Hub : Genes

Cad

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000026474 0.19 0.16 1.1e-15 0.13 0.13 0.13 0.13 2.8e-14 3.1e-14 2.4e-14 2.2e-14
2 BLA gene expression ENSRNOG00000026474 0.05 0.05 6.0e-03 0.04 0.03 0.01 0.03 5.6e-03 1.2e-02 5.3e-02 1.4e-02
3 Brain mRNA stability ENSRNOG00000026474 0.47 0.24 0.0e+00 0.19 0.17 0.16 0.18 2.0e-17 3.3e-15 5.0e-15 1.9e-16
4 IL mRNA stability ENSRNOG00000026474 0.19 0.16 1.4e-03 0.05 0.08 0.08 0.06 2.8e-02 5.4e-03 6.8e-03 1.9e-02
5 LHb mRNA stability ENSRNOG00000026474 0.29 0.19 7.1e-06 0.2 0.23 0.24 0.23 1.4e-05 3.9e-06 2.2e-06 3.4e-06
6 Liver gene expression ENSRNOG00000026474 0.18 0.14 2.8e-16 0.13 0.13 0.13 0.13 3.0e-14 3.4e-14 1.5e-14 2.9e-14
7 Liver mRNA stability ENSRNOG00000026474 0.05 0.05 1.2e-04 0.03 0.03 0.03 0.03 4.7e-04 4.6e-04 3.3e-04 6.8e-04
8 NAcc mRNA stability ENSRNOG00000026474 0.2 0.17 7.9e-07 0.06 0.07 0.06 0.06 2.3e-05 5.9e-06 1.6e-05 4.1e-05
9 OFC mRNA stability ENSRNOG00000026474 0.18 0.14 1.4e-03 0.05 0.1 0.06 0.05 2.0e-02 2.9e-03 1.6e-02 2.2e-02
10 PL intron excision ratio chr6:25317224:25318594 0.04 0.04 2.9e-03 0.03 0.03 0.03 0.03 1.4e-03 2.5e-03 1.8e-03 2.1e-03
11 PL intron excision ratio chr6:25317224:25318919 0.04 0.04 2.8e-03 0.03 0.03 0.03 0.03 2.3e-03 3.3e-03 3.2e-03 3.9e-03
12 PL mRNA stability ENSRNOG00000026474 0.11 0.07 5.3e-10 0.1 0.13 0.11 0.11 5.1e-08 4.1e-10 9.6e-09 1.8e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.62.05.61.22.4-1.4-1.5-1.10.8-2.3-0.6-1.21.1-1.1-1.2
BMI without tail0.20.40.90.40.9-0.7-0.6-0.40.5-1.0-0.5-0.50.4-0.4-0.5
Body weight1.97.810.92.53.3-2.7-3.0-2.72.7-3.3-2.5-2.82.6-2.6-2.8
Epididymis fat weight13.832.143.35.45.7-5.4-5.9-5.65.4-6.6-5.6-5.85.3-5.3-5.8
Glucose0.10.20.30.60.6-0.5-0.5-0.40.5-0.4-0.5-0.50.3-0.3-0.5
Heart weight8.812.515.53.92.9-3.8-3.5-3.83.8-2.4-3.5-3.63.7-3.7-3.6
Left kidney weight0.00.10.80.2-0.3-0.1-0.0-0.30.40.9-0.4-0.20.4-0.4-0.2
Right kidney weight1.23.34.21.91.2-1.8-1.8-2.02.0-0.8-2.0-1.92.0-2.0-1.9
Tail length0.10.20.70.20.0-0.3-0.3-0.40.8-0.0-0.8-0.50.3-0.3-0.5
Length with tail1.34.86.92.01.7-2.1-2.2-2.32.6-1.7-2.5-2.32.2-2.2-2.3
Length without tail0.71.61.91.31.1-1.2-1.3-1.41.4-0.9-1.2-1.31.4-1.4-1.3
Liver weight, left1.42.23.41.31.8-1.4-1.5-1.61.6-1.0-1.3-1.51.6-1.6-1.5
Liver weight, right8.914.816.23.93.7-3.9-3.9-4.03.8-3.4-3.6-3.94.0-4.0-3.9
Parametrial fat weight6.412.514.13.53.6-3.6-3.7-3.73.3-3.8-2.9-3.53.7-3.7-3.5
Retroperitoneal fat weight20.868.992.98.28.1-8.2-8.8-8.37.6-9.6-7.7-8.48.0-8.0-8.4
Intraocular pressure6.18.69.82.92.9-2.9-3.1-2.92.8-2.8-2.8-3.03.1-3.1-2.9
Extensor digitorum longus weight4.216.718.3-4.2-4.04.24.14.1-4.23.54.34.2-4.04.04.2
Soleus weight3.710.911.9-3.4-2.93.43.43.3-3.33.53.43.4-3.13.13.4
Tibialis anterior weight3.211.113.8-3.4-3.23.33.23.3-3.72.33.73.4-3.43.43.4
Tibia length2.26.27.32.52.4-2.6-2.5-2.62.7-2.0-2.5-2.62.5-2.5-2.6
Number of licking bursts0.00.10.2-0.20.20.2-0.2-0.2-0.0-0.00.5-0.10.3-0.30.0
Food consumed during 24 hour testing period0.20.20.5-0.50.10.60.30.2-0.40.60.70.4-0.20.20.4
Times rat made contact with spout1.71.92.9-1.6-1.11.71.41.3-1.31.41.51.3-1.11.11.4
