Map6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000027204 0.03 0.02 8.2e-03 0.01 0 -0 0 3.2e-02 1.9e-01 6.8e-01 2.0e-01
2 Brain gene expression ENSRNOG00000027204 0.14 0.08 4.9e-12 0.13 0.12 0.12 0.13 8.5e-12 1.5e-11 2.2e-11 7.7e-12
3 Brain mRNA stability ENSRNOG00000027204 0.09 0.05 4.2e-08 0.08 0.09 0.09 0.09 7.7e-08 5.3e-09 7.6e-09 2.8e-08
4 Liver intron excision ratio chr1:153570315:153604923 0.04 0.03 2.4e-04 0.02 0.02 0.02 0.01 3.0e-03 6.0e-03 3.4e-03 1.3e-02
5 Liver intron excision ratio chr1:153570315:153614082 0.04 0.03 2.7e-04 0.02 0.01 0.02 0.01 3.3e-03 6.9e-03 3.5e-03 1.3e-02
6 NAcc gene expression ENSRNOG00000027204 0.2 0.12 7.0e-08 0.1 0.09 0.08 0.09 1.1e-07 2.4e-07 1.2e-06 1.9e-07
7 OFC mRNA stability ENSRNOG00000027204 0.41 0.27 9.7e-05 0.09 0.14 0.09 0.14 3.9e-03 3.2e-04 3.6e-03 4.0e-04
8 PL gene expression ENSRNOG00000027204 0.06 0.04 9.5e-05 0.04 0.04 0.04 0.04 1.2e-03 2.3e-04 1.0e-03 1.1e-03
9 PL mRNA stability ENSRNOG00000027204 0.08 0.05 2.4e-05 0.06 0.04 0.05 0 1.7e-05 7.6e-04 1.8e-04 3.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.00.10.7-0.80.00.1-0.20.20.0-0.40.40.1
BMI without tail1.43.07.7-1.61.0-1.21.5-1.51.4-2.62.8-1.2
Body weight0.62.46.5-1.90.8-0.90.8-0.81.1-2.52.6-1.1
Epididymis fat weight0.40.94.7-2.2-0.60.4-0.40.4-0.3-1.21.20.1
Glucose0.00.10.20.2-0.10.2-0.20.2-0.20.4-0.50.2
Heart weight0.91.31.61.11.3-1.21.2-1.21.3-0.70.7-1.1
Left kidney weight1.44.07.2-0.31.7-1.91.9-1.91.9-2.72.5-2.2
Right kidney weight0.82.44.8-0.31.2-1.41.4-1.41.3-2.22.1-1.8
Tail length3.611.022.2-1.52.4-2.83.2-3.22.9-4.74.7-3.1
Length with tail1.34.611.6-1.81.2-1.51.6-1.61.6-3.43.4-1.9
Length without tail0.51.01.6-0.3-0.91.0-1.31.3-1.10.9-1.10.8
Liver weight, left0.40.73.4-1.9-0.60.5-0.30.3-0.3-0.91.10.3
Liver weight, right1.22.08.5-2.9-1.31.1-1.11.1-1.0-1.11.20.8
Parametrial fat weight0.40.84.3-2.1-0.40.5-0.40.4-0.1-0.71.00.7
Retroperitoneal fat weight1.96.130.5-5.5-2.21.9-1.61.6-1.5-1.62.01.5
Intraocular pressure0.30.41.61.30.7-0.50.5-0.50.40.6-0.6-0.3
Extensor digitorum longus weight0.20.82.6-1.50.1-0.30.4-0.40.6-1.31.6-0.1
Soleus weight0.61.75.1-2.10.2-0.40.6-0.60.6-2.02.3-0.4
Tibialis anterior weight0.20.81.7-0.50.7-0.80.8-0.81.0-1.21.3-0.7
Tibia length1.13.07.82.82.0-1.91.6-1.61.7-0.1-0.2-1.8
Number of licking bursts4.14.96.7-2.6-2.42.5-2.42.4-2.21.2-1.02.5
Food consumed during 24 hour testing period2.42.95.32.31.7-1.81.9-1.91.3-1.10.7-2.0
Times rat made contact with spout0.30.31.2-1.1-0.40.20.1-0.1-0.1-0.70.90.2
Mean time between licks in bursts5.88.112.30.42.8-2.92.8-2.82.7-3.53.1-3.4
Mean num. licks in bursts3.94.76.12.32.3-2.42.5-2.52.2-1.51.3-2.3
Std. dev. time between licks in bursts2.12.65.1-0.61.3-1.41.6-1.61.3-2.32.1-1.7
