RT1-S2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000029001 0.48 0.11 0.0e+00 0.52 0.47 0.54 0.49 9.3e-67 3.2e-58 2.0e-70 1.8e-61
2 BLA gene expression ENSRNOG00000029001 0.75 0.08 0.0e+00 0.58 0.61 0.62 0.63 1.9e-37 9.3e-41 1.0e-41 4.4e-43
3 Brain gene expression ENSRNOG00000029001 0.49 0.04 0.0e+00 0.62 0.65 0.66 0.65 5.1e-72 8.0e-80 2.3e-80 2.5e-79
4 Eye gene expression ENSRNOG00000029001 0.52 0.19 1.9e-04 0.09 0.05 0.1 0.03 1.7e-02 5.7e-02 1.2e-02 1.1e-01
5 IL gene expression ENSRNOG00000029001 0.53 0.16 1.5e-10 0.35 0.32 0.34 0.35 2.7e-09 1.8e-08 6.4e-09 3.8e-09
6 LHb gene expression ENSRNOG00000029001 0.6 0.16 1.4e-13 0.51 0.43 0.46 0.49 4.8e-14 1.9e-11 2.0e-12 2.4e-13
7 Liver gene expression ENSRNOG00000029001 0.14 0.09 2.4e-15 0.14 0.12 0.1 0.13 5.2e-15 3.8e-13 2.0e-11 1.7e-14
8 NAcc gene expression ENSRNOG00000029001 0.62 0.11 0.0e+00 0.47 0.4 0.54 0.36 5.4e-39 3.2e-31 7.9e-48 1.5e-27
9 OFC gene expression ENSRNOG00000029001 0.63 0.14 2.1e-13 0.28 0.37 0.27 0.3 2.1e-07 9.8e-10 3.6e-07 6.5e-08
10 PL gene expression ENSRNOG00000029001 0.77 0.05 0.0e+00 0.65 0.48 0.66 0.23 7.9e-65 5.8e-41 5.9e-67 2.3e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.96.17.62.72.62.80.42.52.52.42.72.62.6
BMI without tail3.87.99.42.83.03.01.13.03.13.02.73.02.9
Body weight6.828.934.05.25.85.82.95.75.75.74.95.75.8
Epididymis fat weight2.66.020.13.21.41.8-4.51.51.51.43.71.71.2
Glucose1.32.09.2-1.8-0.5-0.93.0-0.5-0.5-0.5-2.1-0.8-0.5
Heart weight0.10.10.20.30.30.40.40.30.30.30.30.40.5
Left kidney weight4.211.914.23.43.63.71.73.73.63.53.33.73.8
Right kidney weight3.610.312.42.93.43.52.33.43.43.22.73.43.5
Tail length4.914.817.62.84.13.94.14.14.14.22.44.04.2
Length with tail4.717.321.23.44.54.33.84.44.44.43.14.44.6
Length without tail3.47.59.62.43.02.92.02.82.82.92.32.93.1
Liver weight, left0.60.92.50.41.10.81.61.01.01.00.20.91.1
Liver weight, right3.55.810.71.52.62.33.32.52.52.61.22.42.6
Parametrial fat weight2.24.45.62.32.32.4-0.02.02.02.32.32.22.2
Retroperitoneal fat weight0.51.52.01.31.31.2-0.11.41.41.31.31.21.3
Intraocular pressure1.11.52.5-1.1-1.4-1.2-0.1-1.6-1.6-1.2-1.0-1.2-1.2
Extensor digitorum longus weight0.10.42.3-0.10.50.31.50.50.50.4-0.20.30.5
Soleus weight0.72.113.7-0.31.00.73.71.11.10.9-0.70.81.1
Tibialis anterior weight0.10.32.00.50.00.1-1.40.10.1-0.10.70.0-0.1
Tibia length2.67.411.61.92.92.83.42.82.82.81.72.83.0
Number of licking bursts0.30.30.8-0.8-0.4-0.50.9-0.4-0.4-0.4-0.9-0.5-0.4
Food consumed during 24 hour testing period0.91.02.20.51.11.01.51.11.11.10.41.01.1
Times rat made contact with spout1.41.63.4-0.7-1.3-1.2-1.9-1.4-1.4-1.3-0.5-1.2-1.4
Mean time between licks in bursts0.60.96.3-1.0-0.0-0.32.5-0.1-0.1-0.1-1.2-0.20.1
Mean num. licks in bursts0.30.43.00.4-0.3-0.1-1.7-0.3-0.3-0.30.6-0.1-0.3
Std. dev. time between licks in bursts0.60.75.6-0.60.40.12.40.40.40.4-0.80.10.4
