Plb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000026037 0.74 0.19 2.1e-07 0.06 0.06 0.06 0.06 4.3e-07 9.6e-07 5.8e-07 3.5e-07
2 BLA intron excision ratio chr6:24090778:24092431 0.08 0.08 1.2e-03 0.06 0.05 0.06 0.06 3.3e-04 7.5e-04 3.3e-04 6.2e-04
3 BLA intron excision ratio chr6:24090778:24097763 0.08 0.07 1.7e-03 0.06 0.05 0.06 0.05 5.0e-04 1.1e-03 4.2e-04 8.8e-04
4 Brain gene expression ENSRNOG00000026037 0.04 0.04 1.1e-03 0.03 0.03 0.04 0.03 4.7e-04 9.0e-04 3.4e-04 3.9e-04
5 Brain intron excision ratio chr6:24090778:24092431 0.03 0.03 1.0e-03 0.02 0.03 0.03 0.02 3.5e-03 8.5e-04 1.8e-03 2.5e-03
6 Brain intron excision ratio chr6:24090778:24097763 0.03 0.03 1.6e-03 0.02 0.03 0.02 0.02 5.0e-03 1.4e-03 3.2e-03 4.5e-03
7 PL intron excision ratio chr6:24090778:24097763 0.04 0.04 7.8e-03 0.02 0.02 0.01 0.02 1.9e-02 7.5e-03 7.4e-02 8.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.31.01.30.9-1.01.0-0.7-1.11.11.1
BMI without tail0.20.50.80.5-0.90.9-0.3-0.70.70.7
Body weight1.66.67.42.5-2.42.3-2.5-2.72.72.7
Epididymis fat weight14.934.836.86.1-5.75.6-6.0-6.06.06.0
Glucose0.81.22.01.3-1.31.4-1.0-0.80.90.9
Heart weight8.712.514.73.5-3.13.0-3.6-3.83.83.8
Left kidney weight0.10.20.5-0.60.6-0.70.10.2-0.2-0.2
Right kidney weight0.41.01.70.9-0.60.5-1.3-1.21.21.2
Tail length0.20.71.00.8-1.01.0-0.9-0.80.80.8
Length with tail1.45.06.22.3-2.02.0-2.5-2.32.32.3
Length without tail0.61.32.21.3-0.80.7-1.5-1.21.21.3
Liver weight, left2.03.24.31.8-1.81.8-2.1-1.61.61.7
Liver weight, right9.515.817.24.0-3.83.8-4.2-4.04.04.0
Parametrial fat weight5.611.011.43.4-3.43.4-3.1-3.43.43.3
Retroperitoneal fat weight21.470.973.18.5-8.38.2-8.3-8.58.58.5
Intraocular pressure3.14.44.92.1-2.01.9-2.1-2.22.22.2
Extensor digitorum longus weight4.819.320.3-4.44.3-4.34.54.4-4.4-4.4
Soleus weight5.516.117.7-4.03.9-3.94.24.0-4.0-4.1
Tibialis anterior weight4.314.715.8-3.93.9-3.94.03.7-3.7-3.8
Tibia length2.77.58.22.8-2.52.5-2.7-2.92.92.9
Number of licking bursts0.20.30.4-0.50.6-0.60.40.5-0.5-0.5
Food consumed during 24 hour testing period0.40.40.9-0.70.9-0.90.40.5-0.5-0.5
Times rat made contact with spout2.62.93.2-1.61.8-1.81.61.7-1.7-1.7
Mean time between licks in bursts2.43.33.91.9-1.71.7-2.0-1.81.81.8
Mean num. licks in bursts0.10.10.2-0.30.3-0.30.40.3-0.3-0.3
Std. dev. time between licks in bursts0.00.00.10.2-0.10.1-0.2-0.30.30.3
Water consumed over 24 hours1.51.82.4-1.21.5-1.51.01.3-1.3-1.3
Indifference point 0 sec0.20.40.50.5-0.60.6-0.5-0.70.70.7
Indifference point AUC1.11.31.6-1.11.0-0.91.21.3-1.3-1.3
Indifference point function ln k0.00.00.10.3-0.20.2-0.0-0.10.10.1
Indifference point function log k0.00.00.10.3-0.20.2-0.0-0.10.10.1
Delay discounting total patch changes 0 sec0.10.20.30.4-0.50.4-0.3-0.50.50.5
Delay discounting total patch changes 12 sec0.60.80.90.9-0.80.8-0.9-1.01.00.9
