Hub : Genes

Pex11g

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000028100 0.03 0.02 3.9e-03 0.01 0.02 0 0.01 3.5e-02 4.9e-03 7.7e-02 3.1e-02
2 BLA gene expression ENSRNOG00000028100 0.17 0.08 1.8e-07 0.1 0.12 0.1 0.11 5.6e-06 8.8e-07 7.1e-06 1.7e-06
3 Brain alternative polyA ENSRNOT00000037564 0.03 0.02 7.1e-04 0.01 0.03 0.01 0.02 1.6e-02 8.8e-04 3.2e-02 6.2e-03
4 Brain alternative polyA ENSRNOT00000037564 0.04 0.02 8.2e-05 0.02 0.04 0.02 0.03 3.7e-03 1.4e-04 2.8e-03 5.6e-04
5 Brain alternative polyA ENSRNOT00000110489 0.04 0.02 8.8e-05 0.02 0.04 0.02 0.03 4.0e-03 1.5e-04 2.8e-03 6.0e-04
6 Brain gene expression ENSRNOG00000028100 0.15 0.07 1.1e-16 0.14 0.18 0.17 0.17 4.7e-13 2.0e-16 5.7e-16 1.1e-15
7 Liver gene expression ENSRNOG00000028100 0.07 0.04 2.5e-06 0.04 0.04 0.04 0.04 6.7e-05 8.7e-06 2.7e-05 4.7e-05
8 Liver isoform ratio ENSRNOT00000110489 0.03 0.02 1.3e-03 0.01 0.02 0.01 0.01 7.0e-02 5.4e-03 4.0e-02 1.4e-02
9 Liver intron excision ratio chr12:1506952:1508464 0.03 0.02 2.2e-03 0.01 0.01 0 0 2.7e-02 3.7e-02 2.3e-01 1.1e-01
10 Liver intron excision ratio chr12:1508642:1510313 0.03 0.02 3.9e-03 0.01 0.01 0 0.01 4.6e-02 2.6e-02 8.2e-02 5.7e-02
11 NAcc gene expression ENSRNOG00000028100 0.07 0.04 1.3e-06 0.07 0.09 0.08 0.09 4.9e-06 5.9e-07 2.1e-06 5.3e-07
12 PL alternative polyA ENSRNOT00000037564 0.05 0.03 1.8e-03 0.01 0.03 0.03 0.02 7.7e-02 2.5e-03 3.3e-03 1.2e-02
13 PL alternative polyA ENSRNOT00000037564 0.04 0.03 2.1e-03 0.02 0.03 0.03 0.02 2.0e-02 2.8e-03 3.3e-03 1.6e-02
14 PL alternative polyA ENSRNOT00000110489 0.04 0.03 1.9e-03 0.02 0.03 0.03 0.02 2.0e-02 2.2e-03 1.6e-03 1.7e-02
15 PL gene expression ENSRNOG00000028100 0.13 0.07 4.9e-08 0.06 0.1 0.1 0.1 2.9e-05 1.1e-07 1.2e-07 5.3e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.93.09.1-1.9-2.8-0.5-0.50.5-2.6-2.70.4-1.81.2-1.51.20.4-0.6-3.0
BMI without tail1.53.27.5-2.3-2.7-0.5-0.60.6-2.5-2.60.4-2.51.6-1.91.30.6-0.9-2.4
Body weight3.816.233.6-3.7-5.81.41.1-1.1-4.9-5.3-1.2-5.81.8-2.95.74.0-4.2-5.3
Epididymis fat weight0.30.61.5-0.3-0.7-0.8-0.80.8-0.6-0.81.2-0.50.8-0.6-0.8-0.91.0-0.7
Glucose0.30.50.8-0.8-0.6-0.9-0.90.9-0.7-0.50.40.20.5-0.5-0.7-0.80.7-0.8
Heart weight0.50.82.6-0.50.3-0.6-0.80.80.10.11.0-1.61.1-1.4-1.0-0.60.70.9
Left kidney weight2.26.420.0-1.9-2.91.51.2-1.2-2.4-2.7-1.0-4.51.1-1.73.93.2-3.2-2.1
Right kidney weight2.05.615.1-1.7-2.71.61.3-1.3-2.2-2.5-1.3-3.70.7-1.33.93.1-3.2-2.1
Tail length2.36.920.7-3.0-3.80.2-0.10.1-3.3-3.60.1-4.62.1-2.72.81.9-2.0-2.9
Length with tail4.115.140.7-3.6-5.31.51.1-1.1-4.4-4.9-1.0-6.42.1-3.15.44.0-4.1-4.4
Length without tail2.55.512.0-1.9-3.41.00.8-0.8-2.8-3.1-0.7-3.50.9-1.53.42.4-2.3-3.3
Liver weight, left2.13.45.71.61.02.42.3-2.41.31.2-2.10.5-1.81.62.32.4-2.21.2
Liver weight, right0.71.13.6-0.1-0.91.21.0-1.0-0.5-0.8-0.6-1.60.0-0.21.91.6-1.5-0.4
Parametrial fat weight0.50.92.30.20.11.11.1-1.10.20.3-1.50.3-1.00.71.51.4-1.5-0.2
Retroperitoneal fat weight0.92.95.9-0.9-1.2-2.2-2.01.9-1.3-1.31.80.61.0-0.8-2.0-2.42.4-2.2
Intraocular pressure0.20.21.40.1-0.40.50.4-0.4-0.2-0.40.2-1.20.3-0.20.60.6-0.4-0.0
Extensor digitorum longus weight1.24.917.2-2.0-3.20.30.0-0.0-2.7-3.10.5-4.21.8-2.22.31.5-1.3-2.6
Soleus weight0.20.52.60.0-0.70.70.6-0.6-0.4-0.70.1-1.60.3-0.41.11.0-0.7-0.3
Tibialis anterior weight2.07.020.2-2.7-4.0-0.1-0.30.3-3.5-3.90.7-4.52.3-2.62.41.4-1.3-3.4
Tibia length1.64.614.4-1.6-2.31.61.4-1.4-1.8-1.8-2.1-1.9-0.1-0.53.83.0-3.3-2.2
Number of licking bursts1.82.15.80.20.51.71.6-1.60.60.7-2.2-0.1-1.10.82.12.2-2.40.8
Food consumed during 24 hour testing period0.70.91.40.70.61.21.1-1.10.70.7-1.10.1-0.90.81.11.2-1.10.9
