Ror1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000029449	0.11	0.08	6.1e-03	0.02	0.04	0.03	0.03	2.3e-02	5.4e-03	9.4e-03	7.0e-03
2	Brain	gene expression	ENSRNOG00000029449	0.06	0.05	6.5e-05	0.05	0.04	0.04	0.05	2.5e-05	6.4e-05	1.4e-04	1.9e-05
3	LHb	gene expression	ENSRNOG00000029449	0.14	0.1	2.5e-03	0.11	0.11	0.1	0.1	1.7e-03	1.4e-03	2.3e-03	2.6e-03
4	Liver	isoform ratio	ENSRNOT00000045987	0.09	0.05	2.7e-07	0.03	0.04	0.04	0.04	1.4e-04	9.2e-06	3.1e-05	8.3e-06
5	Liver	isoform ratio	ENSRNOT00000097167	0.15	0.09	2.8e-09	0.02	0.06	0.06	0.06	4.7e-03	1.3e-07	9.3e-08	2.5e-07
6	NAcc	gene expression	ENSRNOG00000029449	0.2	0.16	2.9e-08	0.09	0.1	0.07	0.1	1.8e-07	5.3e-08	3.0e-06	1.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
BMI with tail	0.2	0.7	1.1	-0.6	1.1	1.0	0.3	-0.8	0.8
BMI without tail	0.3	0.6	1.5	0.9	1.2	0.7	-0.4	0.3	0.9
Body weight	0.2	0.7	1.5	-1.1	-0.3	0.0	1.0	-1.2	-0.3
Epididymis fat weight	1.2	2.9	4.1	-0.8	-1.4	-2.0	2.0	-1.9	-1.7
Glucose	0.2	0.2	0.5	-0.7	0.4	0.5	0.4	-0.4	0.4
Heart weight	2.6	3.7	5.7	-2.2	-1.9	-2.0	1.8	-1.0	-2.4
Left kidney weight	0.9	2.7	5.6	-2.4	-0.9	-0.7	1.9	-1.9	-1.4
Right kidney weight	1.2	3.5	7.6	-2.8	-1.4	-0.9	1.8	-1.9	-1.9
Tail length	0.4	1.2	2.7	0.3	-1.4	-1.6	0.6	-0.1	-1.4
Length with tail	0.4	1.5	2.6	-0.9	-1.6	-1.3	1.1	-0.8	-1.4
Length without tail	0.5	1.1	2.7	-1.6	-0.8	0.1	1.0	-1.4	-0.6
Liver weight, left	1.8	2.9	4.1	-1.2	-2.0	-1.6	1.6	-1.7	-1.9
Liver weight, right	6.3	10.4	13.4	-3.1	-2.9	-2.8	3.7	-3.5	-3.3
Parametrial fat weight	1.4	2.8	7.4	0.0	2.1	2.7	-1.3	0.0	1.9
Retroperitoneal fat weight	0.2	0.6	1.4	-0.3	-0.5	-0.8	0.9	-1.2	-0.6
Intraocular pressure	0.0	0.1	0.2	0.3	-0.2	-0.1	0.0	-0.4	-0.0
Extensor digitorum longus weight	1.0	3.9	7.1	-2.5	-1.2	-1.1	2.7	-2.2	-1.6
Soleus weight	0.1	0.2	0.5	0.5	-0.5	-0.7	0.0	0.2	-0.4
Tibialis anterior weight	5.0	17.2	29.5	1.8	4.8	5.4	-4.0	2.9	4.8
Tibia length	2.1	6.0	9.1	-1.8	-3.0	-2.6	2.5	-1.8	-2.8
Number of licking bursts	0.1	0.1	0.2	0.4	0.4	0.1	0.0	-0.3	0.4
Food consumed during 24 hour testing period	0.4	0.5	0.8	0.9	-0.6	-0.9	-0.5	0.6	-0.6
Times rat made contact with spout	0.2	0.2	0.6	0.0	0.8	0.5	-0.2	0.3	0.5
Mean time between licks in bursts	5.0	7.0	10.4	-2.3	-3.2	-2.8	2.4	-1.7	-3.2
Mean num. licks in bursts	0.1	0.1	0.3	-0.3	0.3	0.3	-0.3	0.6	0.0
Std. dev. time between licks in bursts	0.7	0.8	3.1	-1.8	-0.5	0.1	0.5	-0.7	-0.8
Water consumed over 24 hours	0.3	0.4	0.8	-0.9	0.6	0.7	0.2	-0.9	0.1
Indifference point 0 sec	4.6	7.4	14.4	0.7	3.4	3.8	-2.3	1.5	3.2
Indifference point AUC	1.6	1.9	2.8	1.3	1.4	1.1	-1.7	1.4	1.3
Indifference point function ln k	1.0	1.4	1.8	-1.2	-1.2	-0.9	1.4	-1.2	-1.2
