Zfp84

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000029043	0.23	0.16	2.0e-06	0.08	0.1	0.08	0.09	5.5e-05	3.4e-06	4.4e-05	2.8e-05
2	Eye	gene expression	ENSRNOG00000029043	0.33	0.19	3.9e-03	0.02	-0	-0.02	-0.02	1.4e-01	3.5e-01	9.4e-01	7.1e-01
3	IL	gene expression	ENSRNOG00000029043	0.23	0.2	4.1e-03	0.09	0.04	0.07	0.12	3.1e-03	5.2e-02	9.5e-03	9.0e-04
4	Liver	gene expression	ENSRNOG00000029043	0.46	0.25	0.0e+00	0.23	0.23	0.24	0.23	1.2e-25	1.0e-25	4.6e-26	2.0e-25
5	NAcc	gene expression	ENSRNOG00000029043	0.14	0.09	1.2e-06	0.08	0.08	0.08	0.09	8.6e-07	1.9e-06	1.2e-06	3.6e-07
6	PL	gene expression	ENSRNOG00000029043	0.06	0.04	1.4e-05	0.05	0.06	0.03	0.05	1.5e-04	2.4e-05	1.9e-03	2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
BMI with tail	0.4	1.3	2.0	-1.2	1.4	-0.4	1.4	-1.0	-1.2
BMI without tail	0.1	0.3	0.6	0.6	-0.4	0.8	-0.5	0.3	0.4
Body weight	2.4	10.1	13.6	3.2	-2.9	3.7	-3.0	3.1	3.1
Epididymis fat weight	0.0	0.0	0.1	-0.1	0.3	0.0	0.3	-0.1	-0.0
Glucose	0.2	0.3	0.4	-0.6	0.5	-0.5	0.6	-0.5	-0.6
Heart weight	0.3	0.4	1.0	0.5	-0.5	1.0	-0.6	0.4	0.5
Left kidney weight	1.5	4.3	9.7	2.0	-1.6	3.1	-1.6	1.9	1.9
Right kidney weight	3.6	10.2	13.7	3.2	-3.0	3.7	-2.9	3.2	3.2
Tail length	6.1	18.6	20.7	4.5	-4.4	4.1	-4.4	4.2	4.1
Length with tail	8.9	32.5	35.1	5.9	-5.8	5.4	-5.8	5.6	5.6
Length without tail	4.1	8.9	9.9	3.1	-2.9	2.8	-2.9	3.0	3.1
Liver weight, left	0.5	0.8	1.1	-0.8	1.0	-0.1	1.0	-0.9	-1.1
Liver weight, right	0.0	0.0	0.1	-0.0	0.3	0.1	0.2	-0.2	-0.3
Parametrial fat weight	0.9	1.8	2.5	-1.3	1.6	-0.9	1.5	-1.6	-1.1
Retroperitoneal fat weight	1.8	6.0	7.6	-2.5	2.7	-1.6	2.8	-2.4	-2.6
Intraocular pressure	0.0	0.1	0.2	0.1	-0.4	-0.1	-0.2	0.4	0.2
Extensor digitorum longus weight	0.2	0.7	0.9	-0.8	0.7	-0.9	0.8	-0.9	-0.9
Soleus weight	0.4	1.0	2.7	-0.9	0.7	-1.6	0.9	-1.0	-0.7
Tibialis anterior weight	0.0	0.1	0.2	-0.2	0.3	0.0	0.3	-0.1	-0.4
Tibia length	1.7	4.8	5.8	2.2	-2.0	2.4	-2.1	2.1	2.3
Number of licking bursts	3.0	3.6	4.6	-1.8	1.9	-1.7	2.0	-1.7	-2.1
Food consumed during 24 hour testing period	0.6	0.7	1.0	0.8	-0.8	0.4	-0.9	1.0	1.0
Times rat made contact with spout	1.1	1.3	1.7	-1.2	1.3	-0.5	1.3	-1.1	-1.2
Mean time between licks in bursts	0.0	0.1	0.2	0.3	-0.0	0.4	-0.2	0.2	0.1
Mean num. licks in bursts	0.7	0.9	1.3	0.8	-0.8	1.1	-0.9	0.8	1.1
Std. dev. time between licks in bursts	1.1	1.3	1.8	1.3	-1.2	1.0	-1.3	1.0	1.1
Water consumed over 24 hours	0.2	0.3	1.2	0.3	-0.1	1.1	-0.2	0.4	0.4
Indifference point 0 sec	0.1	0.2	0.3	0.5	-0.3	0.4	-0.4	0.6	0.4
Indifference point AUC	0.5	0.6	0.9	-0.8	0.9	-0.5	0.9	-0.8	-0.8
Indifference point function ln k	0.5	0.7	0.9	0.7	-0.9	0.6	-0.9	0.9	1.0