Mean time between licks in bursts2.83.85.12.01.9-1.9-1.9-2.02.0-1.3-1.9-2.02.3-2.3-1.9
Mean num. licks in bursts0.20.30.5-0.5-0.40.50.70.6-0.40.70.10.5-0.50.50.5
Std. dev. time between licks in bursts0.20.30.70.20.8-0.3-0.5-0.50.4-0.30.1-0.40.8-0.8-0.3
Water consumed over 24 hours1.11.32.9-1.5-0.31.31.11.0-1.21.21.71.2-0.70.71.3
Indifference point 0 sec0.40.72.40.70.9-0.6-0.9-0.70.5-1.6-0.6-0.70.8-0.8-0.8
Indifference point AUC2.22.64.5-1.8-1.11.71.51.6-1.81.02.11.7-1.51.51.7
Indifference point function ln k0.10.11.0-0.0-0.2-0.00.2-0.10.51.0-0.5-0.10.2-0.2-0.1
Indifference point function log k0.10.11.0-0.0-0.2-0.00.2-0.10.51.0-0.5-0.10.2-0.2-0.1
Delay discounting total patch changes 0 sec0.40.62.10.60.9-0.5-0.8-0.60.4-1.5-0.4-0.70.8-0.8-0.7
Delay discounting total patch changes 12 sec0.81.01.81.11.1-0.9-1.1-1.00.8-1.3-0.8-1.01.0-1.0-1.0
Delay discounting total patch changes 18 sec0.10.10.8-0.00.40.2-0.3-0.1-0.1-0.90.3-0.10.3-0.3-0.1
Delay discounting total patch changes 24 sec0.70.91.70.90.8-0.8-1.0-1.00.8-1.3-0.7-0.91.1-1.1-0.9
Delay discounting total patch changes 6 sec0.20.31.90.20.7-0.3-0.4-0.1-0.2-1.40.2-0.20.3-0.3-0.2
Delay discounting time to switch 0 sec0.00.10.50.3-0.1-0.4-0.2-0.0-0.2-0.7-0.1-0.10.0-0.0-0.1
Delay discounting water rate 0 sec0.10.10.4-0.5-0.20.60.30.10.20.60.00.2-0.20.20.1
Delay discounting water rate 12 sec1.32.03.11.50.2-1.4-1.4-1.61.7-1.2-1.8-1.51.2-1.2-1.6
Delay discounting water rate 18 sec0.50.71.60.80.1-0.9-0.6-0.91.20.2-1.2-0.80.7-0.7-0.9
Delay discounting water rate 24 sec1.72.43.91.50.9-1.4-1.6-1.71.8-1.5-2.0-1.71.3-1.3-1.7
Delay discounting water rate 6 sec1.21.73.41.40.3-1.3-1.1-1.51.8-0.2-1.7-1.41.4-1.4-1.4
Locomotor activity0.40.71.50.61.2-0.7-0.9-0.70.6-1.0-0.5-0.81.0-1.0-0.8
Locomotor testing distance0.10.10.4-0.20.00.30.00.3-0.6-0.70.40.2-0.20.20.2
Locomotor testing rearing0.91.42.0-1.3-1.11.41.01.4-1.3-0.11.01.1-1.41.41.1
Light reinforcement 13.46.210.4-2.4-1.62.42.42.5-3.11.53.22.6-2.42.42.7
Light reinforcement 23.24.26.3-1.8-1.51.82.12.0-2.42.12.52.2-1.91.92.2
Reaction time number correct0.40.60.8-0.8-0.70.90.80.7-0.90.70.90.8-0.70.70.8
Reaction time mean minus median0.00.00.1-0.1-0.10.10.10.10.10.1-0.20.0-0.20.2-0.0
Reaction time mean minus median AUC0.00.00.10.20.2-0.1-0.2-0.20.3-0.1-0.4-0.20.0-0.0-0.2
Reaction time num false alarms0.10.21.20.00.4-0.1-0.30.0-0.6-1.10.60.00.1-0.10.1
Reaction time num false alarms AUC0.10.20.9-0.00.6-0.1-0.30.0-0.7-0.90.70.10.2-0.20.1
Reaction time trials correct on left0.40.60.8-0.8-0.70.90.80.7-0.90.70.90.8-0.70.70.8
Reaction time trials on left0.50.70.9-0.8-0.70.90.90.8-0.90.70.90.8-0.80.80.9
Reaction time mean1.11.62.61.30.8-1.4-1.0-1.31.6-0.2-1.6-1.31.3-1.3-1.3
Reaction time mean AUC1.01.32.31.20.8-1.3-0.9-1.21.4-0.2-1.5-1.21.1-1.1-1.2
Median of all reaction times1.41.92.91.40.9-1.6-1.1-1.41.7-0.1-1.6-1.41.5-1.5-1.4
Reaction time omissions0.10.10.3-0.30.50.30.20.3-0.5-0.20.50.3-0.20.20.3
Reaction time false alarm rate0.30.41.60.40.9-0.5-0.7-0.4-0.2-1.30.2-0.40.5-0.5-0.3
Reaction time premature initiation rate0.20.30.60.50.4-0.6-0.5-0.50.5-0.5-0.5-0.50.8-0.8-0.5
