Hub : Genes

Myrf

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000028274 0.04 0.02 2.0e-03 0.02 0.01 0 0.01 2.9e-03 6.0e-02 2.7e-01 2.5e-02
2 Brain gene expression ENSRNOG00000028274 0.12 0.08 7.4e-08 0.08 0.08 0.08 0.09 4.4e-08 5.6e-08 1.4e-07 1.6e-08
3 Liver isoform ratio ENSRNOT00000094966 0.14 0.07 1.0e-12 0.09 0.08 0.07 0.09 4.5e-10 2.0e-09 1.1e-08 7.7e-10
4 Liver isoform ratio ENSRNOT00000116485 0.05 0.03 3.4e-05 0.03 0.03 0.01 0.02 3.0e-04 7.1e-04 7.9e-03 1.8e-03
5 Liver intron excision ratio chr1:206860518:206860689 0.1 0.07 3.8e-05 0.04 0.03 0.03 0.03 4.5e-05 2.3e-04 2.5e-04 1.1e-04
6 Liver intron excision ratio chr1:206860518:206861185 0.13 0.06 5.8e-15 0.09 0.08 0.11 0.08 5.9e-10 3.5e-09 5.9e-12 6.9e-09
7 Liver intron excision ratio chr1:206860521:206860689 0.11 0.06 1.5e-10 0.06 0.06 0.05 0.06 1.7e-07 1.7e-07 1.2e-06 1.0e-07
8 Liver intron excision ratio chr1:206860521:206861185 0.11 0.07 1.1e-06 0.05 0.04 0.03 0.05 1.9e-06 7.0e-05 1.8e-04 7.6e-06
9 Liver intron excision ratio chr1:206860769:206861185 0.11 0.06 2.3e-09 0.06 0.06 0.06 0.07 1.1e-07 1.5e-07 4.8e-07 7.0e-08
10 NAcc gene expression ENSRNOG00000028274 0.04 0.03 2.2e-03 0.01 0.02 0.01 0.01 1.0e-01 7.7e-03 4.3e-02 3.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.20.81.50.4-0.1-1.20.61.2-0.30.7-1.21.2-0.6
BMI without tail0.10.21.1-0.5-0.70.1-0.3-0.10.2-0.40.1-0.1-1.0
Body weight0.31.24.5-0.1-2.10.80.1-0.80.6-0.40.8-0.8-2.1
Epididymis fat weight1.94.46.12.31.7-2.02.42.0-2.12.5-2.02.02.0
Glucose3.14.76.51.62.5-2.31.82.3-1.71.9-2.32.32.6
Heart weight0.81.21.40.91.1-1.11.21.1-1.11.0-1.11.11.2
Left kidney weight0.51.43.71.90.4-0.71.90.7-1.31.5-0.80.80.9
Right kidney weight0.30.71.91.40.3-0.61.30.6-0.91.1-0.60.60.5
Tail length1.23.75.5-1.3-2.32.2-1.1-2.21.4-1.72.2-2.2-2.1
Length with tail0.62.15.3-0.1-2.31.60.0-1.60.8-0.71.6-1.6-2.0
Length without tail0.10.30.90.4-1.00.40.5-0.40.30.20.4-0.4-0.8
Liver weight, left0.10.20.50.20.4-0.30.20.3-0.60.4-0.30.30.7
Liver weight, right0.20.40.8-0.20.7-0.9-0.30.9-0.30.3-0.80.80.5
Parametrial fat weight4.28.311.83.42.6-2.63.32.6-2.83.3-2.52.52.9
Retroperitoneal fat weight3.912.816.84.03.2-3.24.13.2-3.74.0-3.13.13.9
Intraocular pressure0.30.40.7-0.7-0.40.6-0.6-0.60.8-0.60.6-0.6-0.4
Extensor digitorum longus weight1.35.313.2-1.3-3.32.1-1.2-2.12.4-1.82.0-2.0-3.6
Soleus weight1.13.26.11.12.4-1.71.21.7-1.91.4-1.71.72.5
Tibialis anterior weight4.816.727.7-3.2-5.13.9-3.1-3.94.5-3.73.9-3.9-5.3
Tibia length0.20.51.10.2-1.00.70.2-0.70.9-0.20.6-0.6-0.9
Number of licking bursts0.10.10.50.70.0-0.10.50.1-0.20.4-0.10.10.2
Food consumed during 24 hour testing period0.00.00.20.00.4-0.2-0.10.2-0.1-0.0-0.20.20.3
Times rat made contact with spout0.81.01.4-1.2-0.80.9-1.0-0.91.1-1.10.9-0.9-1.0
Mean time between licks in bursts0.71.01.7-1.3-1.00.7-1.2-0.71.2-1.20.7-0.7-1.3
