RT1-N2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000050159 0.13 0.09 1.9e-13 0.12 0.07 0.12 0.12 1.9e-13 2.6e-08 8.3e-13 3.8e-13
2 Adipose alternative polyA ENSRNOT00000086026 0.13 0.08 7.0e-13 0.12 0.07 0.11 0.11 7.0e-13 6.4e-08 3.1e-12 1.5e-12
3 Adipose gene expression ENSRNOG00000029386 0.54 0.08 0.0e+00 0.66 0.5 0.66 0.33 1.8e-96 4.5e-63 7.7e-99 1.2e-37
4 Adipose isoform ratio ENSRNOT00000050159 0.11 0.07 1.9e-12 0.12 0.05 0.1 0.11 1.5e-13 1.2e-06 7.0e-11 9.3e-12
5 Adipose isoform ratio ENSRNOT00000086026 0.1 0.07 4.4e-11 0.11 0.05 0.08 0.1 2.8e-12 6.1e-06 1.4e-09 9.1e-11
6 Adipose intron excision ratio chr20:2643474:2691325 0.05 0.04 6.4e-04 0.03 0.01 0.01 0.02 4.3e-04 1.2e-02 1.0e-02 2.2e-03
7 Adipose intron excision ratio chr20:2663953:2664131 0.11 0.07 3.2e-05 0.03 0.02 0.02 0.02 6.7e-04 1.6e-03 1.2e-03 1.1e-03
8 Adipose intron excision ratio chr20:2663953:2691325 0.05 0.04 7.0e-04 0.03 0.01 0.01 0.02 4.7e-04 1.2e-02 1.3e-02 2.4e-03
9 BLA gene expression ENSRNOG00000029386 0.72 0.07 0.0e+00 0.58 0.6 0.61 0.62 2.2e-37 2.9e-39 1.2e-40 6.2e-42
10 Brain gene expression ENSRNOG00000029386 0.55 0.03 0.0e+00 0.62 0.67 0.67 0.67 7.2e-74 1.3e-83 3.6e-84 2.8e-84
11 Eye gene expression ENSRNOG00000029386 0.63 0.14 6.3e-07 0.12 0.16 0.13 0.15 6.9e-03 2.1e-03 5.5e-03 2.5e-03
12 IL gene expression ENSRNOG00000029386 0.87 0.07 0.0e+00 0.5 0.49 0.52 0.53 1.0e-13 1.7e-13 1.6e-14 6.1e-15
13 Liver alternative polyA ENSRNOT00000050159 0.39 0.16 0.0e+00 0.38 0.37 0.37 0.38 2.8e-44 1.4e-43 4.0e-43 1.4e-44
14 Liver gene expression ENSRNOG00000029386 0.49 0.07 0.0e+00 0.6 0.6 0.61 0.61 3.4e-83 2.2e-84 1.2e-85 6.6e-85
15 Liver isoform ratio ENSRNOT00000050159 0.19 0.1 0.0e+00 0.18 0.2 0.21 0.21 1.0e-19 3.3e-21 1.9e-22 1.5e-22
16 Liver intron excision ratio chr20:2641599:2641703 0.06 0.05 2.0e-03 0.03 0.02 0.01 0.03 4.2e-04 1.5e-03 8.7e-03 5.2e-04
17 Liver intron excision ratio chr20:2641599:2641768 0.05 0.05 3.3e-03 0.01 0.01 0.01 0.01 6.7e-03 1.7e-02 1.6e-02 9.1e-03
18 Liver intron excision ratio chr20:2644289:2644413 0.34 0.13 0.0e+00 0.09 0.09 0.09 0.09 1.2e-10 3.6e-10 5.5e-10 4.1e-10
19 Liver intron excision ratio chr20:2664766:2664890 0.32 0.13 0.0e+00 0.09 0.09 0.09 0.09 2.1e-10 7.1e-10 9.7e-10 9.5e-10
20 NAcc alternative polyA ENSRNOT00000050159 0.59 0.16 0.0e+00 0.28 0.1 0.25 0.25 8.5e-21 5.3e-08 2.3e-18 9.5e-19
21 NAcc gene expression ENSRNOG00000029386 0.71 0.08 0.0e+00 0.58 0.28 0.62 0.06 1.4e-52 2.7e-21 5.7e-59 5.1e-05
22 OFC alternative polyA ENSRNOT00000050159 0.32 0.17 6.7e-06 0.28 0.28 0.26 0.23 2.0e-07 3.0e-07 6.9e-07 3.1e-06
23 OFC gene expression ENSRNOG00000029386 0.81 0.1 0.0e+00 0.48 0.46 0.42 0.42 5.1e-13 1.8e-12 3.3e-11 3.8e-11
24 PL gene expression ENSRNOG00000029386 0.83 0.05 0.0e+00 0.69 0.37 0.7 0.01 9.8e-72 1.2e-29 7.9e-74 9.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
BMI with tail1.54.87.62.4-2.42.72.4-2.40.1-0.10.12.72.72.72.82.52.72.70.1-0.00.00.02.62.82.52.52.7
BMI without tail3.16.510.02.9-2.93.02.9-2.9-0.70.9-0.72.93.02.92.93.03.03.0-0.91.00.00.03.22.93.13.13.0
Body weight5.623.633.75.6-5.65.75.6-5.6-2.52.3-2.55.65.75.65.55.75.65.5-2.42.50.00.05.85.35.75.75.8
Epididymis fat weight3.27.626.41.3-1.32.01.3-1.35.1-4.85.12.32.02.42.61.52.32.54.7-4.30.00.01.53.11.51.41.8
Glucose2.23.414.1-0.40.4-1.0-0.40.4-3.53.7-3.5-1.2-1.0-1.3-1.4-0.5-1.1-1.3-3.73.80.00.0-0.5-1.6-0.5-0.6-0.7
Heart weight0.10.10.30.3-0.30.40.3-0.3-0.30.3-0.30.40.30.40.40.30.40.3-0.50.60.00.00.50.40.30.50.5
Left kidney weight3.49.614.13.7-3.73.73.7-3.7-1.20.9-1.23.63.63.63.63.63.63.5-1.11.30.00.03.53.53.63.73.8
Right kidney weight3.19.012.83.6-3.63.43.6-3.6-2.22.1-2.23.23.33.23.23.43.23.2-2.32.30.00.03.22.93.43.53.5
Tail length4.814.419.24.1-4.13.94.1-4.1-4.34.3-4.33.53.83.53.44.13.63.4-4.34.40.00.04.13.04.14.34.1
Length with tail4.215.620.54.4-4.44.24.4-4.4-3.83.6-3.84.14.24.03.94.44.13.8-3.63.80.00.04.43.54.44.54.4
Length without tail2.96.48.82.9-2.92.92.9-2.9-2.11.8-2.13.02.92.82.82.92.82.6-1.71.80.00.02.82.52.82.82.9
Liver weight, left1.11.76.31.1-1.10.81.1-1.1-2.12.5-2.10.90.80.70.61.00.80.7-2.52.50.00.01.10.61.00.91.0
Liver weight, right3.96.512.92.6-2.62.32.6-2.6-3.63.5-3.62.12.32.02.02.62.12.0-3.53.60.00.02.71.72.52.62.5
Parametrial fat weight1.83.55.52.3-2.32.32.3-2.30.00.10.02.32.32.32.22.32.22.1-0.20.10.00.02.12.22.02.12.2
Retroperitoneal fat weight0.41.32.21.4-1.41.21.4-1.4-0.10.1-0.11.51.21.31.21.31.31.4-0.20.40.00.01.41.31.41.11.3
Intraocular pressure0.91.32.5-1.61.6-1.2-1.61.60.5-0.30.5-1.3-1.2-1.2-1.2-1.3-1.2-1.40.5-0.40.00.0-1.2-1.1-1.6-1.2-1.2
Extensor digitorum longus weight0.10.51.80.5-0.50.20.5-0.5-1.31.3-1.30.20.20.10.10.40.20.2-1.31.20.4-0.40.4-0.00.50.40.3
Soleus weight1.33.816.61.0-1.00.51.0-1.0-4.04.1-4.00.30.50.30.20.90.40.3-4.04.00.9-0.90.9-0.21.11.00.8
