Hub : Genes

Pld4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000028566 0.11 0.09 3.3e-06 0.05 0.04 0.04 0.05 5.7e-06 5.0e-05 2.2e-05 4.1e-06
2 Brain intron excision ratio chr6:131818984:131820582 0.04 0.03 3.4e-04 0.03 0.02 0.03 0 1.0e-03 1.0e-02 1.1e-03 2.2e-01
3 Brain mRNA stability ENSRNOG00000028566 0.16 0.1 8.7e-07 0.07 0 0.06 0.01 8.5e-07 3.0e-01 2.5e-06 2.0e-02
4 Liver gene expression ENSRNOG00000028566 0.14 0.1 3.3e-12 0.11 0.09 0.1 0.11 2.6e-12 4.2e-10 1.7e-11 4.0e-12
5 Liver isoform ratio ENSRNOT00000029017 0.04 0.04 2.9e-05 0.03 0.03 0.03 0.03 1.2e-04 2.8e-04 2.1e-04 2.3e-04
6 NAcc intron excision ratio chr6:131818984:131820582 0.11 0.08 2.5e-04 0.05 0.06 0.04 0.05 8.5e-05 5.7e-05 8.4e-04 1.1e-04
7 NAcc intron excision ratio chr6:131820668:131821312 0.09 0.07 2.1e-03 0.03 0.04 0.02 0.03 1.6e-03 6.2e-04 9.0e-03 1.6e-03
8 PL intron excision ratio chr6:131818984:131820582 0.03 0.02 7.7e-03 0.01 0.02 0 0.01 6.9e-02 1.5e-02 2.1e-01 6.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.65.37.0-2.3-2.3-2.4-2.62.2-2.02.0-2.6
BMI without tail0.91.92.4-1.5-1.6-1.5-1.41.2-1.41.4-1.3
Body weight1.56.47.52.52.52.52.3-2.72.7-2.72.2
Epididymis fat weight1.84.36.7-2.1-2.1-2.2-2.21.9-1.71.7-2.6
Glucose0.00.00.10.00.0-0.00.20.1-0.20.20.3
Heart weight0.20.20.4-0.6-0.5-0.4-0.50.4-0.50.5-0.2
Left kidney weight2.88.29.12.82.93.02.5-3.02.9-2.92.8
Right kidney weight1.33.84.52.02.02.11.5-2.01.9-1.92.1
Tail length5.015.116.93.83.83.94.0-4.13.7-3.74.0
Length with tail9.535.036.65.95.96.05.9-6.15.9-5.95.8
Length without tail6.313.714.83.73.83.83.6-3.63.8-3.83.4
Liver weight, left2.54.04.12.02.02.01.9-2.02.0-2.02.0
Liver weight, right0.71.21.81.11.01.21.1-1.01.3-1.30.6
Parametrial fat weight0.10.20.2-0.4-0.4-0.4-0.50.5-0.50.5-0.4
Retroperitoneal fat weight0.00.10.4-0.3-0.3-0.4-0.10.2-0.10.1-0.6
Intraocular pressure0.30.40.7-0.7-0.7-0.7-0.40.5-0.80.8-0.4
Extensor digitorum longus weight9.939.841.66.46.46.46.3-6.46.2-6.26.2
Soleus weight2.88.110.62.82.82.92.7-2.93.3-3.31.8
Tibialis anterior weight1.24.04.72.12.12.22.0-1.92.1-2.11.6
Tibia length0.10.10.20.40.40.40.3-0.40.4-0.40.5
Number of licking bursts1.11.21.9-1.1-1.1-1.2-1.00.9-1.41.4-0.8
Food consumed during 24 hour testing period1.11.31.61.11.11.11.1-1.21.1-1.11.0
Times rat made contact with spout0.30.40.50.60.60.60.6-0.70.7-0.70.4
Mean time between licks in bursts0.71.01.2-1.0-1.0-1.0-0.91.1-1.01.0-0.9
Mean num. licks in bursts1.62.02.81.31.31.51.3-1.31.7-1.70.9
Std. dev. time between licks in bursts0.10.10.20.40.40.40.4-0.30.4-0.40.3
Water consumed over 24 hours1.21.42.41.21.21.11.1-1.30.9-0.81.6
