.1
Parametrial fat weight0.71.44.02.0-0.9-0.4-0.71.6-1.3-0.2-0.9-1.6-0.9
Retroperitoneal fat weight4.113.428.65.4-3.8-2.7-3.71.5-1.90.9-4.3-5.2-4.3
Intraocular pressure1.72.48.7-3.00.8-0.30.2-2.42.10.60.71.80.7
Extensor digitorum longus weight0.41.52.60.6-1.2-1.5-1.6-0.50.61.0-1.5-1.4-1.5
Soleus weight1.02.85.11.8-2.0-1.6-1.90.1-0.11.0-2.1-2.3-2.1
Tibialis anterior weight0.20.61.10.8-0.7-0.8-0.80.30.10.7-0.9-1.1-0.9
Tibia length0.30.72.4-1.50.6-0.10.3-1.11.30.70.50.90.5
Number of licking bursts1.11.44.01.60.20.80.41.9-2.0-1.60.2-0.40.2
Food consumed during 24 hour testing period0.80.92.2-1.41.00.10.5-1.51.30.90.51.00.5
Times rat made contact with spout0.40.51.91.4-0.1-0.1-0.40.6-0.7-0.0-0.6-0.9-0.6
Mean time between licks in bursts4.05.610.00.4-2.2-2.7-2.5-2.12.43.2-2.6-2.1-2.6
Mean num. licks in bursts1.11.33.5-1.2-0.2-1.0-0.6-1.81.91.6-0.50.1-0.5
Std. dev. time between licks in bursts2.02.44.11.7-2.0-1.4-1.6-0.20.31.5-1.8-2.0-1.8
Water consumed over 24 hours0.70.92.00.90.91.10.81.1-1.4-1.20.60.20.6
Indifference point 0 sec1.21.94.7-0.7-1.1-1.5-1.1-1.52.12.2-1.0-0.6-1.0
Indifference point AUC0.20.30.5-0.0-0.7-0.6-0.6-0.40.40.5-0.6-0.4-0.6
Indifference point function ln k0.40.61.2-1.01.10.40.7-0.30.50.10.80.90.8
Indifference point function log k0.40.61.2-1.01.10.40.7-0.30.50.10.80.90.8
Delay discounting total patch changes 0 sec1.01.64.0-0.8-1.0-1.4-0.9-1.52.01.9-0.8-0.4-0.8
Delay discounting total patch changes 12 sec1.11.52.30.1-1.2-1.5-1.4-0.81.11.5-1.4-1.1-1.4
Delay discounting total patch changes 18 sec1.52.03.5-0.2-1.5-1.6-1.4-1.51.61.9-1.4-1.0-1.4
Delay discounting total patch changes 24 sec1.01.32.40.1-1.5-1.3-1.2-0.91.01.3-1.2-1.0-1.2
Delay discounting total patch changes 6 sec0.00.00.2-0.3-0.1-0.20.0-0.00.50.4-0.00.1-0.0
Delay discounting time to switch 0 sec1.92.86.81.51.21.81.32.3-2.6-2.30.90.40.9
Delay discounting water rate 0 sec1.21.95.3-1.5-0.8-1.4-0.9-2.02.31.9-0.4-0.0-0.4
Delay discounting water rate 12 sec0.61.03.0-1.3-0.2-0.7-0.3-1.61.71.3-0.00.4-0.0
Delay discounting water rate 18 sec0.60.81.9-0.4-0.8-0.9-0.8-1.41.41.2-0.6-0.2-0.6
Delay discounting water rate 24 sec0.60.92.5-1.60.80.30.6-1.01.10.30.81.30.8
Delay discounting water rate 6 sec0.40.61.9-1.40.50.30.5-0.80.80.20.81.00.8
Locomotor activity0.20.31.01.0-0.7-0.2-0.20.5-0.20.6-0.5-0.9-0.5
Locomotor testing distance1.42.33.80.6-1.9-1.7-1.6-0.71.11.9-1.6-1.7-1.6
Locomotor testing rearing2.33.66.51.9-2.2-1.9-2.0-0.10.31.6-2.3-2.5-2.3
Light reinforcement 10.61.13.31.8-0.20.50.11.7-1.8-1.1-0.1-0.7-0.1
Light reinforcement 20.10.20.60.10.40.40.50.8-0.5-0.40.40.10.4
