Hub : Genes

ENSRNOG00000028430

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr10:83271000:83276800 0.02 0.02 3.6e-03 0.02 0.02 0.01 0.02 1.1e-03 6.4e-03 7.9e-03 5.5e-03
2 Adipose intron excision ratio chr10:83271000:83279092 0.02 0.02 1.9e-03 0.01 0.02 0.01 0.01 2.1e-02 2.8e-03 8.8e-03 1.1e-02
3 Adipose mRNA stability ENSRNOG00000028430 0.06 0.04 1.2e-09 0.07 0.08 0.07 0.06 2.1e-08 8.8e-09 3.0e-08 1.2e-07
4 BLA gene expression ENSRNOG00000028430 0.07 0.05 2.1e-03 0.03 0.03 0.02 0.03 6.8e-03 9.3e-03 2.0e-02 1.2e-02
5 Brain gene expression ENSRNOG00000028430 0.04 0.03 6.2e-03 -0 0 -0 -0 7.0e-01 2.3e-01 6.5e-01 8.5e-01
6 Brain intron excision ratio chr10:83271000:83276800 0.08 0.06 1.1e-04 0.05 0.04 0.04 0.04 4.5e-05 1.5e-04 6.0e-05 1.3e-04
7 Brain intron excision ratio chr10:83271000:83279092 0.09 0.05 1.4e-10 0.12 0.12 0.12 0.12 1.7e-11 3.6e-11 1.8e-11 1.9e-11
8 Brain intron excision ratio chr10:83277179:83279092 0.03 0.02 1.9e-03 0.03 0.03 0.02 0.02 9.6e-04 1.5e-03 8.6e-03 2.7e-03
9 Brain mRNA stability ENSRNOG00000028430 0.12 0.08 3.2e-12 0.14 0.13 0.12 0.13 1.0e-12 3.6e-12 1.3e-11 7.0e-12
10 LHb mRNA stability ENSRNOG00000028430 0.37 0.34 6.7e-03 0.11 -0.01 0.08 0.09 1.7e-03 4.8e-01 6.7e-03 3.1e-03
11 Liver intron excision ratio chr10:83271000:83276800 0.02 0.01 8.6e-03 0.01 0.01 0.01 0 4.4e-02 1.7e-02 2.6e-02 1.2e-01
12 Liver intron excision ratio chr10:83271000:83279092 0.12 0.07 0.0e+00 0.14 0.15 0.15 0.16 4.3e-15 9.0e-17 6.0e-16 5.6e-17
13 Liver intron excision ratio chr10:83277013:83279092 0.06 0.08 6.8e-04 0.03 0.02 0.03 0.03 4.8e-04 1.2e-03 2.8e-04 2.3e-04
14 Liver mRNA stability ENSRNOG00000028430 0.07 0.05 2.0e-10 0.06 0.07 0.08 0.08 6.5e-07 4.9e-08 2.8e-09 1.3e-09
15 NAcc intron excision ratio chr10:83271000:83279092 0.04 0.03 4.5e-03 0.02 0.03 0.03 0.02 5.9e-03 4.8e-03 5.6e-03 8.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail1.85.99.02.0-2.8-2.3-2.3-2.22.4-2.32.2-2.3-2.32.8-2.52.3-3.0-2.5
BMI without tail0.10.10.50.5-0.4-0.4-0.1-0.40.3-0.30.7-0.1-0.30.4-0.10.1-0.4-0.4
Body weight6.025.430.94.8-5.5-5.0-4.8-4.95.2-5.25.0-4.8-5.25.4-4.84.3-5.6-5.1
Epididymis fat weight0.30.61.30.5-0.9-0.8-0.6-0.71.1-1.10.8-0.6-1.10.9-0.50.4-0.8-0.7
Glucose0.50.71.2-0.80.70.91.11.0-1.01.1-1.01.11.1-0.70.2-0.10.40.8
Heart weight3.44.96.12.0-2.4-2.2-2.0-2.12.3-2.32.2-2.0-2.32.3-2.12.3-2.5-2.2
Left kidney weight1.95.47.72.8-2.2-2.5-2.3-2.62.6-2.52.8-2.3-2.52.3-1.51.2-1.9-2.3
Right kidney weight0.41.11.81.3-1.0-1.0-1.0-1.01.2-1.11.3-1.0-1.21.0-0.60.5-0.9-0.9
Tail length0.72.34.82.0-1.3-1.6-1.3-1.61.6-1.72.2-1.3-1.71.3-0.80.8-1.1-1.4
Length with tail4.315.818.94.3-4.0-4.1-3.8-4.04.2-4.34.3-3.8-4.34.0-3.43.1-3.9-4.0
Length without tail4.910.712.53.0-3.5-3.2-3.3-3.13.5-3.52.9-3.3-3.53.4-3.22.8-3.5-3.3
Liver weight, left0.10.10.40.5-0.2-0.3-0.4-0.30.4-0.40.6-0.4-0.30.2-0.10.1-0.3-0.2
Liver weight, right0.10.20.8-0.20.40.30.50.3-0.10.1-0.20.50.1-0.50.9-0.90.50.5
Parametrial fat weight0.71.44.5-1.21.11.11.01.2-0.70.7-1.01.00.8-1.21.7-2.11.21.3
Retroperitoneal fat weight0.10.20.70.3-0.6-0.5-0.3-0.50.8-0.70.4-0.3-0.70.6-0.1-0.3-0.3-0.4
Intraocular pressure1.82.54.01.2-1.7-1.6-1.6-1.61.4-1.51.2-1.6-1.51.7-2.01.9-1.8-1.7
Extensor digitorum longus weight8.935.839.75.7-6.1-6.0-6.2-6.05.7-5.75.6-6.2-5.76.1-6.36.3-6.1-6.2
Soleus weight0.30.81.8-1.10.51.10.51.1-1.31.3-1.10.51.3-0.6-0.20.20.20.8
Tibialis anterior weight1.44.96.22.2-2.3-2.1-2.3-2.01.9-2.02.1-2.3-2.02.3-2.42.2-2.5-2.2
Tibia length1.13.15.41.4-2.1-1.4-1.8-1.31.4-1.41.4-1.8-1.42.0-2.32.2-2.3-1.7
