Hub : Genes

Ksr2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000028630 0.07 0.04 2.5e-06 0.07 0.06 0.06 0.07 2.4e-07 2.6e-06 1.7e-06 3.7e-07
2 IL gene expression ENSRNOG00000028630 0.12 0.07 4.6e-03 0.01 0.09 0.06 0.04 2.1e-01 4.0e-03 1.5e-02 4.3e-02
3 Liver alternative polyA ENSRNOT00000046190 0.19 0.08 0.0e+00 0.2 0.19 0.2 0.19 1.6e-21 1.0e-20 2.7e-21 5.9e-21
4 Liver alternative polyA ENSRNOT00000103994 0.2 0.08 0.0e+00 0.21 0.2 0.2 0.2 1.5e-22 1.1e-21 2.3e-22 4.6e-22
5 Liver isoform ratio ENSRNOT00000071074 0.14 0.06 6.7e-16 0.16 0.15 0.15 0.15 3.1e-17 2.0e-16 6.6e-16 1.4e-16
6 Liver isoform ratio ENSRNOT00000103994 0.15 0.07 2.8e-16 0.16 0.16 0.15 0.16 1.1e-17 4.9e-17 1.4e-16 4.1e-17
7 Liver isoform ratio ENSRNOT00000105197 0.14 0.06 1.8e-15 0.16 0.15 0.14 0.15 7.6e-17 4.7e-16 1.6e-15 2.8e-16
8 NAcc alternative TSS ENSRNOT00000071074 0.13 0.1 2.7e-05 0.06 0.04 0.05 0.06 6.3e-05 4.7e-04 2.4e-04 4.1e-05
9 NAcc alternative TSS ENSRNOT00000103994 0.1 0.08 9.5e-05 0.05 0.04 0.04 0.05 7.1e-05 6.1e-04 2.9e-04 1.4e-04
10 PL gene expression ENSRNOG00000028630 0.04 0.02 1.6e-03 0.03 0.03 0 0.03 1.9e-03 3.3e-03 3.4e-01 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.41.45.4-0.61.10.7-0.70.7-0.7-0.72.0-2.3-0.5
BMI without tail0.40.71.0-0.90.21.0-1.01.0-1.0-1.00.7-1.0-0.7
Body weight0.41.74.8-1.01.01.1-1.11.1-1.1-1.11.7-2.2-1.1
Epididymis fat weight1.43.34.51.71.8-2.12.1-2.12.12.11.2-0.71.4
Glucose1.21.83.0-1.7-0.91.6-1.61.6-1.6-1.60.3-1.0-0.6
Heart weight1.01.42.31.10.9-1.31.3-1.31.31.30.8-0.51.5
Left kidney weight1.13.38.31.81.3-1.71.7-1.71.71.72.0-1.22.9
Right kidney weight1.13.06.51.71.3-1.61.6-1.61.61.62.0-1.22.6
Tail length0.00.00.00.2-0.0-0.10.1-0.10.10.1-0.10.1-0.0
Length with tail0.00.10.4-0.00.40.2-0.20.2-0.2-0.20.4-0.6-0.5
Length without tail0.40.92.90.61.3-0.50.5-0.50.50.51.6-1.70.5
Liver weight, left1.72.84.3-1.9-0.82.1-2.12.1-2.1-2.10.1-1.0-1.0
Liver weight, right0.30.51.8-0.20.90.2-0.20.2-0.2-0.21.3-1.30.5
Parametrial fat weight0.10.31.0-0.4-0.50.2-0.20.2-0.2-0.2-0.90.6-1.0
Retroperitoneal fat weight0.20.81.50.61.2-0.90.9-0.90.90.91.0-0.80.5
Intraocular pressure0.40.51.30.70.8-0.50.5-0.50.50.51.2-0.71.1
Extensor digitorum longus weight0.41.62.41.51.4-1.21.2-1.21.21.21.4-1.10.8
Soleus weight0.41.12.61.60.7-1.21.2-1.21.21.20.5-0.30.7
Tibialis anterior weight5.619.226.05.14.3-4.74.7-4.74.74.73.4-2.24.7
Tibia length2.05.77.1-2.4-2.22.6-2.62.6-2.6-2.6-2.11.6-2.7
Number of licking bursts1.72.03.61.91.8-1.31.3-1.31.31.31.4-1.11.2
Food consumed during 24 hour testing period0.70.82.8-0.5-0.30.9-0.90.9-0.9-0.9-0.0-0.6-1.7
Times rat made contact with spout0.20.21.90.2-0.20.0-0.00.0-0.0-0.0-0.50.1-1.4
Mean time between licks in bursts0.50.71.70.70.5-0.90.9-0.90.90.90.60.11.3
Mean num. licks in bursts2.83.44.8-2.1-2.21.7-1.71.7-1.7-1.7-2.01.5-2.2