Water consumed over 24 hours0.81.01.6-0.4-1.31.1-0.90.9-1.20.8-0.61.1
Indifference point 0 sec5.58.911.72.33.4-3.43.1-3.13.4-2.22.1-3.3
Indifference point AUC0.40.51.0-0.80.4-0.40.6-0.60.6-1.01.0-0.4
Indifference point function ln k0.91.24.82.21.2-1.11.0-1.00.80.3-0.5-0.9
Indifference point function log k0.91.24.82.21.2-1.11.0-1.00.80.3-0.5-0.9
Delay discounting total patch changes 0 sec4.47.29.52.03.1-3.12.8-2.83.1-2.01.9-3.0
Delay discounting total patch changes 12 sec2.53.44.10.21.8-1.91.9-1.92.0-2.02.0-1.9
Delay discounting total patch changes 18 sec2.93.84.50.71.9-2.12.1-2.12.1-2.02.0-2.1
Delay discounting total patch changes 24 sec0.60.71.7-0.00.8-0.90.7-0.70.7-1.10.9-1.3
Delay discounting total patch changes 6 sec1.11.73.11.21.6-1.51.4-1.41.8-0.70.8-1.2
Delay discounting time to switch 0 sec4.56.98.8-1.5-2.92.9-2.92.9-3.02.3-2.22.8
Delay discounting water rate 0 sec3.25.06.51.92.5-2.52.4-2.42.5-1.61.4-2.4
Delay discounting water rate 12 sec1.72.53.92.01.8-1.81.7-1.71.7-0.70.6-1.6
Delay discounting water rate 18 sec0.81.11.40.81.1-1.21.1-1.11.1-0.90.8-1.1
Delay discounting water rate 24 sec0.70.94.32.11.0-0.90.7-0.70.70.4-0.5-0.7
Delay discounting water rate 6 sec0.50.82.01.41.0-1.00.9-0.91.0-0.10.0-0.7
Locomotor activity0.91.52.01.41.2-1.31.2-1.21.2-0.90.9-1.3
Locomotor testing distance2.44.05.61.52.1-2.22.0-2.02.1-1.81.7-2.4
Locomotor testing rearing1.42.13.60.11.3-1.51.3-1.31.4-1.91.8-1.7
Light reinforcement 11.52.73.7-1.7-1.91.8-1.91.9-1.80.8-0.71.6
Light reinforcement 20.20.20.40.3-0.40.4-0.60.6-0.40.6-0.60.3
Reaction time number correct0.30.52.01.4-0.10.1-0.30.3-0.30.9-1.10.0
Reaction time mean minus median1.21.52.00.41.4-1.31.3-1.31.4-1.21.3-1.0
Reaction time mean minus median AUC1.11.42.11.01.5-1.31.2-1.21.3-0.91.0-1.1
Reaction time num false alarms1.41.93.6-1.9-1.61.5-1.41.4-1.50.4-0.31.3
Reaction time num false alarms AUC1.01.32.1-1.3-1.41.3-1.21.2-1.40.5-0.51.0
Reaction time trials correct on left0.30.52.01.4-0.10.1-0.30.3-0.30.9-1.10.0
Reaction time trials on left0.30.52.01.4-0.10.1-0.30.3-0.20.9-1.10.0
Reaction time mean0.40.51.9-1.4-0.60.7-0.50.5-0.3-0.00.31.0
Reaction time mean AUC0.70.91.9-1.4-1.01.1-1.01.0-0.80.4-0.11.3
Median of all reaction times0.91.22.6-1.6-1.11.2-1.11.1-0.80.5-0.21.5
Reaction time omissions0.10.20.7-0.8-0.30.3-0.50.5-0.2-0.10.20.4
Reaction time false alarm rate1.01.53.9-2.0-1.41.3-1.21.2-1.30.2-0.11.1
Reaction time premature initiation rate3.34.48.0-0.42.0-2.12.0-2.02.4-2.62.8-1.8
Reaction time premature initiations2.13.04.40.61.8-1.91.7-1.72.1-1.81.9-1.6
Std. dev. reaction times0.71.02.2-0.70.9-0.80.9-0.91.0-1.31.5-0.6
Reaction time trials completed0.30.52.01.4-0.10.1-0.30.3-0.20.9-1.10.0
