Hub : Genes

Epb41l4a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000026050 0.54 0.13 0.0e+00 0.16 0.16 0.16 0.16 1.8e-17 1.5e-17 2.2e-17 3.7e-17
2 BLA gene expression ENSRNOG00000026050 0.14 0.06 8.7e-03 0.03 0.05 0.04 0.03 8.6e-03 1.6e-03 3.0e-03 1.2e-02
3 Brain gene expression ENSRNOG00000026050 0.58 0.09 0.0e+00 0.4 0.42 0.54 0.53 3.4e-39 1.3e-42 6.6e-59 6.1e-57
4 Eye isoform ratio ENSRNOT00000038247 0.48 0.25 2.7e-03 0.05 0.04 -0 0.03 5.8e-02 9.5e-02 3.4e-01 1.4e-01
5 Eye isoform ratio ENSRNOT00000099986 0.52 0.24 6.9e-04 0.08 0.07 0.13 0.11 2.6e-02 3.0e-02 4.6e-03 9.1e-03
6 Eye intron excision ratio chr18:25488305:25493937 0.41 0.18 9.6e-03 0.13 0.04 0.02 0.05 5.2e-03 7.9e-02 1.5e-01 6.2e-02
7 Eye intron excision ratio chr18:25488324:25493937 0.46 0.17 5.4e-03 0.13 0.06 0.01 0.06 5.1e-03 4.7e-02 2.6e-01 4.7e-02
8 IL gene expression ENSRNOG00000026050 0.5 0.18 5.8e-06 0.16 0.17 0.18 0.18 8.9e-05 7.8e-05 4.3e-05 3.7e-05
9 LHb gene expression ENSRNOG00000026050 0.66 0.21 8.5e-05 0.18 0.14 0.12 0.14 5.9e-05 3.4e-04 1.1e-03 3.4e-04
10 Liver gene expression ENSRNOG00000026050 0.15 0.07 1.1e-09 0.09 0.07 0.07 0.08 8.6e-10 1.8e-08 1.4e-08 2.4e-09
11 NAcc gene expression ENSRNOG00000026050 0.06 0.05 4.7e-03 0 0.02 0 0 2.3e-01 1.7e-02 3.1e-01 2.1e-01
12 OFC gene expression ENSRNOG00000026050 0.4 0.2 1.6e-03 0.04 0.09 0.06 0.06 3.4e-02 4.0e-03 1.7e-02 1.5e-02
13 PL gene expression ENSRNOG00000026050 0.28 0.04 0.0e+00 0.2 0.26 0.28 0.25 6.1e-15 3.8e-20 4.3e-21 7.6e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail5.016.135.6-4.54.15.24.5-4.30.1-0.14.63.90.36.03.84.5
BMI without tail5.110.618.3-3.83.94.33.1-3.11.1-1.13.83.30.34.33.43.9
Body weight3.515.039.7-4.03.45.04.9-4.10.4-0.44.43.6-0.36.33.24.4
Epididymis fat weight2.35.411.1-2.31.62.73.3-2.40.7-0.72.93.0-2.22.30.93.1
Glucose4.26.411.8-3.21.92.93.4-3.30.0-0.03.33.0-1.32.71.22.8
Heart weight1.52.17.8-1.41.01.71.8-2.1-0.40.41.30.81.02.81.20.9
Left kidney weight0.10.31.20.2-0.7-0.20.2-0.2-1.11.1-0.1-0.3-0.50.5-0.7-0.1
Right kidney weight0.20.61.60.7-1.0-0.5-0.00.0-1.31.3-0.6-0.80.10.5-0.8-0.6
Tail length0.20.50.9-0.70.80.80.2-0.51.0-1.00.90.80.00.50.60.7
Length with tail0.31.13.5-0.90.81.21.5-1.40.1-0.11.10.70.11.90.80.8
Length without tail0.20.51.6-0.1-0.30.31.2-1.0-0.90.90.2-0.10.01.3-0.10.0
Liver weight, left1.52.47.11.7-2.4-1.70.11.4-0.40.4-1.2-0.6-2.1-1.8-2.7-0.9
Liver weight, right0.91.54.00.8-1.2-1.4-1.31.0-1.31.3-1.0-1.0-0.7-2.0-1.4-1.0
Parametrial fat weight1.73.26.2-2.52.01.81.8-2.4-0.70.72.32.4-0.60.71.42.1
Retroperitoneal fat weight2.68.614.7-3.62.73.53.8-3.2-0.20.23.73.3-1.33.42.23.4
Intraocular pressure3.65.110.7-3.02.22.82.4-2.10.4-0.42.92.40.23.32.02.3
Extensor digitorum longus weight1.56.212.0-2.92.63.12.9-2.8-0.10.12.92.4-0.33.52.42.7
Soleus weight0.72.27.3-1.31.11.72.7-1.50.7-0.71.71.5-0.71.81.11.4
Tibialis anterior weight0.62.26.5-1.41.42.01.4-1.40.8-0.81.61.20.12.51.41.6
Tibia length0.82.35.5-1.61.82.11.1-1.40.4-0.41.61.30.32.31.61.9
Number of licking bursts2.42.84.62.1-2.1-2.0-1.61.7-0.40.4-2.1-2.00.3-1.5-1.8-2.0
Food consumed during 24 hour testing period0.30.41.8-0.10.20.70.7-0.40.2-0.20.30.3-0.51.40.20.9
Times rat made contact with spout0.40.51.2-1.10.90.9-0.4-0.50.4-0.40.90.70.20.70.60.8