Water consumed over 24 hours0.00.00.2-0.10.10.00.50.00.00.1-0.20.00.1
Indifference point 0 sec0.50.83.01.10.60.5-1.70.50.40.61.20.60.4
Indifference point AUC2.52.93.61.71.91.90.71.71.71.81.61.81.9
Indifference point function ln k0.50.71.0-1.0-0.8-0.70.7-0.8-0.8-0.8-1.0-0.8-0.7
Indifference point function log k0.50.71.0-1.0-0.8-0.70.7-0.8-0.8-0.8-1.0-0.8-0.7
Delay discounting total patch changes 0 sec0.71.13.61.40.80.8-1.90.60.60.81.50.80.6
Delay discounting total patch changes 12 sec0.91.22.51.40.90.9-1.60.80.70.81.50.90.8
Delay discounting total patch changes 18 sec0.50.74.80.90.20.2-2.20.10.10.11.10.20.1
Delay discounting total patch changes 24 sec1.01.28.40.1-0.7-0.9-2.9-0.6-0.6-0.70.3-0.7-0.9
Delay discounting total patch changes 6 sec0.81.24.81.40.70.7-2.20.50.50.71.60.70.5
Delay discounting time to switch 0 sec0.30.52.1-0.3-0.6-0.6-1.5-0.6-0.6-0.6-0.1-0.7-0.7
Delay discounting water rate 0 sec0.40.60.80.90.70.9-0.10.70.70.60.90.90.8
Delay discounting water rate 12 sec0.20.31.10.0-0.4-0.4-1.0-0.8-0.8-0.50.2-0.3-0.3
Delay discounting water rate 18 sec0.20.30.40.60.50.50.30.50.50.60.40.60.6
Delay discounting water rate 24 sec1.52.13.01.61.51.70.51.41.41.31.61.61.6
Delay discounting water rate 6 sec0.10.10.40.3-0.20.0-0.6-0.3-0.3-0.20.30.1-0.1
Locomotor activity1.32.16.80.51.41.22.61.51.51.60.21.31.4
Locomotor testing distance0.20.31.00.10.50.41.00.50.50.6-0.00.40.4
Locomotor testing rearing0.50.82.30.40.90.81.50.90.91.10.30.80.9
Light reinforcement 10.10.20.60.60.20.2-0.80.10.10.10.70.30.2
Light reinforcement 20.70.91.20.81.10.91.11.01.00.90.71.01.1
Reaction time number correct0.20.32.00.6-0.00.3-1.40.00.1-0.10.80.2-0.0
Reaction time mean minus median1.01.39.3-1.10.1-0.33.00.20.20.1-1.4-0.20.2
Reaction time mean minus median AUC0.81.05.9-1.1-0.2-0.52.4-0.2-0.2-0.3-1.4-0.4-0.1
Reaction time num false alarms0.30.50.70.60.60.80.60.70.70.60.60.80.8
Reaction time num false alarms AUC0.60.81.10.90.91.00.61.00.90.90.81.11.0
Reaction time trials correct on left0.20.32.00.6-0.00.3-1.40.00.1-0.10.80.2-0.0
Reaction time trials on left0.20.31.70.60.00.3-1.30.10.1-0.00.80.20.0
Reaction time mean1.01.36.3-1.4-0.5-0.82.5-0.4-0.4-0.4-1.6-0.6-0.4
Reaction time mean AUC1.01.36.5-1.4-0.5-0.82.6-0.4-0.4-0.4-1.6-0.6-0.4
Median of all reaction times0.70.93.5-1.2-0.6-0.71.9-0.6-0.6-0.4-1.4-0.6-0.5
Reaction time omissions0.70.95.3-1.1-0.2-0.52.3-0.1-0.2-0.2-1.3-0.4-0.1
Reaction time false alarm rate0.40.61.70.40.70.71.30.80.70.70.20.80.8
Reaction time premature initiation rate1.41.92.61.51.51.40.21.61.61.31.41.41.4
Reaction time premature initiations1.72.43.51.91.61.7-0.51.71.71.41.91.61.5
Std. dev. reaction times0.91.39.7-1.00.2-0.23.10.30.30.2-1.3-0.10.3
Reaction time trials completed0.20.31.70.60.00.3-1.30.10.1-0.00.80.20.0