Indifference point 0 sec6.911.112.13.33.33.43.2-3.43.5-3.53.1
Indifference point AUC8.09.411.53.13.13.03.0-3.13.4-3.42.3
Indifference point function ln k0.20.31.10.50.50.50.6-0.60.1-0.11.0
Indifference point function log k0.20.31.10.50.50.50.6-0.60.1-0.11.0
Delay discounting total patch changes 0 sec8.413.514.83.73.73.73.5-3.73.8-3.83.4
Delay discounting total patch changes 12 sec4.05.35.92.32.32.32.4-2.32.3-2.22.4
Delay discounting total patch changes 18 sec3.14.14.92.01.92.12.1-2.12.2-2.21.7
Delay discounting total patch changes 24 sec1.62.02.71.41.41.41.3-1.61.7-1.61.1
Delay discounting total patch changes 6 sec7.611.614.83.33.33.43.3-3.53.8-3.82.6
Delay discounting time to switch 0 sec12.619.220.7-4.4-4.5-4.4-4.14.5-4.34.3-4.4
Delay discounting water rate 0 sec17.728.130.85.45.45.45.0-5.45.1-5.15.5
Delay discounting water rate 12 sec4.66.912.52.62.62.62.6-2.82.0-2.03.5
Delay discounting water rate 18 sec3.34.46.52.22.32.11.8-2.31.8-1.82.6
Delay discounting water rate 24 sec2.53.45.31.91.91.91.4-2.11.5-1.52.3
Delay discounting water rate 6 sec4.05.97.12.52.62.52.2-2.42.2-2.22.7
Locomotor activity0.10.10.20.40.40.30.4-0.30.2-0.20.5
Locomotor testing distance0.10.10.30.30.30.20.4-0.20.0-0.10.5
Locomotor testing rearing1.72.63.3-1.5-1.5-1.7-1.51.8-1.61.5-1.8
Light reinforcement 10.00.00.00.00.00.1-0.0-0.10.0-0.00.1
Light reinforcement 21.31.82.5-1.3-1.2-1.5-1.31.3-1.21.2-1.6
Reaction time number correct4.46.36.92.52.52.52.6-2.52.5-2.52.5
Reaction time mean minus median0.10.10.1-0.3-0.4-0.2-0.00.4-0.30.3-0.2
Reaction time mean minus median AUC0.00.10.1-0.3-0.3-0.10.20.3-0.20.3-0.1
Reaction time num false alarms1.82.52.71.51.51.61.6-1.61.6-1.61.5
Reaction time num false alarms AUC1.82.62.81.61.61.51.6-1.71.6-1.61.6
Reaction time trials correct on left4.46.36.92.52.52.52.6-2.52.5-2.52.5
Reaction time trials on left4.56.36.92.52.52.52.6-2.52.5-2.42.5
Reaction time mean2.63.64.4-1.9-1.9-1.9-1.72.1-2.12.1-1.4
Reaction time mean AUC1.72.22.9-1.5-1.5-1.5-1.21.7-1.71.7-1.1
Median of all reaction times2.43.34.4-1.8-1.8-1.8-1.62.0-2.12.1-1.2
Reaction time omissions0.70.91.70.90.81.01.1-1.00.7-0.71.3
Reaction time false alarm rate0.10.10.10.30.30.20.2-0.40.3-0.30.3
Reaction time premature initiation rate0.20.20.40.40.40.50.7-0.30.2-0.30.7
Reaction time premature initiations2.23.14.01.81.71.82.0-1.71.6-1.61.9
Std. dev. reaction times1.72.33.0-1.5-1.6-1.5-1.11.7-1.71.7-1.1
Reaction time trials completed4.56.36.92.52.52.52.6-2.52.5-2.42.5
Reaction time trials AUC4.66.66.92.62.62.62.6-2.62.5-2.52.6