Indifference point function log k	1.0	1.4	1.8	-1.2	-1.2	-0.9	1.4	-1.2	-1.2
Delay discounting total patch changes 0 sec	4.3	6.9	13.6	0.6	3.4	3.7	-2.2	1.4	3.1
Delay discounting total patch changes 12 sec	1.4	1.8	3.5	0.6	1.9	1.7	-1.1	0.6	1.6
Delay discounting total patch changes 18 sec	2.4	3.2	6.4	0.4	2.3	2.5	-1.3	0.8	2.2
Delay discounting total patch changes 24 sec	1.1	1.3	3.3	-0.4	1.5	1.8	-0.7	0.2	1.3
Delay discounting total patch changes 6 sec	4.0	6.1	11.4	1.2	3.4	2.7	-2.0	2.2	2.8
Delay discounting time to switch 0 sec	0.6	1.0	2.9	0.6	-0.8	-1.7	1.0	-0.5	-0.8
Delay discounting water rate 0 sec	0.8	1.3	2.8	0.2	1.2	1.7	-1.1	0.7	1.3
Delay discounting water rate 12 sec	1.5	2.3	5.8	-0.2	2.0	2.4	-1.2	0.3	1.6
Delay discounting water rate 18 sec	0.3	0.4	0.9	-0.5	1.0	0.9	-0.0	0.1	0.6
Delay discounting water rate 24 sec	0.3	0.5	1.7	-1.3	0.0	0.5	0.6	-0.7	-0.1
Delay discounting water rate 6 sec	0.1	0.2	0.7	-0.8	-0.3	0.3	-0.1	0.1	-0.3
Locomotor activity	0.1	0.1	0.2	-0.4	0.2	0.5	0.2	-0.1	0.3
Locomotor testing distance	1.1	1.8	3.5	0.4	1.5	1.9	-1.2	1.0	1.5
Locomotor testing rearing	0.1	0.1	0.3	0.1	0.4	0.4	0.1	0.0	0.5
Light reinforcement 1	0.2	0.4	0.9	-1.0	-0.3	-0.4	0.6	-0.8	-0.7
Light reinforcement 2	0.5	0.7	1.3	-0.7	-0.7	-0.7	0.9	-1.1	-0.8
Reaction time number correct	0.3	0.5	1.7	1.3	-0.1	-0.2	-0.9	0.7	0.1
Reaction time mean minus median	1.4	1.9	2.5	1.6	1.4	1.0	-1.1	1.3	1.6
Reaction time mean minus median AUC	0.5	0.7	1.5	1.2	0.6	0.4	-0.7	0.9	0.9
Reaction time num false alarms	0.5	0.7	1.3	0.7	0.5	0.5	-1.2	1.2	0.5
Reaction time num false alarms AUC	1.2	1.7	3.0	1.1	1.1	1.0	-1.7	1.7	1.0
Reaction time trials correct on left	0.3	0.5	1.7	1.3	-0.1	-0.2	-0.9	0.7	0.1
Reaction time trials on left	0.4	0.5	1.8	1.3	-0.0	-0.1	-0.9	0.7	0.2
Reaction time mean	0.7	0.9	1.8	1.0	1.3	1.0	-0.4	0.3	1.3
Reaction time mean AUC	0.3	0.5	1.0	0.6	0.9	0.6	0.1	-0.3	1.0
Median of all reaction times	0.4	0.6	1.2	0.8	1.0	0.7	-0.3	0.1	1.1
Reaction time omissions	0.7	1.0	2.3	0.8	1.5	1.0	-0.5	0.5	1.3
Reaction time false alarm rate	0.9	1.3	1.9	0.5	1.2	1.2	-1.3	1.4	1.1
Reaction time premature initiation rate	0.2	0.3	1.0	-1.0	-0.1	-0.4	0.2	-0.0	-0.7
Reaction time premature initiations	0.2	0.2	0.7	-0.4	-0.4	-0.6	0.0	-0.1	-0.8
Std. dev. reaction times	2.0	2.8	4.5	1.4	2.0	1.9	-1.3	1.1	2.1
Reaction time trials completed	0.4	0.5	1.8	1.3	-0.0	-0.1	-0.9	0.7	0.2
Reaction time trials AUC	0.4	0.5	1.8	1.4	-0.0	-0.1	-0.9	0.7	0.2
Social response proportion	0.6	0.6	1.7	1.3	0.8	0.2	-0.8	0.6	0.6
Social responses	0.1	0.1	0.3	0.3	0.6	-0.4	0.1	0.4	-0.1
Social time	0.2	0.3	0.6	0.8	0.6	0.2	-0.0	0.2	0.7