Reaction time trials AUC0.20.31.61.3-0.10.1-0.20.2-0.20.7-0.9-0.1
Social response proportion0.40.40.7-0.9-0.80.7-0.80.8-0.60.00.00.5
Social responses0.40.52.1-1.5-0.70.5-0.50.5-0.4-0.70.70.1
Social time3.95.27.1-0.9-2.62.4-2.72.7-2.52.0-2.12.1
Conditioned locomotion0.10.10.30.4-0.10.2-0.20.2-0.20.6-0.50.3
Cocaine response after cond. corrected1.71.93.7-1.9-1.41.5-1.61.6-1.40.5-0.51.3
Cocaine response after cond. not corrected0.80.91.4-1.0-0.91.0-1.21.2-1.00.5-0.60.7
Cocaine response before conditioning0.91.13.71.91.0-1.11.0-1.00.9-0.1-0.0-1.1
Saline control response1.82.33.40.71.5-1.71.5-1.51.6-1.71.5-1.8
Condit. Reinf. active minus inactive responses6.78.312.11.63.2-3.23.0-3.03.0-2.72.4-3.5
Condit. Reinf. active-inactive response ratio1.01.12.11.01.2-1.21.0-1.01.0-0.80.5-1.5
Condit. Reinf. active responses9.613.418.11.74.0-4.03.7-3.73.9-3.73.4-4.3
Condit. Reinf. inactive responses6.37.99.80.92.9-3.02.8-2.82.9-3.13.0-3.1
Condit. Reinf. lever presses17.724.432.23.45.7-5.55.3-5.35.5-4.03.7-5.4
Condit. Reinf. lever reinforcers received10.414.720.22.04.2-4.23.9-3.94.1-3.73.3-4.5
Pavlov. Cond. lever latency17.724.332.8-3.8-5.75.6-5.15.1-5.53.8-3.45.6
Pavlov. Cond. magazine entry latency4.45.17.52.22.7-2.62.4-2.42.7-1.21.1-2.3
Pavlov. Cond. change in total contacts11.816.422.93.64.8-4.64.1-4.14.4-2.82.3-4.8
Pavlov. Cond. index score13.818.124.93.55.0-4.94.5-4.54.8-3.02.7-4.7
Pavlov. Cond. latency score12.415.722.03.44.7-4.54.2-4.24.5-2.72.4-4.4
Pavlov. Cond. lever contacts18.726.035.53.96.0-5.85.4-5.45.7-3.83.5-5.7
Pavlov. Cond. magazine entry number6.47.811.0-3.0-3.33.2-2.92.9-3.11.5-1.23.2
Pavlov. Cond. intertrial magazine entries0.50.61.8-1.20.0-0.20.4-0.40.1-1.31.4-0.4
Pavlov. Cond. lever-magazine prob. diff.12.916.622.93.34.8-4.74.3-4.34.6-3.02.6-4.6
Pavlov. Cond. response bias19.126.335.74.16.0-5.85.4-5.45.8-3.83.4-5.7
Conditioned reinforcement - actives1.31.33.51.91.3-1.21.1-1.11.1-0.0-0.1-1.1
Conditioned reinforcement - inactives0.60.70.9-0.9-0.90.9-1.01.0-0.90.4-0.50.8
Conditioned locomotion0.80.94.62.10.9-0.80.6-0.60.60.5-0.7-0.6
Intermittent access intake day 1-15 change0.80.81.41.21.2-1.01.0-1.00.9-0.20.1-0.8
Intermittent access intake escalation1.11.12.01.41.3-1.11.2-1.21.1-0.20.1-1.0
Intermittent access intake escalation 20.50.50.80.50.9-0.80.9-0.90.8-0.50.5-0.7
Intermitt. access day 1 inactive lever presses0.60.71.0-0.8-1.00.9-1.01.0-0.80.4-0.40.8
Intermitt. access day 15 inactive lever presses0.20.20.40.5-0.40.3-0.50.5-0.50.6-0.70.3
Intermitt. access escalation Index0.20.20.20.40.4-0.40.4-0.40.5-0.30.4-0.3
Intermittent access day 1 total infusions0.60.70.90.40.9-0.90.9-0.90.9-0.91.0-0.8
Intermittent access day 15 total infusions1.11.22.11.31.4-1.21.2-1.21.2-0.50.4-1.0
