Hub : Genes

Hibch

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000028557 0.31 0.11 0.0e+00 0.21 0.22 0.22 0.22 1.6e-22 4.1e-24 9.2e-24 1.5e-23
2 Adipose isoform ratio ENSRNOT00000040650 0.02 0.02 5.7e-03 0 0 -0 0 1.8e-01 9.2e-02 8.6e-01 3.2e-01
3 Adipose intron excision ratio chr9:48590819:48603695 0.07 0.05 1.7e-07 0.03 0.03 0.02 0.04 4.2e-04 1.3e-04 1.8e-03 8.4e-05
4 Adipose mRNA stability ENSRNOG00000028557 0.18 0.08 4.0e-15 0.1 0.11 0.1 0.1 2.6e-11 5.0e-12 1.3e-11 4.2e-11
5 BLA gene expression ENSRNOG00000028557 0.09 0.06 5.4e-05 0.07 0.07 0.08 0.08 1.1e-04 8.7e-05 2.9e-05 3.9e-05
6 BLA mRNA stability ENSRNOG00000028557 0.29 0.12 1.1e-16 0.18 0.24 0.25 0.26 5.2e-10 2.6e-13 1.4e-13 3.4e-14
7 Brain gene expression ENSRNOG00000028557 0.26 0.11 0.0e+00 0.28 0.28 0.27 0.27 1.1e-25 8.9e-26 5.9e-25 2.3e-25
8 Brain mRNA stability ENSRNOG00000028557 0.65 0.14 0.0e+00 0.44 0.44 0.44 0.44 7.2e-44 4.1e-45 9.9e-45 1.8e-44
9 IL gene expression ENSRNOG00000028557 0.45 0.26 5.7e-06 0.2 0.2 0.15 0.18 2.0e-05 2.0e-05 2.4e-04 4.5e-05
10 IL mRNA stability ENSRNOG00000028557 0.38 0.15 1.1e-06 0.2 0.18 0.13 0.18 1.8e-05 3.3e-05 4.8e-04 3.9e-05
11 LHb gene expression ENSRNOG00000028557 0.48 0.2 4.0e-07 0.08 0.19 0.2 0.19 5.0e-03 3.4e-05 1.5e-05 2.3e-05
12 LHb isoform ratio ENSRNOT00000116077 0.27 0.15 1.9e-03 0.1 0.08 0.06 0.06 2.1e-03 5.8e-03 1.9e-02 1.4e-02
13 Liver isoform ratio ENSRNOT00000029677 0.04 0.03 4.9e-04 0.02 0.01 0 0.01 5.4e-03 1.7e-02 1.2e-01 3.3e-02
14 Liver isoform ratio ENSRNOT00000040650 0.04 0.04 1.5e-03 0.01 0.01 0.01 0 1.6e-02 5.6e-02 5.1e-02 1.4e-01
15 Liver mRNA stability ENSRNOG00000028557 0.05 0.03 1.6e-03 0 0.01 0.01 0 7.4e-02 1.0e-02 4.2e-02 1.1e-01
16 NAcc gene expression ENSRNOG00000028557 0.18 0.09 1.5e-13 0.15 0.16 0.14 0.15 2.7e-11 4.8e-12 2.8e-10 1.5e-11
17 NAcc isoform ratio ENSRNOT00000116077 0.06 0.04 2.1e-04 0.06 0.04 0.04 0.05 5.2e-05 2.7e-04 4.4e-04 2.4e-04
18 NAcc mRNA stability ENSRNOG00000028557 0.19 0.09 1.1e-16 0.21 0.22 0.22 0.22 2.5e-15 3.9e-16 3.7e-16 5.2e-16
19 OFC gene expression ENSRNOG00000028557 0.28 0.13 2.3e-05 0.2 0.18 0.16 0.2 1.5e-05 5.3e-05 1.3e-04 1.5e-05
20 OFC mRNA stability ENSRNOG00000028557 0.35 0.15 1.2e-06 0.15 0.15 0.16 0.21 2.1e-04 2.1e-04 1.0e-04 1.2e-05
21 PL gene expression ENSRNOG00000028557 0.2 0.1 1.1e-16 0.21 0.22 0.22 0.22 9.2e-16 2.4e-16 1.2e-16 5.7e-17
22 PL mRNA stability ENSRNOG00000028557 0.4 0.14 0.0e+00 0.36 0.37 0.38 0.38 2.5e-28 5.1e-29 1.1e-30 7.1e-31

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail4.916.022.22.04.34.61.84.3-4.04.5-4.74.6-2.93.8-3.04.7-4.7-2.14.1-3.6-4.64.5-4.14.6-4.2
BMI without tail1.12.33.91.41.51.71.31.7-1.31.8-1.81.9-0.61.2-0.71.8-1.8-1.41.3-1.1-1.81.7-1.12.0-1.3
Body weight0.10.30.6-0.60.60.7-0.70.1-0.60.3-0.50.3-0.60.6-0.60.2-0.20.70.5-0.6-0.10.4-0.70.3-0.7
Epididymis fat weight0.30.72.1-1.3-0.5-0.4-1.3-1.10.3-0.90.6-1.00.1-0.4-0.0-0.90.91.5-0.50.21.0-0.80.4-1.00.2
Glucose0.60.93.21.80.50.91.81.0-0.01.1-0.71.10.50.10.61.1-1.1-1.70.20.2-0.80.7-0.01.0-0.2
Heart weight0.30.40.8-0.7-0.7-0.9-0.6-0.70.4-0.80.7-0.80.2-0.50.1-0.90.90.6-0.50.30.7-0.70.5-0.70.5
Left kidney weight0.10.20.9-0.90.20.1-0.9-0.3-0.4-0.10.0-0.3-0.50.4-0.5-0.20.20.90.3-0.50.1-0.0-0.4-0.1-0.4
Right kidney weight0.41.22.4-1.41.10.9-1.40.2-1.40.5-0.90.3-1.51.3-1.50.5-0.51.41.2-1.6-0.70.8-1.50.6-1.4
Tail length3.410.215.2-2.1-3.2-3.4-1.9-3.83.0-3.63.7-3.72.2-2.92.2-3.93.92.3-3.22.83.8-3.63.1-3.63.1
Length with tail3.312.018.8-3.2-3.3-3.5-3.1-4.32.9-4.03.9-4.11.7-2.81.9-4.34.33.5-3.12.54.2-3.82.8-4.22.9
Length without tail0.51.15.4-2.30.1-0.2-2.3-0.8-0.5-0.70.4-0.8-1.10.5-1.1-0.80.82.30.3-0.80.8-0.4-0.7-0.9-0.5
Liver weight, left0.71.14.0-2.00.4-0.1-2.0-0.3-1.1-0.3-0.2-0.3-1.60.9-1.5-0.30.31.70.8-1.3-0.20.2-1.2-0.2-0.8
Liver weight, right0.20.42.0-1.40.10.0-1.4-0.5-0.4-0.4-0.0-0.2-0.70.3-0.7-0.20.21.30.3-0.50.20.0-0.5-0.4-0.4
Parametrial fat weight0.00.10.20.30.30.40.20.4-0.10.4-0.10.1-0.10.3-0.10.2-0.2-0.10.2-0.1-0.00.20.00.1-0.2
Retroperitoneal fat weight0.20.61.5-1.20.80.9-1.2-0.0-0.90.3-0.70.3-1.10.9-1.00.3-0.31.20.8-1.00.10.5-0.70.1-1.0
Intraocular pressure0.20.30.90.90.40.70.90.6-0.40.6-0.50.60.30.10.30.7-0.7-0.90.2-0.3-0.70.4-0.20.7-0.4
Extensor digitorum longus weight5.622.636.7-1.95.44.9-2.34.1-5.64.2-5.04.0-6.05.8-6.14.0-4.01.75.8-5.6-4.24.9-5.84.1-5.7
Soleus weight0.82.46.0-1.61.41.0-1.70.8-2.20.7-1.20.6-2.31.8-2.30.7-0.71.51.8-2.4-1.01.2-1.90.8-2.0
Tibialis anterior weight3.110.715.1-0.23.73.4-0.43.2-3.93.2-3.53.1-3.73.8-3.63.1-3.10.13.8-3.9-3.23.5-3.83.2-3.8
