Adamts3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000027463 0.16 0.08 3.2e-06 0.07 0.1 0.1 0.08 1.2e-04 7.8e-06 6.6e-06 3.4e-05
2 Brain gene expression ENSRNOG00000027463 0.21 0.08 1.6e-12 0.08 0.15 0.14 0.14 1.4e-07 1.7e-13 9.4e-13 6.8e-13
3 Brain mRNA stability ENSRNOG00000027463 0.1 0.05 2.1e-08 0.07 0.09 0.06 0.07 2.4e-07 3.0e-08 2.5e-06 2.7e-07
4 LHb gene expression ENSRNOG00000027463 0.27 0.15 3.7e-03 0.05 0.06 0.05 0.08 2.6e-02 1.2e-02 2.1e-02 6.5e-03
5 Liver gene expression ENSRNOG00000027463 0.04 0.03 2.5e-03 0 0.02 0.01 0.01 9.5e-02 1.3e-03 7.0e-03 1.3e-02
6 NAcc gene expression ENSRNOG00000027463 0.45 0.12 0.0e+00 0.32 0.35 0.33 0.35 3.3e-24 5.7e-27 3.6e-25 5.5e-27
7 NAcc mRNA stability ENSRNOG00000027463 0.04 0.03 8.7e-03 0.04 0.03 0.02 0.03 6.9e-04 5.2e-03 1.0e-02 5.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail1.75.311.8-1.40.7-3.20.53.42.9-2.2
BMI without tail0.20.40.7-0.8-0.3-0.8-0.30.70.6-0.6
Body weight0.21.02.9-1.3-1.7-0.2-0.4-0.4-1.50.5
Epididymis fat weight0.20.61.4-0.1-0.9-0.1-1.20.2-0.90.9
Glucose0.81.32.21.1-0.31.5-1.1-1.3-1.11.3
Heart weight0.10.20.50.20.50.60.3-0.70.0-0.4
Left kidney weight0.61.84.00.3-0.71.7-0.2-2.0-1.61.5
Right kidney weight0.82.45.30.2-1.01.9-0.3-2.3-2.21.5
Tail length1.65.013.8-0.7-2.61.7-1.0-2.7-3.71.5
Length with tail2.910.523.10.8-2.13.7-1.1-4.4-4.83.3
Length without tail1.53.26.71.2-0.42.2-0.7-1.9-2.22.6
Liver weight, left1.01.64.1-0.2-1.5-0.5-1.90.9-0.42.0
Liver weight, right0.40.72.10.3-0.7-0.1-1.20.6-0.21.4
Parametrial fat weight0.10.30.4-0.4-0.60.30.3-0.6-0.70.6
Retroperitoneal fat weight0.61.94.70.1-1.31.0-1.4-1.0-1.72.2
Intraocular pressure1.92.78.2-1.6-2.9-1.3-1.70.5-1.70.2
Extensor digitorum longus weight7.730.759.3-4.60.4-7.72.97.05.5-6.8
Soleus weight2.57.318.81.23.5-1.71.73.14.3-1.8
Tibialis anterior weight2.69.119.1-1.31.1-4.01.04.43.8-3.2
Tibia length2.05.514.71.21.13.42.1-3.8-2.01.2
Number of licking bursts1.21.44.3-1.4-2.1-0.9-0.80.2-1.2-0.7
Food consumed during 24 hour testing period0.20.20.8-0.10.2-0.50.10.70.90.2
Times rat made contact with spout1.01.12.4-0.7-0.2-1.50.21.51.0-1.2
Mean time between licks in bursts0.40.62.1-0.6-0.90.30.1-0.9-1.5-0.3
Mean num. licks in bursts0.91.13.31.11.80.30.80.51.60.4
Std. dev. time between licks in bursts0.50.61.4-0.7-1.2-0.7-0.80.5-0.80.4
Water consumed over 24 hours0.10.10.2-0.2-0.4-0.4-0.40.40.1-0.1
Indifference point 0 sec0.50.92.70.3-0.2-0.7-1.71.40.70.4
Indifference point AUC0.60.72.40.60.21.0-0.6-0.70.01.6
Indifference point function ln k0.20.31.5-0.00.4-0.20.6-0.00.3-1.2
Indifference point function log k0.20.31.5-0.00.4-0.20.6-0.00.3-1.2
Delay discounting total patch changes 0 sec0.40.72.50.4-0.1-0.6-1.61.20.60.3
Delay discounting total patch changes 12 sec0.60.82.00.90.40.3-1.30.60.41.4
