Hub : Genes

Zmiz2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000025923 0.19 0.09 3.8e-13 0.13 0.11 0.12 0.13 4.7e-12 9.9e-11 1.2e-11 6.9e-12
2 Brain isoform ratio ENSRNOT00000077428 0.04 0.03 4.0e-03 0.02 0.01 0 0.01 5.8e-03 3.5e-02 1.2e-01 4.8e-02
3 Brain intron excision ratio chr14:81251849:81257362 0.21 0.1 2.0e-09 0.12 0.11 0.11 0.11 5.8e-11 2.4e-10 4.8e-10 1.8e-10
4 Brain intron excision ratio chr14:81258125:81258465 0.09 0.06 3.1e-04 0.02 0.04 0.04 0.04 2.3e-03 1.5e-04 6.8e-05 1.4e-04
5 Liver gene expression ENSRNOG00000025923 0.09 0.05 6.5e-09 0.06 0.08 0.08 0.08 1.1e-07 4.5e-09 4.2e-09 5.6e-09
6 Liver intron excision ratio chr14:81259892:81260495 0.06 0.05 1.7e-05 0.05 0.04 0.03 0.04 7.4e-06 3.2e-05 3.8e-04 1.8e-05
7 Liver intron excision ratio chr14:81260572:81260790 0.05 0.04 4.5e-05 0.04 0.03 0.04 0.04 7.0e-05 1.0e-04 6.4e-05 3.9e-05
8 PL gene expression ENSRNOG00000025923 0.08 0.05 1.2e-03 0.04 0.04 0.03 0.04 3.4e-04 4.2e-04 2.6e-03 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.00.10.3-0.20.4-0.40.4-0.60.1-0.1-0.2
BMI without tail0.00.10.2-0.10.3-0.50.20.0-0.30.3-0.1
Body weight1.25.17.7-2.32.80.50.8-2.82.6-2.6-2.3
Epididymis fat weight0.30.60.91.0-0.9-0.2-0.50.5-0.91.01.0
Glucose11.317.334.8-5.04.2-4.25.9-3.41.7-1.7-5.0
Heart weight0.40.61.20.3-0.6-1.10.80.3-1.01.00.3
Left kidney weight0.30.93.70.4-0.21.9-1.5-0.20.5-0.50.4
Right kidney weight0.82.25.41.6-1.51.8-2.30.8-0.70.71.6
Tail length1.03.14.7-2.02.20.60.5-1.72.1-2.1-2.0
Length with tail1.76.210.1-2.52.81.30.4-2.73.2-3.2-2.5
Length without tail0.92.03.4-1.31.50.80.3-1.71.8-1.8-1.3
Liver weight, left1.93.14.22.0-2.00.9-2.12.0-1.41.42.0
Liver weight, right4.06.613.73.0-2.52.4-3.72.5-1.11.13.0
Parametrial fat weight1.12.23.3-1.81.7-0.51.1-1.61.5-1.5-1.8
Retroperitoneal fat weight0.10.20.8-0.00.20.9-0.6-0.40.5-0.5-0.0
Intraocular pressure0.30.50.7-0.70.8-0.10.7-0.80.7-0.7-0.7
Extensor digitorum longus weight2.18.613.0-3.63.5-1.02.3-3.32.6-2.6-3.6
Soleus weight0.61.72.7-1.01.60.9-0.4-1.51.6-1.6-1.0
Tibialis anterior weight0.93.14.7-2.12.0-0.81.7-2.21.4-1.4-2.1
Tibia length0.30.82.60.6-0.21.6-1.4-0.10.7-0.70.6
Number of licking bursts2.73.25.1-1.81.90.50.9-2.32.1-2.1-1.8
Food consumed during 24 hour testing period1.61.93.7-1.71.4-1.11.9-1.10.8-0.8-1.7
Times rat made contact with spout2.22.67.5-0.2-0.5-2.72.50.6-1.71.7-0.2
Mean time between licks in bursts0.30.41.1-0.70.5-0.71.1-0.40.2-0.2-0.7
Mean num. licks in bursts3.44.17.91.4-1.9-2.10.72.2-2.82.81.4