Tibia length3.29.014.5-3.7-2.9-3.3-3.6-3.81.4-3.83.2-3.80.7-2.10.7-3.73.73.7-2.30.83.4-3.22.1-3.81.8
Number of licking bursts0.60.73.21.8-0.20.21.80.50.70.5-0.00.61.1-0.51.20.5-0.5-1.7-0.40.9-0.10.10.70.30.6
Food consumed during 24 hour testing period0.40.51.8-1.4-0.4-0.8-1.3-0.80.3-0.80.6-0.7-0.4-0.1-0.3-0.80.81.2-0.20.20.7-0.5-0.0-0.80.4
Times rat made contact with spout0.70.83.41.8-0.4-0.21.80.30.90.20.30.21.3-0.71.20.2-0.2-1.7-0.71.1-0.0-0.20.80.30.8
Mean time between licks in bursts2.02.86.1-0.81.71.4-0.91.2-2.31.2-1.71.2-2.11.9-2.11.3-1.30.61.9-2.5-1.61.6-2.01.2-2.1
Mean num. licks in bursts0.10.10.5-0.50.1-0.1-0.50.0-0.4-0.0-0.0-0.2-0.50.3-0.7-0.10.10.50.3-0.4-0.10.0-0.40.1-0.3
Std. dev. time between licks in bursts5.16.18.21.02.72.80.82.7-2.42.7-2.92.8-2.02.5-2.02.8-2.8-1.12.6-2.2-2.82.8-2.62.7-2.6
Water consumed over 24 hours0.60.71.20.80.90.90.81.1-0.51.1-0.91.1-0.40.7-0.41.0-1.0-0.90.8-0.4-0.91.0-0.71.1-0.6
Indifference point 0 sec3.75.910.60.92.32.10.92.5-3.02.4-2.72.6-1.92.2-2.02.7-2.7-1.32.5-3.0-3.32.7-2.72.6-2.7
Indifference point AUC0.60.71.9-0.70.60.3-0.70.2-1.20.3-0.80.6-1.20.8-1.10.5-0.50.40.9-1.4-1.10.7-1.10.4-1.0
Indifference point function ln k0.71.03.61.90.60.91.91.1-0.01.1-0.81.20.60.10.51.1-1.1-1.80.20.3-0.80.80.01.1-0.2
Indifference point function log k0.71.03.61.90.60.91.91.1-0.01.1-0.81.20.60.10.51.1-1.1-1.80.20.3-0.80.80.01.1-0.2
Delay discounting total patch changes 0 sec3.75.910.71.02.32.00.92.5-3.02.4-2.72.7-1.92.2-2.02.7-2.7-1.42.5-3.0-3.32.7-2.72.6-2.7
Delay discounting total patch changes 12 sec0.81.13.5-0.30.80.6-0.30.7-1.70.7-1.10.9-1.11.0-1.11.0-1.00.01.1-1.9-1.51.0-1.30.8-1.4
Delay discounting total patch changes 18 sec1.82.34.90.41.41.20.41.5-1.81.4-1.71.7-1.41.4-1.31.7-1.7-0.81.6-1.8-2.21.7-1.71.5-1.6
Delay discounting total patch changes 24 sec1.21.53.90.21.00.90.11.0-1.81.0-1.41.3-1.21.1-1.11.4-1.4-0.51.2-2.0-1.61.3-1.31.1-1.6
Delay discounting total patch changes 6 sec3.24.98.10.62.11.80.52.2-2.82.1-2.52.4-2.02.2-2.02.5-2.5-1.02.4-2.8-2.92.5-2.42.2-2.5
Delay discounting time to switch 0 sec0.91.42.4-0.1-1.2-1.1-0.0-1.01.4-1.11.5-1.31.2-1.21.2-1.31.30.3-1.31.31.5-1.41.5-1.31.3
Delay discounting water rate 0 sec0.91.52.10.21.31.10.11.3-1.31.3-1.41.2-1.21.3-1.41.2-1.2-0.31.4-1.2-1.51.3-1.41.5-1.3
Delay discounting water rate 12 sec0.30.41.31.10.50.61.10.9-0.10.8-0.50.80.10.30.10.8-0.8-1.10.30.1-0.70.6-0.20.8-0.2
Delay discounting water rate 18 sec0.30.31.21.1-0.10.21.10.10.70.2-0.00.20.9-0.50.80.2-0.2-0.9-0.40.90.1-0.00.60.20.5
Delay discounting water rate 24 sec0.00.00.2-0.30.10.2-0.3-0.0-0.30.00.0-0.1-0.00.1-0.1-0.20.20.40.0-0.30.2-0.10.00.0-0.3
Delay discounting water rate 6 sec0.81.22.61.60.91.21.61.2-0.21.3-1.31.5-0.00.60.01.4-1.4-1.60.70.0-1.21.1-0.51.4-0.4
Locomotor activity0.10.10.4-0.00.20.2-0.10.1-0.50.2-0.30.3-0.20.2-0.20.3-0.3-0.00.2-0.6-0.40.3-0.20.1-0.5
Locomotor testing distance0.10.20.70.7-0.5-0.40.8-0.30.3-0.20.20.10.8-0.70.80.1-0.1-0.8-0.50.2-0.1-0.20.5-0.20.3
Locomotor testing rearing0.40.72.81.70.30.71.70.7-0.10.8-0.50.90.7-0.10.80.9-0.9-1.6-0.00.1-0.60.50.10.7-0.2
Light reinforcement 14.37.811.3-0.33.13.0-0.52.5-3.02.7-3.22.8-3.23.2-3.12.9-2.90.13.3-2.9-2.83.1-3.42.7-3.1
Light reinforcement 20.81.01.9-0.31.10.9-0.30.9-0.80.9-1.21.0-1.41.3-1.31.0-1.00.11.3-0.7-1.01.2-1.31.0-0.8
Reaction time number correct1.42.02.90.31.61.60.21.4-1.51.5-1.71.5-1.21.5-1.31.5-1.5-0.31.6-1.4-1.51.6-1.61.6-1.5
Reaction time mean minus median2.63.35.0-0.5-2.1-2.2-0.4-1.81.8-2.02.2-2.21.4-1.81.5-2.12.10.5-1.91.72.1-2.11.9-1.92.0
Reaction time mean minus median AUC2.12.64.1-0.2-1.8-1.8-0.1-1.52.0-1.61.9-1.91.3-1.61.4-1.71.70.3-1.71.91.9-1.81.8-1.62.0
Reaction time num false alarms3.85.27.8-0.22.72.7-0.42.2-2.62.3-2.42.2-2.62.8-2.62.2-2.20.22.7-2.6-1.92.5-2.42.1-2.7
Reaction time num false alarms AUC4.15.78.5-0.52.82.6-0.72.3-2.72.3-2.62.2-2.82.9-2.82.2-2.20.42.9-2.7-2.12.6-2.62.1-2.9
Reaction time trials correct on left1.42.02.90.31.61.60.21.4-1.51.5-1.71.5-1.21.5-1.31.5-1.5-0.31.6-1.4-1.51.6-1.61.6-1.5
Reaction time trials on left1.31.92.70.31.61.60.21.4-1.41.5-1.61.5-1.21.5-1.31.5-1.5-0.31.5-1.3-1.41.5-1.61.6-1.5
Reaction time mean7.610.415.0-0.9-3.4-3.3-0.8-3.33.6-3.43.7-3.62.8-3.32.8-3.63.61.2-3.53.53.9-3.63.5-3.53.6
Reaction time mean AUC6.99.213.0-0.7-3.2-3.0-0.6-3.03.5-3.13.4-3.32.7-3.12.7-3.33.31.0-3.33.53.6-3.43.4-3.23.5
Median of all reaction times7.410.014.4-0.8-3.3-3.0-0.7-3.23.7-3.23.6-3.43.0-3.22.9-3.43.41.2-3.43.63.8-3.63.5-3.43.5