Times rat made contact with spout0.50.61.8-1.0-1.0-0.2-0.20.2-0.9-0.90.0-1.40.7-0.90.50.3-0.4-0.8
Mean time between licks in bursts0.60.81.91.11.4-0.00.1-0.11.21.30.11.4-0.60.9-1.0-0.60.71.2
Mean num. licks in bursts0.70.81.8-0.4-0.7-1.0-1.01.0-0.7-0.81.3-0.40.9-0.7-1.1-1.21.3-0.7
Std. dev. time between licks in bursts0.20.20.8-0.2-0.1-0.4-0.50.5-0.1-0.30.9-0.60.7-0.4-0.6-0.50.60.1
Water consumed over 24 hours1.01.23.7-0.2-0.31.31.1-1.1-0.1-0.2-1.2-1.2-0.30.01.91.8-1.80.2
Indifference point 0 sec2.03.24.82.21.82.02.0-2.02.01.8-1.51.2-1.91.91.21.5-1.41.9
Indifference point AUC0.20.30.9-0.1-0.20.60.5-0.5-0.1-0.2-0.4-0.6-0.0-0.00.90.9-0.80.1
Indifference point function ln k0.10.20.80.50.70.40.3-0.30.60.6-0.1-0.0-0.20.2-0.00.2-0.20.9
Indifference point function log k0.10.20.80.50.70.40.3-0.30.60.6-0.1-0.0-0.20.2-0.00.2-0.20.9
Delay discounting total patch changes 0 sec2.54.16.32.52.22.22.2-2.22.32.2-1.61.3-2.12.21.21.6-1.42.3
Delay discounting total patch changes 12 sec0.91.21.91.30.81.31.4-1.40.90.8-1.00.8-1.21.31.11.2-1.00.7
Delay discounting total patch changes 18 sec2.73.65.02.11.82.22.2-2.21.91.8-1.81.0-2.02.01.61.9-1.72.0
Delay discounting total patch changes 24 sec1.21.65.11.81.71.11.1-1.11.81.6-0.20.5-0.91.20.00.5-0.22.2
Delay discounting total patch changes 6 sec1.52.43.41.91.41.81.8-1.81.61.4-1.30.7-1.61.61.31.5-1.41.6
Delay discounting time to switch 0 sec0.60.93.4-0.8-0.8-1.1-0.90.9-0.9-0.70.11.5-0.0-0.0-0.7-1.10.8-1.9
Delay discounting water rate 0 sec1.62.54.81.51.22.11.9-1.91.41.1-1.0-1.3-0.80.81.72.1-1.72.2
Delay discounting water rate 12 sec0.20.31.80.60.70.30.2-0.20.70.50.5-0.80.20.1-0.30.10.11.3
Delay discounting water rate 18 sec0.91.22.8-0.40.0-1.1-1.21.2-0.1-0.21.7-1.01.3-0.9-1.6-1.31.50.5
Delay discounting water rate 24 sec0.30.42.70.10.00.60.4-0.40.1-0.10.1-1.60.4-0.50.60.7-0.60.7
Delay discounting water rate 6 sec0.20.31.40.80.60.30.2-0.20.70.40.7-0.70.2-0.0-0.3-0.00.41.2
Locomotor activity1.11.86.5-1.6-1.5-0.7-0.90.9-1.4-1.61.1-2.51.9-1.90.0-0.10.1-0.8
Locomotor testing distance0.20.41.00.30.10.90.8-0.80.30.1-0.4-0.7-0.10.00.91.0-1.00.6
Locomotor testing rearing0.61.01.91.41.21.01.0-1.01.21.1-0.60.8-1.11.10.40.7-0.61.2
Light reinforcement 11.42.54.0-1.4-0.9-2.0-2.02.0-1.2-1.11.7-0.41.6-1.5-1.9-2.01.9-1.2
Light reinforcement 20.20.30.60.40.70.40.5-0.50.60.7-0.60.8-0.60.50.20.4-0.40.6
Reaction time number correct0.70.91.60.90.81.31.2-1.20.90.8-0.8-0.5-0.70.61.01.2-1.01.3
Reaction time mean minus median6.48.411.4-2.6-2.6-3.2-3.23.2-2.8-2.83.4-2.23.3-2.9-2.5-2.92.8-2.6
Reaction time mean minus median AUC2.73.46.2-1.2-1.0-2.2-2.22.2-1.2-1.22.5-1.02.0-1.6-2.3-2.42.4-0.8
Reaction time num false alarms2.02.74.5-1.3-0.9-1.9-2.02.0-1.1-1.12.1-1.11.9-1.7-2.0-2.02.0-0.6
Reaction time num false alarms AUC1.52.04.0-0.9-0.7-1.6-1.71.7-0.9-0.92.0-0.91.7-1.4-1.8-1.71.8-0.4
Reaction time trials correct on left0.70.91.60.90.81.31.2-1.20.90.8-0.8-0.5-0.70.61.01.2-1.01.3
Reaction time trials on left0.60.81.40.80.71.21.1-1.10.80.7-0.7-0.6-0.60.60.91.2-1.01.2
Reaction time mean2.73.77.3-1.5-1.0-2.6-2.52.5-1.3-1.12.00.41.6-1.3-2.6-2.72.5-1.4
Reaction time mean AUC2.73.67.5-1.3-0.8-2.5-2.42.4-1.1-0.92.10.51.6-1.2-2.7-2.72.6-1.2
Median of all reaction times1.72.25.5-0.9-0.2-2.1-1.91.9-0.6-0.31.31.30.8-0.6-2.3-2.32.1-0.8
Reaction time omissions1.72.34.4-1.0-0.7-2.0-1.91.9-0.9-0.81.9-0.31.5-0.9-2.1-2.12.0-0.8
Reaction time false alarm rate2.23.25.2-1.3-1.1-2.1-2.12.1-1.3-1.32.3-0.81.9-1.7-2.1-2.22.2-1.0