Delay discounting total patch changes 18 sec0.00.00.10.0-0.10.1-0.0-0.30.20.2
Delay discounting total patch changes 24 sec1.21.52.01.2-1.01.0-1.4-1.31.31.3
Delay discounting total patch changes 6 sec0.00.00.00.00.0-0.00.1-0.20.20.2
Delay discounting time to switch 0 sec0.20.30.4-0.60.6-0.60.40.4-0.4-0.4
Delay discounting water rate 0 sec0.10.10.20.4-0.40.4-0.2-0.30.30.3
Delay discounting water rate 12 sec1.42.22.61.4-1.41.3-1.6-1.51.51.5
Delay discounting water rate 18 sec0.20.30.50.3-0.30.2-0.7-0.70.70.7
Delay discounting water rate 24 sec2.02.73.11.6-1.71.8-1.5-1.71.71.7
Delay discounting water rate 6 sec1.31.82.11.3-1.21.2-1.4-1.41.41.4
Locomotor activity0.00.00.1-0.20.1-0.20.20.1-0.1-0.1
Locomotor testing distance0.71.21.6-1.21.2-1.31.10.9-0.9-1.0
Locomotor testing rearing0.50.81.0-0.90.7-0.71.00.9-0.9-0.9
Light reinforcement 14.07.49.1-2.82.4-2.43.02.8-2.8-2.8
Light reinforcement 23.34.44.9-2.22.0-1.92.12.1-2.1-2.1
Reaction time number correct0.81.11.3-1.11.1-1.20.91.0-1.0-1.0
Reaction time mean minus median0.00.10.2-0.20.3-0.30.40.0-0.1-0.1
Reaction time mean minus median AUC0.00.00.1-0.00.2-0.30.2-0.10.10.0
Reaction time num false alarms0.30.40.5-0.70.5-0.50.70.7-0.7-0.7
Reaction time num false alarms AUC0.60.80.9-1.00.8-0.80.90.9-0.9-0.9
Reaction time trials correct on left0.81.11.3-1.11.1-1.20.91.0-1.0-1.0
Reaction time trials on left0.81.11.4-1.21.1-1.21.01.0-1.0-1.0
Reaction time mean0.91.21.40.9-1.21.1-0.8-1.21.21.2
Reaction time mean AUC0.70.91.20.8-1.00.9-0.7-1.11.11.0
Median of all reaction times1.01.41.61.0-1.31.3-0.9-1.21.21.2
Reaction time omissions0.10.10.3-0.2-0.10.20.50.3-0.3-0.3
Reaction time false alarm rate0.00.00.1-0.20.1-0.00.20.2-0.2-0.2
Reaction time premature initiation rate0.10.20.30.5-0.50.5-0.5-0.40.40.4
Reaction time premature initiations0.00.00.1-0.20.2-0.20.10.2-0.2-0.2
Std. dev. reaction times0.20.30.50.5-0.50.5-0.4-0.70.70.7
Reaction time trials completed0.81.11.4-1.21.1-1.21.01.0-1.0-1.0
Reaction time trials AUC1.01.51.8-1.31.3-1.31.11.2-1.2-1.1
Social response proportion0.30.30.60.6-0.50.4-0.3-0.80.70.7
Social responses0.10.10.2-0.10.1-0.10.1-0.40.40.3
Social time0.60.81.40.7-0.60.5-0.7-1.21.21.1
Conditioned locomotion3.44.04.7-1.92.2-2.21.72.0-2.0-2.0
Cocaine response after cond. corrected1.82.02.6-1.41.3-1.31.61.4-1.5-1.5
Cocaine response after cond. not corrected3.33.73.9-1.91.9-1.92.01.9-1.9-1.9
Cocaine response before conditioning1.01.21.8-1.11.3-1.40.91.0-1.0-1.0
Saline control response0.60.81.5-1.00.7-0.71.20.9-0.9-0.9
Condit. Reinf. active minus inactive responses3.84.75.1-2.12.2-2.22.02.3-2.3-2.2
Condit. Reinf. active-inactive response ratio0.90.91.1-0.91.0-1.00.61.1-1.0-1.0
Condit. Reinf. active responses3.14.34.5-2.02.1-2.11.82.1-2.1-2.1
