Hub : Genes

AABR07044362.1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000026051 0.1 0.07 1.5e-07 0.02 0.04 0.05 0.04 3.9e-03 8.1e-06 3.6e-06 2.6e-05
2 Adipose intron excision ratio chr20:2624215:2624418 0.34 0.15 0.0e+00 0.06 0.08 0.1 0.1 3.0e-07 8.0e-09 8.7e-11 3.8e-11
3 Adipose intron excision ratio chr20:2633040:2633243 0.34 0.15 0.0e+00 0.06 0.08 0.1 0.1 3.0e-07 8.0e-09 8.7e-11 3.9e-11
4 Adipose intron excision ratio chr20:2670814:2671007 0.16 0.09 7.2e-11 0.08 0.06 0.07 0.08 5.3e-09 4.6e-07 1.3e-08 1.5e-09
5 BLA gene expression ENSRNOG00000026051 0.76 0.08 0.0e+00 0.54 0.58 0.59 0.59 1.6e-33 1.0e-37 3.6e-38 2.1e-38
6 Brain gene expression ENSRNOG00000026051 0.45 0.04 0.0e+00 0.65 0.63 0.65 0.65 1.2e-78 5.4e-75 2.1e-78 3.0e-78
7 IL gene expression ENSRNOG00000026051 0.72 0.12 5.6e-17 0.43 0.41 0.44 0.46 1.1e-11 4.8e-11 9.0e-12 1.2e-12
8 LHb gene expression ENSRNOG00000026051 0.59 0.18 5.8e-12 0.37 0.36 0.42 0.42 1.3e-09 1.4e-09 3.1e-11 5.4e-11
9 NAcc gene expression ENSRNOG00000026051 0.67 0.12 0.0e+00 0.53 0.16 0.55 0.01 2.3e-46 4.3e-12 6.0e-48 3.6e-02
10 OFC gene expression ENSRNOG00000026051 0.79 0.12 0.0e+00 0.47 0.42 0.41 0.44 1.0e-12 4.9e-11 8.3e-11 8.9e-12
11 PL gene expression ENSRNOG00000026051 0.85 0.04 0.0e+00 0.65 0.07 0.69 -0 9.6e-64 9.2e-06 8.7e-72 5.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.54.87.52.2-0.4-0.50.6-2.7-2.6-2.7-2.6-2.7-2.5-2.6
BMI without tail3.16.49.41.6-1.4-1.51.6-3.1-2.9-2.9-2.9-3.0-2.9-3.1
Body weight5.924.834.02.5-3.5-3.63.8-5.7-5.8-5.4-5.6-5.8-5.8-5.8
Epididymis fat weight4.410.430.65.54.64.5-4.1-2.2-1.4-2.6-2.1-1.8-1.4-1.4
Glucose2.84.312.5-3.5-3.1-3.13.01.10.71.41.10.70.60.6
Heart weight0.10.10.3-0.0-0.4-0.40.4-0.3-0.5-0.4-0.4-0.5-0.2-0.5
Left kidney weight3.49.814.21.9-1.8-1.92.0-3.7-3.8-3.5-3.6-3.8-3.6-3.7
Right kidney weight3.39.312.61.0-2.6-2.72.8-3.3-3.6-3.1-3.2-3.5-3.4-3.5
Tail length5.616.825.2-0.5-5.0-5.05.0-3.8-4.1-3.5-3.7-4.1-4.2-4.3
Length with tail4.817.621.10.3-4.5-4.54.6-4.2-4.5-3.9-4.2-4.5-4.6-4.5
Length without tail3.27.09.60.8-2.4-2.42.6-2.9-3.1-2.7-2.8-2.9-3.0-2.9
Liver weight, left1.01.74.3-0.8-2.0-2.02.1-0.7-1.0-0.5-0.8-0.9-1.0-0.9
Liver weight, right4.57.514.6-0.9-3.8-3.83.8-2.2-2.5-1.9-2.1-2.4-2.6-2.6
Parametrial fat weight1.83.55.51.7-0.4-0.50.6-2.3-2.2-2.2-2.3-2.3-2.2-2.2
Retroperitoneal fat weight0.31.11.81.0-0.2-0.30.4-1.3-1.2-1.2-1.3-1.4-1.2-1.2
Intraocular pressure0.91.21.7-0.70.70.7-0.91.31.21.21.31.31.31.2
Extensor digitorum longus weight0.20.72.0-0.9-1.4-1.41.4-0.2-0.3-0.1-0.2-0.3-0.4-0.4
Soleus weight1.85.115.7-2.6-4.0-3.93.8-0.5-0.9-0.2-0.5-0.8-0.9-0.9
Tibialis anterior weight0.20.82.41.31.51.5-1.5-0.20.1-0.3-0.2-0.10.00.0
Tibia length3.08.413.6-0.4-3.7-3.73.7-2.6-3.0-2.3-2.5-2.8-2.9-2.9
Number of licking bursts0.40.51.7-1.3-0.9-0.90.80.60.40.70.50.60.40.4
Food consumed during 24 hour testing period1.11.42.9-0.4-1.6-1.61.7-0.9-1.1-0.7-0.8-1.0-1.1-1.1
Times rat made contact with spout1.92.24.40.72.12.1-2.11.11.41.01.01.21.31.4