Intermittent access terminal intake (last 3 days)1.01.11.80.91.3-1.11.2-1.21.1-0.60.7-1.0
Intermittent access total infusions0.50.50.80.50.9-0.80.8-0.80.8-0.50.6-0.7
Intermittent access day 1 locomotion0.10.10.30.50.00.1-0.20.2-0.10.4-0.30.2
Intermittent access day 15 total locomotion0.80.82.31.51.1-0.90.9-0.90.8-0.10.0-0.8
Intermittent access total locomotion0.30.30.50.70.7-0.60.6-0.60.6-0.30.3-0.6
Intermittent access standard deviation0.10.10.2-0.10.2-0.30.3-0.30.2-0.50.4-0.4
Cocaine induced anxiety1.82.03.0-1.1-1.71.6-1.51.5-1.51.1-1.01.5
Post-drug Anxiety0.40.50.9-0.9-0.80.8-0.70.7-0.70.3-0.30.7
Baseline Anxiety1.82.02.80.81.7-1.51.5-1.51.5-1.11.1-1.5
Lifetime Intake0.70.71.10.61.1-0.91.0-1.00.9-0.60.6-0.8
Incentive Sensitization - Responses3.03.03.90.91.9-1.92.0-2.01.9-1.51.5-1.8
Incentive Sensitization - Breakpoint2.82.83.71.11.9-1.81.9-1.91.8-1.41.3-1.8
Progressive ratio test 1 active lever presses0.50.50.7-0.6-0.70.8-0.70.7-0.80.7-0.60.8
Progressive ratio test 1 breakpoint0.30.40.5-0.7-0.60.7-0.60.6-0.60.5-0.40.7
Progressive ratio test 1 inactive lever presses0.10.10.1-0.20.3-0.30.3-0.30.4-0.30.3-0.1
Progressive ratio test 2 active lever presses1.11.21.60.51.2-1.21.3-1.31.2-0.90.9-1.0
Progressive ratio test 2 breakpoint1.11.31.70.51.3-1.21.3-1.31.2-1.01.0-1.1
Progressive ratio test 2 inactive lever presses0.40.50.70.80.8-0.80.8-0.80.8-0.30.4-0.6
Total sessions with >9 infusions1.92.13.01.61.7-1.61.7-1.71.5-0.60.6-1.3
Short access day 1 total inactive lever presses0.30.40.6-0.2-0.60.7-0.70.7-0.70.5-0.50.6
Short access day 10 total inactive lever presses0.20.20.3-0.0-0.50.5-0.60.6-0.50.5-0.50.5
Short access day 1 total infusions1.92.02.90.91.7-1.61.6-1.61.5-1.21.1-1.5
Short access day 10 total infusions0.70.81.00.21.0-0.90.9-0.90.9-1.00.9-1.0
Short access total infusions0.70.81.00.21.0-0.91.0-1.00.9-0.90.9-0.8
Short access day 1 locomotion1.01.13.61.91.3-1.00.9-0.90.90.3-0.5-0.8
Short access day 10 total locomotion0.20.20.40.50.6-0.60.4-0.40.5-0.30.2-0.6
Short access total locomotion0.00.00.10.40.3-0.20.2-0.20.20.1-0.2-0.2
Compulsive drug intake0.20.20.70.9-0.0-0.0-0.10.1-0.10.6-0.7-0.1
One hour access (0.3 mA shock)1.72.02.61.41.6-1.61.5-1.51.6-0.90.9-1.5
One hour access (shock baseline)1.11.21.70.81.3-1.21.2-1.21.2-0.90.8-1.1
Number of responses in last shaping day0.60.61.3-0.10.6-0.70.7-0.70.8-1.11.2-0.8
Context. condit. distance diff. score2.12.64.11.92.0-1.91.7-1.72.0-0.40.5-1.4
Locomotion velocity, session 10.91.02.10.6-0.80.9-0.90.9-1.21.2-1.40.5
Locomotion distance, session 10.30.52.21.50.5-0.50.1-0.10.10.3-0.7-0.9
Locomotion velocity, session 20.00.00.10.1-0.10.00.0-0.0-0.3-0.2-0.1-0.4
