Togaram2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000026344 0.16 0.12 6.9e-09 0.07 0.08 0.07 0.07 2.9e-08 7.6e-09 1.5e-08 1.6e-08
2 BLA intron excision ratio chr6:23816601:23828169 0.24 0.19 1.8e-07 0.11 0.11 0.11 0.11 1.7e-06 1.4e-06 2.8e-06 1.5e-06
3 Brain intron excision ratio chr6:23816601:23828169 0.17 0.1 0.0e+00 0.21 0.19 0.19 0.2 7.9e-19 9.0e-18 8.9e-18 5.1e-18
4 Brain intron excision ratio chr6:23816601:23828284 0.16 0.09 0.0e+00 0.2 0.18 0.18 0.18 1.5e-18 1.4e-16 1.2e-16 1.2e-16
5 Liver gene expression ENSRNOG00000026344 0.14 0.11 1.4e-10 0.09 0.08 0.08 0.08 8.5e-10 3.4e-09 3.8e-09 2.0e-09
6 Liver intron excision ratio chr6:23786077:23786825 0.03 0.03 2.7e-03 0.02 0.02 0.01 0.02 1.4e-03 3.5e-03 4.0e-02 2.8e-03
7 Liver mRNA stability ENSRNOG00000026344 0.05 0.04 4.0e-05 0.04 0.04 0.04 0.04 2.1e-05 3.0e-05 4.7e-05 4.3e-05
8 NAcc gene expression ENSRNOG00000026344 0.08 0.06 7.1e-06 0.07 0.06 0.07 0.06 1.2e-05 2.4e-05 1.2e-05 2.1e-05
9 NAcc intron excision ratio chr6:23816601:23828169 0.14 0.11 2.3e-09 0.14 0.13 0.14 0.13 9.3e-11 1.3e-09 2.6e-10 4.8e-10
10 NAcc intron excision ratio chr6:23816601:23828284 0.14 0.11 4.0e-09 0.14 0.12 0.13 0.13 2.6e-10 2.2e-09 6.4e-10 1.0e-09
11 OFC gene expression ENSRNOG00000026344 0.31 0.19 4.9e-06 0.19 0.23 0.21 0.2 2.9e-05 3.6e-06 9.1e-06 2.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.30.91.5-1.0-0.8-0.60.6-1.00.91.11.2-0.90.9-1.0
BMI without tail0.10.10.5-0.4-0.2-0.00.0-0.50.10.70.4-0.30.3-0.5
Body weight1.66.67.3-2.6-2.6-2.42.4-2.42.62.62.6-2.62.6-2.7
Epididymis fat weight15.235.437.1-5.9-6.0-5.95.9-6.06.05.85.7-6.16.1-6.1
Glucose0.60.81.2-0.8-0.9-0.80.8-1.10.70.80.9-1.11.1-0.9
Heart weight9.914.215.6-3.8-3.8-4.04.0-3.53.93.73.7-3.63.6-3.8
Left kidney weight0.00.10.70.20.0-0.10.10.80.1-0.6-0.10.0-0.00.2
Right kidney weight0.71.93.0-1.3-1.5-1.61.6-0.71.70.91.4-1.31.3-1.2
Tail length0.20.50.7-0.7-0.9-0.70.7-0.60.50.70.5-0.80.8-0.8
Length with tail1.45.36.3-2.2-2.5-2.42.4-2.12.32.22.0-2.42.4-2.4
Length without tail1.02.12.9-1.3-1.6-1.61.6-1.31.71.21.3-1.51.5-1.4
Liver weight, left2.43.84.5-1.9-2.1-2.12.1-1.82.11.51.9-2.12.1-1.8
Liver weight, right9.816.218.0-4.0-4.1-4.24.2-3.94.23.93.7-4.04.0-4.1
Parametrial fat weight5.110.012.6-3.3-3.0-2.82.8-3.42.93.53.5-3.13.1-3.3
Retroperitoneal fat weight21.370.673.3-8.5-8.4-8.28.2-8.48.38.68.4-8.58.5-8.6
Intraocular pressure2.94.04.9-1.8-2.1-2.12.1-1.92.22.11.6-2.02.0-2.1
Extensor digitorum longus weight4.919.520.34.54.54.4-4.44.4-4.3-4.2-4.34.5-4.54.5
Soleus weight5.816.818.14.24.24.1-4.14.0-4.0-3.8-4.04.3-4.34.1
Tibialis anterior weight4.315.016.03.84.04.0-4.03.8-3.9-3.5-3.74.0-4.03.9
Tibia length2.67.48.2-2.5-2.8-2.72.7-2.82.72.92.3-2.82.8-2.9
Number of licking bursts0.20.30.50.70.50.5-0.50.3-0.7-0.5-0.60.4-0.40.5
Food consumed during 24 hour testing period0.20.20.50.40.50.4-0.40.7-0.5-0.5-0.10.5-0.50.5
Times rat made contact with spout2.63.04.22.01.71.6-1.61.6-1.7-1.7-2.11.6-1.61.7