Std. dev. time between licks in bursts0.10.10.20.40.1-0.30.3-0.30.30.3-0.00.50.4
Water consumed over 24 hours0.10.10.90.5-0.0-0.10.1-0.10.10.10.0-0.3-0.9
Indifference point 0 sec0.10.10.20.1-0.1-0.40.4-0.40.40.40.1-0.10.1
Indifference point AUC0.00.00.1-0.3-0.4-0.10.1-0.10.10.1-0.00.1-0.0
Indifference point function ln k0.20.31.30.5-0.3-0.30.3-0.30.30.3-1.01.1-0.1
Indifference point function log k0.20.31.30.5-0.3-0.30.3-0.30.30.3-1.01.1-0.1
Delay discounting total patch changes 0 sec0.00.10.1-0.1-0.3-0.30.3-0.30.30.3-0.00.00.0
Delay discounting total patch changes 12 sec0.20.30.7-0.7-0.20.5-0.50.5-0.5-0.50.6-0.9-0.1
Delay discounting total patch changes 18 sec1.92.54.60.91.5-1.41.4-1.41.41.42.1-2.21.6
Delay discounting total patch changes 24 sec0.30.40.80.30.3-0.90.9-0.90.90.90.4-0.10.2
Delay discounting total patch changes 6 sec0.00.00.2-0.1-0.0-0.20.2-0.20.20.20.4-0.4-0.1
Delay discounting time to switch 0 sec2.13.36.91.92.6-1.51.5-1.51.51.52.1-2.21.5
Delay discounting water rate 0 sec0.91.53.2-0.9-1.81.1-1.11.1-1.1-1.1-1.31.1-1.2
Delay discounting water rate 12 sec1.92.83.41.81.1-1.91.9-1.91.91.91.4-1.11.8
Delay discounting water rate 18 sec0.20.30.40.60.0-0.60.6-0.60.60.60.3-0.10.6
Delay discounting water rate 24 sec0.40.52.40.40.5-0.30.3-0.30.30.31.2-1.60.6
Delay discounting water rate 6 sec0.10.10.6-0.1-0.80.3-0.30.3-0.3-0.3-0.10.0-0.0
Locomotor activity0.10.10.10.30.3-0.40.4-0.40.40.4-0.20.3-0.1
Locomotor testing distance0.10.20.4-0.3-0.30.3-0.30.3-0.3-0.3-0.60.4-0.7
Locomotor testing rearing1.42.13.31.51.8-1.41.4-1.41.41.41.5-1.41.1
Light reinforcement 10.10.10.5-0.7-0.40.2-0.20.2-0.2-0.20.0-0.3-0.4
Light reinforcement 20.40.50.9-0.9-0.50.9-0.90.9-0.9-0.90.3-0.30.1
Reaction time number correct0.60.93.2-0.9-0.90.8-0.80.8-0.8-0.8-1.00.5-1.8
Reaction time mean minus median0.10.20.60.40.6-0.20.2-0.20.20.20.7-0.80.3
Reaction time mean minus median AUC0.10.10.30.50.2-0.30.3-0.30.30.30.3-0.20.2
Reaction time num false alarms0.10.10.6-0.2-0.80.1-0.10.1-0.1-0.1-0.20.30.1
Reaction time num false alarms AUC0.00.00.4-0.2-0.7-0.00.0-0.00.00.0-0.10.00.0
Reaction time trials correct on left0.60.93.2-0.9-0.90.8-0.80.8-0.8-0.8-1.00.5-1.8
Reaction time trials on left0.60.83.0-0.8-0.80.7-0.70.7-0.7-0.7-0.90.4-1.7
Reaction time mean0.20.31.10.50.7-0.40.4-0.40.40.40.4-0.11.1
Reaction time mean AUC0.30.41.30.60.7-0.50.5-0.50.50.50.30.11.1
Median of all reaction times0.30.51.90.60.7-0.60.6-0.60.60.60.30.21.4
Reaction time omissions0.50.71.10.61.0-0.80.8-0.80.80.81.1-0.90.6
Reaction time false alarm rate0.10.10.70.2-0.3-0.30.3-0.30.30.30.2-0.00.8
Reaction time premature initiation rate1.01.34.5-0.6-1.20.4-0.40.4-0.4-0.4-1.81.6-2.1
Reaction time premature initiations1.52.17.9-1.0-1.50.8-0.80.8-0.8-0.8-2.11.6-2.8
Std. dev. reaction times0.20.20.40.50.5-0.40.4-0.40.40.40.7-0.60.6
Reaction time trials completed0.60.83.0-0.8-0.80.7-0.70.7-0.7-0.7-0.90.4-1.7
