Hub : Genes

Rapgefl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000027871 0.14 0.08 4.6e-06 0.1 0.08 0.07 0.09 4.7e-06 4.4e-05 1.9e-04 1.7e-05
2 BLA intron excision ratio chr10:83797395:83798685 0.09 0.06 1.6e-03 0.04 0.04 0.03 0.03 2.8e-03 5.0e-03 1.5e-02 6.1e-03
3 BLA mRNA stability ENSRNOG00000027871 0.25 0.14 4.7e-08 0.14 0.11 0.12 0.13 5.5e-08 1.1e-06 6.8e-07 2.2e-07
4 Brain gene expression ENSRNOG00000027871 0.18 0.07 0.0e+00 0.21 0.24 0.23 0.23 1.3e-19 1.2e-21 1.4e-21 6.6e-21
5 Brain mRNA stability ENSRNOG00000027871 0.08 0.04 2.9e-08 0.07 0.08 0.08 0.09 2.0e-07 4.0e-08 8.2e-08 2.3e-08
6 IL gene expression ENSRNOG00000027871 0.31 0.15 7.5e-06 0.13 0.18 0.17 0.13 5.7e-04 4.0e-05 8.7e-05 4.4e-04
7 IL mRNA stability ENSRNOG00000027871 0.71 0.26 1.3e-05 0.14 0.15 0.16 0.15 3.8e-04 2.0e-04 1.0e-04 2.1e-04
8 NAcc mRNA stability ENSRNOG00000027871 0.12 0.07 3.4e-09 0.09 0.1 0.1 0.1 4.1e-07 7.1e-08 7.5e-08 4.1e-08
9 OFC gene expression ENSRNOG00000027871 0.29 0.17 5.4e-04 0.11 0.12 0.01 0.04 1.4e-03 1.1e-03 1.5e-01 5.1e-02
10 OFC mRNA stability ENSRNOG00000027871 0.15 0.1 5.9e-03 0.06 0.07 0.04 0.06 1.8e-02 9.0e-03 3.6e-02 1.2e-02
11 PL gene expression ENSRNOG00000027871 0.17 0.08 2.3e-13 0.12 0.15 0.14 0.13 9.5e-10 3.0e-11 1.2e-10 2.3e-10
12 PL mRNA stability ENSRNOG00000027871 0.12 0.06 5.4e-09 0.1 0.1 0.08 0.1 5.9e-08 2.9e-08 1.5e-06 5.9e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.75.67.7-2.4-2.7-2.1-2.5-2.5-2.8-1.2-2.2-2.1-2.7-2.1-2.6
BMI without tail0.10.20.4-0.3-0.5-0.0-0.5-0.4-0.5-0.3-0.7-0.4-0.5-0.4-0.6
Body weight4.017.022.5-4.7-4.6-4.2-4.2-4.3-4.7-2.5-3.6-3.7-4.5-3.7-4.2
Epididymis fat weight0.00.10.5-0.4-0.2-0.70.0-0.1-0.20.3-0.20.2-0.10.00.0
Glucose0.10.20.70.40.20.10.30.10.30.90.50.40.30.40.5
Heart weight3.55.06.3-1.8-2.2-2.3-2.4-2.3-2.4-1.7-2.3-2.1-2.4-2.3-2.5
Left kidney weight0.92.63.8-1.6-1.9-1.2-1.8-1.6-1.8-1.8-0.5-2.0-1.6-1.4-1.5
Right kidney weight0.10.20.4-0.5-0.6-0.5-0.4-0.4-0.6-0.20.6-0.4-0.40.1-0.2
Tail length0.20.61.2-0.7-0.7-1.0-0.7-0.7-0.8-1.1-0.6-0.9-0.7-0.7-0.7
Length with tail2.28.110.4-3.1-3.1-3.2-2.9-2.8-3.1-2.4-2.1-2.8-2.9-2.6-2.7
Length without tail2.55.58.4-2.9-2.7-2.8-2.3-2.5-2.8-1.3-1.5-2.1-2.5-1.9-2.2
Liver weight, left0.00.10.20.20.3-0.10.30.20.20.20.40.20.30.30.3
Liver weight, right0.81.44.51.10.90.91.01.00.90.82.10.71.11.41.3
Parametrial fat weight2.34.45.42.02.12.22.12.11.92.02.32.12.12.32.0
Retroperitoneal fat weight0.00.00.10.2-0.20.2-0.2-0.0-0.30.20.1-0.1-0.2-0.0-0.1
Intraocular pressure3.44.88.1-1.8-2.2-1.8-2.1-2.2-2.2-2.0-2.8-1.9-2.2-2.2-2.5
Extensor digitorum longus weight9.337.541.3-6.3-6.3-6.3-6.2-6.4-6.4-5.0-5.9-5.8-6.3-6.1-6.3
Soleus weight0.10.32.5-0.2-0.1-0.10.30.10.11.60.20.80.00.40.4
Tibialis anterior weight1.24.25.6-2.3-2.3-2.2-2.1-2.3-2.4-1.2-1.5-1.9-2.3-1.8-2.1
Tibia length1.23.44.9-2.0-2.1-2.1-1.8-2.0-2.2-0.7-1.3-1.6-2.2-1.5-1.9
Number of licking bursts0.40.51.60.30.50.30.70.60.61.30.51.00.50.70.8
Food consumed during 24 hour testing period0.60.81.0-1.0-0.6-0.7-0.9-1.0-1.0-0.5-1.0-0.8-1.0-0.9-0.9