Std. dev. time between licks in bursts0.10.10.3-0.20.20.30.1-0.20.5-0.5-0.2
Water consumed over 24 hours1.11.33.7-1.31.1-1.11.9-0.90.5-0.5-1.3
Indifference point 0 sec2.43.97.9-2.02.0-1.72.8-2.31.2-1.2-2.0
Indifference point AUC0.20.20.8-0.40.4-0.60.9-0.10.2-0.2-0.4
Indifference point function ln k0.10.20.70.10.10.8-0.7-0.20.4-0.40.1
Indifference point function log k0.10.20.70.10.10.8-0.7-0.20.4-0.40.1
Delay discounting total patch changes 0 sec2.74.39.0-2.12.1-1.83.0-2.41.2-1.2-2.1
Delay discounting total patch changes 12 sec1.82.46.3-1.41.5-1.92.5-1.50.7-0.7-1.4
Delay discounting total patch changes 18 sec2.63.57.9-1.81.9-1.82.8-1.91.2-1.2-1.8
Delay discounting total patch changes 24 sec0.81.03.30.5-0.4-1.81.60.4-0.90.90.5
Delay discounting total patch changes 6 sec2.63.98.2-2.12.0-1.92.9-2.11.0-1.0-2.1
Delay discounting time to switch 0 sec0.40.61.10.9-0.90.5-1.00.7-0.60.60.9
Delay discounting water rate 0 sec1.93.04.9-2.02.0-1.52.2-1.61.1-1.1-2.0
Delay discounting water rate 12 sec0.20.20.3-0.50.6-0.10.3-0.40.6-0.6-0.5
Delay discounting water rate 18 sec0.50.72.90.2-0.01.5-1.7-0.10.5-0.50.2
Delay discounting water rate 24 sec0.10.10.2-0.20.4-0.40.10.3-0.10.1-0.2
Delay discounting water rate 6 sec0.50.81.7-0.50.91.0-0.4-0.41.3-1.3-0.5
Locomotor activity0.61.02.9-1.00.8-1.31.7-0.70.2-0.2-1.0
Locomotor testing distance0.30.51.0-0.50.60.50.1-0.81.0-1.0-0.5
Locomotor testing rearing1.62.63.8-1.71.9-0.91.9-1.71.3-1.3-1.7
Light reinforcement 10.20.40.9-0.40.70.7-0.1-0.60.9-0.9-0.4
Light reinforcement 21.11.55.60.10.12.4-1.8-0.41.2-1.20.1
Reaction time number correct0.10.20.8-0.30.3-0.70.9-0.1-0.10.2-0.3
Reaction time mean minus median1.62.13.71.4-1.6-0.90.21.4-1.91.91.4
Reaction time mean minus median AUC1.11.42.21.3-1.5-0.50.21.2-1.41.41.3
Reaction time num false alarms0.81.01.7-0.91.10.40.2-1.31.3-1.3-0.9
Reaction time num false alarms AUC0.81.12.1-0.81.00.8-0.2-1.41.3-1.3-0.8
Reaction time trials correct on left0.10.20.8-0.30.3-0.70.9-0.1-0.10.2-0.3
Reaction time trials on left0.10.20.7-0.30.3-0.70.9-0.1-0.20.2-0.3
Reaction time mean0.71.01.90.9-1.2-0.3-0.60.9-1.41.40.9
Reaction time mean AUC1.21.52.41.3-1.5-0.1-1.01.1-1.51.51.3
Median of all reaction times0.50.61.10.6-0.9-0.1-0.90.6-1.11.10.6
Reaction time omissions0.60.81.31.0-1.1-0.4-0.30.7-1.11.11.0
Reaction time false alarm rate0.71.01.8-0.60.81.1-0.6-1.31.3-1.3-0.6
Reaction time premature initiation rate2.02.74.02.0-1.80.8-1.72.0-1.11.12.0
Reaction time premature initiations0.91.32.31.4-1.20.2-0.91.5-1.01.01.4