Reaction time omissions0.70.92.40.8-0.9-0.60.8-0.61.2-0.60.9-0.71.5-1.21.5-0.70.7-0.6-1.21.31.0-0.91.0-0.61.1
Reaction time false alarm rate1.52.23.4-0.41.71.6-0.51.4-1.71.4-1.51.3-1.81.8-1.81.3-1.30.41.8-1.7-1.21.6-1.61.1-1.8
Reaction time premature initiation rate0.00.00.10.2-0.1-0.00.2-0.10.1-0.1-0.1-0.00.3-0.20.10.0-0.0-0.2-0.20.1-0.3-0.10.1-0.10.1
Reaction time premature initiations0.30.40.90.40.70.80.30.6-0.60.7-0.90.8-0.30.5-0.60.8-0.8-0.30.6-0.5-0.90.7-0.70.8-0.6
Std. dev. reaction times6.48.812.4-0.9-3.3-3.4-0.7-3.03.1-3.23.5-3.42.4-3.02.5-3.33.31.0-3.22.93.5-3.43.2-3.23.3
Reaction time trials completed1.31.92.70.31.61.60.21.4-1.41.5-1.61.5-1.21.5-1.31.5-1.5-0.31.5-1.3-1.41.5-1.61.6-1.5
Reaction time trials AUC1.21.82.60.41.51.60.31.4-1.41.5-1.61.5-1.11.4-1.21.5-1.5-0.41.4-1.2-1.41.5-1.51.5-1.4
Social response proportion0.70.81.5-0.2-0.9-0.9-0.2-0.80.9-0.91.2-1.10.7-0.80.9-1.11.10.4-0.90.91.0-1.10.9-0.90.9
Social responses0.00.00.2-0.30.20.1-0.40.1-0.20.1-0.0-0.1-0.30.3-0.3-0.10.10.40.2-0.20.0-0.0-0.30.2-0.2
Social time1.01.33.20.7-1.1-1.00.8-0.71.6-0.81.2-1.01.5-1.31.4-0.90.9-0.6-1.31.80.9-1.11.2-0.71.5
Conditioned locomotion0.00.00.20.1-0.10.10.1-0.10.2-0.00.2-0.20.4-0.20.2-0.10.10.1-0.30.30.4-0.20.3-0.20.1
Cocaine response after cond. corrected0.50.62.3-1.50.60.5-1.5-0.2-0.8-0.0-0.3-0.1-1.10.7-1.1-0.10.11.50.7-0.90.10.2-0.8-0.1-0.8
Cocaine response after cond. not corrected1.11.25.6-2.3-0.2-0.4-2.3-1.1-0.4-0.90.5-1.0-0.90.2-0.9-1.01.02.40.1-0.61.0-0.6-0.2-1.0-0.3
Cocaine response before conditioning0.70.91.5-1.2-0.9-1.1-1.1-1.20.5-1.21.0-1.20.1-0.60.2-1.21.21.1-0.70.21.0-1.00.7-1.20.6
Saline control response0.20.31.41.1-0.1-0.01.20.40.30.3-0.10.30.6-0.30.60.4-0.4-1.2-0.20.4-0.40.10.30.30.3
Condit. Reinf. active minus inactive responses3.24.05.6-1.2-2.1-2.1-1.1-2.31.6-2.32.3-2.41.6-2.11.5-2.32.31.3-2.11.42.3-2.41.9-2.31.7
Condit. Reinf. active-inactive response ratio3.13.24.3-0.4-2.0-2.0-0.3-2.01.8-2.02.0-2.01.8-2.01.7-1.91.90.5-2.01.61.9-2.11.9-1.91.9
Condit. Reinf. active responses0.71.01.7-1.1-1.0-1.0-1.0-1.30.3-1.21.1-1.30.6-0.90.5-1.31.31.2-0.90.11.2-1.20.8-1.30.5
Condit. Reinf. inactive responses0.30.31.5-0.80.40.3-0.80.0-1.00.1-0.20.1-0.80.6-0.70.0-0.00.80.5-1.2-0.10.2-0.50.1-0.9
Condit. Reinf. lever presses0.10.10.2-0.4-0.3-0.4-0.4-0.3-0.2-0.40.3-0.40.1-0.3-0.1-0.30.30.4-0.2-0.40.1-0.40.1-0.3-0.1
Condit. Reinf. lever reinforcers received0.70.91.8-1.2-0.8-0.9-1.2-1.20.1-1.21.0-1.20.3-0.70.3-1.21.21.3-0.8-0.21.2-1.10.6-1.20.3
Pavlov. Cond. lever latency0.20.30.60.50.60.80.40.7-0.20.7-0.60.7-0.40.6-0.20.7-0.7-0.40.5-0.0-0.50.7-0.40.7-0.4
Pavlov. Cond. magazine entry latency0.30.30.6-0.7-0.6-0.7-0.6-0.70.1-0.80.5-0.80.2-0.50.1-0.70.70.6-0.4-0.10.6-0.60.3-0.70.3
Pavlov. Cond. change in total contacts0.91.32.2-0.6-1.3-1.5-0.6-1.30.9-1.41.3-1.30.9-1.20.7-1.31.30.6-1.10.81.1-1.31.0-1.31.1
Pavlov. Cond. index score0.60.71.4-1.0-0.9-1.1-0.9-1.10.2-1.20.9-1.20.4-0.80.2-1.11.10.9-0.70.00.8-1.00.6-1.00.5
Pavlov. Cond. latency score0.60.71.4-1.1-0.9-1.1-1.0-1.10.2-1.10.9-1.20.3-0.70.1-1.01.01.0-0.6-0.00.8-1.00.5-1.00.4
Pavlov. Cond. lever contacts0.40.61.3-0.6-1.0-1.2-0.5-0.90.3-1.00.9-1.10.5-0.80.4-0.90.90.4-0.80.10.7-0.90.7-0.90.6
Pavlov. Cond. magazine entry number0.70.91.60.61.11.30.51.1-0.61.2-1.01.1-0.71.0-0.61.1-1.1-0.50.9-0.5-0.91.1-0.81.0-0.8
Pavlov. Cond. intertrial magazine entries0.81.01.60.61.21.30.61.2-0.91.2-1.11.2-0.71.0-0.61.2-1.2-0.61.0-0.8-1.01.2-0.81.1-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.9-0.7-0.9-0.9-0.8-0.0-0.90.6-0.90.1-0.5-0.1-0.80.80.8-0.4-0.20.5-0.70.3-0.80.2
Pavlov. Cond. response bias0.81.12.2-1.2-1.2-1.5-1.1-1.30.4-1.41.2-1.40.4-0.90.3-1.31.31.0-0.90.11.0-1.20.7-1.30.7
Conditioned reinforcement - actives0.40.40.9-0.3-0.6-0.7-0.3-0.50.9-0.61.0-0.80.3-0.50.4-0.80.80.3-0.60.90.6-0.70.7-0.80.8
Conditioned reinforcement - inactives0.91.01.5-0.8-1.1-1.1-0.8-1.20.9-1.21.2-1.10.6-0.90.5-1.21.20.8-1.00.81.1-1.10.9-1.21.0
Conditioned locomotion2.32.86.6-1.01.91.3-1.11.6-1.61.4-1.51.5-2.52.2-2.61.2-1.20.82.2-1.6-1.51.8-2.01.3-1.6
Intermittent access intake day 1-15 change0.60.61.20.80.71.00.80.8-0.70.9-1.01.00.00.4-0.11.1-1.1-0.80.5-0.6-0.80.8-0.60.9-0.7
Intermittent access intake escalation0.20.20.60.70.30.80.70.4-0.30.5-0.60.60.4-0.00.30.7-0.7-0.60.1-0.2-0.40.4-0.20.5-0.4
Intermittent access intake escalation 20.20.20.70.9-0.10.30.90.10.10.2-0.10.30.8-0.40.70.3-0.3-0.8-0.30.2-0.0-0.00.30.20.1