Mean time between licks in bursts0.10.10.5-0.5-0.20.20.0-0.3-0.20.20.40.30.20.7-0.3-0.0
Mean num. licks in bursts3.64.47.9-2.82.62.61.3-2.10.5-0.52.62.5-0.22.02.22.5
Std. dev. time between licks in bursts0.30.41.10.2-0.6-0.6-0.2-0.3-1.11.1-0.5-0.40.6-0.3-0.5-0.7
Water consumed over 24 hours0.30.30.80.30.20.2-0.80.30.9-0.9-0.2-0.60.80.60.3-0.0
Indifference point 0 sec1.01.64.20.6-0.4-1.2-2.00.7-1.71.7-1.2-1.40.4-1.7-0.3-1.3
Indifference point AUC2.93.46.02.2-2.0-2.4-1.91.9-0.60.6-2.3-2.00.6-2.1-1.6-2.3
Indifference point function ln k5.88.213.4-3.32.83.73.4-3.20.5-0.53.43.4-0.73.52.33.2
Indifference point function log k5.88.213.4-3.32.83.73.4-3.20.5-0.53.43.4-0.73.52.33.2
Delay discounting total patch changes 0 sec1.11.84.40.8-0.7-1.4-2.10.9-1.71.7-1.4-1.40.3-1.8-0.6-1.4
Delay discounting total patch changes 12 sec5.97.815.62.8-2.5-3.5-4.02.6-1.61.6-3.3-3.20.4-3.4-2.1-3.1
Delay discounting total patch changes 18 sec2.53.38.21.7-1.4-2.2-2.91.7-1.01.0-2.2-2.11.1-2.2-1.1-2.2
Delay discounting total patch changes 24 sec1.41.85.11.1-0.9-1.5-2.31.2-0.80.8-1.6-1.70.9-1.5-0.6-1.6
Delay discounting total patch changes 6 sec2.03.17.41.4-1.3-2.0-2.71.5-1.41.4-2.0-1.90.7-2.3-1.1-1.9
Delay discounting time to switch 0 sec0.60.91.6-1.21.00.90.4-0.71.2-1.21.21.0-0.20.50.70.9
Delay discounting water rate 0 sec0.30.42.6-0.10.10.0-0.2-0.3-1.61.6-0.2-0.20.30.20.1-0.1
Delay discounting water rate 12 sec0.40.61.4-1.20.81.00.3-1.0-0.00.01.00.90.21.10.50.8
Delay discounting water rate 18 sec0.60.71.8-1.00.20.40.4-0.9-1.41.40.71.0-1.2-0.2-0.20.8
Delay discounting water rate 24 sec0.30.42.3-0.4-0.20.30.1-0.2-0.10.10.51.0-1.5-0.4-0.90.8
Delay discounting water rate 6 sec0.10.10.3-0.5-0.10.1-0.1-0.4-0.40.40.40.5-0.3-0.0-0.40.1
Locomotor activity0.81.34.0-0.11.20.8-0.10.22.0-2.00.3-0.51.41.31.70.0
Locomotor testing distance0.20.41.0-0.20.70.50.0-0.30.9-0.90.1-0.30.80.81.00.0
Locomotor testing rearing0.30.41.20.1-0.2-0.6-1.10.1-0.50.5-0.5-0.91.0-0.5-0.0-1.0
Light reinforcement 10.40.74.50.10.1-0.6-2.10.90.6-0.6-0.3-0.70.4-1.3-0.0-0.5
Light reinforcement 20.81.04.00.80.2-0.7-2.01.10.5-0.5-1.1-1.51.0-1.20.5-0.8
Reaction time number correct0.70.92.1-1.40.51.11.1-1.0-0.80.81.21.2-0.31.30.20.9
Reaction time mean minus median1.72.28.2-0.91.60.9-0.50.52.9-2.91.00.61.20.91.80.6
Reaction time mean minus median AUC2.63.47.7-1.82.41.80.1-0.52.8-2.81.91.60.71.22.21.6
Reaction time num false alarms2.12.94.9-2.21.91.81.5-2.1-1.21.21.82.0-0.61.01.52.2
Reaction time num false alarms AUC2.53.66.4-2.42.12.11.9-2.3-0.80.82.12.4-0.91.21.62.5
Reaction time trials correct on left0.70.92.1-1.40.51.11.1-1.0-0.80.81.21.2-0.31.30.20.9
Reaction time trials on left0.71.02.3-1.50.61.21.1-1.0-0.60.61.31.3-0.31.30.31.0
Reaction time mean1.72.34.2-1.62.01.71.1-1.11.4-1.41.71.30.31.62.01.6
Reaction time mean AUC1.62.24.1-1.62.01.60.9-1.11.5-1.51.61.40.11.21.91.6
Median of all reaction times1.72.33.6-1.71.91.81.6-1.60.7-0.71.81.6-0.41.51.81.8
Reaction time omissions0.60.83.7-0.30.90.6-0.10.41.9-1.90.50.50.30.40.90.6
Reaction time false alarm rate1.11.53.1-1.41.61.41.2-1.5-0.30.31.21.5-0.50.61.41.7
Reaction time premature initiation rate6.99.316.84.0-4.1-3.9-2.52.8-1.01.0-3.8-3.30.2-2.5-3.6-3.5
Reaction time premature initiations3.95.611.82.8-3.4-3.0-1.82.0-1.41.4-2.7-2.3-0.2-1.9-3.2-2.7