Std. dev. reaction times1.21.63.01.2-1.5-0.7-0.11.1-1.71.71.2
Reaction time trials completed0.10.20.7-0.30.3-0.70.9-0.1-0.20.2-0.3
Reaction time trials AUC0.10.20.7-0.40.3-0.60.8-0.2-0.10.1-0.4
Social response proportion0.91.01.6-1.21.3-0.10.5-0.91.1-1.1-1.2
Social responses2.12.74.6-1.92.1-1.11.7-1.51.3-1.3-1.9
Social time0.40.61.2-0.81.0-1.10.9-0.50.2-0.2-0.8
Conditioned locomotion0.91.13.61.0-0.61.4-1.90.50.4-0.41.0
Cocaine response after cond. corrected1.11.32.0-1.11.10.60.3-1.41.4-1.4-1.1
Cocaine response after cond. not corrected1.21.32.3-1.11.10.60.2-1.51.5-1.5-1.1
Cocaine response before conditioning0.30.30.60.8-0.50.3-0.60.5-0.40.40.8
Saline control response0.20.30.50.5-0.5-0.70.30.6-0.70.70.5
Condit. Reinf. active minus inactive responses0.20.20.40.6-0.50.3-0.30.6-0.30.30.6
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.30.6-0.2-0.30.5-0.5-0.1
Condit. Reinf. active responses0.40.61.10.9-0.80.0-0.51.0-0.70.80.9
Condit. Reinf. inactive responses1.01.32.11.1-1.3-0.6-0.21.5-1.31.31.1
Condit. Reinf. lever presses0.20.30.50.7-0.60.5-0.40.6-0.10.10.7
Condit. Reinf. lever reinforcers received0.30.40.80.8-0.70.3-0.50.9-0.50.50.8
Pavlov. Cond. lever latency2.53.45.1-1.92.30.80.0-2.22.2-2.2-1.9
Pavlov. Cond. magazine entry latency0.10.10.40.1-0.20.6-0.10.00.3-0.30.1
Pavlov. Cond. change in total contacts0.20.30.60.6-0.70.1-0.20.7-0.40.40.6
Pavlov. Cond. index score0.81.12.01.2-1.40.2-0.31.3-1.01.01.2
Pavlov. Cond. latency score0.81.01.81.2-1.30.4-0.51.2-0.80.81.2
Pavlov. Cond. lever contacts2.12.94.61.9-2.1-0.3-0.22.1-1.81.81.9
Pavlov. Cond. magazine entry number0.20.30.80.00.30.7-0.9-0.30.6-0.60.0
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.3-0.10.0-0.10.1-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.12.01.2-1.40.2-0.31.3-1.01.01.2
Pavlov. Cond. response bias0.91.32.31.2-1.5-0.30.21.5-1.21.31.2
Conditioned reinforcement - actives0.00.00.10.00.0-0.1-0.10.30.0-0.00.0
Conditioned reinforcement - inactives0.00.00.1-0.20.10.2-0.0-0.20.3-0.3-0.2
Conditioned locomotion0.10.10.2-0.10.4-0.4-0.10.10.4-0.4-0.1
Intermittent access intake day 1-15 change0.80.83.2-0.70.5-1.21.8-0.50.3-0.3-0.7
Intermittent access intake escalation0.60.62.6-0.50.3-1.21.6-0.30.1-0.1-0.5
Intermittent access intake escalation 20.60.63.0-0.40.4-1.11.7-0.1-0.00.0-0.4
Intermitt. access day 1 inactive lever presses0.91.03.20.8-0.61.5-1.80.7-0.20.20.8
Intermitt. access day 15 inactive lever presses1.31.41.6-1.31.2-0.81.2-1.01.2-1.2-1.3
