Plekho2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000029242 0.03 0.03 3.1e-03 0.02 0.02 0.02 0.02 4.2e-03 5.6e-03 3.8e-03 4.9e-03
2 BLA mRNA stability ENSRNOG00000029242 0.06 0.06 7.6e-03 0.03 0.02 0.02 0.02 1.5e-02 2.6e-02 3.5e-02 2.7e-02
3 Brain mRNA stability ENSRNOG00000029242 0.33 0.15 1.8e-05 0.04 0.06 0.06 0.04 5.7e-05 1.5e-06 7.4e-06 1.3e-04
4 Liver intron excision ratio chr8:66099292:66105127 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.02 4.0e-03 5.7e-03 4.4e-03 5.2e-03
5 Liver intron excision ratio chr8:66112783:66154635 0.06 0.06 3.2e-06 0.04 0.04 0.04 0.04 1.6e-05 2.4e-05 1.7e-05 3.2e-05
6 Liver mRNA stability ENSRNOG00000029242 0.04 0.04 5.3e-04 0.02 0.02 0.02 0.02 1.7e-03 2.8e-03 2.1e-03 2.4e-03
7 PL mRNA stability ENSRNOG00000029242 0.08 0.07 2.4e-03 0.02 0.03 0.05 0.02 5.7e-03 1.7e-03 1.5e-04 7.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.51.52.41.2-1.4-0.3-1.21.5-1.5-0.9
BMI without tail0.20.41.7-0.3-0.3-1.30.30.4-0.4-0.5
Body weight0.00.10.1-0.0-0.2-0.30.00.3-0.4-0.1
Epididymis fat weight1.22.83.61.6-1.7-1.2-1.61.9-1.9-1.7
Glucose0.50.70.9-0.60.90.90.6-0.90.90.8
Heart weight0.20.30.6-0.50.60.50.5-0.50.50.8
Left kidney weight0.20.61.4-0.30.71.20.3-0.70.71.0
Right kidney weight0.20.61.4-0.30.91.20.3-0.80.81.0
Tail length0.72.02.9-1.71.60.11.7-1.61.60.8
Length with tail0.41.42.1-1.41.30.11.4-1.31.20.9
Length without tail0.20.40.60.7-0.7-0.2-0.70.7-0.8-0.3
Liver weight, left0.30.50.7-0.90.80.00.9-0.70.70.7
Liver weight, right1.72.84.0-1.42.01.31.4-1.91.91.5
Parametrial fat weight1.53.03.51.8-1.9-0.8-1.81.9-1.9-1.9
Retroperitoneal fat weight0.00.00.1-0.2-0.2-0.20.20.0-0.00.4
Intraocular pressure0.10.20.40.3-0.30.2-0.30.6-0.6-0.6
Extensor digitorum longus weight4.015.918.3-4.34.22.44.3-4.24.14.2
Soleus weight0.10.20.7-0.10.30.90.1-0.30.30.6
Tibialis anterior weight0.51.82.5-1.21.61.41.2-1.31.21.4
Tibia length0.10.30.5-0.40.60.60.4-0.50.50.7
Number of licking bursts0.20.20.4-0.60.3-0.40.6-0.20.20.5
Food consumed during 24 hour testing period3.64.46.4-2.32.51.22.3-2.12.11.9
Times rat made contact with spout0.10.10.6-0.20.1-0.80.20.1-0.1-0.0
Mean time between licks in bursts1.01.43.1-0.71.31.80.7-1.21.21.2
Mean num. licks in bursts0.00.00.10.3-0.10.0-0.30.2-0.2-0.3
Std. dev. time between licks in bursts1.51.83.4-0.91.41.90.9-1.41.41.6
Water consumed over 24 hours1.11.31.8-1.41.20.31.4-1.21.21.0
Indifference point 0 sec1.21.92.81.4-1.4-1.2-1.41.3-1.3-1.7
Indifference point AUC0.20.20.50.5-0.3-0.2-0.50.5-0.5-0.7
Indifference point function ln k0.50.71.1-0.90.60.60.9-1.01.01.0
Indifference point function log k0.50.71.1-0.90.60.60.9-1.01.01.0
Delay discounting total patch changes 0 sec1.01.62.51.2-1.3-1.1-1.21.1-1.1-1.6
Delay discounting total patch changes 12 sec0.40.50.80.9-0.6-0.2-0.90.7-0.7-0.8