Times rat made contact with spout1.01.11.71.11.31.31.01.21.01.20.31.21.00.90.8
Mean time between licks in bursts1.11.53.2-1.2-1.4-0.9-1.2-1.2-1.2-0.6-1.8-0.7-1.3-1.3-1.2
Mean num. licks in bursts0.10.10.40.50.50.70.10.20.2-0.4-0.2-0.10.2-0.0-0.2
Std. dev. time between licks in bursts0.00.00.20.1-0.3-0.10.00.1-0.10.4-0.10.3-0.10.00.1
Water consumed over 24 hours0.10.10.3-0.30.3-0.1-0.2-0.2-0.30.3-0.5-0.0-0.3-0.3-0.2
Indifference point 0 sec1.52.43.41.81.71.81.51.81.90.90.91.51.71.21.7
Indifference point AUC0.00.00.4-0.1-0.2-0.6-0.1-0.2-0.1-0.00.2-0.0-0.1-0.00.0
Indifference point function ln k0.10.10.3-0.2-0.30.2-0.3-0.1-0.1-0.5-0.2-0.5-0.1-0.4-0.2
Indifference point function log k0.10.10.3-0.2-0.30.2-0.3-0.1-0.1-0.5-0.2-0.5-0.1-0.4-0.2
Delay discounting total patch changes 0 sec1.11.72.51.51.41.51.31.51.60.70.61.31.50.91.4
Delay discounting total patch changes 12 sec6.18.19.62.73.02.42.92.93.02.82.43.13.02.83.1
Delay discounting total patch changes 18 sec0.50.71.00.80.80.60.80.91.00.70.71.00.90.71.0
Delay discounting total patch changes 24 sec1.62.02.91.31.50.71.41.41.51.31.61.41.51.41.7
Delay discounting total patch changes 6 sec2.13.24.21.92.02.01.72.11.91.41.41.81.91.61.8
Delay discounting time to switch 0 sec0.10.20.30.30.30.50.50.50.40.50.30.50.50.50.5
Delay discounting water rate 0 sec0.00.10.20.40.40.40.20.30.2-0.10.20.10.20.10.2
Delay discounting water rate 12 sec0.10.10.6-0.7-0.2-0.8-0.1-0.3-0.2-0.30.2-0.3-0.1-0.2-0.0
Delay discounting water rate 18 sec0.91.22.30.60.90.71.11.10.91.51.51.11.01.21.2
Delay discounting water rate 24 sec0.81.11.61.11.11.30.91.20.91.00.91.01.00.90.9
Delay discounting water rate 6 sec1.82.63.21.51.71.61.61.81.61.21.81.51.71.71.7
Locomotor activity1.01.62.80.61.20.81.31.31.11.71.31.41.11.41.4
Locomotor testing distance2.43.94.61.82.12.02.12.12.11.61.82.02.02.02.1
Locomotor testing rearing5.89.111.43.43.23.32.93.23.31.92.82.73.22.83.2
Light reinforcement 13.36.17.82.52.52.52.42.82.52.02.42.42.52.42.5
Light reinforcement 20.91.22.31.41.00.91.01.20.91.51.01.20.91.21.0
Reaction time number correct0.50.71.8-0.9-0.7-1.3-0.8-1.0-1.0-0.4-0.6-0.7-1.0-0.8-0.8
Reaction time mean minus median0.50.62.0-0.5-0.7-0.7-0.7-0.6-0.6-0.6-1.4-0.5-0.7-0.9-0.8
Reaction time mean minus median AUC0.10.10.70.1-0.2-0.1-0.2-0.1-0.1-0.2-0.8-0.1-0.2-0.4-0.4
Reaction time num false alarms0.81.12.21.00.90.81.00.90.91.50.81.30.91.11.1
Reaction time num false alarms AUC0.70.92.30.80.80.71.00.80.81.50.61.30.80.91.0
Reaction time trials correct on left0.50.71.8-0.9-0.7-1.3-0.8-1.0-1.0-0.4-0.6-0.7-1.0-0.8-0.8
Reaction time trials on left0.50.71.7-0.9-0.7-1.3-0.7-0.9-0.9-0.4-0.6-0.7-0.9-0.8-0.8
Reaction time mean0.10.10.30.30.60.50.30.40.4-0.40.30.00.40.20.2
Reaction time mean AUC0.10.10.30.40.60.50.30.40.4-0.40.4-0.00.40.20.2
Median of all reaction times0.71.01.71.01.31.31.01.01.10.21.10.61.10.90.9
Reaction time omissions1.21.62.11.21.41.41.31.41.31.11.01.21.31.31.2
Reaction time false alarm rate1.11.52.31.11.01.31.21.21.21.50.91.51.21.21.3
Reaction time premature initiation rate0.70.94.10.10.90.30.90.80.70.42.00.40.91.21.0