Condit. Reinf. inactive responses2.02.52.7-1.61.6-1.61.51.6-1.6-1.6
Condit. Reinf. lever presses2.02.83.2-1.61.8-1.81.41.7-1.7-1.7
Condit. Reinf. lever reinforcers received2.63.74.1-1.92.0-2.01.72.0-1.9-1.9
Pavlov. Cond. lever latency1.62.22.31.5-1.51.4-1.4-1.51.51.5
Pavlov. Cond. magazine entry latency0.10.10.2-0.40.2-0.20.50.4-0.4-0.4
Pavlov. Cond. change in total contacts0.71.01.5-1.01.2-1.20.71.0-0.9-0.9
Pavlov. Cond. index score0.81.01.1-1.01.0-1.00.91.0-1.0-1.0
Pavlov. Cond. latency score0.60.80.9-0.90.9-0.80.81.0-1.0-0.9
Pavlov. Cond. lever contacts0.91.21.4-1.01.2-1.20.91.1-1.1-1.1
Pavlov. Cond. magazine entry number0.10.10.10.4-0.30.3-0.3-0.20.20.2
Pavlov. Cond. intertrial magazine entries2.73.43.61.9-1.81.8-1.8-1.91.91.9
Pavlov. Cond. lever-magazine prob. diff.0.50.60.7-0.80.8-0.80.60.8-0.8-0.8
Pavlov. Cond. response bias1.72.32.5-1.51.6-1.61.41.5-1.5-1.5
Conditioned reinforcement - actives0.20.20.3-0.50.5-0.50.40.4-0.4-0.4
Conditioned reinforcement - inactives1.71.92.2-1.41.3-1.31.51.4-1.4-1.4
Conditioned locomotion0.10.10.30.20.0-0.1-0.5-0.40.40.4
Intermittent access intake day 1-15 change0.10.10.2-0.20.4-0.5-0.3-0.00.00.0
Intermittent access intake escalation0.10.10.30.10.2-0.3-0.5-0.30.30.3
Intermittent access intake escalation 20.50.51.10.6-0.20.1-1.0-0.80.80.8
Intermitt. access day 1 inactive lever presses0.00.00.10.3-0.30.3-0.0-0.10.10.1
Intermitt. access day 15 inactive lever presses4.65.06.1-2.32.4-2.52.22.1-2.1-2.1
Intermitt. access escalation Index1.10.92.00.9-1.31.4-0.4-0.80.80.8
Intermittent access day 1 total infusions3.94.46.1-1.81.9-1.92.52.2-2.2-2.2
Intermittent access day 15 total infusions1.51.61.9-1.21.4-1.41.31.2-1.2-1.2
Intermittent access terminal intake (last 3 days)1.11.21.4-1.01.2-1.21.21.1-1.1-1.1
Intermittent access total infusions1.51.61.8-1.11.3-1.31.31.3-1.3-1.3
Intermittent access day 1 locomotion2.52.53.0-1.41.7-1.71.71.5-1.5-1.6
Intermittent access day 15 total locomotion0.50.50.9-0.50.9-0.90.50.6-0.6-0.6
Intermittent access total locomotion0.20.30.7-0.30.8-0.80.40.4-0.4-0.4
Intermittent access standard deviation0.10.10.3-0.10.5-0.6-0.2-0.00.00.0
Cocaine induced anxiety0.00.00.1-0.2-0.10.20.30.2-0.2-0.2
Post-drug Anxiety0.80.91.20.7-1.01.1-1.0-0.90.90.9
Baseline Anxiety0.40.50.70.5-0.60.6-0.9-0.70.70.7
Lifetime Intake1.71.92.2-1.21.4-1.41.51.4-1.4-1.4
Incentive Sensitization - Responses0.30.30.60.4-0.70.8-0.4-0.30.30.3
Incentive Sensitization - Breakpoint0.40.40.80.6-0.90.9-0.6-0.50.50.5
Progressive ratio test 1 active lever presses0.30.30.5-0.40.4-0.40.70.6-0.6-0.6
Progressive ratio test 1 breakpoint0.20.20.4-0.30.4-0.40.60.5-0.5-0.5
Progressive ratio test 1 inactive lever presses1.01.11.5-0.81.2-1.21.21.0-1.0-1.0
Progressive ratio test 2 active lever presses0.10.10.30.3-0.50.5-0.2-0.10.10.1