Mean num. licks in bursts0.70.82.5-1.6-0.40.6-1.2-0.60.9-1.10.6-0.6-0.7
Std. dev. time between licks in bursts0.10.20.50.10.4-0.5-0.10.5-0.70.3-0.50.50.4
Water consumed over 24 hours0.30.30.50.1-0.70.70.1-0.70.0-0.30.7-0.7-0.7
Indifference point 0 sec0.30.40.9-0.2-0.90.7-0.0-0.70.7-0.50.7-0.7-0.7
Indifference point AUC1.21.42.6-0.8-1.31.2-1.1-1.21.6-0.91.1-1.1-1.3
Indifference point function ln k3.75.26.61.82.5-2.61.82.6-2.32.1-2.42.42.3
Indifference point function log k3.75.26.61.82.5-2.61.82.6-2.32.1-2.42.42.3
Delay discounting total patch changes 0 sec0.40.71.2-0.3-1.10.9-0.2-0.90.8-0.70.9-0.9-0.9
Delay discounting total patch changes 12 sec5.06.610.0-1.7-3.22.8-1.5-2.82.6-2.32.7-2.7-3.0
Delay discounting total patch changes 18 sec1.01.32.4-1.1-1.11.2-1.0-1.21.6-1.11.0-1.0-1.0
Delay discounting total patch changes 24 sec2.22.75.7-0.6-2.41.8-0.6-1.81.7-1.11.7-1.7-2.2
Delay discounting total patch changes 6 sec0.30.40.90.4-1.00.80.2-0.80.5-0.20.6-0.6-0.7
Delay discounting time to switch 0 sec0.10.20.40.50.3-0.50.60.5-0.40.6-0.60.60.1
Delay discounting water rate 0 sec0.00.00.20.10.30.00.1-0.0-0.2-0.00.1-0.10.4
Delay discounting water rate 12 sec0.60.91.30.51.2-1.00.81.0-1.10.7-0.90.91.1
Delay discounting water rate 18 sec0.71.02.20.80.9-1.00.91.0-1.50.9-0.90.90.9
Delay discounting water rate 24 sec0.50.61.70.50.9-0.80.80.8-1.30.6-0.60.60.9
Delay discounting water rate 6 sec0.20.30.80.30.6-0.50.80.5-0.90.4-0.40.40.7
Locomotor activity0.10.10.7-0.80.10.1-0.3-0.1-0.1-0.40.1-0.10.3
Locomotor testing distance0.10.20.8-0.90.5-0.3-0.30.3-0.3-0.3-0.40.40.5
Locomotor testing rearing0.20.30.9-0.90.8-0.5-0.60.5-0.0-0.2-0.60.60.6
Light reinforcement 10.10.20.8-0.40.50.1-0.9-0.10.4-0.2-0.10.10.3
Light reinforcement 21.31.73.01.71.3-1.11.01.1-1.01.7-1.21.21.5
Reaction time number correct0.50.71.4-0.9-0.70.6-1.2-0.60.9-0.90.6-0.6-0.9
Reaction time mean minus median1.01.31.8-1.1-1.01.1-1.3-1.11.3-1.11.0-1.0-1.0
Reaction time mean minus median AUC2.02.53.8-1.8-1.31.5-1.9-1.51.9-1.71.5-1.5-1.2
Reaction time num false alarms0.20.20.4-0.3-0.40.70.0-0.7-0.1-0.50.6-0.6-0.3
Reaction time num false alarms AUC0.91.22.0-0.7-1.21.4-0.3-1.40.5-1.11.3-1.3-0.9
Reaction time trials correct on left0.50.71.4-0.9-0.70.6-1.2-0.60.9-0.90.6-0.6-0.9
Reaction time trials on left0.60.81.7-1.0-0.80.7-1.3-0.71.0-1.00.7-0.7-1.0
Reaction time mean0.40.52.1-1.2-0.10.2-1.4-0.20.8-0.70.2-0.2-0.4
Reaction time mean AUC0.20.31.6-1.00.2-0.1-1.30.10.6-0.4-0.10.1-0.1
Median of all reaction times0.10.21.0-0.80.0-0.1-1.00.10.4-0.3-0.10.1-0.2
Reaction time omissions1.01.31.7-0.9-1.11.3-1.0-1.31.2-1.11.3-1.3-0.9
Reaction time false alarm rate0.10.20.40.1-0.40.60.6-0.6-0.4-0.10.5-0.5-0.1
Reaction time premature initiation rate0.30.41.10.8-1.00.40.9-0.4-0.20.40.3-0.3-0.9
Reaction time premature initiations0.91.33.1-0.1-1.81.2-0.3-1.20.7-0.61.1-1.1-1.7