Reaction time premature initiations0.20.21.6-0.60.3-0.60.2-0.0-0.1-0.11.3-0.20.00.40.2
Std. dev. reaction times0.00.10.4-0.0-0.1-0.1-0.1-0.1-0.1-0.3-0.6-0.1-0.1-0.2-0.3
Reaction time trials completed0.50.71.7-0.9-0.7-1.3-0.7-0.9-0.9-0.4-0.6-0.7-0.9-0.8-0.8
Reaction time trials AUC0.50.71.7-0.9-0.7-1.3-0.7-0.9-0.9-0.5-0.7-0.7-0.9-0.8-0.8
Social response proportion0.30.40.6-0.6-0.8-0.7-0.7-0.5-0.7-0.2-0.4-0.6-0.7-0.6-0.6
Social responses0.10.20.80.30.10.40.30.50.20.90.10.50.20.40.4
Social time0.10.10.60.00.1-0.00.1-0.0-0.10.8-0.50.5-0.10.2-0.1
Conditioned locomotion0.10.20.40.50.40.20.30.30.40.10.60.20.50.40.5
Cocaine response after cond. corrected1.11.22.70.90.80.81.10.91.01.61.21.20.91.31.2
Cocaine response after cond. not corrected1.51.63.41.11.00.71.31.01.21.81.41.41.11.51.4
Cocaine response before conditioning0.10.10.20.40.40.10.20.20.30.20.30.20.30.20.3
Saline control response0.10.10.4-0.5-0.5-0.6-0.2-0.5-0.30.4-0.0-0.1-0.4-0.1-0.1
Condit. Reinf. active minus inactive responses1.31.62.11.21.21.11.41.21.31.40.91.41.31.31.3
Condit. Reinf. active-inactive response ratio1.21.31.91.01.11.11.21.11.11.40.81.41.11.21.1
Condit. Reinf. active responses2.23.13.91.71.61.71.91.81.71.91.42.01.81.81.8
Condit. Reinf. inactive responses2.32.83.21.71.61.61.81.71.71.61.61.81.71.81.8
Condit. Reinf. lever presses0.10.20.30.30.30.40.40.40.50.20.50.30.50.40.6
Condit. Reinf. lever reinforcers received2.23.13.51.71.61.61.81.81.81.71.51.91.81.81.8
Pavlov. Cond. lever latency0.40.60.7-0.7-0.8-0.8-0.8-0.8-0.8-0.8-0.5-0.8-0.8-0.7-0.8
Pavlov. Cond. magazine entry latency0.10.10.3-0.20.2-0.5-0.1-0.3-0.2-0.1-0.3-0.1-0.3-0.2-0.2
Pavlov. Cond. change in total contacts0.60.81.21.11.01.00.90.91.10.60.40.91.00.70.9
Pavlov. Cond. index score0.20.30.40.60.60.50.60.50.50.70.20.60.50.50.5
Pavlov. Cond. latency score0.10.10.30.40.50.30.40.30.40.5-0.00.50.30.30.3
Pavlov. Cond. lever contacts1.01.41.81.11.11.11.21.21.21.40.91.31.11.21.2
Pavlov. Cond. magazine entry number0.00.00.2-0.3-0.40.0-0.2-0.2-0.1-0.2-0.2-0.2-0.1-0.2-0.2
Pavlov. Cond. intertrial magazine entries1.92.43.3-1.6-1.6-1.5-1.6-1.6-1.4-1.8-1.5-1.7-1.4-1.7-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.50.50.30.40.40.30.50.10.50.30.30.3
Pavlov. Cond. response bias1.31.82.01.41.41.21.41.41.31.41.21.41.31.41.4
Conditioned reinforcement - actives0.50.50.90.60.80.20.90.71.00.60.00.80.80.60.9
Conditioned reinforcement - inactives1.51.73.51.61.91.71.31.41.40.60.51.21.41.01.1
Conditioned locomotion0.50.61.20.40.7-0.10.90.71.01.0-0.11.10.80.61.0
Intermittent access intake day 1-15 change0.50.51.10.61.00.70.70.90.70.31.00.40.70.80.7
Intermittent access intake escalation0.60.61.40.61.00.70.80.90.70.41.20.40.80.90.7
Intermittent access intake escalation 20.00.00.1-0.00.40.30.20.30.10.20.30.10.10.30.1
Intermitt. access day 1 inactive lever presses3.03.25.52.01.72.31.61.91.51.32.31.31.71.91.6
Intermitt. access day 15 inactive lever presses4.34.86.32.52.42.52.22.52.31.31.91.82.32.12.1
Intermitt. access escalation Index1.71.53.0-1.7-1.5-1.1-1.3-1.4-1.4-0.5-0.4-1.2-1.3-1.0-1.0
Intermittent access day 1 total infusions0.20.20.40.40.70.10.50.30.50.30.30.50.50.50.5