Mean time between licks in bursts2.63.64.4-2.1-1.9-1.81.8-1.91.81.71.9-2.02.0-1.9
Mean num. licks in bursts0.10.20.20.40.40.4-0.40.5-0.2-0.3-0.50.4-0.40.4
Std. dev. time between licks in bursts0.00.00.2-0.1-0.1-0.10.1-0.5-0.10.30.0-0.20.2-0.2
Water consumed over 24 hours1.11.21.91.21.00.9-0.91.4-0.9-1.3-1.21.1-1.11.2
Indifference point 0 sec0.20.30.4-0.4-0.5-0.60.6-0.60.50.60.1-0.50.5-0.6
Indifference point AUC1.51.72.61.41.41.5-1.51.0-1.6-0.9-1.21.3-1.31.3
Indifference point function ln k0.10.10.2-0.3-0.3-0.40.4-0.00.5-0.20.4-0.20.2-0.1
Indifference point function log k0.10.10.2-0.3-0.3-0.40.4-0.00.5-0.20.4-0.20.2-0.1
Delay discounting total patch changes 0 sec0.10.10.3-0.3-0.3-0.40.4-0.40.40.50.0-0.30.3-0.4
Delay discounting total patch changes 12 sec0.50.71.2-0.9-0.8-0.70.7-1.00.91.10.8-0.70.7-0.9
Delay discounting total patch changes 18 sec0.00.00.10.20.10.2-0.2-0.1-0.30.4-0.30.0-0.0-0.1
Delay discounting total patch changes 24 sec1.31.62.0-1.3-1.3-1.31.3-1.41.21.31.1-1.21.2-1.3
Delay discounting total patch changes 6 sec0.00.00.20.10.10.0-0.0-0.1-0.20.5-0.20.2-0.2-0.1
Delay discounting time to switch 0 sec0.20.20.30.30.50.5-0.50.6-0.5-0.5-0.50.5-0.50.4
Delay discounting water rate 0 sec0.10.10.2-0.2-0.3-0.20.2-0.20.20.30.3-0.40.4-0.3
Delay discounting water rate 12 sec2.13.15.0-2.0-1.8-1.81.8-1.31.81.32.2-1.71.7-1.6
Delay discounting water rate 18 sec0.50.71.3-0.9-0.9-1.01.0-0.21.00.41.2-0.70.7-0.7
Delay discounting water rate 24 sec2.12.84.6-1.8-1.6-1.51.5-1.61.51.72.2-1.71.7-1.7
Delay discounting water rate 6 sec1.52.23.1-1.7-1.6-1.51.5-1.21.41.21.8-1.51.5-1.5
Locomotor activity0.10.10.30.40.30.2-0.20.1-0.20.0-0.50.3-0.30.2
Locomotor testing distance0.81.32.01.41.11.1-1.11.0-1.1-0.9-1.41.1-1.11.0
Locomotor testing rearing0.81.21.51.21.21.2-1.20.8-1.2-0.7-1.21.1-1.11.0
Light reinforcement 14.48.19.12.82.92.9-2.92.5-3.0-2.5-2.83.0-3.02.8
Light reinforcement 23.14.14.82.12.02.0-2.02.1-1.9-1.9-2.22.0-2.02.1
Reaction time number correct0.50.71.30.90.80.7-0.71.0-0.8-1.1-0.50.8-0.80.9
Reaction time mean minus median0.10.10.20.30.40.4-0.40.1-0.4-0.1-0.50.5-0.50.2
Reaction time mean minus median AUC0.00.00.10.10.20.2-0.2-0.2-0.20.0-0.10.3-0.30.0
Reaction time num false alarms0.30.40.60.70.70.6-0.60.8-0.6-0.6-0.60.7-0.70.7
Reaction time num false alarms AUC0.60.91.31.00.90.9-0.91.1-0.9-0.9-0.91.0-1.01.0
Reaction time trials correct on left0.50.71.30.90.80.7-0.71.0-0.8-1.1-0.50.8-0.80.9
Reaction time trials on left0.50.81.40.90.80.8-0.81.0-0.8-1.2-0.50.8-0.81.0
Reaction time mean0.40.61.3-0.4-0.7-0.60.6-1.00.41.10.3-0.80.8-1.0
Reaction time mean AUC0.30.41.1-0.3-0.5-0.50.5-0.90.31.00.2-0.70.7-0.9
Median of all reaction times0.50.71.5-0.4-0.7-0.60.6-1.10.41.20.4-1.01.0-1.0
Reaction time omissions0.20.20.40.40.60.6-0.60.1-0.5-0.3-0.50.5-0.50.4
Reaction time false alarm rate0.10.10.20.30.30.3-0.30.4-0.3-0.1-0.50.3-0.30.3
Reaction time premature initiation rate0.20.20.3-0.5-0.5-0.50.5-0.50.50.40.4-0.50.5-0.4
Reaction time premature initiations0.00.00.10.0-0.0-0.00.00.10.1-0.30.10.0-0.00.1