Reaction time premature initiation rate0.81.01.4-1.1-0.9-1.2-1.21.2-1.0-0.91.1-0.71.2-1.0-0.9-1.01.0-0.8
Reaction time premature initiations0.20.30.7-0.6-0.4-0.5-0.60.6-0.5-0.50.7-0.80.8-0.6-0.4-0.40.5-0.2
Std. dev. reaction times3.85.37.8-1.9-1.7-2.8-2.82.8-2.0-1.92.7-1.02.4-2.0-2.5-2.72.6-1.9
Reaction time trials completed0.60.81.40.80.71.21.1-1.10.80.7-0.7-0.6-0.60.60.91.2-1.01.2
Reaction time trials AUC0.50.81.70.90.81.11.0-1.00.90.8-0.6-0.4-0.60.60.71.0-0.71.3
Social response proportion4.24.510.4-2.9-2.9-1.2-1.41.4-2.8-2.80.9-3.22.3-2.60.6-0.0-0.3-2.5
Social responses0.91.15.0-1.1-1.2-0.5-0.60.6-1.1-1.31.0-2.21.4-1.30.1-0.10.1-0.7
Social time1.11.44.3-0.50.2-1.6-1.51.5-0.10.11.30.40.9-0.4-2.1-1.91.70.0
Conditioned locomotion0.40.51.31.10.70.70.8-0.80.80.7-0.30.8-0.80.90.30.4-0.30.6
Cocaine response after cond. corrected0.50.51.20.2-0.20.60.7-0.7-0.1-0.0-1.11.1-0.90.71.00.7-0.8-0.8
Cocaine response after cond. not corrected0.20.21.3-0.2-0.7-0.2-0.10.1-0.6-0.60.00.6-0.10.10.2-0.20.1-1.1
Cocaine response before conditioning1.92.35.4-0.8-0.9-1.6-1.71.7-1.0-1.12.3-1.21.8-1.4-1.8-1.82.0-0.5
Saline control response0.60.82.4-0.1-0.11.00.8-0.80.0-0.1-0.6-1.60.1-0.21.41.4-1.40.6
Condit. Reinf. active minus inactive responses2.43.06.0-2.2-2.0-1.4-1.51.6-2.1-2.11.3-2.52.1-2.2-0.4-0.70.6-1.7
Condit. Reinf. active-inactive response ratio2.42.64.5-2.1-1.7-1.5-1.61.6-1.8-1.71.2-1.91.9-2.0-0.7-1.00.8-1.4
Condit. Reinf. active responses2.73.87.0-2.2-2.2-1.7-1.81.8-2.2-2.31.8-2.62.4-2.4-0.7-1.11.1-1.8
Condit. Reinf. inactive responses0.20.20.8-0.2-0.5-0.3-0.40.3-0.4-0.60.8-0.90.6-0.5-0.2-0.30.4-0.3
Condit. Reinf. lever presses0.60.91.7-0.6-0.8-0.9-0.90.9-0.8-0.91.3-1.11.1-0.9-0.8-0.91.0-0.6
Condit. Reinf. lever reinforcers received2.73.86.3-2.1-2.0-1.8-1.91.9-2.1-2.12.0-2.52.4-2.3-1.0-1.31.3-1.7
Pavlov. Cond. lever latency2.43.34.81.51.32.12.1-2.11.51.5-2.21.5-2.02.01.92.0-2.11.2
Pavlov. Cond. magazine entry latency3.03.56.1-1.4-1.1-2.4-2.32.3-1.3-1.22.2-0.51.8-1.5-2.4-2.52.4-1.3
Pavlov. Cond. change in total contacts1.31.72.8-1.0-0.7-1.5-1.61.6-0.8-0.81.7-1.21.5-1.4-1.6-1.51.6-0.5
Pavlov. Cond. index score2.73.55.8-1.3-0.9-2.3-2.32.3-1.2-1.22.3-1.02.0-1.8-2.3-2.42.4-0.9
Pavlov. Cond. latency score2.63.25.5-1.3-0.9-2.2-2.22.2-1.2-1.12.3-0.91.9-1.6-2.3-2.32.3-1.0
Pavlov. Cond. lever contacts2.13.04.9-1.2-1.1-2.0-2.02.0-1.3-1.32.2-1.11.8-1.7-2.0-2.12.2-1.1
Pavlov. Cond. magazine entry number2.32.85.61.10.62.12.1-2.10.90.8-2.00.5-1.61.42.42.3-2.30.7
Pavlov. Cond. intertrial magazine entries0.20.20.60.0-0.00.60.5-0.50.1-0.0-0.4-0.6-0.1-0.00.80.8-0.80.3
Pavlov. Cond. lever-magazine prob. diff.2.83.65.9-1.4-0.9-2.3-2.32.3-1.2-1.22.4-1.02.0-1.8-2.4-2.42.4-0.9
Pavlov. Cond. response bias3.34.57.9-1.4-1.1-2.6-2.62.5-1.3-1.42.8-1.22.2-2.0-2.7-2.72.8-1.1
Conditioned reinforcement - actives1.31.35.1-1.2-1.30.40.2-0.2-1.1-1.2-0.3-2.30.8-1.21.41.2-1.2-0.7
Conditioned reinforcement - inactives0.70.81.40.60.61.11.1-1.10.70.7-1.00.1-0.70.51.11.2-1.10.9
Conditioned locomotion0.60.74.2-0.7-0.90.1-0.10.1-0.8-1.00.4-2.00.9-1.10.60.5-0.2-0.3
Intermittent access intake day 1-15 change1.41.43.30.60.51.61.5-1.50.60.6-1.5-0.2-0.90.81.81.8-1.50.7
Intermittent access intake escalation0.70.71.80.30.21.11.0-1.00.30.2-0.9-0.5-0.50.41.31.4-1.00.6
Intermittent access intake escalation 20.40.40.70.70.60.80.7-0.70.70.6-0.60.2-0.60.60.50.7-0.40.9
Intermitt. access day 1 inactive lever presses1.31.52.41.01.11.41.4-1.41.21.2-1.20.3-1.00.91.11.4-1.41.5
Intermitt. access day 15 inactive lever presses1.31.52.61.10.81.31.4-1.40.90.9-1.51.6-1.61.41.21.2-1.00.3