Intermitt. access day 1 inactive lever presses0.10.10.40.30.30.10.30.6-0.40.4-0.20.2-0.40.4-0.30.3-0.3-0.30.4-0.4-0.40.3-0.30.4-0.3
Intermitt. access day 15 inactive lever presses0.80.91.6-0.1-1.0-1.1-0.0-0.71.2-0.91.3-1.10.8-0.90.7-1.11.10.2-1.01.11.1-1.11.2-1.11.2
Intermitt. access escalation Index0.60.61.40.80.91.20.70.9-0.31.0-0.90.9-0.20.6-0.21.0-1.0-0.60.6-0.1-0.60.8-0.40.9-0.5
Intermittent access day 1 total infusions0.80.92.00.6-1.1-0.90.7-0.81.0-0.71.0-0.61.3-1.21.4-0.80.8-0.5-1.21.00.6-0.91.3-0.61.1
Intermittent access day 15 total infusions0.40.51.71.3-0.30.21.30.00.40.2-0.10.41.2-0.71.20.3-0.3-1.2-0.60.5-0.2-0.00.60.30.3
Intermittent access terminal intake (last 3 days)0.40.41.81.30.00.41.30.40.10.5-0.40.80.9-0.40.90.6-0.6-1.3-0.20.3-0.50.30.30.60.1
Intermittent access total infusions0.50.51.50.9-0.7-0.50.9-0.40.7-0.40.5-0.01.2-1.01.2-0.30.3-0.8-0.90.80.2-0.41.0-0.20.7
Intermittent access day 1 locomotion0.10.10.10.1-0.3-0.30.1-0.20.4-0.20.3-0.10.2-0.20.2-0.30.3-0.1-0.30.40.2-0.20.4-0.10.4
Intermittent access day 15 total locomotion0.00.00.1-0.1-0.1-0.2-0.1-0.0-0.1-0.10.2-0.2-0.10.0-0.1-0.40.40.2-0.0-0.10.1-0.10.10.00.0
Intermittent access total locomotion0.10.10.30.50.20.10.50.4-0.10.3-0.20.30.10.10.10.2-0.2-0.50.1-0.1-0.30.20.00.5-0.1
Intermittent access standard deviation0.20.20.50.30.30.30.20.3-0.70.3-0.60.5-0.10.2-0.10.5-0.5-0.30.3-0.7-0.70.4-0.40.6-0.5
Cocaine induced anxiety3.74.26.4-0.12.52.5-0.21.9-2.12.1-2.32.1-2.22.4-2.22.1-2.10.12.4-1.9-2.02.3-2.52.1-2.3
Post-drug Anxiety1.61.83.50.31.61.90.21.3-1.41.5-1.41.4-1.11.4-1.01.4-1.4-0.21.4-1.3-1.41.4-1.51.4-1.6
Baseline Anxiety3.03.25.00.4-2.0-1.90.5-1.62.0-1.72.0-1.72.1-2.12.2-1.71.7-0.3-2.12.01.6-1.92.2-1.72.0
Lifetime Intake0.10.20.50.5-0.3-0.20.6-0.20.4-0.10.10.20.7-0.50.7-0.10.1-0.5-0.50.4-0.1-0.10.50.10.4
Incentive Sensitization - Responses0.30.30.6-0.1-0.6-0.5-0.1-0.70.4-0.60.6-0.60.7-0.70.7-0.70.70.3-0.70.30.7-0.70.7-0.70.4
Incentive Sensitization - Breakpoint0.20.20.3-0.0-0.5-0.4-0.0-0.50.2-0.40.5-0.40.6-0.50.6-0.50.50.2-0.60.10.5-0.50.5-0.50.2
Progressive ratio test 1 active lever presses0.10.10.4-0.10.20.2-0.1-0.0-0.60.1-0.30.2-0.20.2-0.10.2-0.20.10.2-0.6-0.30.2-0.30.3-0.5
Progressive ratio test 1 breakpoint0.10.10.6-0.10.30.2-0.20.1-0.70.2-0.30.3-0.30.3-0.30.2-0.20.10.3-0.8-0.40.3-0.50.4-0.6
Progressive ratio test 1 inactive lever presses0.00.00.2-0.30.1-0.1-0.30.1-0.20.00.10.0-0.30.2-0.3-0.10.10.30.2-0.3-0.20.1-0.40.1-0.2
Progressive ratio test 2 active lever presses0.20.30.80.2-0.5-0.30.2-0.60.4-0.40.4-0.30.9-0.70.9-0.40.4-0.1-0.70.40.4-0.50.6-0.30.4
Progressive ratio test 2 breakpoint0.20.20.70.7-0.3-0.00.7-0.20.2-0.10.10.10.8-0.50.8-0.10.1-0.5-0.50.30.1-0.20.40.10.2
Progressive ratio test 2 inactive lever presses0.20.20.50.1-0.6-0.50.1-0.40.4-0.50.6-0.50.7-0.60.7-0.50.5-0.0-0.60.30.5-0.60.4-0.50.4
Total sessions with >9 infusions1.31.53.3-1.31.10.9-1.40.5-1.50.6-1.00.8-1.71.4-1.80.6-0.61.21.4-1.6-0.91.1-1.60.7-1.4
Short access day 1 total inactive lever presses0.30.31.3-0.70.50.0-0.70.4-0.50.2-0.2-0.0-1.00.8-1.2-0.00.00.60.7-0.6-0.30.3-0.60.2-0.4
Short access day 10 total inactive lever presses0.40.40.9-0.6-0.6-0.8-0.5-0.60.2-0.70.9-0.90.3-0.50.2-0.90.90.6-0.50.10.8-0.80.5-0.90.4
Short access day 1 total infusions0.20.20.6-0.80.2-0.1-0.8-0.1-0.4-0.1-0.40.2-0.70.4-0.80.1-0.10.50.4-0.5-0.40.3-0.60.1-0.3
Short access day 10 total infusions0.70.72.31.5-0.5-0.21.5-0.10.80.00.40.31.5-0.91.5-0.10.1-1.3-0.91.00.0-0.21.00.20.7
Short access total infusions0.10.10.30.10.20.30.10.1-0.10.2-0.40.6-0.10.2-0.10.3-0.3-0.20.2-0.1-0.40.4-0.20.4-0.2
Short access day 1 locomotion0.30.41.3-0.90.40.1-0.90.2-0.50.1-0.40.3-1.10.7-1.20.1-0.10.70.7-0.5-0.10.5-0.70.3-0.4
Short access day 10 total locomotion0.20.20.8-0.9-0.1-0.2-0.9-0.4-0.2-0.40.3-0.5-0.40.0-0.4-0.50.50.9-0.0-0.40.3-0.30.0-0.5-0.1
Short access total locomotion0.90.92.9-1.40.80.5-1.40.4-1.00.3-0.60.3-1.71.2-1.70.2-0.21.21.1-1.1-0.30.7-1.10.3-0.9
Compulsive drug intake0.10.10.30.50.30.60.40.40.00.4-0.30.30.10.10.10.5-0.5-0.40.20.1-0.20.2-0.20.2-0.2
One hour access (0.3 mA shock)0.60.61.90.9-0.7-0.30.9-0.51.0-0.40.5-0.31.4-1.01.4-0.30.3-0.7-1.01.10.5-0.71.1-0.40.9
One hour access (shock baseline)0.60.71.60.6-0.9-0.70.6-0.71.0-0.60.7-0.51.2-1.11.3-0.60.6-0.5-1.01.00.6-0.71.1-0.40.9
Number of responses in last shaping day0.20.20.40.10.40.40.10.3-0.60.4-0.50.5-0.30.4-0.20.4-0.4-0.10.4-0.5-0.50.5-0.60.6-0.5
Context. condit. distance diff. score1.21.55.92.40.61.12.41.3-0.31.4-0.81.30.80.10.81.3-1.3-2.20.20.0-0.90.80.01.3-0.4