Indifference point function log k	0.5	0.7	0.9	0.7	-0.9	0.6	-0.9	0.9	1.0
Delay discounting total patch changes 0 sec	0.2	0.4	0.7	0.7	-0.5	0.5	-0.6	0.8	0.6
Delay discounting total patch changes 12 sec	0.1	0.2	0.3	0.3	-0.2	0.5	-0.4	0.5	0.3
Delay discounting total patch changes 18 sec	0.2	0.3	0.7	-0.4	0.8	-0.3	0.6	-0.5	-0.5
Delay discounting total patch changes 24 sec	0.8	1.0	1.3	1.1	-0.9	0.8	-1.0	1.1	0.9
Delay discounting total patch changes 6 sec	0.0	0.0	0.1	0.3	0.1	0.3	-0.0	0.1	-0.0
Delay discounting time to switch 0 sec	0.6	0.9	1.6	-0.9	0.9	-1.3	0.7	-1.1	-0.7
Delay discounting water rate 0 sec	0.7	1.0	1.3	-1.0	1.1	-0.8	1.1	-1.0	-1.1
Delay discounting water rate 12 sec	0.8	1.1	1.9	1.4	-1.0	0.9	-1.0	1.2	0.8
Delay discounting water rate 18 sec	0.2	0.3	1.3	-0.2	0.0	-1.1	0.1	-0.4	-0.3
Delay discounting water rate 24 sec	0.1	0.2	0.3	0.5	-0.5	0.5	-0.5	0.3	0.2
Delay discounting water rate 6 sec	0.3	0.5	0.9	0.9	-0.7	0.1	-0.7	0.6	0.9
Locomotor activity	0.7	1.1	1.5	-1.2	1.0	-0.6	1.2	-1.1	-0.9
Locomotor testing distance	0.9	1.5	1.8	-1.4	1.1	-1.3	1.3	-1.2	-1.0
Locomotor testing rearing	2.1	3.3	4.0	-1.8	1.8	-1.5	1.8	-2.0	-2.0
Light reinforcement 1	0.1	0.2	0.3	-0.4	0.5	-0.5	0.5	-0.3	-0.5
Light reinforcement 2	4.7	6.2	9.2	-2.5	2.3	-3.0	2.4	-2.6	-2.0
Reaction time number correct	0.2	0.3	0.5	-0.5	0.7	0.2	0.6	-0.7	-0.6
Reaction time mean minus median	0.1	0.2	0.3	0.6	-0.4	0.5	-0.3	0.4	0.4
Reaction time mean minus median AUC	0.2	0.3	0.6	0.8	-0.4	0.6	-0.4	0.3	0.5
Reaction time num false alarms	1.1	1.6	2.0	-1.2	1.3	-0.9	1.4	-1.2	-1.4
Reaction time num false alarms AUC	1.5	2.2	2.7	-1.5	1.5	-1.2	1.6	-1.4	-1.5
Reaction time trials correct on left	0.2	0.3	0.5	-0.5	0.7	0.2	0.6	-0.7	-0.6
Reaction time trials on left	0.3	0.4	0.6	-0.5	0.7	0.2	0.6	-0.8	-0.6
Reaction time mean	0.0	0.1	0.2	-0.1	0.2	-0.2	0.4	-0.2	-0.1
Reaction time mean AUC	0.2	0.2	0.5	-0.4	0.5	-0.4	0.7	-0.5	-0.4
Median of all reaction times	0.2	0.2	0.4	-0.4	0.4	-0.5	0.7	-0.4	-0.4
Reaction time omissions	0.3	0.4	0.8	-0.4	0.7	-0.4	0.6	-0.9	-0.5
Reaction time false alarm rate	0.7	0.9	1.3	-1.0	0.8	-1.2	1.0	-0.8	-1.0
Reaction time premature initiation rate	0.1	0.2	0.3	0.4	-0.6	-0.0	-0.5	0.3	0.5
Reaction time premature initiations	0.0	0.0	0.0	0.0	-0.1	0.1	-0.1	-0.1	0.1
Std. dev. reaction times	0.1	0.1	0.2	0.5	-0.3	0.3	-0.1	0.2	0.3
Reaction time trials completed	0.3	0.4	0.6	-0.5	0.7	0.2	0.6	-0.8	-0.6
Reaction time trials AUC	0.4	0.6	1.0	-0.7	0.9	0.1	0.8	-1.0	-0.7
Social response proportion	3.3	3.6	4.8	1.8	-1.9	2.2	-2.0	1.6	2.0
Social responses	0.3	0.4	1.1	0.6	-0.6	0.3	-0.7	0.4	1.1
Social time	1.8	2.4	3.6	1.6	-1.7	0.7	-1.6	1.5	1.9