Intermitt. access escalation Index0.50.41.30.10.3-0.6-0.60.60.20.11.0-0.40.5-0.3-1.1-0.91.10.6
Intermittent access day 1 total infusions1.21.33.4-0.5-0.1-1.4-1.41.4-0.3-0.21.5-0.11.0-0.9-1.8-1.71.80.1
Intermittent access day 15 total infusions0.10.10.40.20.30.0-0.00.00.30.30.3-0.20.2-0.1-0.3-0.10.40.7
Intermittent access terminal intake (last 3 days)0.10.10.20.30.4-0.1-0.10.10.30.30.20.4-0.00.1-0.4-0.30.50.4
Intermittent access total infusions0.60.71.8-0.3-0.1-1.0-1.01.0-0.3-0.21.10.10.7-0.6-1.3-1.21.3-0.1
Intermittent access day 1 locomotion2.52.67.5-0.20.1-1.9-1.81.8-0.2-0.22.20.31.2-0.8-2.7-2.52.70.1
Intermittent access day 15 total locomotion1.31.33.3-0.3-0.0-1.2-1.31.3-0.1-0.31.8-0.91.3-1.1-1.7-1.51.80.6
Intermittent access total locomotion2.42.87.4-0.4-0.0-1.9-1.91.9-0.3-0.32.4-0.31.5-1.2-2.6-2.42.70.3
Intermittent access standard deviation2.22.33.51.20.91.81.9-1.91.11.0-1.91.1-1.71.61.81.8-1.80.7
Cocaine induced anxiety0.91.02.7-0.1-0.1-1.2-1.11.1-0.3-0.31.5-0.10.8-0.6-1.6-1.51.6-0.1
Post-drug Anxiety2.52.86.8-0.7-0.4-2.2-2.12.1-0.7-0.51.90.51.2-1.0-2.6-2.62.5-0.7
Baseline Anxiety0.70.71.8-0.6-0.2-1.2-1.11.1-0.4-0.10.41.20.2-0.2-1.2-1.31.1-0.8
Lifetime Intake0.30.30.9-0.3-0.1-0.8-0.70.7-0.2-0.20.60.40.4-0.3-0.9-0.90.9-0.4
Incentive Sensitization - Responses0.40.40.9-0.20.0-0.6-0.70.7-0.1-0.10.9-0.70.7-0.7-0.9-0.71.00.4
Incentive Sensitization - Breakpoint0.40.41.1-0.20.1-0.6-0.70.7-0.0-0.10.9-0.70.7-0.7-0.9-0.81.00.5
Progressive ratio test 1 active lever presses0.10.10.3-0.4-0.30.10.1-0.0-0.3-0.3-0.2-0.60.2-0.50.40.4-0.4-0.2
Progressive ratio test 1 breakpoint0.20.20.4-0.6-0.50.10.0-0.0-0.5-0.4-0.3-0.60.3-0.50.50.4-0.5-0.4
Progressive ratio test 1 inactive lever presses0.30.30.80.10.30.70.6-0.60.30.3-0.5-0.7-0.1-0.10.70.9-0.90.9
Progressive ratio test 2 active lever presses0.50.62.3-0.9-0.7-0.4-0.60.6-0.7-0.70.6-1.51.1-1.3-0.1-0.10.2-0.1
Progressive ratio test 2 breakpoint0.70.72.0-1.0-0.6-0.7-0.80.8-0.7-0.70.8-1.41.2-1.4-0.5-0.40.6-0.1
Progressive ratio test 2 inactive lever presses0.91.02.10.70.61.31.2-1.20.80.6-0.7-1.0-0.30.11.21.5-1.21.4
Total sessions with >9 infusions0.20.20.3-0.5-0.5-0.5-0.50.5-0.5-0.50.4-0.30.5-0.5-0.3-0.40.5-0.6
Short access day 1 total inactive lever presses0.40.40.50.50.60.70.7-0.70.60.6-0.70.4-0.60.60.50.7-0.70.7
Short access day 10 total inactive lever presses2.22.45.01.00.52.02.0-2.00.80.7-1.80.2-1.31.12.22.2-2.20.7
Short access day 1 total infusions0.80.93.41.01.00.60.7-0.70.91.0-0.91.9-1.31.30.10.2-0.20.3
Short access day 10 total infusions0.20.30.80.40.4-0.4-0.40.40.30.40.40.8-0.10.2-0.9-0.80.70.1
Short access total infusions0.10.11.1-0.1-0.1-0.2-0.10.1-0.2-0.0-0.31.0-0.30.3-0.1-0.20.1-0.8
Short access day 1 locomotion1.71.83.6-1.0-0.5-1.8-1.71.7-0.7-0.61.5-0.11.2-1.1-1.9-1.91.8-0.5
Short access day 10 total locomotion0.40.41.01.00.90.10.1-0.10.90.80.21.0-0.50.7-0.7-0.40.60.9
Short access total locomotion0.70.71.9-0.2-0.1-1.1-1.01.0-0.2-0.20.90.60.4-0.3-1.4-1.41.4-0.4
Compulsive drug intake0.90.92.21.01.5-0.00.0-0.01.31.4-0.11.4-0.70.8-1.0-0.60.51.4
One hour access (0.3 mA shock)0.30.42.60.61.00.40.3-0.30.90.9-0.0-0.3-0.10.0-0.10.3-0.21.6
One hour access (shock baseline)0.50.52.8-0.6-0.7-0.3-0.50.5-0.6-0.80.8-1.71.1-1.1-0.1-0.10.2-0.0
Number of responses in last shaping day0.10.10.20.30.40.30.3-0.30.40.4-0.30.0-0.30.20.20.3-0.20.5
Context. condit. distance diff. score2.02.46.6-1.5-2.1-0.9-1.01.0-1.9-2.11.5-2.61.8-1.9-0.0-0.40.5-1.7
Locomotion velocity, session 10.60.71.4-0.5-0.3-1.1-1.01.0-0.4-0.31.0-0.20.8-0.6-1.2-1.21.1-0.3