Delay discounting total patch changes 18 sec1.31.72.91.3-1.1-1.3-1.31.2-1.2-1.7
Delay discounting total patch changes 24 sec2.73.44.82.2-1.7-0.6-2.21.8-1.8-2.0
Delay discounting total patch changes 6 sec0.20.30.80.4-0.4-0.9-0.40.4-0.4-0.8
Delay discounting time to switch 0 sec0.20.30.50.6-0.6-0.4-0.60.7-0.7-0.3
Delay discounting water rate 0 sec0.10.20.3-0.40.50.40.4-0.60.60.1
Delay discounting water rate 12 sec5.07.69.7-3.02.81.13.0-3.13.12.5
Delay discounting water rate 18 sec0.60.81.4-0.71.01.20.7-1.01.00.7
Delay discounting water rate 24 sec0.81.11.6-1.21.10.01.2-1.31.30.6
Delay discounting water rate 6 sec2.23.24.1-2.01.80.92.0-2.02.01.7
Locomotor activity0.00.00.0-0.2-0.2-0.10.20.1-0.1-0.1
Locomotor testing distance0.00.00.1-0.3-0.1-0.20.3-0.00.00.1
Locomotor testing rearing0.50.81.1-0.90.80.80.9-1.01.01.0
Light reinforcement 10.10.10.40.3-0.4-0.6-0.30.3-0.3-0.0
Light reinforcement 20.70.91.7-1.30.8-0.01.3-0.90.90.9
Reaction time number correct0.50.71.0-1.00.90.61.0-0.80.80.9
Reaction time mean minus median0.30.41.7-0.3-0.3-1.30.30.4-0.4-0.4
Reaction time mean minus median AUC0.30.41.00.1-0.6-1.0-0.10.7-0.7-0.5
Reaction time num false alarms1.11.53.50.7-1.4-1.9-0.71.2-1.2-1.3
Reaction time num false alarms AUC1.31.83.10.9-1.4-1.8-0.91.3-1.3-1.5
Reaction time trials correct on left0.50.71.0-1.00.90.61.0-0.80.80.9
Reaction time trials on left0.60.81.2-1.10.90.61.1-0.90.90.9
Reaction time mean0.30.51.0-1.00.5-0.71.0-0.40.40.4
Reaction time mean AUC0.50.71.5-1.20.7-0.61.2-0.60.60.7
Median of all reaction times0.40.51.0-1.00.7-0.31.0-0.60.60.6
Reaction time omissions1.82.53.8-1.91.40.71.9-1.41.41.8
Reaction time false alarm rate2.13.03.61.5-1.9-1.8-1.51.7-1.7-1.9
Reaction time premature initiation rate0.40.50.8-0.90.60.30.9-0.80.80.4
Reaction time premature initiations0.71.11.6-1.30.90.41.3-1.11.10.8
Std. dev. reaction times0.30.41.0-1.00.4-0.71.0-0.30.30.4
Reaction time trials completed0.60.81.2-1.10.90.61.1-0.90.90.9
Reaction time trials AUC0.50.71.1-1.00.90.51.0-0.80.80.8
Social response proportion0.80.81.8-0.50.81.30.5-0.90.91.1
Social responses0.20.20.4-0.60.3-0.20.6-0.30.30.6
Social time0.10.20.40.6-0.4-0.2-0.60.4-0.4-0.1
Conditioned locomotion0.20.20.40.6-0.3-0.2-0.60.5-0.5-0.3
Cocaine response after cond. corrected1.21.32.7-0.91.21.60.9-1.11.11.2
Cocaine response after cond. not corrected0.60.61.5-0.50.81.20.5-0.70.70.8
Cocaine response before conditioning1.62.02.51.3-1.6-1.3-1.31.4-1.4-1.5
Saline control response0.10.10.9-0.0-0.2-0.90.00.1-0.1-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.4-0.30.0-0.40.4-0.4-0.2
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.2-0.5-0.10.3-0.3-0.2
Condit. Reinf. active responses1.21.61.81.4-1.3-0.7-1.41.3-1.3-1.3
Condit. Reinf. inactive responses1.41.72.21.3-1.4-0.8-1.31.3-1.3-1.5