Locomotion velocity, session 10.00.00.10.40.20.40.30.2-0.10.3-0.20.30.20.00.10.2-0.2-0.20.0-0.1-0.00.10.00.2-0.2
Locomotion distance, session 10.30.41.2-0.10.70.7-0.20.6-1.00.6-0.60.6-0.60.7-0.70.5-0.50.20.7-1.1-0.50.6-0.70.5-1.0
Locomotion velocity, session 21.92.23.3-0.31.71.6-0.41.4-1.81.4-1.61.4-1.71.7-1.71.4-1.40.21.7-1.8-1.41.6-1.81.4-1.8
Locomotion distance, session 20.91.22.3-0.61.21.0-0.70.9-1.30.9-1.10.9-1.51.3-1.50.9-0.90.51.4-1.4-1.11.1-1.40.9-1.3
Locomotion velocity, session 30.10.20.30.40.40.50.30.6-0.30.5-0.50.5-0.20.3-0.30.5-0.5-0.40.4-0.2-0.40.5-0.30.5-0.3
Locomotion distance, session 30.40.41.31.10.40.51.10.80.30.7-0.50.80.20.20.00.8-0.8-1.20.30.5-0.70.6-0.10.70.1
Stereotopy head waving bouts, day 30.50.71.20.00.90.9-0.00.8-1.10.8-0.90.8-0.80.9-0.80.8-0.8-0.00.9-1.1-0.70.9-0.70.8-1.1
Stereotopy head waving duration, day 30.10.10.50.10.30.40.00.2-0.70.3-0.20.2-0.10.2-0.10.2-0.20.00.2-0.7-0.00.2-0.10.2-0.6
Locomotion velocity, session 70.70.82.1-1.40.80.5-1.40.2-1.00.2-0.60.2-1.41.1-1.40.2-0.21.31.0-1.1-0.30.5-1.10.2-1.0
Locomotion distance, session 70.50.71.8-1.10.90.8-1.10.4-0.80.4-0.60.3-1.31.1-1.30.3-0.31.11.0-0.8-0.20.6-1.10.3-0.8
Stereotopy head waving bouts, day 70.20.30.50.2-0.5-0.40.3-0.40.6-0.40.5-0.40.7-0.60.7-0.40.4-0.1-0.60.60.6-0.50.7-0.40.6
Stereotopy head waving duration, day 70.60.71.1-0.1-1.0-0.9-0.1-0.90.9-0.91.0-0.90.9-1.00.9-0.90.90.2-1.00.80.9-1.01.1-0.90.9
Locomotion velocity, session 80.30.41.11.00.30.51.00.7-0.20.6-0.60.70.10.20.20.7-0.7-1.00.3-0.1-0.70.6-0.20.7-0.2
Locomotion distance, session 81.11.72.71.41.31.41.41.6-1.01.6-1.41.6-0.41.0-0.51.6-1.6-1.41.1-0.9-1.51.4-1.01.6-1.1
Degree of sensitization distance0.80.83.7-1.90.2-0.0-1.9-0.6-0.6-0.50.2-0.6-1.00.5-0.9-0.60.61.90.4-0.90.6-0.2-0.5-0.6-0.6
Degree of sensitization stereotypy0.40.50.90.5-0.7-0.60.6-0.40.9-0.50.6-0.40.9-0.80.9-0.50.5-0.5-0.80.90.5-0.60.9-0.50.9
Condit. Reinf. active minus inactive responses4.55.06.8-0.7-2.3-2.1-0.6-2.52.3-2.32.5-2.52.1-2.42.1-2.52.51.0-2.52.22.6-2.62.4-2.52.2
Condit. Reinf. active-inactive response ratio2.62.84.0-0.5-1.7-1.5-0.4-1.81.8-1.71.9-1.91.7-1.81.6-1.81.80.7-1.91.82.0-1.91.8-1.81.7
Condit. Reinf. active responses3.34.16.0-1.2-2.0-1.9-1.2-2.31.8-2.22.3-2.41.6-1.91.4-2.42.41.5-2.11.62.5-2.42.0-2.41.8
Condit. Reinf. inactive responses0.20.21.0-0.90.10.0-0.9-0.3-0.4-0.20.2-0.3-0.40.2-0.4-0.40.41.00.1-0.60.4-0.2-0.1-0.4-0.4
Incentive salience index mean3.64.35.7-0.3-2.3-2.1-0.1-2.12.2-2.12.4-2.22.2-2.32.1-2.22.20.5-2.42.12.2-2.42.3-2.22.2
Condit. Reinf. lever presses1.01.32.60.7-1.2-1.00.8-0.81.4-0.81.2-0.91.6-1.41.5-0.90.9-0.6-1.41.51.0-1.11.4-0.91.4
Time in familiar zone, hab. session 10.40.40.91.00.50.80.90.7-0.00.8-0.60.80.10.30.10.8-0.8-0.90.30.2-0.60.6-0.30.8-0.2
Time in novel zone, hab. session 13.73.74.8-0.3-2.2-2.2-0.2-2.02.0-2.02.2-2.01.9-2.11.9-2.02.00.3-2.21.92.0-2.12.2-2.02.1
Total zone transitions, hab. session 10.30.42.1-1.4-0.0-0.4-1.4-0.5-0.1-0.50.2-0.5-0.80.3-0.7-0.50.51.30.2-0.20.2-0.2-0.4-0.5-0.1
Total locomotion distance, hab. session 11.21.77.2-2.7-0.5-0.9-2.7-1.4-0.3-1.30.8-1.3-1.00.1-0.9-1.41.42.6-0.0-0.61.0-0.8-0.2-1.3-0.1
Locomotion velocity, hab. session 10.91.35.8-2.40.3-0.2-2.4-0.6-1.1-0.50.0-0.5-1.60.8-1.5-0.60.62.20.7-1.40.2-0.0-0.9-0.5-0.9
Time in familiar zone, hab. session 20.10.10.30.5-0.2-0.10.5-0.00.4-0.00.10.00.4-0.30.50.0-0.0-0.5-0.30.50.1-0.10.20.00.4
Time in novel zone, hab. session 20.10.10.30.5-0.10.10.50.1-0.00.10.00.10.4-0.20.30.1-0.1-0.4-0.2-0.0-0.0-0.00.30.1-0.0
Total zone transitions, hab. session 20.00.00.20.40.10.10.40.20.10.2-0.10.20.2-0.00.20.2-0.2-0.4-0.00.1-0.30.10.00.20.0
Total locomotion distance, hab. session 20.30.41.4-1.1-0.3-0.4-1.1-0.8-0.2-0.70.6-0.7-0.1-0.2-0.1-0.80.81.2-0.3-0.40.6-0.60.2-0.8-0.1
Locomotion velocity, hab. session 20.30.41.8-1.3-0.2-0.3-1.3-0.7-0.4-0.60.4-0.6-0.40.1-0.3-0.70.71.3-0.1-0.60.5-0.4-0.0-0.7-0.3
Novel to familiar place preference ratio1.51.62.1-0.1-1.5-1.5-0.1-1.41.3-1.31.4-1.31.3-1.41.3-1.31.30.2-1.41.21.2-1.41.4-1.31.4
Novelty place preference1.21.21.90.3-1.3-1.30.3-1.11.1-1.11.2-1.01.3-1.31.4-1.01.0-0.3-1.31.11.0-1.21.3-1.01.2
Time in novel zone, NPP test1.41.52.30.3-1.4-1.30.4-1.21.3-1.11.3-1.11.5-1.51.5-1.11.1-0.3-1.51.21.1-1.31.5-1.11.3
Total zone transitions, NPP test0.30.51.00.10.91.00.10.7-0.60.8-0.80.8-0.60.8-0.60.7-0.7-0.00.8-0.5-0.70.8-0.70.7-0.8
Total locomotion distance, NPP test0.20.31.2-1.1-0.1-0.4-1.1-0.5-0.4-0.50.2-0.4-0.50.1-0.5-0.50.51.00.1-0.60.2-0.2-0.1-0.5-0.2