Locomotion distance, session 10.40.51.80.10.6-0.7-0.70.70.40.50.70.60.3-0.0-1.3-1.11.10.5
Locomotion velocity, session 20.20.30.5-0.7-0.2-0.7-0.70.7-0.4-0.30.3-0.20.6-0.7-0.5-0.50.4-0.2
Locomotion distance, session 20.40.61.80.31.0-0.5-0.60.60.80.80.60.60.2-0.1-1.3-0.90.91.2
Locomotion velocity, session 30.30.40.6-0.5-0.7-0.6-0.60.6-0.6-0.70.8-0.60.7-0.6-0.4-0.50.6-0.5
Locomotion distance, session 30.30.41.00.90.80.50.5-0.50.80.8-0.20.4-0.50.70.00.2-0.11.0
Stereotopy head waving bouts, day 30.70.93.00.1-0.41.21.1-1.1-0.2-0.3-0.9-0.7-0.40.21.71.6-1.5-0.1
Stereotopy head waving duration, day 30.10.10.30.20.10.40.5-0.50.10.1-0.50.3-0.40.30.50.5-0.5-0.0
Locomotion velocity, session 72.12.33.3-1.7-1.3-1.8-1.81.8-1.5-1.41.3-1.01.6-1.4-1.3-1.51.4-1.5
Locomotion distance, session 71.31.62.4-1.2-0.8-1.5-1.51.5-1.0-1.01.5-1.21.5-1.3-1.3-1.41.3-0.8
Stereotopy head waving bouts, day 70.30.31.10.20.5-0.5-0.50.50.30.40.60.50.20.0-1.0-0.80.90.5
Stereotopy head waving duration, day 70.10.20.60.20.4-0.4-0.30.30.30.40.30.6-0.00.1-0.7-0.60.60.3
Locomotion velocity, session 80.60.71.4-1.2-1.0-0.8-0.80.8-1.1-1.00.5-0.70.9-1.0-0.2-0.40.3-1.0
Locomotion distance, session 80.81.22.4-1.2-1.4-0.7-0.80.8-1.3-1.40.9-1.61.3-1.4-0.0-0.30.3-1.2
Degree of sensitization distance1.11.11.9-1.1-0.5-1.4-1.41.4-0.7-0.60.9-0.41.1-1.1-1.2-1.31.1-0.7
Degree of sensitization stereotypy0.30.30.9-0.10.1-0.7-0.70.7-0.0-0.00.70.40.4-0.2-1.0-0.90.90.0
Condit. Reinf. active minus inactive responses0.50.51.3-0.3-0.2-1.0-0.90.9-0.3-0.30.80.40.5-0.2-1.1-1.11.1-0.4
Condit. Reinf. active-inactive response ratio0.70.71.2-0.7-0.7-1.1-1.01.0-0.8-0.70.9-0.10.7-0.6-0.9-1.11.1-1.0
Condit. Reinf. active responses0.60.71.9-0.2-0.0-1.0-1.01.0-0.2-0.21.20.10.7-0.4-1.4-1.31.3-0.0
Condit. Reinf. inactive responses0.60.72.30.10.5-0.8-0.90.90.30.31.10.10.6-0.4-1.5-1.21.30.7
Incentive salience index mean0.60.72.00.00.1-1.0-0.90.9-0.0-0.01.10.30.5-0.2-1.4-1.31.40.0
Condit. Reinf. lever presses0.50.62.00.20.2-0.8-0.80.80.10.01.30.10.6-0.3-1.4-1.21.40.3
Time in familiar zone, hab. session 11.71.62.61.41.21.21.3-1.31.31.3-1.31.6-1.61.60.80.9-0.90.9
Time in novel zone, hab. session 10.80.81.5-1.1-1.1-0.7-0.80.8-1.1-1.10.7-1.21.0-1.2-0.2-0.40.2-1.0
Total zone transitions, hab. session 11.01.44.2-0.40.2-1.5-1.51.5-0.1-0.01.50.21.0-0.8-2.0-1.81.80.1
Total locomotion distance, hab. session 10.81.22.7-0.4-0.3-1.4-1.31.3-0.4-0.41.40.10.9-0.7-1.6-1.61.6-0.5
Locomotion velocity, hab. session 11.31.84.8-0.4-0.1-1.7-1.61.6-0.3-0.31.70.31.1-0.8-2.2-2.12.1-0.3
Time in familiar zone, hab. session 20.10.10.20.1-0.10.20.3-0.3-0.1-0.0-0.40.4-0.40.40.30.2-0.2-0.4
Time in novel zone, hab. session 20.30.30.9-0.20.1-0.6-0.70.70.00.00.7-0.20.6-0.5-0.9-0.80.70.3
Total zone transitions, hab. session 20.10.10.4-0.7-0.3-0.2-0.20.2-0.3-0.3-0.0-0.50.4-0.50.10.1-0.3-0.1
Total locomotion distance, hab. session 20.10.20.4-0.30.0-0.5-0.50.5-0.1-0.00.5-0.00.4-0.4-0.6-0.50.50.0
Locomotion velocity, hab. session 20.10.10.3-0.30.1-0.4-0.40.5-0.00.00.3-0.00.4-0.3-0.5-0.40.40.1
Novel to familiar place preference ratio0.10.10.3-0.5-0.2-0.3-0.30.3-0.2-0.1-0.0-0.30.3-0.4-0.1-0.1-0.1-0.1
Novelty place preference0.10.10.2-0.40.0-0.3-0.40.4-0.10.00.1-0.10.3-0.3-0.3-0.30.10.0
Time in novel zone, NPP test0.10.10.2-0.5-0.1-0.3-0.30.3-0.2-0.10.0-0.20.3-0.4-0.2-0.20.0-0.1
Total zone transitions, NPP test0.20.40.6-0.6-0.5-0.6-0.70.7-0.5-0.50.7-0.60.8-0.8-0.5-0.50.5-0.3
Total locomotion distance, NPP test1.52.03.4-1.0-1.0-1.7-1.71.7-1.1-1.11.9-0.71.5-1.4-1.6-1.71.7-1.0
Locomotion velocity, NPP test1.42.03.5-1.0-0.9-1.6-1.61.6-1.0-1.11.9-0.91.6-1.5-1.6-1.61.6-0.8