Condit. Reinf. lever presses0.20.30.40.6-0.6-0.3-0.60.5-0.5-0.6
Condit. Reinf. lever reinforcers received1.52.12.51.5-1.5-1.0-1.51.6-1.6-1.5
Pavlov. Cond. lever latency0.40.50.8-0.90.70.10.9-0.80.80.5
Pavlov. Cond. magazine entry latency0.10.20.3-0.40.20.30.4-0.40.40.5
Pavlov. Cond. change in total contacts0.50.71.30.5-0.9-1.1-0.51.0-1.0-0.7
Pavlov. Cond. index score0.00.00.2-0.1-0.3-0.40.10.2-0.20.1
Pavlov. Cond. latency score0.00.00.1-0.20.00.10.2-0.10.10.4
Pavlov. Cond. lever contacts0.40.60.80.8-0.7-0.5-0.80.9-0.9-0.5
Pavlov. Cond. magazine entry number0.20.20.5-0.20.60.70.2-0.50.50.4
Pavlov. Cond. intertrial magazine entries0.20.31.4-0.1-0.5-1.20.10.4-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.1-0.2-0.30.10.1-0.10.2
Pavlov. Cond. response bias0.40.50.70.7-0.7-0.5-0.70.9-0.9-0.5
Conditioned reinforcement - actives0.90.91.5-1.20.8-0.71.2-0.80.80.9
Conditioned reinforcement - inactives0.10.20.3-0.40.50.10.4-0.50.50.3
Conditioned locomotion0.40.53.2-0.4-0.1-1.80.40.0-0.0-0.5
Intermittent access intake day 1-15 change0.70.71.20.6-0.8-1.1-0.60.8-0.8-0.8
Intermittent access intake escalation0.20.20.30.5-0.5-0.3-0.50.5-0.5-0.4
Intermittent access intake escalation 20.00.00.2-0.1-0.1-0.40.10.1-0.1-0.2
Intermitt. access day 1 inactive lever presses0.50.52.60.20.61.6-0.2-0.40.40.6
Intermitt. access day 15 inactive lever presses1.01.12.21.5-0.80.7-1.50.8-0.8-0.8
Intermitt. access escalation Index0.60.51.0-1.00.7-0.41.0-0.60.60.5
Intermittent access day 1 total infusions0.30.30.4-0.20.60.60.2-0.70.70.6
Intermittent access day 15 total infusions0.00.00.10.20.1-0.3-0.2-0.00.00.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.00.2-0.10.0-0.20.20.3
Intermittent access total infusions0.00.00.30.00.0-0.6-0.00.0-0.00.0
Intermittent access day 1 locomotion0.10.10.30.5-0.1-0.5-0.50.0-0.0-0.0
Intermittent access day 15 total locomotion1.01.13.60.5-0.8-1.9-0.50.8-0.8-1.2
Intermittent access total locomotion0.50.53.30.2-0.3-1.8-0.20.3-0.3-0.3
Intermittent access standard deviation3.03.25.12.3-1.7-0.2-2.31.7-1.7-1.9
Cocaine induced anxiety0.50.60.9-0.90.70.60.9-0.80.80.4
Post-drug Anxiety0.10.10.2-0.3-0.10.40.3-0.00.0-0.3
Baseline Anxiety1.11.21.51.1-1.1-0.2-1.11.2-1.2-1.2
Lifetime Intake0.10.10.70.2-0.2-0.8-0.20.2-0.2-0.2
Incentive Sensitization - Responses1.81.85.40.4-1.2-2.3-0.41.2-1.2-1.6
Incentive Sensitization - Breakpoint1.81.85.30.4-1.2-2.3-0.41.2-1.2-1.6
Progressive ratio test 1 active lever presses0.20.20.8-0.30.3-0.90.3-0.30.30.4
Progressive ratio test 1 breakpoint0.20.31.1-0.40.3-1.10.4-0.30.30.3
Progressive ratio test 1 inactive lever presses0.10.10.20.00.30.1-0.0-0.30.30.4
Progressive ratio test 2 active lever presses0.40.42.9-0.3-0.1-1.70.30.1-0.1-0.2
Progressive ratio test 2 breakpoint0.60.74.3-0.4-0.2-2.10.40.2-0.2-0.4