Locomotion velocity, NPP test0.20.31.0-1.00.30.0-1.0-0.1-0.7-0.1-0.20.0-0.90.5-0.9-0.00.00.90.5-0.9-0.30.2-0.6-0.1-0.6
Pavlov. Cond. lever latency2.63.34.8-0.52.01.9-0.61.6-2.11.7-2.01.8-2.22.2-2.11.7-1.70.32.2-2.1-1.82.0-2.21.7-2.1
Pavlov. Cond. magazine entry latency2.73.44.9-0.3-2.0-1.9-0.2-1.92.2-1.92.1-1.91.9-2.01.8-1.91.90.4-2.12.22.0-2.12.0-1.92.1
Pavlov. Cond. change in total contacts1.92.03.00.2-1.5-1.30.3-1.41.5-1.31.6-1.41.7-1.71.7-1.41.40.0-1.71.41.7-1.61.7-1.41.5
Pavlov. Cond. index score2.73.55.60.7-2.1-1.80.8-1.62.3-1.62.0-1.62.4-2.32.4-1.61.6-0.5-2.32.31.8-1.92.3-1.62.2
Pavlov. Cond. latency score2.83.65.40.5-2.1-1.90.7-1.72.3-1.72.0-1.72.3-2.32.3-1.71.7-0.4-2.32.31.8-2.02.3-1.72.3
Pavlov. Cond. lever contacts1.61.93.91.1-1.5-1.21.2-0.91.5-0.91.4-1.02.0-1.71.9-0.90.9-1.0-1.71.51.1-1.31.7-0.91.5
Pavlov. Cond. magazine entry number4.55.77.9-0.12.62.4-0.22.4-2.82.3-2.62.3-2.62.7-2.62.3-2.3-0.12.8-2.8-2.52.6-2.72.3-2.7
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.20.40.5-0.30.1-0.60.2-0.30.2-0.30.3-0.20.2-0.20.30.3-0.6-0.10.2-0.20.2-0.6
Pavlov. Cond. lever-magazine prob. diff.2.22.84.50.6-1.8-1.60.7-1.52.0-1.41.8-1.52.1-2.02.1-1.41.4-0.4-2.02.01.6-1.72.0-1.41.9
Pavlov. Cond. response bias2.53.05.10.7-1.9-1.60.8-1.52.0-1.51.8-1.52.3-2.12.2-1.51.5-0.6-2.12.11.7-1.82.1-1.52.0
Bone: apparent density2.23.66.1-0.1-2.4-2.50.1-2.01.9-2.12.2-2.01.9-2.21.9-2.02.0-0.0-2.21.71.7-2.12.2-2.02.1
Bone surface0.50.91.8-1.3-1.0-1.3-1.3-1.20.5-1.31.0-1.2-0.1-0.60.0-1.21.21.2-0.60.20.9-0.90.5-1.30.7
Bone volume1.72.94.9-1.1-2.0-2.2-1.0-2.01.5-2.11.9-2.01.0-1.61.1-2.02.01.0-1.71.21.7-1.91.7-2.11.7
Bone: connectivity density0.20.30.90.0-0.8-1.00.1-0.60.5-0.70.7-0.50.5-0.70.5-0.60.6-0.2-0.70.40.4-0.60.7-0.60.7
Bone: cortical apparent density6.28.011.50.53.33.40.33.0-2.53.1-3.33.1-2.83.2-2.83.1-3.1-0.63.2-2.3-2.83.3-3.13.0-2.9
Bone: cortical area0.40.72.1-1.40.50.3-1.5-0.1-1.1-0.1-0.3-0.0-1.10.7-1.1-0.00.01.40.6-1.40.00.2-0.7-0.2-1.0
Bone: cortical porosity1.71.83.2-0.0-1.6-1.80.1-1.31.6-1.41.5-1.41.3-1.51.3-1.41.4-0.1-1.51.61.0-1.51.4-1.21.7
Bone: cortical porosity2.02.24.1-0.4-1.8-2.0-0.3-1.51.5-1.71.7-1.71.2-1.61.2-1.61.60.3-1.61.41.2-1.71.4-1.51.7
Bone: cortical thickness1.42.43.50.21.71.70.11.5-1.91.6-1.71.7-1.41.6-1.51.6-1.6-0.21.7-1.9-1.51.7-1.61.5-1.9
Bone: cortical thickness0.10.10.4-0.60.0-0.0-0.6-0.2-0.2-0.2-0.0-0.1-0.30.1-0.4-0.10.10.60.1-0.30.10.0-0.2-0.2-0.2
Bone: cortical tissue density6.17.911.30.53.33.40.33.0-2.53.1-3.33.1-2.83.2-2.83.1-3.1-0.63.2-2.2-2.83.3-3.12.9-2.8
Bone: elastic displacement0.70.82.31.5-0.7-0.51.5-0.01.2-0.10.40.01.3-1.01.3-0.00.0-1.5-0.81.40.0-0.40.8-0.01.1
Bone: elastic work1.41.82.4-0.6-1.5-1.5-0.6-1.51.5-1.51.5-1.51.1-1.41.0-1.51.50.6-1.41.51.4-1.51.3-1.51.5
Bone: endosteal estimation2.86.110.1-3.0-2.4-2.8-2.9-3.11.2-3.12.7-3.20.6-1.80.7-3.13.12.9-1.90.72.8-2.71.7-3.11.5
Bone: endosteal perimeter1.22.54.3-2.0-1.4-1.6-1.9-2.00.7-1.91.7-2.00.4-1.10.5-2.02.02.1-1.20.41.9-1.71.1-2.00.8
Bone: final force0.91.45.8-2.4-0.4-0.7-2.4-1.2-0.5-1.10.7-1.2-0.80.1-0.9-1.21.22.4-0.0-0.81.0-0.7-0.1-1.2-0.3
Bone: final moment0.61.04.3-2.1-0.1-0.4-2.1-0.8-0.7-0.80.4-0.8-1.00.3-1.0-0.80.82.00.2-1.10.6-0.4-0.3-0.9-0.5
Bone: marrow area2.75.79.4-2.9-2.3-2.7-2.8-3.01.1-3.02.6-3.10.6-1.70.6-3.03.02.9-1.80.62.7-2.61.6-3.01.4
Bone: maximum diameter0.10.20.8-0.80.20.1-0.8-0.1-0.7-0.1-0.0-0.1-0.50.3-0.5-0.10.10.80.3-0.90.10.0-0.3-0.2-0.6
Bone: maximum force1.62.89.4-3.1-1.1-1.6-3.0-2.0-0.0-2.01.4-2.0-0.6-0.4-0.6-1.91.92.9-0.6-0.51.6-1.40.4-2.00.3
Bone: maximum moment1.11.97.1-2.7-0.8-1.3-2.6-1.5-0.3-1.61.0-1.5-0.7-0.2-0.8-1.51.52.5-0.3-0.71.2-1.10.2-1.60.0
Bone: minimum diameter0.71.24.9-2.2-0.4-0.8-2.2-1.1-0.7-1.10.6-1.1-0.90.1-0.8-1.11.12.10.0-1.10.7-0.6-0.2-1.1-0.4
Bone: periosteal estimation1.53.17.2-2.7-1.4-1.8-2.6-2.20.2-2.21.8-2.2-0.0-0.90.0-2.22.22.6-1.0-0.31.9-1.80.9-2.20.5
Bone: periosteal perimeter0.61.12.3-1.5-0.8-1.0-1.4-1.30.2-1.31.1-1.30.1-0.60.2-1.31.31.5-0.7-0.11.2-1.10.7-1.40.3
Bone: post-yield work1.11.53.1-1.8-1.0-1.3-1.7-1.50.5-1.51.2-1.50.0-0.6-0.0-1.51.51.7-0.70.21.3-1.20.7-1.50.6
Bone: stiffness1.52.39.2-3.0-0.7-1.1-3.0-1.7-0.4-1.61.0-1.6-0.9-0.1-0.9-1.61.63.0-0.2-0.91.4-1.00.1-1.7-0.2
Bone: tissue strength0.00.00.2-0.40.1-0.0-0.40.0-0.0-0.0-0.1-0.0-0.40.2-0.4-0.00.00.30.2-0.0-0.10.1-0.2-0.0-0.0
Bone: trabecular number1.01.62.7-0.5-1.5-1.7-0.4-1.41.2-1.51.4-1.41.0-1.31.0-1.41.40.4-1.41.01.2-1.41.4-1.51.3
Bone: trabecular spacing0.40.51.0-0.60.91.0-0.70.4-0.60.6-0.70.4-0.90.9-1.00.4-0.40.80.8-0.6-0.20.6-0.80.5-0.8