Delay discounting total patch changes 18 sec0.10.10.3-0.5-0.5-0.3-0.50.2-0.2-0.0
Delay discounting total patch changes 24 sec1.41.75.31.60.70.4-2.30.90.71.5
Delay discounting total patch changes 6 sec0.60.93.10.6-0.1-0.1-1.80.90.61.2
Delay discounting time to switch 0 sec0.81.22.4-1.2-0.3-1.61.01.10.1-1.5
Delay discounting water rate 0 sec0.40.61.50.2-0.80.7-1.2-0.7-0.31.1
Delay discounting water rate 12 sec0.40.52.40.0-0.7-0.4-1.60.60.40.2
Delay discounting water rate 18 sec0.40.51.6-0.0-1.00.0-1.30.1-0.40.8
Delay discounting water rate 24 sec0.50.71.7-0.2-1.00.7-0.5-1.1-1.30.4
Delay discounting water rate 6 sec0.71.02.11.1-0.31.2-1.4-0.8-0.61.1
Locomotor activity0.40.63.10.5-0.20.5-0.80.00.11.7
Locomotor testing distance0.40.61.51.21.00.6-0.20.31.00.7
Locomotor testing rearing0.30.41.11.10.80.6-0.2-0.10.90.3
Light reinforcement 10.20.31.10.60.10.2-0.70.30.31.1
Light reinforcement 20.70.92.4-0.0-0.1-1.0-1.11.51.10.4
Reaction time number correct0.30.51.6-0.7-1.3-0.0-0.2-0.5-1.00.0
Reaction time mean minus median0.50.72.2-1.1-1.5-0.6-0.3-0.0-0.90.2
Reaction time mean minus median AUC0.30.30.8-0.4-0.90.0-0.2-0.4-0.90.6
Reaction time num false alarms1.31.85.12.31.91.2-0.6-0.11.01.1
Reaction time num false alarms AUC1.01.44.12.01.50.8-0.90.30.90.9
Reaction time trials correct on left0.30.51.6-0.7-1.3-0.0-0.2-0.5-1.00.0
Reaction time trials on left0.40.51.7-0.8-1.3-0.1-0.2-0.5-1.00.0
Reaction time mean0.50.71.6-0.4-0.20.71.1-1.3-1.1-0.0
Reaction time mean AUC0.50.61.70.0-0.00.90.8-1.3-1.10.2
Median of all reaction times0.60.92.1-0.00.31.01.3-1.5-1.1-0.1
Reaction time omissions0.30.41.4-1.2-0.9-0.70.20.2-0.3-0.1
Reaction time false alarm rate1.21.85.02.21.90.9-0.80.41.11.0
Reaction time premature initiation rate0.81.02.21.51.41.1-0.2-0.31.01.0
Reaction time premature initiations0.50.81.41.20.71.1-0.4-0.60.41.2
Std. dev. reaction times0.20.30.9-0.2-0.60.4-0.0-0.8-0.90.5
Reaction time trials completed0.40.51.7-0.8-1.3-0.1-0.2-0.5-1.00.0
Reaction time trials AUC0.50.72.3-0.9-1.5-0.1-0.2-0.7-1.2-0.1
Social response proportion0.50.61.4-0.6-1.2-0.3-1.10.1-0.70.5
Social responses0.50.62.00.3-0.80.1-1.40.3-0.71.0
Social time0.60.71.30.7-0.40.9-1.1-0.8-0.71.0
Conditioned locomotion0.50.61.70.71.30.40.70.20.60.9
Cocaine response after cond. corrected0.40.40.70.6-0.20.8-0.7-0.8-0.80.5
Cocaine response after cond. not corrected0.10.10.40.30.20.40.1-0.6-0.1-0.4
Cocaine response before conditioning1.21.43.1-1.10.2-1.21.30.81.3-1.7
Saline control response0.30.41.10.50.80.50.3-0.11.10.8
Condit. Reinf. active minus inactive responses0.30.40.9-0.5-0.4-0.7-0.40.80.51.0
Condit. Reinf. active-inactive response ratio0.40.41.3-1.1-1.0-0.30.4-0.4-0.7-0.0
Condit. Reinf. active responses0.40.62.4-0.1-0.5-0.3-1.00.70.21.5
Condit. Reinf. inactive responses0.50.62.20.80.50.2-0.70.60.71.5