Progressive ratio test 2 inactive lever presses0.50.61.40.5-0.7-1.2-0.50.7-0.7-0.7
Total sessions with >9 infusions0.20.20.40.6-0.2-0.6-0.60.2-0.2-0.5
Short access day 1 total inactive lever presses1.61.82.6-1.01.61.61.0-1.41.41.2
Short access day 10 total inactive lever presses5.46.025.9-0.02.05.10.0-1.81.82.3
Short access day 1 total infusions0.10.10.2-0.20.4-0.00.2-0.40.40.2
Short access day 10 total infusions0.30.40.90.9-0.30.7-0.90.3-0.30.0
Short access total infusions0.30.30.50.7-0.5-0.7-0.70.5-0.5-0.5
Short access day 1 locomotion0.40.41.31.2-0.30.1-1.20.3-0.3-0.3
Short access day 10 total locomotion0.70.71.31.1-0.7-0.8-1.10.6-0.6-0.7
Short access total locomotion0.60.61.21.1-0.5-0.9-1.10.6-0.6-0.6
Compulsive drug intake1.11.11.6-1.11.00.61.1-1.11.11.3
One hour access (0.3 mA shock)0.30.31.2-0.60.1-1.10.6-0.20.20.3
One hour access (shock baseline)0.70.91.00.8-1.0-1.0-0.81.0-1.0-1.0
Number of responses in last shaping day0.70.71.3-0.60.90.80.6-0.90.91.1
Context. condit. distance diff. score0.00.00.10.1-0.3-0.2-0.10.2-0.1-0.2
Locomotion velocity, session 10.60.72.31.0-0.21.5-1.00.4-0.4-0.1
Locomotion distance, session 11.72.25.80.8-1.5-2.4-0.81.5-1.5-1.1
Locomotion velocity, session 20.00.00.10.2-0.20.4-0.20.10.00.2
Locomotion distance, session 22.84.15.61.6-2.2-2.4-1.62.1-2.2-1.8
Locomotion velocity, session 30.20.30.40.6-0.6-0.0-0.60.6-0.6-0.1
Locomotion distance, session 31.81.95.40.7-1.5-2.3-0.71.3-1.3-1.1
Stereotopy head waving bouts, day 30.30.41.4-0.30.61.20.3-0.40.40.6
Stereotopy head waving duration, day 30.60.83.5-0.00.91.90.0-0.60.60.6
Locomotion velocity, session 70.50.61.21.1-0.51.1-1.10.4-0.4-0.3
Locomotion distance, session 70.91.11.90.8-1.4-1.2-0.81.1-1.1-0.7
Stereotopy head waving bouts, day 70.30.31.40.70.21.2-0.70.2-0.2-0.2
Stereotopy head waving duration, day 70.60.82.91.10.21.7-1.10.2-0.2-0.4
Locomotion velocity, session 80.00.00.10.2-0.2-0.3-0.20.1-0.10.2
Locomotion distance, session 82.13.23.91.5-2.0-1.9-1.51.9-1.9-1.7
Degree of sensitization distance0.20.20.5-0.30.30.70.3-0.50.50.5
Degree of sensitization stereotypy0.30.41.10.80.01.0-0.80.3-0.3-0.3
Condit. Reinf. active minus inactive responses0.30.30.60.8-0.60.1-0.80.5-0.6-0.4
Condit. Reinf. active-inactive response ratio0.20.20.7-0.20.30.80.2-0.30.20.5
Condit. Reinf. active responses0.50.61.01.0-0.8-0.1-1.00.8-0.8-0.6
Condit. Reinf. inactive responses0.91.12.20.8-1.1-1.5-0.81.0-1.0-1.0
Incentive salience index mean0.30.40.70.9-0.50.5-0.90.4-0.5-0.3
Condit. Reinf. lever presses0.10.20.30.6-0.30.4-0.60.3-0.3-0.2
Time in familiar zone, hab. session 10.10.10.3-0.50.3-0.30.5-0.30.30.3
Time in novel zone, hab. session 10.60.61.21.1-0.60.4-1.10.7-0.7-0.7
Total zone transitions, hab. session 11.72.43.21.4-1.8-1.7-1.41.7-1.6-1.1