Std. dev. reaction times2.73.76.5-1.92.52.00.5-0.92.5-2.52.01.51.11.92.51.7
Reaction time trials completed0.71.02.3-1.50.61.21.1-1.0-0.60.61.31.3-0.31.30.31.0
Reaction time trials AUC0.71.12.4-1.60.61.21.1-1.1-0.60.61.41.3-0.21.40.41.0
Social response proportion2.22.44.0-1.42.02.01.4-0.11.7-1.71.61.3-0.21.62.01.7
Social responses0.30.41.90.4-0.1-0.4-0.21.00.2-0.2-0.2-0.2-1.1-1.4-0.20.1
Social time1.01.43.3-1.21.81.60.7-0.70.9-0.91.30.9-0.20.71.71.5
Conditioned locomotion0.30.41.9-0.30.00.1-0.3-0.3-1.41.4-0.0-0.20.20.60.10.0
Cocaine response after cond. corrected1.31.43.4-1.60.91.10.5-1.01.0-1.01.71.9-1.10.50.21.6
Cocaine response after cond. not corrected0.40.41.2-0.90.10.1-0.3-0.20.4-0.40.91.1-1.1-0.5-0.40.7
Cocaine response before conditioning3.54.26.81.9-1.9-2.6-2.51.9-1.61.6-2.4-2.50.8-2.4-1.4-2.5
Saline control response1.31.74.40.9-1.2-1.3-1.10.5-2.12.1-1.4-1.20.2-1.1-1.0-1.4
Condit. Reinf. active minus inactive responses2.73.311.31.2-2.0-2.4-2.01.6-0.80.8-1.4-0.9-1.1-3.4-2.3-1.7
Condit. Reinf. active-inactive response ratio0.40.41.5-0.4-0.4-0.30.3-0.0-0.00.00.50.8-1.2-1.2-1.00.1
Condit. Reinf. active responses5.47.520.72.2-2.7-3.6-3.42.6-1.71.7-2.6-2.1-0.8-4.5-2.8-2.8
Condit. Reinf. inactive responses5.97.413.72.6-2.6-3.4-3.42.8-1.81.8-3.0-2.9-0.1-3.7-2.2-2.9
Condit. Reinf. lever presses2.33.17.41.4-2.2-2.4-1.91.6-0.80.8-1.5-1.1-0.8-2.7-2.3-1.9
Condit. Reinf. lever reinforcers received4.97.019.92.1-2.6-3.5-3.22.5-1.51.5-2.5-2.0-0.8-4.5-2.8-2.7
Pavlov. Cond. lever latency1.11.54.6-0.41.21.51.3-0.71.5-1.50.80.30.82.11.51.0
Pavlov. Cond. magazine entry latency0.30.30.90.3-0.7-0.6-0.30.5-0.10.1-0.10.0-1.0-0.9-0.9-0.3
Pavlov. Cond. change in total contacts1.11.65.01.0-1.3-1.7-1.21.20.3-0.3-1.1-0.9-0.2-2.2-1.3-1.6
Pavlov. Cond. index score0.81.13.40.8-1.3-1.4-0.80.9-0.30.3-0.7-0.4-0.9-1.8-1.5-1.0
Pavlov. Cond. latency score0.91.23.31.0-1.4-1.4-0.60.9-0.60.6-0.9-0.5-0.9-1.8-1.5-1.1
Pavlov. Cond. lever contacts1.31.95.50.5-1.6-1.7-1.50.9-1.31.3-0.8-0.3-1.1-2.3-1.9-1.1
Pavlov. Cond. magazine entry number0.80.92.5-1.01.11.31.0-1.10.2-0.20.90.70.51.61.01.0
Pavlov. Cond. intertrial magazine entries0.10.10.40.10.20.2-0.2-0.10.7-0.70.00.10.70.40.3-0.0
Pavlov. Cond. lever-magazine prob. diff.0.91.13.50.8-1.4-1.4-0.81.0-0.10.1-0.7-0.4-0.8-1.9-1.5-1.0
Pavlov. Cond. response bias1.42.06.20.7-1.5-1.8-1.81.2-1.01.0-1.1-0.7-0.7-2.5-1.7-1.3
Conditioned reinforcement - actives0.20.21.0-0.3-0.1-0.10.30.00.00.00.10.7-1.0-1.0-0.60.3
Conditioned reinforcement - inactives0.00.00.1-0.30.0-0.1-0.30.00.00.0-0.30.10.1-0.1-0.10.1
Conditioned locomotion0.50.61.80.6-1.0-0.9-0.50.00.00.0-0.6-0.1-1.1-1.4-1.3-0.4
Intermittent access intake day 1-15 change0.10.10.40.3-0.30.00.60.00.00.0-0.3-0.10.20.7-0.1-0.1
Intermittent access intake escalation0.10.10.20.4-0.4-0.20.20.00.00.0-0.4-0.20.20.4-0.2-0.2
Intermittent access intake escalation 20.20.10.70.30.00.20.60.00.00.0-0.1-0.30.80.80.3-0.1
Intermitt. access day 1 inactive lever presses0.91.03.21.0-1.8-1.2-0.20.00.00.0-0.9-0.7-0.9-0.8-1.8-1.0
Intermitt. access day 15 inactive lever presses0.10.10.5-0.1-0.20.0-0.40.00.00.00.00.3-0.7-0.1-0.50.4
Intermitt. access escalation Index0.40.31.50.2-0.9-0.11.00.00.00.00.20.3-1.20.3-0.90.0