Reaction time trials AUC0.20.31.70.6-0.00.2-1.3-0.00.0-0.10.70.1-0.0
Social response proportion0.10.10.5-0.00.30.20.70.40.40.2-0.10.20.3
Social responses0.10.20.20.40.40.50.10.40.40.30.40.50.4
Social time0.60.85.7-0.50.40.12.40.50.50.4-0.80.20.4
Conditioned locomotion0.70.91.20.71.00.90.81.11.11.00.60.91.0
Cocaine response after cond. corrected0.50.50.7-0.7-0.8-0.8-0.4-0.8-0.8-0.8-0.6-0.8-0.8
Cocaine response after cond. not corrected0.20.20.90.10.40.30.90.40.40.4-0.00.30.5
Cocaine response before conditioning4.96.07.42.02.72.62.22.62.62.71.72.62.7
Saline control response1.21.52.91.61.21.2-1.01.11.11.11.71.21.1
Condit. Reinf. active minus inactive responses1.41.72.11.21.41.40.81.31.31.41.11.41.4
Condit. Reinf. active-inactive response ratio3.03.13.81.51.91.91.31.91.91.91.41.91.9
Condit. Reinf. active responses0.00.00.0-0.00.0-0.00.2-0.1-0.1-0.0-0.00.00.1
Condit. Reinf. inactive responses1.72.22.7-1.4-1.6-1.6-0.6-1.6-1.6-1.6-1.3-1.5-1.5
Condit. Reinf. lever presses0.40.60.9-0.7-0.8-0.8-0.2-0.9-0.9-0.9-0.7-0.8-0.8
Condit. Reinf. lever reinforcers received0.00.10.1-0.2-0.2-0.20.3-0.3-0.3-0.2-0.3-0.2-0.1
Pavlov. Cond. lever latency0.30.40.60.50.70.60.40.70.70.70.40.60.6
Pavlov. Cond. magazine entry latency0.60.70.90.70.90.90.80.90.90.90.60.90.9
Pavlov. Cond. change in total contacts0.20.20.50.70.40.5-0.30.40.40.40.70.50.4
Pavlov. Cond. index score0.00.00.00.10.10.10.1-0.0-0.00.10.10.10.1
Pavlov. Cond. latency score0.10.10.10.30.30.3-0.00.20.20.20.30.30.3
Pavlov. Cond. lever contacts0.20.20.8-0.0-0.4-0.3-0.9-0.5-0.5-0.50.1-0.3-0.4
Pavlov. Cond. magazine entry number0.30.40.5-0.7-0.7-0.7-0.2-0.7-0.7-0.7-0.6-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.51.93.4-1.7-1.3-1.41.2-1.3-1.3-1.2-1.8-1.3-1.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.10.10.10.10.00.00.10.10.10.1
Pavlov. Cond. response bias0.10.10.1-0.2-0.3-0.3-0.3-0.4-0.4-0.3-0.1-0.3-0.3
Conditioned reinforcement - actives0.50.50.80.70.60.60.10.90.90.90.60.60.5
Conditioned reinforcement - inactives1.51.72.41.41.31.1-1.01.51.61.51.31.11.0
Conditioned locomotion0.00.00.30.10.10.10.60.10.20.2-0.10.1-0.0
Intermittent access intake day 1-15 change0.70.70.90.81.01.00.60.80.90.80.80.90.9
Intermittent access intake escalation0.40.41.50.30.60.61.20.50.60.50.20.60.6
Intermittent access intake escalation 20.70.76.1-0.50.30.12.5-0.00.0-0.0-0.70.20.3
Intermitt. access day 1 inactive lever presses0.20.21.00.10.40.41.00.30.30.30.00.40.5
Intermitt. access day 15 inactive lever presses2.52.83.31.81.81.8-0.01.71.71.81.71.81.8
Intermitt. access escalation Index3.43.14.1-1.8-1.8-1.9-0.2-1.8-1.7-2.0-1.8-1.9-1.8
Intermittent access day 1 total infusions0.50.61.5-0.5-0.8-0.9-1.2-0.7-0.7-0.5-0.5-0.8-0.9
Intermittent access day 15 total infusions0.10.10.2-0.1-0.2-0.3-0.5-0.1-0.1-0.0-0.2-0.3-0.4
Intermittent access terminal intake (last 3 days)0.10.10.20.30.30.2-0.40.20.30.40.30.20.1