Progressive ratio test 2 breakpoint0.10.10.20.3-0.40.4-0.1-0.10.10.1
Progressive ratio test 2 inactive lever presses0.50.60.8-0.70.7-0.70.90.8-0.8-0.8
Total sessions with >9 infusions0.60.71.2-0.60.7-0.71.10.8-0.8-0.8
Short access day 1 total inactive lever presses2.62.94.4-1.61.5-1.42.11.8-1.8-1.8
Short access day 10 total inactive lever presses0.50.50.7-0.70.8-0.80.70.7-0.7-0.7
Short access day 1 total infusions1.41.52.7-1.01.0-1.01.61.3-1.3-1.3
Short access day 10 total infusions2.62.93.4-1.51.6-1.51.81.8-1.8-1.8
Short access total infusions1.11.21.6-0.81.1-1.11.31.1-1.1-1.1
Short access day 1 locomotion4.44.75.4-2.12.2-2.22.32.1-2.1-2.1
Short access day 10 total locomotion1.21.32.3-1.11.4-1.51.10.9-0.9-1.0
Short access total locomotion0.30.30.6-0.40.7-0.80.60.4-0.4-0.4
Compulsive drug intake0.20.20.60.8-0.50.6-0.5-0.30.30.3
One hour access (0.3 mA shock)0.91.11.4-0.80.9-0.81.11.2-1.2-1.2
One hour access (shock baseline)1.11.21.3-1.11.1-1.11.21.1-1.1-1.1
Number of responses in last shaping day0.10.10.2-0.30.4-0.50.20.2-0.2-0.2
Context. condit. distance diff. score0.00.10.20.3-0.10.1-0.4-0.20.20.2
Locomotion velocity, session 10.10.10.10.2-0.30.3-0.2-0.40.40.3
Locomotion distance, session 11.92.43.2-1.51.4-1.31.81.6-1.6-1.6
Locomotion velocity, session 20.10.10.20.3-0.30.3-0.5-0.40.40.4
Locomotion distance, session 20.00.00.0-0.0-0.10.10.1-0.10.00.0
Locomotion velocity, session 30.20.30.4-0.50.2-0.20.50.6-0.6-0.6
Locomotion distance, session 30.90.91.2-1.00.9-0.81.11.0-1.0-1.0
Stereotopy head waving bouts, day 31.11.31.6-1.11.1-1.10.91.2-1.2-1.2
Stereotopy head waving duration, day 30.00.00.00.0-0.10.1-0.10.2-0.2-0.1
Locomotion velocity, session 70.80.91.6-1.01.2-1.20.70.8-0.8-0.8
Locomotion distance, session 70.00.00.10.2-0.00.0-0.4-0.10.20.2
Stereotopy head waving bouts, day 70.00.00.1-0.20.2-0.30.2-0.00.0-0.0
Stereotopy head waving duration, day 70.50.71.0-0.80.8-0.91.00.7-0.7-0.7
Locomotion velocity, session 80.10.10.50.3-0.60.7-0.1-0.00.00.1
Locomotion distance, session 80.30.40.7-0.60.8-0.90.40.5-0.5-0.5
Degree of sensitization distance1.11.11.71.1-0.90.8-1.3-1.11.11.1
Degree of sensitization stereotypy0.00.00.0-0.00.1-0.10.2-0.20.20.1
Condit. Reinf. active minus inactive responses0.30.30.50.3-0.40.3-0.7-0.60.60.6
Condit. Reinf. active-inactive response ratio0.30.30.40.3-0.40.4-0.6-0.60.60.6
Condit. Reinf. active responses0.50.70.9-0.90.9-0.90.80.7-0.7-0.7
Condit. Reinf. inactive responses1.72.02.5-1.31.3-1.21.61.5-1.5-1.5
Incentive salience index mean0.20.30.6-0.70.7-0.80.30.3-0.3-0.3
Condit. Reinf. lever presses1.41.92.7-1.51.6-1.61.31.2-1.2-1.2
Time in familiar zone, hab. session 10.90.91.10.9-1.01.0-0.8-0.90.90.9
Time in novel zone, hab. session 10.80.70.90.9-0.90.9-0.7-0.80.80.8
Total zone transitions, hab. session 10.10.20.2-0.40.4-0.40.40.4-0.4-0.4