Intermittent access day 1 total infusions0.80.94.00.2-1.1-1.1-0.60.00.00.0-0.50.3-1.5-2.0-1.6-0.3
Intermittent access day 15 total infusions0.60.62.30.2-1.0-0.9-0.60.00.00.0-0.50.3-1.2-1.5-1.5-0.2
Intermittent access terminal intake (last 3 days)0.20.20.90.1-0.4-0.5-0.40.00.00.0-0.40.2-0.4-1.0-0.7-0.1
Intermittent access total infusions0.50.62.2-0.2-0.7-0.6-0.10.00.00.0-0.20.8-1.5-1.5-1.30.2
Intermittent access day 1 locomotion0.80.83.4-0.0-1.0-0.70.00.00.00.0-0.10.7-1.9-1.6-1.60.1
Intermittent access day 15 total locomotion0.70.73.4-0.2-0.80.21.20.00.00.00.71.2-1.80.0-1.40.6
Intermittent access total locomotion0.60.73.4-0.3-0.6-0.01.10.00.00.00.51.2-1.8-0.7-1.30.6
Intermittent access standard deviation0.30.30.80.6-0.8-0.60.90.00.00.0-0.5-0.2-0.1-0.4-0.7-0.6
Cocaine induced anxiety0.20.21.20.1-0.7-0.30.60.00.00.0-0.00.2-1.1-0.3-0.80.1
Post-drug Anxiety1.71.84.11.8-2.0-1.8-0.40.00.00.0-2.0-1.70.3-0.8-1.5-1.8
Baseline Anxiety1.11.13.51.3-0.6-0.9-1.10.00.00.0-1.4-1.61.90.10.0-1.5
Lifetime Intake0.60.73.2-0.6-0.2-0.20.10.00.00.00.41.3-1.8-1.4-1.00.7
Incentive Sensitization - Responses0.20.20.8-0.2-0.6-0.30.20.00.00.0-0.20.4-0.6-0.5-0.90.0
Incentive Sensitization - Breakpoint0.10.10.6-0.3-0.5-0.20.20.00.00.0-0.10.5-0.6-0.4-0.80.1
Progressive ratio test 1 active lever presses0.50.63.1-0.5-0.4-0.10.10.00.00.00.41.0-1.8-1.1-1.10.6
Progressive ratio test 1 breakpoint0.60.63.0-0.6-0.2-0.00.20.00.00.00.51.1-1.7-1.0-1.00.7
Progressive ratio test 1 inactive lever presses0.60.62.9-0.2-0.7-0.6-0.50.00.00.0-0.10.5-1.7-1.5-1.30.3
Progressive ratio test 2 active lever presses1.01.05.2-0.7-0.5-0.20.30.00.00.00.41.5-2.3-1.4-1.40.8
Progressive ratio test 2 breakpoint0.80.94.4-0.6-0.6-0.20.60.00.00.00.31.4-2.1-1.2-1.50.7
Progressive ratio test 2 inactive lever presses1.41.66.10.3-1.8-1.10.30.00.00.0-0.50.6-2.5-1.8-2.5-0.1
Total sessions with >9 infusions0.80.92.4-1.00.50.81.50.00.00.01.11.6-1.40.1-0.11.4
Short access day 1 total inactive lever presses1.92.17.00.6-1.8-1.5-0.90.00.00.0-0.60.2-2.5-2.6-2.5-0.4
Short access day 10 total inactive lever presses0.70.81.71.0-1.3-1.1-1.10.00.00.0-1.1-1.1-0.0-0.6-1.1-1.1
Short access day 1 total infusions1.81.96.0-1.71.00.90.70.00.00.01.82.2-2.4-1.4-0.11.8
Short access day 10 total infusions0.20.20.90.0-0.5-0.5-0.10.00.00.0-0.30.3-0.8-0.9-0.80.0
Short access total infusions0.50.61.9-0.90.40.10.00.00.00.00.71.2-1.4-1.3-0.30.9
Short access day 1 locomotion2.22.46.8-1.91.21.51.50.00.00.02.12.6-2.20.10.22.3
Short access day 10 total locomotion0.50.64.6-0.2-0.00.62.20.00.00.00.50.6-0.21.20.00.5
Short access total locomotion0.50.52.0-0.60.30.51.40.00.00.00.71.2-0.90.1-0.10.9
Compulsive drug intake2.12.14.8-1.62.22.01.00.00.00.01.91.40.71.62.01.5
One hour access (0.3 mA shock)0.70.92.7-1.41.11.00.50.00.00.01.01.6-1.0-0.10.41.4
One hour access (shock baseline)0.60.72.20.2-1.0-0.9-0.10.00.00.0-0.70.3-1.5-1.4-1.5-0.1
Number of responses in last shaping day0.70.72.90.0-0.7-0.8-1.20.00.00.0-0.20.3-1.3-1.7-1.4-0.2
Context. condit. distance diff. score0.40.51.3-0.91.20.9-0.4-0.8-0.20.20.50.40.10.61.00.8
Locomotion velocity, session 11.31.45.01.1-1.9-1.00.80.50.1-0.1-0.5-0.0-2.1-1.0-2.2-0.4
Locomotion distance, session 10.10.10.40.2-0.3-0.1-0.00.30.4-0.40.10.0-0.7-0.3-0.50.1