Intermittent access total infusions0.00.00.30.1-0.2-0.2-0.5-0.1-0.10.1-0.0-0.1-0.3
Intermittent access day 1 locomotion0.20.20.4-0.5-0.3-0.7-0.1-0.1-0.0-0.1-0.7-0.5-0.4
Intermittent access day 15 total locomotion0.91.01.60.61.00.91.31.01.11.20.51.01.0
Intermittent access total locomotion0.50.61.10.50.70.71.00.70.81.00.30.80.7
Intermittent access standard deviation2.42.63.41.81.71.8-0.11.51.61.51.81.71.7
Cocaine induced anxiety2.62.94.5-2.1-1.6-1.80.7-1.8-1.7-1.7-2.1-1.7-1.6
Post-drug Anxiety1.11.21.6-1.3-1.1-1.00.9-1.2-1.2-1.1-1.2-1.0-0.9
Baseline Anxiety0.10.10.30.40.00.2-0.30.0-0.0-0.00.60.10.1
Lifetime Intake0.00.00.20.1-0.1-0.1-0.5-0.10.00.20.0-0.1-0.2
Incentive Sensitization - Responses0.60.60.8-0.8-0.9-0.9-0.3-0.7-0.7-0.8-0.7-0.9-0.8
Incentive Sensitization - Breakpoint0.80.81.0-0.9-1.0-1.0-0.2-0.8-0.9-1.0-0.8-1.0-0.9
Progressive ratio test 1 active lever presses0.20.20.9-0.3-0.4-0.5-0.9-0.2-0.2-0.0-0.4-0.5-0.5
Progressive ratio test 1 breakpoint0.20.21.1-0.2-0.4-0.5-1.1-0.3-0.3-0.1-0.3-0.5-0.5
Progressive ratio test 1 inactive lever presses0.10.11.20.2-0.1-0.1-1.1-0.1-0.10.00.3-0.1-0.2
Progressive ratio test 2 active lever presses0.60.60.9-0.7-1.0-0.9-0.7-0.7-0.7-0.5-0.7-0.9-1.0
Progressive ratio test 2 breakpoint1.01.11.6-1.0-1.3-1.2-0.8-1.0-1.1-0.8-0.9-1.2-1.3
Progressive ratio test 2 inactive lever presses0.30.40.90.60.70.60.10.70.70.90.40.60.6
Total sessions with >9 infusions0.10.10.30.30.20.1-0.20.50.50.50.10.20.1
Short access day 1 total inactive lever presses0.30.42.6-0.20.40.21.60.30.40.4-0.30.30.4
Short access day 10 total inactive lever presses0.20.21.6-0.20.10.01.3-0.00.0-0.3-0.30.10.2
Short access day 1 total infusions0.30.30.6-0.6-0.7-0.7-0.3-0.5-0.3-0.5-0.6-0.7-0.7
Short access day 10 total infusions0.10.10.40.40.20.2-0.20.30.40.60.30.30.2
Short access total infusions0.10.10.30.40.20.2-0.30.20.20.60.30.20.1
Short access day 1 locomotion3.63.84.7-2.0-2.1-2.2-0.2-2.1-2.2-1.8-1.9-2.1-2.1
Short access day 10 total locomotion0.40.43.5-0.20.00.21.90.0-0.00.2-0.30.20.3
Short access total locomotion0.20.20.3-0.4-0.4-0.40.4-0.6-0.5-0.1-0.5-0.4-0.4
Compulsive drug intake3.33.33.9-2.0-1.9-2.0-0.2-1.9-1.8-1.9-2.0-2.0-1.9
One hour access (0.3 mA shock)0.60.71.0-0.8-0.9-1.0-0.4-0.7-0.6-0.6-1.0-0.9-1.0
One hour access (shock baseline)0.60.71.20.70.90.80.40.90.91.10.50.80.8
Number of responses in last shaping day0.20.20.60.30.50.40.30.60.70.80.30.50.4
Context. condit. distance diff. score5.87.111.3-3.3-2.6-2.81.2-2.6-2.6-2.5-3.4-2.7-2.5
Locomotion velocity, session 10.20.20.5-0.6-0.3-0.40.3-0.3-0.3-0.3-0.7-0.4-0.4
Locomotion distance, session 10.40.51.6-0.3-0.8-0.7-1.3-0.8-0.8-0.6-0.1-0.7-0.7
Locomotion velocity, session 20.00.00.1-0.20.00.00.30.00.00.1-0.3-0.00.0
Locomotion distance, session 20.30.40.5-0.6-0.7-0.7-0.6-0.7-0.7-0.7-0.5-0.7-0.7