Std. dev. reaction times1.01.32.6-1.4-0.81.1-1.6-1.11.3-1.21.1-1.1-0.7
Reaction time trials completed0.60.81.7-1.0-0.80.7-1.3-0.71.0-1.00.7-0.7-1.0
Reaction time trials AUC0.40.61.4-0.9-0.60.5-1.2-0.50.9-0.90.5-0.5-0.8
Social response proportion0.10.20.50.70.1-0.10.70.1-0.50.5-0.10.10.2
Social responses0.40.50.9-0.4-0.71.0-0.2-1.00.3-0.60.9-0.9-0.5
Social time1.21.62.9-1.7-0.91.2-1.5-1.21.1-1.51.2-1.2-1.0
Conditioned locomotion0.30.40.7-0.5-0.80.5-0.3-0.50.6-0.50.6-0.6-0.8
Cocaine response after cond. corrected0.30.30.6-0.40.7-0.8-0.50.8-0.2-0.1-0.70.70.3
Cocaine response after cond. not corrected0.50.51.0-0.41.0-0.9-0.50.9-0.00.0-0.90.90.5
Cocaine response before conditioning0.10.10.8-0.20.10.2-0.3-0.20.90.00.0-0.00.0
Saline control response1.72.33.6-1.3-1.71.4-1.4-1.41.9-1.41.3-1.3-1.8
Condit. Reinf. active minus inactive responses0.20.20.5-0.40.7-0.3-0.60.30.6-0.2-0.40.40.3
Condit. Reinf. active-inactive response ratio0.60.71.20.71.1-0.90.60.9-0.40.7-1.01.00.8
Condit. Reinf. active responses0.10.20.7-0.40.3-0.1-0.60.10.8-0.3-0.20.20.0
Condit. Reinf. inactive responses0.10.20.5-0.6-0.00.2-0.7-0.20.7-0.40.1-0.1-0.2
Condit. Reinf. lever presses0.00.10.30.0-0.1-0.1-0.20.10.60.1-0.10.1-0.3
Condit. Reinf. lever reinforcers received0.20.31.3-0.70.00.2-0.9-0.21.1-0.60.1-0.1-0.4
Pavlov. Cond. lever latency0.20.20.5-0.3-0.40.6-0.0-0.6-0.1-0.50.7-0.7-0.0
Pavlov. Cond. magazine entry latency1.82.04.1-1.3-1.41.1-1.6-1.11.9-1.31.0-1.0-2.0
Pavlov. Cond. change in total contacts0.20.31.0-0.6-0.10.0-1.0-0.01.0-0.2-0.00.0-0.7
Pavlov. Cond. index score0.30.41.4-0.4-0.50.3-0.8-0.31.2-0.30.2-0.2-1.1
Pavlov. Cond. latency score0.20.21.0-0.2-0.30.1-0.6-0.11.0-0.2-0.00.0-0.9
Pavlov. Cond. lever contacts0.20.31.1-0.80.0-0.0-1.00.01.0-0.4-0.10.1-0.6
Pavlov. Cond. magazine entry number2.22.76.21.41.8-1.41.71.4-2.11.4-1.31.32.5
Pavlov. Cond. intertrial magazine entries0.30.31.30.30.9-0.40.40.4-0.40.4-0.50.51.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.9-0.6-0.60.4-1.1-0.41.4-0.50.3-0.3-1.3
Pavlov. Cond. response bias0.40.61.6-0.9-0.50.3-1.1-0.31.3-0.60.2-0.2-1.1
Conditioned reinforcement - actives0.60.61.60.11.3-0.9-0.30.9-0.40.4-0.90.90.9
Conditioned reinforcement - inactives1.51.62.11.11.4-1.40.71.4-1.01.3-1.51.51.3
Conditioned locomotion2.63.14.01.62.0-1.81.51.8-1.61.7-1.91.91.8
Intermittent access intake day 1-15 change0.10.10.3-0.20.5-0.1-0.50.10.2-0.1-0.00.00.4
Intermittent access intake escalation0.10.10.5-0.40.4-0.0-0.70.00.4-0.2-0.00.00.2
Intermittent access intake escalation 20.40.40.9-0.5-0.30.6-1.0-0.61.0-0.60.6-0.6-0.4
Intermitt. access day 1 inactive lever presses3.23.54.61.62.0-1.91.61.9-1.61.9-2.22.21.8
Intermitt. access day 15 inactive lever presses2.52.83.71.71.4-1.81.61.8-1.31.9-1.91.91.2
Intermitt. access escalation Index1.91.72.81.20.8-1.41.51.4-1.71.4-1.01.01.0