Conditioned locomotion	0.2	0.3	1.0	0.1	0.2	-0.2	0.8	-1.0	0.1
Cocaine response after cond. corrected	0.6	0.7	1.5	0.9	1.2	0.6	-0.5	0.7	1.0
Cocaine response after cond. not corrected	0.6	0.7	1.4	0.8	1.2	0.6	-0.6	0.9	0.8
Cocaine response before conditioning	0.1	0.1	0.4	0.0	-0.1	0.0	-0.6	0.7	-0.2
Saline control response	0.0	0.1	0.1	0.4	0.2	0.0	0.0	0.2	0.3
Condit. Reinf. active minus inactive responses	0.4	0.5	1.0	-0.4	-0.9	-1.0	0.5	-0.1	-1.0
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.3	-0.2	-0.4	-0.0	0.3	-0.2
Condit. Reinf. active responses	0.3	0.4	0.9	-0.7	-0.7	-0.6	0.1	0.1	-1.0
Condit. Reinf. inactive responses	0.8	0.9	1.7	-1.0	-1.1	-1.0	0.7	-0.4	-1.3
Condit. Reinf. lever presses	3.0	4.2	6.2	1.5	2.1	2.1	-2.5	2.0	1.9
Condit. Reinf. lever reinforcers received	0.1	0.2	0.3	-0.5	-0.3	-0.2	-0.3	0.6	-0.6
Pavlov. Cond. lever latency	2.2	3.0	4.4	-2.1	-1.5	-1.2	1.8	-2.1	-1.7
Pavlov. Cond. magazine entry latency	2.1	2.4	2.9	1.7	1.5	1.3	-1.5	1.5	1.7
Pavlov. Cond. change in total contacts	2.1	3.0	3.9	1.7	1.6	1.5	-2.0	1.9	1.6
Pavlov. Cond. index score	1.9	2.5	2.8	1.5	1.5	1.5	-1.7	1.7	1.6
Pavlov. Cond. latency score	1.5	1.9	2.1	1.3	1.4	1.3	-1.5	1.4	1.4
Pavlov. Cond. lever contacts	3.4	4.7	6.0	2.4	1.9	1.6	-2.4	2.4	2.0
Pavlov. Cond. magazine entry number	0.9	1.1	1.5	-1.2	-1.0	-0.8	0.9	-1.1	-1.2
Pavlov. Cond. intertrial magazine entries	0.9	1.2	2.2	-0.5	-1.3	-1.5	1.0	-0.5	-1.2
Pavlov. Cond. lever-magazine prob. diff.	1.9	2.4	2.9	1.4	1.5	1.5	-1.7	1.7	1.6
Pavlov. Cond. response bias	2.8	3.9	5.3	2.2	1.7	1.5	-2.1	2.3	1.9
Conditioned reinforcement - actives	0.1	0.1	0.2	0.5	0.3	-0.2	0.2	0.2	0.2
Conditioned reinforcement - inactives	0.8	0.9	1.8	-1.3	-0.9	-0.2	1.0	-1.1	-0.6
Conditioned locomotion	0.1	0.2	0.4	0.2	0.5	0.1	0.6	-0.4	0.5
Intermittent access intake day 1-15 change	0.8	0.8	1.7	1.3	-0.7	-1.3	0.1	0.7	-0.4
Intermittent access intake escalation	0.7	0.7	1.7	1.3	-0.5	-1.2	0.0	0.7	-0.3
Intermittent access intake escalation 2	0.5	0.5	1.2	0.9	-0.4	-1.1	0.1	0.9	-0.4
Intermitt. access day 1 inactive lever presses	1.0	1.0	2.9	-1.7	0.3	1.4	0.2	-1.0	0.3
Intermitt. access day 15 inactive lever presses	0.8	0.9	1.2	-1.1	-1.0	-0.8	0.9	-0.8	-1.1
Intermitt. access escalation Index	1.4	1.3	3.5	1.3	-0.2	0.0	-1.6	1.9	0.2
Intermittent access day 1 total infusions	0.1	0.1	0.2	0.2	0.4	0.1	0.2	-0.1	0.4
Intermittent access day 15 total infusions	0.4	0.5	1.8	1.3	0.1	-0.9	0.5	0.1	0.2
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.4	0.6	0.1	-0.3	0.4	-0.1	0.1
Intermittent access total infusions	0.3	0.3	0.8	0.9	0.5	-0.5	0.7	-0.4	0.4
Intermittent access day 1 locomotion	1.2	1.2	2.8	1.6	1.7	0.5	-0.2	0.3	1.3