Number of licking bursts0.50.61.0-1.00.50.90.70.9-0.90.9-0.80.70.9-0.60.3-0.20.30.7
Food consumed during 24 hour testing period0.81.01.61.3-1.1-0.9-1.0-0.90.9-1.01.1-1.0-1.01.1-1.00.7-1.1-1.0
Times rat made contact with spout1.21.41.7-1.01.11.31.11.2-1.21.3-1.11.11.3-1.11.2-1.31.11.2
Mean time between licks in bursts1.41.92.41.3-1.5-1.4-1.4-1.31.4-1.31.5-1.4-1.31.5-1.30.9-1.3-1.4
Mean num. licks in bursts0.10.10.50.10.30.10.10.1-0.00.0-0.10.10.0-0.30.6-0.70.40.2
Std. dev. time between licks in bursts0.10.20.40.6-0.5-0.4-0.5-0.40.5-0.40.3-0.5-0.40.5-0.20.1-0.4-0.4
Water consumed over 24 hours0.00.00.1-0.0-0.10.0-0.20.0-0.10.1-0.0-0.20.10.1-0.20.2-0.2-0.1
Indifference point 0 sec1.83.05.0-1.41.81.52.21.4-1.51.4-1.62.21.4-1.81.8-1.82.01.6
Indifference point AUC0.10.10.20.4-0.1-0.10.4-0.00.1-0.20.40.4-0.10.1-0.20.5-0.1-0.1
Indifference point function ln k0.00.00.1-0.10.1-0.00.1-0.1-0.10.2-0.30.10.1-0.10.1-0.00.2-0.0
Indifference point function log k0.00.00.1-0.10.1-0.00.1-0.1-0.10.2-0.30.10.1-0.10.1-0.00.2-0.0
Delay discounting total patch changes 0 sec1.32.14.2-1.11.51.22.11.1-1.21.2-1.32.11.2-1.51.6-1.51.71.4
Delay discounting total patch changes 12 sec5.06.68.3-2.22.62.62.92.6-2.42.4-2.32.92.5-2.72.6-2.42.62.7
Delay discounting total patch changes 18 sec0.60.81.7-0.51.00.91.30.8-0.90.7-0.41.30.7-0.90.8-0.70.90.9
Delay discounting total patch changes 24 sec2.02.53.6-1.11.71.71.71.6-1.91.8-1.11.71.9-1.71.3-0.71.61.6
Delay discounting total patch changes 6 sec2.03.04.8-1.31.81.62.21.6-1.61.4-1.22.21.4-1.82.1-1.91.91.8
Delay discounting time to switch 0 sec0.00.10.2-0.40.30.2-0.00.2-0.20.2-0.2-0.00.3-0.30.3-0.30.20.3
Delay discounting water rate 0 sec0.00.00.20.3-0.0-0.10.2-0.10.1-0.1-0.00.2-0.20.00.3-0.40.10.0
Delay discounting water rate 12 sec0.20.40.90.9-0.5-0.6-0.5-0.60.5-0.50.8-0.5-0.60.5-0.60.6-0.5-0.6
Delay discounting water rate 18 sec0.40.60.9-0.70.70.80.80.8-0.80.9-0.70.80.9-0.70.7-0.70.60.8
Delay discounting water rate 24 sec0.40.61.6-0.60.70.60.70.7-0.50.6-0.70.70.6-0.71.1-1.30.70.8
Delay discounting water rate 6 sec1.11.62.7-1.01.31.21.41.2-1.11.0-1.01.41.0-1.31.6-1.61.31.3
Locomotor activity0.50.81.3-0.90.81.10.81.1-1.11.1-1.00.81.1-0.90.7-0.60.61.0
Locomotor testing distance2.74.46.1-2.52.12.22.02.1-2.22.2-2.22.02.2-2.11.8-1.91.92.1
Locomotor testing rearing6.410.112.3-3.13.32.93.52.8-2.92.8-3.03.52.9-3.23.5-3.53.53.1
Light reinforcement 12.44.37.1-2.02.12.02.11.9-1.81.7-1.92.11.7-2.12.7-2.52.22.2
Light reinforcement 20.71.01.2-1.10.81.11.01.1-0.90.9-0.91.00.9-0.91.1-1.00.71.1
Reaction time number correct0.91.42.81.1-1.3-1.0-1.1-0.81.0-0.91.2-1.1-1.01.1-1.51.3-1.7-1.1
Reaction time mean minus median0.20.20.80.0-0.4-0.3-0.7-0.40.2-0.3-0.1-0.7-0.30.4-0.60.9-0.5-0.4
Reaction time mean minus median AUC0.10.20.6-0.80.30.40.00.4-0.60.5-0.80.00.5-0.3-0.10.30.10.3
Reaction time num false alarms0.70.91.5-1.20.81.11.11.1-1.01.0-0.91.11.0-0.90.7-0.80.71.0
Reaction time num false alarms AUC0.50.71.1-1.10.60.90.81.0-0.90.9-0.80.80.9-0.70.6-0.70.50.8
Reaction time trials correct on left0.91.42.81.1-1.3-1.0-1.1-0.81.0-0.91.2-1.1-1.01.1-1.51.3-1.7-1.1
Reaction time trials on left0.91.32.71.1-1.2-0.9-1.1-0.80.9-0.91.2-1.1-1.01.1-1.41.3-1.6-1.0
Reaction time mean0.10.10.3-0.10.50.2-0.10.1-0.30.2-0.2-0.10.2-0.40.4-0.40.60.3
Reaction time mean AUC0.00.10.2-0.00.40.1-0.1-0.0-0.20.1-0.1-0.10.1-0.30.4-0.40.50.2
Median of all reaction times0.50.71.5-0.51.00.70.60.6-0.80.8-0.50.60.8-1.01.1-1.21.20.8
Reaction time omissions0.91.21.6-0.91.11.10.91.1-0.91.1-1.10.91.0-1.11.3-1.21.11.2