Locomotion distance, session 20.20.31.01.00.4-0.50.4-0.40.1-0.1-0.2-0.8
Locomotion velocity, session 30.30.41.91.40.5-0.50.3-0.30.40.4-0.6-0.6
Locomotion distance, session 30.70.73.21.80.8-0.70.6-0.60.50.4-0.7-0.8
Stereotopy head waving bouts, day 30.20.21.0-1.0-0.50.4-0.40.4-0.4-0.30.30.3
Stereotopy head waving duration, day 30.10.20.30.50.5-0.40.5-0.50.5-0.10.1-0.3
Locomotion velocity, session 70.30.40.6-0.1-0.50.5-0.70.7-0.40.8-0.70.6
Locomotion distance, session 70.00.10.1-0.4-0.20.2-0.30.3-0.10.2-0.10.3
Stereotopy head waving bouts, day 71.31.42.81.71.3-1.31.3-1.31.1-0.50.2-1.4
Stereotopy head waving duration, day 72.12.63.41.71.7-1.81.8-1.81.5-1.10.8-1.8
Locomotion velocity, session 81.21.52.21.11.5-1.31.4-1.41.5-0.70.8-1.0
Locomotion distance, session 81.52.23.71.91.7-1.71.5-1.51.5-0.60.4-1.8
Degree of sensitization distance0.80.83.6-1.9-0.20.1-0.10.10.2-1.11.40.2
Degree of sensitization stereotypy3.13.46.22.52.0-2.02.0-2.01.6-0.90.4-2.2
Condit. Reinf. active minus inactive responses0.50.61.3-0.20.6-0.70.7-0.70.7-1.11.1-0.7
Condit. Reinf. active-inactive response ratio1.51.63.1-0.21.1-1.21.3-1.31.4-1.51.7-1.0
Condit. Reinf. active responses0.10.10.3-0.20.1-0.10.1-0.10.1-0.50.5-0.3
Condit. Reinf. inactive responses0.20.30.50.2-0.50.5-0.60.6-0.70.5-0.70.2
Incentive salience index mean0.40.51.00.00.6-0.70.7-0.70.6-1.01.0-0.8
Condit. Reinf. lever presses0.10.20.40.30.3-0.40.5-0.50.2-0.50.4-0.6
Time in familiar zone, hab. session 10.10.10.3-0.6-0.20.10.0-0.0-0.1-0.40.40.1
Time in novel zone, hab. session 10.10.10.1-0.3-0.10.2-0.30.3-0.10.1-0.00.3
Total zone transitions, hab. session 10.20.21.01.00.3-0.10.1-0.10.10.7-0.60.1
Total locomotion distance, hab. session 10.40.62.7-1.6-0.70.6-0.60.6-0.6-0.60.60.3
Locomotion velocity, hab. session 10.20.31.4-1.2-0.50.4-0.40.4-0.3-0.50.50.2
Time in familiar zone, hab. session 22.12.23.20.51.4-1.51.8-1.81.5-1.51.6-1.2
Time in novel zone, hab. session 21.11.11.80.1-0.90.9-1.41.4-1.11.1-1.40.6
Total zone transitions, hab. session 20.81.13.51.91.2-1.10.8-0.80.90.0-0.3-1.2
Total locomotion distance, hab. session 20.30.41.3-0.90.0-0.20.0-0.00.1-1.21.0-0.6
Locomotion velocity, hab. session 20.30.51.4-1.2-0.1-0.1-0.10.10.0-1.21.0-0.5
Novel to familiar place preference ratio0.00.00.10.20.0-0.0-0.20.2-0.00.2-0.3-0.2
Novelty place preference0.10.10.20.2-0.10.1-0.30.3-0.20.2-0.4-0.2
Time in novel zone, NPP test0.00.10.20.40.1-0.2-0.10.10.00.1-0.3-0.3
Total zone transitions, NPP test0.20.21.11.10.1-0.1-0.10.1-0.10.5-0.7-0.3
Total locomotion distance, NPP test0.60.91.8-1.3-1.00.9-1.21.2-1.1-0.30.00.2
Locomotion velocity, NPP test1.01.52.5-1.6-1.41.2-1.61.6-1.4-0.0-0.20.5
Pavlov. Cond. lever latency1.41.82.5-0.9-1.31.4-1.61.6-1.21.3-1.21.5