Mean time between licks in bursts1.52.15.9-2.4-2.4-2.42.30.40.00.70.50.3-0.00.0
Mean num. licks in bursts0.91.13.31.51.81.8-1.70.00.3-0.20.0-0.00.30.3
Std. dev. time between licks in bursts1.61.95.6-2.1-2.4-2.42.30.0-0.30.30.1-0.1-0.4-0.3
Water consumed over 24 hours0.10.10.2-0.4-0.5-0.40.40.0-0.10.1-0.0-0.0-0.0-0.0
Indifference point 0 sec0.71.13.71.91.51.5-1.3-0.8-0.4-0.8-0.8-0.5-0.5-0.5
Indifference point AUC2.22.53.80.9-1.0-1.01.0-1.8-1.9-1.8-1.8-1.7-1.9-1.9
Indifference point function ln k0.40.61.3-1.1-0.5-0.40.30.90.60.90.90.70.80.7
Indifference point function log k0.40.61.3-1.1-0.5-0.40.30.90.60.90.90.70.80.7
Delay discounting total patch changes 0 sec1.01.64.92.21.71.6-1.5-1.0-0.6-1.1-1.0-0.7-0.6-0.7
Delay discounting total patch changes 12 sec1.11.54.52.11.41.3-1.2-1.1-0.8-1.2-1.1-0.7-0.8-0.9
Delay discounting total patch changes 18 sec1.62.16.02.32.52.4-2.3-0.40.0-0.6-0.40.0-0.1-0.1
Delay discounting total patch changes 24 sec2.32.98.51.92.92.9-2.70.61.10.30.30.80.71.0
Delay discounting total patch changes 6 sec1.32.06.22.52.12.0-1.9-1.0-0.5-1.1-0.9-0.6-0.7-0.7
Delay discounting time to switch 0 sec0.71.02.60.81.61.6-1.50.50.80.50.50.70.70.8
Delay discounting water rate 0 sec0.40.61.10.7-0.1-0.10.1-0.9-0.9-1.0-0.8-0.9-0.7-1.0
Delay discounting water rate 12 sec0.30.41.30.51.01.0-1.10.20.40.00.30.30.30.2
Delay discounting water rate 18 sec0.20.30.40.1-0.5-0.50.5-0.6-0.5-0.6-0.6-0.6-0.6-0.7
Delay discounting water rate 24 sec1.42.03.21.2-0.4-0.40.5-1.7-1.8-1.8-1.5-1.6-1.5-1.8
Delay discounting water rate 6 sec0.20.20.80.60.80.8-0.9-0.10.1-0.3-0.1-0.1-0.0-0.1
Locomotor activity2.43.89.7-1.3-3.1-3.13.1-1.1-1.4-0.8-1.1-1.4-1.4-1.4
Locomotor testing distance0.40.61.8-0.7-1.3-1.31.3-0.3-0.4-0.2-0.4-0.6-0.4-0.4
Locomotor testing rearing0.91.33.2-0.7-1.8-1.81.8-0.7-1.0-0.5-0.8-0.9-0.9-0.8
Light reinforcement 10.20.40.90.90.90.9-0.9-0.4-0.2-0.5-0.3-0.4-0.2-0.3
Light reinforcement 20.70.91.1-0.1-1.0-1.01.0-1.0-1.1-0.9-0.9-1.0-1.0-1.0
Reaction time number correct0.60.82.31.51.51.5-1.5-0.3-0.1-0.4-0.2-0.00.0-0.2
Reaction time mean minus median2.63.49.9-2.8-3.2-3.13.10.40.10.70.30.1-0.10.0
Reaction time mean minus median AUC1.82.25.9-2.4-2.4-2.42.30.60.30.80.60.40.20.3
Reaction time num false alarms0.40.50.80.0-0.7-0.70.7-0.7-0.8-0.7-0.7-0.9-0.6-0.9
Reaction time num false alarms AUC0.60.81.30.2-0.9-0.90.8-1.0-1.1-0.9-0.9-1.1-0.9-1.1
Reaction time trials correct on left0.60.82.31.51.51.5-1.5-0.3-0.1-0.4-0.2-0.00.0-0.2
Reaction time trials on left0.50.72.11.41.41.4-1.4-0.4-0.2-0.5-0.2-0.10.0-0.2
Reaction time mean2.12.88.1-2.9-2.6-2.62.50.90.51.00.80.50.50.5
Reaction time mean AUC2.22.98.2-2.9-2.6-2.62.50.90.51.00.80.50.50.5
Median of all reaction times1.31.75.2-2.3-1.9-1.91.80.80.50.90.80.50.60.5
Reaction time omissions1.52.05.6-2.4-2.3-2.22.20.60.30.70.60.40.30.2
Reaction time false alarm rate0.71.12.6-0.7-1.6-1.61.6-0.6-0.8-0.5-0.6-0.9-0.7-0.8
Reaction time premature initiation rate1.21.52.41.1-0.2-0.30.4-1.5-1.4-1.5-1.5-1.5-1.5-1.4