Reaction time trials AUC0.50.83.0-0.8-0.80.7-0.70.7-0.7-0.7-0.90.3-1.7
Social response proportion0.80.91.8-1.3-0.61.1-1.11.1-1.1-1.1-0.0-0.2-0.8
Social responses0.60.81.6-1.3-1.01.0-1.01.0-1.0-1.0-0.40.2-0.9
Social time0.20.31.5-0.1-0.3-0.20.2-0.20.20.2-0.91.2-0.2
Conditioned locomotion0.81.01.51.20.4-1.21.2-1.21.21.2-0.30.80.2
Cocaine response after cond. corrected0.91.01.51.01.1-0.80.8-0.80.80.81.2-1.21.2
Cocaine response after cond. not corrected0.30.30.40.50.6-0.50.5-0.50.50.50.5-0.60.6
Cocaine response before conditioning0.91.12.1-1.0-1.30.6-0.60.6-0.6-0.6-1.51.3-1.5
Saline control response0.20.30.70.70.2-0.50.5-0.50.50.50.10.30.9
Condit. Reinf. active minus inactive responses0.70.91.8-0.8-1.30.9-0.90.9-0.9-0.9-1.00.7-1.1
Condit. Reinf. active-inactive response ratio0.80.81.2-0.6-1.00.9-0.90.9-0.9-0.9-0.80.5-1.1
Condit. Reinf. active responses0.10.10.7-0.7-0.80.2-0.20.2-0.2-0.2-0.1-0.1-0.3
Condit. Reinf. inactive responses0.30.40.8-0.10.3-0.60.6-0.60.60.60.8-0.90.8
Condit. Reinf. lever presses1.11.53.9-1.3-2.00.6-0.60.6-0.6-0.6-1.71.7-1.2
Condit. Reinf. lever reinforcers received0.10.20.9-0.8-0.90.3-0.30.3-0.3-0.3-0.30.1-0.3
Pavlov. Cond. lever latency0.40.51.90.31.40.2-0.20.2-0.2-0.21.1-1.3-0.2
Pavlov. Cond. magazine entry latency0.50.51.6-0.3-1.20.2-0.20.2-0.2-0.2-1.31.2-0.7
Pavlov. Cond. change in total contacts0.70.92.7-0.9-1.60.7-0.70.7-0.7-0.7-1.31.3-0.6
Pavlov. Cond. index score0.50.72.4-0.8-1.50.4-0.40.4-0.4-0.4-1.21.3-0.4
Pavlov. Cond. latency score0.50.62.1-0.6-1.40.3-0.30.3-0.3-0.3-1.21.2-0.4
Pavlov. Cond. lever contacts0.71.03.5-0.6-1.80.2-0.20.2-0.2-0.2-1.51.90.0
Pavlov. Cond. magazine entry number0.60.81.60.81.2-0.80.8-0.80.80.81.0-0.90.9
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.8-0.50.7-0.70.7-0.7-0.7-0.60.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.62.0-0.7-1.40.3-0.30.3-0.3-0.3-1.11.1-0.3
Pavlov. Cond. response bias0.81.23.7-0.9-1.90.6-0.60.6-0.6-0.6-1.61.7-0.4
Conditioned reinforcement - actives0.40.31.00.00.9-0.10.1-0.10.10.11.0-1.00.9
Conditioned reinforcement - inactives0.20.20.5-0.4-0.10.5-0.50.5-0.5-0.50.1-0.6-0.7
Conditioned locomotion1.11.42.81.01.7-0.80.8-0.80.80.81.6-1.31.5
Intermittent access intake day 1-15 change0.00.00.0-0.00.2-0.00.0-0.00.00.00.00.00.1
Intermittent access intake escalation0.10.10.10.30.3-0.40.4-0.40.40.40.00.20.4
Intermittent access intake escalation 20.30.31.5-0.2-0.40.2-0.20.2-0.2-0.2-1.01.2-0.5
Intermitt. access day 1 inactive lever presses0.20.30.8-0.2-0.80.2-0.20.2-0.2-0.2-0.90.9-0.4
Intermitt. access day 15 inactive lever presses0.90.91.9-0.9-0.90.9-0.90.9-0.9-0.9-0.90.9-1.4
Intermitt. access escalation Index0.50.50.70.80.4-0.90.9-0.90.90.90.10.20.3
Intermittent access day 1 total infusions1.21.44.3-1.20.11.2-1.21.2-1.2-1.21.2-2.1-0.4
Intermittent access day 15 total infusions0.60.61.9-0.80.30.8-0.80.8-0.8-0.80.8-1.4-0.3