Locomotion velocity, session 20.30.41.00.1-0.6-0.10.90.21.0-1.00.50.3-0.60.4-0.7-0.0
Locomotion distance, session 20.50.71.30.5-1.0-1.1-0.90.8-0.60.6-0.5-0.7-0.3-1.1-1.0-0.9
Locomotion velocity, session 30.70.81.8-1.31.01.00.4-0.70.6-0.61.31.1-0.80.60.61.2
Locomotion distance, session 30.50.51.1-0.71.00.7-0.6-0.31.0-1.00.70.50.00.40.90.7
Stereotopy head waving bouts, day 31.11.42.50.9-1.0-1.6-1.41.2-0.50.5-1.3-1.50.5-1.5-0.8-1.5
Stereotopy head waving duration, day 30.20.21.0-0.60.3-0.10.2-0.2-1.01.00.2-0.10.1-0.40.3-0.1
Locomotion velocity, session 70.20.31.2-0.50.40.40.3-0.6-0.30.30.40.40.51.10.60.2
Locomotion distance, session 70.40.51.8-0.50.60.1-0.7-0.5-0.90.9-0.1-0.31.30.60.9-0.3
Stereotopy head waving bouts, day 70.20.21.40.30.30.41.2-0.30.1-0.1-0.00.1-0.10.50.40.4
Stereotopy head waving duration, day 70.10.10.50.3-0.00.00.70.0-0.30.3-0.2-0.1-0.20.00.10.2
Locomotion velocity, session 81.01.24.6-0.80.90.80.7-0.22.1-2.11.31.1-0.70.10.51.0
Locomotion distance, session 80.20.30.6-0.80.70.5-0.4-0.30.5-0.50.70.5-0.6-0.10.30.7
Degree of sensitization distance0.60.72.1-0.40.20.10.4-0.7-1.51.5-0.1-0.41.40.90.6-0.4
Degree of sensitization stereotypy0.20.31.31.2-0.3-0.10.80.40.5-0.5-0.6-0.4-0.30.1-0.10.1
Condit. Reinf. active minus inactive responses1.31.52.71.5-1.1-1.4-1.51.5-0.60.6-1.5-1.2-0.2-1.7-1.0-1.1
Condit. Reinf. active-inactive response ratio0.60.61.80.10.3-0.3-1.10.2-1.31.3-0.6-0.81.0-0.30.6-0.4
Condit. Reinf. active responses2.83.47.12.0-2.3-2.2-1.82.2-0.40.4-1.7-1.1-1.5-2.7-2.6-1.4
Condit. Reinf. inactive responses3.44.010.12.1-2.8-2.4-1.52.20.3-0.3-1.6-1.1-1.9-2.7-3.2-1.6
Incentive salience index mean1.92.34.61.8-1.7-1.8-1.31.6-0.90.9-1.7-1.3-0.7-2.1-1.7-1.3
Condit. Reinf. lever presses1.31.73.71.5-1.5-1.6-1.11.0-1.01.0-1.6-1.3-0.3-1.9-1.4-1.2
Time in familiar zone, hab. session 10.20.20.70.6-0.10.20.2-0.3-0.90.9-0.4-0.30.30.70.1-0.0
Time in novel zone, hab. session 10.50.51.5-0.50.6-0.1-0.80.61.2-1.20.2-0.30.8-0.40.7-0.3
Total zone transitions, hab. session 11.21.75.40.8-1.00.31.80.32.3-2.30.41.0-1.70.2-1.30.5
Total locomotion distance, hab. session 11.21.74.11.4-1.6-0.90.31.01.8-1.8-0.50.3-1.8-1.5-2.0-0.3
Locomotion velocity, hab. session 11.42.05.31.3-1.7-0.90.30.91.6-1.6-0.40.5-2.2-1.8-2.3-0.2
Time in familiar zone, hab. session 21.71.75.80.20.4-0.6-2.40.3-2.32.3-1.0-1.21.5-0.50.7-0.7
Time in novel zone, hab. session 21.81.84.9-0.5-0.20.62.2-0.32.2-2.21.21.5-1.60.4-0.60.9
Total zone transitions, hab. session 20.30.42.40.00.00.40.20.61.5-1.50.40.4-0.30.0-0.20.4
Total locomotion distance, hab. session 20.20.31.20.1-0.3-0.3-0.90.60.5-0.5-0.00.1-0.6-1.1-0.70.0
Locomotion velocity, hab. session 20.20.31.0-0.0-0.3-0.1-0.50.40.7-0.70.20.4-0.9-1.0-0.80.2
Novel to familiar place preference ratio4.64.89.6-2.63.02.61.8-2.31.0-1.02.31.61.02.53.12.1
Novelty place preference4.95.19.9-2.63.12.72.0-2.31.0-1.02.31.80.92.73.12.2
Time in novel zone, NPP test4.75.09.9-2.73.12.61.8-2.31.0-1.02.31.71.12.63.12.1
Total zone transitions, NPP test1.31.95.41.5-2.1-1.4-0.11.60.9-0.9-0.9-0.7-1.4-1.5-2.3-1.0
Total locomotion distance, NPP test1.62.26.21.7-2.1-1.6-0.91.30.2-0.2-1.2-0.6-1.7-2.3-2.5-1.0
Locomotion velocity, NPP test1.72.46.41.8-2.1-1.7-1.01.40.3-0.3-1.3-0.7-1.6-2.4-2.5-1.1