Reaction time premature initiations1.52.13.82.00.50.5-0.3-1.7-1.6-1.8-1.7-1.6-1.6-1.6
Std. dev. reaction times2.73.710.8-2.8-3.3-3.33.20.4-0.00.60.2-0.1-0.1-0.1
Reaction time trials completed0.50.72.11.41.41.4-1.4-0.4-0.2-0.5-0.2-0.10.0-0.2
Reaction time trials AUC0.50.82.11.41.41.4-1.4-0.3-0.1-0.4-0.1-0.00.1-0.2
Social response proportion0.30.30.8-0.5-0.9-0.90.9-0.2-0.3-0.1-0.2-0.2-0.3-0.3
Social responses0.10.20.40.2-0.4-0.40.4-0.5-0.5-0.5-0.4-0.4-0.4-0.6
Social time1.72.26.8-2.1-2.6-2.62.5-0.0-0.30.2-0.1-0.2-0.4-0.2
Conditioned locomotion0.70.91.20.0-1.0-1.01.1-0.9-1.0-0.8-0.9-1.0-1.0-1.0
Cocaine response after cond. corrected0.40.50.8-0.20.60.6-0.60.80.80.70.70.90.80.8
Cocaine response after cond. not corrected0.30.41.0-0.5-1.0-1.01.0-0.3-0.4-0.2-0.3-0.3-0.4-0.5
Cocaine response before conditioning5.06.17.60.1-2.6-2.72.7-2.5-2.7-2.3-2.4-2.6-2.7-2.8
Saline control response1.11.53.31.80.90.9-0.8-1.4-1.1-1.4-1.3-1.2-1.2-1.1
Condit. Reinf. active minus inactive responses1.21.52.20.4-1.0-1.01.0-1.4-1.5-1.3-1.3-1.3-1.4-1.5
Condit. Reinf. active-inactive response ratio2.82.93.90.3-1.6-1.61.7-1.8-2.0-1.7-1.7-1.8-1.9-2.0
Condit. Reinf. active responses0.00.00.0-0.2-0.2-0.20.10.0-0.00.0-0.00.10.0-0.0
Condit. Reinf. inactive responses1.51.82.6-0.70.90.9-1.01.51.61.51.51.61.61.6
Condit. Reinf. lever presses0.40.50.9-0.60.40.4-0.50.80.80.70.80.90.80.8
Condit. Reinf. lever reinforcers received0.00.10.2-0.4-0.2-0.20.20.20.10.20.20.30.20.1
Pavlov. Cond. lever latency0.30.30.50.2-0.5-0.50.6-0.6-0.6-0.5-0.6-0.7-0.7-0.6
Pavlov. Cond. magazine entry latency0.60.70.9-0.1-0.9-0.90.9-0.9-0.9-0.8-0.8-0.8-0.9-0.9
Pavlov. Cond. change in total contacts0.10.20.40.60.30.3-0.3-0.5-0.4-0.6-0.6-0.3-0.4-0.5
Pavlov. Cond. index score0.00.00.0-0.1-0.1-0.10.0-0.1-0.1-0.1-0.10.0-0.0-0.1
Pavlov. Cond. latency score0.00.00.10.1-0.0-0.00.0-0.3-0.3-0.3-0.3-0.2-0.2-0.3
Pavlov. Cond. lever contacts0.30.41.00.41.01.0-1.00.30.40.20.30.50.50.4
Pavlov. Cond. magazine entry number0.30.30.5-0.30.30.3-0.40.70.70.70.70.60.60.7
Pavlov. Cond. intertrial magazine entries1.31.73.8-2.0-1.0-0.90.81.51.21.51.51.31.21.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.1-0.1-0.10.0-0.1-0.1-0.1-0.10.0-0.0-0.1
Pavlov. Cond. response bias0.10.10.2-0.10.40.4-0.40.30.30.20.20.40.30.3
Conditioned reinforcement - actives0.30.30.50.6-0.1-0.10.2-0.7-0.6-0.6-0.7-0.4-0.7-0.6
Conditioned reinforcement - inactives1.01.12.41.60.40.3-0.2-1.4-1.1-1.2-1.3-0.8-1.1-1.1
Conditioned locomotion0.00.00.1-0.1-0.4-0.40.4-0.2-0.1-0.0-0.0-0.1-0.3-0.0
Intermittent access intake day 1-15 change0.60.61.00.6-0.3-0.30.4-1.0-1.0-1.0-0.8-0.8-1.0-1.0
Intermittent access intake escalation0.50.50.9-0.3-1.0-1.00.9-0.6-0.7-0.5-0.4-0.5-0.6-0.7
Intermittent access intake escalation 21.51.54.6-1.7-2.1-2.12.00.0-0.20.10.1-0.0-0.2-0.3
Intermitt. access day 1 inactive lever presses0.40.41.2-0.6-1.1-1.11.0-0.3-0.5-0.3-0.3-0.3-0.4-0.5
Intermitt. access day 15 inactive lever presses2.12.33.71.2-0.5-0.60.7-1.8-1.8-1.9-1.8-1.6-1.8-1.9
Intermitt. access escalation Index3.02.73.9-1.10.80.8-0.82.01.92.01.82.01.92.0