Reaction time false alarm rate1.11.62.3-1.51.21.31.21.3-1.31.2-1.31.21.3-1.21.2-1.31.31.3
Reaction time premature initiation rate0.20.30.7-0.80.60.60.30.6-0.50.4-0.80.30.4-0.60.4-0.30.50.6
Reaction time premature initiations0.10.20.40.0-0.4-0.1-0.5-0.10.3-0.40.1-0.5-0.40.3-0.60.6-0.6-0.2
Std. dev. reaction times0.00.00.2-0.30.10.1-0.30.0-0.10.1-0.4-0.30.1-0.0-0.20.3-0.00.0
Reaction time trials completed0.91.32.71.1-1.2-0.9-1.1-0.80.9-0.91.2-1.1-1.01.1-1.41.3-1.6-1.0
Reaction time trials AUC0.81.12.40.9-1.1-0.8-1.0-0.70.8-0.71.1-1.0-0.81.0-1.41.3-1.5-1.0
Social response proportion0.10.10.50.0-0.2-0.1-0.1-0.1-0.00.0-0.0-0.10.10.2-0.50.7-0.2-0.2
Social responses0.10.10.4-0.20.10.40.60.4-0.30.2-0.40.60.2-0.20.3-0.40.10.3
Social time0.00.10.30.1-0.40.0-0.00.10.1-0.10.0-0.0-0.00.3-0.50.3-0.5-0.1
Conditioned locomotion0.10.20.4-0.40.40.20.40.2-0.20.4-0.60.40.5-0.40.4-0.20.50.3
Cocaine response after cond. corrected2.02.33.3-1.31.31.71.81.8-1.71.8-1.61.81.8-1.30.7-0.61.01.5
Cocaine response after cond. not corrected3.13.44.8-1.91.62.12.12.2-2.22.2-2.22.12.1-1.70.8-0.61.21.8
Cocaine response before conditioning0.60.71.9-1.30.80.90.70.8-1.10.9-1.40.70.8-0.80.3-0.10.70.7
Saline control response0.20.30.9-0.90.10.50.40.5-0.60.6-1.00.40.6-0.1-0.60.7-0.30.2
Condit. Reinf. active minus inactive responses0.70.81.4-0.90.90.90.70.9-0.80.7-1.10.70.7-0.91.1-1.20.91.0
Condit. Reinf. active-inactive response ratio0.50.51.4-0.50.60.70.60.7-0.50.5-0.50.60.5-0.71.0-1.20.60.8
Condit. Reinf. active responses1.21.62.8-1.31.21.31.11.4-1.11.0-1.51.11.0-1.31.5-1.71.21.4
Condit. Reinf. inactive responses2.02.53.7-1.91.51.61.51.7-1.61.4-1.91.51.4-1.61.5-1.61.41.6
Condit. Reinf. lever presses0.10.10.4-0.40.30.20.10.2-0.20.1-0.60.10.1-0.30.3-0.50.30.2
Condit. Reinf. lever reinforcers received1.11.62.8-1.31.21.21.11.3-1.10.9-1.51.11.0-1.31.6-1.71.21.4
Pavlov. Cond. lever latency0.30.40.70.5-0.5-0.6-0.5-0.70.6-0.60.8-0.5-0.60.6-0.60.8-0.5-0.6
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.3-0.1-0.10.00.00.0-0.1-0.10.00.2-0.50.5-0.5-0.2
Pavlov. Cond. change in total contacts0.60.81.1-0.60.90.80.90.9-0.80.8-0.90.90.9-1.01.0-1.00.90.9
Pavlov. Cond. index score0.20.30.6-0.40.40.60.50.7-0.60.6-0.80.50.6-0.50.3-0.50.30.5
Pavlov. Cond. latency score0.10.20.5-0.30.30.50.40.5-0.40.5-0.70.40.5-0.30.2-0.30.10.4
Pavlov. Cond. lever contacts0.81.11.8-1.10.91.11.01.2-1.11.1-1.41.01.1-1.00.9-1.10.81.1
Pavlov. Cond. magazine entry number0.10.10.40.2-0.2-0.4-0.4-0.40.4-0.50.6-0.4-0.50.2-0.0-0.00.0-0.3
Pavlov. Cond. intertrial magazine entries1.72.12.91.4-1.2-1.6-1.6-1.71.4-1.61.5-1.6-1.61.3-1.31.4-1.0-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.20.20.40.30.5-0.40.4-0.60.30.5-0.30.2-0.30.10.4
Pavlov. Cond. response bias1.01.41.9-1.01.11.31.21.4-1.21.2-1.41.21.3-1.21.1-1.20.91.3
Conditioned reinforcement - actives1.11.12.0-1.41.01.01.11.0-1.01.0-1.31.11.0-1.00.5-0.40.91.0
Conditioned reinforcement - inactives1.41.62.9-1.31.41.11.21.1-1.01.0-1.11.21.0-1.41.5-1.71.51.3
Conditioned locomotion0.91.01.7-1.21.01.10.91.1-1.31.2-1.10.91.2-1.00.5-0.10.81.0
Intermittent access intake day 1-15 change0.20.20.5-0.60.40.30.00.3-0.20.2-0.40.00.2-0.40.7-0.60.40.4
Intermittent access intake escalation0.10.10.5-0.40.30.20.00.2-0.10.1-0.20.00.1-0.30.7-0.60.30.3
Intermittent access intake escalation 20.10.10.20.2-0.3-0.2-0.3-0.20.3-0.30.4-0.3-0.30.20.1-0.1-0.2-0.2
Intermitt. access day 1 inactive lever presses1.11.23.9-1.01.00.90.60.9-0.60.6-0.90.60.6-1.12.0-2.01.21.2
