Hub : Genes

Siva1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000028640 0.05 0.03 2.2e-06 0.03 0.04 0.03 0.03 3.8e-04 4.1e-05 4.1e-04 6.3e-04
2 BLA gene expression ENSRNOG00000028640 0.05 0.04 3.4e-03 0.05 0.04 0.04 0.04 1.1e-03 3.0e-03 3.9e-03 2.6e-03
3 Brain gene expression ENSRNOG00000028640 0.12 0.11 6.3e-09 0.07 0.06 0.08 0.08 2.6e-07 6.5e-06 1.1e-07 8.9e-08
4 IL gene expression ENSRNOG00000028640 0.14 0.13 9.4e-03 0.09 0.07 0.07 0.08 4.0e-03 1.0e-02 8.7e-03 4.8e-03
5 LHb gene expression ENSRNOG00000028640 0.13 0.11 5.7e-03 0.04 0.06 0.11 0.04 4.1e-02 1.3e-02 1.4e-03 4.6e-02
6 Liver gene expression ENSRNOG00000028640 0.06 0.04 3.0e-07 0.04 0.05 0.04 0.04 2.7e-05 3.2e-06 9.3e-06 1.2e-05
7 PL gene expression ENSRNOG00000028640 0.06 0.04 3.8e-05 0.05 0.05 0.05 0.05 1.8e-04 7.1e-05 1.4e-04 1.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.27.07.7-2.7-2.5-2.7-2.72.4-2.8-2.8
BMI without tail0.61.21.9-1.3-0.3-1.1-1.11.4-1.2-1.1
Body weight0.83.56.32.21.52.00.7-2.52.01.6
Epididymis fat weight3.47.810.2-2.6-3.0-2.7-3.22.3-2.8-2.9
Glucose0.30.51.50.30.90.61.2-0.20.50.6
Heart weight0.00.00.1-0.20.0-0.1-0.10.4-0.10.1
Left kidney weight2.16.08.72.81.92.61.4-2.92.72.4
Right kidney weight1.23.44.52.11.52.00.9-1.92.12.0
Tail length4.814.416.24.03.84.03.1-3.94.03.7
Length with tail7.527.535.85.84.65.54.0-6.05.55.0
Length without tail4.08.714.03.42.13.02.1-3.73.12.7
Liver weight, left2.54.14.82.02.21.92.2-2.02.01.8
Liver weight, right0.10.20.80.60.10.30.1-0.90.40.1
Parametrial fat weight0.00.10.2-0.4-0.2-0.2-0.30.5-0.3-0.3
Retroperitoneal fat weight0.20.50.9-0.6-1.0-0.5-0.90.3-0.7-0.9
Intraocular pressure0.10.10.3-0.4-0.5-0.1-0.30.5-0.3-0.1
Extensor digitorum longus weight8.232.942.76.25.15.84.7-6.56.05.5
Soleus weight0.72.16.91.80.21.3-0.2-2.61.40.7
Tibialis anterior weight0.62.13.91.71.21.41.0-2.01.51.2
Tibia length0.10.41.00.40.80.61.0-0.40.40.4
Number of licking bursts0.30.31.0-0.80.1-0.60.21.0-0.6-0.3
Food consumed during 24 hour testing period0.60.71.51.00.41.00.3-1.20.90.8
Times rat made contact with spout0.20.20.50.40.40.30.7-0.60.30.2
Mean time between licks in bursts0.60.81.4-0.9-0.7-0.8-1.21.2-0.8-0.7
Mean num. licks in bursts0.50.51.70.90.20.70.1-1.30.70.4
Std. dev. time between licks in bursts0.20.21.00.3-0.40.3-1.0-0.40.20.1
Water consumed over 24 hours2.63.04.11.62.01.72.0-1.41.71.8
Indifference point 0 sec5.28.412.03.22.52.92.7-3.53.02.6
Indifference point AUC3.33.97.72.31.61.81.6-2.82.01.4
Indifference point function ln k0.81.22.01.01.11.30.8-0.61.21.4
Indifference point function log k0.81.22.01.01.11.30.8-0.61.21.4
Delay discounting total patch changes 0 sec6.19.914.23.42.63.12.9-3.83.22.8
Delay discounting total patch changes 12 sec4.05.47.02.42.12.22.4-2.62.32.1