Reaction time number correct1.01.42.20.01.11.51.51.2-1.0-1.11.40.91.4
Reaction time mean minus median0.60.81.40.1-0.9-1.1-1.0-0.40.81.2-1.0-0.9-1.0
Reaction time mean minus median AUC0.20.30.8-0.3-0.5-0.7-0.4-0.30.70.9-0.5-0.4-0.5
Reaction time num false alarms0.30.41.21.0-0.50.1-0.30.5-1.1-0.8-0.3-0.6-0.3
Reaction time num false alarms AUC0.10.10.50.3-0.10.20.00.2-0.7-0.70.0-0.00.0
Reaction time trials correct on left1.01.42.20.01.11.51.51.2-1.0-1.11.40.91.4
Reaction time trials on left1.01.42.20.01.11.51.51.2-1.0-1.11.40.91.4
Reaction time mean0.20.20.70.9-0.2-0.2-0.30.8-0.4-0.1-0.4-0.6-0.4
Reaction time mean AUC0.10.20.70.60.00.0-0.00.8-0.5-0.4-0.1-0.3-0.1
Median of all reaction times0.20.31.00.70.20.30.21.0-0.7-0.60.1-0.10.1
Reaction time omissions0.30.40.90.4-1.0-0.7-0.70.00.40.5-0.8-0.6-0.8
Reaction time false alarm rate0.10.20.40.2-0.4-0.4-0.6-0.3-0.2-0.2-0.5-0.4-0.5
Reaction time premature initiation rate3.34.47.22.0-2.4-2.2-2.4-0.20.72.0-2.5-2.7-2.5
Reaction time premature initiations1.31.93.41.6-1.7-1.2-1.40.30.31.3-1.5-1.8-1.5
Std. dev. reaction times1.01.42.10.7-1.2-1.4-1.4-0.20.61.2-1.4-1.4-1.4
Reaction time trials completed1.01.42.20.01.11.51.51.2-1.0-1.11.40.91.4
Reaction time trials AUC0.71.01.60.20.91.21.31.2-0.9-0.91.10.71.1
Social response proportion0.80.92.91.60.20.50.21.7-1.5-0.7-0.2-0.8-0.2
Social responses1.11.44.52.1-0.9-0.4-0.81.2-1.1-0.0-1.1-1.6-1.1
Social time1.21.64.41.30.41.30.92.1-2.0-1.70.60.00.6
Conditioned locomotion0.30.30.5-0.40.50.60.70.3-0.2-0.50.70.70.7
Cocaine response after cond. corrected0.10.10.4-0.0-0.6-0.4-0.5-0.10.1-0.0-0.4-0.2-0.4
Cocaine response after cond. not corrected0.00.00.2-0.40.0-0.00.00.10.1-0.20.10.30.1
Cocaine response before conditioning0.80.91.8-0.31.31.11.30.8-0.5-0.61.10.81.1
Saline control response1.11.42.70.2-1.2-1.4-1.2-0.91.21.6-1.2-1.1-1.2
Condit. Reinf. active minus inactive responses4.45.59.8-0.9-2.1-2.9-2.4-2.42.93.1-2.1-1.5-2.1
Condit. Reinf. active-inactive response ratio1.61.73.3-1.1-1.1-1.5-1.2-1.71.81.5-1.0-0.4-1.0
Condit. Reinf. active responses6.28.615.7-0.6-2.8-3.6-3.0-2.83.54.0-2.8-2.1-2.8
Condit. Reinf. inactive responses3.13.87.30.8-2.0-2.2-2.0-1.21.82.7-2.1-2.0-2.1
Condit. Reinf. lever presses6.08.222.4-2.7-1.6-3.0-2.0-3.84.74.2-1.5-0.4-1.5
Condit. Reinf. lever reinforcers received6.28.716.4-0.9-2.7-3.6-3.0-3.03.74.0-2.7-1.9-2.7
Pavlov. Cond. lever latency6.59.025.93.41.63.01.84.1-5.1-4.21.3-0.11.3
Pavlov. Cond. magazine entry latency2.12.47.9-2.8-0.2-0.9-0.2-2.22.61.50.31.10.3
Pavlov. Cond. change in total contacts4.25.816.7-2.5-1.3-2.5-1.6-3.24.13.4-1.1-0.1-1.1