Condit. Reinf. lever presses0.81.23.50.6-0.21.3-0.8-1.1-0.71.9
Condit. Reinf. lever reinforcers received0.40.62.50.1-0.3-0.2-1.00.70.31.6
Pavlov. Cond. lever latency0.10.10.30.30.50.20.3-0.10.1-0.5
Pavlov. Cond. magazine entry latency0.40.51.3-0.8-1.10.0-0.2-0.6-0.90.0
Pavlov. Cond. change in total contacts0.10.20.5-0.2-0.5-0.4-0.70.50.30.2
Pavlov. Cond. index score0.20.30.9-0.8-0.9-0.1-0.1-0.4-0.60.2
Pavlov. Cond. latency score0.10.20.6-0.8-0.6-0.20.3-0.3-0.3-0.1
Pavlov. Cond. lever contacts0.30.41.0-0.5-1.0-0.2-0.80.1-0.40.9
Pavlov. Cond. magazine entry number0.40.51.31.11.10.5-0.10.10.50.4
Pavlov. Cond. intertrial magazine entries0.20.20.80.40.40.50.5-0.3-0.00.9
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.7-0.80.0-0.1-0.5-0.60.4
Pavlov. Cond. response bias0.50.72.2-0.7-1.5-0.4-1.10.2-0.70.7
Conditioned reinforcement - actives0.40.40.80.6-0.10.5-0.7-0.2-0.80.9
Conditioned reinforcement - inactives1.11.32.71.11.01.70.7-1.5-0.70.7
Conditioned locomotion2.02.45.20.4-1.60.8-2.3-0.7-2.11.7
Intermittent access intake day 1-15 change0.50.40.9-0.9-0.9-0.9-0.20.5-0.4-0.4
Intermittent access intake escalation0.40.41.2-0.5-1.0-0.4-0.40.1-1.1-0.1
Intermittent access intake escalation 21.51.53.70.3-1.01.1-0.8-1.3-1.91.5
Intermitt. access day 1 inactive lever presses2.83.08.91.53.00.00.81.32.70.2
Intermitt. access day 15 inactive lever presses1.31.55.10.11.11.12.2-1.60.0-0.4
Intermitt. access escalation Index1.81.65.9-1.2-0.3-0.61.8-0.3-0.7-2.4
Intermittent access day 1 total infusions1.11.22.61.40.41.6-0.7-1.2-1.01.1
Intermittent access day 15 total infusions1.51.62.81.2-0.11.6-0.8-1.4-1.71.4
Intermittent access terminal intake (last 3 days)3.13.46.41.7-0.12.5-0.8-2.3-2.41.8
Intermittent access total infusions1.51.73.11.2-0.21.7-0.8-1.5-1.81.1
Intermittent access day 1 locomotion0.70.71.41.10.31.2-0.4-0.8-0.90.6
Intermittent access day 15 total locomotion3.13.36.52.50.72.5-1.4-1.6-1.12.1
Intermittent access total locomotion1.61.82.81.3-0.31.6-1.4-1.3-1.71.3
Intermittent access standard deviation0.30.41.20.4-0.20.3-1.10.1-0.11.0
Cocaine induced anxiety0.80.91.5-0.9-0.70.21.2-1.2-1.2-0.9
Post-drug Anxiety0.50.51.10.1-0.40.80.1-1.0-1.00.9
Baseline Anxiety0.60.62.20.80.20.1-1.50.70.40.8
Lifetime Intake0.91.02.60.6-0.70.8-1.1-0.8-1.60.9
Incentive Sensitization - Responses1.81.83.71.30.81.90.6-1.8-1.51.0
Incentive Sensitization - Breakpoint1.91.94.01.30.72.00.6-1.9-1.61.1
Progressive ratio test 1 active lever presses2.62.76.10.9-1.31.5-1.7-1.5-2.51.7
Progressive ratio test 1 breakpoint2.12.25.20.8-1.31.2-1.7-1.2-2.31.4
Progressive ratio test 1 inactive lever presses1.41.54.11.82.01.10.1-0.10.91.0
Progressive ratio test 2 active lever presses2.93.15.21.90.22.3-1.1-1.7-1.92.2