Social response proportion0.90.91.6-0.9-0.8-1.0-1.10.9-1.31.3-0.2
Social responses0.60.81.1-0.8-0.9-0.9-0.80.9-1.01.1-0.5
Social time0.30.30.8-0.4-0.4-0.4-0.20.3-0.90.90.7
Conditioned locomotion1.72.02.11.41.41.41.5-1.41.4-1.41.4
Cocaine response after cond. corrected0.10.10.30.20.20.20.1-0.10.5-0.5-0.5
Cocaine response after cond. not corrected0.20.31.2-0.4-0.4-0.4-0.50.5-0.00.0-1.1
Cocaine response before conditioning2.83.43.9-1.9-1.9-2.0-1.81.8-1.81.8-1.7
Saline control response0.10.10.20.30.30.50.4-0.10.4-0.40.2
Condit. Reinf. active minus inactive responses0.30.40.90.70.70.60.6-0.70.4-0.40.9
Condit. Reinf. active-inactive response ratio0.10.10.40.40.40.20.1-0.3-0.00.00.6
Condit. Reinf. active responses0.00.00.0-0.0-0.0-0.1-0.0-0.1-0.20.20.2
Condit. Reinf. inactive responses0.30.30.5-0.7-0.7-0.6-0.40.5-0.50.5-0.6
Condit. Reinf. lever presses2.23.03.5-1.7-1.8-1.7-1.71.8-1.91.9-1.4
Condit. Reinf. lever reinforcers received0.00.00.10.0-0.0-0.10.1-0.1-0.20.20.3
Pavlov. Cond. lever latency3.54.85.42.22.22.22.1-2.32.3-2.31.8
Pavlov. Cond. magazine entry latency3.54.04.8-2.0-2.0-1.9-2.02.2-1.91.9-2.1
Pavlov. Cond. change in total contacts6.28.69.5-2.9-2.9-2.9-3.03.1-3.03.0-2.7
Pavlov. Cond. index score4.86.27.0-2.5-2.5-2.4-2.52.7-2.52.5-2.3
Pavlov. Cond. latency score4.15.26.0-2.3-2.3-2.2-2.32.5-2.22.2-2.3
Pavlov. Cond. lever contacts3.54.95.3-2.2-2.2-2.2-2.22.3-2.32.3-2.0
Pavlov. Cond. magazine entry number3.03.64.41.91.91.81.9-2.11.8-1.81.9
Pavlov. Cond. intertrial magazine entries4.35.66.82.42.42.22.5-2.62.1-2.12.6
Pavlov. Cond. lever-magazine prob. diff.5.47.07.9-2.7-2.7-2.6-2.62.8-2.62.6-2.5
Pavlov. Cond. response bias3.65.05.4-2.2-2.2-2.2-2.32.3-2.32.3-2.1
Conditioned reinforcement - actives0.90.91.51.01.00.91.1-0.90.7-0.71.2
Conditioned reinforcement - inactives0.40.51.00.70.60.51.0-0.70.5-0.50.7
Conditioned locomotion0.00.00.1-0.0-0.0-0.10.10.10.1-0.1-0.3
Intermittent access intake day 1-15 change1.31.31.8-1.1-1.1-1.2-1.01.2-1.11.1-1.3
Intermittent access intake escalation1.21.21.7-1.1-1.1-1.1-1.01.2-1.01.0-1.3
Intermittent access intake escalation 20.10.10.3-0.3-0.3-0.3-0.20.4-0.20.2-0.6
Intermitt. access day 1 inactive lever presses3.03.34.41.81.81.82.1-1.71.6-1.61.9
Intermitt. access day 15 inactive lever presses0.40.51.00.70.70.61.0-0.50.4-0.40.9
Intermitt. access escalation Index0.00.00.10.10.10.1-0.1-0.1-0.10.10.3
Intermittent access day 1 total infusions0.10.10.20.40.50.30.2-0.30.5-0.5-0.0
Intermittent access day 15 total infusions0.70.81.4-0.8-0.7-0.9-1.00.9-0.80.8-1.2
Intermittent access terminal intake (last 3 days)1.01.11.9-0.9-0.9-1.1-1.01.1-0.90.9-1.4