Intermittent access day 15 total locomotion	1.0	1.0	2.8	1.7	1.1	0.4	-0.2	0.5	1.3
Intermittent access total locomotion	0.8	0.9	2.5	1.6	1.3	0.3	0.1	0.1	1.2
Intermittent access standard deviation	0.6	0.6	1.1	0.9	0.3	-1.1	1.1	-0.7	0.0
Cocaine induced anxiety	0.5	0.6	1.9	1.4	-0.3	-0.8	-0.5	0.8	-0.1
Post-drug Anxiety	1.0	1.1	2.2	-0.2	-1.4	-1.5	0.6	-0.4	-1.3
Baseline Anxiety	1.7	1.8	3.9	-2.0	-1.0	-0.5	1.4	-1.5	-1.1
Lifetime Intake	0.3	0.4	1.5	1.2	0.5	-0.3	0.2	0.2	0.6
Incentive Sensitization - Responses	1.0	1.0	2.1	1.4	1.1	0.4	-0.6	1.1	1.0
Incentive Sensitization - Breakpoint	1.1	1.1	2.3	1.5	1.1	0.5	-0.6	1.1	1.1
Progressive ratio test 1 active lever presses	1.4	1.4	2.9	0.1	-1.0	-1.7	1.6	-1.0	-1.0
Progressive ratio test 1 breakpoint	2.0	2.0	3.7	0.0	-1.3	-1.9	1.9	-1.3	-1.2
Progressive ratio test 1 inactive lever presses	0.4	0.4	1.2	0.1	-0.2	-0.8	1.1	-0.7	-0.3
Progressive ratio test 2 active lever presses	0.7	0.8	2.9	1.7	0.9	-0.3	0.0	0.5	0.8
Progressive ratio test 2 breakpoint	0.7	0.8	2.9	1.7	0.9	-0.3	0.1	0.4	0.7
Progressive ratio test 2 inactive lever presses	0.4	0.4	1.1	1.0	0.5	0.1	-0.3	0.9	0.6
Total sessions with >9 infusions	0.7	0.7	1.3	0.2	-1.0	-1.1	1.0	-0.6	-0.7
Short access day 1 total inactive lever presses	0.4	0.5	1.2	-0.3	1.1	0.9	0.1	-0.1	0.8
Short access day 10 total inactive lever presses	0.8	0.9	2.6	-1.6	0.2	1.5	-0.4	-0.4	0.3
Short access day 1 total infusions	0.1	0.1	0.5	0.7	-0.2	-0.1	-0.2	0.5	0.1
Short access day 10 total infusions	0.5	0.5	1.0	1.0	1.0	-0.1	0.6	-0.5	0.8
Short access total infusions	0.5	0.5	2.2	1.5	0.4	-0.1	-0.2	0.6	0.7
Short access day 1 locomotion	1.1	1.2	2.5	1.6	1.0	0.7	-0.8	0.9	1.3
Short access day 10 total locomotion	0.8	0.8	2.7	0.7	1.6	0.6	0.2	-0.3	1.1
Short access total locomotion	0.5	0.5	2.2	1.5	0.6	-0.4	0.3	-0.1	0.6
Compulsive drug intake	3.6	3.6	5.1	1.1	2.2	2.3	-1.9	1.5	2.2
One hour access (0.3 mA shock)	1.6	1.8	4.8	2.2	1.8	0.2	-0.5	0.9	1.4
One hour access (shock baseline)	0.8	0.9	2.3	0.5	-0.3	-1.5	1.4	-0.9	-0.6
Number of responses in last shaping day	1.0	1.0	2.6	-1.0	0.8	0.6	1.1	-1.6	0.4
Context. condit. distance diff. score	4.1	4.9	6.9	-2.6	-2.0	-1.6	2.3	-2.4	-2.2
Locomotion velocity, session 1	0.4	0.4	0.8	0.4	0.9	0.6	-0.5	0.5	0.7
Locomotion distance, session 1	0.3	0.4	0.7	-0.1	-0.6	-0.9	0.8	-0.3	-0.7
Locomotion velocity, session 2	0.3	0.4	0.8	0.8	-0.4	-0.0	-0.9	0.9	0.1
Locomotion distance, session 2	0.4	0.6	1.3	1.2	0.4	0.4	-0.8	1.0	0.6
Locomotion velocity, session 3	0.0	0.1	0.1	0.3	0.0	-0.4	0.2	-0.2	-0.1
Locomotion distance, session 3	0.0	0.0	0.0	-0.1	0.1	-0.0	0.2	-0.0	-0.0