Std. dev. reaction times0.10.20.4-0.3-0.3-0.30.3-0.60.30.60.2-0.30.3-0.5
Reaction time trials completed0.50.81.40.90.80.8-0.81.0-0.8-1.2-0.50.8-0.81.0
Reaction time trials AUC0.71.11.81.11.00.9-0.91.2-1.0-1.3-0.71.0-1.01.1
Social response proportion0.20.30.7-0.6-0.4-0.30.3-0.70.30.80.6-0.30.3-0.6
Social responses0.00.00.20.00.10.2-0.2-0.1-0.20.40.10.1-0.1-0.2
Social time0.40.61.3-0.8-0.6-0.50.5-0.80.61.20.9-0.60.6-0.9
Conditioned locomotion2.52.94.51.61.61.6-1.62.0-1.5-2.1-1.41.7-1.71.9
Cocaine response after cond. corrected2.52.83.51.91.71.7-1.71.5-1.9-1.5-1.81.6-1.61.6
Cocaine response after cond. not corrected3.53.94.22.02.02.0-2.01.9-2.0-2.0-1.92.0-2.02.0
Cocaine response before conditioning0.50.71.00.50.80.7-0.71.0-0.6-1.0-0.61.0-1.00.9
Saline control response1.01.31.81.31.21.2-1.20.9-1.2-0.8-1.41.1-1.11.0
Condit. Reinf. active minus inactive responses3.24.05.31.92.02.0-2.02.2-1.9-2.3-1.52.0-2.02.2
Condit. Reinf. active-inactive response ratio0.60.61.20.70.70.6-0.61.0-0.7-1.1-0.60.7-0.70.9
Condit. Reinf. active responses2.53.54.81.71.81.9-1.92.1-1.8-2.2-1.31.9-1.92.0
Condit. Reinf. inactive responses1.72.12.51.31.51.6-1.61.5-1.4-1.6-0.91.5-1.51.5
Condit. Reinf. lever presses1.42.03.11.31.41.3-1.31.7-1.3-1.7-0.91.4-1.41.6
Condit. Reinf. lever reinforcers received2.13.04.01.61.71.8-1.81.9-1.7-2.0-1.11.7-1.71.9
Pavlov. Cond. lever latency1.41.92.4-1.4-1.4-1.31.3-1.41.41.51.3-1.41.4-1.5
Pavlov. Cond. magazine entry latency0.10.20.20.40.40.4-0.40.5-0.4-0.4-0.30.4-0.40.4
Pavlov. Cond. change in total contacts0.40.51.00.80.60.6-0.61.0-0.6-1.0-0.50.7-0.70.8
Pavlov. Cond. index score0.60.71.20.80.80.8-0.81.0-0.8-1.1-0.70.8-0.81.0
Pavlov. Cond. latency score0.50.61.10.80.70.7-0.70.9-0.7-1.0-0.60.8-0.80.9
Pavlov. Cond. lever contacts0.60.81.40.90.90.8-0.81.0-0.9-1.2-0.80.9-0.91.0
Pavlov. Cond. magazine entry number0.00.10.2-0.2-0.2-0.20.2-0.50.10.30.3-0.20.2-0.2
Pavlov. Cond. intertrial magazine entries2.53.23.7-1.9-1.8-1.71.7-1.81.71.91.8-1.81.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.60.60.5-0.50.8-0.5-0.9-0.40.6-0.60.7
Pavlov. Cond. response bias1.31.82.51.21.31.2-1.21.5-1.3-1.6-1.21.4-1.41.4
Conditioned reinforcement - actives0.20.20.40.60.40.4-0.40.4-0.6-0.5-0.50.4-0.40.4
Conditioned reinforcement - inactives1.72.02.61.61.41.3-1.31.2-1.5-1.3-1.61.4-1.41.4
Conditioned locomotion0.10.10.1-0.1-0.4-0.30.3-0.30.10.30.2-0.30.3-0.4
Intermittent access intake day 1-15 change0.20.20.5-0.4-0.3-0.50.50.20.7-0.10.7-0.10.1-0.1
Intermittent access intake escalation0.40.40.9-0.7-0.6-0.80.8-0.10.90.20.9-0.30.3-0.4
Intermittent access intake escalation 21.11.01.7-1.1-1.1-1.21.2-0.71.30.71.3-0.80.8-0.9
Intermitt. access day 1 inactive lever presses0.00.00.10.2-0.1-0.20.2-0.3-0.00.2-0.30.0-0.0-0.1
Intermitt. access day 15 inactive lever presses4.24.65.62.32.12.1-2.12.1-2.0-1.9-2.42.2-2.22.1
Intermitt. access escalation Index0.40.41.4-0.5-0.4-0.40.4-1.00.31.20.3-0.50.5-0.7