Intermittent access total infusions0.00.00.2-0.0-0.0-0.2-0.20.1-0.10.1-0.5
Intermittent access day 1 locomotion0.00.00.10.00.1-0.1-0.20.10.1-0.1-0.3
Intermittent access day 15 total locomotion0.00.00.1-0.1-0.1-0.2-0.30.2-0.20.2-0.2
Intermittent access total locomotion0.10.10.20.30.40.20.2-0.20.4-0.4-0.1
Intermittent access standard deviation0.40.41.8-0.5-0.5-0.5-0.60.6-0.10.1-1.3
Cocaine induced anxiety0.30.41.00.50.50.70.6-0.50.4-0.41.0
Post-drug Anxiety0.30.30.70.50.60.60.5-0.40.5-0.50.8
Baseline Anxiety0.60.61.2-0.8-0.8-0.8-0.90.7-0.60.6-1.1
Lifetime Intake0.10.10.2-0.2-0.2-0.3-0.40.2-0.40.4-0.4
Incentive Sensitization - Responses0.20.20.3-0.3-0.3-0.4-0.40.4-0.50.5-0.2
Incentive Sensitization - Breakpoint0.10.10.3-0.3-0.3-0.4-0.30.4-0.50.5-0.1
Progressive ratio test 1 active lever presses0.10.10.2-0.2-0.2-0.4-0.10.2-0.40.4-0.2
Progressive ratio test 1 breakpoint0.10.10.2-0.2-0.3-0.4-0.10.2-0.50.5-0.3
Progressive ratio test 1 inactive lever presses2.12.23.11.61.51.41.7-1.51.2-1.21.8
Progressive ratio test 2 active lever presses0.00.00.1-0.0-0.0-0.2-0.20.1-0.30.3-0.1
Progressive ratio test 2 breakpoint0.00.00.00.10.1-0.1-0.10.0-0.20.20.0
Progressive ratio test 2 inactive lever presses0.10.10.20.20.1-0.10.2-0.1-0.30.30.5
Total sessions with >9 infusions0.00.00.1-0.1-0.1-0.3-0.30.0-0.30.3-0.1
Short access day 1 total inactive lever presses0.10.10.1-0.2-0.2-0.3-0.1-0.2-0.40.40.0
Short access day 10 total inactive lever presses0.10.20.50.30.30.30.7-0.20.0-0.00.7
Short access day 1 total infusions0.00.00.10.00.0-0.1-0.1-0.2-0.30.30.3
Short access day 10 total infusions0.20.30.4-0.4-0.4-0.6-0.60.3-0.60.6-0.5
Short access total infusions0.80.91.3-0.8-0.8-0.9-1.10.7-1.11.1-0.7
Short access day 1 locomotion0.40.40.5-0.6-0.7-0.7-0.60.6-0.70.7-0.6
Short access day 10 total locomotion0.00.00.10.10.1-0.00.20.00.2-0.2-0.3
Short access total locomotion0.00.00.1-0.1-0.1-0.2-0.20.1-0.20.2-0.1
Compulsive drug intake0.70.71.20.80.80.80.6-0.91.1-1.10.5
One hour access (0.3 mA shock)0.70.81.10.90.90.91.0-0.90.9-0.90.6
One hour access (shock baseline)0.10.10.1-0.2-0.2-0.20.10.4-0.40.4-0.3
Number of responses in last shaping day0.70.70.8-0.8-0.8-0.9-0.90.9-0.90.9-0.8
Context. condit. distance diff. score3.54.25.02.22.22.12.0-2.01.8-1.82.2
Locomotion velocity, session 10.20.20.40.60.50.50.6-0.40.4-0.50.5
Locomotion distance, session 10.10.10.5-0.1-0.1-0.3-0.20.5-0.20.2-0.7
Locomotion velocity, session 20.30.40.6-0.6-0.6-0.6-0.50.8-0.70.7-0.3
Locomotion distance, session 20.70.91.3-0.9-0.8-0.9-1.11.0-1.11.1-0.8