Pavlov. Cond. index score5.36.920.2-3.3-1.3-2.5-1.5-3.74.53.5-0.90.3-0.9
Pavlov. Cond. latency score4.75.917.7-3.3-1.0-2.2-1.2-3.54.23.2-0.70.5-0.7
Pavlov. Cond. lever contacts6.38.724.8-3.1-1.7-3.0-1.9-4.05.04.2-1.4-0.1-1.4
Pavlov. Cond. magazine entry number4.75.816.43.80.71.91.03.8-4.1-2.60.3-1.10.3
Pavlov. Cond. intertrial magazine entries2.02.56.42.5-1.7-1.0-1.40.6-0.60.9-1.8-2.3-1.8
Pavlov. Cond. lever-magazine prob. diff.5.16.719.2-3.1-1.3-2.5-1.5-3.64.43.5-1.00.2-1.0
Pavlov. Cond. response bias6.89.427.0-3.5-1.7-3.0-1.9-4.35.24.3-1.30.1-1.3
Conditioned reinforcement - actives1.21.24.2-2.00.8-0.10.4-1.41.50.60.61.20.6
Conditioned reinforcement - inactives0.10.10.1-0.00.30.40.30.3-0.2-0.30.20.30.2
Conditioned locomotion1.11.34.6-2.20.90.10.6-1.31.40.50.81.40.8
Intermittent access intake day 1-15 change0.90.92.8-1.70.60.00.4-1.21.40.60.51.10.5
Intermittent access intake escalation1.01.03.1-1.80.4-0.20.2-1.41.60.90.41.00.4
Intermittent access intake escalation 20.20.20.6-0.5-0.2-0.3-0.2-0.70.80.7-0.30.0-0.3
Intermitt. access day 1 inactive lever presses0.20.20.70.7-0.10.50.30.8-0.8-0.60.0-0.10.0
Intermitt. access day 15 inactive lever presses0.10.10.1-0.00.20.30.30.2-0.1-0.20.20.40.2
Intermitt. access escalation Index0.20.20.40.20.50.40.40.6-0.4-0.40.40.20.4
Intermittent access day 1 total infusions0.60.71.7-0.8-0.4-0.9-0.7-1.31.31.1-0.6-0.1-0.6
Intermittent access day 15 total infusions1.31.54.4-2.10.3-0.5-0.0-1.92.01.10.11.00.1
Intermittent access terminal intake (last 3 days)0.80.82.5-1.3-0.0-0.7-0.4-1.51.61.1-0.30.4-0.3
Intermittent access total infusions0.60.61.8-1.0-0.1-0.7-0.5-1.31.31.0-0.40.2-0.4
Intermittent access day 1 locomotion0.30.30.9-0.90.70.30.4-0.40.3-0.20.50.70.5
Intermittent access day 15 total locomotion0.70.72.1-1.2-0.1-0.6-0.3-1.31.41.1-0.20.3-0.2
Intermittent access total locomotion0.40.41.1-0.7-0.1-0.7-0.5-1.01.00.9-0.4-0.0-0.4
Intermittent access standard deviation0.10.10.20.2-0.3-0.3-0.4-0.20.30.4-0.3-0.3-0.3
Cocaine induced anxiety0.70.82.50.80.60.90.61.4-1.6-1.30.30.00.3
Post-drug Anxiety0.10.10.20.30.00.30.20.5-0.5-0.4-0.00.0-0.0
Baseline Anxiety1.01.13.4-1.3-0.4-0.8-0.5-1.61.81.4-0.30.3-0.3
Lifetime Intake0.60.72.1-1.1-0.1-0.7-0.4-1.31.41.0-0.30.3-0.3
Incentive Sensitization - Responses2.82.85.1-0.4-1.5-1.9-1.7-2.02.22.3-1.5-0.9-1.5
Incentive Sensitization - Breakpoint2.52.54.7-0.4-1.4-1.8-1.6-1.92.22.2-1.4-0.8-1.4
Progressive ratio test 1 active lever presses0.20.20.4-0.10.60.50.50.3-0.3-0.50.40.40.4
Progressive ratio test 1 breakpoint0.20.20.4-0.10.70.50.50.4-0.4-0.60.50.40.5
Progressive ratio test 1 inactive lever presses0.00.00.0-0.0-0.2-0.1-0.1-0.10.20.2-0.0-0.0-0.0