Locomotion velocity, session 30.10.10.90.40.10.2-1.00.10.10.10.50.20.0
Locomotion distance, session 31.71.82.3-1.3-1.4-1.4-0.8-1.3-1.3-1.5-1.2-1.4-1.5
Stereotopy head waving bouts, day 31.82.12.61.11.61.51.41.61.61.60.91.51.6
Stereotopy head waving duration, day 31.31.62.01.01.41.31.01.41.41.40.81.31.4
Locomotion velocity, session 74.55.05.9-2.3-2.3-2.4-0.5-2.4-2.4-2.3-2.2-2.4-2.4
Locomotion distance, session 74.35.56.6-2.2-2.5-2.5-1.3-2.4-2.4-2.6-2.1-2.5-2.6
Stereotopy head waving bouts, day 72.12.42.91.51.71.70.51.61.61.71.51.61.6
Stereotopy head waving duration, day 72.93.54.41.82.02.01.02.02.02.11.72.02.0
Locomotion velocity, session 80.60.85.3-0.90.2-0.02.30.00.00.2-1.2-0.10.2
Locomotion distance, session 83.14.67.2-2.6-2.1-2.30.7-2.1-2.1-2.0-2.7-2.2-2.1
Degree of sensitization distance0.40.40.8-0.8-0.5-0.60.7-0.5-0.5-0.5-0.9-0.5-0.4
Degree of sensitization stereotypy1.41.51.81.21.31.30.41.31.31.31.21.31.3
Condit. Reinf. active minus inactive responses0.80.91.1-1.0-1.0-1.0-0.2-1.0-1.0-1.0-1.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.00.10.40.2-0.00.0-0.60.10.10.00.30.0-0.0
Condit. Reinf. active responses1.31.61.9-1.3-1.4-1.4-0.5-1.4-1.4-1.3-1.2-1.4-1.3
Condit. Reinf. inactive responses2.32.73.4-1.4-1.8-1.7-1.2-1.9-1.9-1.8-1.2-1.7-1.7
Incentive salience index mean1.51.82.9-1.7-1.3-1.40.7-1.3-1.3-1.2-1.7-1.4-1.2
Condit. Reinf. lever presses2.53.45.5-2.3-1.7-1.91.0-1.8-1.8-1.7-2.4-1.9-1.7
Time in familiar zone, hab. session 13.53.34.1-1.2-2.0-1.8-1.9-2.0-2.0-2.0-1.0-1.8-2.0
Time in novel zone, hab. session 11.71.72.50.71.41.31.61.41.41.50.51.31.4
Total zone transitions, hab. session 10.60.91.1-0.9-1.0-1.0-0.5-1.1-1.1-1.0-0.8-1.0-1.0
Total locomotion distance, hab. session 10.50.81.0-0.8-1.0-0.9-0.7-0.9-0.9-1.0-0.7-0.9-1.0
Locomotion velocity, hab. session 10.20.30.6-0.3-0.7-0.6-0.8-0.6-0.6-0.7-0.3-0.6-0.6
Time in familiar zone, hab. session 20.30.30.4-0.3-0.6-0.6-0.6-0.7-0.7-0.6-0.2-0.5-0.6
Time in novel zone, hab. session 20.30.30.50.50.70.60.10.70.70.60.40.60.6
Total zone transitions, hab. session 20.00.10.40.2-0.1-0.1-0.6-0.2-0.2-0.10.3-0.0-0.1
Total locomotion distance, hab. session 21.11.51.9-1.0-1.4-1.3-0.9-1.3-1.3-1.4-0.9-1.3-1.3
Locomotion velocity, hab. session 21.21.62.1-1.1-1.4-1.4-0.8-1.3-1.3-1.4-1.0-1.3-1.4
Novel to familiar place preference ratio0.10.10.40.20.00.1-0.60.00.00.00.30.0-0.0
Novelty place preference0.10.10.20.40.30.3-0.40.30.30.30.40.30.2
Time in novel zone, NPP test0.20.20.30.50.40.4-0.30.50.50.40.50.40.4
Total zone transitions, NPP test1.21.71.9-1.3-1.4-1.4-0.4-1.4-1.4-1.4-1.2-1.4-1.4
Total locomotion distance, NPP test1.21.72.2-1.1-1.4-1.3-1.0-1.3-1.3-1.5-1.0-1.4-1.4
Locomotion velocity, NPP test2.02.93.7-1.5-1.9-1.8-1.3-1.7-1.7-1.9-1.3-1.8-1.9
Pavlov. Cond. lever latency1.01.33.51.50.71.0-1.90.80.80.71.70.90.6