Intermittent access day 1 total infusions5.05.67.42.62.42.5-2.51.8-2.7-2.0-2.62.3-2.32.2
Intermittent access day 15 total infusions1.41.51.91.41.21.2-1.21.2-1.2-1.2-1.31.3-1.31.3
Intermittent access terminal intake (last 3 days)1.41.52.11.41.21.3-1.31.1-1.3-1.1-1.41.1-1.11.2
Intermittent access total infusions1.71.92.41.61.31.5-1.51.2-1.5-1.3-1.51.3-1.31.3
Intermittent access day 1 locomotion2.82.93.51.71.71.8-1.81.3-1.9-1.4-1.71.8-1.81.6
Intermittent access day 15 total locomotion0.40.40.60.80.60.5-0.50.5-0.7-0.7-0.60.6-0.60.6
Intermittent access total locomotion0.20.30.50.70.40.5-0.50.2-0.7-0.3-0.60.5-0.50.4
Intermittent access standard deviation0.00.10.3-0.1-0.2-0.30.3-0.00.50.10.2-0.00.0-0.1
Cocaine induced anxiety0.00.10.10.20.30.2-0.20.1-0.3-0.1-0.40.2-0.20.2
Post-drug Anxiety0.60.61.1-0.7-0.8-0.60.6-0.90.50.90.4-1.01.0-0.9
Baseline Anxiety0.40.50.8-0.6-0.8-0.60.6-0.50.50.60.5-0.90.9-0.7
Lifetime Intake1.92.22.81.71.51.6-1.61.1-1.6-1.3-1.71.4-1.41.4
Incentive Sensitization - Responses0.10.10.2-0.2-0.3-0.30.3-0.30.2-0.10.4-0.50.5-0.3
Incentive Sensitization - Breakpoint0.20.20.4-0.3-0.5-0.50.5-0.40.40.10.5-0.60.6-0.5
Progressive ratio test 1 active lever presses0.40.40.60.80.60.7-0.70.4-0.7-0.5-0.80.5-0.50.6
Progressive ratio test 1 breakpoint0.30.30.60.80.50.6-0.60.4-0.7-0.5-0.80.4-0.40.5
Progressive ratio test 1 inactive lever presses1.01.11.71.21.11.0-1.00.7-1.2-0.7-1.31.1-1.11.0
Progressive ratio test 2 active lever presses0.00.00.10.2-0.2-0.10.1-0.2-0.2-0.2-0.1-0.30.3-0.1
Progressive ratio test 2 breakpoint0.00.00.10.3-0.1-0.00.0-0.1-0.2-0.3-0.2-0.20.2-0.0
Progressive ratio test 2 inactive lever presses0.60.71.11.10.80.8-0.80.6-1.0-0.8-1.00.7-0.70.8
Total sessions with >9 infusions0.70.71.00.90.90.9-0.90.4-0.8-0.5-0.91.0-1.00.8
Short access day 1 total inactive lever presses3.23.65.62.22.01.9-1.91.4-1.9-1.3-2.41.9-1.91.8
Short access day 10 total inactive lever presses0.30.30.70.60.50.4-0.40.6-0.5-0.5-0.50.8-0.80.6
Short access day 1 total infusions1.92.13.21.61.61.6-1.60.7-1.6-0.7-1.81.5-1.51.3
Short access day 10 total infusions3.23.64.42.11.92.0-2.01.5-2.1-1.8-2.11.7-1.71.9
Short access total infusions1.21.32.01.31.21.3-1.30.7-1.3-0.8-1.41.1-1.11.1
Short access day 1 locomotion4.44.65.42.22.22.2-2.22.0-2.1-1.9-2.32.2-2.22.1
Short access day 10 total locomotion1.11.21.51.21.11.1-1.10.9-1.2-0.8-1.21.2-1.21.0
Short access total locomotion0.40.40.50.70.60.7-0.70.2-0.7-0.2-0.70.6-0.60.5
Compulsive drug intake0.30.30.7-0.6-0.5-0.50.5-0.80.60.50.6-0.30.3-0.4
One hour access (0.3 mA shock)1.01.21.81.31.01.0-1.00.8-1.0-1.2-1.41.0-1.01.1
One hour access (shock baseline)1.31.52.21.51.21.2-1.21.2-1.3-1.2-1.51.0-1.01.2
Number of responses in last shaping day0.00.00.10.20.0-0.10.10.20.1-0.3-0.30.0-0.00.1
Context. condit. distance diff. score0.30.30.8-0.5-0.5-0.60.6-0.40.70.20.9-0.50.5-0.3
Locomotion velocity, session 10.00.10.1-0.1-0.2-0.20.2-0.20.30.30.1-0.20.2-0.3
Locomotion distance, session 12.22.83.41.71.71.6-1.61.6-1.5-1.6-1.81.8-1.81.7