Conditioned locomotion	0.2	0.2	0.5	-0.5	0.4	0.7	0.2	-0.5	-0.5
Cocaine response after cond. corrected	0.1	0.2	0.6	0.4	-0.3	0.8	-0.3	0.2	-0.0
Cocaine response after cond. not corrected	0.2	0.2	1.0	0.2	-0.0	1.0	-0.0	0.1	-0.0
Cocaine response before conditioning	0.5	0.6	1.9	0.5	-0.3	1.4	-0.4	0.5	0.8
Saline control response	0.2	0.3	0.6	0.5	-0.6	0.8	-0.5	0.6	0.3
Condit. Reinf. active minus inactive responses	3.2	4.0	4.9	2.0	-1.9	2.2	-2.0	2.0	1.9
Condit. Reinf. active-inactive response ratio	0.9	0.9	3.0	0.9	-0.7	1.7	-0.7	0.9	0.3
Condit. Reinf. active responses	4.4	6.2	6.4	2.5	-2.4	2.5	-2.5	2.5	2.5
Condit. Reinf. inactive responses	3.0	3.7	5.5	2.0	-1.9	1.2	-2.0	1.9	2.3
Condit. Reinf. lever presses	9.2	12.7	14.6	3.6	-3.8	2.8	-3.7	3.7	3.6
Condit. Reinf. lever reinforcers received	4.9	6.9	7.3	2.7	-2.5	2.7	-2.6	2.6	2.6
Pavlov. Cond. lever latency	4.7	6.5	7.6	-2.6	2.8	-1.9	2.6	-2.5	-2.7
Pavlov. Cond. magazine entry latency	3.2	3.6	4.4	1.9	-2.1	1.3	-2.0	1.9	2.1
Pavlov. Cond. change in total contacts	8.6	12.0	13.3	3.6	-3.7	2.7	-3.6	3.5	3.6
Pavlov. Cond. index score	5.0	6.5	8.0	2.6	-2.8	1.7	-2.7	2.6	2.7
Pavlov. Cond. latency score	4.7	6.0	7.3	2.5	-2.7	1.7	-2.6	2.5	2.6
Pavlov. Cond. lever contacts	4.5	6.3	7.6	2.6	-2.8	1.9	-2.6	2.5	2.6
Pavlov. Cond. magazine entry number	3.2	3.9	5.0	-2.0	2.2	-1.0	2.1	-2.0	-2.2
Pavlov. Cond. intertrial magazine entries	2.0	2.5	3.4	-1.6	1.8	-1.1	1.8	-1.6	-1.5
Pavlov. Cond. lever-magazine prob. diff.	5.1	6.6	8.0	2.6	-2.8	1.9	-2.7	2.6	2.7
Pavlov. Cond. response bias	5.0	6.9	8.0	2.7	-2.8	2.0	-2.7	2.7	2.7
Conditioned reinforcement - actives	0.1	0.1	0.5	0.1	-0.1	0.7	-0.2	0.1	-0.2
Conditioned reinforcement - inactives	1.7	1.9	2.8	1.4	-1.3	1.7	-1.4	1.4	1.1
Conditioned locomotion	2.2	2.6	3.3	-1.8	1.8	-1.0	1.6	-1.7	-1.6
Intermittent access intake day 1-15 change	1.9	1.9	2.4	1.5	-1.3	1.2	-1.3	1.6	1.3
Intermittent access intake escalation	1.6	1.6	2.0	1.4	-1.1	1.1	-1.3	1.4	1.2
Intermittent access intake escalation 2	2.9	2.9	3.6	1.7	-1.6	1.9	-1.6	1.9	1.4
Intermitt. access day 1 inactive lever presses	1.9	2.1	3.6	1.4	-1.4	0.7	-1.4	1.5	1.9
Intermitt. access day 15 inactive lever presses	0.8	0.9	1.4	1.0	-1.1	0.4	-1.0	1.2	0.9
Intermitt. access escalation Index	0.1	0.1	0.2	0.1	-0.4	0.1	-0.2	0.3	-0.1
Intermittent access day 1 total infusions	0.9	1.0	1.9	-1.1	0.9	-0.2	1.0	-1.0	-1.4
Intermittent access day 15 total infusions	0.4	0.4	0.8	0.6	-0.6	0.9	-0.6	0.7	0.2
Intermittent access terminal intake (last 3 days)	0.5	0.6	1.4	0.6	-0.8	1.2	-0.7	0.8	0.1
Intermittent access total infusions	0.1	0.1	0.4	-0.0	-0.3	0.6	-0.1	0.2	-0.3