Stereotopy head waving bouts, day 3	0.6	0.7	1.3	-0.2	-1.1	-1.1	0.5	-0.4	-1.1
Stereotopy head waving duration, day 3	0.7	0.9	2.1	0.1	-1.4	-1.3	0.5	-0.2	-1.0
Locomotion velocity, session 7	0.8	0.9	1.6	-0.5	-1.2	-1.2	0.6	-0.6	-1.3
Locomotion distance, session 7	0.4	0.5	0.9	-0.5	-0.8	-0.8	0.5	-0.6	-0.9
Stereotopy head waving bouts, day 7	0.4	0.4	0.8	0.4	0.6	0.9	-0.7	0.3	0.8
Stereotopy head waving duration, day 7	1.1	1.3	1.8	1.1	1.0	1.2	-1.2	1.1	1.4
Locomotion velocity, session 8	0.2	0.2	0.3	-0.4	-0.5	-0.4	0.4	-0.3	-0.4
Locomotion distance, session 8	0.6	0.9	1.2	-0.7	-0.9	-1.0	0.9	-0.8	-1.1
Degree of sensitization distance	0.0	0.0	0.1	-0.4	-0.0	0.2	-0.1	-0.3	-0.1
Degree of sensitization stereotypy	1.0	1.1	1.7	0.9	1.1	1.1	-1.0	0.8	1.3
Condit. Reinf. active minus inactive responses	0.7	0.8	1.9	0.9	1.4	0.7	-0.6	0.5	1.0
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.5	0.5	1.2	0.4	-0.1	0.2	0.8
Condit. Reinf. active responses	1.6	1.9	3.9	1.3	2.0	1.3	-1.0	0.8	1.6
Condit. Reinf. inactive responses	0.7	0.9	1.4	0.9	1.2	0.8	-0.8	0.7	1.1
Incentive salience index mean	1.1	1.3	3.0	1.2	1.7	0.9	-0.7	0.6	1.3
Condit. Reinf. lever presses	0.2	0.3	1.0	0.6	1.0	0.3	-0.1	0.2	0.6
Time in familiar zone, hab. session 1	3.0	2.8	4.7	-1.5	-1.5	-1.4	2.2	-1.9	-1.4
Time in novel zone, hab. session 1	5.3	5.1	7.8	1.8	2.2	2.4	-2.8	2.0	2.3
Total zone transitions, hab. session 1	0.7	1.0	2.0	-0.1	-0.9	-1.4	1.3	-0.8	-1.0
Total locomotion distance, hab. session 1	0.4	0.5	0.9	-0.5	-0.9	-0.6	0.6	-0.6	-0.9
Locomotion velocity, hab. session 1	0.2	0.3	0.5	-0.2	-0.7	-0.7	0.5	-0.3	-0.7
Time in familiar zone, hab. session 2	0.5	0.5	1.6	-0.4	-0.1	-0.5	1.3	-0.9	-0.2
Time in novel zone, hab. session 2	0.7	0.7	1.9	0.6	0.4	0.8	-1.4	1.0	0.6
Total zone transitions, hab. session 2	3.3	4.3	8.5	-0.3	-2.3	-2.9	2.1	-1.3	-2.3
Total locomotion distance, hab. session 2	2.4	3.2	5.4	-0.6	-2.2	-2.3	1.7	-1.2	-2.1
Locomotion velocity, hab. session 2	2.1	2.8	5.0	-0.4	-2.1	-2.2	1.5	-1.0	-2.0
Novel to familiar place preference ratio	0.8	0.8	1.3	0.6	0.9	1.2	-0.9	0.6	1.1
Novelty place preference	0.4	0.4	0.9	0.2	0.5	0.9	-0.8	0.5	0.7
Time in novel zone, NPP test	0.5	0.5	1.2	0.1	0.6	1.1	-0.8	0.4	0.8
Total zone transitions, NPP test	0.8	1.2	2.9	-0.1	-1.1	-1.7	1.2	-0.5	-1.2
Total locomotion distance, NPP test	0.5	0.6	1.2	-0.2	-1.1	-1.1	0.5	-0.2	-1.1
Locomotion velocity, NPP test	0.4	0.6	1.3	-0.0	-1.0	-1.1	0.5	-0.1	-1.0
Pavlov. Cond. lever latency	0.9	1.2	3.3	-0.2	-1.8	-1.3	0.2	0.2	-1.3
Pavlov. Cond. magazine entry latency	0.1	0.1	0.4	0.3	0.4	-0.3	0.6	-0.3	0.2
Pavlov. Cond. change in total contacts	0.7	0.8	2.1	0.7	1.5	0.9	-0.3	-0.1	1.1