Intermitt. access escalation Index0.70.62.5-0.60.4-1.11.6-0.30.2-0.2-0.6
Intermittent access day 1 total infusions0.50.51.60.6-0.61.3-1.10.4-0.10.10.6
Intermittent access day 15 total infusions0.10.10.4-0.30.2-0.40.6-0.40.3-0.3-0.3
Intermittent access terminal intake (last 3 days)0.20.31.3-0.20.1-0.81.1-0.20.1-0.1-0.2
Intermittent access total infusions0.00.00.0-0.1-0.0-0.00.2-0.10.2-0.2-0.1
Intermittent access day 1 locomotion1.31.33.71.1-1.00.7-1.91.4-0.80.81.1
Intermittent access day 15 total locomotion0.10.10.3-0.30.4-0.5-0.4-0.20.3-0.3-0.3
Intermittent access total locomotion0.20.20.5-0.40.50.4-0.7-0.20.6-0.6-0.4
Intermittent access standard deviation1.61.73.01.0-1.2-1.20.61.7-1.61.61.0
Cocaine induced anxiety2.32.64.0-2.02.0-1.01.3-1.41.5-1.5-2.0
Post-drug Anxiety0.70.81.4-1.11.20.30.7-0.70.8-0.8-1.1
Baseline Anxiety0.40.41.10.6-0.71.1-0.70.1-0.40.40.6
Lifetime Intake0.00.00.1-0.10.0-0.10.1-0.10.2-0.2-0.1
Incentive Sensitization - Responses0.10.10.40.0-0.0-0.60.5-0.4-0.00.00.0
Incentive Sensitization - Breakpoint0.10.10.50.1-0.1-0.70.6-0.4-0.10.10.1
Progressive ratio test 1 active lever presses0.20.20.90.0-0.21.0-0.30.20.3-0.30.0
Progressive ratio test 1 breakpoint0.30.31.50.4-0.61.2-0.70.50.0-0.00.4
Progressive ratio test 1 inactive lever presses2.12.23.7-1.51.60.9-0.6-1.31.9-1.9-1.5
Progressive ratio test 2 active lever presses0.00.00.30.0-0.10.50.1-0.20.2-0.10.0
Progressive ratio test 2 breakpoint0.00.00.1-0.1-0.00.30.3-0.20.2-0.2-0.1
Progressive ratio test 2 inactive lever presses0.40.50.9-0.70.80.1-0.0-0.71.0-0.9-0.7
Total sessions with >9 infusions0.00.00.10.2-0.2-0.10.10.3-0.10.10.2
Short access day 1 total inactive lever presses2.22.53.8-1.82.00.60.3-1.51.8-1.8-1.8
Short access day 10 total inactive lever presses0.20.20.60.3-0.10.7-0.80.4-0.10.10.3
Short access day 1 total infusions0.50.51.20.7-0.50.4-1.10.9-0.40.40.7
Short access day 10 total infusions0.40.40.80.7-0.90.8-0.80.5-0.20.20.7
Short access total infusions0.30.40.60.7-0.70.0-0.50.8-0.50.50.7
Short access day 1 locomotion1.51.63.41.4-1.21.1-1.81.2-0.90.91.4
Short access day 10 total locomotion1.61.76.10.9-0.81.4-2.51.6-0.70.70.9
Short access total locomotion3.53.65.72.0-1.91.3-2.22.4-1.61.62.0
Compulsive drug intake1.41.42.21.5-1.40.9-0.91.1-1.11.11.5
One hour access (0.3 mA shock)0.10.10.50.2-0.00.7-0.50.3-0.10.10.2
One hour access (shock baseline)0.20.20.5-0.70.6-0.1-0.0-0.20.4-0.4-0.7
Number of responses in last shaping day0.20.20.70.10.10.8-0.5-0.20.4-0.40.1