Pavlov. Cond. lever latency1.41.84.9-2.22.01.2-0.2-1.7-0.30.31.41.01.21.02.00.9
Pavlov. Cond. magazine entry latency0.81.02.81.3-0.6-0.7-0.30.4-1.31.3-1.4-1.70.9-0.1-0.1-1.2
Pavlov. Cond. change in total contacts0.70.72.31.5-0.8-0.70.11.00.7-0.7-1.1-1.20.4-0.2-0.4-0.9
Pavlov. Cond. index score0.81.03.21.8-1.3-1.00.20.9-0.60.6-1.3-1.1-0.3-0.6-1.1-0.9
Pavlov. Cond. latency score0.60.72.51.6-1.2-0.70.40.8-0.20.2-1.1-0.8-0.5-0.5-1.0-0.6
Pavlov. Cond. lever contacts1.92.35.32.3-2.2-1.6-0.01.6-0.60.6-1.7-1.4-1.0-1.4-2.0-1.2
Pavlov. Cond. magazine entry number0.50.61.7-1.30.60.60.3-0.40.7-0.71.21.3-0.60.20.20.9
Pavlov. Cond. intertrial magazine entries1.41.74.91.4-2.0-1.5-0.61.50.7-0.7-1.0-0.4-1.1-1.6-2.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.03.01.7-1.3-1.0-0.10.9-0.60.6-1.3-1.3-0.2-0.7-1.0-1.0
Pavlov. Cond. response bias1.21.53.61.9-1.5-1.2-0.31.0-0.90.9-1.6-1.6-0.2-0.8-1.2-1.3
Bone: apparent density0.71.23.92.0-1.2-0.9-1.01.50.4-0.4-1.8-1.30.0-0.5-0.9-0.7
Bone surface1.22.13.61.9-1.9-1.6-1.61.6-0.30.3-1.9-1.7-0.1-1.1-1.7-1.5
Bone volume1.22.14.22.1-1.9-1.5-1.31.80.0-0.0-1.8-1.5-0.5-1.0-1.7-1.3
Bone: connectivity density1.72.76.32.5-1.7-1.8-1.82.00.1-0.1-2.5-1.80.3-1.5-1.5-1.4
Bone: cortical apparent density1.01.32.21.5-1.2-1.4-0.91.3-0.30.3-1.5-1.4-0.0-1.4-0.9-1.3
Bone: cortical area2.33.46.32.0-1.4-1.9-2.52.51.5-1.5-2.0-2.50.6-1.5-1.0-2.1
Bone: cortical porosity0.50.52.1-0.9-0.00.41.0-0.3-0.40.40.90.8-1.50.3-0.30.7
Bone: cortical porosity0.40.41.3-1.00.10.40.9-0.5-0.40.41.00.7-1.10.2-0.20.6
Bone: cortical thickness1.62.76.31.8-0.7-1.3-2.32.11.4-1.4-1.9-2.51.5-0.7-0.1-1.7
Bone: cortical thickness0.40.51.50.40.1-0.1-1.00.71.2-1.2-0.4-0.60.80.10.3-0.3
Bone: cortical tissue density0.91.22.11.4-1.3-1.4-0.71.2-0.40.4-1.4-1.3-0.1-1.4-1.0-1.2
Bone: elastic displacement1.31.52.8-1.51.21.41.3-1.20.7-0.71.71.5-0.71.00.81.6
Bone: elastic work1.11.42.6-1.20.91.41.5-1.00.1-0.11.51.4-1.41.10.51.6
Bone: endosteal estimation0.61.22.30.7-1.4-1.5-1.31.20.0-0.0-0.6-0.9-0.7-1.5-1.5-1.4
Bone: endosteal perimeter0.10.30.5-0.2-0.4-0.6-0.50.30.7-0.70.1-0.3-0.3-0.7-0.6-0.7
Bone: final force1.11.83.11.6-1.1-1.3-1.61.81.2-1.2-1.4-1.80.2-1.1-0.8-1.4
Bone: final moment0.81.32.51.3-1.1-1.1-1.21.61.1-1.1-1.1-1.4-0.3-1.1-0.9-1.2
Bone: marrow area0.51.01.90.6-1.2-1.4-1.31.00.1-0.1-0.6-0.8-0.6-1.4-1.3-1.3
Bone: maximum diameter2.03.76.41.7-1.9-2.3-2.52.40.9-0.9-1.7-2.1-0.4-2.4-1.9-2.2
Bone: maximum force0.61.01.91.2-0.8-0.8-1.01.31.0-1.0-1.1-1.40.3-0.5-0.5-1.1
Bone: maximum moment0.40.61.21.0-0.8-0.7-0.61.10.9-0.9-0.8-1.0-0.2-0.4-0.6-0.8
Bone: minimum diameter0.71.42.50.9-1.4-1.6-1.51.2-0.50.5-1.1-1.2-0.3-1.4-1.3-1.5
Bone: periosteal estimation1.12.34.51.4-1.4-1.8-2.11.90.8-0.8-1.4-1.90.0-1.5-1.2-2.0
Bone: periosteal perimeter0.61.01.80.7-0.9-1.2-1.31.10.9-0.9-0.7-1.2-0.0-1.2-0.8-1.3
Bone: post-yield work0.40.51.01.0-0.8-0.7-0.40.8-0.50.5-0.9-0.80.1-0.6-0.6-0.8
Bone: stiffness1.01.53.21.6-1.2-1.2-1.31.60.6-0.6-1.5-1.80.4-0.8-0.8-1.5
Bone: tissue strength0.20.20.5-0.70.50.40.1-0.6-0.50.50.40.2-0.10.40.50.3
Bone: trabecular number0.71.03.21.8-1.2-0.9-0.81.3-0.30.3-1.6-1.1-0.1-0.5-1.1-0.6
Bone: trabecular spacing0.10.20.7-0.60.40.0-0.2-0.40.3-0.30.2-0.20.90.30.5-0.3
Bone: trabecular thickness0.81.02.91.7-1.1-1.0-0.81.3-0.10.1-1.5-1.1-0.2-0.4-0.9-0.8