Intermittent access terminal intake (last 3 days)0.60.61.1-0.9-0.10.9-0.90.9-0.9-0.90.4-1.0-0.4
Intermittent access total infusions1.41.62.9-1.4-0.31.4-1.41.4-1.4-1.40.8-1.7-0.6
Intermittent access day 1 locomotion0.50.52.5-0.40.20.5-0.50.5-0.5-0.51.0-1.60.2
Intermittent access day 15 total locomotion0.40.41.20.50.6-0.50.5-0.50.50.50.8-0.71.1
Intermittent access total locomotion0.40.41.2-0.5-0.10.7-0.70.7-0.7-0.70.8-1.10.4
Intermittent access standard deviation0.70.81.1-1.00.01.1-1.11.1-1.1-1.10.3-0.8-0.4
Cocaine induced anxiety0.50.62.00.5-0.6-0.50.5-0.50.50.5-1.11.4-0.5
Post-drug Anxiety0.60.71.90.7-0.5-0.70.7-0.70.70.7-1.11.4-0.5
Baseline Anxiety0.00.00.1-0.2-0.10.2-0.20.2-0.2-0.2-0.20.2-0.1
Lifetime Intake1.21.34.4-1.10.21.1-1.11.1-1.1-1.11.3-2.1-0.3
Incentive Sensitization - Responses0.20.20.4-0.6-0.30.5-0.50.5-0.5-0.5-0.40.2-0.5
Incentive Sensitization - Breakpoint0.20.20.4-0.6-0.30.5-0.50.5-0.5-0.5-0.50.4-0.6
Progressive ratio test 1 active lever presses0.50.62.8-0.30.40.5-0.50.5-0.5-0.51.2-1.70.3
Progressive ratio test 1 breakpoint0.60.63.2-0.10.50.3-0.30.3-0.3-0.31.4-1.80.5
Progressive ratio test 1 inactive lever presses2.83.04.3-1.9-0.82.1-2.12.1-2.1-2.1-0.1-1.1-1.6
Progressive ratio test 2 active lever presses0.30.31.0-0.40.40.4-0.40.4-0.4-0.40.7-1.00.3
Progressive ratio test 2 breakpoint0.40.40.9-0.70.10.7-0.70.7-0.7-0.70.5-0.9-0.0
Progressive ratio test 2 inactive lever presses1.72.02.7-1.6-0.81.6-1.61.6-1.6-1.6-0.6-0.2-1.7
Total sessions with >9 infusions1.11.24.6-0.90.31.0-1.01.0-1.0-1.01.4-2.10.0
Short access day 1 total inactive lever presses1.41.62.3-1.4-0.21.5-1.51.5-1.5-1.50.1-1.1-1.2
Short access day 10 total inactive lever presses3.33.75.8-1.8-1.71.8-1.81.8-1.8-1.8-2.21.8-2.4
Short access day 1 total infusions1.41.53.6-1.20.21.3-1.31.3-1.3-1.31.0-1.9-0.6
Short access day 10 total infusions0.80.94.2-0.50.70.5-0.50.5-0.5-0.51.5-2.10.3
Short access total infusions1.41.66.6-1.00.41.0-1.01.0-1.0-1.01.7-2.60.0
Short access day 1 locomotion1.71.84.90.81.3-0.60.6-0.60.60.62.2-2.22.0
Short access day 10 total locomotion0.70.81.2-1.0-0.61.1-1.11.1-1.1-1.10.2-0.5-0.0
Short access total locomotion1.11.15.0-0.60.20.8-0.80.8-0.8-0.81.5-2.20.6
Compulsive drug intake0.60.62.50.3-0.6-0.40.4-0.40.40.4-1.31.6-0.4
One hour access (0.3 mA shock)0.20.30.4-0.7-0.40.5-0.50.5-0.5-0.5-0.60.5-0.5
One hour access (shock baseline)0.40.40.9-0.70.20.7-0.70.7-0.7-0.70.6-0.9-0.1
Number of responses in last shaping day0.70.71.1-0.9-0.41.0-1.01.0-1.0-1.0-0.50.6-0.4
Context. condit. distance diff. score0.60.73.70.2-0.8-0.20.2-0.20.20.2-1.51.9-0.7
Locomotion velocity, session 10.10.10.6-0.10.3-0.30.3-0.30.30.3-0.50.2-0.7
Locomotion distance, session 10.10.10.3-0.5-0.10.5-0.50.5-0.5-0.5-0.10.1-0.0
Locomotion velocity, session 20.30.42.30.1-0.6-0.00.0-0.00.00.0-1.11.50.1