Progressive ratio test 2 active lever presses1.82.03.9-0.6-1.1-1.6-1.4-1.92.01.9-1.2-0.5-1.2
Progressive ratio test 2 breakpoint1.51.62.9-0.3-1.0-1.5-1.3-1.61.71.7-1.2-0.6-1.2
Progressive ratio test 2 inactive lever presses0.60.71.6-0.5-0.5-0.9-0.7-1.01.31.1-0.6-0.2-0.6
Total sessions with >9 infusions0.30.31.2-0.90.3-0.20.1-0.71.10.70.10.60.1
Short access day 1 total inactive lever presses0.10.10.3-0.5-0.1-0.2-0.1-0.50.60.2-0.10.3-0.1
Short access day 10 total inactive lever presses0.50.51.51.20.00.70.41.2-1.1-0.60.1-0.20.1
Short access day 1 total infusions0.70.72.1-0.6-0.3-0.9-0.6-1.01.41.3-0.5-0.1-0.5
Short access day 10 total infusions0.70.71.6-0.8-0.4-1.0-0.8-1.31.31.0-0.6-0.1-0.6
Short access total infusions0.30.30.8-0.5-0.2-0.6-0.4-0.70.90.8-0.4-0.0-0.4
Short access day 1 locomotion1.11.23.8-2.00.90.30.8-1.01.30.30.81.50.8
Short access day 10 total locomotion0.10.10.2-0.3-0.1-0.4-0.3-0.50.50.5-0.4-0.2-0.4
Short access total locomotion0.10.10.3-0.20.50.40.40.3-0.2-0.20.30.30.3
Compulsive drug intake0.00.00.10.20.10.10.10.3-0.1-0.00.1-0.00.1
One hour access (0.3 mA shock)1.71.93.8-0.7-1.1-1.5-1.3-1.81.91.8-1.3-0.5-1.3
One hour access (shock baseline)0.80.92.2-0.9-0.5-0.9-0.6-1.41.51.3-0.7-0.0-0.7
Number of responses in last shaping day1.21.22.21.4-1.5-0.9-1.20.1-0.00.7-1.3-1.4-1.3
Context. condit. distance diff. score1.21.55.2-2.30.6-0.6-0.1-1.91.90.80.31.10.3
Locomotion velocity, session 10.91.02.0-1.31.00.81.0-0.40.3-0.51.21.41.2
Locomotion distance, session 10.20.20.9-0.90.10.10.4-0.20.60.20.50.70.5
Locomotion velocity, session 20.30.31.1-0.7-0.2-0.4-0.3-1.00.90.7-0.20.2-0.2
Locomotion distance, session 20.00.00.10.1-0.2-0.1-0.10.10.20.3-0.1-0.2-0.1
Locomotion velocity, session 30.10.10.4-0.70.1-0.10.1-0.70.60.30.20.40.2
Locomotion distance, session 31.01.03.6-1.90.5-0.00.4-1.51.30.40.71.20.7
Stereotopy head waving bouts, day 31.11.34.52.10.00.60.21.8-1.7-0.7-0.2-0.9-0.2
Stereotopy head waving duration, day 30.10.20.30.30.40.50.50.6-0.4-0.20.40.10.4
Locomotion velocity, session 70.20.20.7-0.80.5-0.00.1-0.60.3-0.20.20.50.2
Locomotion distance, session 70.50.61.6-0.9-0.4-0.9-0.8-1.31.00.6-0.6-0.1-0.6
Stereotopy head waving bouts, day 70.30.30.8-0.40.90.50.7-0.10.20.10.70.60.7
Stereotopy head waving duration, day 70.20.20.6-0.50.3-0.10.1-0.60.80.80.10.20.1
Locomotion velocity, session 82.73.211.9-3.41.2-0.60.1-2.72.50.90.61.80.6
Locomotion distance, session 80.60.92.7-1.60.4-0.6-0.1-1.41.60.90.10.70.1
Degree of sensitization distance1.71.73.11.3-1.5-1.3-1.50.2-0.10.8-1.7-1.8-1.7
Degree of sensitization stereotypy1.11.23.1-1.81.00.20.6-1.31.40.70.81.20.8