Reaction time premature initiations0.00.00.1-0.0-0.1-0.1-0.0-0.1-0.0-0.10.0-0.00.3-0.3-0.0
Std. dev. reaction times0.30.30.70.50.3-0.6-0.5-0.60.8-0.2-0.8-0.60.5-0.5-0.7
Reaction time trials completed0.50.70.9-0.8-0.70.90.90.8-0.90.70.90.8-0.80.80.9
Reaction time trials AUC0.60.91.1-0.9-0.91.01.00.9-1.10.71.11.0-0.90.91.0
Social response proportion0.30.31.10.21.0-0.3-0.4-0.50.80.1-0.7-0.50.4-0.4-0.5
Social responses0.10.10.6-0.10.8-0.1-0.2-0.30.2-0.4-0.0-0.20.4-0.4-0.2
Social time0.20.20.80.20.6-0.3-0.4-0.60.90.1-0.6-0.50.4-0.4-0.5
Conditioned locomotion3.33.95.2-2.0-2.11.92.11.9-1.72.31.72.0-2.12.11.9
Cocaine response after cond. corrected0.60.61.4-0.90.10.90.80.7-0.81.21.00.8-0.40.40.9
Cocaine response after cond. not corrected1.31.53.0-1.3-0.51.31.31.2-1.21.71.41.2-0.90.91.3
Cocaine response before conditioning1.51.83.8-1.2-2.01.21.41.3-1.11.51.01.3-1.41.41.3
Saline control response0.71.01.3-1.1-1.10.91.00.9-0.81.11.01.0-0.90.91.0
Condit. Reinf. active minus inactive responses4.05.06.1-2.2-2.52.12.22.4-2.51.42.12.3-2.42.42.2
Condit. Reinf. active-inactive response ratio1.01.01.2-0.9-0.91.01.11.1-1.01.00.91.0-1.11.11.0
Condit. Reinf. active responses3.34.56.0-2.1-2.42.02.12.3-2.51.02.02.2-2.32.32.1
Condit. Reinf. inactive responses1.72.13.2-1.5-1.71.51.41.5-1.80.41.51.5-1.51.51.5
Condit. Reinf. lever presses2.02.74.2-1.7-2.01.61.71.5-1.71.41.51.6-1.61.61.6
Condit. Reinf. lever reinforcers received3.04.25.7-2.0-2.41.92.02.2-2.30.91.92.1-2.32.32.0
Pavlov. Cond. lever latency1.72.32.81.71.4-1.5-1.6-1.41.5-1.5-1.5-1.51.6-1.6-1.5
Pavlov. Cond. magazine entry latency0.30.40.7-0.7-0.80.60.60.5-0.60.50.80.6-0.40.40.7
Pavlov. Cond. change in total contacts0.60.81.1-1.1-1.01.00.90.8-0.90.91.00.9-0.80.80.9
Pavlov. Cond. index score1.11.52.0-1.4-1.41.21.21.1-1.11.21.31.2-1.11.11.2
Pavlov. Cond. latency score1.21.52.1-1.4-1.51.21.21.1-1.11.31.31.2-1.11.11.2
Pavlov. Cond. lever contacts0.71.01.4-1.2-1.11.01.00.9-1.01.01.11.0-0.90.91.0
Pavlov. Cond. magazine entry number0.10.10.30.50.4-0.4-0.3-0.30.4-0.4-0.6-0.40.1-0.1-0.4
Pavlov. Cond. intertrial magazine entries3.54.56.52.11.9-2.2-2.2-2.01.9-2.6-2.2-2.12.0-2.0-2.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.5-1.2-1.21.11.00.9-0.91.01.11.0-0.90.91.0
Pavlov. Cond. response bias1.52.02.5-1.6-1.41.41.51.3-1.41.51.51.4-1.31.31.5
Conditioned reinforcement - actives1.81.82.6-1.4-1.51.41.41.3-0.71.60.91.3-1.41.41.2
Conditioned reinforcement - inactives3.53.97.8-1.8-2.01.72.11.9-1.92.81.92.0-1.81.82.0
Conditioned locomotion0.70.81.4-1.1-1.21.01.00.9-0.20.80.10.8-1.21.20.6
Intermittent access intake day 1-15 change0.30.31.3-0.5-0.70.30.60.3-0.01.10.40.4-0.20.20.5
Intermittent access intake escalation0.10.10.6-0.3-0.40.10.30.10.20.80.20.20.1-0.10.2
Intermittent access intake escalation 20.20.20.40.50.3-0.6-0.3-0.50.4-0.00.0-0.30.6-0.6-0.3
Intermitt. access day 1 inactive lever presses0.20.20.4-0.4-0.70.30.50.4-0.70.60.60.5-0.40.40.5
Intermitt. access day 15 inactive lever presses8.99.914.0-3.1-2.83.03.13.1-3.52.43.73.3-3.13.13.3
Intermitt. access escalation Index0.30.31.00.40.8-0.3-0.6-0.40.0-1.00.3-0.30.5-0.5-0.3