Pavlov. Cond. magazine entry latency3.44.35.41.22.2-2.32.2-2.22.3-2.01.8-2.3
Pavlov. Cond. change in total contacts1.01.12.10.81.0-1.11.0-1.00.9-1.10.8-1.4
Pavlov. Cond. index score3.54.55.61.22.1-2.32.4-2.42.1-2.12.0-2.3
Pavlov. Cond. latency score3.44.35.41.22.1-2.32.3-2.32.1-2.01.9-2.3
Pavlov. Cond. lever contacts1.61.92.50.61.2-1.41.6-1.61.2-1.61.4-1.6
Pavlov. Cond. magazine entry number3.84.75.8-1.5-2.32.4-2.42.4-2.31.9-1.72.4
Pavlov. Cond. intertrial magazine entries2.22.64.1-0.8-1.81.8-1.81.8-2.01.3-1.41.4
Pavlov. Cond. lever-magazine prob. diff.2.93.64.51.01.8-2.02.1-2.11.9-1.91.8-2.1
Pavlov. Cond. response bias1.51.82.40.61.2-1.41.5-1.51.2-1.51.4-1.6
Bone: apparent density0.00.10.40.3-0.10.10.2-0.20.00.20.20.6
Bone surface1.52.63.71.01.7-1.71.9-1.91.9-1.41.7-1.2
Bone volume0.91.52.20.71.2-1.21.5-1.51.3-1.11.4-0.8
Bone: connectivity density0.20.30.90.90.5-0.40.8-0.80.60.20.20.2
Bone: cortical apparent density0.91.23.1-1.7-1.21.2-1.01.0-1.10.20.11.2
Bone: cortical area0.81.32.00.11.2-1.11.1-1.11.4-1.21.4-0.9
Bone: cortical porosity0.60.62.21.50.8-0.80.6-0.60.70.2-0.4-0.8
Bone: cortical porosity0.40.42.01.40.6-0.50.4-0.40.30.3-0.6-0.6
Bone: cortical thickness0.10.10.3-0.2-0.40.4-0.50.5-0.30.4-0.20.6
Bone: cortical thickness0.10.10.50.70.3-0.2-0.20.20.20.2-0.3-0.3
Bone: cortical tissue density0.91.22.9-1.7-1.31.3-1.01.0-1.20.2-0.01.2
Bone: elastic displacement2.02.33.7-0.7-1.51.6-1.61.6-1.41.6-1.31.9
Bone: elastic work2.12.74.1-0.5-1.71.7-1.71.7-1.61.8-1.62.0
Bone: endosteal estimation1.94.26.10.01.9-2.02.2-2.22.1-2.42.5-2.0
Bone: endosteal perimeter2.75.56.80.62.3-2.42.6-2.62.4-2.62.5-2.4
Bone: final force0.10.10.3-0.10.4-0.20.3-0.30.5-0.20.50.1
Bone: final moment0.20.30.60.00.6-0.50.6-0.60.8-0.40.7-0.2
Bone: marrow area1.73.65.7-0.11.7-1.82.0-2.01.9-2.32.4-1.8
Bone: maximum diameter2.85.26.60.82.4-2.42.5-2.52.6-2.22.3-2.2
Bone: maximum force0.30.50.90.20.8-0.70.8-0.81.0-0.50.8-0.3
Bone: maximum moment0.50.81.40.31.0-0.91.0-1.01.2-0.71.0-0.5
Bone: minimum diameter1.22.25.5-1.01.0-1.11.3-1.31.3-2.22.3-1.0
Bone: periosteal estimation1.93.85.40.21.9-2.02.0-2.02.1-2.22.3-1.8
Bone: periosteal perimeter2.54.25.40.62.0-2.12.3-2.32.1-2.22.3-1.9
Bone: post-yield work0.60.91.40.41.0-0.91.2-1.21.2-0.71.0-0.5
Bone: stiffness0.10.20.9-1.00.00.1-0.00.00.2-0.40.70.3
Bone: tissue strength0.80.82.10.8-0.50.6-0.60.6-0.51.5-1.40.7
Bone: trabecular number0.60.92.5-0.1-1.01.0-0.70.7-0.81.2-0.71.6
Bone: trabecular spacing0.40.51.20.90.9-0.90.6-0.60.7-0.3-0.1-1.1
Bone: trabecular thickness0.10.10.4-0.5-0.30.20.2-0.2-0.0-0.30.60.4
Bone: trabecular tissue density0.91.25.4-2.3-1.00.9-1.01.0-0.8-0.50.60.7
Breakpoint value in progressive ratio session0.30.30.5-0.0-0.50.6-0.50.5-0.60.7-0.70.6