Tibialis anterior weight0.20.63.0-0.00.00.1-0.00.01.7-1.51.70.20.20.20.3-0.00.20.31.6-1.70.1-0.1-0.10.50.1-0.00.1
Tibia length2.87.810.72.7-2.72.62.7-2.7-3.33.3-3.32.42.62.52.42.82.52.3-3.23.23.0-3.02.92.12.82.92.8
Number of licking bursts0.30.41.0-0.40.4-0.5-0.40.4-1.00.9-1.0-0.5-0.6-0.6-0.7-0.4-0.6-0.6-0.90.8-0.30.3-0.4-0.7-0.4-0.4-0.5
Food consumed during 24 hour testing period1.11.32.81.1-1.10.91.1-1.1-1.71.7-1.70.80.90.80.81.10.90.8-1.71.61.0-1.01.10.61.11.11.0
Times rat made contact with spout1.61.83.9-1.31.3-1.2-1.31.32.0-1.72.0-1.0-1.1-1.0-1.0-1.3-1.1-1.01.7-1.7-1.31.3-1.3-0.8-1.4-1.4-1.3
Mean time between licks in bursts0.81.16.4-0.10.1-0.4-0.10.1-2.52.0-2.5-0.4-0.4-0.6-0.6-0.1-0.5-0.6-2.02.00.1-0.1-0.1-0.8-0.1-0.0-0.2
Mean num. licks in bursts0.50.63.6-0.30.3-0.1-0.30.31.9-1.51.90.0-0.00.10.1-0.30.00.11.5-1.3-0.40.4-0.30.3-0.3-0.3-0.1
Std. dev. time between licks in bursts0.91.06.20.4-0.40.00.4-0.4-2.51.8-2.5-0.10.0-0.2-0.30.3-0.1-0.1-1.82.00.4-0.40.4-0.40.40.30.2
Water consumed over 24 hours0.10.10.40.1-0.1-0.00.1-0.1-0.50.6-0.5-0.0-0.0-0.1-0.10.1-0.0-0.0-0.60.50.1-0.10.1-0.10.00.10.0
Indifference point 0 sec0.71.13.80.9-0.90.80.9-0.91.7-1.91.70.90.60.80.80.80.91.01.9-1.80.00.00.71.00.40.50.6
Indifference point AUC2.02.43.61.7-1.71.81.7-1.7-0.60.8-0.61.91.81.81.91.81.81.7-0.70.70.00.01.91.71.71.81.9
Indifference point function ln k0.40.61.1-0.80.8-0.9-0.80.8-0.60.3-0.6-1.0-0.9-0.9-0.9-0.8-0.9-0.9-0.40.40.00.0-0.9-1.0-0.8-0.7-0.8
Indifference point function log k0.40.61.1-0.80.8-0.9-0.80.8-0.60.3-0.6-1.0-0.9-0.9-0.9-0.8-0.9-0.9-0.40.40.00.0-0.9-1.0-0.8-0.7-0.8
Delay discounting total patch changes 0 sec0.91.54.61.0-1.01.01.0-1.01.9-2.21.91.10.81.11.10.91.11.22.1-2.00.00.00.81.20.60.70.8
Delay discounting total patch changes 12 sec1.11.42.91.1-1.11.11.1-1.11.7-1.51.71.31.01.11.20.91.21.21.7-1.70.00.00.81.30.70.80.9
Delay discounting total patch changes 18 sec1.31.88.90.1-0.10.40.1-0.12.7-2.72.70.60.30.50.60.20.50.62.9-3.00.00.00.20.80.10.00.1
Delay discounting total patch changes 24 sec1.62.09.5-0.60.6-0.6-0.60.62.8-3.12.8-0.1-0.6-0.4-0.4-0.6-0.4-0.13.0-2.80.00.0-0.6-0.1-0.6-1.0-0.8
Delay discounting total patch changes 6 sec1.01.65.10.7-0.70.90.7-0.72.3-2.22.31.10.81.01.10.81.01.12.2-2.20.00.00.81.30.50.70.7
Delay discounting time to switch 0 sec0.40.62.2-0.50.5-0.7-0.50.51.5-1.21.5-0.4-0.6-0.5-0.5-0.6-0.6-0.41.2-1.40.00.0-0.7-0.2-0.6-0.8-0.7
Delay discounting water rate 0 sec0.30.51.20.6-0.61.00.6-0.60.1-0.50.10.80.90.90.90.60.90.70.3-0.20.00.00.60.80.71.10.9
Delay discounting water rate 12 sec0.30.41.6-0.70.7-0.2-0.70.71.0-1.31.0-0.2-0.3-0.1-0.2-0.5-0.2-0.51.2-1.10.00.0-0.5-0.1-0.8-0.1-0.2
Delay discounting water rate 18 sec0.20.30.50.7-0.70.60.7-0.7-0.50.2-0.50.50.70.60.50.70.60.5-0.40.40.00.00.50.40.50.70.6
Delay discounting water rate 24 sec1.21.73.31.3-1.31.71.3-1.3-0.1-0.3-0.11.61.71.71.71.31.61.40.3-0.50.00.01.31.51.41.81.6
Delay discounting water rate 6 sec0.20.31.6-0.40.40.1-0.40.41.0-1.31.00.00.10.10.2-0.20.0-0.21.2-1.20.00.0-0.40.1-0.30.1-0.0
Locomotor activity2.03.29.71.7-1.71.11.7-1.7-3.03.0-3.00.91.11.00.81.61.01.0-3.13.10.00.01.50.61.51.41.3
Locomotor testing distance0.40.73.50.8-0.80.30.8-0.8-1.31.6-1.30.20.30.30.20.70.30.4-1.81.90.00.00.70.20.50.40.4
Locomotor testing rearing0.81.23.21.2-1.20.71.2-1.2-1.71.7-1.70.60.70.70.61.10.70.8-1.71.80.00.01.10.50.90.80.8
Light reinforcement 10.10.21.20.1-0.10.30.1-0.11.1-0.81.10.30.30.40.40.10.30.20.7-0.70.00.00.00.50.10.30.4
Light reinforcement 20.60.81.41.0-1.01.01.0-1.0-0.91.1-0.90.90.90.90.90.90.90.8-1.21.00.00.00.90.81.00.91.1
Reaction time number correct0.60.84.90.1-0.10.30.1-0.11.6-2.11.60.20.30.40.40.10.40.42.1-2.20.00.00.00.50.10.20.1
Reaction time mean minus median1.82.411.60.3-0.3-0.40.3-0.3-3.43.2-3.4-0.4-0.3-0.6-0.70.1-0.5-0.4-3.23.20.00.00.1-0.90.2-0.1-0.1
Reaction time mean minus median AUC1.21.57.5-0.10.1-0.6-0.10.1-2.72.4-2.7-0.6-0.6-0.7-0.8-0.2-0.6-0.6-2.42.40.00.0-0.2-1.1-0.2-0.3-0.4
Reaction time num false alarms0.30.40.80.7-0.70.80.7-0.7-0.50.6-0.50.60.70.80.70.60.70.5-0.60.80.00.00.50.60.70.80.9
Reaction time num false alarms AUC0.60.81.31.0-1.01.01.0-1.0-0.60.8-0.60.91.01.00.90.91.00.8-0.81.00.00.00.80.90.91.01.2
Reaction time trials correct on left0.60.84.90.1-0.10.30.1-0.11.6-2.11.60.20.30.40.40.10.40.42.1-2.20.00.00.00.50.10.20.1
Reaction time trials on left0.50.84.40.2-0.20.30.2-0.21.5-2.01.50.20.30.40.40.10.40.42.0-2.10.00.00.00.50.10.20.1
Reaction time mean1.72.39.9-0.40.4-0.8-0.40.4-2.93.1-2.9-1.0-0.8-1.0-1.1-0.4-0.9-1.0-3.13.10.00.0-0.4-1.3-0.4-0.5-0.6
Reaction time mean AUC1.82.310.0-0.30.3-0.8-0.30.3-3.03.2-3.0-1.0-0.8-1.0-1.1-0.4-0.9-0.9-3.23.10.00.0-0.4-1.3-0.4-0.5-0.6