Context. condit. distance diff. score2.02.43.51.8-1.9-0.1-0.61.7-1.81.81.8
Locomotion velocity, session 10.20.20.50.2-0.5-0.40.20.7-0.60.50.2
Locomotion distance, session 11.11.44.21.0-0.82.0-2.00.70.3-0.31.0
Locomotion velocity, session 20.50.51.5-0.2-0.3-1.01.20.6-0.80.8-0.2
Locomotion distance, session 20.71.01.81.1-1.10.7-0.91.4-0.80.81.1
Locomotion velocity, session 31.31.52.11.5-1.40.9-1.21.4-1.01.01.5
Locomotion distance, session 30.40.40.7-0.80.9-0.00.5-0.70.5-0.5-0.8
Stereotopy head waving bouts, day 30.40.51.20.8-0.80.2-0.71.1-0.60.60.8
Stereotopy head waving duration, day 31.62.03.41.6-1.70.1-1.01.8-1.41.41.6
Locomotion velocity, session 70.20.20.4-0.60.5-0.30.5-0.30.3-0.3-0.6
Locomotion distance, session 70.10.10.10.2-0.3-0.20.30.3-0.30.30.2
Stereotopy head waving bouts, day 70.60.71.11.0-1.10.4-0.60.8-0.80.81.0
Stereotopy head waving duration, day 70.20.20.80.4-0.40.8-0.90.2-0.00.00.4
Locomotion velocity, session 80.70.81.40.9-1.20.10.21.1-1.01.00.9
Locomotion distance, session 84.66.910.23.0-3.10.2-1.43.2-2.82.83.0
Degree of sensitization distance1.91.93.11.6-1.8-0.3-0.31.6-1.41.41.6
Degree of sensitization stereotypy0.00.00.20.0-0.00.5-0.3-0.20.1-0.10.0
Condit. Reinf. active minus inactive responses1.31.42.2-1.51.3-0.91.5-1.10.7-0.7-1.5
Condit. Reinf. active-inactive response ratio1.11.24.3-0.50.0-2.11.8-0.1-1.01.0-0.5
Condit. Reinf. active responses0.70.81.2-1.11.0-0.20.8-0.80.9-1.0-1.1
Condit. Reinf. inactive responses0.91.02.3-0.60.81.2-0.5-0.81.5-1.5-0.6
Incentive salience index mean1.82.13.0-1.71.70.01.0-1.61.6-1.6-1.7
Condit. Reinf. lever presses1.11.42.8-0.81.21.5-0.7-1.01.7-1.7-0.8
Time in familiar zone, hab. session 10.00.00.10.1-0.10.3-0.20.10.2-0.20.1
Time in novel zone, hab. session 10.20.20.9-0.30.2-0.90.6-0.1-0.30.3-0.3
Total zone transitions, hab. session 10.10.10.40.0-0.10.6-0.30.20.2-0.20.0
Total locomotion distance, hab. session 10.60.93.2-0.10.31.8-1.0-0.41.1-1.1-0.1
Locomotion velocity, hab. session 10.40.62.50.1-0.01.6-0.9-0.10.8-0.80.1
Time in familiar zone, hab. session 21.21.31.81.2-1.3-0.4-0.71.2-1.31.31.2
Time in novel zone, hab. session 21.71.72.4-1.51.5-0.71.5-1.21.0-1.0-1.5
Total zone transitions, hab. session 20.81.01.6-0.91.01.2-0.3-0.81.3-1.3-0.9
Total locomotion distance, hab. session 21.01.31.9-1.11.21.0-0.1-1.11.4-1.4-1.1
Locomotion velocity, hab. session 21.41.82.9-1.21.41.5-0.4-1.31.7-1.7-1.2
Novel to familiar place preference ratio0.10.10.5-0.40.2-0.10.7-0.20.2-0.2-0.4