Intermittent access day 15 total infusions0.60.71.70.71.20.70.80.80.80.31.30.40.80.90.8
Intermittent access terminal intake (last 3 days)0.80.81.60.81.20.90.90.90.90.51.10.70.91.00.8
Intermittent access total infusions0.20.20.70.30.80.30.50.30.40.00.80.20.50.50.4
Intermittent access day 1 locomotion0.20.20.40.60.50.10.40.40.50.3-0.30.60.40.20.4
Intermittent access day 15 total locomotion0.30.30.60.80.70.20.60.50.70.5-0.60.80.50.30.4
Intermittent access total locomotion0.50.61.01.01.00.50.90.81.00.30.10.80.90.60.7
Intermittent access standard deviation1.92.03.91.22.01.51.41.61.40.51.61.01.51.41.3
Cocaine induced anxiety1.11.32.3-1.5-1.5-0.9-1.1-1.3-1.5-0.3-0.5-1.0-1.3-0.7-1.1
Post-drug Anxiety0.10.10.2-0.3-0.5-0.3-0.3-0.5-0.5-0.20.3-0.4-0.4-0.1-0.3
Baseline Anxiety0.70.71.51.21.10.70.91.01.20.10.40.71.00.50.8
Lifetime Intake0.30.41.10.50.90.40.60.50.50.11.00.30.60.70.5
Incentive Sensitization - Responses1.21.22.21.11.51.21.21.11.30.7-0.21.31.20.81.0
Incentive Sensitization - Breakpoint1.21.22.11.11.41.21.21.01.30.7-0.11.31.20.81.0
Progressive ratio test 1 active lever presses0.50.50.60.80.70.70.70.70.80.40.80.50.70.60.7
Progressive ratio test 1 breakpoint0.40.40.60.70.60.70.60.70.70.30.80.50.60.60.7
Progressive ratio test 1 inactive lever presses1.81.93.21.51.51.81.21.51.30.71.61.01.41.31.3
Progressive ratio test 2 active lever presses1.11.12.01.11.41.11.21.11.30.50.61.01.20.91.1
Progressive ratio test 2 breakpoint0.70.81.50.91.20.91.00.91.10.40.50.81.00.80.9
Progressive ratio test 2 inactive lever presses0.50.61.40.91.20.70.80.80.80.30.40.70.80.70.6
Total sessions with >9 infusions0.60.71.20.90.91.00.60.90.80.41.10.40.80.60.8
Short access day 1 total inactive lever presses2.12.44.31.82.11.31.51.71.51.01.51.31.61.51.4
Short access day 10 total inactive lever presses0.00.00.2-0.30.2-0.0-0.10.1-0.30.00.5-0.3-0.10.1-0.2
Short access day 1 total infusions0.90.92.61.11.11.10.70.90.80.21.60.40.91.00.8
Short access day 10 total infusions0.50.50.80.80.90.50.80.70.70.60.80.70.70.80.8
Short access total infusions0.40.52.00.60.90.50.50.60.50.01.40.10.60.70.6
Short access day 1 locomotion4.14.46.02.22.32.52.02.32.11.71.91.92.21.92.1
Short access day 10 total locomotion1.31.52.51.61.11.11.31.21.41.10.01.51.31.01.2
Short access total locomotion0.40.41.11.10.90.70.50.80.70.30.10.50.70.30.6
Compulsive drug intake1.01.01.9-0.6-0.6-0.5-1.0-0.7-0.8-1.4-1.2-1.2-0.9-1.3-1.1
One hour access (0.3 mA shock)0.00.00.1-0.10.1-0.30.0-0.00.1-0.3-0.1-0.10.0-0.10.0
One hour access (shock baseline)0.50.61.00.60.80.40.80.60.70.71.00.80.81.00.9
Number of responses in last shaping day0.40.40.90.90.80.80.40.80.5-0.20.80.10.60.50.4
Context. condit. distance diff. score2.12.54.1-1.3-1.3-1.3-1.7-1.6-1.5-2.0-1.1-2.0-1.5-1.8-1.6
Locomotion velocity, session 10.20.30.6-0.6-0.7-0.8-0.5-0.5-0.60.1-0.3-0.3-0.5-0.3-0.4
Locomotion distance, session 11.41.93.3-1.6-1.6-1.8-1.3-1.3-1.6-0.2-1.3-1.0-1.5-1.1-1.3
Locomotion velocity, session 20.10.10.2-0.4-0.4-0.5-0.4-0.3-0.4-0.30.1-0.4-0.3-0.2-0.3