Median of all reaction times1.11.56.2-0.50.5-0.8-0.50.5-2.22.5-2.2-1.0-0.8-0.9-1.0-0.5-0.9-1.0-2.52.40.00.0-0.5-1.1-0.6-0.5-0.6
Reaction time omissions1.11.56.6-0.20.2-0.6-0.20.2-2.52.4-2.5-0.7-0.6-0.7-0.8-0.3-0.6-0.7-2.32.60.00.0-0.2-0.9-0.2-0.2-0.3
Reaction time false alarm rate0.71.04.20.8-0.80.70.8-0.8-1.51.9-1.50.50.60.60.50.70.60.5-1.92.00.00.00.60.40.70.80.9
Reaction time premature initiation rate1.01.42.61.2-1.21.51.2-1.2-0.00.1-0.01.51.51.51.51.31.51.5-0.1-0.10.00.01.31.41.61.41.4
Reaction time premature initiations1.42.03.31.4-1.41.71.4-1.40.8-1.00.81.71.81.71.81.41.71.71.0-1.20.00.01.41.71.71.51.5
Std. dev. reaction times2.02.712.80.4-0.4-0.30.4-0.4-3.63.5-3.6-0.4-0.3-0.5-0.60.2-0.4-0.3-3.53.60.00.00.2-0.80.30.10.0
Reaction time trials completed0.50.84.40.2-0.20.30.2-0.21.5-2.01.50.20.30.40.40.10.40.42.0-2.10.00.00.00.50.10.20.1
Reaction time trials AUC0.50.84.40.1-0.10.30.1-0.11.6-2.01.60.20.20.30.40.00.30.32.0-2.10.00.0-0.00.40.00.20.0
Social response proportion0.20.31.20.5-0.50.20.5-0.5-1.00.8-1.00.10.20.10.10.30.20.2-0.81.10.00.00.40.10.40.40.2
Social responses0.10.20.50.5-0.50.50.5-0.5-0.40.3-0.40.30.40.40.50.40.50.4-0.30.50.00.00.40.50.40.70.4
Social time1.31.88.80.5-0.50.10.5-0.5-2.73.0-2.7-0.10.1-0.1-0.20.4-0.0-0.1-3.02.90.00.00.4-0.50.50.20.3
Conditioned locomotion0.80.91.21.0-1.00.91.0-1.0-0.90.9-0.90.91.00.80.81.00.90.9-0.91.00.9-0.91.00.71.11.01.0
Cocaine response after cond. corrected0.50.60.7-0.80.8-0.8-0.80.80.3-0.50.3-0.7-0.8-0.7-0.7-0.8-0.8-0.70.5-0.7-0.90.9-0.8-0.7-0.8-0.8-0.9
Cocaine response after cond. not corrected0.30.31.10.4-0.40.30.4-0.4-1.11.0-1.10.30.30.20.20.40.30.2-1.00.80.4-0.40.40.10.40.50.4
Cocaine response before conditioning5.16.37.62.7-2.72.52.7-2.7-2.22.4-2.22.42.52.32.32.72.42.3-2.42.42.7-2.72.72.22.62.82.7
Saline control response1.21.62.51.1-1.11.31.1-1.11.2-1.31.21.41.31.41.41.11.31.41.3-1.31.2-1.21.11.61.11.11.2
Condit. Reinf. active minus inactive responses1.31.62.31.4-1.41.41.4-1.4-0.80.5-0.81.31.31.31.31.41.41.3-0.50.51.5-1.51.41.31.31.51.4
Condit. Reinf. active-inactive response ratio2.93.03.81.9-1.91.91.9-1.9-1.31.1-1.31.81.81.71.71.91.81.7-1.11.31.9-1.91.91.61.91.91.9
Condit. Reinf. active responses0.00.00.0-0.00.00.0-0.00.0-0.2-0.1-0.20.0-0.10.0-0.0-0.00.0-0.10.1-0.10.1-0.1-0.0-0.0-0.10.0-0.0
Condit. Reinf. inactive responses1.62.02.7-1.61.6-1.6-1.61.60.6-0.70.6-1.5-1.5-1.5-1.5-1.6-1.5-1.50.7-0.9-1.61.6-1.6-1.5-1.6-1.6-1.6
Condit. Reinf. lever presses0.40.60.9-0.90.9-0.8-0.90.90.2-0.60.2-0.8-0.8-0.8-0.7-0.9-0.8-0.90.6-0.7-0.60.6-0.9-0.7-0.9-0.8-0.8
Condit. Reinf. lever reinforcers received0.00.00.1-0.20.2-0.2-0.20.2-0.3-0.0-0.3-0.2-0.3-0.2-0.2-0.2-0.2-0.30.1-0.1-0.10.1-0.2-0.2-0.3-0.1-0.2
Pavlov. Cond. lever latency0.30.40.60.7-0.70.60.7-0.7-0.40.6-0.40.60.60.50.50.70.60.6-0.60.70.4-0.40.70.50.70.60.7
Pavlov. Cond. magazine entry latency0.70.81.21.0-1.00.91.0-1.0-0.80.7-0.80.80.90.80.80.90.90.8-0.70.61.1-1.10.90.80.90.90.9
Pavlov. Cond. change in total contacts0.20.30.90.4-0.40.50.4-0.40.4-0.70.40.50.50.60.60.40.60.50.7-0.90.7-0.70.40.70.40.50.4
Pavlov. Cond. index score0.00.00.10.1-0.10.10.1-0.1-0.0-0.1-0.00.00.10.10.10.10.10.00.1-0.20.3-0.30.10.1-0.00.10.0
Pavlov. Cond. latency score0.10.10.30.3-0.30.30.3-0.30.0-0.10.00.20.30.30.30.30.30.20.2-0.30.5-0.50.20.40.20.30.2
Pavlov. Cond. lever contacts0.30.41.6-0.50.5-0.3-0.50.50.9-1.20.9-0.3-0.3-0.2-0.2-0.5-0.2-0.31.2-1.3-0.20.2-0.5-0.1-0.5-0.4-0.4
Pavlov. Cond. magazine entry number0.30.40.7-0.70.7-0.7-0.70.70.2-0.20.2-0.6-0.7-0.7-0.7-0.7-0.7-0.70.1-0.0-0.80.8-0.7-0.7-0.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.41.83.1-1.31.3-1.4-1.31.3-1.21.1-1.2-1.5-1.4-1.5-1.6-1.3-1.5-1.6-1.11.3-1.31.3-1.2-1.7-1.3-1.2-1.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.1-0.10.10.1-0.1-0.0-0.1-0.00.10.10.10.10.10.10.00.1-0.20.3-0.30.10.10.00.10.1
Pavlov. Cond. response bias0.10.10.4-0.30.3-0.2-0.30.30.3-0.50.3-0.2-0.3-0.2-0.2-0.3-0.2-0.30.5-0.6-0.10.1-0.3-0.1-0.4-0.3-0.3
Conditioned reinforcement - actives0.50.51.20.9-0.90.60.9-0.90.1-0.30.10.50.70.60.60.90.71.00.7-1.10.6-0.60.90.50.90.60.4
Conditioned reinforcement - inactives1.61.83.31.6-1.61.31.6-1.60.7-0.80.71.41.21.21.31.51.41.71.1-1.81.4-1.41.41.31.61.10.9
Conditioned locomotion0.10.10.40.4-0.40.00.4-0.4-0.40.6-0.4-0.30.20.00.00.30.10.2-0.2-0.20.2-0.20.3-0.10.20.1-0.0
Intermittent access intake day 1-15 change0.70.71.21.1-1.10.91.1-1.1-0.1-0.1-0.10.70.80.90.90.90.80.90.3-0.70.7-0.70.90.80.91.00.7
Intermittent access intake escalation0.30.30.80.8-0.80.50.8-0.8-0.90.6-0.90.30.50.50.50.60.40.4-0.30.20.4-0.40.60.30.60.70.4
Intermittent access intake escalation 20.80.84.90.4-0.4-0.00.4-0.4-2.21.9-2.2-0.3-0.1-0.1-0.10.1-0.1-0.3-1.61.7-0.00.00.2-0.40.00.30.0