Total locomotion distance, hab. session 10.30.41.70.1-0.8-1.3-0.10.6-0.6-0.1
Locomotion velocity, hab. session 10.30.41.9-0.5-0.4-1.40.50.3-0.20.3
Time in familiar zone, hab. session 20.10.10.2-0.20.20.30.2-0.10.10.4
Time in novel zone, hab. session 20.20.20.20.5-0.4-0.2-0.50.3-0.3-0.4
Total zone transitions, hab. session 20.10.20.50.3-0.4-0.7-0.30.5-0.5-0.2
Total locomotion distance, hab. session 20.30.40.7-0.90.3-0.60.9-0.40.40.8
Locomotion velocity, hab. session 20.20.30.9-0.70.1-0.90.7-0.10.10.5
Novel to familiar place preference ratio0.50.60.91.0-0.80.1-1.00.7-0.6-0.7
Novelty place preference0.60.61.01.0-0.8-0.0-1.00.8-0.7-0.7
Time in novel zone, NPP test0.40.40.70.9-0.70.2-0.90.6-0.5-0.5
Total zone transitions, NPP test1.01.42.50.9-1.3-1.6-0.91.2-1.3-1.1
Total locomotion distance, NPP test0.60.82.60.2-1.0-1.6-0.20.9-1.0-0.5
Locomotion velocity, NPP test0.91.23.90.3-1.2-2.0-0.31.1-1.2-0.8
Pavlov. Cond. lever latency1.31.62.51.3-1.2-1.0-1.31.2-1.3-1.6
Pavlov. Cond. magazine entry latency0.30.40.8-0.80.50.40.8-0.50.60.9
Pavlov. Cond. change in total contacts0.00.00.10.2-0.20.1-0.20.2-0.10.2
Pavlov. Cond. index score0.70.91.7-0.90.80.70.9-0.80.91.3
Pavlov. Cond. latency score1.21.52.5-1.21.11.01.2-1.11.21.6
Pavlov. Cond. lever contacts1.21.42.1-1.31.10.71.3-1.11.11.5
Pavlov. Cond. magazine entry number0.50.61.20.8-0.7-0.6-0.80.7-0.7-1.1
Pavlov. Cond. intertrial magazine entries0.70.81.11.0-1.0-0.7-1.00.9-1.0-0.7
Pavlov. Cond. lever-magazine prob. diff.1.21.52.6-1.21.11.01.2-1.11.21.6
Pavlov. Cond. response bias0.30.40.9-0.70.50.40.7-0.50.50.9
Bone: apparent density3.76.18.02.8-2.6-0.8-2.82.6-2.6-2.4
Bone surface3.86.88.12.8-2.8-1.2-2.82.8-2.8-2.4
Bone volume3.55.97.22.7-2.7-1.0-2.72.6-2.6-2.2
Bone: connectivity density4.46.99.13.0-2.8-0.8-3.02.8-2.8-2.5
Bone: cortical apparent density1.72.23.3-1.81.30.71.8-1.51.51.4
Bone: cortical area0.20.40.60.8-0.70.2-0.80.5-0.5-0.3
Bone: cortical porosity1.31.51.81.3-1.2-0.6-1.31.2-1.2-1.3
Bone: cortical porosity0.70.81.01.0-1.0-0.4-1.00.9-0.9-0.9
Bone: cortical thickness0.10.20.5-0.00.10.70.0-0.40.40.5
Bone: cortical thickness0.91.11.4-1.00.90.71.0-1.21.21.1
Bone: cortical tissue density2.02.63.9-2.01.50.82.0-1.71.71.5
Bone: elastic displacement0.10.10.2-0.40.1-0.30.4-0.30.30.2
Bone: elastic work0.10.10.1-0.20.20.30.2-0.30.30.3
Bone: endosteal estimation0.40.81.10.8-1.1-0.9-0.80.9-0.9-0.9
Bone: endosteal perimeter0.51.01.50.9-1.2-0.9-0.91.1-1.1-1.0
Bone: final force0.40.60.91.0-0.9-0.0-1.00.8-0.8-0.7
Bone: final moment0.40.61.01.0-0.80.1-1.00.7-0.7-0.6
Bone: marrow area0.30.71.10.8-1.0-0.8-0.80.9-0.9-0.8
Bone: maximum diameter0.30.51.00.7-1.0-0.5-0.70.7-0.7-0.5
Bone: maximum force0.20.40.70.8-0.70.2-0.80.6-0.6-0.4
Bone: maximum moment0.20.40.70.8-0.60.3-0.80.6-0.6-0.3