Bone: trabecular tissue density0.70.93.4-0.20.70.60.4-0.11.8-1.80.3-0.31.01.31.10.1
Breakpoint value in progressive ratio session0.00.00.10.1-0.10.00.30.00.00.00.10.1-0.0-0.2-0.2-0.2
Distance traveled before self-admin0.60.62.6-0.71.50.80.00.00.00.00.60.40.90.51.60.5
Distance traveled after self-admin0.50.62.8-0.70.40.0-0.60.00.00.00.70.9-1.5-1.7-0.40.5
Delta time in closed arm before/after self-admin1.21.24.1-0.90.10.91.80.00.00.01.31.4-2.00.7-0.21.4
Delta time in open arm before/after self-admin1.91.84.91.8-1.1-1.3-1.00.00.00.0-2.0-2.22.00.3-0.2-1.9
Diff in mean of infusions in LGA sessions0.91.02.8-1.20.61.10.80.00.00.01.51.7-1.60.3-0.01.5
Extinction: sum of active levers before priming0.00.00.10.1-0.2-0.00.30.00.00.00.10.2-0.2-0.1-0.3-0.2
Active lever presses in extinction session 61.21.13.01.0-1.0-1.3-1.70.00.00.0-1.3-1.20.4-1.4-0.9-1.5
Delta distance traveled before/after self-admin1.61.77.6-0.6-0.4-0.6-1.80.00.00.00.60.9-2.6-2.8-1.60.5
Delta ambulatory time before/after self-admin1.21.36.7-0.6-0.3-0.5-1.70.00.00.00.50.8-2.0-2.6-1.40.4
Time in closed arm before self-admin0.30.31.9-0.20.40.70.60.00.00.00.40.20.41.40.50.4
Time in closed arm after self-admin0.50.51.4-0.60.50.91.20.00.00.00.80.8-0.51.00.51.0
Time in open arm before self-admin0.70.72.0-1.30.70.50.00.00.00.01.21.3-1.4-0.8-0.01.2
Time in open arm after self-admin1.41.63.21.7-1.8-1.5-0.80.00.00.0-1.7-1.70.7-0.3-1.3-1.8
Sum of active levers in priming session hrs 5-60.40.42.5-0.40.7-0.2-1.20.00.00.00.30.20.3-1.60.3-0.1
Time to tail flick, vehicle, before self-admin0.80.82.90.40.8-0.3-1.40.00.00.0-0.9-1.31.7-0.11.4-0.6
Time to tail flick, vehicle, after self-admin0.10.10.40.2-0.1-0.40.20.00.00.0-0.4-0.40.6-0.2-0.0-0.5
Time to tail flick, test, before self-admin0.10.10.3-0.1-0.00.20.50.00.00.00.20.2-0.40.0-0.00.2
Time to tail flick, test, after self-admin0.20.21.50.2-0.1-0.4-0.80.00.00.0-0.2-0.3-0.7-1.2-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.21.10.1-0.8-0.20.60.00.00.00.20.4-0.5-0.1-1.0-0.2
Delta time to tail flick, test, before/after SA0.00.00.2-0.10.4-0.0-0.20.00.00.00.1-0.10.1-0.20.50.0
Ambulatory time before self-admin0.60.62.5-0.51.30.80.00.00.00.00.40.21.20.81.60.3
Ambulatory time after self-admin0.40.51.2-0.90.90.3-0.90.00.00.00.80.8-0.8-1.10.20.6
Total heroin consumption0.91.12.8-1.31.71.40.60.00.00.01.41.2-0.10.51.41.3
Area under the delay curve0.91.05.4-0.21.2-0.1-2.30.00.00.0-0.4-0.81.6-0.71.4-0.2
Delay disc. indifference point, 0s delay0.50.52.2-0.20.90.1-1.50.00.00.0-0.0-0.61.4-0.11.1-0.2
Delay disc. indifference point, 16s delay1.31.36.00.50.4-0.9-2.40.00.00.0-1.2-1.51.8-1.00.8-1.0
Delay disc. indifference point, 2s delay0.40.41.6-0.31.10.4-0.80.00.00.00.2-0.21.20.21.30.2
Delay disc. indifference point, 24s delay0.80.82.8-0.71.70.8-1.10.00.00.00.60.51.20.21.50.8
Delay disc. indifference point, 4s delay0.20.20.7-0.10.6-0.0-0.80.00.00.0-0.1-0.30.8-0.30.6-0.1
Delay disc. indifference point, 8s delay1.21.27.9-0.41.50.0-2.80.00.00.0-0.1-0.71.5-0.81.50.0
Delay discount exponential model param0.91.05.60.1-1.10.22.40.00.00.00.50.9-1.60.7-1.20.3
Delay discount hyperbolic model param0.80.95.1-0.0-0.90.32.30.00.00.00.50.9-1.60.8-1.10.4
Fecal boli incidents, locomotor time 10.30.30.9-0.90.60.50.60.00.00.00.90.8-0.6-0.20.20.6