Progressive ratio test 2 breakpoint1.71.93.71.60.31.8-0.9-1.2-1.21.9
Progressive ratio test 2 inactive lever presses2.32.65.71.91.32.4-0.1-1.7-0.62.0
Total sessions with >9 infusions2.02.24.4-1.4-2.1-1.8-1.21.3-1.0-1.1
Short access day 1 total inactive lever presses0.60.71.61.11.31.00.4-0.50.10.7
Short access day 10 total inactive lever presses2.12.36.40.82.50.41.80.12.3-0.5
Short access day 1 total infusions0.20.20.5-0.0-0.6-0.2-0.70.2-0.50.3
Short access day 10 total infusions0.40.51.60.7-0.40.4-1.3-0.0-0.80.6
Short access total infusions0.60.61.4-0.6-1.2-0.7-0.90.5-0.90.0
Short access day 1 locomotion1.61.74.4-0.5-2.1-0.4-2.00.2-1.70.3
Short access day 10 total locomotion0.50.51.61.20.81.0-0.3-0.5-0.50.1
Short access total locomotion0.30.30.9-0.1-0.7-0.2-0.90.2-0.9-0.4
Compulsive drug intake2.01.94.7-1.00.5-1.71.11.62.2-1.1
One hour access (0.3 mA shock)2.83.36.00.6-1.71.5-1.9-1.6-2.42.3
One hour access (shock baseline)3.54.19.11.0-1.51.9-2.0-1.8-3.02.3
Number of responses in last shaping day1.21.23.5-0.8-0.5-1.7-0.61.90.9-0.2
Context. condit. distance diff. score3.13.810.33.03.21.80.5-0.31.90.7
Locomotion velocity, session 10.80.82.4-0.5-0.3-1.3-0.31.51.10.4
Locomotion distance, session 10.91.23.40.91.0-0.2-0.71.31.91.0
Locomotion velocity, session 20.40.41.50.10.3-0.2-0.10.70.91.2
Locomotion distance, session 20.50.71.90.80.40.0-1.00.80.91.4
Locomotion velocity, session 30.70.81.30.70.4-0.3-1.01.11.11.2
Locomotion distance, session 32.12.37.0-0.6-0.3-2.1-0.92.71.80.5
Stereotopy head waving bouts, day 30.30.42.10.6-0.50.1-1.40.2-0.30.2
Stereotopy head waving duration, day 30.30.41.11.10.30.6-1.0-0.10.10.2
Locomotion velocity, session 70.40.50.90.80.70.5-0.10.10.91.0
Locomotion distance, session 70.30.41.20.10.3-0.4-0.10.91.10.9
Stereotopy head waving bouts, day 70.20.31.1-0.2-0.0-0.6-0.10.50.3-1.0
Stereotopy head waving duration, day 70.10.10.30.0-0.1-0.4-0.30.5-0.1-0.6
Locomotion velocity, session 82.83.410.51.52.5-0.50.22.03.20.6
Locomotion distance, session 82.43.68.82.53.00.80.20.92.70.9
Degree of sensitization distance2.02.04.81.21.12.11.1-2.2-0.80.1
Degree of sensitization stereotypy0.20.20.5-0.2-0.4-0.4-0.30.3-0.3-0.7
Condit. Reinf. active minus inactive responses0.80.92.5-0.9-1.6-0.6-0.6-0.1-1.3-0.6
Condit. Reinf. active-inactive response ratio1.01.13.6-0.7-1.1-0.5-0.3-0.3-1.3-1.9
Condit. Reinf. active responses0.30.41.3-0.6-1.2-0.4-0.50.2-0.60.3
Condit. Reinf. inactive responses0.30.31.6-0.3-0.1-0.10.20.30.51.3
Incentive salience index mean0.20.20.7-0.5-0.8-0.5-0.30.3-0.3-0.3
Condit. Reinf. lever presses0.30.40.9-0.6-0.1-0.90.50.90.9-0.1
Time in familiar zone, hab. session 11.11.03.30.31.1-0.60.41.41.80.4
Time in novel zone, hab. session 12.72.69.1-0.4-1.91.0-0.9-2.0-3.00.2
Total zone transitions, hab. session 11.41.96.30.8-0.5-0.3-2.51.30.62.1