Locomotion distance, session 20.10.10.5-0.4-0.3-0.50.10.1-0.20.70.10.3-0.10.30.1
Locomotion velocity, session 30.00.00.10.10.30.10.10.30.2-0.30.3-0.00.20.10.2
Locomotion distance, session 30.10.20.3-0.3-0.5-0.6-0.4-0.2-0.4-0.3-0.5-0.3-0.4-0.4-0.3
Stereotopy head waving bouts, day 32.12.53.51.71.71.91.51.61.70.91.91.21.71.51.6
Stereotopy head waving duration, day 30.10.10.70.30.30.60.20.20.30.10.80.00.30.30.3
Locomotion velocity, session 70.80.92.1-1.0-1.2-1.4-0.8-0.9-1.0-0.2-1.0-0.5-1.0-0.8-0.8
Locomotion distance, session 70.50.61.6-0.6-0.8-1.1-0.6-0.8-0.7-0.3-1.3-0.3-0.7-0.8-0.7
Stereotopy head waving bouts, day 70.60.71.40.70.60.80.80.90.80.91.20.70.80.90.9
Stereotopy head waving duration, day 70.40.51.60.50.40.60.60.80.60.61.20.50.70.80.7
Locomotion velocity, session 88.19.710.7-3.2-3.1-3.1-3.2-3.3-3.3-2.8-2.7-3.2-3.2-3.0-3.3
Locomotion distance, session 81.11.62.2-1.4-1.4-1.5-1.3-1.3-1.4-0.8-1.0-1.2-1.4-1.2-1.2
Degree of sensitization distance1.51.52.2-1.2-1.1-1.2-1.2-1.4-1.2-0.9-1.5-1.0-1.2-1.3-1.3
Degree of sensitization stereotypy1.01.11.60.90.80.91.01.11.01.21.21.01.01.11.1
Condit. Reinf. active minus inactive responses0.60.71.20.91.10.70.81.11.00.10.90.51.00.80.8
Condit. Reinf. active-inactive response ratio0.70.81.20.91.10.80.81.01.1-0.01.00.51.10.70.9
Condit. Reinf. active responses0.60.81.20.91.10.70.91.11.00.20.90.61.00.80.9
Condit. Reinf. inactive responses0.10.20.30.30.40.10.40.40.40.50.40.50.30.50.3
Incentive salience index mean1.72.12.91.51.61.41.51.71.60.91.21.31.61.41.5
Condit. Reinf. lever presses1.01.41.81.21.11.01.21.31.21.30.71.31.21.11.2
Time in familiar zone, hab. session 10.90.93.40.70.50.80.80.60.51.80.91.00.61.10.8
Time in novel zone, hab. session 10.30.20.80.70.60.50.20.60.6-0.9-0.3-0.00.4-0.10.1
Total zone transitions, hab. session 11.82.63.1-1.6-1.6-1.5-1.7-1.6-1.7-1.4-1.5-1.6-1.7-1.6-1.8
Total locomotion distance, hab. session 10.00.00.2-0.00.2-0.1-0.2-0.1-0.2-0.20.0-0.4-0.1-0.2-0.2
Locomotion velocity, hab. session 10.30.40.6-0.7-0.4-0.6-0.6-0.6-0.7-0.6-0.1-0.8-0.6-0.5-0.6
Time in familiar zone, hab. session 20.80.81.80.90.80.90.80.80.70.81.30.70.81.10.8
Time in novel zone, hab. session 20.10.10.20.40.30.30.30.50.50.1-0.20.40.40.10.3
Total zone transitions, hab. session 21.01.32.1-1.1-1.2-1.3-1.1-1.1-1.2-0.6-1.4-0.9-1.2-1.1-1.2
Total locomotion distance, hab. session 20.20.30.6-0.5-0.4-0.6-0.4-0.4-0.60.1-0.8-0.3-0.6-0.4-0.6
Locomotion velocity, hab. session 20.40.50.8-0.7-0.6-0.9-0.6-0.7-0.8-0.1-0.9-0.5-0.8-0.6-0.8
Novel to familiar place preference ratio1.11.22.1-1.0-1.2-1.1-1.1-1.1-1.0-1.5-0.4-1.3-1.0-1.0-1.0
Novelty place preference1.11.12.3-0.9-1.1-1.0-1.1-1.1-0.9-1.5-0.5-1.3-0.9-1.0-0.9
Time in novel zone, NPP test0.40.41.2-0.5-0.7-0.6-0.7-0.6-0.5-1.1-0.1-0.9-0.5-0.6-0.5
Total zone transitions, NPP test0.40.61.3-0.8-0.9-0.8-0.6-0.8-0.80.4-1.1-0.2-0.8-0.6-0.7
Total locomotion distance, NPP test0.10.10.9-0.00.0-0.00.1-0.0-0.10.9-0.40.4-0.10.0-0.0
Locomotion velocity, NPP test0.30.41.0-0.6-0.5-0.6-0.6-0.6-0.70.3-1.0-0.2-0.7-0.6-0.7
Pavlov. Cond. lever latency3.54.46.3-2.0-1.9-2.0-2.2-2.2-2.0-2.5-1.7-2.4-2.0-2.2-2.1