Locomotion velocity, session 30.00.00.00.20.10.20.10.20.2-0.2-0.2
Locomotion distance, session 30.00.00.1-0.0-0.1-0.0-0.00.3-0.20.2-0.0
Stereotopy head waving bouts, day 30.10.10.10.20.30.30.1-0.30.3-0.30.2
Stereotopy head waving duration, day 30.10.10.10.30.30.30.2-0.30.2-0.20.3
Locomotion velocity, session 70.10.10.30.30.20.20.3-0.30.5-0.5-0.1
Locomotion distance, session 70.81.01.1-1.0-1.0-1.1-0.91.0-1.01.0-1.0
Stereotopy head waving bouts, day 72.83.23.41.71.81.81.9-1.71.8-1.81.6
Stereotopy head waving duration, day 71.92.32.71.51.51.61.6-1.51.7-1.61.2
Locomotion velocity, session 82.52.93.31.81.81.81.5-1.71.8-1.81.5
Locomotion distance, session 80.60.81.31.11.11.00.7-0.90.8-0.80.8
Degree of sensitization distance0.30.30.4-0.6-0.5-0.7-0.60.4-0.50.5-0.5
Degree of sensitization stereotypy1.11.21.51.01.01.11.2-1.11.2-1.20.9
Condit. Reinf. active minus inactive responses0.20.20.5-0.4-0.4-0.3-0.20.5-0.20.2-0.7
Condit. Reinf. active-inactive response ratio1.41.52.5-1.2-1.3-1.2-1.11.3-1.01.0-1.6
Condit. Reinf. active responses0.10.20.30.30.30.50.5-0.30.6-0.6-0.1
Condit. Reinf. inactive responses2.53.03.51.71.71.91.8-1.61.8-1.81.6
Incentive salience index mean0.10.10.30.20.20.30.3-0.20.5-0.5-0.4
Condit. Reinf. lever presses0.30.40.80.60.60.60.6-0.80.9-0.90.1
Time in familiar zone, hab. session 10.00.00.0-0.00.10.10.1-0.10.0-0.1-0.0
Time in novel zone, hab. session 11.01.01.1-0.9-0.9-1.0-1.11.0-1.01.1-0.8
Total zone transitions, hab. session 10.71.01.3-0.9-0.9-1.0-1.11.0-1.11.2-0.6
Total locomotion distance, hab. session 10.10.10.2-0.1-0.1-0.1-0.20.3-0.50.50.5
Locomotion velocity, hab. session 10.20.31.00.50.50.50.5-0.30.2-0.21.0
Time in familiar zone, hab. session 20.70.71.20.80.90.90.6-0.91.1-1.10.3
Time in novel zone, hab. session 21.21.21.6-1.1-1.2-1.1-1.01.2-1.31.3-0.7
Total zone transitions, hab. session 20.10.10.4-0.2-0.3-0.3-0.30.5-0.10.1-0.7
Total locomotion distance, hab. session 20.20.20.40.50.50.60.5-0.40.4-0.40.6
Locomotion velocity, hab. session 20.30.40.60.70.70.70.7-0.60.6-0.50.8
Novel to familiar place preference ratio0.70.70.9-0.8-0.9-0.9-0.60.9-0.90.9-0.9
Novelty place preference0.90.91.2-0.9-1.0-1.0-0.71.0-1.11.1-0.9
Time in novel zone, NPP test0.30.30.4-0.5-0.6-0.6-0.30.6-0.60.6-0.6
Total zone transitions, NPP test0.60.91.21.11.01.01.0-0.81.0-1.00.7
Total locomotion distance, NPP test0.30.50.60.80.80.70.8-0.50.6-0.60.7
Locomotion velocity, NPP test0.20.20.40.60.60.50.6-0.30.4-0.30.6
Pavlov. Cond. lever latency0.00.10.30.00.10.10.00.0-0.30.30.5
Pavlov. Cond. magazine entry latency0.00.00.20.00.0-0.2-0.2-0.30.2-0.2-0.4