Intermitt. access day 1 inactive lever presses0.30.31.10.4-0.40.40.4-0.4-1.11.0-1.10.40.30.30.30.30.30.3-1.00.60.6-0.60.30.10.30.50.3
Intermitt. access day 15 inactive lever presses2.32.53.91.8-1.81.91.8-1.8-0.30.5-0.31.91.81.81.91.81.81.8-0.20.01.4-1.41.71.81.72.01.8
Intermitt. access escalation Index3.12.85.3-1.61.6-1.9-1.61.60.3-0.60.3-1.7-1.9-1.9-2.0-1.8-1.9-1.70.6-0.4-2.32.3-2.0-2.0-1.7-2.0-1.9
Intermittent access day 1 total infusions0.40.50.9-0.60.6-0.8-0.60.60.7-0.30.7-0.6-0.8-0.8-0.7-0.5-0.6-0.40.5-1.0-1.01.0-0.5-0.6-0.7-0.9-0.9
Intermittent access day 15 total infusions0.10.11.1-0.00.0-0.3-0.00.00.4-0.20.4-0.3-0.2-0.2-0.2-0.0-0.20.00.6-1.0-0.50.5-0.1-0.2-0.1-0.3-0.4
Intermittent access terminal intake (last 3 days)0.10.10.80.5-0.50.20.5-0.50.3-0.20.30.20.20.20.20.40.20.40.5-0.90.0-0.00.30.20.30.10.1
Intermittent access total infusions0.10.11.4-0.00.0-0.1-0.00.00.5-0.40.5-0.2-0.1-0.1-0.10.1-0.00.10.7-1.2-0.20.20.0-0.1-0.1-0.2-0.3
Intermittent access day 1 locomotion0.20.21.2-0.10.1-0.5-0.10.1-0.51.1-0.5-0.4-0.5-0.5-0.6-0.1-0.4-0.0-0.90.4-0.40.4-0.1-0.6-0.0-0.6-0.5
Intermittent access day 15 total locomotion1.11.23.01.2-1.20.91.2-1.2-1.41.7-1.40.71.00.80.81.20.80.9-1.50.91.0-1.01.20.61.11.00.9
Intermittent access total locomotion0.80.92.91.0-1.00.71.0-1.0-1.31.7-1.30.50.70.60.61.00.70.8-1.40.70.9-0.90.90.50.80.70.7
Intermittent access standard deviation2.52.73.81.9-1.91.81.9-1.90.4-0.40.41.61.81.81.91.71.81.80.6-0.71.9-1.91.81.81.61.81.7
Cocaine induced anxiety2.52.94.3-1.81.8-1.8-1.81.8-1.21.1-1.2-1.9-1.9-1.9-1.9-1.7-1.9-2.0-1.11.6-1.51.5-1.6-2.1-1.7-1.6-1.7
Post-drug Anxiety1.01.11.8-1.31.3-1.1-1.31.3-0.80.7-0.8-1.2-1.1-1.1-1.1-1.2-1.1-1.4-0.70.9-0.70.7-1.2-1.3-1.2-0.9-1.0
Baseline Anxiety0.40.42.80.2-0.20.30.2-0.21.2-1.31.20.20.20.30.40.10.30.21.3-1.70.3-0.3-0.10.5-0.00.20.1
Lifetime Intake0.10.11.00.1-0.1-0.10.1-0.10.3-0.20.3-0.2-0.0-0.0-0.10.20.00.20.5-1.0-0.20.20.2-0.10.0-0.2-0.2
Incentive Sensitization - Responses0.70.71.1-1.01.0-0.9-1.01.00.6-0.40.6-0.8-0.9-0.9-0.9-0.9-0.9-0.80.8-1.0-0.80.8-0.9-0.8-0.7-0.9-0.9
Incentive Sensitization - Breakpoint0.90.91.2-1.11.1-1.0-1.11.10.5-0.40.5-0.9-1.0-1.0-1.0-1.0-1.0-1.00.7-1.0-0.80.8-1.0-0.9-0.9-1.0-1.0
Progressive ratio test 1 active lever presses0.20.20.6-0.30.3-0.5-0.30.30.3-0.50.3-0.2-0.4-0.4-0.5-0.1-0.30.00.6-0.7-0.80.8-0.1-0.4-0.2-0.6-0.6
Progressive ratio test 1 breakpoint0.20.20.8-0.20.2-0.4-0.20.20.4-0.60.4-0.2-0.4-0.4-0.4-0.1-0.30.00.7-0.8-0.90.9-0.1-0.4-0.3-0.6-0.6
Progressive ratio test 1 inactive lever presses0.40.43.50.0-0.0-0.00.0-0.01.2-1.21.2-0.0-0.10.00.10.00.10.31.4-1.9-0.00.00.10.2-0.1-0.1-0.3
Progressive ratio test 2 active lever presses0.80.92.2-1.01.0-0.9-1.01.00.8-0.80.8-0.8-0.8-0.9-0.8-0.7-0.8-0.61.2-1.5-1.11.1-0.6-0.8-0.7-1.0-1.1
Progressive ratio test 2 breakpoint1.31.53.5-1.31.3-1.2-1.31.31.0-1.01.0-1.1-1.1-1.1-1.1-1.0-1.1-0.91.4-1.9-1.41.4-0.9-1.0-1.1-1.3-1.4
Progressive ratio test 2 inactive lever presses0.30.40.80.8-0.80.60.8-0.8-0.40.6-0.40.70.60.60.60.90.70.8-0.3-0.40.4-0.40.90.50.70.60.4
Total sessions with >9 infusions0.10.10.40.3-0.30.20.3-0.3-0.00.1-0.00.20.30.20.10.40.30.60.2-0.60.0-0.00.50.10.50.00.0
Short access day 1 total inactive lever presses0.70.84.00.6-0.60.20.6-0.6-1.82.0-1.80.10.10.10.00.40.10.0-1.81.20.6-0.60.1-0.20.40.30.2
Short access day 10 total inactive lever presses0.10.10.80.2-0.20.00.2-0.2-0.90.8-0.9-0.1-0.1-0.00.0-0.1-0.0-0.1-0.70.40.2-0.2-0.1-0.30.00.20.0
Short access day 1 total infusions0.20.20.6-0.30.3-0.6-0.30.30.1-0.10.1-0.8-0.6-0.7-0.7-0.4-0.7-0.40.1-0.3-0.30.3-0.6-0.7-0.3-0.8-0.7
Short access day 10 total infusions0.10.10.50.3-0.30.30.3-0.30.10.00.10.10.40.30.30.50.40.60.4-0.60.0-0.00.70.30.40.20.2
Short access total infusions0.10.10.30.4-0.40.20.4-0.40.10.00.10.10.30.20.20.50.30.50.2-0.4-0.10.10.50.20.20.10.1
Short access day 1 locomotion3.23.44.8-2.12.1-2.1-2.12.10.3-0.20.3-2.2-2.0-2.1-2.1-1.9-2.1-2.00.3-0.4-1.91.9-1.8-2.0-2.2-2.2-2.1
Short access day 10 total locomotion0.60.63.50.3-0.30.10.3-0.3-1.71.9-1.7-0.20.10.00.00.20.10.0-1.81.40.1-0.10.3-0.1-0.00.20.2
Short access total locomotion0.20.20.7-0.20.2-0.4-0.20.2-0.60.8-0.6-0.5-0.3-0.4-0.5-0.2-0.4-0.3-0.70.5-0.50.5-0.1-0.5-0.5-0.5-0.4
Compulsive drug intake3.03.04.4-2.02.0-2.0-2.02.00.1-0.30.1-2.0-2.0-2.0-2.1-1.9-2.0-1.90.10.2-1.71.7-1.7-2.0-1.8-2.0-2.0
One hour access (0.3 mA shock)0.50.61.5-0.50.5-0.9-0.50.50.2-0.10.2-0.9-0.9-0.9-1.0-0.6-0.8-0.50.5-0.7-1.21.2-0.4-0.9-0.6-1.0-1.1
One hour access (shock baseline)0.60.71.41.1-1.10.81.1-1.1-0.70.7-0.70.80.80.80.81.10.91.0-0.2-0.10.5-0.51.20.70.90.70.7
Number of responses in last shaping day0.20.20.80.5-0.50.40.5-0.5-0.50.5-0.50.40.50.40.30.60.40.6-0.40.40.2-0.20.90.40.70.30.4
Context. condit. distance diff. score5.36.410.0-2.62.6-2.8-2.62.6-1.51.5-1.5-2.8-2.8-3.0-3.1-2.6-2.9-3.0-1.51.3-2.62.6-2.5-3.2-2.6-2.5-2.7