Distance traveled before self-admin0.30.40.8-0.9-0.60.7-0.60.6-0.40.3-0.20.8
Distance traveled after self-admin2.12.33.30.1-1.61.5-1.61.6-1.41.8-1.81.5
Delta time in closed arm before/after self-admin0.90.84.0-2.0-0.20.10.2-0.20.2-1.21.40.1
Delta time in open arm before/after self-admin2.62.53.11.11.6-1.81.7-1.71.7-1.41.3-1.7
Diff in mean of infusions in LGA sessions2.62.94.0-1.8-2.02.0-1.81.8-1.81.1-1.01.7
Extinction: sum of active levers before priming0.20.20.3-0.6-0.60.4-0.40.4-0.5-0.0-0.00.3
Active lever presses in extinction session 61.81.76.72.61.3-1.31.0-1.01.20.3-0.6-1.1
Delta distance traveled before/after self-admin0.20.31.11.0-0.20.1-0.10.1-0.20.7-0.80.1
Delta ambulatory time before/after self-admin0.40.51.51.2-0.30.2-0.30.3-0.41.0-1.20.1
Time in closed arm before self-admin1.01.27.32.70.7-0.70.3-0.30.30.8-1.0-0.6
Time in closed arm after self-admin1.01.11.80.5-0.91.0-1.01.0-1.11.3-1.31.0
Time in open arm before self-admin2.62.85.9-2.4-1.91.9-1.61.6-1.60.8-0.71.8
Time in open arm after self-admin1.21.42.7-1.00.8-0.91.2-1.21.2-1.51.6-0.8
Sum of active levers in priming session hrs 5-60.10.10.10.3-0.30.1-0.30.3-0.30.1-0.2-0.1
Time to tail flick, vehicle, before self-admin0.00.00.20.3-0.20.10.1-0.1-0.20.10.20.4
Time to tail flick, vehicle, after self-admin1.51.62.81.71.5-1.41.2-1.21.4-0.50.5-1.3
Time to tail flick, test, before self-admin0.40.40.7-0.40.5-0.50.6-0.60.6-0.90.9-0.4
Time to tail flick, test, after self-admin0.40.41.2-0.60.4-0.50.4-0.40.4-1.10.9-0.8
Delta time to tail flick, vehicle, before/after SA1.11.02.01.11.4-1.20.9-0.91.2-0.3-0.0-1.2
Delta time to tail flick, test, before/after SA0.40.30.5-0.4-0.60.6-0.70.7-0.70.4-0.60.3
Ambulatory time before self-admin0.80.81.2-0.7-0.91.0-0.90.9-0.80.9-0.81.1
Ambulatory time after self-admin2.83.15.00.5-1.71.7-1.81.8-1.72.2-2.21.6
Total heroin consumption0.10.10.30.50.2-0.30.2-0.20.4-0.10.0-0.4
Area under the delay curve0.00.00.2-0.40.1-0.00.1-0.10.1-0.20.1-0.2
Delay disc. indifference point, 0s delay0.60.61.30.50.9-0.80.8-0.80.7-0.80.5-1.2
Delay disc. indifference point, 16s delay0.20.20.3-0.2-0.30.4-0.40.4-0.40.5-0.50.4
Delay disc. indifference point, 2s delay0.91.01.7-0.11.2-1.01.0-1.00.9-1.00.7-1.3
Delay disc. indifference point, 24s delay0.80.71.3-0.8-1.11.0-0.80.8-0.80.6-0.41.1
Delay disc. indifference point, 4s delay0.50.51.6-0.20.7-0.60.3-0.30.3-1.10.6-1.3
Delay disc. indifference point, 8s delay0.30.30.40.10.6-0.50.6-0.60.7-0.40.4-0.5
Delay discount exponential model param0.00.00.20.5-0.0-0.10.0-0.00.00.1-0.00.1
Delay discount hyperbolic model param0.10.10.20.4-0.30.2-0.20.2-0.20.4-0.20.4
Fecal boli incidents, locomotor time 10.50.63.11.80.6-0.70.4-0.40.50.0-0.2-0.8