Locomotion distance, session 20.40.62.0-0.30.60.6-0.60.6-0.6-0.61.2-1.40.7
Locomotion velocity, session 30.20.20.40.70.4-0.40.4-0.40.40.4-0.30.5-0.6
Locomotion distance, session 30.00.00.20.10.4-0.10.1-0.10.10.10.1-0.1-0.5
Stereotopy head waving bouts, day 31.41.62.41.51.1-1.31.3-1.31.31.31.2-1.01.6
Stereotopy head waving duration, day 30.81.01.81.30.8-1.11.1-1.11.11.10.6-0.50.8
Locomotion velocity, session 73.13.47.7-1.9-1.31.9-1.91.9-1.9-1.9-1.40.8-2.8
Locomotion distance, session 72.83.65.0-2.2-1.42.2-2.22.2-2.2-2.2-0.90.6-1.8
Stereotopy head waving bouts, day 71.31.42.31.30.7-1.51.5-1.51.51.50.3-0.30.8
Stereotopy head waving duration, day 72.12.64.01.81.2-2.02.0-2.02.02.00.3-0.30.8
Locomotion velocity, session 80.10.10.20.30.40.1-0.10.1-0.1-0.10.5-0.40.2
Locomotion distance, session 80.10.20.3-0.3-0.40.4-0.40.4-0.4-0.4-0.40.6-0.0
Degree of sensitization distance1.61.72.6-1.6-1.21.5-1.51.5-1.5-1.5-0.60.4-0.8
Degree of sensitization stereotypy1.11.22.11.20.7-1.41.4-1.41.41.40.1-0.20.5
Condit. Reinf. active minus inactive responses3.84.35.6-2.3-1.52.4-2.42.4-2.4-2.4-1.51.4-1.7
Condit. Reinf. active-inactive response ratio0.90.91.2-1.0-0.61.1-1.11.1-1.1-1.1-0.91.0-0.5
Condit. Reinf. active responses5.06.17.3-2.6-2.12.7-2.72.7-2.7-2.7-2.12.0-2.2
Condit. Reinf. inactive responses1.51.82.4-1.5-1.31.5-1.51.5-1.5-1.5-0.90.9-1.1
Incentive salience index mean2.93.54.5-2.1-1.62.1-2.12.1-2.1-2.1-1.51.5-1.2
Condit. Reinf. lever presses0.30.40.8-0.6-0.80.6-0.60.6-0.6-0.6-0.60.90.1
Time in familiar zone, hab. session 10.50.50.7-0.5-0.50.9-0.90.9-0.9-0.90.5-0.60.6
Time in novel zone, hab. session 10.20.20.50.10.7-0.40.4-0.40.40.40.4-0.4-0.6
Total zone transitions, hab. session 10.71.04.2-0.40.70.4-0.40.4-0.4-0.41.9-2.00.9
Total locomotion distance, hab. session 10.71.01.6-1.0-0.61.3-1.31.3-1.3-1.30.4-0.60.4
Locomotion velocity, hab. session 10.60.91.4-0.8-0.41.2-1.21.2-1.2-1.20.5-0.70.6
Time in familiar zone, hab. session 20.10.20.40.60.1-0.30.3-0.30.30.3-0.00.40.6
Time in novel zone, hab. session 20.30.31.3-0.30.40.4-0.40.4-0.4-0.40.7-1.10.0
Total zone transitions, hab. session 20.91.24.0-0.70.60.8-0.80.8-0.8-0.81.7-2.00.6
Total locomotion distance, hab. session 21.31.72.5-1.1-0.21.6-1.61.6-1.6-1.61.0-1.60.1
Locomotion velocity, hab. session 20.91.22.9-0.80.01.2-1.21.2-1.2-1.21.2-1.70.3
Novel to familiar place preference ratio0.10.10.80.10.1-0.20.2-0.20.20.20.6-0.9-0.3
Novelty place preference0.10.10.30.00.0-0.10.1-0.10.10.10.4-0.5-0.4
Time in novel zone, NPP test0.10.10.3-0.2-0.10.1-0.10.1-0.1-0.10.4-0.6-0.5
Total zone transitions, NPP test0.60.92.9-0.60.60.8-0.80.8-0.8-0.81.5-1.70.4
Total locomotion distance, NPP test0.70.92.1-0.70.31.0-1.01.0-1.0-1.01.0-1.50.1
Locomotion velocity, NPP test0.50.61.7-0.50.30.8-0.80.8-0.8-0.80.9-1.30.0
Pavlov. Cond. lever latency1.41.83.31.41.8-1.21.2-1.21.21.21.6-1.60.9