Locomotion velocity, session 10.20.20.5-0.40.4-0.4-0.40.4-0.60.6-0.6-0.4-0.4-0.5-0.5-0.3-0.5-0.5-0.70.5-0.40.4-0.3-0.6-0.3-0.3-0.4
Locomotion distance, session 10.50.71.6-0.80.8-0.6-0.80.81.3-1.21.3-0.5-0.6-0.5-0.5-0.7-0.6-0.51.1-1.1-0.90.9-0.7-0.4-0.8-0.8-0.7
Locomotion velocity, session 20.10.10.4-0.00.0-0.0-0.00.0-0.60.5-0.6-0.0-0.0-0.1-0.10.0-0.1-0.1-0.60.6-0.10.10.1-0.20.00.00.0
Locomotion distance, session 20.30.40.7-0.80.8-0.7-0.80.80.5-0.50.5-0.6-0.7-0.7-0.7-0.7-0.7-0.70.4-0.3-0.80.8-0.7-0.6-0.7-0.7-0.7
Locomotion velocity, session 30.20.21.00.1-0.10.20.1-0.10.8-1.00.80.20.20.30.30.10.20.30.9-0.90.0-0.00.10.30.10.10.1
Locomotion distance, session 31.61.72.4-1.41.4-1.4-1.41.40.7-0.80.7-1.5-1.4-1.4-1.4-1.4-1.4-1.40.8-0.8-1.51.5-1.5-1.3-1.3-1.5-1.5
Stereotopy head waving bouts, day 31.92.32.71.6-1.61.51.6-1.6-1.61.5-1.61.41.51.31.31.61.41.3-1.61.61.6-1.61.61.11.61.61.6
Stereotopy head waving duration, day 31.41.62.01.4-1.41.31.4-1.4-1.21.1-1.21.31.31.21.21.41.21.2-1.21.21.4-1.41.41.11.41.41.4
Locomotion velocity, session 74.14.55.8-2.42.4-2.4-2.42.40.4-0.30.4-2.4-2.4-2.4-2.4-2.3-2.4-2.40.3-0.5-2.42.4-2.4-2.3-2.4-2.4-2.4
Locomotion distance, session 74.05.16.5-2.52.5-2.5-2.52.51.2-1.21.2-2.4-2.5-2.4-2.4-2.5-2.4-2.41.3-1.3-2.62.6-2.5-2.3-2.4-2.5-2.5
Stereotopy head waving bouts, day 71.92.22.91.7-1.71.71.7-1.7-0.50.5-0.51.61.61.61.61.71.61.6-0.60.61.6-1.61.61.61.61.71.7
Stereotopy head waving duration, day 72.73.34.32.0-2.02.02.0-2.0-0.90.9-0.91.92.01.91.92.11.91.9-0.91.02.0-2.02.01.92.02.02.0
Locomotion velocity, session 81.41.78.10.1-0.1-0.20.1-0.1-2.82.8-2.8-0.2-0.1-0.4-0.50.1-0.3-0.5-2.82.8-0.00.00.2-0.80.00.20.1
Locomotion distance, session 82.84.26.4-2.12.1-2.3-2.12.1-1.01.0-1.0-2.3-2.2-2.4-2.5-2.1-2.4-2.5-1.01.0-2.22.2-2.1-2.5-2.1-2.1-2.2
Degree of sensitization distance0.40.40.6-0.50.5-0.6-0.50.5-0.70.8-0.7-0.6-0.6-0.7-0.7-0.5-0.6-0.7-0.70.7-0.50.5-0.4-0.8-0.5-0.5-0.5
Degree of sensitization stereotypy1.21.31.81.3-1.31.31.3-1.3-0.30.4-0.31.31.31.31.31.31.31.3-0.30.41.3-1.31.31.31.31.31.3
Condit. Reinf. active minus inactive responses0.70.81.3-1.01.0-1.1-1.01.00.00.00.0-1.0-1.0-1.0-1.1-1.0-1.0-1.00.0-0.0-1.11.1-0.9-1.0-1.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.00.00.0-0.00.00.5-0.50.50.10.00.10.10.00.10.10.5-0.5-0.20.20.00.20.1-0.00.0
Condit. Reinf. active responses1.21.41.9-1.31.3-1.4-1.31.30.4-0.30.4-1.3-1.4-1.3-1.4-1.3-1.3-1.30.4-0.3-1.41.4-1.3-1.3-1.4-1.4-1.3
Condit. Reinf. inactive responses2.12.53.4-1.71.7-1.7-1.71.71.2-1.21.2-1.6-1.7-1.6-1.5-1.7-1.6-1.61.2-1.2-1.61.6-1.7-1.4-1.9-1.7-1.7
Incentive salience index mean1.41.72.5-1.31.3-1.4-1.31.3-1.01.0-1.0-1.5-1.4-1.5-1.6-1.3-1.5-1.5-1.01.0-1.31.3-1.2-1.6-1.3-1.3-1.3
Condit. Reinf. lever presses2.33.14.7-1.71.7-2.0-1.71.7-1.41.4-1.4-2.0-2.0-2.1-2.1-1.7-2.0-2.1-1.41.4-1.71.7-1.7-2.2-1.8-1.7-1.8
Time in familiar zone, hab. session 14.03.75.3-2.02.0-1.8-2.02.02.2-2.22.2-1.7-1.8-1.6-1.6-2.0-1.7-1.62.3-2.3-1.91.9-2.0-1.4-2.0-2.0-2.0
Time in novel zone, hab. session 12.22.14.11.4-1.41.21.4-1.4-1.92.0-1.91.11.21.01.01.41.11.1-2.02.01.3-1.31.40.91.41.41.4
Total zone transitions, hab. session 10.60.81.1-1.01.0-1.0-1.01.00.5-0.60.5-0.9-1.0-1.0-1.0-1.0-1.0-1.00.5-0.4-1.01.0-1.0-0.9-1.1-1.0-1.0
Total locomotion distance, hab. session 10.50.81.1-0.90.9-0.9-0.90.90.7-0.70.7-0.9-0.9-0.9-0.9-1.0-0.9-0.80.6-0.6-1.11.1-1.0-0.8-0.9-0.9-0.9
Locomotion velocity, hab. session 10.30.40.8-0.60.6-0.6-0.60.60.8-0.90.8-0.5-0.6-0.5-0.5-0.6-0.5-0.50.8-0.7-0.70.7-0.7-0.4-0.6-0.6-0.6
Time in familiar zone, hab. session 20.30.40.7-0.60.6-0.5-0.60.60.8-0.80.8-0.5-0.5-0.4-0.4-0.6-0.5-0.50.7-0.6-0.50.5-0.7-0.3-0.7-0.6-0.5
Time in novel zone, hab. session 20.30.30.50.6-0.60.60.6-0.6-0.40.4-0.40.60.60.60.60.60.60.6-0.70.50.5-0.50.70.60.70.60.6
Total zone transitions, hab. session 20.10.10.4-0.10.1-0.0-0.10.10.6-0.70.60.0-0.00.00.0-0.10.00.00.4-0.4-0.20.2-0.10.1-0.2-0.1-0.1
Total locomotion distance, hab. session 21.11.52.2-1.31.3-1.3-1.31.30.9-0.90.9-1.3-1.3-1.2-1.2-1.4-1.2-1.20.7-0.7-1.51.5-1.4-1.1-1.3-1.3-1.3
Locomotion velocity, hab. session 21.21.62.4-1.41.4-1.4-1.41.40.9-0.90.9-1.3-1.3-1.3-1.3-1.4-1.3-1.20.7-0.6-1.51.5-1.4-1.2-1.3-1.4-1.4
Novel to familiar place preference ratio0.10.10.30.0-0.00.10.0-0.00.6-0.60.60.10.10.10.10.00.10.10.4-0.5-0.10.10.00.20.00.00.0
Novelty place preference0.10.10.10.3-0.30.30.3-0.30.3-0.40.30.30.30.30.30.30.30.40.2-0.30.2-0.20.30.40.30.30.3
Time in novel zone, NPP test0.20.20.30.4-0.40.50.4-0.40.2-0.20.20.50.50.50.50.40.50.50.1-0.10.3-0.30.40.50.50.40.5
Total zone transitions, NPP test1.11.62.4-1.41.4-1.4-1.41.40.5-0.40.5-1.4-1.4-1.4-1.4-1.4-1.4-1.40.4-0.4-1.51.5-1.4-1.3-1.4-1.4-1.4