Change in fecal boli incidents, locomotor task1.31.21.9-1.1-1.11.3-1.11.1-1.20.9-0.81.4
Time >=10cm from walls, locomotor time 11.01.02.61.61.2-1.10.9-0.91.1-0.1-0.1-0.9
Bouts of movement, locomotor time 10.00.00.20.40.1-0.1-0.00.0-0.00.0-0.2-0.2
Total resting periods, locomotor time 10.20.20.50.7-0.20.2-0.40.4-0.40.6-0.70.3
Rest time, locomotor task time 10.91.01.50.3-1.00.9-1.21.2-1.21.0-1.20.5
Distance moved, locomotor task time 11.51.63.0-0.71.2-1.01.4-1.41.4-1.41.7-0.7
Vertical activity count, locomotor time 11.92.03.0-0.41.5-1.31.7-1.71.7-1.31.6-0.9
Time >=10cm from walls, locomotor time 20.70.81.51.01.0-1.00.8-0.80.8-0.80.5-1.2
Bouts of movement, locomotor time 20.50.50.7-0.30.8-0.70.7-0.70.6-0.80.7-0.8
Total resting periods, locomotor time 20.20.20.3-0.50.5-0.40.4-0.40.3-0.60.4-0.5
Rest time, locomotor task time 22.42.83.9-1.3-1.81.9-1.81.8-1.71.3-1.12.0
Distance moved, locomotor task time 23.23.85.41.02.1-2.22.1-2.12.0-1.91.6-2.3
Vertical activity count, locomotor time 22.93.14.30.21.8-1.82.1-2.11.9-1.81.8-1.8
Weight adjusted by age1.11.32.4-0.30.9-1.11.0-1.01.1-1.51.5-1.2
Seeking ratio, delayed vs. immediate footshock2.02.33.1-0.4-1.81.7-1.61.6-1.81.4-1.41.6
Locomotion in novel chamber0.60.83.92.00.8-0.80.5-0.50.90.3-0.3-0.6
Locomotion in novel chamber post-restriction1.72.04.62.11.6-1.51.4-1.41.50.1-0.3-1.3
Progressive ratio0.10.10.60.80.0-0.1-0.10.10.10.4-0.4-0.0
Food seeking constrained by brief footshock1.61.92.60.21.4-1.51.4-1.41.4-1.61.5-1.5
Seeking ratio, punishment vs. effort1.31.62.9-0.71.1-1.11.3-1.31.1-1.71.7-1.2
Run reversals in cocaine runway, females1.91.96.6-2.60.2-0.30.6-0.60.6-2.02.3-0.3
Run reversals in cocaine runway, males0.00.00.1-0.20.00.2-0.10.1-0.10.2-0.00.3
Latency to leave start box in cocaine runway2.12.25.3-2.3-1.61.6-1.61.6-1.50.6-0.71.3
Latency to leave start box in cocaine runway, F1.31.55.9-2.4-1.11.2-1.21.2-1.1-0.0-0.10.8
Latency to leave start box in cocaine runway, M0.50.50.9-0.1-0.70.7-0.70.7-0.61.0-0.90.8
Cd content in liver0.30.41.4-1.2-0.60.5-0.50.5-0.4-0.30.40.5
Co content in liver1.61.93.00.21.1-1.41.5-1.51.1-1.71.6-1.7
Cu content in liver0.70.92.0-0.10.7-0.90.8-0.80.7-1.41.1-1.3
Fe content in liver0.00.00.2-0.5-0.20.1-0.10.10.0-0.00.10.1
K content in liver0.10.10.4-0.6-0.30.20.0-0.0-0.3-0.30.30.0
Mg content in liver0.20.20.30.20.5-0.50.4-0.40.5-0.40.3-0.5
Mn content in liver2.22.63.5-0.0-1.51.6-1.71.7-1.71.9-1.91.5
Na content in liver0.20.20.40.60.5-0.40.5-0.50.30.0-0.3-0.7
Rb content in liver1.31.72.50.61.2-1.31.6-1.61.3-1.21.3-1.2
Se content in liver4.95.98.2-1.4-2.82.7-2.72.7-2.92.0-2.12.3
Sr content in liver0.20.20.40.5-0.20.2-0.30.3-0.30.6-0.70.1
Zn content in liver5.25.77.31.92.6-2.72.6-2.62.6-1.81.6-2.7