Bone: trabecular thickness3.64.36.30.4-2.5-2.40.6-2.02.3-2.12.3-1.92.4-2.52.4-1.91.9-0.4-2.52.21.8-2.22.5-2.02.5
Bone: trabecular tissue density0.20.21.0-0.9-0.2-0.1-0.9-0.60.1-0.50.4-0.6-0.1-0.1-0.1-0.50.51.0-0.20.00.7-0.40.2-0.60.1
Breakpoint value in progressive ratio session0.80.91.5-0.1-0.9-0.5-0.1-1.01.0-0.91.1-1.01.1-1.01.1-0.90.90.3-1.11.01.2-1.11.2-1.00.9
Distance traveled before self-admin4.54.87.8-2.2-2.2-2.7-2.1-2.51.5-2.72.6-2.80.8-1.60.7-2.82.82.1-1.91.12.4-2.41.8-2.81.7
Distance traveled after self-admin1.01.12.4-1.2-0.9-1.1-1.1-1.10.6-1.21.4-1.60.3-0.60.2-1.41.41.2-0.80.41.2-1.30.7-1.40.7
Delta time in closed arm before/after self-admin1.21.11.7-0.31.11.0-0.40.8-1.30.9-1.31.0-1.21.2-1.21.0-1.00.21.2-1.3-1.21.1-1.31.0-1.3
Delta time in open arm before/after self-admin3.73.55.2-0.2-2.2-2.2-0.1-1.82.0-2.02.3-2.11.6-2.01.7-2.02.00.2-2.11.82.0-2.12.1-2.02.1
Diff in mean of infusions in LGA sessions1.61.82.60.0-1.5-1.30.1-1.31.4-1.31.5-1.41.5-1.61.5-1.41.40.1-1.61.41.4-1.51.6-1.41.4
Extinction: sum of active levers before priming1.51.52.6-0.6-1.2-1.1-0.5-1.41.1-1.31.5-1.41.0-1.21.1-1.41.40.7-1.31.01.6-1.41.3-1.41.1
Active lever presses in extinction session 60.80.71.50.5-0.8-0.50.6-0.61.2-0.60.9-0.71.1-1.01.2-0.60.6-0.4-1.01.20.9-0.81.1-0.71.0
Delta distance traveled before/after self-admin0.70.71.60.71.01.30.61.1-0.61.1-0.80.8-0.50.9-0.51.0-1.0-0.50.8-0.5-0.80.8-0.81.0-0.8
Delta ambulatory time before/after self-admin0.90.92.10.71.21.50.61.1-0.81.2-1.00.9-0.50.9-0.51.2-1.2-0.60.9-0.6-1.00.9-0.91.2-1.0
Time in closed arm before self-admin2.42.74.2-0.6-1.9-2.1-0.5-1.91.5-1.91.9-1.81.4-1.81.4-1.81.80.6-1.81.31.6-1.91.6-1.91.7
Time in closed arm after self-admin0.20.20.6-0.8-0.3-0.4-0.7-0.6-0.1-0.50.3-0.4-0.0-0.2-0.1-0.40.40.7-0.2-0.20.2-0.4-0.0-0.5-0.0
Time in open arm before self-admin2.42.55.00.42.02.20.31.6-1.51.8-1.91.8-1.21.7-1.31.7-1.7-0.21.7-1.3-1.61.8-1.61.8-1.8
Time in open arm after self-admin2.32.53.6-0.5-1.8-1.8-0.4-1.61.6-1.71.9-1.81.3-1.61.3-1.81.80.6-1.71.51.8-1.71.8-1.81.7
Sum of active levers in priming session hrs 5-62.12.13.5-0.6-1.4-1.1-0.5-1.71.3-1.51.7-1.81.3-1.41.4-1.61.60.8-1.61.21.9-1.81.5-1.61.3
Time to tail flick, vehicle, before self-admin0.50.50.90.70.70.80.61.0-0.50.9-0.70.9-0.20.6-0.30.8-0.8-0.70.6-0.4-0.70.8-0.60.9-0.6
Time to tail flick, vehicle, after self-admin0.20.20.60.1-0.5-0.30.1-0.70.6-0.40.4-0.40.8-0.60.8-0.40.4-0.0-0.60.60.4-0.50.6-0.40.5
Time to tail flick, test, before self-admin1.41.32.2-0.31.41.4-0.41.2-1.31.1-1.10.9-1.51.5-1.41.0-1.00.41.4-1.2-1.01.2-1.41.0-1.4
Time to tail flick, test, after self-admin2.02.13.3-0.21.61.3-0.21.4-1.71.4-1.51.4-1.71.7-1.61.3-1.30.01.7-1.7-1.71.6-1.81.4-1.7
Delta time to tail flick, vehicle, before/after SA0.80.71.5-0.6-0.9-0.9-0.5-1.20.7-1.00.9-1.00.7-0.90.7-1.01.00.6-0.90.60.8-1.00.8-1.00.8
Delta time to tail flick, test, before/after SA0.10.10.50.4-0.1-0.30.40.2-0.10.1-0.20.40.1-0.10.10.2-0.2-0.70.1-0.1-0.50.3-0.10.30.1
Ambulatory time before self-admin3.73.86.0-1.9-2.0-2.4-1.8-2.21.7-2.32.3-2.40.6-1.40.6-2.52.51.8-1.61.42.2-2.11.7-2.41.8
Ambulatory time after self-admin0.20.20.7-0.8-0.1-0.2-0.8-0.3-0.2-0.40.4-0.6-0.30.1-0.3-0.50.50.8-0.0-0.30.4-0.4-0.1-0.5-0.1
Total heroin consumption0.81.01.70.5-1.2-1.10.5-0.81.2-0.91.1-0.91.2-1.21.3-0.80.8-0.5-1.21.20.9-1.01.3-0.91.2
Area under the delay curve0.00.00.10.3-0.10.00.3-0.10.10.00.10.30.4-0.20.3-0.00.0-0.2-0.20.20.1-0.10.2-0.00.1
Delay disc. indifference point, 0s delay0.00.00.10.2-0.3-0.30.3-0.10.1-0.10.2-0.10.2-0.30.3-0.10.1-0.3-0.20.1-0.1-0.20.1-0.10.2
Delay disc. indifference point, 16s delay0.50.50.90.0-0.8-0.60.0-0.80.7-0.70.8-0.40.9-0.90.9-0.80.80.1-0.90.70.7-0.80.9-0.80.7
Delay disc. indifference point, 2s delay0.00.00.0-0.1-0.1-0.2-0.1-0.1-0.0-0.10.00.1-0.0-0.1-0.1-0.00.00.0-0.0-0.0-0.1-0.10.0-0.00.0
Delay disc. indifference point, 24s delay0.20.20.90.90.00.30.90.20.40.3-0.00.60.6-0.20.60.2-0.2-0.8-0.30.60.00.10.30.20.3
Delay disc. indifference point, 4s delay0.30.30.70.20.60.60.20.6-0.70.6-0.60.8-0.40.5-0.50.6-0.6-0.20.6-0.7-0.70.5-0.70.6-0.7
Delay disc. indifference point, 8s delay0.30.30.6-0.3-0.5-0.4-0.3-0.80.4-0.60.5-0.20.6-0.60.5-0.70.70.4-0.60.30.8-0.60.5-0.70.4
Delay discount exponential model param0.10.10.2-0.40.1-0.1-0.40.1-0.2-0.1-0.1-0.4-0.50.3-0.4-0.00.00.30.2-0.2-0.10.1-0.2-0.0-0.2
Delay discount hyperbolic model param0.00.00.2-0.3-0.1-0.2-0.3-0.10.1-0.20.1-0.5-0.20.0-0.1-0.20.20.30.00.00.1-0.10.0-0.20.1