Pavlov. Cond. magazine entry latency1.21.63.4-1.6-0.8-1.11.7-1.1-1.1-0.9-1.8-1.0-0.8
Pavlov. Cond. change in total contacts0.60.72.80.20.80.61.70.60.60.8-0.00.70.9
Pavlov. Cond. index score1.41.84.4-1.8-0.8-1.12.1-1.0-1.0-0.9-2.0-1.1-0.8
Pavlov. Cond. latency score1.01.24.6-1.4-0.5-0.82.1-0.7-0.7-0.5-1.7-0.7-0.5
Pavlov. Cond. lever contacts0.60.74.1-1.0-0.2-0.52.0-0.3-0.3-0.2-1.2-0.4-0.1
Pavlov. Cond. magazine entry number1.82.24.01.91.31.5-1.21.51.51.32.01.41.2
Pavlov. Cond. intertrial magazine entries0.50.62.6-0.1-0.8-0.7-1.6-0.7-0.7-0.80.1-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.1.62.04.2-1.8-1.0-1.22.0-1.2-1.2-1.0-2.0-1.2-0.9
Pavlov. Cond. response bias1.82.14.2-1.9-1.1-1.31.9-1.3-1.3-1.1-2.1-1.3-1.0
Bone: apparent density1.52.42.9-1.2-1.7-1.6-1.4-1.7-1.7-1.7-1.1-1.6-1.7
Bone surface0.20.30.70.30.50.50.80.50.50.60.20.50.6
Bone volume0.10.10.20.40.30.3-0.10.30.30.30.40.30.3
Bone: connectivity density2.84.35.1-2.1-2.2-2.3-0.7-2.2-2.2-2.2-2.0-2.2-2.2
Bone: cortical apparent density0.60.82.21.20.60.7-1.50.60.60.61.40.70.5
Bone: cortical area2.53.74.31.92.02.10.62.02.02.11.92.02.0
Bone: cortical porosity0.50.60.90.90.80.8-0.40.70.70.71.00.80.7
Bone: cortical porosity0.70.70.90.80.90.90.60.90.90.90.70.90.9
Bone: cortical thickness3.45.69.52.92.22.4-1.62.22.22.23.12.32.1
Bone: cortical thickness0.81.02.71.30.70.8-1.70.70.70.61.50.70.6
Bone: cortical tissue density0.50.61.81.10.50.6-1.30.50.50.51.20.60.5
Bone: elastic displacement0.20.20.80.50.20.3-0.90.20.20.10.60.30.2
Bone: elastic work1.92.53.21.81.61.7-0.11.71.71.61.71.71.6
Bone: endosteal estimation2.65.515.81.02.42.14.02.42.42.40.62.22.5
Bone: endosteal perimeter0.71.411.0-0.80.50.23.30.50.50.5-1.10.30.6
Bone: final force6.410.513.03.63.43.5-0.13.33.33.43.63.43.3
Bone: final moment5.89.611.63.43.23.30.13.23.23.33.43.33.2
Bone: marrow area2.55.515.51.02.42.13.92.32.32.40.62.22.5
Bone: maximum diameter0.81.56.80.21.10.92.61.11.11.1-0.00.91.2
Bone: maximum force5.49.511.03.33.23.30.23.23.23.33.33.23.2
Bone: maximum moment5.08.710.03.13.13.20.43.13.13.23.13.13.1
Bone: minimum diameter0.91.77.70.21.21.02.81.21.21.2-0.01.01.3
Bone: periosteal estimation3.16.27.61.82.72.52.82.72.72.71.52.62.7
Bone: periosteal perimeter1.32.25.00.81.61.42.21.51.51.60.51.41.6
Bone: post-yield work0.20.32.4-0.60.1-0.11.50.00.00.1-0.7-0.00.1
Bone: stiffness1.32.02.91.71.51.5-0.41.41.41.51.71.51.4
Bone: tissue strength4.64.55.32.32.22.3-0.02.22.22.22.32.22.2
Bone: trabecular number1.62.43.0-1.2-1.7-1.6-1.7-1.7-1.7-1.6-1.0-1.6-1.7
Bone: trabecular spacing4.25.46.42.12.52.51.72.52.52.51.92.52.5
Bone: trabecular thickness1.21.51.8-1.0-1.3-1.3-1.1-1.3-1.3-1.3-0.8-1.3-1.3
Bone: trabecular tissue density2.02.73.31.81.71.80.51.71.71.71.71.81.8
Breakpoint value in progressive ratio session1.11.21.6-1.1-1.1-1.2-0.3-1.3-1.2-1.0-1.1-1.2-1.2