Pavlov. Cond. lever latency1.01.34.3-0.1-0.51.31.2-1.2-0.2-0.3-1.3-1.1-0.50.12.11.9-1.9-0.3
Pavlov. Cond. magazine entry latency0.30.40.6-0.8-0.7-0.6-0.60.6-0.7-0.70.6-0.70.8-0.8-0.2-0.30.3-0.5
Pavlov. Cond. change in total contacts1.51.62.5-1.2-1.1-1.6-1.51.5-1.2-1.11.3-0.21.2-1.0-1.3-1.51.4-1.3
Pavlov. Cond. index score0.60.71.2-0.6-0.5-1.0-1.01.0-0.6-0.61.1-0.10.9-0.7-1.0-1.11.1-0.6
Pavlov. Cond. latency score0.81.12.0-0.7-0.5-1.3-1.31.3-0.7-0.61.3-0.01.0-0.8-1.4-1.41.4-0.6
Pavlov. Cond. lever contacts0.81.03.1-0.00.2-1.2-1.11.10.00.11.20.80.5-0.2-1.7-1.61.7-0.0
Pavlov. Cond. magazine entry number0.70.81.40.80.90.80.9-0.90.91.0-1.11.2-1.21.10.50.7-0.70.6
Pavlov. Cond. intertrial magazine entries0.50.61.40.91.20.20.2-0.21.11.1-0.11.1-0.60.9-0.6-0.30.31.1
Pavlov. Cond. lever-magazine prob. diff.0.40.50.8-0.5-0.5-0.8-0.80.8-0.5-0.50.90.00.7-0.5-0.8-0.90.9-0.5
Pavlov. Cond. response bias0.50.61.1-0.6-0.6-0.9-0.90.9-0.7-0.71.1-0.50.9-0.8-0.8-0.90.9-0.5
Bone: apparent density1.52.57.01.0-0.22.22.1-2.10.3-0.0-1.4-0.9-1.10.82.62.4-2.10.2
Bone surface1.11.96.7-0.0-1.31.51.4-1.4-0.8-1.1-0.9-1.5-0.3-0.02.62.1-1.9-1.1
Bone volume0.91.54.50.8-0.41.71.6-1.6-0.0-0.3-1.0-0.5-0.90.72.11.8-1.6-0.3
Bone: connectivity density1.42.37.60.1-1.01.81.6-1.6-0.6-0.9-1.1-1.9-0.3-0.12.82.4-2.2-0.5
Bone: cortical apparent density0.60.81.3-0.9-0.6-1.2-1.11.1-0.8-0.60.80.00.8-0.7-1.0-1.11.0-0.8
Bone: cortical area1.42.24.6-1.7-2.2-0.8-0.90.9-2.0-2.10.9-2.11.5-1.60.3-0.20.1-2.1
Bone: cortical porosity0.10.10.10.20.20.40.4-0.40.20.2-0.30.0-0.30.30.40.4-0.40.2
Bone: cortical porosity0.10.10.30.10.2-0.3-0.30.30.20.20.5-0.10.2-0.0-0.6-0.50.50.3
Bone: cortical thickness1.01.74.0-1.6-2.0-0.5-0.60.6-1.8-1.90.6-1.91.3-1.40.60.1-0.2-1.9
Bone: cortical thickness0.50.62.4-1.0-1.0-0.2-0.30.3-0.9-1.00.3-1.50.9-1.00.40.3-0.3-0.6
Bone: cortical tissue density0.40.51.0-0.7-0.4-1.0-1.01.0-0.6-0.50.70.20.6-0.5-0.9-1.00.9-0.6
Bone: elastic displacement0.20.20.80.1-0.10.60.6-0.6-0.0-0.1-0.5-0.3-0.20.10.90.8-0.80.0
Bone: elastic work0.81.13.5-0.3-0.91.11.0-1.0-0.6-0.8-0.7-1.50.0-0.31.91.6-1.5-0.5
Bone: endosteal estimation0.61.32.80.80.41.51.4-1.40.60.5-1.1-0.5-0.80.61.61.7-1.60.8
Bone: endosteal perimeter0.10.21.8-0.0-0.40.20.1-0.1-0.3-0.50.4-1.30.5-0.50.30.3-0.10.0
Bone: final force1.01.64.3-1.5-1.80.20.0-0.0-1.6-1.6-0.3-2.10.9-1.21.51.0-1.2-1.6
Bone: final moment0.81.33.3-1.3-1.50.30.2-0.2-1.3-1.4-0.4-1.80.6-0.91.51.1-1.3-1.4
Bone: marrow area0.61.42.90.80.51.61.5-1.50.70.6-1.2-0.5-0.90.61.61.7-1.60.9
Bone: maximum diameter0.30.61.6-0.4-1.00.50.4-0.4-0.8-0.9-0.2-1.30.2-0.41.20.9-0.8-0.8
Bone: maximum force0.61.03.2-0.8-1.20.50.4-0.4-1.0-1.1-0.3-1.80.5-0.71.41.1-1.1-1.0
Bone: maximum moment0.50.82.2-0.6-1.00.70.5-0.5-0.7-0.9-0.5-1.50.2-0.41.51.2-1.2-0.7
Bone: minimum diameter0.00.00.00.10.20.20.2-0.20.20.2-0.1-0.1-0.10.20.10.2-0.20.2
Bone: periosteal estimation0.40.72.6-0.6-1.00.50.4-0.4-0.8-1.0-0.2-1.60.4-0.61.31.0-1.0-0.7
Bone: periosteal perimeter0.81.43.4-0.9-1.3-0.9-1.01.0-1.2-1.41.5-1.81.5-1.4-0.6-0.70.9-1.0
Bone: post-yield work0.00.00.20.40.00.30.3-0.30.1-0.00.2-0.2-0.10.20.10.10.00.1
Bone: stiffness0.71.03.0-1.2-1.2-0.7-0.80.8-1.1-1.20.9-1.71.3-1.2-0.2-0.40.3-0.9
Bone: tissue strength2.42.33.11.51.41.71.7-1.71.51.5-1.71.2-1.81.71.31.5-1.41.3
Bone: trabecular number1.01.55.30.1-0.91.51.4-1.4-0.5-0.7-0.9-1.4-0.40.12.32.0-1.8-0.6
Bone: trabecular spacing0.81.02.90.81.2-0.6-0.50.51.01.10.41.7-0.40.7-1.5-1.21.20.9
Bone: trabecular thickness0.70.92.6-0.1-1.10.90.8-0.8-0.8-1.1-0.2-1.50.2-0.41.61.3-1.0-0.8