Total locomotion distance, NPP test1.21.72.5-1.41.4-1.4-1.41.41.1-1.11.1-1.3-1.3-1.2-1.2-1.4-1.3-1.21.0-1.0-1.61.6-1.4-1.2-1.3-1.4-1.4
Locomotion velocity, NPP test2.13.04.3-1.81.8-1.8-1.81.81.4-1.41.4-1.8-1.8-1.7-1.7-1.9-1.7-1.61.3-1.3-2.12.1-1.9-1.6-1.7-1.9-1.8
Pavlov. Cond. lever latency1.31.64.90.6-0.61.00.6-0.62.1-2.22.11.01.01.21.20.71.11.22.2-2.20.7-0.70.71.30.80.70.8
Pavlov. Cond. magazine entry latency1.41.84.6-0.80.8-1.1-0.80.8-2.12.1-2.1-1.2-1.1-1.3-1.4-0.9-1.2-1.4-2.02.1-0.90.9-0.9-1.5-1.1-0.9-0.9
Pavlov. Cond. change in total contacts1.11.24.10.8-0.80.60.8-0.8-2.02.0-2.00.60.60.50.40.80.50.4-1.92.00.8-0.80.90.30.60.80.8
Pavlov. Cond. index score1.72.26.2-0.80.8-1.2-0.80.8-2.42.4-2.4-1.3-1.2-1.4-1.5-0.9-1.3-1.4-2.42.5-0.80.8-0.8-1.6-1.0-0.9-1.0
Pavlov. Cond. latency score1.41.86.4-0.50.5-0.9-0.50.5-2.52.5-2.5-0.9-0.9-1.1-1.1-0.6-0.9-1.1-2.42.5-0.50.5-0.5-1.3-0.7-0.6-0.6
Pavlov. Cond. lever contacts1.11.35.6-0.20.2-0.5-0.20.2-2.22.4-2.2-0.6-0.5-0.7-0.7-0.2-0.6-0.7-2.32.4-0.20.2-0.2-0.9-0.3-0.2-0.3
Pavlov. Cond. magazine entry number1.72.13.31.3-1.31.51.3-1.31.5-1.41.51.51.51.61.71.31.61.71.4-1.51.3-1.31.31.81.51.31.4
Pavlov. Cond. intertrial magazine entries0.91.13.7-0.90.9-0.6-0.90.91.9-1.71.9-0.5-0.6-0.4-0.4-0.8-0.5-0.41.8-1.9-0.80.8-0.8-0.2-0.7-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.1.82.35.8-0.90.9-1.3-0.90.9-2.32.3-2.3-1.4-1.3-1.5-1.6-1.0-1.4-1.6-2.22.4-1.01.0-1.0-1.7-1.2-1.0-1.1
Pavlov. Cond. response bias1.92.35.0-1.11.1-1.4-1.11.1-2.12.2-2.1-1.5-1.4-1.6-1.6-1.1-1.5-1.6-2.12.2-1.11.1-1.1-1.8-1.3-1.1-1.2
Bone: apparent density1.62.63.3-1.71.7-1.6-1.71.71.8-1.51.8-1.5-1.6-1.5-1.4-1.7-1.5-1.41.5-1.7-1.71.7-1.6-1.3-1.7-1.7-1.7
Bone surface0.10.20.60.5-0.50.40.5-0.5-0.50.8-0.50.50.40.40.40.50.40.4-0.70.50.5-0.50.60.30.50.50.5
Bone volume0.10.10.20.3-0.30.30.3-0.30.5-0.20.50.40.30.30.40.30.30.30.3-0.50.3-0.30.30.40.30.30.2
Bone: connectivity density2.64.15.3-2.22.2-2.2-2.22.21.1-0.71.1-2.1-2.2-2.2-2.2-2.2-2.2-2.20.7-0.8-2.32.3-2.2-2.1-2.2-2.2-2.2
Bone: cortical apparent density0.70.92.40.6-0.60.80.6-0.61.5-1.41.50.90.70.91.00.60.91.01.3-1.60.5-0.50.61.20.60.50.6
Bone: cortical area2.23.44.32.0-2.02.02.0-2.0-0.80.7-0.82.02.02.02.02.12.02.0-0.60.62.0-2.02.12.02.02.02.1
Bone: cortical porosity0.50.60.90.8-0.80.80.8-0.80.6-0.50.60.80.80.80.90.70.90.90.4-0.40.7-0.70.70.90.70.70.8
Bone: cortical porosity0.70.70.91.0-1.00.91.0-1.0-0.50.5-0.50.90.90.90.90.90.90.9-0.60.61.0-1.01.00.80.91.00.9
Bone: cortical thickness3.05.08.02.2-2.22.52.2-2.21.6-1.61.62.62.52.62.72.22.62.71.6-1.72.1-2.12.22.82.22.12.3
Bone: cortical thickness1.11.33.60.6-0.60.90.6-0.61.9-1.81.91.00.91.01.10.71.01.11.8-1.90.5-0.50.71.20.70.60.7
Bone: cortical tissue density0.50.71.90.5-0.50.70.5-0.51.4-1.21.40.80.70.80.80.60.80.91.2-1.40.4-0.40.61.00.50.50.6
Bone: elastic displacement0.20.20.70.2-0.20.30.2-0.20.8-0.70.80.30.30.40.40.20.40.40.7-0.70.1-0.10.10.40.20.20.3
Bone: elastic work1.72.23.11.7-1.71.71.7-1.70.10.10.11.71.71.71.81.71.71.8-0.0-0.01.6-1.61.61.71.71.61.7
Bone: endosteal estimation3.26.917.62.3-2.32.02.3-2.3-4.24.0-4.21.72.01.71.62.31.81.6-3.94.02.4-2.42.41.22.42.42.2
Bone: endosteal perimeter1.32.613.00.4-0.40.10.4-0.4-3.63.4-3.6-0.10.1-0.2-0.30.4-0.1-0.3-3.33.40.6-0.60.5-0.60.50.50.4
Bone: final force5.69.212.93.3-3.33.53.3-3.30.2-0.40.23.63.53.53.63.43.53.50.4-0.33.3-3.33.43.63.33.33.4
Bone: final moment5.18.411.63.1-3.13.33.1-3.10.1-0.20.13.43.43.43.43.23.33.40.2-0.23.2-3.23.33.43.23.23.3
Bone: marrow area3.26.817.12.3-2.32.02.3-2.3-4.13.9-4.11.72.01.71.62.31.81.6-3.83.92.4-2.42.41.22.32.42.2
Bone: maximum diameter1.22.27.21.1-1.10.81.1-1.1-2.72.7-2.70.70.80.60.61.10.70.6-2.62.61.1-1.11.10.41.11.11.0
Bone: maximum force4.88.411.23.2-3.23.33.2-3.2-0.20.0-0.23.33.33.33.43.33.33.3-0.00.13.2-3.23.33.33.23.23.2
Bone: maximum moment4.47.710.23.1-3.13.23.1-3.1-0.30.2-0.33.23.23.23.23.23.23.2-0.30.23.0-3.03.23.13.13.13.1
Bone: minimum diameter1.42.58.91.1-1.10.91.1-1.1-3.02.8-3.00.70.90.70.61.20.80.6-2.72.91.2-1.21.20.41.21.21.1
Bone: periosteal estimation3.26.68.92.6-2.62.52.6-2.6-3.02.8-3.02.32.42.32.22.72.32.2-2.72.72.7-2.72.71.92.72.72.6
Bone: periosteal perimeter1.62.76.31.5-1.51.31.5-1.5-2.52.3-2.51.21.31.21.11.51.21.1-2.32.21.6-1.61.60.91.51.61.5
Bone: post-yield work0.50.63.50.1-0.1-0.10.1-0.1-1.81.6-1.8-0.2-0.1-0.3-0.30.1-0.2-0.3-1.61.90.1-0.10.1-0.50.00.10.0
Bone: stiffness1.21.92.71.4-1.41.51.4-1.40.5-0.70.51.61.51.61.61.51.61.60.7-0.61.5-1.51.51.61.41.41.4
Bone: tissue strength4.14.05.42.2-2.22.32.2-2.20.20.00.22.32.32.32.32.32.32.3-0.1-0.12.2-2.22.22.32.22.22.2
Bone: trabecular number1.72.73.8-1.71.7-1.6-1.71.71.9-1.61.9-1.4-1.5-1.4-1.4-1.6-1.5-1.41.6-1.8-1.81.8-1.6-1.3-1.7-1.7-1.7
Bone: trabecular spacing4.15.36.72.6-2.62.42.6-2.6-1.71.4-1.72.22.42.32.32.52.42.3-1.41.62.6-2.62.62.22.52.52.5