Pavlov. Cond. magazine entry latency0.81.12.3-1.1-1.51.0-1.01.0-1.0-1.0-1.01.00.1
Pavlov. Cond. change in total contacts2.32.53.8-1.9-1.91.8-1.81.8-1.8-1.8-0.90.6-0.4
Pavlov. Cond. index score1.72.13.5-1.6-1.91.5-1.51.5-1.5-1.5-1.51.3-0.7
Pavlov. Cond. latency score2.22.84.5-1.7-2.11.6-1.61.6-1.6-1.6-1.91.7-1.1
Pavlov. Cond. lever contacts1.61.93.2-1.5-1.81.4-1.41.4-1.4-1.4-1.41.3-0.9
Pavlov. Cond. magazine entry number1.92.43.91.82.0-1.71.7-1.71.71.71.2-1.00.4
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.11.20.5-0.50.5-0.5-0.50.7-1.1-0.6
Pavlov. Cond. lever-magazine prob. diff.1.21.52.7-1.4-1.61.3-1.31.3-1.3-1.3-1.11.0-0.3
Pavlov. Cond. response bias1.72.03.6-1.7-1.91.6-1.61.6-1.6-1.6-1.00.8-0.2
Bone: apparent density1.11.84.11.01.6-0.90.9-0.90.90.92.0-1.81.7
Bone surface0.51.01.2-0.6-1.01.1-1.11.1-1.1-1.1-0.80.9-0.8
Bone volume0.10.10.2-0.1-0.20.4-0.40.4-0.4-0.40.1-0.0-0.0
Bone: connectivity density0.40.61.30.61.0-0.50.5-0.50.50.51.1-0.81.0
Bone: cortical apparent density0.10.10.40.30.10.3-0.30.3-0.3-0.30.3-0.60.2
Bone: cortical area4.97.48.3-2.9-2.82.9-2.92.9-2.9-2.9-2.21.9-2.8
Bone: cortical porosity2.42.63.8-1.9-2.01.8-1.81.8-1.8-1.8-0.90.9-1.2
Bone: cortical porosity3.33.65.6-2.2-2.41.9-1.91.9-1.9-1.9-1.51.5-1.6
Bone: cortical thickness1.93.24.7-1.8-1.71.9-1.91.9-1.9-1.9-1.30.9-2.2
Bone: cortical thickness1.41.72.5-1.6-1.51.3-1.31.3-1.3-1.3-0.90.5-1.6
Bone: cortical tissue density0.10.10.40.30.10.3-0.30.3-0.3-0.30.3-0.60.2
Bone: elastic displacement0.50.60.8-0.6-0.90.8-0.80.8-0.8-0.8-0.90.7-0.6
Bone: elastic work2.33.03.7-1.6-1.91.8-1.81.8-1.8-1.8-1.61.5-1.5
Bone: endosteal estimation0.30.72.1-0.6-1.30.5-0.50.5-0.5-0.5-1.21.4-0.2
Bone: endosteal perimeter1.53.15.2-1.6-2.31.7-1.71.7-1.7-1.7-2.01.9-1.3
Bone: final force2.33.74.6-2.2-2.12.1-2.12.1-2.1-2.1-1.10.7-1.9
Bone: final moment2.44.05.2-2.3-2.12.2-2.22.2-2.2-2.2-1.10.7-2.0
Bone: marrow area0.40.82.4-0.6-1.40.5-0.50.5-0.5-0.5-1.31.5-0.2
Bone: maximum diameter4.88.810.9-2.9-3.33.1-3.13.1-3.1-3.1-2.62.3-3.0
Bone: maximum force1.42.43.0-1.6-1.71.7-1.71.7-1.7-1.7-0.90.8-1.5
Bone: maximum moment1.52.63.2-1.8-1.71.8-1.81.8-1.8-1.8-0.90.8-1.6
Bone: minimum diameter1.73.14.5-1.6-2.11.8-1.81.8-1.8-1.8-1.61.6-1.2
Bone: periosteal estimation2.55.17.6-2.2-2.82.2-2.22.2-2.2-2.2-2.22.1-1.9
Bone: periosteal perimeter2.64.35.7-2.2-2.42.1-2.12.1-2.1-2.1-2.01.7-1.9
Bone: post-yield work0.30.40.6-0.7-0.40.8-0.80.8-0.8-0.80.4-0.50.1
Bone: stiffness0.20.30.4-0.6-0.10.6-0.60.6-0.6-0.60.4-0.5-0.5
Bone: tissue strength0.30.31.00.10.30.3-0.30.3-0.3-0.31.0-0.70.7
Bone: trabecular number0.81.22.90.71.2-0.90.9-0.90.90.91.5-1.21.7
Bone: trabecular spacing0.10.10.8-0.50.00.2-0.20.2-0.2-0.2-0.1-0.4-0.9
Bone: trabecular thickness0.30.31.50.50.3-0.20.2-0.20.20.20.9-0.61.2
Bone: trabecular tissue density0.10.10.20.30.3-0.40.4-0.40.40.40.3-0.20.1