Pavlov. Cond. change in total contacts0.00.00.10.10.10.10.1-0.20.4-0.4-0.2
Pavlov. Cond. index score0.10.10.4-0.0-0.1-0.2-0.1-0.10.3-0.3-0.6
Pavlov. Cond. latency score0.00.10.3-0.0-0.1-0.2-0.0-0.10.2-0.2-0.5
Pavlov. Cond. lever contacts0.20.20.9-0.4-0.5-0.6-0.50.3-0.20.2-0.9
Pavlov. Cond. magazine entry number0.10.10.2-0.2-0.20.1-0.00.3-0.40.40.4
Pavlov. Cond. intertrial magazine entries9.110.912.43.33.43.53.4-2.93.3-3.33.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.0-0.1-0.2-0.1-0.10.3-0.3-0.6
Pavlov. Cond. response bias0.10.10.30.30.20.10.1-0.40.6-0.5-0.5
Bone: apparent density0.00.10.10.20.20.30.2-0.20.3-0.30.1
Bone surface0.30.50.7-0.6-0.6-0.6-0.80.8-0.80.8-0.4
Bone volume0.20.40.5-0.6-0.6-0.5-0.70.7-0.70.7-0.3
Bone: connectivity density0.40.60.60.80.80.80.7-0.80.8-0.80.8
Bone: cortical apparent density3.85.07.32.32.32.22.4-2.21.9-1.92.7
Bone: cortical area0.20.30.40.60.70.60.5-0.30.5-0.50.5
Bone: cortical porosity0.10.10.30.30.30.40.3-0.50.2-0.20.6
Bone: cortical porosity0.20.20.40.40.40.50.3-0.60.5-0.50.4
Bone: cortical thickness0.81.31.61.21.31.21.2-1.01.3-1.30.8
Bone: cortical thickness0.60.71.00.90.91.01.0-0.60.7-0.70.9
Bone: cortical tissue density3.74.97.42.22.22.22.3-2.21.8-1.82.7
Bone: elastic displacement0.10.20.4-0.3-0.4-0.3-0.00.4-0.60.60.2
Bone: elastic work1.01.42.2-1.2-1.2-1.1-1.01.1-1.51.5-0.5
Bone: endosteal estimation1.73.65.0-1.9-1.9-1.8-1.91.8-2.22.2-1.1
Bone: endosteal perimeter0.20.40.8-0.6-0.6-0.5-0.90.7-0.70.7-0.4
Bone: final force0.20.40.7-0.5-0.4-0.5-0.70.5-0.90.90.0
Bone: final moment0.10.20.4-0.3-0.2-0.3-0.50.3-0.60.60.2
Bone: marrow area1.73.65.0-1.9-1.9-1.8-1.91.9-2.22.2-1.0
Bone: maximum diameter0.10.20.3-0.4-0.3-0.3-0.50.6-0.40.4-0.6
Bone: maximum force0.00.00.1-0.1-0.0-0.1-0.30.1-0.30.30.2
Bone: maximum moment0.00.00.10.10.10.1-0.1-0.2-0.00.10.4
Bone: minimum diameter0.40.71.30.90.90.90.6-0.90.6-0.61.1
Bone: periosteal estimation0.40.81.4-0.8-0.8-0.8-0.91.0-1.21.2-0.3
Bone: periosteal perimeter0.00.00.1-0.1-0.0-0.0-0.20.1-0.10.1-0.1
Bone: post-yield work2.02.73.31.71.81.71.5-1.51.6-1.61.8
Bone: stiffness1.01.62.11.31.41.41.1-1.31.1-1.11.5
Bone: tissue strength0.40.40.6-0.6-0.6-0.7-0.80.4-0.70.7-0.4
Bone: trabecular number0.30.40.50.70.70.70.7-0.60.7-0.60.7
Bone: trabecular spacing0.10.10.1-0.2-0.3-0.3-0.10.2-0.20.2-0.3
Bone: trabecular thickness0.00.00.10.20.20.20.2-0.10.2-0.20.2
Bone: trabecular tissue density0.00.00.00.10.10.10.00.10.1-0.1-0.1
Breakpoint value in progressive ratio session0.10.10.20.20.20.20.1-0.20.5-0.5-0.3