Intermittent access day 1 total infusions0.60.71.00.10.80.9-0.80.80.90.80.71.00.80.9
Intermittent access day 15 total infusions0.10.10.20.20.40.4-0.40.20.30.20.20.30.20.3
Intermittent access terminal intake (last 3 days)0.10.10.20.50.30.2-0.2-0.3-0.1-0.3-0.3-0.1-0.3-0.2
Intermittent access total infusions0.10.10.20.40.50.5-0.40.10.20.10.10.20.10.2
Intermittent access day 1 locomotion0.20.30.4-0.6-0.4-0.40.40.50.60.60.30.50.40.6
Intermittent access day 15 total locomotion1.21.32.3-0.3-1.5-1.51.5-1.0-1.1-0.8-0.9-1.0-1.2-1.0
Intermittent access total locomotion0.70.81.7-0.3-1.3-1.31.3-0.7-0.7-0.6-0.7-0.7-0.8-0.7
Intermittent access standard deviation2.12.33.61.70.0-0.00.0-1.9-1.7-1.9-1.7-1.7-1.7-1.8
Cocaine induced anxiety2.22.55.2-2.3-0.8-0.80.61.81.71.91.81.61.71.7
Post-drug Anxiety0.90.92.1-1.5-0.6-0.60.41.11.01.11.11.01.00.9
Baseline Anxiety0.40.41.11.01.01.0-1.0-0.3-0.1-0.3-0.2-0.0-0.1-0.1
Lifetime Intake0.00.10.10.30.40.4-0.30.10.10.10.00.20.00.2
Incentive Sensitization - Responses0.60.60.8-0.40.70.7-0.70.90.90.80.80.90.90.9
Incentive Sensitization - Breakpoint0.70.71.0-0.50.60.6-0.71.00.90.91.01.01.01.0
Progressive ratio test 1 active lever presses0.20.20.40.10.40.5-0.30.50.50.50.30.60.50.6
Progressive ratio test 1 breakpoint0.20.20.40.20.60.6-0.50.50.50.50.20.60.40.6
Progressive ratio test 1 inactive lever presses0.40.51.31.01.11.1-1.10.00.2-0.00.00.40.20.1
Progressive ratio test 2 active lever presses0.70.81.1-0.10.90.9-0.90.90.90.90.81.00.91.0
Progressive ratio test 2 breakpoint1.21.31.8-0.11.21.2-1.21.21.21.11.11.41.21.3
Progressive ratio test 2 inactive lever presses0.30.30.40.3-0.5-0.50.6-0.6-0.6-0.5-0.7-0.4-0.6-0.6
Total sessions with >9 infusions0.00.00.10.30.00.00.1-0.2-0.2-0.1-0.3-0.2-0.3-0.0
Short access day 1 total inactive lever presses0.91.13.3-1.2-1.8-1.81.7-0.2-0.3-0.0-0.2-0.3-0.3-0.3
Short access day 10 total inactive lever presses0.20.20.7-0.7-0.9-0.90.8-0.0-0.10.00.10.1-0.0-0.2
Short access day 1 total infusions0.30.30.6-0.40.20.2-0.20.60.70.70.60.50.60.8
Short access day 10 total infusions0.10.10.30.50.10.1-0.0-0.3-0.3-0.3-0.3-0.3-0.4-0.2
Short access total infusions0.00.00.10.40.10.1-0.0-0.2-0.2-0.2-0.3-0.2-0.3-0.1
Short access day 1 locomotion2.83.04.6-1.40.60.7-0.82.12.12.12.02.01.92.1
Short access day 10 total locomotion0.70.82.5-1.1-1.6-1.61.5-0.0-0.30.00.0-0.2-0.2-0.2
Short access total locomotion0.20.20.3-0.6-0.4-0.40.40.50.40.50.40.40.20.5
Compulsive drug intake2.82.84.2-1.50.40.4-0.62.02.02.01.91.92.02.0
One hour access (0.3 mA shock)0.60.61.2-0.40.30.3-0.31.01.01.00.81.10.91.0
One hour access (shock baseline)0.50.60.80.2-0.7-0.70.9-0.8-0.8-0.7-0.8-0.7-0.9-0.8
Number of responses in last shaping day0.20.20.40.1-0.5-0.50.6-0.4-0.4-0.3-0.5-0.6-0.5-0.4
Context. condit. distance diff. score5.06.112.3-3.5-0.9-0.80.62.92.53.02.92.82.42.5
Locomotion velocity, session 10.20.20.6-0.8-0.4-0.40.40.50.30.50.40.40.30.3
Locomotion distance, session 10.60.81.80.51.41.4-1.30.60.70.50.50.60.70.8