Total locomotion distance, hab. session 10.00.10.1-0.30.2-0.20.20.3-0.3-0.3
Locomotion velocity, hab. session 11.01.41.5-1.21.2-1.21.11.2-1.2-1.2
Time in familiar zone, hab. session 20.00.00.0-0.10.1-0.1-0.0-0.10.10.1
Time in novel zone, hab. session 20.50.50.80.8-0.90.9-0.6-0.60.60.6
Total zone transitions, hab. session 20.20.30.3-0.50.5-0.50.50.5-0.5-0.5
Total locomotion distance, hab. session 20.20.30.4-0.60.6-0.60.30.5-0.5-0.5
Locomotion velocity, hab. session 20.40.60.7-0.80.8-0.80.60.8-0.8-0.8
Novel to familiar place preference ratio0.40.40.50.6-0.50.5-0.6-0.70.70.7
Novelty place preference0.80.81.00.8-0.70.7-0.9-1.01.01.0
Time in novel zone, NPP test1.01.11.31.0-0.90.9-1.1-1.21.21.1
Total zone transitions, NPP test1.62.32.3-1.51.5-1.51.51.5-1.5-1.5
Total locomotion distance, NPP test1.82.52.6-1.61.6-1.61.51.6-1.6-1.6
Locomotion velocity, NPP test3.44.95.0-2.22.2-2.22.12.2-2.2-2.2
Pavlov. Cond. lever latency2.02.63.81.7-1.92.0-1.2-1.51.51.4
Pavlov. Cond. magazine entry latency0.00.00.1-0.30.3-0.4-0.00.1-0.1-0.1
Pavlov. Cond. change in total contacts0.20.20.6-0.50.7-0.8-0.00.2-0.2-0.2
Pavlov. Cond. index score1.01.32.3-1.21.4-1.50.70.9-0.9-0.9
Pavlov. Cond. latency score0.91.12.1-1.11.4-1.40.60.9-0.9-0.9
Pavlov. Cond. lever contacts1.51.72.7-1.41.6-1.60.91.2-1.2-1.2
Pavlov. Cond. magazine entry number0.40.50.80.8-0.90.9-0.4-0.60.60.6
Pavlov. Cond. intertrial magazine entries1.31.62.0-1.21.1-1.01.41.3-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.2.12.74.2-1.72.0-2.11.21.4-1.4-1.4
Pavlov. Cond. response bias1.72.13.1-1.51.7-1.81.11.3-1.3-1.3
Bone: apparent density4.98.09.6-2.82.5-2.43.13.0-3.0-3.0
Bone surface2.34.04.5-1.92.1-2.11.92.0-2.0-2.0
Bone volume2.54.24.4-1.92.0-2.02.12.1-2.1-2.1
Bone: connectivity density4.87.58.8-2.72.4-2.43.02.9-2.9-2.9
Bone: cortical apparent density0.40.50.7-0.80.6-0.60.70.8-0.8-0.8
Bone: cortical area0.60.91.6-1.01.2-1.30.90.7-0.7-0.8
Bone: cortical porosity1.21.31.3-1.11.2-1.21.21.1-1.1-1.1
Bone: cortical porosity1.01.01.2-1.01.0-1.01.11.0-1.0-1.0
Bone: cortical thickness0.00.00.1-0.20.3-0.30.2-0.10.00.0
Bone: cortical thickness2.02.43.4-1.51.8-1.81.41.4-1.4-1.4
Bone: cortical tissue density0.30.40.5-0.60.5-0.50.50.7-0.7-0.7
Bone: elastic displacement1.11.21.3-1.11.1-1.11.21.1-1.1-1.1
Bone: elastic work1.51.92.3-1.41.5-1.51.31.3-1.3-1.3
Bone: endosteal estimation0.30.71.3-0.61.1-1.10.40.8-0.8-0.7
Bone: endosteal perimeter0.10.30.6-0.40.7-0.70.20.5-0.5-0.4
Bone: final force0.20.30.6-0.60.8-0.80.40.4-0.4-0.4
Bone: final moment0.20.30.6-0.60.7-0.80.40.4-0.4-0.4
Bone: marrow area0.40.81.4-0.71.1-1.20.50.8-0.8-0.8
Bone: maximum diameter1.22.13.0-1.41.7-1.71.31.3-1.3-1.3
Bone: maximum force0.00.10.2-0.30.4-0.50.20.1-0.1-0.1
Bone: maximum moment0.10.10.3-0.30.5-0.50.20.2-0.2-0.2