Bone: trabecular thickness1.31.61.8-1.41.4-1.2-1.41.41.3-1.21.3-1.1-1.2-1.1-1.1-1.3-1.2-1.21.2-1.2-1.31.3-1.4-1.1-1.3-1.3-1.3
Bone: trabecular tissue density1.72.43.31.6-1.61.81.6-1.6-0.20.2-0.21.71.71.81.81.71.81.7-0.20.11.8-1.81.71.81.71.81.8
Breakpoint value in progressive ratio session1.11.22.1-1.31.3-1.2-1.31.30.3-0.50.3-1.1-1.2-1.2-1.2-1.1-1.2-1.00.6-0.2-1.41.4-1.2-1.2-1.2-1.2-1.1
Distance traveled before self-admin0.20.21.00.1-0.1-0.10.1-0.1-1.00.9-1.0-0.2-0.1-0.2-0.30.0-0.2-0.1-0.80.9-0.30.3-0.0-0.30.00.1-0.1
Distance traveled after self-admin0.50.52.40.1-0.10.50.1-0.1-1.11.3-1.10.40.40.40.40.30.40.2-1.41.50.8-0.80.40.40.30.70.7
Delta time in closed arm before/after self-admin0.20.20.50.4-0.40.40.4-0.4-0.00.6-0.00.30.40.40.50.40.40.3-0.40.70.3-0.30.20.60.30.40.5
Delta time in open arm before/after self-admin0.00.00.10.1-0.10.10.1-0.10.1-0.30.10.30.00.10.20.00.20.1-0.0-0.30.1-0.10.20.2-0.10.20.1
Diff in mean of infusions in LGA sessions3.64.05.2-1.81.8-2.2-1.81.81.5-1.81.5-2.1-2.2-2.1-2.1-2.1-2.2-2.01.8-1.3-2.32.3-2.2-2.0-2.0-2.1-2.2
Extinction: sum of active levers before priming0.50.50.7-0.50.5-0.7-0.50.50.7-0.70.7-0.6-0.7-0.7-0.7-0.6-0.6-0.60.8-0.3-0.90.9-0.7-0.6-0.8-0.8-0.8
Active lever presses in extinction session 60.30.32.0-0.40.4-0.1-0.40.40.9-0.90.9-0.1-0.2-0.1-0.0-0.3-0.1-0.21.4-1.0-0.40.4-0.5-0.0-0.4-0.2-0.1
Delta distance traveled before/after self-admin1.11.12.11.0-1.01.21.0-1.0-0.30.6-0.31.21.11.21.21.01.21.0-0.70.51.4-1.41.21.31.01.31.3
Delta ambulatory time before/after self-admin0.50.61.20.6-0.60.70.6-0.6-0.80.9-0.80.60.50.70.70.50.70.6-1.10.91.0-1.00.70.60.60.80.8
Time in closed arm before self-admin0.00.00.1-0.40.4-0.1-0.40.40.2-0.30.2-0.0-0.0-0.1-0.1-0.3-0.2-0.2-0.1-0.10.2-0.2-0.3-0.1-0.2-0.1-0.1
Time in closed arm after self-admin0.70.71.50.9-0.91.00.9-0.90.7-0.50.70.91.01.01.00.80.90.90.10.00.9-0.90.61.20.80.80.9
Time in open arm before self-admin0.30.30.90.1-0.1-0.50.1-0.1-0.90.8-0.9-0.6-0.6-0.6-0.6-0.1-0.4-0.2-0.71.0-0.50.5-0.1-0.7-0.1-0.4-0.4
Time in open arm after self-admin0.50.51.3-0.50.5-0.9-0.50.5-0.70.4-0.7-0.8-1.1-1.0-1.0-0.7-0.8-0.7-0.30.2-0.70.7-0.5-1.0-0.9-0.8-0.9
Sum of active levers in priming session hrs 5-60.40.40.8-0.30.3-0.7-0.30.30.6-0.50.6-0.6-0.7-0.7-0.7-0.6-0.8-0.70.3-0.3-0.90.9-0.9-0.7-0.8-0.8-0.6
Time to tail flick, vehicle, before self-admin0.20.20.6-0.30.3-0.4-0.30.3-0.70.8-0.7-0.3-0.3-0.4-0.4-0.2-0.4-0.4-0.70.7-0.20.2-0.3-0.5-0.2-0.3-0.4
Time to tail flick, vehicle, after self-admin0.90.91.7-0.90.9-0.9-0.90.9-1.21.3-1.2-1.2-1.0-1.0-1.0-0.8-1.0-1.2-0.81.2-0.50.5-0.8-1.2-0.8-0.7-0.9
Time to tail flick, test, before self-admin0.30.31.90.2-0.20.20.2-0.20.8-1.10.80.30.20.20.20.20.30.21.0-1.4-0.00.00.40.30.20.20.0
Time to tail flick, test, after self-admin0.91.01.4-0.70.7-1.1-0.70.7-1.10.9-1.1-1.2-1.1-1.1-1.2-0.9-1.1-1.1-0.81.1-1.11.1-0.9-1.2-0.7-1.0-0.9
Delta time to tail flick, vehicle, before/after SA0.60.61.3-1.01.0-0.9-1.01.00.20.00.2-1.1-0.9-0.9-0.9-0.9-0.9-1.00.20.4-0.50.5-0.9-0.9-0.9-0.8-0.8
Delta time to tail flick, test, before/after SA1.00.91.7-0.90.9-1.1-0.90.9-0.30.4-0.3-1.2-1.0-1.0-1.1-1.1-1.2-1.1-0.30.7-1.01.0-1.3-1.0-0.9-1.0-0.9
Ambulatory time before self-admin0.00.00.20.4-0.40.10.4-0.4-0.40.2-0.40.20.00.10.00.20.10.2-0.1-0.00.0-0.00.1-0.00.20.20.0
Ambulatory time after self-admin0.30.41.50.2-0.20.30.2-0.2-1.11.1-1.10.30.20.30.20.20.30.1-1.21.20.5-0.50.30.20.20.50.5
Total heroin consumption0.00.00.10.4-0.4-0.10.4-0.4-0.0-0.0-0.00.1-0.2-0.1-0.20.0-0.10.00.3-0.10.1-0.1-0.1-0.2-0.1-0.1-0.1
Area under the delay curve2.02.23.31.6-1.61.71.6-1.60.1-0.50.11.61.61.61.71.61.61.80.4-0.31.6-1.61.71.71.81.51.6
Delay disc. indifference point, 0s delay0.40.50.90.7-0.70.70.7-0.7-0.70.4-0.70.70.70.60.60.70.60.7-0.70.60.6-0.60.80.51.00.60.7
Delay disc. indifference point, 16s delay2.02.04.01.3-1.31.31.3-1.31.6-2.01.61.31.21.41.51.21.41.62.0-1.71.1-1.11.31.71.21.01.2
Delay disc. indifference point, 2s delay2.02.33.81.7-1.71.61.7-1.7-0.90.9-0.91.61.61.51.51.71.51.7-1.20.91.4-1.41.81.52.01.61.6
Delay disc. indifference point, 24s delay0.50.50.90.7-0.70.80.7-0.70.5-0.60.50.70.70.80.80.70.81.00.8-0.60.7-0.70.80.90.70.60.7
Delay disc. indifference point, 4s delay3.03.25.12.0-2.01.92.0-2.0-1.20.8-1.21.91.81.81.82.01.82.0-0.60.72.1-2.12.01.72.31.91.9
Delay disc. indifference point, 8s delay0.40.40.60.7-0.70.70.7-0.70.1-0.20.10.70.60.70.70.70.70.70.2-0.10.7-0.70.70.70.70.60.7
Delay discount exponential model param1.92.13.2-1.61.6-1.6-1.61.6-0.20.5-0.2-1.5-1.5-1.6-1.6-1.6-1.6-1.8-0.50.4-1.61.6-1.7-1.7-1.8-1.4-1.5
Delay discount hyperbolic model param2.02.13.4-1.61.6-1.7-1.61.60.10.20.1-1.6-1.6-1.6-1.6-1.7-1.6-1.8-0.20.2-1.61.6-1.7-1.6-1.8-1.5-1.6