Locomotion velocity, session 20.10.10.2-0.4-0.5-0.50.50.1-0.10.10.0-0.0-0.0-0.0
Locomotion distance, session 20.30.40.5-0.20.60.6-0.60.70.60.60.60.60.70.7
Locomotion velocity, session 30.20.30.80.90.80.8-0.7-0.2-0.2-0.3-0.2-0.1-0.1-0.1
Locomotion distance, session 31.51.62.4-0.60.90.9-1.01.41.41.41.41.51.51.5
Stereotopy head waving bouts, day 31.92.33.4-0.1-1.7-1.81.8-1.4-1.6-1.3-1.3-1.5-1.6-1.6
Stereotopy head waving duration, day 31.31.62.10.0-1.3-1.31.4-1.3-1.4-1.2-1.2-1.3-1.4-1.4
Locomotion velocity, session 73.74.15.9-1.60.90.9-1.02.42.32.42.42.42.42.4
Locomotion distance, session 73.74.76.4-1.01.61.7-1.72.52.52.42.42.52.52.5
Stereotopy head waving bouts, day 71.72.02.80.9-0.8-0.80.9-1.7-1.6-1.6-1.6-1.6-1.6-1.7
Stereotopy head waving duration, day 72.43.04.10.8-1.2-1.31.3-2.0-2.0-1.9-1.9-2.0-2.0-2.0
Locomotion velocity, session 82.02.46.8-2.4-2.6-2.62.50.3-0.30.50.40.1-0.3-0.2
Locomotion distance, session 82.63.97.5-2.7-0.5-0.50.32.42.02.42.32.32.02.1
Degree of sensitization distance0.40.41.1-1.1-0.6-0.60.50.60.60.70.70.50.40.5
Degree of sensitization stereotypy1.11.21.70.8-0.5-0.60.6-1.3-1.2-1.3-1.3-1.3-1.2-1.3
Condit. Reinf. active minus inactive responses0.70.71.2-0.80.30.3-0.31.11.11.01.01.01.01.0
Condit. Reinf. active-inactive response ratio0.10.10.30.50.50.5-0.5-0.10.1-0.1-0.1-0.1-0.00.0
Condit. Reinf. active responses1.11.31.9-0.70.60.7-0.71.41.31.31.31.31.31.4
Condit. Reinf. inactive responses2.02.43.1-0.31.51.5-1.61.71.61.51.61.71.71.7
Incentive salience index mean1.31.63.6-1.9-0.6-0.60.51.51.31.51.41.31.31.3
Condit. Reinf. lever presses2.33.17.4-2.7-0.9-0.90.72.01.72.12.01.81.71.7
Time in familiar zone, hab. session 14.03.76.10.52.42.4-2.51.71.91.51.61.92.02.0
Time in novel zone, hab. session 12.22.24.3-0.7-2.0-2.02.1-1.2-1.3-1.0-1.1-1.3-1.4-1.4
Total zone transitions, hab. session 10.60.81.2-0.50.60.7-0.71.01.10.90.91.01.01.0
Total locomotion distance, hab. session 10.50.81.1-0.20.80.8-0.90.91.10.80.90.91.01.0
Locomotion velocity, hab. session 10.30.40.80.20.90.9-0.90.60.70.50.50.50.70.6
Time in familiar zone, hab. session 20.40.40.80.20.80.8-0.90.50.50.40.50.50.70.6
Time in novel zone, hab. session 20.30.30.50.2-0.4-0.40.5-0.6-0.5-0.6-0.6-0.6-0.7-0.6
Total zone transitions, hab. session 20.10.10.40.50.60.6-0.60.00.1-0.0-0.10.00.10.1
Total locomotion distance, hab. session 21.11.42.0-0.21.11.1-1.21.31.41.21.21.21.41.4
Locomotion velocity, hab. session 21.11.52.2-0.31.11.1-1.11.41.41.21.31.31.51.4
Novel to familiar place preference ratio0.10.10.30.50.60.6-0.5-0.10.0-0.1-0.1-0.1-0.1-0.0
Novelty place preference0.10.10.30.50.30.3-0.2-0.3-0.2-0.4-0.3-0.3-0.3-0.3
Time in novel zone, NPP test0.10.20.20.50.10.1-0.0-0.5-0.4-0.5-0.5-0.5-0.5-0.4
Total zone transitions, NPP test1.01.42.0-0.70.70.7-0.81.41.41.31.31.41.41.4
Total locomotion distance, NPP test1.21.72.2-0.11.31.3-1.41.31.51.21.31.31.51.4
Locomotion velocity, NPP test2.02.83.7-0.21.61.7-1.71.81.91.61.71.81.91.9
Pavlov. Cond. lever latency1.62.06.22.51.81.8-1.7-1.1-0.7-1.2-1.0-0.9-0.7-0.7