Intermitt. access day 15 inactive lever presses3.53.96.3-1.42.11.91.61.9-2.12.0-1.51.62.0-2.12.5-2.52.22.0
Intermitt. access escalation Index1.21.01.90.8-1.0-0.9-1.2-1.00.7-0.70.5-1.2-0.71.1-1.41.3-1.2-1.1
Intermittent access day 1 total infusions0.10.10.3-0.30.30.30.50.4-0.20.3-0.40.50.3-0.40.2-0.40.30.4
Intermittent access day 15 total infusions0.30.30.6-0.60.60.50.50.5-0.30.4-0.60.50.4-0.60.8-0.80.50.6
Intermittent access terminal intake (last 3 days)0.40.41.1-0.70.70.60.60.6-0.40.4-0.60.60.4-0.70.9-1.00.70.7
Intermittent access total infusions0.10.10.3-0.20.20.10.30.20.1-0.0-0.20.3-0.0-0.20.3-0.50.20.2
Intermittent access day 1 locomotion0.30.30.5-0.60.60.50.70.5-0.50.6-0.50.70.6-0.60.5-0.40.60.5
Intermittent access day 15 total locomotion0.50.50.7-0.80.70.70.80.8-0.80.8-0.80.80.8-0.70.6-0.40.50.7
Intermittent access total locomotion0.70.70.9-0.90.90.80.80.8-0.80.9-0.80.80.9-0.90.9-0.80.90.9
Intermittent access standard deviation0.60.72.2-0.50.90.50.80.5-0.30.3-0.40.80.3-0.81.5-1.51.00.8
Cocaine induced anxiety2.12.53.21.6-1.8-1.5-1.6-1.41.6-1.61.5-1.6-1.61.7-1.51.2-1.7-1.5
Post-drug Anxiety0.10.10.30.1-0.4-0.10.1-0.10.2-0.20.10.1-0.20.3-0.50.4-0.4-0.3
Baseline Anxiety2.93.14.8-1.91.81.72.21.6-1.91.9-1.82.21.9-1.81.2-1.01.61.6
Lifetime Intake0.10.10.4-0.20.20.10.20.10.1-0.1-0.20.2-0.1-0.20.4-0.60.30.2
Incentive Sensitization - Responses1.31.32.1-0.91.21.11.01.2-1.21.2-0.91.01.2-1.21.0-1.51.21.1
Incentive Sensitization - Breakpoint1.31.32.1-0.81.21.11.01.2-1.21.2-0.81.01.2-1.21.0-1.51.21.1
Progressive ratio test 1 active lever presses1.41.42.5-1.01.21.11.61.1-1.21.1-1.11.61.1-1.10.9-1.11.31.1
Progressive ratio test 1 breakpoint1.21.22.2-1.11.11.01.51.0-1.01.0-1.11.51.0-1.00.9-1.01.21.0
Progressive ratio test 1 inactive lever presses1.31.43.6-1.01.21.01.10.9-0.90.9-1.01.10.9-1.21.6-1.91.31.2
Progressive ratio test 2 active lever presses1.41.52.2-1.01.21.11.51.1-1.11.1-1.01.51.1-1.31.1-1.51.31.1
Progressive ratio test 2 breakpoint1.11.21.8-1.01.11.01.31.0-1.11.1-1.01.31.1-1.10.9-1.31.31.0
Progressive ratio test 2 inactive lever presses0.20.21.00.10.40.30.50.4-0.30.30.00.50.3-0.50.7-1.00.50.4
Total sessions with >9 infusions0.80.91.2-1.01.00.91.10.8-0.90.8-1.01.10.8-1.01.1-1.01.00.9
Short access day 1 total inactive lever presses1.61.73.3-1.31.41.21.11.3-1.11.1-1.21.11.1-1.41.8-1.61.41.5
Short access day 10 total inactive lever presses0.60.61.50.8-0.7-0.7-1.2-0.70.8-0.90.8-1.2-0.90.7-0.10.2-0.6-0.6
Short access day 1 total infusions0.40.41.7-0.60.60.40.40.4-0.20.2-0.40.40.2-0.61.2-1.30.90.6
Short access day 10 total infusions0.30.30.7-0.40.50.50.80.6-0.40.4-0.40.80.4-0.50.6-0.60.40.5
Short access total infusions0.10.10.6-0.10.30.00.20.10.2-0.1-0.10.2-0.1-0.20.6-0.80.40.2
Short access day 1 locomotion3.13.36.0-1.51.91.71.61.7-1.51.6-1.51.61.6-1.92.5-2.42.11.9
Short access day 10 total locomotion1.92.02.7-1.61.41.41.41.4-1.51.5-1.51.41.5-1.41.2-1.41.41.4
Short access total locomotion0.50.50.9-0.90.70.50.60.5-0.40.5-0.80.60.5-0.70.9-1.00.80.7
Compulsive drug intake0.10.10.30.1-0.2-0.4-0.5-0.50.3-0.4-0.0-0.5-0.40.3-0.50.5-0.1-0.4
One hour access (0.3 mA shock)0.00.00.1-0.30.1-0.0-0.0-0.00.1-0.0-0.3-0.0-0.0-0.1-0.10.20.10.0
One hour access (shock baseline)0.10.20.4-0.60.30.40.50.4-0.20.3-0.40.50.3-0.40.5-0.40.30.4
Number of responses in last shaping day0.10.10.70.30.30.00.10.00.2-0.00.20.1-0.0-0.30.8-0.80.50.3
Context. condit. distance diff. score0.60.81.60.6-0.7-0.9-1.0-1.00.7-0.70.5-1.0-0.70.8-1.21.3-0.7-1.0
Locomotion velocity, session 10.70.71.11.1-0.9-0.8-0.7-0.80.9-0.91.1-0.7-0.90.9-0.60.8-0.9-0.8