Total locomotion distance, hab. session 11.42.06.11.70.71.1-1.70.10.82.5
Locomotion velocity, hab. session 11.21.73.51.50.80.5-1.60.71.51.9
Time in familiar zone, hab. session 20.20.20.6-0.5-0.2-0.80.30.70.2-0.5
Time in novel zone, hab. session 20.50.51.50.40.01.1-0.2-1.2-0.70.3
Total zone transitions, hab. session 20.50.71.41.01.20.90.8-0.60.7-0.3
Total locomotion distance, hab. session 21.11.53.21.71.51.80.5-1.30.50.2
Locomotion velocity, hab. session 20.91.23.01.71.41.50.0-0.70.80.5
Novel to familiar place preference ratio0.20.21.00.1-0.4-0.0-1.00.20.10.6
Novelty place preference0.40.41.6-0.1-0.8-0.1-1.30.2-0.10.7
Time in novel zone, NPP test0.50.52.1-0.0-0.8-0.0-1.40.2-0.31.0
Total zone transitions, NPP test0.40.52.10.00.7-0.40.60.61.40.1
Total locomotion distance, NPP test0.30.52.20.50.5-0.1-0.40.61.50.3
Locomotion velocity, NPP test0.40.63.00.30.7-0.3-0.20.81.70.0
Pavlov. Cond. lever latency0.40.51.7-0.8-0.5-0.50.4-0.1-0.5-1.3
Pavlov. Cond. magazine entry latency0.20.20.60.30.1-0.3-0.50.80.40.4
Pavlov. Cond. change in total contacts0.20.20.50.60.60.40.2-0.00.30.7
Pavlov. Cond. index score0.40.61.10.50.4-0.2-0.71.01.01.0
Pavlov. Cond. latency score0.30.41.00.50.6-0.1-0.30.71.01.0
Pavlov. Cond. lever contacts0.40.51.70.70.60.6-0.1-0.00.61.3
Pavlov. Cond. magazine entry number0.20.20.6-0.3-0.20.30.4-0.8-0.6-0.3
Pavlov. Cond. intertrial magazine entries0.50.62.40.70.10.8-0.8-0.30.21.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.20.60.5-0.2-0.61.01.01.1
Pavlov. Cond. response bias0.30.31.50.50.10.2-0.60.40.21.2
Bone: apparent density2.03.36.3-1.9-0.2-2.51.02.32.3-1.2
Bone surface0.81.42.5-1.5-0.1-1.31.60.71.1-1.3
Bone volume0.50.92.0-0.90.4-0.91.20.81.4-0.6
Bone: connectivity density2.53.97.7-1.8-0.3-2.80.72.72.6-1.4
Bone: cortical apparent density0.50.71.6-0.5-0.8-1.2-1.01.30.2-0.0
Bone: cortical area0.81.33.00.41.60.41.7-0.31.5-0.7
Bone: cortical porosity0.70.81.6-0.8-0.6-1.3-0.31.10.1-1.2
Bone: cortical porosity0.80.92.4-1.0-0.6-1.3-0.11.00.1-1.6
Bone: cortical thickness1.93.17.6-0.11.9-1.02.11.22.8-1.9
Bone: cortical thickness0.50.62.1-0.10.70.61.4-0.90.7-0.6
Bone: cortical tissue density0.60.81.7-0.6-1.0-1.2-1.11.30.0-0.0
Bone: elastic displacement1.11.33.0-0.61.0-0.81.70.51.4-1.4
Bone: elastic work1.72.23.1-1.70.2-1.81.71.21.4-1.8
Bone: endosteal estimation1.43.06.80.7-0.62.3-0.3-2.6-2.21.7
Bone: endosteal perimeter0.51.13.0-0.1-0.61.20.3-1.7-1.41.0
Bone: final force0.20.41.0-1.0-0.6-0.00.8-0.7-0.1-0.3
Bone: final moment0.30.41.1-1.0-1.0-0.00.4-0.7-0.5-0.2
Bone: marrow area1.32.76.30.7-0.52.2-0.3-2.5-2.11.6
Bone: maximum diameter0.30.62.4-0.10.60.61.5-1.00.1-0.4
Bone: maximum force0.20.30.8-0.7-0.20.10.9-0.70.2-0.4
Bone: maximum moment0.20.30.6-0.8-0.60.10.4-0.8-0.2-0.3
Bone: minimum diameter3.76.815.11.5-0.63.7-0.8-3.9-2.82.8