Pavlov. Cond. magazine entry latency10.613.614.93.73.63.73.83.93.73.43.43.73.73.83.7
Pavlov. Cond. change in total contacts8.28.711.43.33.13.42.93.23.12.02.82.63.12.82.9
Pavlov. Cond. index score8.711.112.33.33.23.33.43.53.43.42.83.53.33.43.3
Pavlov. Cond. latency score6.88.69.92.92.82.93.03.12.93.22.43.22.93.02.9
Pavlov. Cond. lever contacts2.93.45.31.71.61.81.91.91.72.31.22.21.71.91.8
Pavlov. Cond. magazine entry number12.315.317.3-4.2-4.0-4.2-4.0-4.1-4.0-3.5-3.5-3.8-4.0-3.9-3.9
Pavlov. Cond. intertrial magazine entries1.82.23.1-1.5-1.4-1.6-1.5-1.4-1.4-1.8-1.3-1.6-1.4-1.5-1.5
Pavlov. Cond. lever-magazine prob. diff.9.411.813.23.53.43.53.53.63.53.42.83.63.53.43.4
Pavlov. Cond. response bias9.411.512.93.53.43.53.43.63.53.13.03.33.53.43.4
Bone: apparent density2.74.65.71.92.12.12.12.22.12.12.42.02.12.22.2
Bone surface0.20.31.20.30.20.30.40.50.21.10.80.60.30.70.6
Bone volume0.50.92.50.60.70.70.80.80.61.61.11.10.71.10.9
Bone: connectivity density3.75.87.42.22.32.22.42.62.42.12.72.22.52.52.6
Bone: cortical apparent density4.66.09.73.13.02.72.42.62.81.21.92.12.72.12.3
Bone: cortical area0.10.10.20.30.30.20.30.30.30.40.30.30.30.30.4
Bone: cortical porosity0.30.41.10.20.30.40.60.50.41.10.80.60.40.70.6
Bone: cortical porosity0.20.31.20.10.20.10.50.30.31.10.70.50.30.70.5
Bone: cortical thickness0.81.32.01.21.30.91.11.21.30.61.40.81.21.01.3
Bone: cortical thickness5.05.89.72.52.62.22.42.42.51.63.11.82.62.42.6
Bone: cortical tissue density4.76.19.83.12.92.72.52.62.81.21.92.12.72.12.3
Bone: elastic displacement0.00.10.50.00.1-0.2-0.1-0.0-0.0-0.0-0.70.0-0.1-0.3-0.2
Bone: elastic work0.10.20.50.30.40.10.40.40.30.60.70.40.40.50.4
Bone: endosteal estimation1.32.84.8-1.9-2.2-1.6-1.7-1.9-2.0-0.4-1.6-1.1-1.9-1.4-1.7
Bone: endosteal perimeter0.91.93.0-1.5-1.7-1.1-1.4-1.5-1.6-0.7-1.7-0.9-1.5-1.3-1.4
Bone: final force1.01.63.60.80.90.91.21.11.11.91.61.41.11.51.4
Bone: final moment0.71.23.00.70.70.81.00.90.91.71.31.20.91.31.2
Bone: marrow area1.22.64.4-1.9-2.1-1.5-1.6-1.8-2.0-0.4-1.6-1.1-1.9-1.4-1.6
Bone: maximum diameter0.10.10.30.20.10.50.40.40.30.50.30.50.30.40.4
Bone: maximum force0.10.10.7-0.1-0.20.00.10.0-0.00.90.50.40.00.30.3
Bone: maximum moment0.00.10.4-0.3-0.3-0.1-0.1-0.2-0.20.70.20.2-0.20.10.1
Bone: minimum diameter0.30.51.1-0.9-1.1-0.7-0.7-0.8-0.9-0.2-0.5-0.6-0.8-0.6-0.6
Bone: periosteal estimation0.10.20.5-0.6-0.7-0.3-0.4-0.5-0.60.4-0.3-0.1-0.5-0.2-0.3
Bone: periosteal perimeter0.40.61.1-0.9-1.0-0.6-0.7-0.9-1.00.0-0.9-0.4-0.9-0.7-0.7
Bone: post-yield work1.31.82.6-1.5-1.6-1.2-1.4-1.4-1.4-0.7-1.3-1.2-1.4-1.3-1.2
Bone: stiffness0.10.20.8-0.1-0.00.20.2-0.00.10.70.90.20.10.40.4
Bone: tissue strength1.11.12.1-1.1-1.1-1.0-1.1-1.0-1.0-0.6-1.5-0.8-1.1-1.2-1.0
Bone: trabecular number6.29.611.12.93.02.93.13.23.03.03.33.03.13.33.2
Bone: trabecular spacing1.31.72.2-1.3-1.3-1.4-1.2-1.5-1.5-0.5-1.5-0.9-1.5-1.2-1.4
Bone: trabecular thickness0.20.20.30.40.40.50.40.50.40.60.20.50.40.40.4
Bone: trabecular tissue density0.20.31.3-0.1-0.2-0.3-0.5-0.4-0.1-1.1-0.6-0.6-0.2-0.7-0.4
Breakpoint value in progressive ratio session0.20.21.0-0.30.4-0.80.40.30.20.11.00.20.30.40.4