Pavlov. Cond. index score	0.4	0.5	1.7	0.2	1.3	0.7	0.2	-0.2	0.9
Pavlov. Cond. latency score	0.5	0.6	1.8	0.3	1.3	0.8	0.2	-0.2	1.0
Pavlov. Cond. lever contacts	0.4	0.5	1.8	0.1	1.3	0.7	0.2	-0.4	0.8
Pavlov. Cond. magazine entry number	0.2	0.2	0.5	-0.4	-0.4	0.4	-0.7	0.2	-0.1
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.5	1.2	-0.3	-1.0	-0.2	0.5	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.8	0.3	1.3	0.7	0.2	-0.1	0.9
Pavlov. Cond. response bias	0.2	0.3	0.9	0.0	1.0	0.2	0.6	-0.4	0.4
Bone: apparent density	0.2	0.3	0.9	-0.4	-0.4	-0.4	-0.4	0.9	-0.7
Bone surface	1.3	2.2	4.3	0.3	1.3	1.7	-2.1	1.7	1.0
Bone volume	0.5	0.8	2.1	-0.0	0.5	0.8	-1.4	1.5	0.3
Bone: connectivity density	1.8	2.9	4.5	0.6	1.8	1.8	-2.1	2.0	1.4
Bone: cortical apparent density	4.1	5.4	11.4	-0.6	-2.7	-3.4	2.2	-1.1	-2.8
Bone: cortical area	0.3	0.4	1.1	1.1	0.4	0.3	-0.6	0.6	0.7
Bone: cortical porosity	0.3	0.3	0.7	0.0	0.7	0.9	-0.4	-0.1	0.8
Bone: cortical porosity	0.5	0.6	1.2	0.0	0.9	1.1	-0.3	-0.2	1.1
Bone: cortical thickness	0.2	0.3	0.8	-0.0	-0.4	-0.6	0.9	-0.7	-0.2
Bone: cortical thickness	0.3	0.4	0.9	-0.5	-0.3	-0.2	0.9	-1.0	-0.4
Bone: cortical tissue density	4.0	5.3	11.1	-0.6	-2.6	-3.3	2.1	-1.1	-2.7
Bone: elastic displacement	0.7	0.8	1.2	-1.1	-0.8	-0.7	1.0	-0.9	-0.9
Bone: elastic work	1.1	1.5	2.1	-1.2	-1.1	-1.0	1.4	-1.3	-1.1
Bone: endosteal estimation	0.3	0.7	1.8	-0.2	0.6	1.0	-1.4	0.9	0.3
Bone: endosteal perimeter	1.3	2.7	5.6	1.3	1.0	1.4	-2.4	2.1	1.3
Bone: final force	0.2	0.4	1.0	0.2	-0.8	-1.0	0.5	-0.0	-0.7
Bone: final moment	0.0	0.0	0.1	0.2	-0.2	-0.3	0.1	0.1	-0.2
Bone: marrow area	0.3	0.6	1.7	-0.1	0.6	0.9	-1.3	0.9	0.3
Bone: maximum diameter	0.8	1.5	2.4	1.6	0.9	0.8	-1.4	1.4	1.2
Bone: maximum force	0.0	0.1	0.2	0.3	-0.3	-0.5	0.1	0.2	-0.2
Bone: maximum moment	0.1	0.1	0.1	0.3	0.4	0.3	-0.3	0.4	0.3
Bone: minimum diameter	1.1	2.0	2.8	0.8	1.3	1.6	-1.7	1.5	1.4
Bone: periosteal estimation	0.4	0.8	1.6	0.6	0.7	0.9	-1.3	0.9	0.7
Bone: periosteal perimeter	1.2	2.0	3.4	1.6	0.9	0.9	-1.7	1.8	1.2
Bone: post-yield work	1.1	1.5	2.4	1.1	1.5	1.3	-1.2	0.8	1.4
Bone: stiffness	0.1	0.1	0.3	0.0	-0.5	-0.5	0.1	0.1	-0.4
Bone: tissue strength	1.6	1.5	2.4	1.6	1.3	0.7	-1.2	1.3	1.2
Bone: trabecular number	0.1	0.2	0.5	-0.6	-0.2	-0.1	-0.2	0.7	-0.4
Bone: trabecular spacing	0.2	0.3	1.0	-0.4	0.1	-0.1	0.8	-1.0	-0.1
Bone: trabecular thickness	0.2	0.2	0.4	0.1	-0.6	-0.5	-0.1	0.4	-0.5
Bone: trabecular tissue density	9.2	12.9	25.3	-1.1	-4.6	-5.0	3.0	-1.4	-4.3
Breakpoint value in progressive ratio session	0.6	0.7	1.3	-1.0	-0.4	-0.7	0.8	-1.1	-0.8
Distance traveled before self-admin	0.4	0.4	1.1	-1.0	-0.1	0.3	0.4	-1.0	-0.2