Intermittent access day 1 total infusions5.76.57.2-2.4-2.52.42.62.5-2.62.72.52.6-2.62.62.6
Intermittent access day 15 total infusions2.83.15.9-1.6-1.91.51.91.6-1.52.41.71.8-1.51.51.8
Intermittent access terminal intake (last 3 days)2.42.75.3-1.5-1.81.41.81.5-1.42.31.51.7-1.41.41.7
Intermittent access total infusions2.73.05.8-1.7-1.81.61.81.6-1.42.41.31.7-1.61.61.7
Intermittent access day 1 locomotion2.42.42.8-1.5-1.61.31.61.5-1.61.71.51.6-1.61.61.6
Intermittent access day 15 total locomotion0.80.91.0-1.0-1.00.81.00.9-1.00.91.01.0-0.90.91.0
Intermittent access total locomotion0.40.50.7-0.8-0.80.60.70.7-0.70.70.50.7-0.80.80.7
Intermittent access standard deviation0.30.30.5-0.5-0.70.60.60.5-0.60.40.50.5-0.50.50.5
Cocaine induced anxiety0.40.50.9-0.7-0.60.60.70.7-0.80.70.90.8-0.60.60.8
Post-drug Anxiety1.01.11.71.11.2-1.3-1.0-1.10.9-0.7-0.6-1.01.3-1.3-0.9
Baseline Anxiety1.92.02.31.51.5-1.5-1.4-1.41.4-1.3-1.4-1.41.4-1.4-1.4
Lifetime Intake3.74.26.9-2.1-2.12.02.22.0-1.72.61.72.0-2.02.02.0
Incentive Sensitization - Responses0.10.10.70.20.1-0.4-0.0-0.20.50.8-0.3-0.10.3-0.3-0.2
Incentive Sensitization - Breakpoint0.20.20.40.40.2-0.6-0.2-0.40.60.6-0.4-0.30.5-0.5-0.3
Progressive ratio test 1 active lever presses2.12.22.7-1.5-1.41.51.61.5-1.31.61.21.5-1.61.61.4
Progressive ratio test 1 breakpoint1.91.92.3-1.4-1.31.41.41.4-1.31.41.11.4-1.51.51.3
Progressive ratio test 1 inactive lever presses5.45.86.7-2.4-2.62.42.52.4-2.22.42.12.4-2.62.62.3
Progressive ratio test 2 active lever presses0.20.21.3-0.5-0.50.30.50.4-0.11.20.10.4-0.40.40.4
Progressive ratio test 2 breakpoint0.30.31.4-0.6-0.70.40.60.5-0.21.20.20.5-0.50.50.4
Progressive ratio test 2 inactive lever presses2.83.23.8-1.7-1.91.61.91.7-1.72.01.81.8-1.81.81.8
Total sessions with >9 infusions3.33.64.5-2.0-1.92.12.02.0-1.52.11.31.8-2.12.11.7
Short access day 1 total inactive lever presses5.25.76.9-2.3-2.32.22.52.3-2.62.62.62.5-2.22.22.5
Short access day 10 total inactive lever presses1.11.22.6-1.0-1.00.91.01.0-1.60.31.41.1-1.21.21.2
Short access day 1 total infusions5.96.37.1-2.6-2.42.72.52.6-2.42.32.32.5-2.72.72.5
Short access day 10 total infusions4.54.98.3-2.2-2.22.22.42.2-1.92.91.92.3-2.12.12.2
Short access total infusions3.74.15.7-2.1-2.02.12.12.1-1.72.41.62.0-2.12.12.0
Short access day 1 locomotion8.08.59.9-3.0-3.23.03.03.0-2.82.52.62.9-3.13.12.8
Short access day 10 total locomotion0.91.01.6-0.9-1.30.81.10.9-1.01.20.91.0-1.01.01.0
Short access total locomotion1.01.02.1-0.9-1.20.91.10.9-0.71.40.61.0-1.01.00.9
Compulsive drug intake0.90.91.90.91.3-0.8-1.1-0.80.6-1.4-0.4-0.91.0-1.0-0.8
One hour access (0.3 mA shock)1.92.23.7-1.6-1.41.41.51.4-1.31.91.51.5-1.31.31.5
One hour access (shock baseline)2.42.85.4-1.8-1.81.61.81.6-1.22.31.21.6-1.61.61.6
Number of responses in last shaping day0.70.71.0-1.0-0.90.91.00.9-0.61.00.50.8-0.90.90.8
Context. condit. distance diff. score0.00.00.00.00.0-0.10.0-0.10.20.2-0.2-0.10.2-0.2-0.1
Locomotion velocity, session 10.10.10.60.20.8-0.2-0.3-0.2-0.1-0.60.3-0.10.2-0.2-0.1
Locomotion distance, session 11.51.93.6-1.5-1.21.41.31.2-1.61.01.91.4-1.11.11.5