Distance traveled before self-admin0.00.00.20.10.00.10.1-0.2-0.1-0.10.50.10.00.30.0
Distance traveled after self-admin1.11.22.0-1.4-1.1-0.5-1.1-1.2-1.3-1.0-0.8-1.1-1.2-0.9-1.3
Delta time in closed arm before/after self-admin3.63.55.1-1.9-1.8-2.3-2.0-1.8-2.1-1.4-1.2-1.9-2.0-1.7-2.0
Delta time in open arm before/after self-admin0.00.00.1-0.00.10.3-0.1-0.1-0.1-0.40.3-0.3-0.1-0.1-0.2
Diff in mean of infusions in LGA sessions0.10.11.0-0.50.2-1.00.20.10.00.00.20.00.10.20.2
Extinction: sum of active levers before priming1.31.32.3-1.5-1.4-1.3-1.2-1.2-1.3-0.3-0.6-0.9-1.3-1.0-1.1
Active lever presses in extinction session 63.23.15.41.31.11.01.81.51.42.22.31.91.62.32.0
Delta distance traveled before/after self-admin1.71.82.6-1.6-1.3-1.2-1.4-1.2-1.4-1.2-1.3-1.4-1.4-1.3-1.4
Delta ambulatory time before/after self-admin1.11.22.6-1.6-1.3-0.7-1.1-1.0-1.1-0.6-1.1-1.0-1.1-1.0-1.1
Time in closed arm before self-admin1.01.14.41.40.92.10.81.01.10.60.40.81.00.61.0
Time in closed arm after self-admin0.70.81.4-0.6-0.8-0.2-1.1-0.8-0.8-1.2-0.3-1.2-0.8-1.1-0.9
Time in open arm before self-admin1.71.86.2-1.9-1.1-2.5-1.1-1.5-1.3-0.7-0.9-1.1-1.2-1.0-1.0
Time in open arm after self-admin0.50.51.1-0.9-0.4-1.0-0.6-0.9-0.7-0.6-0.6-0.6-0.7-0.6-0.8
Sum of active levers in priming session hrs 5-60.70.71.60.50.60.20.80.90.71.11.30.70.71.00.9
Time to tail flick, vehicle, before self-admin0.10.10.80.20.30.40.00.00.10.2-0.90.3-0.1-0.3-0.2
Time to tail flick, vehicle, after self-admin0.10.10.30.10.0-0.10.30.40.30.4-0.50.50.20.30.2
Time to tail flick, test, before self-admin1.51.52.7-1.7-1.2-1.2-1.1-1.3-1.2-0.8-1.3-1.1-1.2-1.2-1.2
Time to tail flick, test, after self-admin0.20.20.60.70.40.30.30.30.20.6-0.60.70.20.20.0
Delta time to tail flick, vehicle, before/after SA0.50.51.30.20.30.30.80.80.61.20.41.00.71.00.8
Delta time to tail flick, test, before/after SA2.32.15.32.31.61.31.41.41.41.20.51.61.41.31.2
Ambulatory time before self-admin0.00.00.20.1-0.00.0-0.1-0.3-0.2-0.4-0.0-0.2-0.2-0.1-0.3
Ambulatory time after self-admin1.71.93.2-1.8-1.5-0.5-1.4-1.4-1.7-1.0-1.2-1.3-1.6-1.1-1.6
Total heroin consumption3.03.66.01.11.90.92.11.91.82.51.82.31.92.12.0
Area under the delay curve0.20.20.30.40.40.60.40.40.50.20.40.20.40.40.5
Delay disc. indifference point, 0s delay1.11.11.51.01.11.01.10.91.20.91.11.01.11.11.2
Delay disc. indifference point, 16s delay0.20.21.00.80.30.70.10.10.3-0.51.0-0.40.30.20.3
Delay disc. indifference point, 2s delay1.11.32.01.01.00.71.21.11.21.40.71.31.11.21.3
Delay disc. indifference point, 24s delay0.10.10.3-0.1-0.30.1-0.4-0.4-0.2-0.5-0.5-0.4-0.3-0.5-0.3
Delay disc. indifference point, 4s delay0.80.92.40.70.90.61.00.80.90.61.50.70.91.11.1
Delay disc. indifference point, 8s delay0.10.10.40.00.20.60.30.30.40.4-0.10.30.30.20.4
Delay discount exponential model param0.10.10.2-0.3-0.2-0.4-0.2-0.2-0.30.0-0.30.0-0.2-0.2-0.3
Delay discount hyperbolic model param0.10.10.2-0.4-0.3-0.5-0.3-0.4-0.4-0.2-0.4-0.2-0.4-0.4-0.4
Fecal boli incidents, locomotor time 10.40.51.5-0.5-0.7-0.6-0.6-0.6-0.6-0.4-1.2-0.3-0.7-0.7-0.8