Pavlov. Cond. magazine entry latency1.62.16.4-2.5-1.8-1.71.61.20.91.41.31.10.80.9
Pavlov. Cond. change in total contacts1.31.43.8-1.0-2.0-2.01.9-0.6-0.8-0.4-0.5-0.7-0.9-0.8
Pavlov. Cond. index score2.12.68.1-2.8-2.1-2.11.91.30.91.51.31.10.80.9
Pavlov. Cond. latency score1.82.37.0-2.6-2.2-2.12.00.90.61.11.00.80.50.6
Pavlov. Cond. lever contacts1.41.74.8-2.2-2.1-2.01.90.60.20.70.60.40.20.2
Pavlov. Cond. magazine entry number1.72.25.52.31.11.1-0.9-1.6-1.3-1.7-1.6-1.5-1.2-1.3
Pavlov. Cond. intertrial magazine entries1.21.43.61.21.91.9-1.90.60.80.40.50.60.80.8
Pavlov. Cond. lever-magazine prob. diff.2.12.78.0-2.8-2.0-1.91.71.41.01.61.41.20.91.0
Pavlov. Cond. response bias2.12.67.6-2.7-1.8-1.71.61.51.11.61.51.31.11.1
Bone: apparent density1.62.63.80.11.81.8-2.01.61.71.41.51.71.71.7
Bone surface0.20.30.6-0.2-0.8-0.80.7-0.4-0.5-0.4-0.5-0.4-0.5-0.5
Bone volume0.10.10.30.50.20.2-0.3-0.3-0.3-0.4-0.4-0.2-0.3-0.3
Bone: connectivity density2.33.75.1-1.01.21.2-1.42.32.32.22.12.22.22.3
Bone: cortical apparent density0.91.13.71.91.31.3-1.2-0.8-0.5-0.9-0.9-0.7-0.6-0.5
Bone: cortical area2.13.14.31.3-1.0-1.01.2-2.1-2.0-2.0-2.0-2.1-2.0-2.0
Bone: cortical porosity0.50.51.01.00.40.3-0.3-0.9-0.7-0.9-0.8-0.7-0.7-0.7
Bone: cortical porosity0.60.60.90.2-0.7-0.70.7-0.9-0.9-0.8-0.8-0.9-0.9-1.0
Bone: cortical thickness3.15.112.83.61.21.2-0.9-2.5-2.1-2.7-2.6-2.4-2.2-2.1
Bone: cortical thickness1.31.65.12.31.71.6-1.5-0.9-0.6-1.0-1.0-0.7-0.7-0.6
Bone: cortical tissue density0.70.93.01.71.21.2-1.1-0.7-0.5-0.8-0.8-0.6-0.5-0.5
Bone: elastic displacement0.30.31.41.20.80.8-0.7-0.3-0.2-0.4-0.4-0.3-0.2-0.2
Bone: elastic work1.62.13.01.7-0.2-0.20.3-1.7-1.6-1.7-1.7-1.7-1.6-1.6
Bone: endosteal estimation3.88.218.7-1.8-4.3-4.34.3-1.9-2.4-1.6-1.8-2.1-2.4-2.4
Bone: endosteal perimeter1.93.911.5-2.9-3.4-3.43.3-0.0-0.50.30.1-0.3-0.5-0.5
Bone: final force5.28.412.83.0-0.3-0.40.6-3.6-3.3-3.5-3.5-3.4-3.4-3.3
Bone: final moment4.77.711.72.8-0.5-0.50.7-3.4-3.2-3.4-3.3-3.3-3.3-3.2
Bone: marrow area3.88.118.2-1.7-4.3-4.34.2-1.9-2.4-1.6-1.8-2.1-2.4-2.4
Bone: maximum diameter1.42.77.2-1.3-2.7-2.72.6-0.8-1.1-0.6-0.7-1.0-1.1-1.1
Bone: maximum force4.47.611.42.6-0.7-0.81.0-3.4-3.2-3.3-3.3-3.3-3.2-3.2
Bone: maximum moment4.07.010.42.3-0.8-0.91.1-3.2-3.1-3.2-3.2-3.1-3.1-3.1
Bone: minimum diameter1.83.28.7-1.5-3.0-3.02.9-0.8-1.2-0.6-0.8-1.1-1.2-1.2
Bone: periosteal estimation3.36.810.7-0.2-3.1-3.23.3-2.4-2.7-2.2-2.3-2.6-2.7-2.7
Bone: periosteal perimeter1.83.06.6-0.7-2.5-2.52.6-1.3-1.6-1.1-1.2-1.4-1.6-1.6
Bone: post-yield work0.71.02.8-1.6-1.7-1.71.60.2-0.10.30.20.0-0.1-0.1
Bone: stiffness1.11.72.61.60.30.2-0.1-1.6-1.4-1.6-1.5-1.4-1.5-1.4
Bone: tissue strength3.73.55.41.8-0.3-0.30.5-2.3-2.2-2.3-2.3-2.2-2.2-2.2
Bone: trabecular number1.72.74.30.32.02.0-2.11.51.71.41.41.61.61.7
Bone: trabecular spacing3.84.96.50.5-2.0-2.02.1-2.4-2.5-2.3-2.3-2.5-2.4-2.5
Bone: trabecular thickness1.21.52.00.01.31.4-1.41.21.31.11.11.31.31.3
Bone: trabecular tissue density1.62.23.21.2-0.6-0.60.6-1.8-1.8-1.8-1.8-1.7-1.7-1.8