Locomotion velocity, session 20.30.30.50.50.4-0.6-0.5-0.60.6-0.3-0.5-0.60.7-0.7-0.5
Locomotion distance, session 20.00.00.2-0.0-0.1-0.0-0.1-0.1-0.2-0.40.30.0-0.00.00.0
Locomotion velocity, session 30.91.01.7-0.8-1.30.90.91.0-1.10.10.90.9-1.31.30.9
Locomotion distance, session 30.90.91.7-0.9-0.90.90.81.0-1.20.11.31.0-1.01.01.0
Stereotopy head waving bouts, day 32.02.43.1-1.5-1.41.51.71.6-1.51.41.31.6-1.81.81.6
Stereotopy head waving duration, day 30.20.30.5-0.5-0.40.50.60.5-0.40.50.20.5-0.70.70.4
Locomotion velocity, session 71.11.21.9-1.2-0.71.21.01.0-1.30.31.41.1-1.11.11.1
Locomotion distance, session 70.10.10.6-0.40.00.3-0.00.1-0.5-0.70.80.2-0.10.10.2
Stereotopy head waving bouts, day 70.00.00.10.20.1-0.2-0.1-0.10.1-0.1-0.3-0.10.1-0.1-0.1
Stereotopy head waving duration, day 70.40.50.6-0.7-0.70.70.80.7-0.60.60.40.7-0.80.80.7
Locomotion velocity, session 80.30.40.9-0.8-0.60.70.60.5-0.31.00.50.6-0.40.40.6
Locomotion distance, session 80.20.40.6-0.8-0.50.70.60.4-0.50.80.80.6-0.30.30.6
Degree of sensitization distance0.80.91.10.71.0-0.8-1.0-1.00.9-0.9-0.8-0.91.1-1.1-0.9
Degree of sensitization stereotypy0.20.20.30.50.5-0.5-0.5-0.50.4-0.5-0.5-0.50.5-0.5-0.5
Condit. Reinf. active minus inactive responses0.80.92.00.91.2-0.8-1.0-0.80.6-1.4-0.7-0.90.9-0.9-0.9
Condit. Reinf. active-inactive response ratio0.80.81.91.00.9-0.9-1.0-0.80.6-1.4-0.8-0.90.7-0.7-0.9
Condit. Reinf. active responses0.10.10.3-0.30.30.40.20.3-0.6-0.10.50.3-0.20.20.3
Condit. Reinf. inactive responses1.31.62.2-1.4-0.71.31.31.2-1.41.31.51.3-1.11.11.3
Incentive salience index mean0.00.00.20.00.50.2-0.10.1-0.3-0.40.20.00.0-0.00.0
Condit. Reinf. lever presses0.40.50.8-0.7-0.10.80.70.7-0.80.90.80.7-0.60.60.8
Time in familiar zone, hab. session 10.70.71.30.71.1-0.7-0.9-0.90.8-0.8-0.6-0.80.9-0.9-0.8
Time in novel zone, hab. session 10.50.51.30.8-0.0-0.8-0.6-0.50.5-1.1-1.0-0.70.2-0.2-0.7
Total zone transitions, hab. session 10.10.10.3-0.4-0.40.40.30.1-0.20.60.40.3-0.20.20.3
Total locomotion distance, hab. session 10.20.31.1-0.7-0.40.60.60.3-0.31.00.40.4-0.50.50.5
Locomotion velocity, hab. session 11.01.43.1-1.2-1.01.21.31.0-1.01.81.11.1-1.01.01.2
Time in familiar zone, hab. session 20.00.00.1-0.20.00.2-0.0-0.0-0.1-0.10.40.10.2-0.20.1
Time in novel zone, hab. session 20.40.41.00.80.5-0.8-0.6-0.50.7-0.7-1.0-0.70.4-0.4-0.7
Total zone transitions, hab. session 20.10.10.3-0.4-0.20.40.00.1-0.4-0.40.60.2-0.00.00.2
Total locomotion distance, hab. session 20.20.20.6-0.6-0.30.60.30.3-0.60.10.80.4-0.20.20.5
Locomotion velocity, hab. session 20.30.40.9-0.8-0.50.80.50.5-0.80.21.00.6-0.40.40.7
Novel to familiar place preference ratio1.21.21.41.21.1-1.2-1.0-1.11.0-1.0-1.2-1.11.1-1.1-1.1
Novelty place preference1.81.92.21.51.3-1.4-1.3-1.31.3-1.3-1.5-1.41.3-1.3-1.4
Time in novel zone, NPP test2.02.12.61.61.3-1.5-1.4-1.41.3-1.4-1.6-1.51.4-1.4-1.5
Total zone transitions, NPP test1.31.92.4-1.4-1.51.41.31.3-1.51.11.61.4-1.31.31.4
Total locomotion distance, NPP test1.92.73.1-1.6-1.61.61.61.6-1.71.31.71.6-1.81.81.7
Locomotion velocity, NPP test3.04.35.0-2.1-2.02.12.12.0-2.11.82.22.1-2.12.12.1