Bone: periosteal estimation0.51.13.30.50.41.60.8-1.8-0.60.6
Bone: periosteal perimeter0.10.20.60.20.40.60.7-0.80.20.1
Bone: post-yield work0.70.92.0-0.2-1.20.8-0.7-1.2-1.40.7
Bone: stiffness0.40.61.80.5-0.50.6-1.3-0.30.01.3
Bone: tissue strength0.40.41.10.2-0.60.3-1.1-0.3-0.50.7
Bone: trabecular number1.42.24.9-1.4-0.4-2.20.22.21.9-0.6
Bone: trabecular spacing0.70.92.11.51.11.3-0.2-0.8-0.20.7
Bone: trabecular thickness0.40.51.1-0.8-0.1-0.90.40.81.1-0.3
Bone: trabecular tissue density0.10.10.2-0.3-0.5-0.2-0.1-0.0-0.4-0.5
Breakpoint value in progressive ratio session0.10.10.7-0.10.20.10.8-0.3-0.1-0.2
Distance traveled before self-admin1.11.22.21.2-0.11.4-1.2-0.9-1.50.8
Distance traveled after self-admin3.23.66.91.9-0.12.6-1.4-2.2-2.31.5
Delta time in closed arm before/after self-admin0.40.41.2-0.5-0.1-0.80.10.60.3-1.1
Delta time in open arm before/after self-admin0.80.83.90.5-0.10.8-0.6-0.5-0.32.0
Diff in mean of infusions in LGA sessions0.70.83.4-0.10.80.31.8-0.8-0.5-0.9
Extinction: sum of active levers before priming0.30.31.50.4-0.50.0-1.20.3-0.50.1
Active lever presses in extinction session 61.01.03.1-0.5-1.50.3-0.6-1.0-1.80.2
Delta distance traveled before/after self-admin0.10.10.40.0-0.20.50.1-0.7-0.50.1
Delta ambulatory time before/after self-admin0.10.10.2-0.2-0.10.20.3-0.5-0.4-0.4
Time in closed arm before self-admin1.21.42.41.31.61.50.9-1.10.40.9
Time in closed arm after self-admin3.03.28.22.22.91.91.4-1.01.50.5
Time in open arm before self-admin1.51.63.2-1.7-1.4-1.6-0.00.8-0.7-1.8
Time in open arm after self-admin1.21.33.2-0.7-1.8-0.7-1.50.5-1.21.1
Sum of active levers in priming session hrs 5-60.10.10.50.20.1-0.3-0.40.70.20.1
Time to tail flick, vehicle, before self-admin1.01.02.2-0.4-0.91.00.1-1.5-1.41.1
Time to tail flick, vehicle, after self-admin1.21.22.71.61.21.3-0.7-0.40.51.4
Time to tail flick, test, before self-admin0.40.41.40.61.20.30.8-0.00.5-0.2
Time to tail flick, test, after self-admin2.72.74.91.3-0.32.2-0.7-2.1-2.02.0
Delta time to tail flick, vehicle, before/after SA0.90.81.51.11.0-0.0-0.91.01.20.6
Delta time to tail flick, test, before/after SA1.91.74.40.8-0.61.4-1.1-1.2-1.32.1
Ambulatory time before self-admin1.71.83.01.70.01.5-1.7-0.8-1.31.4
Ambulatory time after self-admin3.23.56.11.9-0.32.5-1.9-1.9-2.11.8
Total heroin consumption1.31.63.50.8-0.41.7-0.3-1.9-1.80.5
Area under the delay curve0.70.72.10.1-0.6-0.3-1.40.7-0.21.5
Delay disc. indifference point, 0s delay0.40.40.8-0.2-0.8-0.3-0.90.4-0.40.9
Delay disc. indifference point, 16s delay0.50.51.20.2-0.0-0.4-0.90.90.31.1
Delay disc. indifference point, 2s delay1.01.14.40.6-0.60.6-1.3-0.2-0.72.1
Delay disc. indifference point, 24s delay1.11.04.20.4-0.9-0.1-2.00.4-1.30.5
Delay disc. indifference point, 4s delay1.51.54.90.4-0.7-0.1-2.10.70.12.2