Distance traveled before self-admin1.01.01.2-1.0-1.0-1.1-1.01.1-1.01.0-0.9
Distance traveled after self-admin0.10.10.30.30.30.10.1-0.1-0.10.10.5
Delta time in closed arm before/after self-admin0.10.10.10.20.30.2-0.2-0.30.3-0.30.2
Delta time in open arm before/after self-admin1.31.22.11.11.01.11.5-1.01.2-1.20.8
Diff in mean of infusions in LGA sessions1.21.32.21.11.11.21.0-1.11.5-1.50.4
Extinction: sum of active levers before priming0.00.00.10.20.2-0.10.30.10.2-0.2-0.2
Active lever presses in extinction session 61.51.51.81.21.21.31.3-1.11.1-1.11.3
Delta distance traveled before/after self-admin0.40.40.60.60.60.80.6-0.70.5-0.40.8
Delta ambulatory time before/after self-admin0.91.01.71.01.01.11.1-1.00.7-0.71.3
Time in closed arm before self-admin8.49.610.7-3.2-3.2-3.2-2.83.3-3.23.2-2.8
Time in closed arm after self-admin7.98.210.2-2.9-2.9-2.8-3.02.9-3.23.2-2.0
Time in open arm before self-admin6.26.67.72.62.62.72.3-2.82.4-2.42.7
Time in open arm after self-admin11.412.614.63.63.53.63.5-3.63.8-3.83.0
Sum of active levers in priming session hrs 5-60.20.20.5-0.3-0.3-0.4-0.40.5-0.20.2-0.7
Time to tail flick, vehicle, before self-admin3.13.15.41.71.61.82.3-1.61.8-1.81.3
Time to tail flick, vehicle, after self-admin1.01.11.60.90.91.11.1-1.11.3-1.20.7
Time to tail flick, test, before self-admin0.10.10.2-0.2-0.3-0.3-0.10.4-0.50.5-0.1
Time to tail flick, test, after self-admin5.25.46.52.22.22.42.1-2.52.5-2.52.0
Delta time to tail flick, vehicle, before/after SA0.20.20.30.30.40.40.1-0.50.5-0.50.3
Delta time to tail flick, test, before/after SA5.34.85.92.12.12.12.0-2.32.4-2.41.9
Ambulatory time before self-admin1.01.11.4-1.0-1.0-1.1-1.21.1-0.90.9-1.1
Ambulatory time after self-admin0.20.20.4-0.4-0.4-0.4-0.60.5-0.50.5-0.3
Total heroin consumption2.93.54.81.82.01.81.7-1.82.2-2.21.3
Area under the delay curve1.51.62.5-1.2-1.3-1.3-0.71.3-1.61.6-0.8
Delay disc. indifference point, 0s delay0.40.40.80.60.60.60.9-0.50.6-0.60.6
Delay disc. indifference point, 16s delay1.81.82.6-1.2-1.3-1.4-1.01.4-1.61.6-0.9
Delay disc. indifference point, 2s delay4.44.96.5-2.2-2.3-2.2-1.82.3-2.52.5-1.6
Delay disc. indifference point, 24s delay1.31.31.7-1.1-1.2-1.2-0.91.2-1.31.3-0.9
Delay disc. indifference point, 4s delay0.60.71.4-0.7-0.8-0.8-0.40.8-1.21.2-0.1
Delay disc. indifference point, 8s delay0.50.50.9-0.8-0.8-0.8-0.20.7-0.90.9-0.5
Delay discount exponential model param1.21.32.11.11.21.20.6-1.11.4-1.40.7
Delay discount hyperbolic model param1.51.62.61.31.41.30.7-1.31.6-1.60.8
Fecal boli incidents, locomotor time 10.20.21.1-0.4-0.3-0.4-0.20.30.1-0.1-1.1