Bone: minimum diameter0.51.01.31.1-1.1-0.6-1.11.0-1.0-0.9
Bone: periosteal estimation0.51.01.51.1-1.2-0.5-1.11.0-1.0-0.8
Bone: periosteal perimeter0.40.61.10.9-1.1-0.1-0.90.8-0.8-0.6
Bone: post-yield work0.30.40.80.9-0.60.5-0.90.6-0.6-0.3
Bone: stiffness0.60.91.31.1-1.00.0-1.11.0-1.0-0.8
Bone: tissue strength0.60.60.80.9-0.7-0.1-0.90.9-0.9-0.7
Bone: trabecular number2.64.05.02.2-2.1-0.7-2.22.2-2.2-2.0
Bone: trabecular spacing1.01.31.5-1.01.21.21.0-1.21.21.1
Bone: trabecular thickness0.91.11.61.2-1.3-0.7-1.21.0-1.0-0.9
Bone: trabecular tissue density1.31.82.7-1.61.1-0.01.6-1.41.41.3
Breakpoint value in progressive ratio session0.30.30.6-0.80.6-0.20.7-0.60.50.4
Distance traveled before self-admin0.60.61.21.0-0.21.1-1.00.4-0.7-0.4
Distance traveled after self-admin0.00.10.10.10.30.30.0-0.30.20.2
Delta time in closed arm before/after self-admin0.00.00.20.1-0.4-0.3-0.10.2-0.1-0.0
Delta time in open arm before/after self-admin0.60.61.1-0.50.91.00.3-0.90.70.9
Diff in mean of infusions in LGA sessions0.91.02.80.4-0.8-1.3-0.60.9-0.7-1.7
Extinction: sum of active levers before priming0.00.00.10.30.10.0-0.00.20.3-0.2
Active lever presses in extinction session 60.10.10.3-0.50.40.40.4-0.40.10.0
Delta distance traveled before/after self-admin0.40.42.4-0.3-0.3-1.50.30.10.1-0.6
Delta ambulatory time before/after self-admin0.50.51.0-0.90.5-0.91.0-0.60.70.2
Time in closed arm before self-admin0.70.81.2-1.11.0-0.61.1-0.80.70.7
Time in closed arm after self-admin0.20.20.4-0.60.2-0.70.5-0.20.0-0.0
Time in open arm before self-admin0.30.31.2-0.3-0.5-1.10.40.3-0.3-0.6
Time in open arm after self-admin1.21.31.5-1.11.11.11.1-1.21.21.2
Sum of active levers in priming session hrs 5-60.00.00.10.3-0.1-0.0-0.30.2-0.1-0.3
Time to tail flick, vehicle, before self-admin2.92.94.11.1-1.8-2.0-1.11.7-1.9-2.0
Time to tail flick, vehicle, after self-admin1.21.22.20.8-1.3-1.0-1.01.2-1.5-0.9
Time to tail flick, test, before self-admin4.44.46.11.6-1.9-2.3-1.62.2-2.5-2.4
Time to tail flick, test, after self-admin0.40.40.9-0.90.6-0.80.9-0.50.3-0.2
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.40.50.50.3-0.40.21.0
Delta time to tail flick, test, before/after SA2.62.33.2-1.71.60.51.8-1.61.71.4
Ambulatory time before self-admin1.11.12.01.4-0.80.4-1.40.9-1.1-1.0
Ambulatory time after self-admin0.00.10.20.10.2-0.40.1-0.30.30.0
Total heroin consumption0.10.10.30.1-0.30.0-0.20.3-0.5-0.2
Area under the delay curve0.10.20.30.2-0.20.5-0.20.6-0.5-0.4
Delay disc. indifference point, 0s delay0.10.10.1-0.40.1-0.10.4-0.10.2-0.3
Delay disc. indifference point, 16s delay0.60.60.90.9-0.70.3-0.90.9-1.0-0.6
Delay disc. indifference point, 2s delay0.80.91.40.7-1.0-0.5-0.71.2-1.1-1.0
Delay disc. indifference point, 24s delay0.30.30.70.5-0.4-0.4-0.50.6-0.6-0.8