Condit. Reinf. active minus inactive responses1.41.62.91.0-1.7-1.3-1.4-0.20.20.9-1.5-1.5-1.5
Condit. Reinf. active-inactive response ratio1.31.42.51.0-1.6-1.2-1.3-0.00.31.0-1.5-1.5-1.5
Condit. Reinf. active responses0.70.81.51.0-1.2-0.8-1.00.1-0.20.4-1.1-1.2-1.1
Condit. Reinf. inactive responses0.00.00.00.1-0.00.1-0.0-0.0-0.2-0.1-0.0-0.1-0.0
Incentive salience index mean1.01.22.10.5-1.5-1.3-1.3-0.70.61.0-1.3-1.2-1.3
Condit. Reinf. lever presses0.30.41.4-0.7-0.3-0.5-0.5-1.20.80.5-0.30.1-0.3
Time in familiar zone, hab. session 10.00.00.1-0.20.1-0.0-0.1-0.30.10.0-0.00.1-0.0
Time in novel zone, hab. session 10.30.30.70.9-0.7-0.4-0.50.5-0.30.1-0.6-0.8-0.6
Total zone transitions, hab. session 10.91.32.0-0.41.41.21.41.0-0.8-1.11.31.01.3
Total locomotion distance, hab. session 12.43.412.03.5-1.10.0-0.62.6-2.4-0.7-1.1-2.2-1.1
Locomotion velocity, hab. session 12.02.910.23.2-1.00.1-0.42.5-2.3-0.7-0.9-2.0-0.9
Time in familiar zone, hab. session 20.70.81.5-0.3-0.7-0.9-0.9-1.21.11.2-0.8-0.5-0.8
Time in novel zone, hab. session 20.00.00.1-0.20.00.00.10.20.0-0.20.20.20.2
Total zone transitions, hab. session 20.40.50.8-0.60.70.60.90.5-0.1-0.30.90.70.9
Total locomotion distance, hab. session 21.82.57.52.7-1.5-0.5-0.91.9-1.5-0.1-1.3-2.1-1.3
Locomotion velocity, hab. session 22.02.88.52.9-1.6-0.5-1.02.0-1.6-0.1-1.4-2.3-1.4
Novel to familiar place preference ratio0.10.10.30.10.50.10.20.6-0.1-0.10.1-0.00.1
Novelty place preference0.00.00.10.10.4-0.10.00.30.10.1-0.0-0.0-0.0
Time in novel zone, NPP test0.00.00.1-0.20.3-0.2-0.00.00.30.2-0.00.0-0.0
Total zone transitions, NPP test0.50.71.6-1.20.80.60.90.00.2-0.51.11.21.1
Total locomotion distance, NPP test1.31.85.22.3-1.4-0.4-0.81.6-1.4-0.3-1.1-1.8-1.1
Locomotion velocity, NPP test1.52.26.82.6-1.4-0.2-0.72.0-1.7-0.5-1.0-1.8-1.0
Pavlov. Cond. lever latency0.50.71.70.70.40.80.71.3-1.2-1.10.60.10.6
Pavlov. Cond. magazine entry latency1.31.73.1-0.5-1.0-1.7-1.3-1.31.61.8-1.3-0.9-1.3
Pavlov. Cond. change in total contacts0.91.02.0-0.8-0.6-1.1-0.9-1.41.41.2-0.8-0.3-0.8
Pavlov. Cond. index score1.72.23.9-0.6-1.2-1.7-1.5-1.81.92.0-1.4-0.9-1.4
Pavlov. Cond. latency score1.51.93.5-0.6-1.0-1.6-1.4-1.71.81.9-1.3-0.8-1.3
Pavlov. Cond. lever contacts0.91.12.1-0.5-0.8-1.1-1.1-1.41.31.3-1.0-0.5-1.0
Pavlov. Cond. magazine entry number1.51.93.60.71.01.61.31.6-1.9-1.91.20.71.2
Pavlov. Cond. intertrial magazine entries0.40.51.51.0-0.10.70.31.0-1.2-0.90.1-0.20.1
Pavlov. Cond. lever-magazine prob. diff.1.31.73.0-0.6-0.9-1.5-1.3-1.61.71.7-1.2-0.7-1.2
Pavlov. Cond. response bias0.70.91.4-0.2-0.9-1.1-1.0-1.01.01.2-1.0-0.7-1.0