Intermittent access day 1 total infusions7.07.99.72.72.4-3.12.73.1-2.73.0-3.03.02.2
Intermittent access day 15 total infusions5.25.87.42.02.5-2.71.92.7-2.22.4-2.62.62.4
Intermittent access terminal intake (last 3 days)3.13.35.31.51.7-2.31.22.3-1.61.9-2.02.01.5
Intermittent access total infusions4.14.55.81.92.0-2.41.82.4-1.92.2-2.32.31.8
Intermittent access day 1 locomotion5.15.26.32.21.8-2.42.42.4-2.32.4-2.52.51.6
Intermittent access day 15 total locomotion2.02.13.21.31.4-1.61.21.6-1.11.6-1.81.81.0
Intermittent access total locomotion6.16.99.02.62.4-2.82.42.8-2.12.9-3.03.02.0
Intermittent access standard deviation0.50.52.3-1.20.20.1-1.5-0.10.6-0.80.1-0.1-0.2
Cocaine induced anxiety0.20.20.6-0.8-0.40.0-0.8-0.00.4-0.50.4-0.4-0.6
Post-drug Anxiety0.40.41.3-1.0-0.40.2-1.1-0.20.7-0.70.3-0.3-0.8
Baseline Anxiety0.70.81.2-0.7-0.81.1-0.8-1.11.1-0.90.6-0.6-1.0
Lifetime Intake3.43.85.11.61.9-2.31.62.3-1.82.0-2.22.21.6
Incentive Sensitization - Responses0.50.50.80.90.6-0.80.50.8-0.60.9-0.60.60.5
Incentive Sensitization - Breakpoint1.01.01.41.20.8-1.10.81.1-0.91.2-0.90.90.8
Progressive ratio test 1 active lever presses1.31.31.61.11.2-1.21.01.2-1.31.2-1.11.11.2
Progressive ratio test 1 breakpoint1.01.11.40.91.1-1.10.81.1-1.21.0-1.01.01.2
Progressive ratio test 1 inactive lever presses0.30.30.50.60.3-0.70.60.7-0.70.6-0.70.70.1
Progressive ratio test 2 active lever presses2.72.83.51.51.8-1.91.21.9-1.61.8-1.71.71.7
Progressive ratio test 2 breakpoint2.73.03.61.61.9-1.81.31.8-1.71.8-1.71.71.9
Progressive ratio test 2 inactive lever presses2.93.44.41.71.8-2.11.42.1-1.52.0-2.12.11.5
Total sessions with >9 infusions2.73.03.51.51.7-1.91.61.9-1.71.7-1.91.91.6
Short access day 1 total inactive lever presses2.12.32.61.41.4-1.61.61.6-1.51.6-1.61.61.4
Short access day 10 total inactive lever presses1.01.11.60.61.3-1.10.91.1-1.10.8-1.21.21.2
Short access day 1 total infusions1.51.52.60.91.1-1.60.91.6-1.41.2-1.31.31.0
Short access day 10 total infusions5.46.08.52.22.0-2.92.22.9-2.52.6-2.62.61.7
Short access total infusions2.32.53.61.31.4-1.91.31.9-1.61.5-1.81.81.1
Short access day 1 locomotion0.60.61.00.70.3-1.00.71.0-1.00.8-0.70.70.2
Short access day 10 total locomotion2.22.43.61.31.4-1.81.31.8-1.41.6-1.91.91.0
Short access total locomotion1.71.72.51.31.0-1.51.31.5-1.31.4-1.61.60.6
Compulsive drug intake4.24.25.7-2.2-1.82.3-1.8-2.31.7-2.41.9-1.9-1.9
One hour access (0.3 mA shock)4.65.36.51.82.5-2.51.72.5-2.12.3-2.52.52.3
One hour access (shock baseline)5.46.27.52.32.6-2.71.92.7-2.22.6-2.52.52.7
Number of responses in last shaping day0.20.20.3-0.4-0.50.3-0.3-0.30.3-0.60.5-0.5-0.6
Context. condit. distance diff. score0.20.20.50.30.5-0.60.30.6-0.70.5-0.50.50.3
Locomotion velocity, session 10.40.41.6-1.30.0-0.2-1.20.20.5-0.7-0.20.2-0.4
Locomotion distance, session 10.40.51.7-1.2-0.3-0.2-1.30.20.7-0.7-0.10.1-0.8
Locomotion velocity, session 20.60.71.8-0.6-1.10.6-0.7-0.61.0-0.70.6-0.6-1.3