Locomotion distance, session 13.64.76.32.3-2.4-2.1-1.9-2.02.4-2.42.3-1.9-2.42.3-1.71.9-2.5-2.0
Locomotion velocity, session 20.50.61.31.0-0.7-0.8-0.7-0.80.9-0.91.1-0.7-0.90.7-0.30.4-0.5-0.7
Locomotion distance, session 20.71.11.91.4-1.1-0.9-0.7-0.81.2-1.21.3-0.7-1.21.1-0.40.6-1.3-0.8
Locomotion velocity, session 30.10.10.30.3-0.2-0.4-0.4-0.50.5-0.50.2-0.4-0.50.20.3-0.10.0-0.2
Locomotion distance, session 30.40.50.80.9-0.7-0.7-0.6-0.70.8-0.80.6-0.6-0.80.7-0.40.6-0.7-0.7
Stereotopy head waving bouts, day 33.64.35.2-2.22.22.02.01.9-2.12.1-2.22.02.1-2.12.0-1.92.32.0
Stereotopy head waving duration, day 30.40.50.9-1.00.70.70.60.7-0.70.7-0.90.60.7-0.70.5-0.60.80.6
Locomotion velocity, session 71.01.12.20.7-1.2-1.0-0.9-0.91.0-1.00.6-0.9-1.01.2-1.21.5-1.4-1.1
Locomotion distance, session 70.20.31.10.2-0.6-0.5-0.3-0.40.5-0.50.1-0.3-0.50.6-0.91.1-0.8-0.5
Stereotopy head waving bouts, day 70.91.11.4-0.91.01.11.01.0-1.21.2-1.21.01.2-1.00.9-0.81.01.0
Stereotopy head waving duration, day 70.30.30.4-0.40.60.60.50.6-0.70.7-0.60.50.7-0.60.7-0.60.60.6
Locomotion velocity, session 87.69.19.82.8-3.1-3.0-3.0-3.03.0-3.02.7-3.0-3.03.1-3.13.1-3.1-3.1
Locomotion distance, session 81.62.43.01.7-1.6-1.5-1.4-1.51.6-1.61.4-1.4-1.61.6-1.51.5-1.7-1.5
Degree of sensitization distance0.60.61.40.3-0.7-0.7-0.7-0.60.6-0.60.5-0.7-0.60.7-1.21.2-0.8-0.8
Degree of sensitization stereotypy1.51.72.2-1.21.21.41.31.4-1.51.5-1.41.31.5-1.20.9-0.81.11.3
Condit. Reinf. active minus inactive responses0.60.61.2-0.71.00.70.80.6-0.70.7-0.60.80.7-0.91.1-0.81.00.8
Condit. Reinf. active-inactive response ratio0.80.91.6-1.11.10.70.80.6-0.80.8-0.90.80.8-1.11.2-0.91.30.9
Condit. Reinf. active responses0.80.91.4-0.91.10.91.00.9-1.01.0-0.71.01.0-1.11.1-0.81.21.0
Condit. Reinf. inactive responses0.40.50.8-0.70.60.80.60.9-0.90.9-0.50.60.9-0.70.3-0.10.50.7
Incentive salience index mean1.62.02.8-1.31.51.31.41.3-1.31.3-1.11.41.3-1.51.7-1.41.61.5
Condit. Reinf. lever presses1.11.51.8-1.11.21.31.31.3-1.21.2-1.01.31.2-1.21.2-1.01.11.3
Time in familiar zone, hab. session 10.50.50.9-0.90.40.80.61.0-0.60.6-0.90.60.6-0.50.5-0.70.20.7
Time in novel zone, hab. session 10.80.81.5-0.81.10.70.90.5-0.90.9-0.80.90.9-1.01.0-0.61.20.8
Total zone transitions, hab. session 12.13.03.81.9-1.7-1.7-1.7-1.71.8-1.81.8-1.7-1.81.7-1.41.5-1.7-1.7
Total locomotion distance, hab. session 10.00.00.10.2-0.1-0.2-0.3-0.20.2-0.20.1-0.3-0.20.10.10.1-0.1-0.1
Locomotion velocity, hab. session 10.50.81.00.9-0.8-0.9-1.0-0.91.0-1.00.8-1.0-1.00.8-0.60.6-0.8-0.9
Time in familiar zone, hab. session 20.50.50.8-0.80.60.70.70.8-0.60.6-0.90.70.6-0.60.7-0.90.50.8
Time in novel zone, hab. session 20.10.10.3-0.20.40.20.20.1-0.30.3-0.10.20.3-0.40.5-0.40.60.3
Total zone transitions, hab. session 20.81.01.80.9-1.1-0.9-0.8-0.90.9-0.91.0-0.8-0.91.1-1.11.3-1.3-1.0
Total locomotion distance, hab. session 20.20.20.70.2-0.6-0.3-0.4-0.30.4-0.40.3-0.4-0.40.6-0.50.7-0.8-0.4
Locomotion velocity, hab. session 20.40.51.20.4-0.9-0.6-0.7-0.50.7-0.70.6-0.7-0.70.8-0.81.0-1.1-0.7
Novel to familiar place preference ratio1.31.31.81.3-1.0-1.3-1.2-1.31.1-1.11.2-1.2-1.11.1-1.11.1-0.9-1.3
Novelty place preference0.80.91.30.9-0.8-1.1-1.0-1.20.9-0.90.9-1.0-0.90.8-1.01.0-0.6-1.1
Time in novel zone, NPP test0.20.20.40.5-0.3-0.6-0.5-0.70.4-0.40.4-0.5-0.40.4-0.60.5-0.2-0.6
Total zone transitions, NPP test0.40.61.40.7-1.0-0.6-0.5-0.50.7-0.70.7-0.5-0.70.9-0.90.9-1.2-0.7
Total locomotion distance, NPP test0.00.00.10.0-0.10.20.20.2-0.00.0-0.10.20.00.1-0.00.1-0.40.1