Bone: minimum diameter0.10.10.20.30.0-0.1-0.3-0.40.40.4
Bone: periosteal estimation0.71.52.6-1.11.6-1.60.91.1-1.1-1.1
Bone: periosteal perimeter0.30.51.0-0.61.0-1.00.50.6-0.6-0.6
Bone: post-yield work0.40.50.5-0.70.7-0.70.70.7-0.7-0.7
Bone: stiffness0.00.10.10.00.3-0.3-0.3-0.20.20.2
Bone: tissue strength0.70.61.30.8-1.11.1-0.5-0.70.70.7
Bone: trabecular number4.06.27.6-2.52.2-2.12.82.6-2.6-2.6
Bone: trabecular spacing1.92.43.11.5-1.31.3-1.5-1.81.71.7
Bone: trabecular thickness0.40.50.8-0.70.5-0.50.90.8-0.8-0.8
Bone: trabecular tissue density0.10.10.2-0.30.4-0.40.00.3-0.3-0.3
Breakpoint value in progressive ratio session0.60.71.0-0.60.7-0.61.00.9-0.9-0.9
Distance traveled before self-admin0.10.10.1-0.30.3-0.20.10.3-0.3-0.3
Distance traveled after self-admin0.40.50.70.5-0.80.8-0.7-0.70.70.7
Delta time in closed arm before/after self-admin0.10.10.10.2-0.30.3-0.2-0.20.20.2
Delta time in open arm before/after self-admin0.50.50.9-0.70.4-0.41.00.7-0.7-0.7
Diff in mean of infusions in LGA sessions0.10.10.3-0.10.2-0.20.50.3-0.3-0.3
Extinction: sum of active levers before priming1.01.01.4-0.81.2-1.20.90.9-0.9-1.0
Active lever presses in extinction session 60.10.10.20.3-0.30.40.10.0-0.0-0.0
Delta distance traveled before/after self-admin1.92.02.11.4-1.41.4-1.2-1.41.41.4
Delta ambulatory time before/after self-admin0.40.50.60.8-0.70.8-0.5-0.70.70.7
Time in closed arm before self-admin0.40.50.70.6-0.60.5-0.6-0.80.80.8
Time in closed arm after self-admin1.51.51.61.2-1.21.2-1.2-1.31.31.3
Time in open arm before self-admin0.10.10.2-0.40.3-0.30.10.5-0.5-0.4
Time in open arm after self-admin2.42.63.1-1.61.3-1.31.81.7-1.7-1.8
Sum of active levers in priming session hrs 5-61.31.31.6-1.11.3-1.31.01.1-1.1-1.1
Time to tail flick, vehicle, before self-admin1.91.92.11.1-1.41.4-1.4-1.51.41.4
Time to tail flick, vehicle, after self-admin3.23.44.01.7-1.81.8-1.6-2.02.02.0
Time to tail flick, test, before self-admin0.40.40.7-0.60.4-0.30.80.7-0.7-0.7
Time to tail flick, test, after self-admin0.10.10.10.1-0.30.3-0.4-0.20.20.3
Delta time to tail flick, vehicle, before/after SA0.00.00.00.10.0-0.0-0.0-0.20.20.2
Delta time to tail flick, test, before/after SA0.50.40.6-0.70.8-0.80.30.6-0.6-0.6
Ambulatory time before self-admin0.30.30.4-0.70.6-0.60.30.6-0.6-0.6
Ambulatory time after self-admin0.30.30.40.4-0.60.6-0.5-0.50.50.5
Total heroin consumption2.63.13.7-1.71.7-1.61.91.8-1.8-1.8
Area under the delay curve1.21.21.3-1.11.1-1.11.11.1-1.1-1.1
Delay disc. indifference point, 0s delay0.40.50.60.7-0.70.6-0.6-0.80.70.7
Delay disc. indifference point, 16s delay1.21.21.6-1.00.8-0.81.31.2-1.2-1.2
Delay disc. indifference point, 2s delay0.00.00.00.1-0.10.1-0.1-0.20.20.2
Delay disc. indifference point, 24s delay5.45.35.6-2.32.2-2.22.32.3-2.4-2.4