Delay discounting total patch changes 18 sec1.92.54.31.71.11.61.6-2.11.51.2
Delay discounting total patch changes 24 sec0.70.82.11.10.50.90.6-1.50.90.6
Delay discounting total patch changes 6 sec3.65.510.62.62.12.12.1-3.32.31.6
Delay discounting time to switch 0 sec11.417.519.2-4.4-4.3-4.0-4.14.2-4.3-3.9
Delay discounting water rate 0 sec18.829.933.65.65.85.25.7-5.25.55.2
Delay discounting water rate 12 sec9.614.419.93.54.53.73.8-3.13.84.0
Delay discounting water rate 18 sec5.06.67.22.52.62.62.6-2.22.62.7
Delay discounting water rate 24 sec3.95.46.42.32.52.32.3-1.92.42.5
Delay discounting water rate 6 sec4.87.08.82.73.02.52.6-2.32.72.6
Locomotor activity0.10.20.30.50.30.60.5-0.30.50.6
Locomotor testing distance0.30.40.90.50.60.60.9-0.20.60.8
Locomotor testing rearing1.82.83.5-1.8-1.6-1.9-1.11.8-1.8-1.7
Light reinforcement 10.00.00.10.10.00.1-0.0-0.30.10.1
Light reinforcement 21.92.52.8-1.6-1.5-1.6-1.61.5-1.7-1.7
Reaction time number correct3.95.66.32.52.22.52.2-2.52.42.2
Reaction time mean minus median0.10.20.6-0.3-0.8-0.0-0.60.1-0.2-0.2
Reaction time mean minus median AUC0.10.10.4-0.1-0.60.2-0.6-0.1-0.1-0.0
Reaction time num false alarms1.52.13.01.51.41.51.3-1.71.41.2
Reaction time num false alarms AUC1.82.53.01.61.71.61.5-1.71.61.4
Reaction time trials correct on left3.95.66.32.52.22.52.2-2.52.42.2
Reaction time trials on left4.05.66.42.52.22.52.2-2.52.42.2
Reaction time mean1.31.82.9-1.5-1.3-1.1-1.31.7-1.3-0.9
Reaction time mean AUC0.71.01.6-1.1-1.1-0.8-1.01.3-0.9-0.6
Median of all reaction times0.91.22.6-1.2-0.9-0.9-1.01.6-1.0-0.6
Reaction time omissions1.21.62.71.30.61.60.9-1.41.41.5
Reaction time false alarm rate0.10.20.30.30.50.40.4-0.40.30.3
Reaction time premature initiation rate0.60.81.50.71.20.81.2-0.40.80.9
Reaction time premature initiations2.63.74.51.92.11.92.1-1.71.91.8
Std. dev. reaction times0.70.91.5-1.1-1.1-0.7-0.91.2-0.9-0.6
Reaction time trials completed4.05.66.42.52.22.52.2-2.52.42.2
Reaction time trials AUC4.25.96.62.62.32.62.3-2.62.52.3
Social response proportion0.30.30.9-0.21.00.10.70.80.10.5
Social responses0.10.20.6-0.5-0.1-0.3-0.00.8-0.4-0.1
Social time0.91.22.50.71.41.21.00.11.01.6
Conditioned locomotion1.51.82.01.41.31.41.2-1.31.41.3
Cocaine response after cond. corrected0.40.51.1-0.5-0.7-0.7-0.80.1-0.7-1.0
Cocaine response after cond. not corrected1.51.72.6-1.1-1.4-1.3-1.40.7-1.3-1.6
Cocaine response before conditioning2.22.73.3-1.7-1.7-1.5-1.71.8-1.6-1.4
Saline control response0.10.10.30.2-0.50.2-0.5-0.40.1-0.0
Condit. Reinf. active minus inactive responses0.70.81.20.90.81.00.8-0.61.01.1
Condit. Reinf. active-inactive response ratio0.50.60.90.60.90.80.8-0.20.81.0
Condit. Reinf. active responses0.00.10.20.20.20.50.1-0.00.30.4
Condit. Reinf. inactive responses0.30.40.8-0.7-0.6-0.4-0.90.5-0.7-0.7