Distance traveled before self-admin0.10.11.0-0.30.00.01.0-0.00.00.0-0.4-0.00.0
Distance traveled after self-admin0.20.30.90.20.50.50.90.30.30.50.30.50.6
Delta time in closed arm before/after self-admin0.20.20.20.40.40.5-0.00.40.30.50.40.40.4
Delta time in open arm before/after self-admin0.00.00.10.20.00.1-0.3-0.2-0.1-0.00.30.10.1
Diff in mean of infusions in LGA sessions3.84.25.5-2.0-2.2-2.2-1.3-2.1-2.0-2.3-1.7-2.2-2.3
Extinction: sum of active levers before priming0.60.60.8-0.6-0.7-0.8-0.9-0.8-0.8-0.7-0.5-0.8-0.8
Active lever presses in extinction session 60.10.10.70.1-0.2-0.2-0.8-0.5-0.4-0.30.1-0.2-0.2
Delta distance traveled before/after self-admin1.01.11.61.11.11.10.11.01.01.01.21.21.2
Delta ambulatory time before/after self-admin0.40.40.50.50.70.60.50.70.60.50.60.70.7
Time in closed arm before self-admin0.00.00.1-0.1-0.2-0.1-0.1-0.2-0.2-0.3-0.0-0.1-0.1
Time in closed arm after self-admin0.80.81.41.10.80.9-0.60.80.80.81.20.90.8
Time in open arm before self-admin0.20.30.8-0.6-0.2-0.60.8-0.1-0.1-0.2-0.9-0.4-0.3
Time in open arm after self-admin0.70.81.3-1.0-0.7-1.10.4-0.9-0.9-0.8-1.1-0.9-0.7
Sum of active levers in priming session hrs 5-60.50.50.8-0.6-0.6-0.8-0.5-0.8-0.8-0.9-0.6-0.8-0.7
Time to tail flick, vehicle, before self-admin0.10.10.4-0.5-0.1-0.30.6-0.2-0.2-0.1-0.5-0.3-0.2
Time to tail flick, vehicle, after self-admin0.90.91.7-1.3-0.9-0.91.3-0.7-0.8-0.6-1.3-0.8-0.8
Time to tail flick, test, before self-admin0.10.10.10.30.30.1-0.20.20.20.30.30.20.2
Time to tail flick, test, after self-admin1.01.01.9-1.3-0.9-1.10.8-0.7-0.7-1.0-1.4-1.0-0.9
Delta time to tail flick, vehicle, before/after SA0.70.71.0-0.9-1.0-0.9-0.1-0.8-0.9-0.8-0.9-0.9-0.9
Delta time to tail flick, test, before/after SA1.11.01.4-1.1-1.1-1.0-0.2-0.9-0.9-1.2-1.0-1.0-1.0
Ambulatory time before self-admin0.00.00.00.00.20.2-0.20.20.20.0-0.00.10.1
Ambulatory time after self-admin0.10.20.80.10.40.30.90.20.20.20.10.40.5
Total heroin consumption0.00.00.3-0.1-0.0-0.1-0.5-0.0-0.1-0.2-0.2-0.1-0.1
Area under the delay curve2.22.43.11.71.61.5-0.01.81.81.61.71.61.5
Delay disc. indifference point, 0s delay0.60.61.00.60.70.71.01.01.00.80.50.70.8
Delay disc. indifference point, 16s delay1.71.73.21.61.11.1-1.71.21.21.11.81.11.0
Delay disc. indifference point, 2s delay2.42.63.81.41.61.61.02.02.01.71.31.61.7
Delay disc. indifference point, 24s delay0.50.50.90.90.70.6-0.50.70.70.70.90.70.6
Delay disc. indifference point, 4s delay3.43.55.11.62.01.81.42.32.31.91.51.92.0
Delay disc. indifference point, 8s delay0.40.40.60.70.60.5-0.10.70.70.70.70.60.6
Delay discount exponential model param2.12.33.1-1.6-1.5-1.40.0-1.8-1.8-1.6-1.6-1.5-1.5
Delay discount hyperbolic model param2.32.43.4-1.6-1.6-1.5-0.3-1.8-1.8-1.6-1.6-1.6-1.6
Fecal boli incidents, locomotor time 10.90.91.2-1.0-1.1-1.0-0.4-1.0-1.0-1.0-1.0-1.0-1.1