Delay disc. indifference point, 4s delay0.10.10.2-0.30.1-0.10.40.4-0.4-0.4
Delay disc. indifference point, 8s delay1.21.31.7-1.11.2-1.31.01.1-1.1-1.1
Delay discount exponential model param1.81.92.11.4-1.41.4-1.3-1.41.41.4
Delay discount hyperbolic model param1.61.71.81.3-1.31.3-1.3-1.31.31.3
Fecal boli incidents, locomotor time 10.60.60.8-0.80.9-0.90.60.8-0.8-0.8
Change in fecal boli incidents, locomotor task4.84.55.92.1-2.42.4-1.8-2.02.02.0
Time >=10cm from walls, locomotor time 10.10.10.2-0.40.3-0.30.40.3-0.3-0.3
Bouts of movement, locomotor time 14.55.05.9-2.22.4-2.42.12.2-2.2-2.2
Total resting periods, locomotor time 14.55.06.3-2.22.4-2.52.02.2-2.2-2.2
Rest time, locomotor task time 10.10.10.3-0.20.5-0.5-0.20.1-0.1-0.1
Distance moved, locomotor task time 11.01.11.91.0-1.31.4-0.6-1.01.01.0
Vertical activity count, locomotor time 10.30.30.50.7-0.60.6-0.4-0.50.50.5
Time >=10cm from walls, locomotor time 20.00.00.0-0.0-0.10.10.10.1-0.1-0.1
Bouts of movement, locomotor time 20.10.10.20.10.3-0.4-0.5-0.10.10.2
Total resting periods, locomotor time 20.10.10.3-0.10.5-0.5-0.30.1-0.0-0.0
Rest time, locomotor task time 21.92.23.0-1.61.7-1.71.01.4-1.4-1.4
Distance moved, locomotor task time 21.31.52.11.3-1.41.4-0.8-1.21.21.2
Vertical activity count, locomotor time 20.91.01.31.2-1.00.9-0.9-1.01.01.0
Weight adjusted by age0.10.10.20.2-0.40.4-0.3-0.40.40.4
Seeking ratio, delayed vs. immediate footshock0.40.40.70.8-0.70.7-0.5-0.60.60.6
Locomotion in novel chamber1.21.51.71.1-1.31.3-1.2-1.21.21.2
Locomotion in novel chamber post-restriction1.92.32.51.6-1.61.6-1.4-1.51.51.5
Progressive ratio0.60.70.90.9-0.70.8-0.9-0.80.80.8
Food seeking constrained by brief footshock2.73.34.1-2.01.9-1.91.81.7-1.7-1.7
Seeking ratio, punishment vs. effort1.92.42.9-1.71.6-1.61.51.4-1.4-1.5
Run reversals in cocaine runway, females0.00.00.0-0.10.2-0.2-0.20.1-0.1-0.1
Run reversals in cocaine runway, males1.01.01.8-0.91.3-1.30.90.8-0.8-0.8
Latency to leave start box in cocaine runway0.20.20.4-0.40.00.10.70.6-0.6-0.6
Latency to leave start box in cocaine runway, F0.30.30.6-0.40.10.00.80.7-0.7-0.7
Latency to leave start box in cocaine runway, M0.10.10.1-0.30.3-0.30.20.3-0.3-0.3
Cd content in liver0.10.10.1-0.30.3-0.30.30.2-0.2-0.2
Co content in liver7.38.69.7-3.02.9-2.93.12.9-2.9-2.9
Cu content in liver0.10.10.2-0.40.2-0.20.50.3-0.3-0.3
Fe content in liver0.10.10.10.2-0.10.1-0.4-0.30.30.3
K content in liver0.30.30.60.6-0.40.4-0.8-0.40.40.4
Mg content in liver0.30.40.50.7-0.60.6-0.7-0.50.50.5
Mn content in liver0.30.30.4-0.50.6-0.60.50.6-0.6-0.6
Na content in liver0.20.30.5-0.40.7-0.70.20.5-0.5-0.4
Rb content in liver0.00.00.10.3-0.30.3-0.2-0.10.10.1
Se content in liver0.60.70.80.8-0.90.9-0.8-0.90.90.9
Sr content in liver0.10.10.20.3-0.30.3-0.4-0.20.20.2
Zn content in liver0.80.91.20.7-1.11.1-0.3-1.01.00.9