Delay disc. indifference point, 4s delay0.10.10.30.2-0.10.2-0.20.6-0.5-0.6
Delay disc. indifference point, 8s delay0.10.10.70.00.20.8-0.00.2-0.3-0.2
Delay discount exponential model param0.20.20.5-0.40.2-0.40.4-0.70.70.5
Delay discount hyperbolic model param0.40.40.8-0.50.5-0.30.5-0.90.80.7
Fecal boli incidents, locomotor time 10.50.61.4-0.60.61.20.6-0.60.60.9
Change in fecal boli incidents, locomotor task2.12.02.5-1.41.60.91.4-1.61.51.4
Time >=10cm from walls, locomotor time 11.51.54.7-0.81.02.20.8-1.01.11.1
Bouts of movement, locomotor time 13.03.35.41.3-2.1-2.3-1.31.9-1.7-2.0
Total resting periods, locomotor time 12.42.73.81.3-1.9-1.9-1.31.7-1.6-1.7
Rest time, locomotor task time 10.10.10.2-0.30.30.30.3-0.40.40.5
Distance moved, locomotor task time 11.21.32.1-1.11.20.81.1-1.11.21.4
Vertical activity count, locomotor time 10.80.81.3-1.11.00.11.1-0.80.90.9
Time >=10cm from walls, locomotor time 20.20.20.5-0.10.30.70.1-0.40.40.4
Bouts of movement, locomotor time 21.71.82.01.3-1.4-1.4-1.31.4-1.3-1.3
Total resting periods, locomotor time 21.51.61.81.3-1.3-0.9-1.31.4-1.2-1.2
Rest time, locomotor task time 20.10.20.5-0.30.50.70.3-0.30.40.3
Distance moved, locomotor task time 21.01.11.6-1.20.9-0.51.2-1.11.11.2
Vertical activity count, locomotor time 21.01.11.8-1.40.9-0.61.4-1.01.10.8
Weight adjusted by age0.00.00.2-0.1-0.2-0.40.10.2-0.2-0.0
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.30.6-0.1-0.00.0-0.3
Locomotion in novel chamber0.50.61.01.0-0.80.2-1.00.8-0.8-0.7
Locomotion in novel chamber post-restriction0.10.10.30.2-0.5-0.5-0.2-0.00.0-0.0
Progressive ratio0.30.30.50.4-0.6-0.7-0.40.6-0.6-0.7
Food seeking constrained by brief footshock0.30.41.90.20.41.4-0.20.4-0.40.3
Seeking ratio, punishment vs. effort0.20.31.1-0.10.61.10.1-0.20.20.6
Run reversals in cocaine runway, females0.10.10.30.2-0.20.5-0.20.1-0.10.3
Run reversals in cocaine runway, males1.21.12.01.1-0.9-0.3-1.11.2-1.2-1.4
Latency to leave start box in cocaine runway2.52.74.2-1.31.61.81.3-1.71.72.0
Latency to leave start box in cocaine runway, F1.31.44.0-0.51.12.00.5-1.01.01.4
Latency to leave start box in cocaine runway, M0.30.30.6-0.60.2-0.20.6-0.60.60.8
Cd content in liver0.40.41.20.9-0.21.1-0.90.3-0.3-0.4
Co content in liver0.30.41.80.50.21.3-0.5-0.10.1-0.1
Cu content in liver0.30.30.60.4-0.8-0.6-0.40.6-0.6-0.5
Fe content in liver0.20.30.40.3-0.6-0.7-0.30.6-0.6-0.3
K content in liver1.81.83.1-1.81.1-0.71.8-1.21.21.2
Mg content in liver3.13.25.7-2.41.6-0.52.4-1.61.61.7
Mn content in liver1.41.73.1-1.81.1-0.51.8-1.21.21.0
Na content in liver0.91.01.6-1.30.9-0.21.3-1.01.00.9
Rb content in liver0.30.41.5-0.80.1-1.20.80.1-0.10.3
Se content in liver0.10.10.6-0.3-0.3-0.80.3-0.10.10.2
Sr content in liver0.50.51.9-0.00.71.40.0-0.70.70.3
Zn content in liver0.91.01.61.2-1.0-0.3-1.20.9-0.9-1.1