Novelty place preference0.10.10.6-0.40.2-0.40.8-0.10.0-0.0-0.4
Time in novel zone, NPP test0.20.20.9-0.40.2-0.70.9-0.1-0.10.1-0.4
Total zone transitions, NPP test0.50.82.60.6-0.51.6-1.60.30.1-0.10.6
Total locomotion distance, NPP test0.60.93.40.3-0.11.8-1.5-0.10.8-0.80.3
Locomotion velocity, NPP test0.71.03.70.10.11.9-1.5-0.31.0-1.00.1
Pavlov. Cond. lever latency0.50.62.0-0.70.4-1.41.2-0.5-0.10.1-0.7
Pavlov. Cond. magazine entry latency0.91.21.81.4-1.20.4-1.01.3-0.80.81.4
Pavlov. Cond. change in total contacts1.51.62.3-1.41.50.20.6-1.21.5-1.5-1.4
Pavlov. Cond. index score1.01.21.91.4-1.11.0-1.41.2-0.60.61.4
Pavlov. Cond. latency score0.91.11.81.3-1.01.0-1.41.2-0.50.51.3
Pavlov. Cond. lever contacts0.30.41.00.7-0.40.8-1.00.7-0.20.20.7
Pavlov. Cond. magazine entry number0.81.01.7-1.21.1-0.20.7-1.30.9-0.9-1.2
Pavlov. Cond. intertrial magazine entries1.92.36.1-0.30.72.5-1.4-0.92.1-2.1-0.3
Pavlov. Cond. lever-magazine prob. diff.1.11.42.21.5-1.20.9-1.41.4-0.70.71.5
Pavlov. Cond. response bias0.20.30.50.6-0.50.3-0.70.7-0.30.30.6
Bone: apparent density0.00.00.20.2-0.20.5-0.30.00.1-0.10.2
Bone surface0.20.30.4-0.60.50.10.6-0.60.4-0.5-0.6
Bone volume0.20.40.6-0.70.60.20.6-0.80.6-0.6-0.7
Bone: connectivity density0.10.20.40.4-0.60.1-0.20.4-0.60.60.4
Bone: cortical apparent density0.40.60.9-0.90.9-0.40.6-0.80.6-0.6-0.9
Bone: cortical area1.82.84.5-1.92.00.20.7-2.11.8-1.8-1.9
Bone: cortical porosity0.00.00.1-0.10.10.3-0.2-0.20.3-0.3-0.1
Bone: cortical porosity0.10.10.20.4-0.40.3-0.40.2-0.10.10.4
Bone: cortical thickness1.22.03.3-1.61.60.30.3-1.81.6-1.6-1.6
Bone: cortical thickness0.70.82.70.8-0.61.6-1.40.00.5-0.50.8
Bone: cortical tissue density0.50.61.0-1.00.9-0.40.7-0.80.6-0.6-1.0
Bone: elastic displacement0.80.91.60.8-1.1-0.5-0.50.9-1.31.30.8
Bone: elastic work0.10.10.2-0.20.00.3-0.4-0.40.3-0.3-0.2
Bone: endosteal estimation0.10.20.4-0.30.40.60.2-0.50.6-0.6-0.3
Bone: endosteal perimeter0.71.42.6-0.91.31.2-0.2-1.31.6-1.6-0.9
Bone: final force0.40.71.2-1.00.9-0.41.1-0.80.6-0.6-1.0
Bone: final moment0.50.91.3-1.11.0-0.51.1-1.00.7-0.7-1.1
Bone: marrow area0.10.20.4-0.20.30.60.1-0.40.6-0.6-0.2
Bone: maximum diameter3.15.78.3-2.92.8-0.11.8-2.92.3-2.3-2.9
Bone: maximum force0.30.50.8-0.80.80.10.5-0.90.7-0.7-0.8
Bone: maximum moment0.40.71.1-0.91.00.00.5-1.10.8-0.8-0.9
Bone: minimum diameter0.00.10.20.20.10.2-0.50.1-0.20.20.2
Bone: periosteal estimation0.71.42.1-1.21.40.50.4-1.41.4-1.4-1.2
Bone: periosteal perimeter1.52.43.7-1.41.81.00.1-1.91.9-1.9-1.4