Locomotion velocity, session 20.20.20.4-0.3-0.5-0.50.5-0.30.60.30.1-0.50.5-0.4
Locomotion distance, session 20.00.00.30.20.10.1-0.10.1-0.10.1-0.60.1-0.10.0
Locomotion velocity, session 30.30.40.70.60.60.6-0.60.4-0.7-0.8-0.80.3-0.30.6
Locomotion distance, session 31.11.21.91.21.11.0-1.01.1-1.2-0.9-1.41.1-1.11.0
Stereotopy head waving bouts, day 30.91.11.81.10.90.9-0.91.1-0.9-1.4-1.20.8-0.81.1
Stereotopy head waving duration, day 30.00.00.10.0-0.10.1-0.1-0.1-0.0-0.3-0.2-0.20.20.1
Locomotion velocity, session 70.50.60.90.80.70.7-0.70.9-0.8-0.8-1.00.6-0.60.8
Locomotion distance, session 70.10.10.2-0.2-0.3-0.40.4-0.10.30.10.1-0.50.5-0.2
Stereotopy head waving bouts, day 70.00.00.10.00.10.3-0.30.1-0.40.0-0.20.1-0.10.0
Stereotopy head waving duration, day 70.70.91.20.81.01.1-1.10.8-1.1-0.7-1.00.9-0.90.8
Locomotion velocity, session 80.00.00.10.2-0.00.0-0.0-0.30.00.0-0.3-0.10.1-0.1
Locomotion distance, session 80.10.10.50.30.30.1-0.10.7-0.1-0.5-0.20.4-0.40.4
Degree of sensitization distance1.61.62.0-1.3-1.3-1.21.2-1.11.31.01.4-1.41.4-1.2
Degree of sensitization stereotypy0.00.00.1-0.00.10.2-0.2-0.0-0.30.2-0.20.2-0.2-0.1
Condit. Reinf. active minus inactive responses0.30.30.8-0.3-0.6-0.40.4-0.40.60.60.2-0.90.9-0.6
Condit. Reinf. active-inactive response ratio0.20.20.5-0.3-0.5-0.40.4-0.40.50.60.1-0.70.7-0.5
Condit. Reinf. active responses0.50.61.31.00.70.8-0.80.9-0.6-0.8-1.10.4-0.40.7
Condit. Reinf. inactive responses1.61.92.21.51.41.3-1.31.4-1.2-1.5-1.41.3-1.31.5
Incentive salience index mean0.20.31.10.70.40.6-0.60.6-0.4-0.4-1.00.1-0.10.4
Condit. Reinf. lever presses1.41.93.51.41.31.5-1.51.4-1.3-1.1-1.91.2-1.21.2
Time in familiar zone, hab. session 10.60.61.0-0.7-0.7-0.70.7-0.90.81.00.6-0.70.7-0.8
Time in novel zone, hab. session 10.60.60.9-0.8-0.7-0.70.7-0.80.70.81.0-0.90.9-0.8
Total zone transitions, hab. session 10.10.10.20.30.40.4-0.40.4-0.3-0.4-0.50.4-0.40.4
Total locomotion distance, hab. session 10.00.10.20.00.20.1-0.10.2-0.1-0.4-0.30.3-0.30.2
Locomotion velocity, hab. session 10.81.11.70.91.00.9-0.91.2-1.0-1.3-1.01.1-1.11.1
Time in familiar zone, hab. session 20.00.00.10.10.10.0-0.00.1-0.00.2-0.20.1-0.1-0.0
Time in novel zone, hab. session 20.50.50.8-0.7-0.7-0.60.6-0.80.60.50.9-0.70.7-0.6
Total zone transitions, hab. session 20.20.20.40.30.40.3-0.30.6-0.2-0.5-0.60.6-0.60.4
Total locomotion distance, hab. session 20.10.20.50.30.30.3-0.30.6-0.3-0.7-0.30.5-0.50.5
Locomotion velocity, hab. session 20.40.50.90.50.70.6-0.60.9-0.6-0.9-0.60.8-0.80.8
Novel to familiar place preference ratio0.50.61.4-0.9-0.6-0.70.7-0.60.70.71.2-0.60.6-0.7
Novelty place preference1.01.02.0-1.2-0.9-1.01.0-0.81.01.01.4-0.90.9-1.0
Time in novel zone, NPP test1.31.42.3-1.3-1.1-1.11.1-1.01.11.21.5-1.11.1-1.1
Total zone transitions, NPP test1.52.23.01.41.41.4-1.41.6-1.2-1.4-1.71.6-1.61.5
Total locomotion distance, NPP test1.62.22.81.31.41.3-1.31.7-1.2-1.7-1.51.6-1.61.5
Locomotion velocity, NPP test3.24.55.41.92.12.0-2.02.3-1.9-2.3-2.22.2-2.22.2