Change in fecal boli incidents, locomotor task0.50.43.4-0.5-0.10.20.10.00.00.00.40.8-1.8-0.5-0.40.9
Time >=10cm from walls, locomotor time 10.80.82.5-1.10.61.00.40.00.00.01.01.3-1.60.40.21.4
Bouts of movement, locomotor time 10.30.33.10.10.2-0.2-1.80.00.00.0-0.3-0.10.2-0.8-0.1-0.1
Total resting periods, locomotor time 10.20.32.6-0.10.4-0.0-1.60.00.00.0-0.10.1-0.3-0.70.10.3
Rest time, locomotor task time 10.20.20.6-0.50.40.5-0.20.00.00.00.50.5-0.70.50.10.8
Distance moved, locomotor task time 11.21.33.41.7-1.5-1.20.20.00.00.0-1.5-1.81.2-0.0-0.7-1.8
Vertical activity count, locomotor time 10.80.81.81.3-0.8-0.50.80.00.00.0-1.2-1.31.21.00.2-1.1
Time >=10cm from walls, locomotor time 21.21.37.3-0.70.21.22.70.00.00.00.91.2-0.91.80.31.0
Bouts of movement, locomotor time 20.20.21.10.2-0.0-0.4-1.00.00.00.0-0.7-0.30.5-0.30.1-0.3
Total resting periods, locomotor time 20.10.10.80.10.1-0.2-0.90.00.00.0-0.5-0.10.5-0.10.1-0.0
Rest time, locomotor task time 22.22.65.1-1.82.22.20.70.00.00.02.11.80.21.91.92.1
Distance moved, locomotor task time 21.61.85.01.9-1.6-1.4-0.20.00.00.0-2.0-2.21.30.1-0.6-2.1
Vertical activity count, locomotor time 21.51.75.01.9-1.5-1.4-0.20.00.00.0-2.2-2.11.00.0-0.6-1.8
Weight adjusted by age0.91.03.1-0.70.91.21.60.00.00.00.90.7-0.21.81.11.1
Seeking ratio, delayed vs. immediate footshock2.02.34.81.9-2.2-2.0-0.70.00.00.0-1.8-1.5-0.6-1.9-2.0-1.8
Locomotion in novel chamber0.70.92.0-1.31.00.90.30.00.00.01.41.4-1.4-0.30.41.4
Locomotion in novel chamber post-restriction0.30.32.10.30.20.1-0.10.00.00.0-0.4-0.61.41.00.7-0.3
Progressive ratio0.81.02.8-1.31.71.10.50.00.00.01.31.3-0.00.01.21.2
Food seeking constrained by brief footshock0.10.21.1-0.10.40.1-0.10.00.00.00.1-0.31.10.10.6-0.4
Seeking ratio, punishment vs. effort0.60.71.71.0-1.1-0.9-0.70.00.00.0-1.1-1.30.70.2-0.6-1.3
Run reversals in cocaine runway, females0.20.20.70.00.60.1-0.70.00.00.0-0.2-0.50.50.00.9-0.0
Run reversals in cocaine runway, males0.10.10.50.30.30.10.10.00.00.0-0.4-0.20.70.20.6-0.1
Latency to leave start box in cocaine runway0.30.42.20.20.3-0.4-1.50.00.00.0-0.6-1.00.7-0.40.5-0.4
Latency to leave start box in cocaine runway, F1.01.12.91.0-0.7-1.1-1.50.00.00.0-1.4-1.71.5-0.3-0.3-1.4
Latency to leave start box in cocaine runway, M1.41.33.3-1.51.81.40.20.00.00.01.41.3-1.00.31.51.7
Cd content in liver0.20.20.70.0-0.6-0.4-0.10.30.1-0.10.00.2-0.7-0.8-0.8-0.1
Co content in liver0.91.13.11.5-1.7-0.90.51.20.3-0.3-0.90.0-1.2-0.6-1.8-0.4
Cu content in liver2.02.54.91.7-0.9-1.7-2.22.11.6-1.6-1.5-1.50.3-2.0-0.6-1.4
Fe content in liver0.81.02.81.0-0.4-1.0-1.40.7-0.30.3-1.3-1.71.3-0.50.1-1.3
K content in liver2.02.04.32.1-1.8-1.5-0.41.81.1-1.1-1.5-0.8-0.9-1.7-1.8-1.2
Mg content in liver1.91.94.41.8-1.5-1.6-1.31.90.3-0.3-1.5-0.8-0.9-2.1-1.7-1.0
Mn content in liver0.30.41.40.1-0.7-0.20.4-0.5-1.21.2-0.10.3-0.50.0-0.8-0.0
Na content in liver0.30.30.60.5-0.7-0.60.10.0-0.70.7-0.5-0.1-0.6-0.8-0.7-0.3
Rb content in liver4.25.310.53.2-2.9-2.7-1.92.40.0-0.0-2.8-2.2-0.0-2.4-2.7-2.5
Se content in liver0.91.02.51.6-1.2-1.2-0.70.90.0-0.0-1.4-1.30.8-0.4-0.8-1.3
Sr content in liver0.70.73.20.30.2-0.3-0.61.01.8-1.8-0.2-0.40.2-0.60.3-0.4
Zn content in liver2.12.46.21.7-0.7-1.1-1.72.52.3-2.3-1.4-1.3-0.0-1.4-0.5-0.9