Bone: apparent density0.20.30.6-0.40.80.50.50.1-0.3-0.60.50.60.5
Bone surface0.71.23.1-1.4-0.3-1.1-0.8-1.71.81.3-0.50.1-0.5
Bone volume0.60.92.3-0.9-0.4-1.1-0.9-1.51.41.2-0.7-0.2-0.7
Bone: connectivity density0.60.92.1-1.41.10.70.9-0.40.3-0.51.11.31.1
Bone: cortical apparent density0.10.10.50.6-0.10.2-0.00.4-0.7-0.5-0.1-0.3-0.1
Bone: cortical area1.01.62.8-0.1-1.0-1.7-1.5-1.01.11.3-1.4-1.1-1.4
Bone: cortical porosity0.30.30.5-0.20.70.60.70.4-0.0-0.10.70.50.7
Bone: cortical porosity0.30.30.6-0.10.70.70.80.5-0.2-0.20.70.50.7
Bone: cortical thickness0.10.10.20.2-0.1-0.3-0.30.3-0.3-0.2-0.4-0.4-0.4
Bone: cortical thickness0.40.41.3-1.1-0.4-0.7-0.4-0.81.00.5-0.10.2-0.1
Bone: cortical tissue density0.10.20.50.6-0.00.30.10.5-0.7-0.50.0-0.20.0
Bone: elastic displacement0.60.71.5-0.10.70.90.80.7-0.8-1.20.90.70.9
Bone: elastic work1.72.33.2-1.01.61.61.60.8-0.9-1.81.71.71.7
Bone: endosteal estimation1.53.24.8-0.1-1.7-2.1-2.0-1.91.82.2-1.9-1.4-1.9
Bone: endosteal perimeter1.93.97.1-0.9-1.4-2.3-1.9-2.72.62.6-1.8-1.0-1.8
Bone: final force0.10.21.1-1.10.6-0.20.1-0.30.4-0.00.20.40.2
Bone: final moment0.10.21.0-1.00.5-0.3-0.1-0.40.50.20.00.30.0
Bone: marrow area1.32.84.1-0.0-1.6-2.0-1.9-1.71.62.0-1.8-1.4-1.8
Bone: maximum diameter1.63.05.1-0.8-1.1-2.2-1.8-2.02.22.3-1.6-1.0-1.6
Bone: maximum force0.30.52.6-1.60.8-0.20.2-0.70.80.10.40.70.4
Bone: maximum moment0.30.52.4-1.60.7-0.30.0-0.80.90.30.20.60.2
Bone: minimum diameter1.73.24.60.7-1.9-2.1-2.2-1.11.01.8-2.2-2.0-2.2
Bone: periosteal estimation1.93.96.2-0.5-1.6-2.5-2.2-2.12.22.3-2.0-1.4-2.0
Bone: periosteal perimeter1.52.54.2-0.3-1.2-1.9-1.6-1.91.82.0-1.6-1.0-1.6
Bone: post-yield work0.10.20.5-0.60.70.30.50.10.1-0.10.50.50.5
Bone: stiffness0.10.10.4-0.60.70.10.20.2-0.1-0.40.30.30.3
Bone: tissue strength2.92.95.3-0.52.31.91.91.5-1.3-1.81.81.51.8
Bone: trabecular number0.71.22.0-0.61.41.21.10.6-0.9-1.41.11.11.1
Bone: trabecular spacing0.20.20.7-0.3-0.6-0.4-0.2-0.60.90.8-0.1-0.0-0.1
Bone: trabecular thickness0.20.30.60.3-0.5-0.6-0.7-0.20.10.3-0.7-0.6-0.7
Bone: trabecular tissue density1.01.44.52.1-0.8-0.3-0.71.4-1.3-0.2-0.9-1.6-0.9
Breakpoint value in progressive ratio session0.20.20.5-0.60.50.40.4-0.1-0.0-0.50.60.70.6
Distance traveled before self-admin0.10.10.20.4-0.20.20.10.4-0.4-0.3-0.0-0.0-0.0
Distance traveled after self-admin1.31.52.30.50.91.51.31.5-1.5-1.51.10.71.1
Delta time in closed arm before/after self-admin1.01.01.80.2-1.4-1.2-1.3-0.70.50.7-1.2-1.0-1.2
Delta time in open arm before/after self-admin1.00.92.0-0.2-0.6-1.1-0.9-1.21.41.4-0.8-0.5-0.8
Diff in mean of infusions in LGA sessions1.11.23.51.40.50.80.51.6-1.9-1.50.3-0.20.3