Locomotion distance, session 20.50.71.7-1.3-0.70.3-1.3-0.30.8-1.00.4-0.4-1.0
Locomotion velocity, session 31.31.52.01.40.7-1.31.41.3-1.31.3-1.21.20.6
Locomotion distance, session 30.30.30.80.70.2-0.40.70.4-0.90.6-0.30.30.4
Stereotopy head waving bouts, day 30.91.01.50.80.8-1.20.91.2-1.10.9-1.21.20.7
Stereotopy head waving duration, day 30.40.40.70.70.4-0.70.80.7-0.80.6-0.60.60.3
Locomotion velocity, session 70.40.41.51.10.2-0.41.20.4-0.50.8-0.30.30.5
Locomotion distance, session 70.20.30.50.50.3-0.60.70.6-0.70.6-0.50.50.5
Stereotopy head waving bouts, day 70.00.00.0-0.0-0.1-0.10.00.10.10.1-0.00.0-0.1
Stereotopy head waving duration, day 70.40.51.2-0.3-1.10.7-0.2-0.70.5-0.40.7-0.7-1.0
Locomotion velocity, session 80.30.30.5-0.4-0.70.6-0.4-0.60.3-0.50.7-0.7-0.5
Locomotion distance, session 80.20.40.80.10.6-0.90.10.9-0.60.5-0.70.70.4
Degree of sensitization distance0.40.50.90.10.7-1.00.21.0-0.10.5-0.90.90.4
Degree of sensitization stereotypy0.30.30.6-0.4-0.70.5-0.4-0.50.7-0.40.6-0.6-0.7
Condit. Reinf. active minus inactive responses1.01.14.0-1.7-0.50.2-2.0-0.21.4-1.10.3-0.3-1.0
Condit. Reinf. active-inactive response ratio2.22.46.5-2.3-0.80.7-2.5-0.72.0-1.70.8-0.8-1.3
Condit. Reinf. active responses0.30.41.6-1.0-0.0-0.3-1.30.30.8-0.4-0.30.3-0.6
Condit. Reinf. inactive responses1.11.31.90.91.0-1.40.91.4-1.31.2-1.21.20.9
Incentive salience index mean0.30.31.3-0.9-0.1-0.2-1.10.20.6-0.3-0.30.3-0.5
Condit. Reinf. lever presses0.30.40.70.70.4-0.70.70.7-0.60.8-0.80.80.4
Time in familiar zone, hab. session 10.10.10.10.00.3-0.4-0.00.40.20.2-0.30.30.1
Time in novel zone, hab. session 10.20.20.50.10.6-0.50.10.5-0.70.3-0.30.30.7
Total zone transitions, hab. session 10.60.91.4-1.1-1.00.8-1.2-0.80.7-1.00.9-0.9-1.0
Total locomotion distance, hab. session 10.20.30.6-0.10.6-0.8-0.20.8-0.30.3-0.80.80.3
Locomotion velocity, hab. session 10.10.10.5-0.6-0.1-0.1-0.70.10.3-0.3-0.10.1-0.4
Time in familiar zone, hab. session 20.00.10.1-0.30.3-0.0-0.20.00.3-0.20.0-0.00.4
Time in novel zone, hab. session 20.00.00.2-0.1-0.3-0.1-0.20.1-0.2-0.0-0.10.1-0.4
Total zone transitions, hab. session 20.50.72.2-1.4-0.70.2-1.5-0.20.8-0.90.3-0.3-1.0
Total locomotion distance, hab. session 20.20.30.8-0.70.4-0.6-0.90.60.4-0.2-0.60.6-0.1
Locomotion velocity, hab. session 20.30.40.7-0.40.6-0.8-0.50.80.10.1-0.80.80.2
Novel to familiar place preference ratio0.50.61.60.3-1.30.80.4-0.80.0-0.20.8-0.8-1.0
Novelty place preference0.40.41.10.5-1.00.70.7-0.7-0.2-0.00.7-0.7-0.7
Time in novel zone, NPP test0.40.41.10.2-1.00.60.4-0.60.0-0.20.7-0.7-0.9
Total zone transitions, NPP test1.31.93.4-1.8-1.40.9-1.8-0.91.3-1.51.1-1.1-1.6
Total locomotion distance, NPP test0.10.20.8-0.8-0.2-0.0-0.90.00.3-0.50.0-0.0-0.4
Locomotion velocity, NPP test0.10.20.5-0.6-0.30.2-0.7-0.20.3-0.50.2-0.2-0.3
Pavlov. Cond. lever latency0.00.00.1-0.10.10.30.0-0.3-0.1-0.20.3-0.30.2