Pavlov. Cond. lever latency1.72.23.7-1.7-1.3-1.41.4-1.71.31.41.9-1.31.3-1.4
Pavlov. Cond. magazine entry latency0.00.00.20.20.0-0.10.10.20.0-0.1-0.40.1-0.10.1
Pavlov. Cond. change in total contacts0.10.10.40.40.0-0.20.20.40.1-0.2-0.70.1-0.10.1
Pavlov. Cond. index score0.60.81.51.00.70.7-0.71.2-0.7-0.9-1.20.8-0.80.9
Pavlov. Cond. latency score0.50.71.41.00.70.6-0.61.1-0.7-0.9-1.20.7-0.70.8
Pavlov. Cond. lever contacts1.11.32.31.31.01.0-1.01.4-1.0-1.1-1.51.0-1.01.1
Pavlov. Cond. magazine entry number0.20.30.5-0.6-0.4-0.30.3-0.70.40.70.7-0.50.5-0.6
Pavlov. Cond. intertrial magazine entries1.72.02.51.51.41.6-1.61.3-1.6-1.3-1.31.3-1.31.4
Pavlov. Cond. lever-magazine prob. diff.1.51.93.01.51.21.2-1.21.7-1.2-1.4-1.71.3-1.31.4
Pavlov. Cond. response bias1.21.42.11.31.11.0-1.01.5-1.0-1.3-1.41.1-1.11.2
Bone: apparent density5.69.311.33.23.13.1-3.12.8-3.0-2.8-3.43.0-3.03.0
Bone surface2.13.75.22.01.81.8-1.81.9-1.7-1.9-2.31.9-1.91.9
Bone volume2.64.56.22.32.02.1-2.11.9-2.0-2.0-2.52.1-2.12.1
Bone: connectivity density5.58.711.23.12.92.9-2.92.8-2.9-2.7-3.32.9-2.92.9
Bone: cortical apparent density0.50.60.80.90.70.8-0.80.9-0.8-0.7-0.70.7-0.70.8
Bone: cortical area0.40.70.90.70.81.0-1.00.9-0.6-0.7-0.70.9-0.90.8
Bone: cortical porosity1.11.21.41.11.11.2-1.21.1-1.1-1.0-1.11.1-1.11.1
Bone: cortical porosity1.01.11.31.11.11.1-1.11.0-1.0-0.9-1.11.0-1.01.0
Bone: cortical thickness0.00.00.1-0.10.10.3-0.30.20.10.20.30.2-0.20.0
Bone: cortical thickness1.41.62.11.11.31.2-1.21.4-1.0-1.4-1.01.4-1.41.4
Bone: cortical tissue density0.30.40.60.80.60.7-0.70.8-0.7-0.6-0.50.5-0.50.7
Bone: elastic displacement0.91.01.30.81.01.0-1.01.0-0.8-0.9-0.91.1-1.11.1
Bone: elastic work1.21.52.01.01.21.2-1.21.3-1.0-1.1-1.41.3-1.31.3
Bone: endosteal estimation0.10.30.80.50.30.3-0.30.6-0.2-0.8-0.90.5-0.50.6
Bone: endosteal perimeter0.10.10.50.40.20.3-0.30.3-0.2-0.4-0.70.3-0.30.3
Bone: final force0.10.20.50.50.40.4-0.40.6-0.1-0.3-0.70.5-0.50.4
Bone: final moment0.10.20.40.40.40.4-0.40.6-0.0-0.3-0.60.5-0.50.4
Bone: marrow area0.20.40.90.60.40.4-0.40.6-0.2-0.9-1.00.6-0.60.7
Bone: maximum diameter1.01.92.21.41.31.5-1.51.4-1.2-1.3-1.51.3-1.31.3
Bone: maximum force0.00.00.10.10.10.2-0.20.30.10.0-0.20.2-0.20.1
Bone: maximum moment0.00.00.10.10.20.2-0.20.30.1-0.1-0.20.2-0.20.2
Bone: minimum diameter0.10.10.2-0.3-0.4-0.20.2-0.30.50.4-0.1-0.30.3-0.4
Bone: periosteal estimation0.40.91.40.90.80.9-0.91.0-0.6-1.0-1.21.0-1.01.0
Bone: periosteal perimeter0.20.30.40.40.40.7-0.70.6-0.4-0.5-0.60.5-0.50.5
Bone: post-yield work0.40.50.60.80.70.7-0.70.8-0.7-0.7-0.70.6-0.60.7
Bone: stiffness0.10.10.2-0.2-0.3-0.30.30.00.40.20.3-0.30.3-0.3
Bone: tissue strength0.30.30.6-0.5-0.5-0.40.4-0.70.30.80.5-0.60.6-0.6
Bone: trabecular number4.87.49.72.92.72.7-2.72.5-2.9-2.4-3.12.7-2.72.6
Bone: trabecular spacing1.82.42.8-1.6-1.5-1.41.4-1.51.61.71.4-1.51.5-1.7
Bone: trabecular thickness0.60.70.80.80.90.9-0.90.6-0.8-0.8-0.90.8-0.80.8
Bone: trabecular tissue density0.00.00.20.20.10.2-0.20.3-0.3-0.4-0.0-0.00.00.2