Intermittent access day 1 locomotion	0.5	0.5	0.9	-0.9	0.7	0.0	0.8	-0.7	-0.9
Intermittent access day 15 total locomotion	0.1	0.1	0.1	-0.3	0.3	-0.0	0.2	-0.2	-0.2
Intermittent access total locomotion	0.9	1.0	1.4	-1.2	1.0	-0.5	1.1	-1.0	-1.1
Intermittent access standard deviation	6.9	7.4	8.7	2.7	-2.8	2.4	-2.7	2.9	2.6
Cocaine induced anxiety	0.3	0.3	0.6	0.5	-0.7	-0.3	-0.6	0.4	0.8
Post-drug Anxiety	0.2	0.2	1.1	0.1	-0.2	-1.1	-0.2	-0.0	0.2
Baseline Anxiety	0.8	0.8	1.3	-0.9	1.1	-0.2	1.0	-0.9	-1.1
Lifetime Intake	0.2	0.2	0.5	-0.6	0.4	0.1	0.4	-0.4	-0.7
Incentive Sensitization - Responses	0.1	0.1	0.2	0.1	-0.5	-0.2	-0.3	0.3	0.1
Incentive Sensitization - Breakpoint	0.1	0.1	0.1	0.0	-0.4	-0.3	-0.2	0.2	0.0
Progressive ratio test 1 active lever presses	0.6	0.6	1.8	0.5	-0.6	1.4	-0.7	0.7	0.6
Progressive ratio test 1 breakpoint	1.0	1.0	2.3	0.7	-0.8	1.5	-0.9	0.9	0.9
Progressive ratio test 1 inactive lever presses	0.8	0.9	1.1	0.9	-1.0	0.7	-1.0	1.0	0.9
Progressive ratio test 2 active lever presses	0.4	0.4	0.6	0.5	-0.8	0.7	-0.7	0.7	0.4
Progressive ratio test 2 breakpoint	0.3	0.4	0.6	0.4	-0.7	0.7	-0.6	0.7	0.3
Progressive ratio test 2 inactive lever presses	3.8	4.4	5.9	1.9	-2.4	1.7	-2.3	2.4	1.8
Total sessions with >9 infusions	1.4	1.6	2.2	-1.3	1.4	0.2	1.4	-1.3	-1.5
Short access day 1 total inactive lever presses	1.1	1.2	1.8	1.1	-1.3	0.6	-1.3	1.2	0.9
Short access day 10 total inactive lever presses	1.5	1.7	2.7	1.2	-1.4	0.5	-1.5	1.3	1.6
Short access day 1 total infusions	0.1	0.1	0.3	-0.1	0.2	0.6	0.1	-0.1	-0.3
Short access day 10 total infusions	0.7	0.7	1.0	-1.0	0.9	-0.4	1.0	-0.8	-0.9
Short access total infusions	1.1	1.2	1.6	-1.3	1.2	-0.4	1.2	-1.1	-1.3
Short access day 1 locomotion	2.5	2.7	3.8	-1.6	1.9	-0.9	1.8	-1.9	-1.5
Short access day 10 total locomotion	0.2	0.2	0.6	0.3	-0.2	0.8	-0.2	0.5	0.6
Short access total locomotion	1.3	1.4	2.0	-1.3	1.4	-0.1	1.4	-1.1	-1.2
Compulsive drug intake	0.6	0.6	0.8	0.9	-0.7	0.7	-0.9	0.8	0.5
One hour access (0.3 mA shock)	1.7	1.9	2.5	1.4	-1.5	1.1	-1.5	1.6	1.3
One hour access (shock baseline)	0.1	0.1	0.2	0.2	-0.5	0.3	-0.4	0.4	0.3
Number of responses in last shaping day	1.3	1.3	3.4	0.9	-1.0	1.8	-1.0	1.2	0.5
Context. condit. distance diff. score	0.1	0.1	0.1	-0.2	0.4	-0.3	0.1	-0.3	-0.1
Locomotion velocity, session 1	1.5	1.6	3.4	-1.3	1.1	-1.8	1.1	-1.2	-0.9
Locomotion distance, session 1	0.7	0.9	1.5	0.8	-0.9	1.0	-0.8	1.2	0.9
Locomotion velocity, session 2	0.4	0.5	0.7	-0.8	0.8	-0.5	0.6	-0.9	-0.6
Locomotion distance, session 2	1.2	1.7	2.3	-1.5	1.4	-0.7	1.5	-1.1	-1.4
Locomotion velocity, session 3	0.5	0.6	0.9	-0.7	1.0	-0.5	0.7	-0.9	-0.7
Locomotion distance, session 3	4.1	4.4	7.1	2.1	-1.8	2.7	-2.0	2.1	1.9