Fecal boli incidents, locomotor time 10.10.10.30.30.10.10.30.20.40.2-0.20.3-0.00.1-0.00.3-0.3-0.40.10.6-0.40.2-0.00.30.3
Change in fecal boli incidents, locomotor task0.10.10.40.6-0.00.10.60.2-0.00.20.00.20.4-0.20.30.2-0.2-0.5-0.20.0-0.10.00.20.2-0.1
Time >=10cm from walls, locomotor time 10.50.51.7-1.20.50.3-1.3-0.1-1.00.0-0.4-0.0-0.90.6-0.7-0.00.01.20.6-1.2-0.10.2-0.8-0.0-0.9
Bouts of movement, locomotor time 11.01.11.70.61.11.10.61.3-1.01.2-1.11.2-0.81.0-1.01.2-1.2-0.71.1-1.0-1.11.2-0.91.2-1.0
Total resting periods, locomotor time 11.51.62.30.41.41.30.41.5-1.31.4-1.41.4-1.21.4-1.31.4-1.4-0.51.4-1.3-1.41.5-1.21.4-1.3
Rest time, locomotor task time 10.50.61.31.10.60.61.00.9-0.40.9-0.70.9-0.20.5-0.10.9-0.9-1.10.5-0.2-1.00.8-0.30.9-0.4
Distance moved, locomotor task time 10.10.10.4-0.3-0.2-0.0-0.3-0.50.2-0.30.4-0.50.5-0.40.4-0.50.50.5-0.40.10.7-0.50.3-0.50.1
Vertical activity count, locomotor time 10.00.00.2-0.40.10.1-0.4-0.1-0.3-0.1-0.0-0.1-0.10.1-0.2-0.10.10.50.1-0.30.2-0.1-0.2-0.1-0.2
Time >=10cm from walls, locomotor time 21.51.62.50.1-1.5-1.40.2-1.31.3-1.31.4-1.21.5-1.61.6-1.21.2-0.1-1.51.31.2-1.41.3-1.21.4
Bouts of movement, locomotor time 23.13.35.10.72.12.30.52.0-1.92.1-2.02.0-1.51.9-1.72.0-2.0-0.62.0-1.8-1.82.0-1.82.0-2.0
Total resting periods, locomotor time 23.13.44.70.82.12.20.72.1-1.92.1-2.02.1-1.51.9-1.62.1-2.1-0.81.9-1.7-1.92.1-1.82.1-2.0
Rest time, locomotor task time 21.01.23.11.20.90.81.11.3-0.71.2-1.11.3-0.50.8-0.41.3-1.3-1.30.9-0.5-1.81.2-0.81.3-0.7
Distance moved, locomotor task time 20.60.61.5-0.7-0.7-0.6-0.7-1.00.4-0.90.8-1.00.6-0.70.5-1.01.00.9-0.80.31.2-1.00.6-1.00.4
Vertical activity count, locomotor time 20.00.00.10.20.20.40.20.1-0.10.2-0.10.10.2-0.00.00.1-0.1-0.1-0.0-0.00.20.0-0.10.1-0.2
Weight adjusted by age0.70.73.3-1.8-0.1-0.4-1.8-0.8-0.4-0.70.4-0.7-0.90.3-0.8-0.90.91.80.1-0.70.5-0.4-0.3-0.8-0.3
Seeking ratio, delayed vs. immediate footshock1.92.23.3-1.0-1.6-1.7-1.0-1.61.2-1.81.8-1.81.0-1.40.8-1.81.81.1-1.51.01.5-1.71.4-1.81.3
Locomotion in novel chamber2.12.65.1-1.21.71.3-1.31.0-2.11.1-1.51.1-2.21.9-2.31.0-1.01.11.9-2.2-1.31.5-2.11.1-2.0
Locomotion in novel chamber post-restriction1.61.94.7-1.21.41.0-1.31.0-1.80.8-1.10.7-2.11.7-2.20.7-0.71.11.6-1.9-0.91.2-1.50.8-1.7
Progressive ratio0.30.30.8-0.50.60.9-0.60.2-0.80.4-0.40.2-0.50.6-0.60.3-0.30.70.5-0.9-0.00.3-0.50.2-0.9
Food seeking constrained by brief footshock0.30.41.3-1.10.50.5-1.1-0.2-0.90.0-0.3-0.1-0.80.6-0.80.1-0.11.10.5-1.00.10.2-0.8-0.0-0.9
Seeking ratio, punishment vs. effort0.00.10.2-0.5-0.1-0.4-0.4-0.2-0.0-0.30.0-0.2-0.30.0-0.2-0.20.20.30.1-0.1-0.0-0.0-0.2-0.20.1
Run reversals in cocaine runway, females0.50.51.3-1.10.60.4-1.10.1-0.80.2-0.40.2-1.10.8-1.10.1-0.11.00.7-0.9-0.20.4-0.80.1-0.8
Run reversals in cocaine runway, males1.11.01.7-0.61.21.1-0.70.8-1.20.8-1.00.8-1.31.3-1.30.8-0.80.61.2-1.2-0.81.0-1.30.8-1.3
Latency to leave start box in cocaine runway5.45.98.00.92.72.60.72.8-2.32.7-2.82.7-2.32.7-2.32.8-2.8-1.12.7-2.1-2.62.8-2.42.7-2.4
Latency to leave start box in cocaine runway, F3.23.55.31.21.91.71.12.3-1.62.1-2.12.2-1.51.8-1.52.3-2.3-1.52.0-1.4-2.32.2-1.82.2-1.6
Latency to leave start box in cocaine runway, M2.62.54.2-0.81.91.8-0.91.3-1.81.4-1.71.3-2.02.0-2.01.3-1.30.81.9-1.8-1.11.6-1.61.3-1.9
Cd content in liver0.70.72.2-1.5-0.5-0.7-1.5-1.00.1-1.00.7-1.0-0.2-0.3-0.2-1.01.01.5-0.4-0.11.0-0.80.3-1.00.2
Co content in liver0.80.92.21.1-0.9-0.61.1-0.51.3-0.40.8-0.51.5-1.11.5-0.50.5-0.9-1.11.50.7-0.81.2-0.51.2
Cu content in liver2.22.63.80.0-1.8-1.50.1-1.71.9-1.61.7-1.61.9-1.91.8-1.61.60.2-1.91.91.7-1.81.9-1.71.8
Fe content in liver3.13.75.0-0.2-2.2-2.0-0.1-2.02.1-2.02.1-2.02.0-2.22.0-2.02.00.3-2.22.02.2-2.12.2-2.02.1
K content in liver1.41.42.4-0.41.10.8-0.41.0-1.50.9-1.21.1-1.51.3-1.51.1-1.10.01.4-1.6-1.41.3-1.51.0-1.3
Mg content in liver0.91.01.50.20.90.80.21.0-1.20.9-1.11.1-1.01.0-1.01.1-1.1-0.41.1-1.2-1.21.1-1.11.0-1.1
Mn content in liver0.40.51.91.20.30.21.20.9-0.50.7-0.50.80.10.20.10.8-0.8-1.40.3-0.5-0.90.6-0.30.8-0.3
Na content in liver0.10.10.20.20.20.10.20.3-0.40.2-0.30.4-0.20.2-0.20.4-0.4-0.30.3-0.5-0.40.3-0.30.3-0.3
Rb content in liver1.31.63.0-1.01.51.4-1.10.9-1.51.0-1.20.9-1.71.6-1.70.9-0.91.01.5-1.5-0.71.2-1.50.9-1.6
Se content in liver0.10.10.2-0.10.30.1-0.10.3-0.20.2-0.30.3-0.40.3-0.40.3-0.30.00.4-0.2-0.50.3-0.40.3-0.2
Sr content in liver0.10.10.30.50.40.50.50.4-0.20.5-0.30.40.10.20.10.4-0.4-0.40.2-0.1-0.40.3-0.20.4-0.3
Zn content in liver0.80.81.20.11.01.10.10.9-1.10.9-1.11.0-0.80.9-0.81.0-1.0-0.11.0-1.0-1.01.0-1.00.9-1.1