Pavlov. Cond. lever latency1.51.93.11.41.2-1.5-1.3-1.31.6-1.1-1.8-1.41.3-1.3-1.5
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.20.20.00.1-0.2-0.10.40.1-0.10.10.2
Pavlov. Cond. change in total contacts0.00.00.1-0.1-0.10.20.10.1-0.20.10.30.1-0.10.10.2
Pavlov. Cond. index score0.60.71.6-0.9-0.70.90.70.8-1.00.61.30.9-0.60.60.9
Pavlov. Cond. latency score0.50.71.7-0.8-0.70.90.70.7-1.00.41.30.9-0.60.60.9
Pavlov. Cond. lever contacts0.91.01.6-1.0-0.91.11.00.9-1.11.01.31.0-0.90.91.1
Pavlov. Cond. magazine entry number0.40.51.10.70.6-0.7-0.6-0.60.9-0.3-1.0-0.70.6-0.6-0.7
Pavlov. Cond. intertrial magazine entries1.21.42.6-1.1-1.01.11.31.2-1.11.60.91.2-1.21.21.2
Pavlov. Cond. lever-magazine prob. diff.1.31.62.7-1.3-1.21.41.21.2-1.41.01.61.3-1.11.11.4
Pavlov. Cond. response bias1.41.72.1-1.3-1.31.31.31.2-1.41.21.51.3-1.31.31.3
Bone: apparent density4.87.99.4-2.9-2.42.82.92.7-2.82.93.12.9-2.62.62.9
Bone surface2.34.06.5-2.2-1.62.21.91.8-2.11.92.62.1-1.71.72.1
Bone volume2.54.25.8-2.2-1.62.22.11.9-2.02.32.42.1-1.81.82.2
Bone: connectivity density4.57.19.2-2.8-2.42.72.62.6-2.82.33.02.7-2.52.52.8
Bone: cortical apparent density0.30.41.3-0.7-1.10.60.50.5-0.60.60.70.6-0.50.50.6
Bone: cortical area0.20.31.0-0.7-0.20.70.40.4-0.60.31.00.5-0.20.20.6
Bone: cortical porosity1.82.03.1-1.3-1.51.31.61.4-1.01.81.01.4-1.51.51.3
Bone: cortical porosity1.41.52.9-1.2-1.11.11.41.3-0.91.70.91.3-1.31.31.2
Bone: cortical thickness0.10.20.50.30.5-0.2-0.4-0.50.4-0.1-0.0-0.40.7-0.7-0.3
Bone: cortical thickness1.31.52.1-1.3-1.21.41.21.2-1.21.21.51.3-0.90.91.3
Bone: cortical tissue density0.20.31.0-0.6-1.00.50.40.4-0.50.50.60.5-0.40.40.5
Bone: elastic displacement0.91.01.5-0.9-1.01.01.11.1-0.91.20.61.0-1.01.00.9
Bone: elastic work0.91.21.5-1.1-0.81.21.11.2-1.21.01.01.1-1.11.11.1
Bone: endosteal estimation0.40.81.5-1.1-0.71.10.80.9-1.10.41.20.9-0.70.70.9
Bone: endosteal perimeter0.10.20.6-0.6-0.20.60.40.4-0.60.10.80.5-0.30.30.5
Bone: final force0.10.20.5-0.6-0.30.60.30.2-0.30.30.70.3-0.20.20.4
Bone: final moment0.10.20.5-0.6-0.30.60.30.2-0.40.30.70.4-0.30.30.4
Bone: marrow area0.40.91.5-1.1-0.71.10.80.9-1.10.41.20.9-0.80.81.0
Bone: maximum diameter0.71.22.6-1.3-0.71.20.91.0-1.40.51.61.1-0.90.91.2
Bone: maximum force0.00.00.1-0.3-0.00.30.0-0.0-0.10.10.40.1-0.10.10.1
Bone: maximum moment0.00.10.2-0.4-0.10.40.10.1-0.20.20.50.2-0.20.20.2
Bone: minimum diameter0.10.31.00.20.7-0.2-0.6-0.50.2-1.00.0-0.40.6-0.6-0.4
Bone: periosteal estimation0.51.02.1-1.2-0.71.20.90.9-1.10.71.41.0-0.70.71.1
Bone: periosteal perimeter0.10.20.6-0.6-0.10.60.30.3-0.50.30.80.4-0.20.20.5
Bone: post-yield work0.50.71.8-0.9-0.80.90.90.8-0.51.30.70.8-0.70.70.8
Bone: stiffness0.00.00.10.00.2-0.1-0.3-0.30.2-0.30.1-0.20.1-0.1-0.2
Bone: tissue strength1.01.01.31.01.1-1.1-0.9-1.01.0-0.6-1.1-1.00.9-0.9-1.0
Bone: trabecular number3.75.77.1-2.4-1.92.42.42.4-2.42.72.62.5-2.22.22.5
Bone: trabecular spacing3.34.35.62.31.9-2.3-2.0-2.02.1-1.8-2.4-2.11.8-1.8-2.1
Bone: trabecular thickness0.81.01.4-1.2-0.81.11.00.9-0.91.01.01.0-1.01.01.0
Bone: trabecular tissue density0.30.41.5-0.6-1.20.40.60.5-0.40.80.50.6-0.80.80.5