Pavlov. Cond. magazine entry latency0.10.10.10.20.0-0.30.00.30.30.3-0.30.3-0.2
Pavlov. Cond. change in total contacts0.00.10.2-0.20.1-0.2-0.30.20.40.1-0.20.2-0.0
Pavlov. Cond. index score0.00.00.2-0.1-0.10.0-0.3-0.00.40.0-0.00.0-0.2
Pavlov. Cond. latency score0.00.00.10.10.1-0.3-0.10.30.20.3-0.30.30.0
Pavlov. Cond. lever contacts0.10.10.20.30.3-0.40.20.4-0.20.4-0.50.50.3
Pavlov. Cond. magazine entry number0.30.30.90.40.5-0.50.60.5-0.90.4-0.50.50.6
Pavlov. Cond. intertrial magazine entries0.70.81.4-1.0-0.80.9-1.2-0.90.9-1.00.9-0.9-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.3-0.30.2-0.5-0.20.6-0.20.1-0.1-0.4
Pavlov. Cond. response bias0.00.10.2-0.1-0.20.1-0.3-0.10.5-0.10.1-0.1-0.3
Bone: apparent density0.20.40.80.90.4-0.60.60.6-0.40.8-0.60.60.4
Bone surface0.10.20.90.9-0.2-0.10.80.1-0.10.7-0.20.2-0.1
Bone volume0.30.61.71.30.4-0.51.00.5-0.41.0-0.60.60.4
Bone: connectivity density0.00.10.20.4-0.3-0.10.20.10.10.2-0.10.1-0.4
Bone: cortical apparent density0.91.21.4-0.8-1.11.2-1.0-1.21.2-0.91.1-1.1-1.1
Bone: cortical area0.00.00.10.2-0.30.20.1-0.20.40.00.1-0.1-0.3
Bone: cortical porosity0.50.60.8-0.6-0.70.9-0.6-0.90.6-0.80.9-0.9-0.6
Bone: cortical porosity1.21.31.6-1.0-1.11.3-0.9-1.31.0-1.21.2-1.2-1.0
Bone: cortical thickness3.15.26.0-1.8-2.52.4-1.9-2.42.4-2.22.3-2.3-2.4
Bone: cortical thickness0.70.91.2-0.5-1.01.1-0.6-1.10.9-0.91.1-1.1-1.0
Bone: cortical tissue density1.11.51.7-0.9-1.31.3-1.1-1.31.3-1.11.3-1.3-1.2
Bone: elastic displacement0.50.51.3-1.1-0.30.6-1.2-0.60.5-1.00.6-0.6-0.3
Bone: elastic work1.62.02.5-1.5-1.41.3-1.6-1.31.3-1.51.4-1.4-1.5
Bone: endosteal estimation4.49.410.82.83.0-3.22.93.2-3.23.3-3.13.12.9
Bone: endosteal perimeter5.811.813.43.43.5-3.43.53.4-3.33.7-3.53.53.5
Bone: final force0.10.20.8-0.3-0.60.2-0.3-0.20.6-0.30.2-0.2-0.9
Bone: final moment0.10.20.7-0.3-0.60.3-0.3-0.30.6-0.30.2-0.2-0.8
Bone: marrow area4.59.711.12.93.1-3.23.03.2-3.33.3-3.13.13.0
Bone: maximum diameter0.40.71.61.20.6-0.61.30.6-0.61.1-0.80.80.6
Bone: maximum force0.10.30.60.8-0.2-0.50.70.5-0.10.7-0.50.5-0.3
Bone: maximum moment0.10.20.40.6-0.2-0.40.60.4-0.00.6-0.40.4-0.3
Bone: minimum diameter3.56.47.12.32.6-2.62.32.6-2.42.6-2.72.72.5
Bone: periosteal estimation1.73.44.52.01.7-1.82.01.8-1.82.1-1.81.81.6
Bone: periosteal perimeter0.71.21.61.01.2-1.11.01.1-0.71.1-1.31.31.0
Bone: post-yield work5.37.39.32.92.4-2.72.92.7-2.63.1-2.72.72.5
Bone: stiffness0.10.20.60.80.1-0.30.70.3-0.10.6-0.30.30.1
Bone: tissue strength0.30.20.50.40.6-0.50.30.5-0.40.4-0.50.50.7
Bone: trabecular number0.10.20.70.80.1-0.40.60.4-0.20.7-0.40.40.1
Bone: trabecular spacing0.60.82.4-1.6-0.20.5-1.4-0.50.9-1.20.5-0.5-0.5
Bone: trabecular thickness0.70.91.71.30.9-0.80.90.8-0.81.1-0.80.81.1
Bone: trabecular tissue density0.70.92.60.71.3-0.80.70.8-1.00.8-0.80.81.6