Delay disc. indifference point, 8s delay0.90.92.3-1.1-1.0-1.5-0.61.40.10.2
Delay discount exponential model param0.70.82.3-0.20.60.21.5-0.60.3-1.5
Delay discount hyperbolic model param1.01.13.5-0.40.60.11.7-0.60.2-1.9
Fecal boli incidents, locomotor time 10.70.82.2-1.5-1.1-0.50.9-0.5-0.8-0.4
Change in fecal boli incidents, locomotor task0.50.51.1-0.7-0.7-0.10.4-0.5-1.1-1.0
Time >=10cm from walls, locomotor time 10.80.81.9-1.4-1.3-0.50.2-0.3-1.3-0.2
Bouts of movement, locomotor time 10.30.30.60.60.30.7-0.0-0.8-0.6-0.8
Total resting periods, locomotor time 10.30.40.80.3-0.20.6-0.3-0.8-0.9-0.7
Rest time, locomotor task time 10.80.82.4-0.1-0.80.90.1-1.5-1.4-0.3
Distance moved, locomotor task time 10.60.61.9-0.4-0.1-1.0-0.21.41.00.5
Vertical activity count, locomotor time 10.40.51.40.4-0.3-0.1-1.00.6-0.21.2
Time >=10cm from walls, locomotor time 20.30.31.2-1.1-0.4-0.60.60.1-0.0-0.5
Bouts of movement, locomotor time 20.70.71.91.40.61.1-1.0-0.5-0.30.5
Total resting periods, locomotor time 20.50.51.41.20.41.0-0.8-0.6-0.30.4
Rest time, locomotor task time 20.91.12.61.40.61.6-0.2-1.5-0.8-0.2
Distance moved, locomotor task time 21.82.05.0-1.6-0.7-2.20.12.11.2-0.6
Vertical activity count, locomotor time 21.01.12.0-1.0-1.4-1.3-0.91.2-0.20.8
Weight adjusted by age1.21.33.3-1.8-1.3-1.60.10.9-0.2-1.1
Seeking ratio, delayed vs. immediate footshock0.80.92.01.40.61.3-0.9-0.7-0.40.9
Locomotion in novel chamber0.40.52.00.4-0.2-0.3-1.40.80.20.6
Locomotion in novel chamber post-restriction0.70.82.4-0.0-1.10.4-1.2-0.4-0.71.6
Progressive ratio0.40.51.2-0.5-0.0-1.00.20.90.3-1.1
Food seeking constrained by brief footshock0.20.20.5-0.4-0.2-0.7-0.50.70.4-0.4
Seeking ratio, punishment vs. effort0.20.20.60.40.30.6-0.1-0.40.10.8
Run reversals in cocaine runway, females0.10.10.30.10.1-0.00.20.20.60.2
Run reversals in cocaine runway, males0.30.31.0-0.8-0.1-0.61.00.2-0.3-0.4
Latency to leave start box in cocaine runway1.41.54.01.20.21.9-0.1-2.0-1.20.1
Latency to leave start box in cocaine runway, F2.12.35.71.90.62.4-0.6-2.0-1.11.1
Latency to leave start box in cocaine runway, M1.41.33.0-1.5-1.1-0.41.1-0.7-1.0-1.7
Cd content in liver0.60.71.7-0.9-0.4-0.01.0-0.8-0.8-1.3
Co content in liver0.81.01.80.6-0.61.2-1.1-1.3-1.10.6
Cu content in liver0.70.82.01.10.51.0-0.9-0.30.51.4
Fe content in liver1.61.94.1-2.0-1.5-2.0-0.31.60.60.4
K content in liver1.71.73.71.40.90.1-1.31.31.51.9
Mg content in liver1.41.56.21.30.70.8-0.80.20.82.5
Mn content in liver0.60.71.90.51.2-0.30.51.01.40.4
Na content in liver2.32.47.10.4-0.8-1.0-2.72.01.51.4
Rb content in liver0.60.72.1-0.8-1.10.00.2-0.8-1.5-0.4
Se content in liver1.72.03.81.91.81.0-0.30.31.51.9
Sr content in liver1.91.84.90.41.41.02.2-1.50.3-1.4
Zn content in liver0.80.91.91.41.10.8-0.50.10.71.2