Stereotopy head waving bouts, day 3	1.3	1.6	2.6	-1.4	1.4	-0.8	1.2	-1.6	-1.1
Stereotopy head waving duration, day 3	2.9	3.5	5.1	-1.9	1.9	-1.8	1.7	-2.3	-1.5
Locomotion velocity, session 7	0.0	0.0	0.2	0.1	-0.1	0.1	-0.3	-0.0	0.4
Locomotion distance, session 7	0.0	0.0	0.1	0.2	0.0	0.3	-0.1	0.2	0.2
Stereotopy head waving bouts, day 7	0.3	0.4	0.8	-0.6	0.6	-0.1	0.5	-0.7	-0.9
Stereotopy head waving duration, day 7	1.5	1.9	2.5	-1.4	1.3	-1.0	1.3	-1.5	-1.6
Locomotion velocity, session 8	4.3	5.2	5.8	-2.4	2.3	-2.0	2.3	-2.4	-2.3
Locomotion distance, session 8	0.5	0.8	1.0	-0.9	1.0	-0.8	0.9	-0.8	-1.0
Degree of sensitization distance	1.9	1.9	3.9	-1.3	1.2	-2.0	1.1	-1.5	-1.0
Degree of sensitization stereotypy	0.3	0.3	0.9	-0.5	0.6	0.1	0.6	-0.4	-1.0
Condit. Reinf. active minus inactive responses	0.3	0.3	0.5	-0.6	0.5	-0.7	0.5	-0.5	-0.5
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.3	-0.4	0.4	-0.6	0.3	-0.5	-0.4
Condit. Reinf. active responses	1.8	2.2	2.8	-1.7	1.5	-1.1	1.6	-1.2	-1.6
Condit. Reinf. inactive responses	1.4	1.7	2.4	-1.6	1.3	-0.7	1.5	-0.9	-1.5
Incentive salience index mean	0.1	0.1	0.2	-0.4	0.4	-0.2	0.4	-0.2	-0.4
Condit. Reinf. lever presses	0.0	0.1	0.2	0.1	-0.1	0.4	-0.1	0.4	0.2
Time in familiar zone, hab. session 1	0.3	0.3	0.4	0.5	-0.6	0.5	-0.6	0.6	0.5
Time in novel zone, hab. session 1	0.4	0.4	0.7	-0.5	0.6	-0.4	0.6	-0.6	-0.8
Total zone transitions, hab. session 1	0.2	0.3	0.8	0.3	-0.4	0.9	-0.3	0.8	0.2
Total locomotion distance, hab. session 1	3.1	4.5	6.1	2.1	-2.2	2.0	-2.0	2.5	1.9
Locomotion velocity, hab. session 1	1.5	2.1	3.2	1.4	-1.5	1.3	-1.4	1.8	1.4
Time in familiar zone, hab. session 2	1.8	1.9	2.9	1.4	-1.5	0.5	-1.6	1.1	1.7
Time in novel zone, hab. session 2	1.1	1.1	1.7	-1.1	1.1	-0.7	1.2	-0.9	-1.3
Total zone transitions, hab. session 2	1.2	1.6	3.0	-1.3	1.4	-0.2	1.5	-0.9	-1.7
Total locomotion distance, hab. session 2	0.1	0.2	0.4	0.3	-0.3	0.7	-0.2	0.5	0.0
Locomotion velocity, hab. session 2	0.1	0.1	0.4	0.0	-0.0	0.6	0.0	0.3	-0.2
Novel to familiar place preference ratio	0.8	0.9	1.7	0.9	-0.9	1.3	-0.7	1.0	0.5
Novelty place preference	0.7	0.7	1.5	0.8	-0.8	1.2	-0.6	1.0	0.4
Time in novel zone, NPP test	0.4	0.4	0.9	0.6	-0.6	1.0	-0.4	0.7	0.1
Total zone transitions, NPP test	0.1	0.2	0.3	-0.5	0.5	-0.4	0.5	-0.2	-0.3
Total locomotion distance, NPP test	2.4	3.4	4.0	1.8	-1.9	1.4	-1.9	2.0	2.0
Locomotion velocity, NPP test	2.8	3.9	4.8	2.0	-2.0	1.6	-2.0	2.2	2.1
Pavlov. Cond. lever latency	0.1	0.1	0.2	0.3	-0.5	-0.5	-0.4	0.1	0.4
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	-0.3	0.2	-0.5	0.3	-0.3	-0.5
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	-0.1	0.1	0.0	0.2	-0.0	-0.3