Fecal boli incidents, locomotor time 10.80.91.4-1.11.1-1.0-1.11.10.3-0.10.3-1.0-1.0-1.0-1.0-1.1-1.0-1.1-0.20.1-1.01.0-1.2-1.0-1.0-1.1-1.1
Change in fecal boli incidents, locomotor task0.70.71.10.9-0.90.80.9-0.9-0.50.5-0.50.80.80.80.80.80.70.6-0.70.91.1-1.10.90.80.60.91.0
Time >=10cm from walls, locomotor time 10.80.82.20.7-0.70.70.7-0.7-1.51.4-1.50.30.60.50.60.70.60.4-1.41.31.3-1.30.90.40.40.80.5
Bouts of movement, locomotor time 11.11.21.9-1.21.2-1.2-1.21.2-0.80.7-0.8-1.2-1.2-1.2-1.3-1.2-1.2-1.3-0.40.4-1.01.0-1.2-1.4-1.2-1.1-1.2
Total resting periods, locomotor time 10.60.71.0-0.80.8-0.8-0.80.8-1.00.9-1.0-0.8-0.9-0.8-0.9-0.8-0.8-1.0-0.81.0-0.60.6-0.9-1.0-0.9-0.7-0.7
Rest time, locomotor task time 10.70.74.4-0.20.2-0.1-0.20.2-1.61.8-1.6-0.2-0.2-0.1-0.2-0.1-0.1-0.5-1.92.10.3-0.3-0.4-0.2-0.20.20.2
Distance moved, locomotor task time 10.70.71.20.9-0.90.80.9-0.90.7-0.70.71.00.90.90.90.80.91.10.9-0.90.5-0.51.10.91.00.70.8
Vertical activity count, locomotor time 10.40.41.10.7-0.70.50.7-0.70.6-1.00.60.60.70.60.60.60.60.81.1-0.90.1-0.10.60.60.80.40.5
Time >=10cm from walls, locomotor time 20.30.31.70.2-0.20.00.2-0.2-0.90.9-0.9-0.20.1-0.0-0.00.2-0.00.2-1.31.10.4-0.40.5-0.20.3-0.0-0.0
Bouts of movement, locomotor time 21.21.34.01.0-1.00.71.0-1.0-2.01.9-2.00.50.70.60.50.90.50.7-1.81.90.9-0.90.90.21.10.70.7
Total resting periods, locomotor time 21.21.35.40.7-0.70.40.7-0.7-2.32.2-2.30.20.40.30.20.70.30.4-2.02.20.7-0.70.7-0.10.90.50.5
Rest time, locomotor task time 21.51.77.5-0.20.2-0.5-0.20.2-2.72.7-2.7-0.7-0.6-0.6-0.7-0.3-0.6-0.9-2.72.60.3-0.3-0.6-0.8-0.4-0.2-0.2
Distance moved, locomotor task time 20.91.02.80.7-0.70.70.7-0.71.7-1.71.70.90.90.90.90.70.91.11.6-1.30.1-0.10.91.11.00.60.7
Vertical activity count, locomotor time 20.30.31.80.0-0.00.10.0-0.01.2-1.31.20.10.20.20.20.00.20.31.2-1.0-0.40.4-0.00.30.10.00.1
Weight adjusted by age3.33.65.12.1-2.12.12.1-2.1-1.41.4-1.42.32.12.01.92.22.01.8-1.31.22.0-2.01.91.72.02.02.2
Seeking ratio, delayed vs. immediate footshock0.40.50.90.8-0.80.80.8-0.8-0.30.3-0.30.80.80.70.80.90.80.8-0.40.20.6-0.60.90.70.60.70.8
Locomotion in novel chamber0.70.91.51.0-1.01.11.0-1.0-0.40.3-0.41.11.01.00.90.91.01.0-0.30.41.2-1.20.90.91.11.01.1
Locomotion in novel chamber post-restriction0.50.61.00.7-0.70.90.7-0.70.3-0.30.30.90.90.91.00.80.91.00.2-0.10.9-0.91.01.00.91.01.0
Progressive ratio4.55.38.02.5-2.52.62.5-2.5-0.20.2-0.22.52.72.62.62.62.62.7-0.30.32.4-2.42.72.62.82.52.5
Food seeking constrained by brief footshock0.00.00.10.1-0.1-0.20.1-0.10.00.10.0-0.1-0.2-0.1-0.1-0.0-0.00.10.00.1-0.30.30.0-0.10.1-0.2-0.2
Seeking ratio, punishment vs. effort4.04.96.9-2.42.4-2.5-2.42.40.3-0.20.3-2.4-2.6-2.5-2.5-2.5-2.5-2.60.3-0.2-2.52.5-2.6-2.5-2.6-2.4-2.5
Run reversals in cocaine runway, females0.30.31.60.1-0.10.30.1-0.11.3-1.21.30.30.30.40.40.10.40.40.8-0.90.3-0.30.20.5-0.00.00.3
Run reversals in cocaine runway, males1.91.86.41.2-1.20.71.2-1.2-2.42.5-2.40.60.60.50.41.00.60.7-2.52.41.0-1.01.10.11.00.70.8
Latency to leave start box in cocaine runway0.10.10.20.5-0.50.30.5-0.5-0.1-0.1-0.10.30.10.20.10.30.20.2-0.10.10.3-0.30.00.30.20.30.3
Latency to leave start box in cocaine runway, F0.20.20.4-0.30.3-0.5-0.30.3-0.10.2-0.1-0.5-0.6-0.6-0.6-0.3-0.6-0.5-0.40.3-0.70.7-0.5-0.5-0.4-0.4-0.5
Latency to leave start box in cocaine runway, M1.41.32.11.3-1.31.41.3-1.30.2-0.50.21.41.21.41.41.11.31.10.6-0.41.4-1.40.81.30.91.31.3
Cd content in liver0.50.60.90.6-0.60.80.6-0.60.9-0.80.90.90.80.80.90.70.80.80.8-0.80.6-0.60.60.90.60.60.7
Co content in liver1.41.72.51.2-1.21.31.2-1.21.2-1.31.21.51.41.41.51.21.41.41.4-1.41.2-1.21.21.61.21.11.2
Cu content in liver3.94.76.4-2.22.2-2.0-2.22.22.4-2.52.4-1.8-2.0-1.9-1.8-2.2-1.9-1.82.5-2.5-2.22.2-2.2-1.6-2.2-2.2-2.2
Fe content in liver0.50.50.80.6-0.60.70.6-0.60.9-0.90.90.70.80.80.80.60.80.80.9-0.90.6-0.60.60.80.60.60.6
K content in liver0.10.10.2-0.40.4-0.4-0.40.40.1-0.10.1-0.4-0.4-0.4-0.4-0.4-0.4-0.40.2-0.2-0.30.3-0.3-0.3-0.4-0.4-0.4
Mg content in liver2.22.23.3-1.51.5-1.6-1.51.5-1.21.2-1.2-1.6-1.6-1.7-1.8-1.5-1.7-1.7-1.21.2-1.51.5-1.4-1.8-1.5-1.5-1.5
Mn content in liver2.22.68.0-0.80.8-1.2-0.80.8-2.82.8-2.8-1.2-1.1-1.3-1.4-0.9-1.3-1.4-2.82.8-0.90.9-0.8-1.7-0.8-0.8-0.9
Na content in liver0.10.10.30.2-0.20.30.2-0.20.5-0.50.50.30.30.30.30.20.30.30.5-0.40.1-0.10.20.40.20.20.2
Rb content in liver0.91.11.5-1.21.2-1.2-1.21.20.4-0.50.4-1.2-1.2-1.2-1.1-1.2-1.2-1.20.6-0.6-1.01.0-1.2-1.1-1.2-1.2-1.2
Se content in liver1.62.06.0-0.80.8-1.0-0.80.8-2.42.5-2.4-1.1-1.0-1.2-1.3-0.8-1.1-1.3-2.32.3-0.80.8-0.8-1.5-0.8-0.8-0.9
Sr content in liver0.80.71.60.8-0.80.70.8-0.8-1.21.2-1.20.70.70.70.60.80.70.7-1.21.20.6-0.60.80.50.80.80.7
Zn content in liver0.00.00.10.0-0.0-0.10.0-0.0-0.30.2-0.3-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.20.2-0.20.2-0.0-0.20.0-0.1-0.1