Change in fecal boli incidents, locomotor task0.10.00.2-0.5-0.0-0.4-0.1-0.3-0.00.1-0.1-0.1-0.1-0.10.1
Time >=10cm from walls, locomotor time 10.10.10.30.60.2-0.30.20.10.4-0.2-0.00.10.3-0.00.3
Bouts of movement, locomotor time 10.30.30.6-0.8-0.7-0.2-0.6-0.4-0.6-0.50.0-0.5-0.6-0.3-0.5
Total resting periods, locomotor time 10.70.81.5-1.2-1.1-0.7-0.9-0.8-1.0-0.6-0.5-0.8-1.0-0.7-0.9
Rest time, locomotor task time 10.10.20.7-0.20.00.60.20.50.20.8-0.10.60.20.20.2
Distance moved, locomotor task time 10.10.10.70.80.3-0.40.1-0.10.1-0.30.4-0.20.10.20.1
Vertical activity count, locomotor time 10.30.32.1-0.1-0.1-1.5-0.3-0.6-0.3-0.4-0.4-0.5-0.4-0.3-0.3
Time >=10cm from walls, locomotor time 21.21.22.41.00.9-0.01.30.71.41.10.81.31.21.11.6
Bouts of movement, locomotor time 20.30.30.90.70.10.70.40.70.50.10.90.30.60.50.7
Total resting periods, locomotor time 20.20.20.70.5-0.00.50.20.50.3-0.10.80.10.40.30.5
Rest time, locomotor task time 20.80.92.1-1.4-1.1-1.1-0.9-0.9-1.0-0.6-0.8-0.7-0.9-0.8-0.9
Distance moved, locomotor task time 20.10.10.50.5-0.3-0.7-0.2-0.3-0.30.10.0-0.2-0.2-0.0-0.1
Vertical activity count, locomotor time 20.40.41.6-0.1-0.5-1.3-0.6-0.7-0.6-0.5-0.7-0.6-0.6-0.6-0.6
Weight adjusted by age0.20.21.4-0.8-0.6-1.2-0.0-0.4-0.30.20.5-0.0-0.20.20.0
Seeking ratio, delayed vs. immediate footshock0.20.21.20.70.5-0.10.10.10.3-1.10.1-0.50.2-0.1-0.0
Locomotion in novel chamber5.36.69.23.02.61.82.72.52.71.92.92.32.72.72.7
Locomotion in novel chamber post-restriction1.51.72.51.21.21.21.51.41.31.61.11.61.21.41.2
Progressive ratio0.30.30.50.60.2-0.20.60.60.50.60.60.70.50.70.7
Food seeking constrained by brief footshock0.50.61.10.40.51.00.70.80.61.00.40.80.70.80.8
Seeking ratio, punishment vs. effort0.10.10.4-0.3-0.00.6-0.2-0.2-0.1-0.1-0.5-0.2-0.2-0.3-0.2
Run reversals in cocaine runway, females3.43.35.5-1.9-1.3-1.9-1.9-1.9-1.8-2.2-1.0-2.3-1.8-1.8-1.7
Run reversals in cocaine runway, males0.30.30.80.90.80.80.60.40.60.10.10.40.50.50.4
Latency to leave start box in cocaine runway1.41.62.0-0.9-1.1-1.3-1.4-1.4-1.4-1.1-0.9-1.4-1.4-1.3-1.4
Latency to leave start box in cocaine runway, F1.41.52.2-1.1-1.1-1.3-1.3-1.5-1.4-1.1-0.5-1.4-1.3-1.1-1.3
Latency to leave start box in cocaine runway, M0.10.10.70.90.40.50.10.50.3-0.1-0.10.10.30.00.2
Cd content in liver0.10.10.40.50.40.60.30.40.30.10.40.10.30.30.2
Co content in liver0.91.12.1-0.8-0.7-0.8-1.0-0.9-1.0-1.5-1.0-1.2-1.0-1.0-1.3
Cu content in liver0.10.10.90.10.2-0.0-0.2-0.0-0.1-1.00.0-0.5-0.1-0.2-0.3
Fe content in liver0.60.71.1-1.0-1.0-1.1-0.9-1.0-1.1-0.4-0.3-0.8-1.0-0.6-0.8
K content in liver1.91.94.51.01.31.11.41.31.40.92.11.11.41.51.6
Mg content in liver0.91.02.50.81.11.00.90.91.1-0.31.60.31.10.91.1
Mn content in liver2.42.83.91.51.71.71.61.81.80.92.01.31.81.61.9
Na content in liver0.80.92.30.50.60.50.90.70.71.41.50.90.81.31.1
Rb content in liver1.21.52.41.41.41.51.21.31.40.61.01.11.31.11.2
Se content in liver5.56.78.42.72.82.82.62.72.71.52.92.12.82.62.6
Sr content in liver0.00.00.10.20.30.20.10.20.3-0.3-0.10.00.3-0.00.2
Zn content in liver3.13.54.91.92.12.21.92.01.91.31.51.81.91.81.7