Pavlov. Cond. index score	0.2	0.3	0.5	-0.5	0.6	0.1	0.6	-0.4	-0.7
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.3	0.4	0.2	0.4	-0.2	-0.5
Pavlov. Cond. lever contacts	0.3	0.3	0.9	0.5	-0.2	1.0	-0.4	0.7	0.3
Pavlov. Cond. magazine entry number	0.2	0.2	0.4	0.4	-0.4	0.4	-0.5	0.3	0.7
Pavlov. Cond. intertrial magazine entries	0.5	0.6	0.8	-0.9	0.8	-0.3	0.8	-0.8	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.6	-0.4	0.6	0.3	0.6	-0.3	-0.8
Pavlov. Cond. response bias	0.0	0.0	0.1	0.0	0.1	0.2	0.1	0.1	-0.2
Bone: apparent density	0.0	0.0	0.1	-0.1	0.1	-0.2	0.2	-0.3	0.3
Bone surface	0.4	0.7	1.4	0.7	-0.9	0.8	-0.8	0.6	1.2
Bone volume	0.4	0.6	1.1	0.7	-0.8	0.8	-0.7	0.6	1.1
Bone: connectivity density	0.2	0.3	0.7	-0.5	0.4	-0.8	0.4	-0.7	0.1
Bone: cortical apparent density	2.6	3.4	3.8	-1.9	1.9	-1.8	1.9	-1.8	-1.8
Bone: cortical area	1.7	2.5	3.3	1.6	-1.5	1.8	-1.5	1.6	1.4
Bone: cortical porosity	2.1	2.3	2.9	-1.6	1.6	-0.7	1.6	-1.7	-1.5
Bone: cortical porosity	2.5	2.7	3.2	-1.7	1.8	-0.8	1.8	-1.8	-1.7
Bone: cortical thickness	0.5	0.8	1.4	0.9	-0.8	1.2	-0.9	0.9	0.7
Bone: cortical thickness	0.8	0.9	1.3	-1.0	1.1	-0.2	1.0	-0.9	-1.0
Bone: cortical tissue density	3.1	4.0	4.3	-2.1	2.1	-1.9	2.1	-1.9	-1.9
Bone: elastic displacement	0.0	0.0	0.0	-0.1	0.0	-0.2	0.0	-0.1	-0.0
Bone: elastic work	1.7	2.3	2.8	1.4	-1.4	1.7	-1.5	1.5	1.5
Bone: endosteal estimation	1.6	3.3	3.7	1.8	-1.9	1.7	-1.8	1.9	1.9
Bone: endosteal perimeter	1.8	3.7	4.1	1.9	-2.0	1.5	-2.0	2.0	2.0
Bone: final force	1.4	2.2	2.9	1.4	-1.4	1.7	-1.4	1.5	1.5
Bone: final moment	1.9	3.2	4.3	1.7	-1.7	2.1	-1.7	1.8	1.8
Bone: marrow area	1.6	3.5	3.9	1.8	-1.9	1.7	-1.8	1.9	2.0
Bone: maximum diameter	1.3	2.4	3.0	1.6	-1.5	1.7	-1.5	1.5	1.5
Bone: maximum force	2.6	4.5	5.0	2.1	-2.1	2.2	-2.0	2.2	2.1
Bone: maximum moment	3.3	5.8	6.6	2.4	-2.4	2.6	-2.3	2.5	2.3
Bone: minimum diameter	4.9	9.1	10.5	3.0	-3.0	3.2	-3.0	3.1	2.8
Bone: periosteal estimation	2.1	4.4	4.6	2.1	-2.1	2.1	-2.1	2.1	2.1
Bone: periosteal perimeter	2.2	3.6	3.9	1.9	-2.0	1.8	-2.0	2.0	1.9
Bone: post-yield work	1.6	2.1	2.7	1.5	-1.6	0.9	-1.5	1.5	1.6
Bone: stiffness	1.4	2.2	2.3	1.5	-1.5	1.5	-1.5	1.5	1.5
Bone: tissue strength	4.2	4.0	4.7	2.2	-1.9	2.1	-2.0	2.0	1.9
Bone: trabecular number	0.2	0.3	0.9	0.5	-0.5	0.4	-0.5	0.4	0.9
Bone: trabecular spacing	1.4	1.8	2.2	1.4	-1.3	1.5	-1.3	1.4	1.0
Bone: trabecular thickness	0.5	0.6	0.8	-0.7	0.8	-0.3	0.9	-0.9	-0.8
Bone: trabecular tissue density	2.5	3.6	4.1	-2.0	1.8	-1.8	1.9	-1.9	-1.9
Breakpoint value in progressive ratio session	3.8	4.3	5.7	1.9	-2.4	1.1	-2.4	2.1	2.2
Distance traveled before self-admin	1.0	1.1	1.8	0.7	-1.2	1.3	-1.0	1.2	0.7