Distance traveled after self-admin	0.7	0.8	1.4	0.5	1.0	1.0	-1.2	0.8	0.8
Delta time in closed arm before/after self-admin	0.3	0.3	0.6	-0.4	0.4	0.7	0.3	-0.8	0.4
Delta time in open arm before/after self-admin	2.0	1.9	3.9	2.0	1.1	0.7	-1.4	1.5	1.3
Diff in mean of infusions in LGA sessions	0.7	0.8	1.6	-1.3	-0.5	-0.3	1.1	-1.1	-0.7
Extinction: sum of active levers before priming	2.2	2.2	4.1	-2.0	-1.6	-0.7	1.2	-1.6	-1.5
Active lever presses in extinction session 6	0.9	0.9	2.5	-1.3	0.4	0.3	1.0	-1.6	-0.1
Delta distance traveled before/after self-admin	2.3	2.4	3.4	1.5	1.5	1.2	-1.7	1.8	1.5
Delta ambulatory time before/after self-admin	2.1	2.3	3.7	1.6	1.3	0.9	-1.7	1.9	1.3
Time in closed arm before self-admin	0.8	0.9	2.7	1.6	0.5	-0.5	-0.7	1.3	0.3
Time in closed arm after self-admin	0.1	0.1	0.3	0.6	0.4	0.0	0.0	-0.0	0.4
Time in open arm before self-admin	0.5	0.5	1.7	-1.3	0.1	0.8	0.3	-0.8	0.1
Time in open arm after self-admin	1.4	1.5	2.4	0.7	1.3	1.6	-1.3	0.9	1.4
Sum of active levers in priming session hrs 5-6	4.3	4.2	7.7	-2.8	-1.5	-1.1	2.0	-2.5	-2.0
Time to tail flick, vehicle, before self-admin	1.2	1.2	2.6	0.4	1.3	1.6	-0.7	0.0	1.5
Time to tail flick, vehicle, after self-admin	0.8	0.8	1.4	0.7	1.0	0.9	-1.2	0.9	0.8
Time to tail flick, test, before self-admin	0.0	0.0	0.1	-0.2	0.0	0.1	-0.3	0.4	0.0
Time to tail flick, test, after self-admin	0.2	0.2	0.4	-0.7	-0.6	0.2	-0.6	0.2	-0.5
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.6	-0.3	-1.1	-1.1	0.1	0.2	-1.3
Delta time to tail flick, test, before/after SA	0.3	0.3	0.9	0.4	0.2	0.6	-0.9	0.6	0.3
Ambulatory time before self-admin	1.3	1.3	3.6	-1.9	-0.8	0.1	1.0	-1.5	-0.7
Ambulatory time after self-admin	0.8	0.9	1.8	0.4	1.3	1.1	-1.0	0.6	1.0
Total heroin consumption	0.8	0.9	1.6	-0.7	-0.7	-1.3	0.9	-0.8	-1.2
Area under the delay curve	0.2	0.3	0.5	-0.1	-0.7	-0.5	0.6	-0.5	-0.4
Delay disc. indifference point, 0s delay	3.6	3.9	5.7	-2.0	-2.4	-1.6	2.1	-1.8	-1.9
Delay disc. indifference point, 16s delay	1.2	1.2	2.2	1.0	1.5	1.2	-0.6	0.3	1.5
Delay disc. indifference point, 2s delay	1.2	1.3	2.3	-1.5	-1.5	-0.5	0.9	-1.0	-1.2
Delay disc. indifference point, 24s delay	0.2	0.2	0.6	0.8	0.4	-0.2	0.0	-0.1	0.3
Delay disc. indifference point, 4s delay	2.1	2.2	4.1	-0.9	-2.0	-1.6	1.4	-1.1	-1.6
Delay disc. indifference point, 8s delay	0.8	0.8	1.5	-0.1	-1.2	-1.1	1.0	-0.6	-0.8
Delay discount exponential model param	0.2	0.2	0.4	0.1	0.7	0.4	-0.6	0.5	0.3
Delay discount hyperbolic model param	0.4	0.4	0.8	0.3	0.9	0.6	-0.8	0.6	0.5
Fecal boli incidents, locomotor time 1	0.3	0.3	1.0	1.0	0.6	-0.1	0.0	0.2	0.5
Change in fecal boli incidents, locomotor task	0.6	0.6	1.2	-0.8	-1.1	-0.3	0.4	-0.8	-0.8