Breakpoint value in progressive ratio session0.40.40.7-0.60.00.8-0.80.8-0.8-0.80.3-0.6-0.6
Distance traveled before self-admin0.50.51.11.00.7-0.70.7-0.70.70.70.6-0.80.5
Distance traveled after self-admin0.20.31.20.10.10.1-0.10.1-0.1-0.10.6-1.10.9
Delta time in closed arm before/after self-admin0.40.41.7-0.1-0.80.5-0.50.5-0.5-0.5-0.91.3-0.2
Delta time in open arm before/after self-admin0.40.40.60.80.5-0.70.7-0.70.70.70.2-0.30.8
Diff in mean of infusions in LGA sessions0.20.20.90.20.8-0.20.2-0.20.20.20.7-1.00.4
Extinction: sum of active levers before priming0.10.10.9-0.2-0.20.0-0.00.0-0.0-0.00.2-0.20.9
Active lever presses in extinction session 60.20.20.80.20.9-0.10.1-0.10.10.10.3-0.8-0.3
Delta distance traveled before/after self-admin0.20.32.00.0-0.0-0.20.2-0.20.20.20.5-0.41.4
Delta ambulatory time before/after self-admin0.10.10.6-0.4-0.40.2-0.20.2-0.2-0.20.3-0.50.8
Time in closed arm before self-admin0.30.40.60.50.6-0.80.8-0.80.80.80.10.30.1
Time in closed arm after self-admin0.50.51.50.70.0-0.70.7-0.70.70.7-0.51.20.3
Time in open arm before self-admin1.61.73.2-1.3-0.41.5-1.51.5-1.5-1.50.8-1.8-0.5
Time in open arm after self-admin0.20.21.30.20.4-0.20.2-0.20.20.20.6-1.10.5
Sum of active levers in priming session hrs 5-64.14.04.8-2.1-1.82.2-2.22.2-2.2-2.2-1.60.8-2.2
Time to tail flick, vehicle, before self-admin2.93.03.41.81.9-1.81.8-1.81.81.81.5-0.61.8
Time to tail flick, vehicle, after self-admin1.31.32.71.20.4-1.31.3-1.31.31.3-0.81.60.8
Time to tail flick, test, before self-admin0.20.20.8-0.30.50.2-0.20.2-0.2-0.20.6-0.9-0.8
Time to tail flick, test, after self-admin0.20.21.3-0.40.10.3-0.30.3-0.3-0.30.1-0.6-1.1
Delta time to tail flick, vehicle, before/after SA1.71.64.7-0.8-1.30.8-0.80.8-0.8-0.8-2.21.9-1.7
Delta time to tail flick, test, before/after SA0.30.20.9-0.0-0.60.0-0.00.0-0.0-0.0-1.00.8-0.6
Ambulatory time before self-admin0.40.41.01.00.6-0.60.6-0.60.60.60.4-0.40.9
Ambulatory time after self-admin0.10.11.00.3-0.2-0.10.1-0.10.10.10.1-0.31.0
Total heroin consumption0.70.82.50.80.0-0.90.9-0.90.90.9-0.91.60.6
Area under the delay curve0.60.61.6-0.6-1.30.5-0.50.5-0.5-0.5-1.11.0-0.8
Delay disc. indifference point, 0s delay0.10.10.30.60.2-0.40.4-0.40.40.4-0.10.1-0.3
Delay disc. indifference point, 16s delay0.40.41.40.5-0.6-0.60.6-0.60.60.6-0.81.2-0.1
Delay disc. indifference point, 2s delay0.91.02.6-1.0-0.71.0-1.01.0-1.0-1.0-0.90.4-1.6
Delay disc. indifference point, 24s delay0.20.21.50.4-0.2-0.30.3-0.30.30.30.30.11.2
Delay disc. indifference point, 4s delay1.01.01.5-1.2-0.91.2-1.21.2-1.2-1.2-0.40.2-0.6
Delay disc. indifference point, 8s delay0.70.72.7-0.7-1.60.5-0.50.5-0.5-0.5-1.11.0-0.9
Delay discount exponential model param0.60.71.70.61.3-0.60.6-0.60.60.61.1-1.10.8
Delay discount hyperbolic model param0.60.71.50.71.2-0.60.6-0.60.60.61.1-1.10.8
Fecal boli incidents, locomotor time 11.92.14.8-1.1-1.31.2-1.21.2-1.2-1.2-2.02.2-1.6