Bone: trabecular tissue density5.98.310.7-3.1-2.7-3.2-3.33.3-2.9-2.92.9-2.13.2-3.1-2.3-2.72.5-2.7
Breakpoint value in progressive ratio session2.32.63.5-1.4-1.6-1.7-1.71.7-1.6-1.71.9-1.31.8-1.7-1.3-1.51.5-1.5
Distance traveled before self-admin1.41.52.9-0.8-0.5-1.5-1.51.5-0.6-0.61.5-0.41.2-1.2-1.7-1.71.5-0.4
Distance traveled after self-admin0.30.30.5-0.5-0.3-0.7-0.70.7-0.4-0.40.7-0.70.7-0.6-0.7-0.60.6-0.2
Delta time in closed arm before/after self-admin0.60.50.9-0.7-0.5-0.8-0.80.8-0.5-0.60.9-0.81.0-1.0-0.7-0.70.7-0.1
Delta time in open arm before/after self-admin0.60.62.40.80.8-0.4-0.20.20.70.80.31.6-0.50.8-1.1-0.90.80.3
Diff in mean of infusions in LGA sessions0.20.20.8-0.0-0.2-0.5-0.50.5-0.2-0.30.9-0.50.5-0.4-0.6-0.60.8-0.0
Extinction: sum of active levers before priming0.70.82.0-0.3-0.1-1.1-1.11.1-0.3-0.21.10.30.6-0.3-1.4-1.41.3-0.3
Active lever presses in extinction session 60.00.00.1-0.0-0.2-0.0-0.00.0-0.2-0.20.2-0.30.1-0.20.10.00.2-0.2
Delta distance traveled before/after self-admin0.40.51.00.40.30.90.8-0.80.40.4-0.9-0.1-0.60.70.91.0-0.90.5
Delta ambulatory time before/after self-admin0.30.30.70.60.60.60.6-0.60.60.6-0.60.4-0.60.80.40.5-0.40.6
Time in closed arm before self-admin0.91.02.60.30.11.31.2-1.20.30.2-1.1-0.8-0.60.21.61.6-1.30.4
Time in closed arm after self-admin0.20.21.8-0.20.10.20.1-0.10.1-0.00.2-1.30.5-0.70.20.3-0.00.8
Time in open arm before self-admin0.40.40.7-0.8-0.6-0.6-0.70.7-0.7-0.60.5-0.70.8-0.7-0.3-0.40.2-0.4
Time in open arm after self-admin0.10.10.40.0-0.2-0.1-0.00.0-0.2-0.1-0.10.6-0.20.40.0-0.10.0-0.6
Sum of active levers in priming session hrs 5-60.40.41.1-0.3-0.5-0.7-0.60.6-0.6-0.50.60.60.2-0.1-0.6-0.80.9-1.1
Time to tail flick, vehicle, before self-admin1.81.82.9-1.5-1.1-1.7-1.71.7-1.3-1.11.1-0.11.3-1.3-1.3-1.51.4-1.4
Time to tail flick, vehicle, after self-admin0.70.81.5-0.7-0.4-1.1-1.11.1-0.5-0.51.0-0.40.9-0.9-1.1-1.11.2-0.4
Time to tail flick, test, before self-admin0.40.41.3-0.3-0.40.60.6-0.6-0.3-0.3-0.7-0.8-0.1-0.11.11.0-0.8-0.3
Time to tail flick, test, after self-admin0.20.21.1-0.6-0.7-0.3-0.30.3-0.7-0.70.0-0.10.2-0.30.2-0.10.2-1.1
Delta time to tail flick, vehicle, before/after SA0.30.30.90.90.90.30.3-0.30.80.8-0.00.4-0.50.5-0.3-0.00.31.0
Delta time to tail flick, test, before/after SA0.10.10.60.40.2-0.2-0.10.10.20.20.20.8-0.20.3-0.5-0.50.5-0.1
Ambulatory time before self-admin2.62.75.0-1.0-0.8-2.0-2.02.0-1.0-1.02.2-0.91.8-1.6-2.1-2.12.1-0.7
Ambulatory time after self-admin0.60.71.2-0.5-0.4-0.9-1.01.0-0.5-0.51.1-0.50.9-0.7-1.0-1.01.1-0.4
Total heroin consumption2.83.49.3-0.4-0.1-2.3-2.22.2-0.4-0.32.50.41.4-1.0-3.1-2.92.9-0.1
Area under the delay curve3.53.75.8-1.9-1.5-2.4-2.42.4-1.7-1.62.0-0.52.0-1.7-2.0-2.31.9-1.8
Delay disc. indifference point, 0s delay3.03.28.0-2.4-2.4-1.8-1.71.7-2.4-2.30.9-0.71.6-1.7-0.4-1.10.7-2.8
Delay disc. indifference point, 16s delay1.11.11.8-1.0-0.7-1.3-1.31.3-0.8-0.81.1-0.31.1-0.9-1.2-1.31.0-0.9
Delay disc. indifference point, 2s delay4.75.39.2-1.7-1.5-2.9-2.82.8-1.8-1.72.7-0.02.1-1.7-2.8-3.02.7-2.1
Delay disc. indifference point, 24s delay0.60.61.2-0.7-0.3-1.1-1.11.1-0.5-0.40.80.20.8-0.6-1.1-1.10.8-0.4
Delay disc. indifference point, 4s delay2.42.54.4-1.2-1.1-2.0-2.02.0-1.3-1.21.90.11.5-1.1-1.9-2.11.8-1.4
Delay disc. indifference point, 8s delay1.41.52.4-1.0-0.6-1.5-1.51.5-0.8-0.81.5-0.31.3-1.1-1.6-1.61.4-0.7
Delay discount exponential model param3.84.06.51.81.42.52.5-2.51.61.5-2.30.4-2.11.72.32.5-2.11.7
Delay discount hyperbolic model param3.63.86.21.71.32.52.4-2.41.61.5-2.20.3-2.01.62.32.4-2.01.7