Extinction: sum of active levers before priming0.40.40.60.0-0.7-0.7-0.8-0.70.50.6-0.7-0.5-0.7
Active lever presses in extinction session 60.40.40.6-0.80.20.50.8-0.20.60.30.80.80.8
Delta distance traveled before/after self-admin0.50.50.80.30.60.90.90.8-0.7-0.60.80.40.8
Delta ambulatory time before/after self-admin1.01.01.7-0.31.01.21.30.8-0.7-0.91.31.01.3
Time in closed arm before self-admin1.01.11.8-1.11.31.01.30.20.1-0.41.41.31.4
Time in closed arm after self-admin1.71.83.3-1.81.51.11.4-0.1-0.0-1.01.61.81.6
Time in open arm before self-admin0.60.62.01.1-0.30.50.11.0-1.4-1.1-0.1-0.4-0.1
Time in open arm after self-admin1.01.12.11.1-1.0-1.1-1.2-0.10.10.9-1.3-1.5-1.3
Sum of active levers in priming session hrs 5-60.10.10.60.8-0.30.0-0.10.4-0.30.0-0.1-0.5-0.1
Time to tail flick, vehicle, before self-admin0.30.31.31.2-0.20.1-0.20.5-0.7-0.4-0.2-0.5-0.2
Time to tail flick, vehicle, after self-admin0.70.72.3-1.50.2-0.10.2-1.31.20.60.50.80.5
Time to tail flick, test, before self-admin0.40.41.0-0.7-0.2-0.8-0.6-1.00.80.5-0.4-0.1-0.4
Time to tail flick, test, after self-admin1.21.21.7-0.4-1.3-1.3-1.2-1.31.21.2-0.9-0.7-0.9
Delta time to tail flick, vehicle, before/after SA1.41.45.1-2.30.70.20.7-1.31.50.50.91.50.9
Delta time to tail flick, test, before/after SA0.10.10.20.3-0.10.40.30.5-0.4-0.20.30.00.3
Ambulatory time before self-admin0.10.10.3-0.30.30.40.40.1-0.2-0.50.40.60.4
Ambulatory time after self-admin1.71.92.8-0.21.31.71.61.2-1.2-1.61.61.31.6
Total heroin consumption0.00.00.1-0.20.00.10.2-0.10.1-0.10.30.30.3
Area under the delay curve0.30.31.3-1.1-0.1-0.10.1-0.90.80.20.20.70.2
Delay disc. indifference point, 0s delay0.50.51.0-0.1-0.8-0.8-0.7-0.80.91.0-0.6-0.5-0.6
Delay disc. indifference point, 16s delay0.60.61.5-1.20.60.60.8-0.40.3-0.40.81.20.8
Delay disc. indifference point, 2s delay0.40.51.3-0.8-0.3-0.5-0.3-1.01.10.9-0.20.1-0.2
Delay disc. indifference point, 24s delay0.20.20.5-0.50.40.40.40.0-0.3-0.70.50.60.5
Delay disc. indifference point, 4s delay1.31.32.4-0.6-1.1-1.3-1.1-1.51.51.5-1.0-0.5-1.0
Delay disc. indifference point, 8s delay0.40.41.8-1.30.1-0.10.2-0.90.90.20.30.80.3
Delay discount exponential model param0.30.31.31.1-0.0-0.0-0.20.8-0.7-0.1-0.3-0.7-0.3
Delay discount hyperbolic model param0.40.41.21.10.20.30.11.0-1.0-0.5-0.0-0.5-0.0
Fecal boli incidents, locomotor time 11.01.13.8-1.9-0.3-0.20.1-1.61.50.70.51.00.5
Change in fecal boli incidents, locomotor task1.21.12.51.01.01.00.81.6-1.6-1.30.60.10.6
Time >=10cm from walls, locomotor time 10.70.72.3-1.50.60.20.6-0.70.90.30.81.00.8
Bouts of movement, locomotor time 10.20.20.7-0.8-0.2-0.4-0.2-0.70.80.5-0.20.2-0.2