Condit. Reinf. lever presses1.21.62.8-1.4-1.1-1.1-1.41.7-1.2-0.9
Condit. Reinf. lever reinforcers received0.10.10.30.30.20.60.1-0.10.40.5
Pavlov. Cond. lever latency2.02.84.91.81.31.51.8-2.21.61.3
Pavlov. Cond. magazine entry latency3.94.45.7-2.1-2.1-2.0-2.42.0-2.1-2.0
Pavlov. Cond. change in total contacts4.76.59.6-2.7-2.2-2.6-2.33.1-2.6-2.3
Pavlov. Cond. index score4.05.36.7-2.3-2.1-2.2-2.52.6-2.2-2.0
Pavlov. Cond. latency score4.05.06.1-2.3-2.1-2.2-2.52.4-2.2-2.0
Pavlov. Cond. lever contacts2.63.75.4-2.0-1.6-1.8-2.12.3-1.9-1.6
Pavlov. Cond. magazine entry number2.93.64.61.91.81.82.1-2.01.91.8
Pavlov. Cond. intertrial magazine entries5.46.97.42.62.72.72.7-2.52.62.6
Pavlov. Cond. lever-magazine prob. diff.4.76.07.7-2.5-2.2-2.4-2.62.8-2.4-2.2
Pavlov. Cond. response bias2.94.15.5-2.1-1.8-1.8-2.42.3-1.9-1.7
Conditioned reinforcement - actives1.91.93.21.21.81.31.5-1.01.31.4
Conditioned reinforcement - inactives0.50.60.80.70.90.90.6-0.80.70.7
Conditioned locomotion0.20.30.9-0.3-0.4-0.4-0.90.0-0.4-0.5
Intermittent access intake day 1-15 change1.61.61.8-1.3-1.2-1.2-1.21.2-1.3-1.3
Intermittent access intake escalation1.61.61.8-1.3-1.1-1.2-1.31.2-1.3-1.3
Intermittent access intake escalation 20.30.30.4-0.5-0.4-0.6-0.40.5-0.6-0.7
Intermitt. access day 1 inactive lever presses3.23.54.11.91.72.01.8-1.81.91.9
Intermitt. access day 15 inactive lever presses1.01.11.40.91.11.21.0-0.81.01.1
Intermitt. access escalation Index0.20.20.30.30.50.30.6-0.20.40.5
Intermittent access day 1 total infusions0.10.10.4-0.0-0.2-0.2-0.7-0.3-0.2-0.4
Intermittent access day 15 total infusions1.31.52.0-1.2-1.1-1.2-1.40.9-1.3-1.4
Intermittent access terminal intake (last 3 days)1.61.82.3-1.4-1.2-1.2-1.51.0-1.4-1.5
Intermittent access total infusions0.30.30.7-0.5-0.4-0.5-0.80.1-0.6-0.7
Intermittent access day 1 locomotion0.30.31.0-0.3-0.5-0.5-1.00.0-0.4-0.6
Intermittent access day 15 total locomotion0.10.10.4-0.2-0.0-0.3-0.70.2-0.2-0.3
Intermittent access total locomotion0.10.10.5-0.1-0.3-0.2-0.7-0.3-0.2-0.4
Intermittent access standard deviation2.32.53.9-1.3-1.6-1.6-2.00.7-1.6-1.9
Cocaine induced anxiety1.51.73.51.01.71.01.9-0.51.21.3
Post-drug Anxiety1.21.32.80.91.60.81.7-0.50.91.0
Baseline Anxiety1.31.41.7-1.1-1.3-1.1-1.30.7-1.2-1.3
Lifetime Intake0.10.10.3-0.4-0.0-0.3-0.60.2-0.4-0.4
Incentive Sensitization - Responses0.00.00.1-0.20.2-0.1-0.10.3-0.10.0
Incentive Sensitization - Breakpoint0.00.00.1-0.10.30.00.00.30.00.1
Progressive ratio test 1 active lever presses0.00.00.0-0.20.10.1-0.1-0.0-0.1-0.0
Progressive ratio test 1 breakpoint0.00.00.1-0.3-0.1-0.0-0.3-0.0-0.3-0.2
Progressive ratio test 1 inactive lever presses3.13.34.01.71.72.01.8-1.81.81.9
Progressive ratio test 2 active lever presses0.00.00.1-0.10.3-0.0-0.00.1-0.1-0.0
Progressive ratio test 2 breakpoint0.00.00.20.00.40.1-0.0-0.00.10.1