Locomotion velocity, NPP test0.30.40.90.7-0.8-0.5-0.5-0.40.6-0.60.5-0.5-0.60.7-0.60.7-1.0-0.6
Pavlov. Cond. lever latency3.03.84.71.9-1.8-2.1-2.0-2.22.0-2.01.9-2.0-2.01.9-1.91.9-1.6-2.1
Pavlov. Cond. magazine entry latency10.814.015.1-3.73.83.83.63.8-3.73.7-3.73.63.7-3.83.7-3.73.63.9
Pavlov. Cond. change in total contacts9.510.111.9-2.93.43.13.03.0-3.13.1-3.03.03.1-3.33.5-3.43.43.3
Pavlov. Cond. index score9.011.512.8-3.33.33.53.33.6-3.43.4-3.43.33.4-3.43.3-3.33.13.5
Pavlov. Cond. latency score7.08.910.2-2.92.93.23.03.2-3.13.1-3.03.03.1-3.02.8-2.92.73.1
Pavlov. Cond. lever contacts2.63.14.0-1.81.61.91.72.0-1.81.8-1.81.71.8-1.71.6-1.71.41.9
Pavlov. Cond. magazine entry number13.817.318.73.9-4.2-4.3-4.0-4.24.2-4.24.1-4.0-4.24.3-4.24.1-4.1-4.3
Pavlov. Cond. intertrial magazine entries1.61.92.71.4-1.3-1.5-1.3-1.51.3-1.31.6-1.3-1.31.3-1.31.5-1.2-1.5
Pavlov. Cond. lever-magazine prob. diff.10.212.813.8-3.53.53.73.53.7-3.63.6-3.63.53.6-3.63.5-3.43.43.7
Pavlov. Cond. response bias10.212.513.5-3.43.63.63.43.6-3.53.5-3.63.43.5-3.63.5-3.53.53.7
Bone: apparent density2.44.04.6-1.72.12.11.92.0-2.12.1-1.61.92.1-2.02.1-2.02.12.1
Bone surface0.00.00.10.2-0.10.10.20.10.00.00.20.2-0.00.10.2-0.2-0.10.1
Bone volume0.10.20.4-0.20.30.60.60.6-0.40.5-0.10.60.5-0.30.5-0.60.20.5
Bone: connectivity density3.25.06.0-2.02.32.22.22.1-2.22.2-2.02.22.2-2.32.5-2.22.42.3
Bone: cortical apparent density6.48.310.7-2.63.22.82.72.8-2.82.8-2.82.72.8-3.23.1-2.73.33.0
Bone: cortical area0.20.20.5-0.50.50.60.40.6-0.70.7-0.40.40.7-0.50.2-0.10.30.5
Bone: cortical porosity0.40.50.8-0.90.50.80.40.9-0.80.9-0.90.40.9-0.60.3-0.40.50.7
Bone: cortical porosity0.50.51.0-1.00.50.90.41.0-1.01.0-0.90.41.0-0.60.0-0.10.30.7
Bone: cortical thickness1.52.43.7-1.41.71.71.21.6-1.91.9-1.51.21.9-1.71.3-0.81.61.6
Bone: cortical thickness5.36.27.7-2.52.72.52.12.4-2.62.4-2.52.12.4-2.72.6-2.32.82.6
Bone: cortical tissue density6.48.310.8-2.63.22.82.72.8-2.82.8-2.82.72.8-3.23.1-2.73.33.0
Bone: elastic displacement0.00.00.10.00.10.1-0.10.1-0.20.1-0.1-0.10.1-0.10.00.20.10.1
Bone: elastic work0.00.00.00.20.00.10.00.2-0.10.00.00.00.0-0.10.2-0.1-0.10.2
Bone: endosteal estimation2.14.66.31.9-2.5-2.2-1.6-2.02.3-2.42.0-1.6-2.42.4-2.21.6-2.5-2.2
Bone: endosteal perimeter1.73.54.51.8-2.1-2.0-1.5-1.82.1-2.12.0-1.5-2.12.0-1.71.2-1.9-1.9
Bone: final force1.01.62.4-1.51.11.51.31.5-1.41.4-1.51.31.4-1.10.8-0.90.91.3
Bone: final moment0.81.31.9-1.30.91.31.11.4-1.31.3-1.31.11.3-1.00.6-0.70.71.1
Bone: marrow area2.04.35.91.9-2.4-2.1-1.6-2.02.2-2.31.9-1.6-2.32.4-2.11.5-2.4-2.2
Bone: maximum diameter0.00.00.1-0.20.10.20.30.2-0.20.1-0.00.30.1-0.10.1-0.30.10.2
Bone: maximum force0.00.10.1-0.3-0.00.30.20.4-0.30.3-0.40.20.3-0.0-0.20.0-0.20.2
Bone: maximum moment0.00.00.1-0.2-0.20.20.10.2-0.20.2-0.30.10.20.1-0.30.1-0.30.0
Bone: minimum diameter0.40.81.50.7-1.1-0.9-0.4-0.81.0-1.00.8-0.4-1.01.0-1.00.8-1.2-1.0
Bone: periosteal estimation0.20.40.80.5-0.8-0.6-0.3-0.50.6-0.70.5-0.3-0.70.8-0.80.4-0.9-0.7
Bone: periosteal perimeter0.71.11.70.9-1.3-1.0-1.0-0.91.0-1.11.1-1.0-1.11.2-1.10.8-1.3-1.1
Bone: post-yield work1.21.62.00.9-1.4-1.2-1.3-1.31.2-1.21.0-1.3-1.21.4-1.41.3-1.4-1.3
Bone: stiffness0.00.10.2-0.40.10.30.40.3-0.20.3-0.40.40.3-0.1-0.1-0.1-0.00.2
Bone: tissue strength0.60.51.10.7-0.8-0.6-0.9-0.70.5-0.40.4-0.9-0.40.8-1.01.0-0.8-0.8
Bone: trabecular number5.58.59.3-2.72.93.02.93.0-2.93.0-2.62.93.0-2.93.0-2.92.93.0
Bone: trabecular spacing1.21.62.81.0-1.5-1.1-1.1-1.01.1-1.10.9-1.1-1.11.4-1.61.4-1.7-1.3
Bone: trabecular thickness0.10.10.30.00.30.3-0.10.3-0.30.30.0-0.10.3-0.30.5-0.50.30.4