Change in fecal boli incidents, locomotor task0.50.50.70.60.80.80.40.60.60.70.80.80.9
Time >=10cm from walls, locomotor time 10.50.52.10.30.60.81.50.40.40.80.10.70.6
Bouts of movement, locomotor time 11.21.32.0-1.3-1.2-1.20.8-1.2-1.2-1.1-1.4-1.1-1.0
Total resting periods, locomotor time 10.60.71.1-1.0-0.8-0.90.7-0.9-0.9-0.7-1.0-0.7-0.6
Rest time, locomotor task time 10.20.21.7-0.4-0.0-0.11.3-0.2-0.20.1-0.50.00.2
Distance moved, locomotor task time 10.70.81.21.00.90.9-0.51.01.00.81.10.80.7
Vertical activity count, locomotor time 10.40.40.70.70.50.8-0.70.80.80.40.70.50.4
Time >=10cm from walls, locomotor time 20.20.21.5-0.10.10.31.20.30.30.2-0.30.10.1
Bouts of movement, locomotor time 20.91.03.50.20.90.71.91.11.10.9-0.10.80.9
Total resting periods, locomotor time 20.70.84.5-0.10.60.52.10.90.90.6-0.40.50.7
Rest time, locomotor task time 20.80.96.0-1.1-0.3-0.32.5-0.4-0.4-0.3-1.2-0.3-0.1
Distance moved, locomotor task time 20.80.92.11.20.70.8-1.51.01.00.61.30.70.5
Vertical activity count, locomotor time 20.20.21.60.4-0.10.2-1.30.10.1-0.00.50.1-0.1
Weight adjusted by age3.64.05.51.92.32.01.42.02.02.21.62.22.3
Seeking ratio, delayed vs. immediate footshock0.50.50.90.80.80.8-0.50.60.60.90.60.80.7
Locomotion in novel chamber0.70.91.30.91.00.9-0.11.11.10.80.91.01.1
Locomotion in novel chamber post-restriction0.60.71.11.00.80.9-0.00.90.90.81.10.90.9
Progressive ratio5.36.18.02.52.62.50.52.82.82.62.42.52.5
Food seeking constrained by brief footshock0.00.00.0-0.1-0.0-0.20.10.10.1-0.1-0.2-0.2-0.1
Seeking ratio, punishment vs. effort4.55.66.9-2.4-2.4-2.4-0.4-2.6-2.6-2.6-2.4-2.5-2.4
Run reversals in cocaine runway, females0.30.21.50.60.10.2-1.2-0.0-0.00.10.70.20.1
Run reversals in cocaine runway, males1.21.15.10.21.00.72.31.01.00.9-0.20.81.0
Latency to leave start box in cocaine runway0.10.10.20.20.20.1-0.40.20.20.30.20.20.2
Latency to leave start box in cocaine runway, F0.20.20.4-0.5-0.5-0.6-0.3-0.4-0.4-0.3-0.6-0.5-0.6
Latency to leave start box in cocaine runway, M1.31.32.11.41.21.2-0.50.90.91.01.41.31.2
Cd content in liver0.50.61.11.00.70.7-0.80.60.60.61.00.70.6
Co content in liver1.41.62.91.61.21.2-0.81.21.21.21.71.21.2
Cu content in liver3.54.25.2-1.5-2.2-2.1-2.3-2.2-2.2-2.2-1.2-2.1-2.2
Fe content in liver0.40.50.90.90.60.7-1.00.60.60.61.00.70.5
K content in liver0.10.10.2-0.4-0.4-0.40.2-0.4-0.4-0.3-0.3-0.4-0.4
Mg content in liver2.42.43.7-1.9-1.4-1.61.4-1.5-1.5-1.4-1.9-1.5-1.3
Mn content in liver1.61.96.0-1.8-0.8-1.02.5-0.8-0.8-0.8-2.0-1.0-0.7
Na content in liver0.10.10.20.40.20.3-0.30.20.20.20.40.20.2
Rb content in liver1.01.31.5-1.1-1.2-1.2-0.5-1.2-1.2-1.2-1.1-1.2-1.2
Se content in liver1.41.66.3-1.6-0.7-1.02.5-0.8-0.8-0.8-1.8-0.9-0.6
Sr content in liver0.60.50.70.50.80.70.80.80.80.80.40.80.8
Zn content in liver0.00.00.3-0.2-0.0-0.10.60.00.0-0.0-0.2-0.10.0