Change in fecal boli incidents, locomotor task1.31.24.5-0.00.70.4-0.40.4-0.4-0.42.0-2.11.4
Time >=10cm from walls, locomotor time 10.30.30.50.60.4-0.50.5-0.50.50.50.7-0.50.5
Bouts of movement, locomotor time 12.12.33.0-1.7-1.61.6-1.61.6-1.6-1.6-1.21.1-1.4
Total resting periods, locomotor time 11.61.82.6-1.6-1.11.6-1.61.6-1.6-1.6-0.60.6-1.0
Rest time, locomotor task time 11.41.54.70.52.2-0.30.3-0.30.30.32.0-1.71.7
Distance moved, locomotor task time 10.50.61.70.1-1.3-0.30.3-0.30.30.3-1.30.9-0.9
Vertical activity count, locomotor time 10.80.92.5-0.4-1.50.1-0.10.1-0.1-0.1-1.61.3-1.4
Time >=10cm from walls, locomotor time 20.00.00.1-0.2-0.20.2-0.20.2-0.2-0.20.3-0.10.2
Bouts of movement, locomotor time 20.10.10.50.2-0.70.1-0.10.1-0.1-0.1-0.50.5-0.0
Total resting periods, locomotor time 20.00.00.20.4-0.4-0.10.1-0.10.10.1-0.20.30.2
Rest time, locomotor task time 20.80.92.80.11.10.2-0.20.2-0.2-0.21.7-1.71.4
Distance moved, locomotor task time 20.60.72.2-0.4-1.50.3-0.30.3-0.3-0.3-1.41.0-1.2
Vertical activity count, locomotor time 20.30.41.20.0-0.7-0.10.1-0.10.10.1-1.11.0-0.9
Weight adjusted by age1.11.22.01.41.2-1.21.2-1.21.21.20.20.40.9
Seeking ratio, delayed vs. immediate footshock0.40.52.3-0.40.60.2-0.20.2-0.2-0.21.3-1.50.3
Locomotion in novel chamber0.60.81.1-1.0-0.61.0-1.01.0-1.0-1.00.4-0.7-0.6
Locomotion in novel chamber post-restriction1.72.12.8-1.5-1.11.7-1.71.7-1.7-1.70.5-1.6-0.5
Progressive ratio0.00.10.3-0.10.30.0-0.00.0-0.0-0.00.5-0.40.2
Food seeking constrained by brief footshock0.40.51.6-0.11.1-0.10.1-0.10.10.11.3-1.20.5
Seeking ratio, punishment vs. effort0.10.20.20.40.5-0.50.5-0.50.50.50.1-0.20.2
Run reversals in cocaine runway, females0.10.10.60.10.2-0.40.4-0.40.40.40.10.20.8
Run reversals in cocaine runway, males1.41.31.91.41.0-1.41.4-1.41.41.40.3-0.00.7
Latency to leave start box in cocaine runway1.31.45.10.51.0-0.30.3-0.30.30.32.0-2.31.8
Latency to leave start box in cocaine runway, F0.30.31.10.30.5-0.20.2-0.20.20.20.9-1.00.9
Latency to leave start box in cocaine runway, M1.61.55.20.51.0-0.40.4-0.40.40.42.1-2.31.9
Cd content in liver2.32.54.42.10.9-1.71.7-1.71.71.70.60.12.1
Co content in liver0.10.10.30.1-0.5-0.30.3-0.30.30.3-0.20.30.3
Cu content in liver0.40.50.80.70.4-0.90.9-0.90.90.90.00.30.1
Fe content in liver2.83.34.92.22.1-1.91.9-1.91.91.91.5-1.41.3
K content in liver0.20.20.30.40.2-0.50.5-0.50.50.50.00.30.3
Mg content in liver0.50.51.00.61.0-0.80.8-0.80.80.80.7-0.40.4
Mn content in liver0.30.31.10.1-0.4-0.50.5-0.50.50.5-0.61.00.4
Na content in liver0.10.10.80.20.0-0.00.0-0.00.00.0-0.40.1-0.9
Rb content in liver0.10.10.6-0.2-0.00.4-0.40.4-0.4-0.4-0.40.7-0.1
Se content in liver0.30.40.80.40.5-0.60.6-0.60.60.60.6-0.9-0.2
Sr content in liver0.90.81.51.0-0.2-1.01.0-1.01.01.0-0.20.91.2
Zn content in liver1.01.12.00.81.3-0.90.9-0.90.90.91.4-1.30.5