Change in fecal boli incidents, locomotor task1.51.42.41.21.21.21.0-1.20.9-0.91.5
Time >=10cm from walls, locomotor time 13.53.55.81.91.81.91.4-1.92.4-2.40.8
Bouts of movement, locomotor time 11.01.11.8-1.2-1.1-1.0-0.61.1-0.90.9-1.3
Total resting periods, locomotor time 11.21.31.9-1.2-1.2-1.1-0.81.2-1.11.1-1.4
Rest time, locomotor task time 10.40.40.7-0.6-0.5-0.7-0.30.6-0.80.9-0.4
Distance moved, locomotor task time 11.11.21.9-1.0-1.1-1.1-1.41.1-1.21.2-0.8
Vertical activity count, locomotor time 10.20.20.4-0.4-0.4-0.4-0.60.5-0.60.60.0
Time >=10cm from walls, locomotor time 23.13.24.31.81.71.71.9-1.82.1-2.11.2
Bouts of movement, locomotor time 20.20.20.6-0.1-0.1-0.20.30.2-0.80.80.6
Total resting periods, locomotor time 20.30.30.8-0.2-0.2-0.30.10.4-0.90.90.4
Rest time, locomotor task time 20.10.10.3-0.2-0.2-0.10.20.2-0.50.50.0
Distance moved, locomotor task time 20.40.50.9-0.6-0.7-0.7-0.90.7-0.60.5-0.6
Vertical activity count, locomotor time 20.00.00.10.20.10.2-0.1-0.10.3-0.30.3
Weight adjusted by age0.10.20.40.50.60.30.2-0.20.3-0.30.6
Seeking ratio, delayed vs. immediate footshock0.40.50.60.70.80.70.5-0.70.6-0.60.7
Locomotion in novel chamber2.63.25.81.81.81.71.9-1.81.3-1.32.4
Locomotion in novel chamber post-restriction0.30.30.4-0.7-0.7-0.5-0.60.4-0.70.7-0.2
Progressive ratio2.02.34.0-1.4-1.4-1.5-1.41.4-2.02.0-0.6
Food seeking constrained by brief footshock0.10.10.20.10.10.20.4-0.2-0.10.20.4
Seeking ratio, punishment vs. effort1.41.72.31.31.21.41.4-1.21.5-1.50.8
Run reversals in cocaine runway, females3.13.13.4-1.8-1.8-1.8-1.61.8-1.81.8-1.6
Run reversals in cocaine runway, males0.10.10.2-0.3-0.3-0.2-0.40.2-0.40.40.1
Latency to leave start box in cocaine runway0.91.01.4-0.9-1.0-1.0-0.81.2-1.11.1-0.9
Latency to leave start box in cocaine runway, F0.30.30.5-0.5-0.5-0.6-0.60.6-0.40.4-0.7
Latency to leave start box in cocaine runway, M0.70.71.1-0.8-0.8-0.8-0.41.0-0.90.9-0.8
Cd content in liver0.50.61.60.70.70.70.8-0.70.3-0.41.3
Co content in liver1.21.41.81.21.21.31.3-0.91.0-1.01.3
Cu content in liver2.42.83.4-1.7-1.7-1.7-1.81.6-1.61.6-1.8
Fe content in liver1.11.31.6-1.2-1.2-1.2-1.31.0-1.21.2-1.0
K content in liver1.21.21.51.01.11.10.9-1.21.2-1.20.7
Mg content in liver0.10.10.20.20.30.30.2-0.40.3-0.30.4
Mn content in liver0.10.10.40.30.30.20.2-0.30.1-0.10.6
Na content in liver0.00.00.2-0.0-0.00.00.0-0.20.3-0.3-0.4
Rb content in liver0.30.30.80.60.60.60.5-0.50.2-0.20.9
Se content in liver0.00.00.0-0.1-0.1-0.1-0.1-0.0-0.00.0-0.1
Sr content in liver0.10.10.3-0.0-0.0-0.0-0.10.3-0.50.50.2
Zn content in liver0.00.00.1-0.1-0.2-0.2-0.00.2-0.40.40.1