Fecal boli incidents, locomotor time 10.50.53.0-0.7-0.7-0.2-0.30.3-0.7-0.80.5-1.70.9-1.00.20.1-0.4-0.4
Change in fecal boli incidents, locomotor task0.50.51.80.50.40.50.6-0.60.40.6-1.01.4-1.00.90.50.5-0.50.2
Time >=10cm from walls, locomotor time 11.41.43.5-0.5-0.5-1.6-1.51.5-0.7-0.61.40.50.8-0.5-1.7-1.91.6-1.0
Bouts of movement, locomotor time 10.20.31.4-0.5-0.60.30.2-0.2-0.5-0.6-0.1-1.20.4-0.40.70.6-0.4-0.2
Total resting periods, locomotor time 10.30.31.4-0.6-0.70.1-0.00.0-0.6-0.70.1-1.20.6-0.50.50.4-0.2-0.3
Rest time, locomotor task time 10.20.20.7-0.4-0.70.00.0-0.0-0.6-0.60.0-0.80.3-0.30.50.3-0.2-0.6
Distance moved, locomotor task time 10.20.20.7-0.20.1-0.6-0.60.6-0.0-0.00.6-0.10.5-0.4-0.8-0.70.60.0
Vertical activity count, locomotor time 10.10.10.5-0.4-0.2-0.3-0.30.3-0.2-0.30.4-0.70.6-0.6-0.2-0.10.10.0
Time >=10cm from walls, locomotor time 21.31.43.5-1.2-1.7-1.0-1.01.0-1.6-1.61.0-0.71.0-1.1-0.3-0.80.4-1.9
Bouts of movement, locomotor time 20.20.21.2-0.2-0.60.10.1-0.1-0.4-0.60.3-1.10.5-0.40.40.30.1-0.2
Total resting periods, locomotor time 20.10.20.7-0.1-0.40.40.3-0.3-0.3-0.40.1-0.90.2-0.20.60.5-0.0-0.1
Rest time, locomotor task time 20.10.10.70.30.2-0.3-0.20.20.10.10.40.30.00.1-0.5-0.50.90.1
Distance moved, locomotor task time 20.30.41.5-0.10.20.60.6-0.60.20.3-0.9-0.1-0.40.30.80.9-1.20.2
Vertical activity count, locomotor time 20.91.03.8-0.3-0.21.11.0-1.0-0.0-0.1-1.1-1.1-0.20.01.71.7-2.00.3
Weight adjusted by age1.11.22.50.70.31.41.4-1.40.50.4-1.20.1-1.01.01.61.5-1.50.3
Seeking ratio, delayed vs. immediate footshock2.02.34.41.62.01.11.2-1.21.92.0-1.42.1-1.81.80.20.6-0.61.8
Locomotion in novel chamber0.10.10.80.10.40.30.2-0.20.40.30.1-0.90.2-0.20.10.3-0.10.9
Locomotion in novel chamber post-restriction0.70.85.2-0.9-0.9-0.1-0.30.3-0.8-1.00.7-2.31.2-1.30.30.3-0.2-0.2
Progressive ratio0.50.51.60.81.00.30.4-0.40.91.0-0.41.3-0.80.9-0.20.00.00.9
Food seeking constrained by brief footshock3.03.65.72.42.31.71.8-1.82.32.3-1.52.3-2.22.40.61.0-0.92.2
Seeking ratio, punishment vs. effort0.30.30.80.30.00.80.7-0.70.10.1-0.5-0.3-0.40.30.90.8-0.90.1
Run reversals in cocaine runway, females0.20.20.50.60.60.10.1-0.10.60.6-0.10.7-0.40.5-0.3-0.20.40.6
Run reversals in cocaine runway, males0.60.52.20.81.10.60.6-0.61.11.0-0.40.2-0.40.50.10.4-0.21.5
Latency to leave start box in cocaine runway0.30.30.7-0.9-0.7-0.5-0.50.5-0.7-0.60.0-0.20.4-0.6-0.1-0.3-0.0-0.9
Latency to leave start box in cocaine runway, F0.40.41.3-0.4-0.50.50.5-0.5-0.4-0.3-1.0-0.0-0.40.11.10.9-1.1-0.7
Latency to leave start box in cocaine runway, M1.21.13.2-0.30.1-1.2-1.31.3-0.1-0.11.6-0.31.1-0.9-1.8-1.51.50.3
Cd content in liver1.31.45.31.42.00.40.4-0.41.81.8-0.11.1-0.70.8-0.9-0.30.32.3
Co content in liver2.02.43.51.41.31.91.8-1.81.51.4-1.60.5-1.51.31.51.8-1.71.6
Cu content in liver0.40.51.31.11.00.50.6-0.61.00.9-0.10.5-0.60.7-0.10.10.11.1
Fe content in liver0.91.13.4-0.6-1.1-0.6-0.70.7-1.0-1.21.5-1.81.3-1.3-0.4-0.50.8-0.6
K content in liver0.10.10.1-0.1-0.3-0.2-0.20.2-0.2-0.30.3-0.20.2-0.2-0.2-0.20.3-0.3
Mg content in liver0.10.10.3-0.3-0.50.20.2-0.2-0.4-0.4-0.2-0.60.1-0.20.60.4-0.5-0.4
Mn content in liver0.50.61.00.70.90.60.7-0.70.91.0-1.01.0-1.00.80.40.5-0.50.8
Na content in liver0.50.50.9-0.8-0.9-0.7-0.70.7-0.9-0.90.6-0.70.8-0.8-0.2-0.40.4-0.9
Rb content in liver0.70.82.30.91.0-0.5-0.40.40.80.80.81.1-0.30.4-1.5-1.21.40.8
Se content in liver2.63.14.5-1.5-2.0-1.7-1.71.7-2.0-2.12.0-1.51.8-1.8-1.0-1.51.6-2.1
Sr content in liver3.02.74.31.21.12.02.0-2.01.31.3-2.10.9-1.71.61.92.0-2.01.1
Zn content in liver2.12.36.10.70.12.01.9-1.90.40.3-1.7-0.5-1.10.82.52.4-2.30.3