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	-0.0	-0.0	0.4	0.0	-0.4	0.3
Bouts of movement, locomotor time 1	0.9	1.0	2.4	-1.5	0.7	1.0	0.8	-1.3	0.4
Total resting periods, locomotor time 1	0.7	0.8	2.5	-1.6	0.4	1.0	0.5	-0.8	0.3
Rest time, locomotor task time 1	0.4	0.4	1.3	-1.2	-0.4	0.3	0.3	-0.6	-0.4
Distance moved, locomotor task time 1	0.2	0.2	0.3	0.3	-0.6	-0.5	-0.2	0.5	-0.3
Vertical activity count, locomotor time 1	0.1	0.1	0.1	0.3	-0.4	-0.3	-0.2	0.3	-0.2
Time >=10cm from walls, locomotor time 2	3.0	3.2	4.2	-1.6	-2.1	-1.5	2.0	-1.7	-1.7
Bouts of movement, locomotor time 2	0.7	0.8	1.8	-0.0	1.2	1.3	-0.2	-0.2	1.2
Total resting periods, locomotor time 2	0.7	0.8	1.6	0.1	1.3	1.3	-0.3	-0.1	1.2
Rest time, locomotor task time 2	0.2	0.2	0.5	-0.0	0.6	0.7	-0.3	-0.3	0.4
Distance moved, locomotor task time 2	1.4	1.7	3.6	-1.0	-1.9	-1.5	0.8	0.0	-1.6
Vertical activity count, locomotor time 2	0.8	0.9	1.8	-1.0	-1.3	-0.9	0.7	-0.3	-1.1
Weight adjusted by age	1.1	1.3	2.2	0.8	0.6	1.3	-1.5	1.2	1.1
Seeking ratio, delayed vs. immediate footshock	1.2	1.4	5.1	-2.3	-0.2	0.6	0.7	-1.5	-0.4
Locomotion in novel chamber	0.3	0.4	0.8	-0.0	0.9	0.9	-0.5	-0.3	0.7
Locomotion in novel chamber post-restriction	0.4	0.5	1.3	1.1	0.9	-0.2	0.5	-0.4	0.6
Progressive ratio	0.2	0.2	0.7	0.8	-0.3	-0.7	-0.1	0.3	-0.2
Food seeking constrained by brief footshock	3.4	4.1	5.9	-1.2	-2.4	-2.3	2.0	-1.7	-2.3
Seeking ratio, punishment vs. effort	1.0	1.3	1.8	-1.3	-1.2	-0.8	1.2	-1.0	-1.2
Run reversals in cocaine runway, females	0.5	0.5	2.2	-1.5	-0.4	0.4	0.4	-0.5	-0.3
Run reversals in cocaine runway, males	0.4	0.4	0.7	0.3	0.8	0.9	-0.4	0.1	0.8
Latency to leave start box in cocaine runway	0.5	0.5	1.0	-0.4	-1.0	-0.7	0.5	-0.7	-0.9
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	0.5	-0.2	-0.3	-0.1	0.1	-0.1
Latency to leave start box in cocaine runway, M	1.5	1.4	2.1	-1.5	-1.4	-0.7	0.9	-1.2	-1.3
Cd content in liver	0.9	0.9	2.8	-0.8	1.1	1.7	-0.5	0.0	0.8
Co content in liver	1.2	1.4	4.9	-2.2	-0.7	-0.0	0.8	-1.2	-1.0
Cu content in liver	0.2	0.2	0.4	-0.1	-0.3	-0.6	0.5	-0.5	-0.4
Fe content in liver	0.5	0.6	1.4	-0.0	0.8	1.2	-0.7	0.7	0.8
K content in liver	0.9	0.9	1.6	-0.5	-1.1	-1.3	0.7	-0.5	-1.2
Mg content in liver	1.6	1.7	4.8	2.2	0.6	0.0	-1.3	1.6	0.9
Mn content in liver	0.1	0.1	0.4	0.0	0.1	-0.2	0.7	-0.6	0.0
Na content in liver	2.6	2.8	4.9	-1.2	-2.0	-2.0	1.2	-1.0	-2.2
Rb content in liver	0.3	0.4	0.8	-0.2	-0.4	-0.9	0.9	-0.5	-0.6
Se content in liver	0.3	0.3	1.1	-0.2	0.7	1.0	-0.4	-0.1	0.5
Sr content in liver	0.2	0.1	0.4	-0.2	0.3	0.4	-0.6	0.4	0.1
Zn content in liver	1.3	1.5	2.8	1.7	1.1	0.6	-1.3	1.2	1.2