Progressive ratio test 2 inactive lever presses0.60.71.40.51.20.81.1-0.20.70.9
Total sessions with >9 infusions0.00.00.1-0.10.30.0-0.10.0-0.1-0.1
Short access day 1 total inactive lever presses0.00.00.10.00.30.2-0.20.30.10.3
Short access day 10 total inactive lever presses0.60.61.00.70.71.00.6-0.50.81.0
Short access day 1 total infusions0.30.31.00.21.00.40.5-0.00.40.6
Short access day 10 total infusions0.20.20.4-0.5-0.1-0.5-0.60.3-0.5-0.5
Short access total infusions0.20.30.6-0.70.2-0.5-0.40.7-0.6-0.4
Short access day 1 locomotion0.30.40.6-0.6-0.3-0.6-0.70.7-0.6-0.5
Short access day 10 total locomotion0.30.30.6-0.3-0.6-0.5-0.8-0.2-0.5-0.7
Short access total locomotion0.00.00.0-0.20.1-0.1-0.2-0.0-0.1-0.1
Compulsive drug intake0.10.10.30.5-0.30.1-0.2-0.60.30.1
One hour access (0.3 mA shock)0.30.30.70.60.70.60.3-0.90.50.3
One hour access (shock baseline)0.00.00.1-0.30.30.0-0.10.1-0.2-0.2
Number of responses in last shaping day0.50.50.6-0.8-0.5-0.7-0.80.7-0.7-0.7
Context. condit. distance diff. score3.34.14.92.21.82.11.3-2.12.22.2
Locomotion velocity, session 10.20.20.20.50.40.50.3-0.40.40.4
Locomotion distance, session 10.40.50.8-0.6-0.9-0.7-0.80.4-0.7-0.9
Locomotion velocity, session 20.10.10.3-0.30.3-0.20.10.5-0.2-0.0
Locomotion distance, session 20.30.50.6-0.8-0.6-0.7-0.70.8-0.7-0.6
Locomotion velocity, session 30.10.10.2-0.1-0.4-0.2-0.4-0.2-0.2-0.3
Locomotion distance, session 30.00.00.0-0.00.00.10.00.10.00.1
Stereotopy head waving bouts, day 30.10.10.20.20.40.10.5-0.50.20.2
Stereotopy head waving duration, day 30.20.20.40.30.60.30.6-0.50.40.4
Locomotion velocity, session 70.20.20.5-0.1-0.7-0.4-0.5-0.1-0.3-0.5
Locomotion distance, session 70.81.01.1-1.0-1.0-1.0-1.01.0-1.0-0.9
Stereotopy head waving bouts, day 71.92.23.41.61.01.61.2-1.81.51.3
Stereotopy head waving duration, day 70.91.12.41.20.61.10.8-1.51.10.8
Locomotion velocity, session 81.31.52.91.50.71.30.5-1.71.41.1
Locomotion distance, session 80.30.51.00.80.20.7-0.3-1.00.80.7
Degree of sensitization distance0.30.30.4-0.6-0.5-0.7-0.30.6-0.6-0.5
Degree of sensitization stereotypy0.60.61.20.90.20.90.5-1.10.80.6
Condit. Reinf. active minus inactive responses0.50.50.8-0.7-0.7-0.7-0.80.5-0.8-0.9
Condit. Reinf. active-inactive response ratio2.52.73.0-1.6-1.7-1.6-1.71.4-1.7-1.7
Condit. Reinf. active responses0.10.10.2-0.0-0.2-0.0-0.4-0.3-0.2-0.4
Condit. Reinf. inactive responses2.12.53.11.61.71.61.4-1.81.51.3
Incentive salience index mean0.30.40.7-0.3-0.8-0.4-0.8-0.1-0.5-0.8
Condit. Reinf. lever presses0.10.10.30.1-0.4-0.1-0.4-0.5-0.1-0.4
Time in familiar zone, hab. session 10.10.10.3-0.0-0.6-0.2-0.5-0.1-0.1-0.1
Time in novel zone, hab. session 10.50.51.0-0.8-0.4-0.5-0.51.0-0.7-0.6
Total zone transitions, hab. session 10.30.50.9-0.7-0.7-0.5-1.00.8-0.5-0.3