Bone: trabecular tissue density0.00.00.4-0.10.4-0.1-0.0-0.2-0.10.1-0.1-0.00.1-0.30.10.20.6-0.0
Breakpoint value in progressive ratio session0.91.01.71.0-0.9-1.0-0.8-0.91.2-1.31.2-0.8-1.30.8-0.50.9-0.9-0.8
Distance traveled before self-admin0.20.20.30.3-0.5-0.5-0.4-0.30.5-0.60.5-0.4-0.50.4-0.3-0.4-0.4-0.4
Distance traveled after self-admin1.61.83.01.0-1.5-1.5-1.1-1.41.7-1.71.3-1.1-1.61.5-1.00.6-1.2-1.4
Delta time in closed arm before/after self-admin4.44.36.71.6-2.1-1.9-2.6-1.91.9-1.91.7-2.6-1.92.1-1.82.3-2.3-2.0
Delta time in open arm before/after self-admin0.10.10.20.00.20.20.10.3-0.40.50.10.10.1-0.2-0.1-0.50.10.2
Diff in mean of infusions in LGA sessions0.60.61.40.1-0.7-0.7-1.2-0.60.8-0.90.3-1.2-0.90.6-0.71.1-0.8-0.6
Extinction: sum of active levers before priming1.21.22.30.7-1.2-1.0-0.8-1.00.9-0.90.8-0.8-1.01.2-1.41.5-1.3-1.2
Active lever presses in extinction session 60.60.61.6-0.50.40.81.31.0-0.50.5-0.51.30.5-0.60.8-0.80.40.8
Delta distance traveled before/after self-admin1.21.31.70.9-1.1-1.2-0.9-1.31.3-1.31.0-0.9-1.11.2-1.01.3-1.1-1.2
Delta ambulatory time before/after self-admin0.50.51.00.2-0.8-0.7-0.6-0.80.8-0.70.3-0.6-0.60.9-0.71.0-0.7-0.8
Time in closed arm before self-admin1.71.93.9-1.11.41.11.61.0-1.00.9-1.21.61.1-1.31.7-2.01.91.3
Time in closed arm after self-admin0.50.51.10.7-0.6-0.9-0.7-1.00.9-1.00.5-0.7-0.70.6-0.20.3-0.4-0.8
Time in open arm before self-admin3.43.65.21.8-1.9-1.9-1.6-1.72.0-2.01.8-1.6-1.71.9-2.02.3-2.3-1.9
Time in open arm after self-admin0.70.81.40.7-0.9-0.8-1.0-0.70.8-0.61.1-1.0-1.00.8-1.20.7-1.0-0.9
Sum of active levers in priming session hrs 5-60.40.40.6-0.50.50.60.70.7-0.60.5-0.60.70.6-0.60.6-0.00.70.6
Time to tail flick, vehicle, before self-admin0.20.20.3-0.40.30.50.30.5-0.50.5-0.60.30.4-0.30.2-0.50.20.4
Time to tail flick, vehicle, after self-admin0.10.10.3-0.30.30.40.10.4-0.50.3-0.50.10.5-0.30.20.00.20.3
Time to tail flick, test, before self-admin1.21.22.20.7-1.2-1.0-1.1-1.01.0-1.10.6-1.1-0.91.2-1.51.2-1.3-1.1
Time to tail flick, test, after self-admin0.20.20.40.20.20.50.30.6-0.30.3-0.10.30.5-0.30.5-0.60.10.5
Delta time to tail flick, vehicle, before/after SA0.30.30.5-0.50.40.60.50.7-0.60.5-0.60.50.6-0.40.3-0.10.40.6
Delta time to tail flick, test, before/after SA2.72.43.2-0.91.61.61.61.7-1.61.7-1.01.61.6-1.71.8-1.51.51.7
Ambulatory time before self-admin0.40.41.00.8-0.7-0.7-0.4-0.60.7-0.81.0-0.4-0.80.6-0.4-0.0-0.5-0.6
Ambulatory time after self-admin2.83.14.61.6-2.0-1.8-1.6-1.82.1-2.21.8-1.6-2.02.0-1.10.7-1.6-1.8
Total heroin consumption0.70.81.8-0.30.81.01.01.1-0.70.7-0.21.00.6-0.91.1-1.30.71.0
Area under the delay curve0.60.61.1-0.70.80.80.80.8-0.91.0-0.80.81.0-0.80.6-0.40.60.8
Delay disc. indifference point, 0s delay1.21.31.6-0.91.21.21.21.2-1.31.1-1.01.21.1-1.21.1-0.91.11.2
Delay disc. indifference point, 16s delay0.70.71.2-0.81.00.80.80.6-0.90.9-0.80.80.9-0.90.7-0.71.10.8
Delay disc. indifference point, 2s delay2.02.23.0-1.41.31.71.71.7-1.71.7-1.61.71.7-1.41.0-0.80.91.5
Delay disc. indifference point, 24s delay0.10.10.2-0.30.30.20.10.1-0.30.4-0.30.10.4-0.2-0.0-0.10.40.1
Delay disc. indifference point, 4s delay0.60.71.1-0.30.80.91.01.0-1.01.1-0.31.01.1-0.90.7-0.60.50.9
Delay disc. indifference point, 8s delay0.40.40.7-0.60.60.60.70.5-0.70.9-0.60.70.9-0.50.4-0.30.50.5
Delay discount exponential model param0.30.30.70.5-0.5-0.6-0.6-0.60.6-0.80.5-0.6-0.80.5-0.40.3-0.4-0.5
Delay discount hyperbolic model param0.50.50.90.6-0.7-0.8-0.8-0.70.8-1.00.7-0.8-1.00.7-0.60.4-0.5-0.7