Breakpoint value in progressive ratio session1.01.21.7-0.70.60.6-0.61.31.21.31.21.31.21.2
Distance traveled before self-admin0.30.30.8-0.8-0.9-0.90.90.2-0.10.20.1-0.00.0-0.0
Distance traveled after self-admin0.50.61.4-0.5-1.2-1.21.1-0.5-0.6-0.4-0.5-0.7-0.6-0.6
Delta time in closed arm before/after self-admin0.10.10.30.3-0.1-0.20.2-0.4-0.4-0.4-0.4-0.5-0.4-0.4
Delta time in open arm before/after self-admin0.00.00.10.30.20.2-0.2-0.1-0.2-0.1-0.20.0-0.0-0.2
Diff in mean of infusions in LGA sessions3.43.85.1-0.71.71.8-1.92.12.02.12.12.12.32.2
Extinction: sum of active levers before priming0.60.60.80.00.80.8-0.90.70.80.70.80.80.90.8
Active lever presses in extinction session 60.30.30.90.51.01.0-1.00.20.40.10.20.20.30.3
Delta distance traveled before/after self-admin1.01.11.60.7-0.5-0.60.6-1.3-1.2-1.2-1.2-1.2-1.2-1.2
Delta ambulatory time before/after self-admin0.50.50.70.0-0.9-0.90.8-0.7-0.7-0.6-0.7-0.8-0.7-0.8
Time in closed arm before self-admin0.00.00.0-0.00.10.1-0.20.10.20.10.00.00.10.1
Time in closed arm after self-admin0.70.71.41.20.40.4-0.3-1.0-0.8-1.0-0.9-1.0-0.8-0.8
Time in open arm before self-admin0.40.41.0-1.0-0.8-0.80.80.50.40.60.50.40.40.4
Time in open arm after self-admin0.60.71.4-1.0-0.4-0.30.31.00.91.10.91.20.90.8
Sum of active levers in priming session hrs 5-60.50.50.7-0.40.60.6-0.70.70.80.70.70.70.70.8
Time to tail flick, vehicle, before self-admin0.20.20.5-0.7-0.6-0.50.50.30.30.50.30.30.10.3
Time to tail flick, vehicle, after self-admin1.01.03.0-1.7-1.0-1.00.90.90.71.01.00.90.80.8
Time to tail flick, test, before self-admin0.10.10.40.50.60.6-0.6-0.2-0.1-0.2-0.20.2-0.1-0.2
Time to tail flick, test, after self-admin1.01.02.4-1.6-0.7-0.70.71.01.01.21.11.00.91.0
Delta time to tail flick, vehicle, before/after SA0.60.61.0-0.80.20.2-0.30.90.80.80.90.71.00.9
Delta time to tail flick, test, before/after SA0.80.71.1-0.80.10.1-0.11.11.01.01.00.71.01.1
Ambulatory time before self-admin0.00.10.2-0.2-0.4-0.40.4-0.0-0.20.0-0.00.00.0-0.2
Ambulatory time after self-admin0.40.41.2-0.5-1.1-1.11.0-0.3-0.5-0.2-0.3-0.5-0.4-0.5
Total heroin consumption0.00.00.1-0.1-0.0-0.0-0.00.1-0.00.20.20.20.30.1
Area under the delay curve1.71.82.71.3-0.2-0.20.3-1.6-1.6-1.6-1.7-1.6-1.6-1.5
Delay disc. indifference point, 0s delay0.40.50.7-0.0-0.8-0.80.9-0.6-0.8-0.6-0.8-0.7-0.7-0.7
Delay disc. indifference point, 16s delay1.81.84.92.21.31.3-1.1-1.4-1.1-1.4-1.3-1.1-1.1-1.0
Delay disc. indifference point, 2s delay1.92.13.00.6-1.1-1.21.3-1.5-1.7-1.4-1.7-1.7-1.6-1.6
Delay disc. indifference point, 24s delay0.50.41.01.00.40.4-0.3-0.8-0.6-0.8-0.7-0.7-0.7-0.6
Delay disc. indifference point, 4s delay2.93.03.90.5-1.6-1.61.7-1.9-2.0-1.7-1.9-1.9-1.9-1.9
Delay disc. indifference point, 8s delay0.30.30.50.50.0-0.00.1-0.7-0.6-0.7-0.7-0.7-0.7-0.6
Delay discount exponential model param1.61.72.6-1.30.20.2-0.31.61.61.61.61.61.61.4
Delay discount hyperbolic model param1.71.82.7-1.10.40.5-0.61.61.61.61.71.61.61.5
Fecal boli incidents, locomotor time 10.80.81.3-0.60.50.5-0.51.21.01.01.11.01.11.1