Total locomotion distance, hab. session 10.20.30.90.40.50.70.2-0.10.60.9
Locomotion velocity, hab. session 10.71.01.60.91.11.10.8-0.71.11.3
Time in familiar zone, hab. session 20.20.20.40.3-0.6-0.1-0.6-0.60.0-0.3
Time in novel zone, hab. session 20.30.30.9-0.7-0.1-0.4-0.31.0-0.6-0.4
Total zone transitions, hab. session 20.50.61.1-0.6-1.0-0.6-1.10.4-0.7-0.9
Total locomotion distance, hab. session 20.40.50.80.60.60.90.6-0.70.70.6
Locomotion velocity, hab. session 20.50.71.10.80.81.00.8-0.90.80.8
Novel to familiar place preference ratio0.60.70.9-0.9-0.9-0.7-0.70.8-0.9-0.8
Novelty place preference0.50.50.8-0.8-0.7-0.6-0.50.9-0.8-0.6
Time in novel zone, NPP test0.30.30.4-0.5-0.7-0.4-0.50.5-0.5-0.5
Total zone transitions, NPP test0.30.41.10.7-0.30.8-0.5-1.00.60.4
Total locomotion distance, NPP test0.30.40.80.70.20.90.0-0.80.70.7
Locomotion velocity, NPP test0.30.40.70.60.30.80.1-0.70.70.7
Pavlov. Cond. lever latency0.50.61.00.61.00.70.9-0.10.71.0
Pavlov. Cond. magazine entry latency0.40.51.5-0.4-1.2-0.6-0.80.1-0.6-0.7
Pavlov. Cond. change in total contacts0.20.20.4-0.2-0.6-0.3-0.5-0.2-0.3-0.5
Pavlov. Cond. index score0.70.92.0-0.6-1.4-0.8-1.10.2-0.8-1.1
Pavlov. Cond. latency score0.50.61.4-0.6-1.2-0.7-0.90.1-0.7-1.0
Pavlov. Cond. lever contacts0.91.11.6-0.9-1.2-1.0-1.00.5-1.1-1.3
Pavlov. Cond. magazine entry number0.60.71.70.41.30.71.2-0.10.70.9
Pavlov. Cond. intertrial magazine entries7.58.910.53.22.93.12.6-3.23.12.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.6-0.6-1.3-0.8-1.00.1-0.8-1.0
Pavlov. Cond. response bias0.70.81.8-0.5-1.3-0.7-1.3-0.0-0.7-1.1
Bone: apparent density0.00.00.10.1-0.30.1-0.3-0.30.0-0.1
Bone surface0.10.10.2-0.4-0.4-0.3-0.30.4-0.3-0.2
Bone volume0.00.10.1-0.3-0.2-0.2-0.30.3-0.2-0.1
Bone: connectivity density0.30.40.70.80.30.70.2-0.80.70.7
Bone: cortical apparent density6.68.611.52.73.32.83.4-2.42.92.9
Bone: cortical area0.40.61.20.61.10.61.1-0.70.60.5
Bone: cortical porosity0.20.30.40.60.10.6-0.1-0.50.60.7
Bone: cortical porosity0.10.20.40.3-0.40.3-0.6-0.40.30.2
Bone: cortical thickness0.50.81.30.81.00.71.1-1.10.70.4
Bone: cortical thickness0.91.01.51.01.11.20.8-1.11.00.9
Bone: cortical tissue density6.78.711.62.73.32.83.4-2.32.93.0
Bone: elastic displacement0.30.30.60.20.70.60.70.10.40.7
Bone: elastic work0.10.20.8-0.50.3-0.20.30.9-0.20.1
Bone: endosteal estimation0.40.82.3-1.1-0.5-0.7-0.71.5-0.8-0.3
Bone: endosteal perimeter0.00.10.2-0.40.2-0.3-0.10.5-0.3-0.2
Bone: final force0.10.20.50.00.70.20.50.20.30.6
Bone: final moment0.10.20.60.20.80.40.5-0.00.40.7
Bone: marrow area0.30.72.3-1.1-0.5-0.6-0.61.5-0.7-0.2
Bone: maximum diameter0.10.20.3-0.50.1-0.50.20.3-0.5-0.6
Bone: maximum force0.10.20.40.20.60.30.6-0.10.30.5
Bone: maximum moment0.10.20.40.30.60.40.5-0.30.40.5