Fecal boli incidents, locomotor time 10.20.20.40.6-0.5-0.4-0.4-0.30.4-0.30.6-0.4-0.30.5-0.40.5-0.6-0.5
Change in fecal boli incidents, locomotor task0.10.10.3-0.50.10.20.30.2-0.30.3-0.50.30.3-0.1-0.30.40.10.1
Time >=10cm from walls, locomotor time 10.60.60.9-0.70.90.81.00.7-0.80.9-0.81.00.9-0.80.40.00.80.7
Bouts of movement, locomotor time 10.70.71.01.0-0.9-0.9-0.8-0.90.9-1.01.0-0.8-1.00.9-0.50.5-0.6-0.9
Total resting periods, locomotor time 11.01.21.51.0-1.2-1.1-1.1-1.11.1-1.11.1-1.1-1.11.2-0.90.9-1.0-1.1
Rest time, locomotor task time 10.00.00.30.2-0.00.0-0.1-0.00.1-0.00.3-0.1-0.00.00.5-0.50.20.0
Distance moved, locomotor task time 10.30.30.6-0.80.40.50.70.6-0.50.5-0.80.70.5-0.50.00.10.20.5
Vertical activity count, locomotor time 10.20.21.3-0.0-0.4-0.20.2-0.00.1-0.10.00.2-0.10.3-0.91.1-0.8-0.3
Time >=10cm from walls, locomotor time 21.71.83.3-1.21.41.41.81.5-1.61.6-1.21.81.6-1.40.4-0.20.91.3
Bouts of movement, locomotor time 20.10.10.4-0.00.40.00.1-0.1-0.20.00.00.10.0-0.30.5-0.60.60.2
Total resting periods, locomotor time 20.10.10.20.20.2-0.2-0.2-0.30.1-0.20.3-0.2-0.2-0.10.4-0.40.4-0.1
Rest time, locomotor task time 21.31.52.51.4-1.2-1.2-1.1-1.21.2-1.31.6-1.1-1.31.2-1.01.0-1.2-1.2
Distance moved, locomotor task time 20.10.10.3-0.2-0.00.20.60.3-0.10.2-0.30.60.2-0.1-0.20.4-0.40.2
Vertical activity count, locomotor time 20.10.21.0-0.1-0.4-0.1-0.0-0.10.1-0.1-0.2-0.0-0.10.3-0.61.0-0.7-0.2
Weight adjusted by age0.30.41.10.5-0.6-0.4-0.6-0.30.3-0.40.5-0.6-0.40.5-0.91.1-0.9-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.00.40.00.20.0-0.0-0.10.10.2-0.1-0.40.40.00.70.2
Locomotion in novel chamber5.97.39.3-2.12.72.83.02.9-3.12.9-2.13.02.9-2.92.4-2.12.52.8
Locomotion in novel chamber post-restriction0.91.11.8-0.90.81.21.41.3-1.01.0-1.11.41.0-0.90.8-1.00.71.2
Progressive ratio0.00.00.2-0.10.00.10.40.20.00.0-0.10.40.0-0.10.20.10.00.2
Food seeking constrained by brief footshock0.30.30.8-0.40.50.60.80.6-0.30.4-0.40.80.4-0.50.6-0.90.70.6
Seeking ratio, punishment vs. effort0.10.10.3-0.30.40.40.20.3-0.50.5-0.30.20.5-0.30.1-0.50.50.3
Run reversals in cocaine runway, females2.72.73.51.4-1.6-1.7-1.7-1.71.5-1.61.4-1.7-1.61.6-1.81.9-1.5-1.7
Run reversals in cocaine runway, males0.60.61.0-0.70.70.80.70.8-0.91.0-0.60.71.0-0.80.5-0.90.70.7
Latency to leave start box in cocaine runway2.62.84.12.0-1.7-1.7-1.7-1.61.8-1.62.0-1.7-1.61.6-1.41.2-1.6-1.6
Latency to leave start box in cocaine runway, F2.42.73.61.9-1.7-1.6-1.8-1.41.6-1.51.8-1.8-1.51.6-1.61.3-1.8-1.6
Latency to leave start box in cocaine runway, M0.20.20.70.7-0.0-0.30.2-0.30.4-0.30.80.2-0.30.00.8-0.70.3-0.1
Cd content in liver0.10.20.3-0.50.30.30.50.3-0.20.2-0.40.50.2-0.30.5-0.60.30.4
Co content in liver1.11.31.81.3-1.0-1.2-1.1-1.21.3-1.31.2-1.1-1.31.0-0.70.7-0.8-1.1
Cu content in liver0.50.61.41.1-0.5-0.9-0.2-0.91.2-1.01.2-0.2-1.00.60.1-0.0-0.3-0.6
Fe content in liver1.41.62.41.4-1.4-1.2-1.1-1.21.3-1.31.3-1.1-1.31.4-1.21.1-1.5-1.3
K content in liver0.80.81.8-0.30.90.81.40.8-0.70.7-0.21.40.7-0.91.0-1.10.90.9
Mg content in liver0.70.71.4-0.31.10.61.00.5-0.70.8-0.31.00.8-1.01.0-1.11.20.8
Mn content in liver1.31.53.0-0.71.41.01.70.9-0.80.8-0.51.70.8-1.31.7-1.71.51.2
Na content in liver0.20.20.5-0.30.30.60.60.7-0.50.5-0.20.60.5-0.40.3-0.40.20.5
Rb content in liver1.51.93.2-1.21.31.21.81.2-1.11.2-1.11.81.2-1.31.5-1.51.41.3
Se content in liver3.84.68.1-1.52.31.92.21.9-1.81.8-1.42.21.8-2.32.8-2.92.52.2
Sr content in liver0.10.10.20.4-0.0-0.3-0.0-0.30.4-0.40.4-0.0-0.40.00.3-0.20.1-0.2
Zn content in liver2.42.65.0-1.41.71.51.61.5-1.31.3-1.31.61.3-1.72.1-2.21.71.7