Breakpoint value in progressive ratio session4.14.55.8-2.0-2.12.1-2.4-2.12.1-2.12.1-2.1-2.2
Distance traveled before self-admin0.70.71.4-0.5-0.90.8-0.8-0.81.2-0.80.7-0.7-1.1
Distance traveled after self-admin0.10.10.50.0-0.10.60.1-0.60.7-0.30.1-0.1-0.3
Delta time in closed arm before/after self-admin1.41.43.1-1.3-1.50.9-0.7-0.90.9-1.31.0-1.0-1.7
Delta time in open arm before/after self-admin1.01.01.8-0.9-1.00.9-1.3-0.91.0-0.91.0-1.0-1.1
Diff in mean of infusions in LGA sessions3.94.45.1-1.9-2.22.0-2.3-2.01.8-2.02.3-2.3-2.1
Extinction: sum of active levers before priming1.61.63.0-1.1-1.71.0-1.3-1.00.9-1.01.4-1.4-1.7
Active lever presses in extinction session 62.52.43.0-1.5-1.51.6-1.6-1.61.6-1.51.4-1.4-1.7
Delta distance traveled before/after self-admin0.20.20.40.10.6-0.30.50.3-0.50.2-0.40.40.6
Delta ambulatory time before/after self-admin0.10.10.3-0.10.5-0.20.30.2-0.20.1-0.30.30.5
Time in closed arm before self-admin0.30.30.70.90.5-0.50.40.5-0.30.8-0.50.50.7
Time in closed arm after self-admin0.20.20.50.40.4-0.70.30.7-0.50.5-0.40.40.4
Time in open arm before self-admin0.10.10.3-0.30.20.10.3-0.1-0.5-0.3-0.00.00.2
Time in open arm after self-admin1.31.42.2-1.1-0.91.5-1.0-1.51.1-1.41.2-1.2-0.9
Sum of active levers in priming session hrs 5-61.61.62.5-1.2-1.11.2-1.6-1.21.3-1.21.3-1.3-1.2
Time to tail flick, vehicle, before self-admin0.60.71.11.10.3-1.00.91.0-0.61.0-0.80.80.3
Time to tail flick, vehicle, after self-admin0.00.10.20.0-0.1-0.30.10.3-0.00.1-0.30.3-0.4
Time to tail flick, test, before self-admin0.80.82.61.10.4-0.61.60.6-0.70.9-0.80.80.5
Time to tail flick, test, after self-admin0.10.10.20.00.00.40.1-0.40.3-0.20.2-0.20.1
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.5-0.20.4-0.4-0.40.4-0.50.2-0.2-0.4
Delta time to tail flick, test, before/after SA2.22.03.2-1.5-1.01.5-1.8-1.51.4-1.61.4-1.4-1.0
Ambulatory time before self-admin0.70.81.0-0.6-0.80.9-1.0-0.90.9-0.80.8-0.8-1.0
Ambulatory time after self-admin0.30.30.50.70.6-0.30.70.30.10.6-0.70.70.4
Total heroin consumption6.07.28.4-2.3-2.92.8-2.2-2.82.6-2.72.8-2.8-2.9
Area under the delay curve0.50.51.21.00.3-0.51.10.5-0.80.8-0.60.60.5
Delay disc. indifference point, 0s delay1.92.02.91.31.2-1.51.71.5-1.31.3-1.61.61.0
Delay disc. indifference point, 16s delay0.20.20.40.50.3-0.60.50.6-0.30.6-0.60.60.3
Delay disc. indifference point, 2s delay1.82.02.61.41.2-1.41.21.4-1.31.6-1.51.51.4
Delay disc. indifference point, 24s delay0.00.00.10.3-0.00.00.3-0.0-0.30.2-0.00.00.1
Delay disc. indifference point, 4s delay0.60.62.11.2-0.2-0.31.40.3-1.10.8-0.40.40.3
Delay disc. indifference point, 8s delay0.30.31.20.90.0-0.11.10.1-0.80.6-0.10.10.6
Delay discount exponential model param0.50.51.2-1.0-0.30.5-1.1-0.50.9-0.90.6-0.6-0.6
Delay discount hyperbolic model param0.60.61.2-1.1-0.30.6-1.1-0.60.9-1.00.7-0.7-0.6
Fecal boli incidents, locomotor time 10.20.20.9-0.10.3-0.4-0.50.40.90.2-0.10.10.3