Breakpoint value in progressive ratio session0.70.81.21.00.91.0-1.00.7-1.0-0.7-1.10.8-0.80.9
Distance traveled before self-admin0.00.00.20.20.0-0.10.10.3-0.0-0.5-0.10.3-0.30.2
Distance traveled after self-admin0.20.20.6-0.2-0.4-0.30.3-0.70.20.50.5-0.50.5-0.6
Delta time in closed arm before/after self-admin0.10.10.1-0.3-0.3-0.40.4-0.10.30.20.1-0.20.2-0.2
Delta time in open arm before/after self-admin1.11.11.81.11.21.3-1.30.6-1.3-0.4-0.91.0-1.00.9
Diff in mean of infusions in LGA sessions0.20.30.60.60.60.7-0.70.1-0.8-0.2-0.50.1-0.10.4
Extinction: sum of active levers before priming1.01.01.11.01.01.0-1.01.1-1.0-0.9-0.91.0-1.01.0
Active lever presses in extinction session 60.00.00.10.10.00.0-0.0-0.30.10.1-0.1-0.00.0-0.0
Delta distance traveled before/after self-admin1.41.52.5-1.1-1.1-1.01.0-1.60.91.51.2-1.31.3-1.3
Delta ambulatory time before/after self-admin0.30.30.8-0.4-0.4-0.30.3-0.90.30.80.4-0.60.6-0.6
Time in closed arm before self-admin0.40.51.0-0.7-0.6-0.50.5-0.70.70.71.0-0.70.7-0.7
Time in closed arm after self-admin1.21.31.7-1.1-1.1-0.90.9-1.21.01.11.2-1.31.3-1.2
Time in open arm before self-admin0.10.10.30.20.1-0.00.00.4-0.1-0.6-0.50.3-0.30.3
Time in open arm after self-admin2.83.13.81.81.81.7-1.71.5-1.8-1.4-1.91.9-1.91.8
Sum of active levers in priming session hrs 5-61.21.11.51.11.11.1-1.11.1-1.0-1.0-1.21.0-1.01.1
Time to tail flick, vehicle, before self-admin1.61.62.0-1.3-1.3-1.11.1-1.01.21.31.4-1.41.4-1.3
Time to tail flick, vehicle, after self-admin3.13.33.7-1.7-1.8-1.81.8-1.71.91.91.6-1.91.9-1.9
Time to tail flick, test, before self-admin0.60.60.80.80.90.8-0.80.7-0.7-0.7-0.80.8-0.80.8
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.4-0.30.3-0.10.40.00.3-0.40.4-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.2-0.3-0.60.6-0.20.60.10.0-0.20.2-0.2
Delta time to tail flick, test, before/after SA0.20.20.60.30.20.2-0.20.7-0.3-0.8-0.30.3-0.30.5
Ambulatory time before self-admin0.20.20.60.50.30.3-0.30.6-0.4-0.8-0.30.5-0.50.5
Ambulatory time after self-admin0.10.10.3-0.1-0.3-0.20.2-0.60.10.50.4-0.40.4-0.4
Total heroin consumption2.42.93.21.81.81.7-1.71.7-1.6-1.6-1.71.7-1.71.8
Area under the delay curve1.41.51.81.41.11.2-1.21.1-1.2-1.2-1.31.3-1.31.2
Delay disc. indifference point, 0s delay0.40.40.9-0.7-0.6-0.50.5-0.60.60.51.0-0.60.6-0.6
Delay disc. indifference point, 16s delay1.71.72.11.41.31.3-1.31.0-1.4-1.2-1.51.3-1.31.3
Delay disc. indifference point, 2s delay0.00.00.0-0.0-0.0-0.00.0-0.10.00.10.0-0.10.1-0.1
Delay disc. indifference point, 24s delay5.35.15.92.42.22.0-2.02.4-2.2-2.4-2.42.3-2.32.3
Delay disc. indifference point, 4s delay0.20.20.40.50.40.4-0.40.3-0.6-0.4-0.60.5-0.50.4
Delay disc. indifference point, 8s delay1.41.41.91.31.11.1-1.11.0-1.1-1.1-1.41.3-1.31.1
Delay discount exponential model param2.22.32.8-1.7-1.4-1.41.4-1.41.51.51.7-1.61.6-1.4
Delay discount hyperbolic model param1.92.02.4-1.5-1.3-1.31.3-1.31.41.41.5-1.51.5-1.4
Fecal boli incidents, locomotor time 10.60.70.90.90.81.0-1.00.8-0.8-0.9-0.90.6-0.60.8