Breakpoint value in progressive ratio session1.11.22.0-1.4-0.71.41.01.3-1.00.81.01.1-1.11.11.1
Distance traveled before self-admin0.10.10.7-0.1-0.20.10.2-0.10.30.8-0.10.00.2-0.20.0
Distance traveled after self-admin1.01.21.91.11.2-1.0-1.0-1.11.2-0.5-0.9-1.01.4-1.4-1.0
Delta time in closed arm before/after self-admin0.10.10.20.10.5-0.1-0.4-0.20.2-0.30.0-0.20.5-0.5-0.2
Delta time in open arm before/after self-admin0.50.40.9-0.5-0.50.60.60.6-0.90.00.60.6-1.01.00.6
Diff in mean of infusions in LGA sessions0.20.30.6-0.7-0.10.80.40.5-0.60.10.50.5-0.50.50.5
Extinction: sum of active levers before priming0.30.30.6-0.6-0.50.60.50.5-0.80.20.60.6-0.60.60.6
Active lever presses in extinction session 60.70.71.1-1.0-0.71.00.81.0-0.60.60.50.8-0.90.90.8
Delta distance traveled before/after self-admin1.41.52.21.31.4-1.2-1.3-1.21.1-1.5-0.9-1.21.3-1.3-1.2
Delta ambulatory time before/after self-admin0.30.30.60.50.8-0.5-0.6-0.50.4-0.7-0.3-0.50.7-0.7-0.5
Time in closed arm before self-admin0.40.40.70.40.6-0.4-0.7-0.60.8-0.7-0.7-0.70.8-0.8-0.7
Time in closed arm after self-admin1.31.31.80.91.1-0.9-1.2-1.01.3-1.2-1.3-1.21.2-1.2-1.2
Time in open arm before self-admin0.10.10.20.40.0-0.4-0.1-0.20.00.5-0.0-0.10.2-0.2-0.1
Time in open arm after self-admin1.61.82.8-1.0-1.21.01.31.3-1.71.21.61.4-1.31.31.4
Sum of active levers in priming session hrs 5-60.50.51.5-0.6-0.30.60.60.7-1.2-0.01.20.8-0.50.50.8
Time to tail flick, vehicle, before self-admin2.02.13.11.51.1-1.4-1.5-1.41.6-1.4-1.7-1.51.2-1.2-1.6
Time to tail flick, vehicle, after self-admin3.94.15.51.72.2-1.7-2.1-2.02.0-2.3-2.2-2.11.8-1.8-2.2
Time to tail flick, test, before self-admin0.60.61.3-0.7-0.90.70.80.8-0.61.10.60.8-0.80.80.8
Time to tail flick, test, after self-admin0.10.10.40.20.0-0.1-0.1-0.30.60.6-0.5-0.30.2-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.10.60.1-0.2-0.1-0.1-0.70.1-0.10.1-0.1-0.1
Delta time to tail flick, test, before/after SA0.40.31.1-0.5-0.60.60.70.4-0.41.00.50.5-0.50.50.6
Ambulatory time before self-admin0.10.10.6-0.2-0.50.20.30.1-0.10.80.20.2-0.00.00.2
Ambulatory time after self-admin0.70.71.30.90.7-0.9-0.7-0.91.0-0.3-0.7-0.81.1-1.1-0.8
Total heroin consumption2.42.93.4-1.8-1.51.81.71.7-1.81.61.81.7-1.61.61.8
Area under the delay curve0.00.00.3-0.10.5-0.1-0.1-0.10.10.2-0.1-0.10.2-0.2-0.1
Delay disc. indifference point, 0s delay4.04.36.01.92.4-2.0-2.0-2.12.2-1.0-2.0-2.12.4-2.4-2.0
Delay disc. indifference point, 16s delay0.10.10.2-0.3-0.20.10.20.2-0.40.10.30.2-0.30.30.3
Delay disc. indifference point, 2s delay0.40.40.70.50.7-0.5-0.5-0.70.7-0.1-0.6-0.60.8-0.8-0.6
Delay disc. indifference point, 24s delay0.80.72.1-1.0-0.80.81.00.9-0.71.50.50.8-0.60.60.8
Delay disc. indifference point, 4s delay0.00.10.4-0.00.6-0.1-0.1-0.20.10.10.1-0.10.2-0.2-0.0
Delay disc. indifference point, 8s delay0.00.00.2-0.30.20.10.10.00.00.4-0.10.00.0-0.00.0
Delay discount exponential model param0.10.10.20.4-0.2-0.2-0.2-0.20.2-0.5-0.2-0.20.1-0.1-0.2
Delay discount hyperbolic model param0.10.10.20.4-0.2-0.3-0.2-0.20.2-0.5-0.3-0.20.1-0.1-0.3
Fecal boli incidents, locomotor time 10.30.41.0-0.4-0.90.40.70.5-0.51.00.30.6-0.60.60.5