Bone: minimum diameter0.81.52.01.11.41.21.1-1.01.21.3
Bone: periosteal estimation0.10.10.3-0.30.40.00.30.6-0.10.2
Bone: periosteal perimeter0.00.00.2-0.10.4-0.10.2-0.1-0.1-0.1
Bone: post-yield work1.92.63.21.81.21.61.3-1.61.81.7
Bone: stiffness1.42.12.51.51.61.41.4-1.41.51.5
Bone: tissue strength0.10.10.3-0.4-0.2-0.20.40.6-0.3-0.2
Bone: trabecular number0.20.30.50.70.20.70.2-0.70.70.6
Bone: trabecular spacing0.10.10.1-0.3-0.1-0.2-0.30.3-0.3-0.3
Bone: trabecular thickness0.10.10.10.20.30.20.4-0.30.20.2
Bone: trabecular tissue density0.10.10.4-0.00.4-0.10.6-0.0-0.1-0.1
Breakpoint value in progressive ratio session0.10.10.4-0.2-0.1-0.5-0.20.2-0.4-0.6
Distance traveled before self-admin0.50.61.1-0.9-0.1-0.9-0.11.0-0.9-0.8
Distance traveled after self-admin0.40.40.60.50.70.70.6-0.40.60.8
Delta time in closed arm before/after self-admin0.00.00.10.20.10.1-0.3-0.30.20.1
Delta time in open arm before/after self-admin0.60.61.30.80.60.60.7-1.10.70.5
Diff in mean of infusions in LGA sessions0.10.10.50.4-0.00.10.1-0.70.1-0.3
Extinction: sum of active levers before priming0.10.10.2-0.20.2-0.4-0.20.3-0.3-0.4
Active lever presses in extinction session 61.71.62.21.31.51.31.2-1.01.31.3
Delta distance traveled before/after self-admin0.50.50.80.80.00.90.0-0.90.80.8
Delta ambulatory time before/after self-admin1.41.52.31.30.71.50.7-1.31.41.4
Time in closed arm before self-admin5.66.310.5-2.8-2.2-2.5-1.83.2-2.6-2.2
Time in closed arm after self-admin3.03.27.0-2.1-1.5-1.6-1.22.6-1.7-1.2
Time in open arm before self-admin6.97.39.12.73.02.72.4-2.72.72.6
Time in open arm after self-admin6.36.911.93.02.42.52.0-3.52.72.2
Sum of active levers in priming session hrs 5-60.50.50.9-0.7-0.2-0.9-0.40.6-0.8-0.9
Time to tail flick, vehicle, before self-admin1.31.32.91.30.61.20.7-1.71.10.8
Time to tail flick, vehicle, after self-admin0.30.31.10.7-0.40.6-0.3-1.00.50.2
Time to tail flick, test, before self-admin0.00.00.1-0.10.30.10.30.1-0.00.1
Time to tail flick, test, after self-admin2.93.05.32.01.01.91.2-2.31.81.4
Delta time to tail flick, vehicle, before/after SA0.10.10.20.3-0.30.2-0.2-0.40.20.1
Delta time to tail flick, test, before/after SA2.82.55.01.90.71.80.8-2.21.71.3
Ambulatory time before self-admin0.91.01.7-1.1-0.4-1.3-0.11.1-1.1-1.1
Ambulatory time after self-admin0.00.00.1-0.3-0.1-0.2-0.20.3-0.2-0.1
Total heroin consumption1.11.32.81.31.21.00.9-1.71.00.6
Area under the delay curve0.30.30.7-0.8-0.2-0.5-0.30.8-0.6-0.3
Delay disc. indifference point, 0s delay0.30.41.00.60.20.60.4-1.00.60.5
Delay disc. indifference point, 16s delay0.40.41.0-0.9-0.0-0.60.11.0-0.7-0.4
Delay disc. indifference point, 2s delay1.31.43.1-1.6-0.7-1.2-0.31.8-1.3-0.8
Delay disc. indifference point, 24s delay0.50.50.8-0.9-0.5-0.7-0.30.9-0.8-0.6