Change in fecal boli incidents, locomotor task0.60.60.90.1-0.7-0.70.6-0.9-0.9-0.8-0.7-0.9-0.9-0.9
Time >=10cm from walls, locomotor time 11.01.02.6-0.7-1.6-1.61.5-0.6-0.9-0.4-0.4-0.6-0.6-0.7
Bouts of movement, locomotor time 11.11.22.0-1.4-0.5-0.50.41.31.31.31.21.31.21.1
Total resting periods, locomotor time 10.70.81.7-1.3-0.8-0.80.70.90.80.90.80.80.80.7
Rest time, locomotor task time 10.70.82.4-1.3-1.5-1.51.40.2-0.00.20.2-0.00.1-0.2
Distance moved, locomotor task time 10.60.71.41.20.50.5-0.4-0.9-0.9-0.9-1.0-0.9-0.9-0.7
Vertical activity count, locomotor time 10.40.41.21.10.60.6-0.4-0.5-0.6-0.5-0.6-0.6-0.5-0.4
Time >=10cm from walls, locomotor time 20.20.30.8-0.5-0.9-0.90.9-0.0-0.20.20.1-0.3-0.10.0
Bouts of movement, locomotor time 21.51.64.2-1.0-2.0-2.02.1-0.6-0.9-0.4-0.6-0.9-0.8-0.7
Total resting periods, locomotor time 21.71.85.3-1.4-2.3-2.32.3-0.4-0.7-0.2-0.3-0.7-0.6-0.5
Rest time, locomotor task time 22.02.46.7-2.4-2.6-2.62.30.50.00.80.60.30.40.2
Distance moved, locomotor task time 21.11.33.92.01.51.5-1.2-0.8-0.6-0.9-0.9-0.9-0.7-0.6
Vertical activity count, locomotor time 20.40.51.41.01.21.2-1.0-0.10.0-0.2-0.1-0.1-0.0-0.0
Weight adjusted by age3.33.75.90.6-1.7-1.71.8-2.1-2.0-2.0-2.2-2.2-2.4-2.1
Seeking ratio, delayed vs. immediate footshock0.30.40.60.4-0.4-0.40.4-0.7-0.8-0.7-0.7-0.6-0.7-0.8
Locomotion in novel chamber0.60.71.20.4-0.6-0.60.6-1.0-0.8-0.9-1.1-1.1-1.0-1.0
Locomotion in novel chamber post-restriction0.50.61.00.80.10.0-0.0-0.9-0.8-1.0-1.0-0.9-0.8-0.9
Progressive ratio4.04.67.21.9-0.7-0.81.0-2.7-2.3-2.6-2.5-2.6-2.5-2.5
Food seeking constrained by brief footshock0.00.00.10.10.10.1-0.00.10.20.10.20.20.10.2
Seeking ratio, punishment vs. effort3.64.46.7-1.70.80.8-1.02.62.32.62.52.52.42.5
Run reversals in cocaine runway, females0.50.51.51.21.21.1-1.1-0.3-0.2-0.4-0.3-0.2-0.1-0.1
Run reversals in cocaine runway, males2.02.05.8-1.3-2.4-2.42.4-0.6-0.7-0.3-0.5-0.7-0.8-0.7
Latency to leave start box in cocaine runway0.00.00.10.1-0.1-0.10.2-0.2-0.2-0.2-0.2-0.3-0.2-0.3
Latency to leave start box in cocaine runway, F0.20.20.4-0.6-0.00.00.00.60.50.60.50.40.50.4
Latency to leave start box in cocaine runway, M1.21.11.91.30.10.00.0-1.3-1.2-1.4-1.2-1.2-1.2-1.3
Cd content in liver0.60.71.81.30.80.8-0.7-0.8-0.6-0.9-0.8-0.7-0.7-0.6
Co content in liver1.31.63.61.90.90.9-0.8-1.4-1.1-1.5-1.4-1.2-1.2-1.1
Cu content in liver3.94.77.80.22.72.7-2.82.02.21.81.92.12.12.2
Fe content in liver0.50.62.01.40.80.7-0.6-0.8-0.6-0.8-0.7-0.6-0.6-0.6
K content in liver0.10.10.2-0.30.20.2-0.20.40.40.30.40.50.40.4
Mg content in liver2.12.25.0-2.2-0.9-0.90.61.71.51.71.61.51.41.5
Mn content in liver2.63.09.1-3.0-2.4-2.42.21.20.81.41.20.90.70.8
Na content in liver0.10.10.40.60.50.5-0.4-0.3-0.2-0.3-0.3-0.2-0.1-0.2
Rb content in liver0.91.11.7-0.60.60.7-0.71.11.21.11.21.31.21.2
Se content in liver2.02.46.3-2.5-2.2-2.22.01.10.81.21.10.90.70.8
Sr content in liver0.90.81.8-0.3-1.2-1.21.3-0.7-0.8-0.7-0.8-0.9-0.8-0.8
Zn content in liver0.00.00.1-0.3-0.3-0.30.30.10.10.10.10.10.00.1