Total resting periods, locomotor time 10.30.31.2-1.10.40.20.3-0.50.5-0.00.30.70.3
Rest time, locomotor task time 10.60.61.7-1.30.80.50.7-0.30.3-0.40.81.10.8
Distance moved, locomotor task time 11.71.83.00.9-1.4-1.5-1.6-0.60.61.3-1.7-1.6-1.7
Vertical activity count, locomotor time 11.01.01.80.7-1.3-1.1-1.1-0.50.61.0-1.2-1.1-1.2
Time >=10cm from walls, locomotor time 20.70.71.5-0.7-0.7-0.9-0.7-1.21.21.1-0.5-0.3-0.5
Bouts of movement, locomotor time 20.30.30.70.2-0.5-0.6-0.5-0.30.60.9-0.6-0.6-0.6
Total resting periods, locomotor time 20.10.10.30.1-0.3-0.4-0.3-0.20.40.6-0.4-0.3-0.4
Rest time, locomotor task time 21.41.63.00.51.21.41.21.5-1.7-1.71.10.61.1
Distance moved, locomotor task time 23.13.66.0-0.3-1.6-2.2-2.0-2.02.12.4-2.0-1.3-2.0
Vertical activity count, locomotor time 22.72.93.90.2-1.8-1.9-1.9-1.51.52.0-2.0-1.4-2.0
Weight adjusted by age2.02.33.30.7-1.6-1.8-1.8-1.11.01.6-1.7-1.6-1.7
Seeking ratio, delayed vs. immediate footshock0.10.20.60.10.30.40.30.3-0.5-0.80.20.40.2
Locomotion in novel chamber0.81.03.7-1.91.40.20.7-0.50.80.10.81.10.8
Locomotion in novel chamber post-restriction1.82.28.1-2.81.20.10.7-1.61.90.61.01.81.0
Progressive ratio0.60.72.8-1.70.70.20.6-0.70.7-0.20.81.20.8
Food seeking constrained by brief footshock1.11.42.50.5-1.1-1.3-1.2-0.50.91.6-1.3-1.3-1.3
Seeking ratio, punishment vs. effort2.02.44.82.2-1.6-1.2-1.50.30.01.4-1.8-2.2-1.8
Run reversals in cocaine runway, females3.53.55.51.4-2.3-2.0-2.3-0.60.51.4-2.3-2.3-2.3
Run reversals in cocaine runway, males0.80.72.6-1.60.40.20.4-1.10.9-0.00.71.20.7
Latency to leave start box in cocaine runway0.80.82.41.40.10.80.41.4-1.5-1.10.2-0.30.2
Latency to leave start box in cocaine runway, F0.50.62.11.4-0.70.1-0.30.9-1.0-0.4-0.5-0.8-0.5
Latency to leave start box in cocaine runway, M1.41.42.00.31.31.41.31.2-1.2-1.31.20.81.2
Cd content in liver0.30.30.70.8-0.5-0.3-0.50.5-0.6-0.3-0.5-0.7-0.5
Co content in liver1.61.92.9-0.2-1.4-1.6-1.5-1.71.51.6-1.4-0.9-1.4
Cu content in liver1.92.33.90.8-2.0-1.6-1.7-0.91.01.6-1.7-1.6-1.7
Fe content in liver0.20.30.6-0.5-0.3-0.6-0.5-0.80.80.5-0.4-0.0-0.4
K content in liver0.30.31.01.00.00.40.20.8-0.9-0.4-0.0-0.4-0.0
Mg content in liver0.00.00.10.1-0.2-0.2-0.2-0.20.20.3-0.2-0.2-0.2
Mn content in liver1.61.92.8-0.21.51.61.51.1-1.3-1.71.51.21.5
Na content in liver0.60.71.2-0.10.91.11.10.7-0.4-0.51.00.81.0
Rb content in liver0.70.91.4-0.2-0.8-1.2-1.1-1.11.11.2-1.0-0.6-1.0
Se content in liver1.92.34.60.81.01.81.41.9-2.2-2.11.20.71.2
Sr content in liver0.30.31.0-1.00.40.10.2-0.70.60.00.40.70.4
Zn content in liver1.81.94.2-0.3-1.4-1.6-1.3-1.41.82.0-1.2-0.9-1.2