Delay disc. indifference point, 4s delay0.10.10.2-0.20.50.20.40.30.10.5
Delay disc. indifference point, 8s delay0.10.10.3-0.5-0.2-0.3-0.50.3-0.4-0.2
Delay discount exponential model param0.20.20.50.70.10.40.2-0.70.50.2
Delay discount hyperbolic model param0.30.30.70.90.30.50.3-0.80.60.3
Fecal boli incidents, locomotor time 11.81.93.5-1.1-1.9-1.2-1.60.5-1.3-1.6
Change in fecal boli incidents, locomotor task2.32.23.21.51.81.60.6-1.31.61.7
Time >=10cm from walls, locomotor time 10.50.52.10.9-0.10.3-0.6-1.50.4-0.2
Bouts of movement, locomotor time 11.82.04.1-1.3-2.0-1.3-1.20.9-1.4-1.5
Total resting periods, locomotor time 11.71.93.6-1.4-1.9-1.3-1.21.0-1.4-1.4
Rest time, locomotor task time 10.10.10.2-0.4-0.1-0.30.30.4-0.3-0.2
Distance moved, locomotor task time 10.50.51.9-0.8-0.1-0.6-0.31.4-0.7-0.4
Vertical activity count, locomotor time 10.30.31.00.00.60.21.00.40.20.5
Time >=10cm from walls, locomotor time 21.01.02.41.30.40.90.9-1.51.00.7
Bouts of movement, locomotor time 21.01.02.00.61.20.91.4-0.40.91.3
Total resting periods, locomotor time 20.70.81.50.41.10.71.2-0.20.81.1
Rest time, locomotor task time 20.10.10.50.00.70.20.5-0.10.10.3
Distance moved, locomotor task time 20.30.40.8-0.6-0.7-0.6-0.30.9-0.6-0.6
Vertical activity count, locomotor time 20.10.10.50.3-0.10.20.7-0.20.30.3
Weight adjusted by age0.20.20.40.50.20.60.2-0.50.60.6
Seeking ratio, delayed vs. immediate footshock0.40.40.60.70.40.80.6-0.70.70.6
Locomotion in novel chamber5.46.77.92.42.82.72.7-2.12.62.8
Locomotion in novel chamber post-restriction0.10.10.4-0.30.0-0.1-0.60.4-0.10.0
Progressive ratio0.40.51.3-0.61.1-0.20.61.1-0.20.4
Food seeking constrained by brief footshock0.50.61.90.40.80.81.4-0.40.60.7
Seeking ratio, punishment vs. effort0.30.41.30.8-0.40.70.3-1.10.50.2
Run reversals in cocaine runway, females2.22.23.5-1.6-1.8-1.3-1.11.9-1.4-1.2
Run reversals in cocaine runway, males0.20.20.80.00.60.00.90.20.20.4
Latency to leave start box in cocaine runway0.50.50.8-0.9-0.2-0.9-0.40.9-0.7-0.6
Latency to leave start box in cocaine runway, F0.50.61.2-0.7-0.6-1.1-0.40.7-0.7-0.8
Latency to leave start box in cocaine runway, M0.30.30.6-0.7-0.1-0.5-0.20.7-0.6-0.6
Cd content in liver1.31.42.71.31.01.40.5-0.81.41.6
Co content in liver1.31.51.71.31.21.31.0-1.21.31.3
Cu content in liver2.12.63.5-1.8-1.1-1.9-1.11.8-1.7-1.6
Fe content in liver0.60.81.1-1.0-0.7-1.1-0.41.0-1.0-0.8
K content in liver0.30.30.90.70.40.50.4-0.90.50.3
Mg content in liver0.20.20.50.40.70.40.4-0.30.40.4
Mn content in liver0.30.40.70.60.60.70.1-0.40.70.8
Na content in liver0.20.20.6-0.4-0.5-0.6-0.10.1-0.5-0.8
Rb content in liver0.81.11.50.91.11.11.0-0.71.11.2
Se content in liver0.00.10.2-0.1-0.3-0.2-0.50.1-0.1-0.2
Sr content in liver0.20.20.40.30.60.50.4-0.10.40.6
Zn content in liver0.10.10.40.10.60.30.40.10.20.3