Change in fecal boli incidents, locomotor task4.24.04.4-2.0-1.9-2.02.0-2.11.92.12.1-2.02.0-2.0
Time >=10cm from walls, locomotor time 10.10.10.20.30.20.1-0.10.4-0.0-0.30.30.1-0.10.3
Bouts of movement, locomotor time 14.14.65.82.02.02.0-2.02.3-2.0-2.4-2.22.1-2.12.2
Total resting periods, locomotor time 13.94.45.72.02.02.0-2.02.3-1.9-2.4-2.12.1-2.12.2
Rest time, locomotor task time 10.00.00.10.1-0.00.0-0.00.30.0-0.2-0.3-0.20.20.1
Distance moved, locomotor task time 10.60.61.3-0.8-0.7-0.70.7-1.10.71.10.8-0.60.6-0.9
Vertical activity count, locomotor time 10.40.40.8-0.7-0.6-0.70.7-0.70.80.50.9-0.40.4-0.6
Time >=10cm from walls, locomotor time 20.00.00.20.1-0.1-0.20.20.00.2-0.00.4-0.00.00.0
Bouts of movement, locomotor time 20.20.20.4-0.4-0.5-0.60.6-0.00.6-0.00.4-0.40.4-0.2
Total resting periods, locomotor time 20.10.10.1-0.2-0.3-0.30.30.20.4-0.20.2-0.30.3-0.0
Rest time, locomotor task time 21.61.92.51.51.31.5-1.51.6-1.6-1.5-1.40.9-0.91.4
Distance moved, locomotor task time 20.91.01.7-1.1-0.9-0.90.9-1.31.01.31.1-0.70.7-1.1
Vertical activity count, locomotor time 21.41.52.5-1.3-1.2-1.41.4-1.11.61.01.4-0.90.9-1.1
Weight adjusted by age0.10.20.3-0.3-0.4-0.50.5-0.30.30.50.4-0.30.3-0.4
Seeking ratio, delayed vs. immediate footshock0.30.40.7-0.6-0.5-0.60.6-0.80.60.80.6-0.40.4-0.6
Locomotion in novel chamber1.31.61.8-1.4-1.2-1.11.1-1.31.31.31.3-1.31.3-1.2
Locomotion in novel chamber post-restriction1.61.92.2-1.3-1.4-1.41.4-1.51.31.41.2-1.41.4-1.5
Progressive ratio0.70.81.0-0.9-0.9-0.80.8-0.91.00.91.0-0.80.8-0.9
Food seeking constrained by brief footshock2.53.03.51.91.71.6-1.61.8-1.8-1.7-1.81.7-1.71.8
Seeking ratio, punishment vs. effort1.72.12.41.51.41.3-1.31.6-1.5-1.5-1.51.4-1.41.5
Run reversals in cocaine runway, females0.00.00.1-0.1-0.1-0.10.10.20.0-0.30.3-0.10.10.0
Run reversals in cocaine runway, males0.60.61.00.70.80.7-0.71.0-0.5-0.7-0.70.9-0.90.8
Latency to leave start box in cocaine runway0.40.40.80.70.70.7-0.70.5-0.9-0.5-0.70.7-0.70.6
Latency to leave start box in cocaine runway, F0.60.61.00.90.80.8-0.80.7-0.9-0.5-1.00.8-0.80.7
Latency to leave start box in cocaine runway, M0.10.00.20.10.20.1-0.10.2-0.4-0.40.00.2-0.20.2
Cd content in liver0.10.10.10.30.30.3-0.30.2-0.2-0.2-0.40.3-0.30.2
Co content in liver7.68.99.92.93.13.0-3.02.8-2.7-2.8-3.13.1-3.13.0
Cu content in liver0.30.41.50.90.50.5-0.50.4-0.4-0.3-1.20.4-0.40.4
Fe content in liver0.10.10.20.1-0.3-0.30.3-0.20.40.3-0.1-0.30.3-0.3
K content in liver0.40.41.0-0.6-0.8-0.80.8-0.51.00.30.4-0.70.7-0.6
Mg content in liver0.30.30.7-0.3-0.7-0.70.7-0.50.90.4-0.1-0.60.6-0.6
Mn content in liver0.20.20.50.30.50.4-0.40.7-0.2-0.7-0.30.5-0.50.6
Na content in liver0.20.20.90.40.20.2-0.20.5-0.1-0.5-0.90.3-0.30.4
Rb content in liver0.00.00.10.0-0.2-0.20.2-0.20.10.0-0.2-0.10.1-0.1
Se content in liver0.50.60.8-0.6-0.7-0.80.8-0.90.90.90.6-0.80.8-0.8
Sr content in liver0.20.20.3-0.5-0.4-0.50.5-0.20.40.10.3-0.40.4-0.3
Zn content in liver0.20.31.2-0.2-0.3-0.30.3-0.90.31.1-0.1-0.30.3-0.7