Change in fecal boli incidents, locomotor task4.74.56.11.92.5-2.0-2.2-2.02.1-1.9-2.1-2.12.2-2.2-2.1
Time >=10cm from walls, locomotor time 10.10.10.40.10.1-0.2-0.2-0.30.40.2-0.6-0.30.1-0.1-0.3
Bouts of movement, locomotor time 12.02.23.4-1.8-1.41.51.41.4-1.80.71.81.5-1.31.31.6
Total resting periods, locomotor time 12.32.64.0-1.9-1.51.61.61.6-2.00.72.01.7-1.41.41.7
Rest time, locomotor task time 10.10.10.2-0.3-0.40.30.40.3-0.30.10.20.3-0.20.20.3
Distance moved, locomotor task time 11.21.31.71.21.2-1.2-1.2-1.21.3-0.5-1.3-1.20.9-0.9-1.2
Vertical activity count, locomotor time 10.60.60.90.80.9-0.9-0.8-0.90.9-0.2-0.8-0.80.7-0.7-0.8
Time >=10cm from walls, locomotor time 20.30.30.9-0.8-0.50.60.60.4-0.10.90.20.4-0.40.40.4
Bouts of movement, locomotor time 20.20.20.60.20.1-0.5-0.4-0.50.3-0.5-0.1-0.40.7-0.7-0.4
Total resting periods, locomotor time 20.10.10.2-0.1-0.1-0.2-0.1-0.2-0.1-0.40.3-0.10.5-0.5-0.0
Rest time, locomotor task time 21.11.22.1-1.1-1.01.11.11.2-1.40.71.41.2-0.70.71.3
Distance moved, locomotor task time 20.70.81.60.81.0-0.9-0.9-1.01.2-0.3-1.2-1.00.5-0.5-1.0
Vertical activity count, locomotor time 20.30.30.80.30.6-0.4-0.5-0.60.90.1-0.9-0.60.3-0.3-0.6
Weight adjusted by age0.10.10.2-0.2-0.30.30.10.2-0.4-0.40.20.1-0.30.30.1
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.0-0.1-0.00.10.1-0.1-0.40.20.1-0.20.20.1
Locomotion in novel chamber0.80.91.71.00.8-1.0-1.0-0.91.1-1.3-1.1-1.00.5-0.5-1.1
Locomotion in novel chamber post-restriction2.32.76.21.61.6-1.5-1.8-1.51.3-2.5-1.6-1.61.3-1.3-1.7
Progressive ratio0.10.10.3-0.5-0.30.50.30.4-0.4-0.10.20.3-0.50.50.3
Food seeking constrained by brief footshock5.46.68.8-2.4-3.02.52.72.6-2.12.71.82.5-2.92.92.4
Seeking ratio, punishment vs. effort0.50.61.6-0.5-0.90.60.80.6-0.51.30.60.7-0.70.70.7
Run reversals in cocaine runway, females0.20.20.50.5-0.1-0.4-0.2-0.40.60.6-0.7-0.40.4-0.4-0.4
Run reversals in cocaine runway, males0.20.20.6-0.2-0.70.40.50.3-0.30.80.00.3-0.60.60.3
Latency to leave start box in cocaine runway0.60.71.3-0.8-0.70.70.90.8-0.51.10.60.8-0.90.90.8
Latency to leave start box in cocaine runway, F0.50.60.7-0.7-0.50.70.80.8-0.80.80.80.8-0.80.80.8
Latency to leave start box in cocaine runway, M1.01.01.5-0.9-1.11.01.11.0-0.41.20.60.9-1.21.20.9
Cd content in liver0.10.10.4-0.10.40.0-0.2-0.0-0.2-0.70.3-0.00.1-0.10.0
Co content in liver5.05.87.8-2.5-2.12.62.62.4-2.32.82.32.5-2.22.22.5
Cu content in liver0.00.00.1-0.3-0.10.20.10.3-0.3-0.10.30.2-0.20.20.2
Fe content in liver0.00.00.20.0-0.4-0.0-0.00.2-0.1-0.30.00.1-0.20.20.0
K content in liver0.30.30.80.20.9-0.3-0.6-0.50.1-0.90.2-0.40.7-0.7-0.3
Mg content in liver0.50.51.40.41.2-0.5-0.8-0.60.2-1.20.1-0.50.8-0.8-0.5
Mn content in liver0.60.71.4-0.8-0.81.00.60.8-1.2-0.41.10.8-0.80.80.8
Na content in liver0.50.51.8-0.7-0.30.60.80.7-0.51.30.70.7-0.40.40.8
Rb content in liver0.10.10.90.00.3-0.2-0.30.0-0.2-0.90.2-0.10.1-0.1-0.1
Se content in liver0.30.42.10.30.4-0.5-0.7-0.50.3-1.4-0.2-0.50.6-0.6-0.5
Sr content in liver0.30.31.20.41.1-0.4-0.4-0.50.50.1-0.4-0.50.6-0.6-0.4
Zn content in liver1.51.62.60.91.4-1.1-1.4-1.31.1-1.6-1.0-1.31.3-1.3-1.3