Distance traveled after self-admin	5.6	6.2	7.3	2.4	-2.5	2.4	-2.5	2.7	2.5
Delta time in closed arm before/after self-admin	1.1	1.0	1.7	1.0	-0.9	0.8	-1.0	1.0	1.3
Delta time in open arm before/after self-admin	0.6	0.6	1.2	-0.5	0.7	-0.2	0.9	-0.8	-1.1
Diff in mean of infusions in LGA sessions	0.2	0.2	0.5	0.2	-0.7	0.1	-0.6	0.6	0.4
Extinction: sum of active levers before priming	1.8	1.8	2.8	1.2	-1.4	1.2	-1.2	1.3	1.7
Active lever presses in extinction session 6	1.6	1.6	3.2	1.1	-1.2	0.5	-1.4	1.1	1.8
Delta distance traveled before/after self-admin	2.4	2.6	3.9	1.9	-1.5	0.8	-1.7	1.5	2.0
Delta ambulatory time before/after self-admin	2.2	2.4	3.6	1.8	-1.3	1.2	-1.6	1.4	1.9
Time in closed arm before self-admin	0.4	0.5	1.5	-0.6	0.3	-0.4	0.6	-0.5	-1.2
Time in closed arm after self-admin	0.6	0.6	1.1	0.6	-1.0	0.2	-0.9	0.8	0.7
Time in open arm before self-admin	1.7	1.8	3.3	1.2	-1.0	1.4	-1.2	1.2	1.8
Time in open arm after self-admin	0.3	0.3	1.5	0.5	0.0	1.2	-0.0	0.2	0.3
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	-0.1	0.2	0.1	-0.1	-0.0	0.3
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.1	-1.0	1.1	0.5	0.9	-0.8	-1.0
Time to tail flick, vehicle, after self-admin	0.5	0.6	0.8	0.7	-0.9	0.4	-0.9	0.7	0.7
Time to tail flick, test, before self-admin	0.5	0.5	1.2	-0.4	1.1	0.2	0.6	-0.6	-0.9
Time to tail flick, test, after self-admin	0.2	0.2	0.6	-0.3	0.8	0.1	0.5	-0.5	-0.4
Delta time to tail flick, vehicle, before/after SA	0.8	0.8	1.1	1.0	-1.1	0.3	-0.9	0.8	1.0
Delta time to tail flick, test, before/after SA	0.1	0.1	0.2	-0.4	0.3	-0.1	0.4	-0.3	-0.2
Ambulatory time before self-admin	0.6	0.7	1.0	0.5	-1.0	0.9	-0.8	0.9	0.6
Ambulatory time after self-admin	7.0	7.7	9.3	2.8	-2.8	2.4	-2.8	2.9	3.0
Total heroin consumption	1.2	1.5	2.2	0.9	-1.2	1.3	-1.1	1.5	1.2
Area under the delay curve	1.0	1.1	1.6	1.1	-1.2	-0.1	-1.2	1.1	1.1
Delay disc. indifference point, 0s delay	1.0	1.1	1.6	0.9	-1.1	0.6	-1.2	1.3	0.9
Delay disc. indifference point, 16s delay	3.1	3.2	4.2	1.8	-2.0	0.9	-2.1	1.9	1.7
Delay disc. indifference point, 2s delay	1.4	1.5	2.1	1.3	-1.4	-0.2	-1.5	1.2	1.3
Delay disc. indifference point, 24s delay	2.6	2.5	3.0	1.7	-1.5	1.1	-1.6	1.7	1.7
Delay disc. indifference point, 4s delay	0.2	0.3	0.4	0.6	-0.7	0.2	-0.6	0.6	0.3
Delay disc. indifference point, 8s delay	0.2	0.2	1.2	0.2	-0.2	-1.1	-0.2	-0.1	0.4
Delay discount exponential model param	1.0	1.1	1.5	-1.2	1.2	0.0	1.2	-1.1	-1.1
Delay discount hyperbolic model param	0.9	1.0	1.3	-1.1	1.1	0.1	1.1	-1.0	-1.0
Fecal boli incidents, locomotor time 1	1.7	1.8	3.2	-1.5	1.1	-1.8	1.1	-1.3	-1.0
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.4	-0.2	0.5	-0.2	0.2	0.2