Change in fecal boli incidents, locomotor task2.01.94.21.11.2-1.11.81.1-2.01.0-1.41.41.2
Time >=10cm from walls, locomotor time 13.23.24.11.42.0-2.01.22.0-1.41.9-1.91.91.9
Bouts of movement, locomotor time 14.95.48.2-2.2-2.02.3-2.6-2.32.9-2.32.3-2.3-2.0
Total resting periods, locomotor time 13.13.45.3-1.7-1.61.8-2.1-1.82.3-1.71.8-1.8-1.6
Rest time, locomotor task time 10.10.10.50.50.4-0.20.20.2-0.00.4-0.10.10.7
Distance moved, locomotor task time 10.20.20.60.10.3-0.50.10.5-0.80.3-0.60.6-0.0
Vertical activity count, locomotor time 10.60.62.00.40.8-0.70.70.7-1.40.6-0.80.80.8
Time >=10cm from walls, locomotor time 20.00.00.1-0.30.30.0-0.3-0.00.10.10.0-0.00.3
Bouts of movement, locomotor time 23.13.46.0-2.3-1.51.3-2.1-1.32.5-2.11.4-1.4-2.0
Total resting periods, locomotor time 22.42.65.5-2.2-1.21.0-1.9-1.02.3-1.91.1-1.1-1.7
Rest time, locomotor task time 20.70.91.40.51.2-1.20.41.2-0.50.7-1.01.01.2
Distance moved, locomotor task time 20.50.61.1-0.6-0.81.0-0.7-1.00.4-0.60.9-0.9-0.7
Vertical activity count, locomotor time 20.70.81.4-0.9-0.91.2-0.6-1.20.0-1.01.0-1.0-0.5
Weight adjusted by age1.11.33.1-1.6-0.90.5-1.8-0.51.3-1.20.4-0.4-1.5
Seeking ratio, delayed vs. immediate footshock0.30.31.10.80.3-0.51.10.5-0.50.6-0.30.30.3
Locomotion in novel chamber3.54.35.51.72.1-2.41.42.4-2.22.1-2.12.12.1
Locomotion in novel chamber post-restriction0.10.10.4-0.20.5-0.4-0.20.4-0.50.0-0.20.20.6
Progressive ratio0.40.40.70.30.5-0.80.30.8-0.60.8-0.80.80.4
Food seeking constrained by brief footshock0.10.10.3-0.60.2-0.1-0.40.1-0.3-0.2-0.10.10.0
Seeking ratio, punishment vs. effort0.20.20.6-0.6-0.30.5-0.3-0.50.3-0.80.5-0.5-0.4
Run reversals in cocaine runway, females0.50.51.60.9-0.0-0.51.30.5-0.80.7-0.50.50.2
Run reversals in cocaine runway, males0.30.20.90.40.20.00.8-0.0-1.00.40.1-0.10.7
Latency to leave start box in cocaine runway3.63.95.32.11.6-2.12.02.1-2.22.3-1.81.81.7
Latency to leave start box in cocaine runway, F0.80.91.51.20.5-0.91.10.9-0.91.1-0.80.80.6
Latency to leave start box in cocaine runway, M3.53.34.41.71.9-1.81.71.8-2.02.0-1.61.62.1
Cd content in liver0.50.51.1-0.11.1-0.8-0.10.8-0.20.3-0.90.90.9
Co content in liver0.20.20.5-0.70.20.4-0.6-0.40.3-0.60.4-0.40.1
Cu content in liver0.30.30.6-0.1-0.70.8-0.0-0.80.1-0.40.7-0.7-0.7
Fe content in liver0.00.00.00.10.10.00.0-0.0-0.2-0.0-0.10.1-0.1
K content in liver0.30.30.80.90.2-0.40.80.4-0.40.7-0.50.50.2
Mg content in liver0.60.71.20.40.7-1.10.41.1-0.50.8-1.11.10.5
Mn content in liver0.30.41.00.3-1.00.70.2-0.70.5-0.20.6-0.6-0.8
Na content in liver0.10.10.3-0.5-0.1-0.0-0.50.00.4-0.3-0.00.0-0.3
Rb content in liver1.41.82.51.01.6-1.41.11.4-1.51.2-1.41.41.5
Se content in liver0.10.10.40.6-0.30.00.6-0.0-0.00.3-0.00.0-0.2
Sr content in liver4.74.37.0-2.1-2.41.8-1.9-1.82.0-2.11.8-1.8-2.6
Zn content in liver2.02.23.9-1.7-1.61.1-1.7-1.11.8-1.51.0-1.0-2.0