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	-0.0	0.2	-0.1	0.1	-0.2	-0.2
Bouts of movement, locomotor time 1	2.2	2.4	3.7	1.5	-1.9	0.5	-1.9	1.5	1.5
Total resting periods, locomotor time 1	2.0	2.3	3.5	1.4	-1.8	0.3	-1.9	1.5	1.6
Rest time, locomotor task time 1	0.1	0.1	0.3	-0.6	0.2	-0.2	0.2	-0.1	-0.3
Distance moved, locomotor task time 1	0.1	0.1	0.2	-0.0	0.4	0.5	0.3	-0.4	-0.3
Vertical activity count, locomotor time 1	0.9	1.0	1.9	1.2	-0.7	1.4	-0.8	0.9	0.9
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.6	-0.5	0.4	0.2	0.4	-0.1	-0.8
Bouts of movement, locomotor time 2	0.3	0.3	0.5	0.5	-0.5	-0.6	-0.7	0.3	0.4
Total resting periods, locomotor time 2	0.1	0.1	0.4	0.3	-0.3	-0.7	-0.5	0.1	0.2
Rest time, locomotor task time 2	0.1	0.1	0.3	-0.1	-0.1	0.5	-0.0	0.3	-0.2
Distance moved, locomotor task time 2	0.2	0.3	0.5	-0.3	0.6	-0.1	0.6	-0.5	-0.7
Vertical activity count, locomotor time 2	0.5	0.5	0.7	0.8	-0.7	0.5	-0.7	0.8	0.6
Weight adjusted by age	0.2	0.3	0.4	-0.3	0.7	-0.4	0.6	-0.6	-0.5
Seeking ratio, delayed vs. immediate footshock	1.7	1.9	2.3	1.4	-1.4	1.3	-1.4	1.5	1.2
Locomotion in novel chamber	0.1	0.1	0.4	-0.5	0.1	-0.6	0.2	-0.1	-0.0
Locomotion in novel chamber post-restriction	0.4	0.5	0.8	0.4	-0.8	-0.1	-0.9	0.7	0.9
Progressive ratio	0.1	0.1	0.5	-0.3	0.1	-0.7	0.2	-0.0	0.1
Food seeking constrained by brief footshock	3.6	4.4	5.2	2.0	-2.1	1.9	-2.1	2.3	2.2
Seeking ratio, punishment vs. effort	1.3	1.6	2.3	1.3	-1.3	1.5	-1.2	1.2	1.0
Run reversals in cocaine runway, females	0.1	0.1	0.3	-0.0	0.2	-0.6	0.1	-0.2	0.1
Run reversals in cocaine runway, males	1.6	1.5	2.3	-1.1	1.4	-1.1	1.3	-1.5	-0.9
Latency to leave start box in cocaine runway	0.0	0.0	0.1	-0.1	0.3	-0.2	0.1	-0.1	-0.1
Latency to leave start box in cocaine runway, F	0.4	0.4	0.6	-0.4	0.8	-0.7	0.5	-0.7	-0.5
Latency to leave start box in cocaine runway, M	0.2	0.2	0.3	0.4	-0.5	0.4	-0.3	0.5	0.2
Cd content in liver	0.1	0.1	0.5	-0.3	0.2	-0.7	0.3	-0.2	-0.1
Co content in liver	1.4	1.6	2.4	-1.2	1.2	-1.5	1.3	-1.4	-1.0
Cu content in liver	0.8	0.9	1.3	1.0	-0.9	1.1	-0.9	1.0	0.7
Fe content in liver	0.1	0.1	0.4	-0.2	0.1	-0.6	0.2	-0.1	-0.1
K content in liver	0.2	0.2	0.6	0.4	-0.1	0.8	-0.2	0.3	0.2
Mg content in liver	0.2	0.2	0.4	-0.4	0.6	0.2	0.5	-0.5	-0.6
Mn content in liver	0.7	0.8	1.0	-0.8	1.0	0.8	0.9	-0.6	-1.0
Na content in liver	3.6	3.8	6.5	2.0	-1.7	2.5	-1.8	1.9	1.5
Rb content in liver	0.0	0.0	0.0	0.2	-0.2	-0.0	-0.2	0.1	-0.0
Se content in liver	7.3	8.9	10.8	-3.1	3.3	-1.8	3.2	-2.9	-3.2
Sr content in liver	1.1	1.0	1.1	-1.1	1.0	-0.8	1.0	-1.0	-0.9
Zn content in liver	0.2	0.3	0.3	-0.4	0.5	-0.6	0.6	-0.6	-0.5