Bone: post-yield work0.10.20.3-0.40.40.30.0-0.60.5-0.5-0.4
Bone: stiffness0.00.00.00.20.10.20.00.10.1-0.10.2
Bone: tissue strength0.90.82.9-0.1-0.1-1.71.40.3-0.90.9-0.1
Bone: trabecular number0.00.00.00.1-0.20.10.00.0-0.10.10.1
Bone: trabecular spacing0.60.81.2-1.00.90.30.4-1.11.0-1.0-1.0
Bone: trabecular thickness0.60.81.61.1-0.81.1-1.30.6-0.00.01.1
Bone: trabecular tissue density0.30.40.70.6-0.7-0.50.20.8-0.80.80.6
Breakpoint value in progressive ratio session0.60.61.2-1.10.7-0.60.4-0.90.7-0.7-1.1
Distance traveled before self-admin0.20.20.6-0.40.7-0.20.8-0.20.0-0.0-0.4
Distance traveled after self-admin0.30.40.6-0.50.70.7-0.1-0.50.8-0.8-0.5
Delta time in closed arm before/after self-admin6.46.28.02.8-2.41.0-2.72.8-2.52.52.8
Delta time in open arm before/after self-admin6.66.37.8-2.82.8-1.62.6-2.72.2-2.2-2.8
Diff in mean of infusions in LGA sessions0.20.20.90.5-0.3-0.1-1.00.2-0.40.40.5
Extinction: sum of active levers before priming0.30.40.8-0.80.9-0.70.3-0.20.2-0.2-0.8
Active lever presses in extinction session 60.10.10.5-0.1-0.0-0.3-0.7-0.2-0.00.0-0.1
Delta distance traveled before/after self-admin0.50.51.90.5-0.41.4-1.20.10.3-0.30.5
Delta ambulatory time before/after self-admin0.50.61.60.6-0.81.2-1.30.30.0-0.00.6
Time in closed arm before self-admin0.30.40.9-0.70.2-0.20.9-0.50.7-0.7-0.7
Time in closed arm after self-admin1.61.62.41.5-1.40.8-1.11.6-1.11.11.5
Time in open arm before self-admin2.22.42.91.7-1.71.4-1.71.5-1.31.31.7
Time in open arm after self-admin0.10.10.3-0.40.6-0.40.4-0.10.2-0.2-0.4
Sum of active levers in priming session hrs 5-60.70.71.1-1.10.8-0.50.2-1.00.8-0.8-1.1
Time to tail flick, vehicle, before self-admin0.60.62.90.10.21.3-1.70.20.0-0.00.1
Time to tail flick, vehicle, after self-admin0.30.40.7-0.40.80.9-0.8-0.50.4-0.4-0.4
Time to tail flick, test, before self-admin0.90.81.60.8-1.3-0.80.81.0-0.90.90.8
Time to tail flick, test, after self-admin2.82.94.1-1.72.01.4-0.3-1.62.0-2.0-1.7
Delta time to tail flick, vehicle, before/after SA0.10.10.20.00.20.5-0.2-0.40.2-0.20.0
Delta time to tail flick, test, before/after SA2.22.04.2-1.52.10.5-0.3-1.51.5-1.5-1.5
Ambulatory time before self-admin0.40.41.0-0.71.00.40.5-0.60.5-0.5-0.7
Ambulatory time after self-admin0.40.41.2-0.50.61.1-0.5-0.40.7-0.7-0.5
Total heroin consumption0.50.63.2-0.4-0.3-1.80.20.0-0.60.6-0.4
Area under the delay curve3.73.96.7-1.82.21.5-0.2-2.22.6-2.6-1.8
Delay disc. indifference point, 0s delay0.91.03.1-0.80.90.90.0-1.81.1-1.1-0.8
Delay disc. indifference point, 16s delay2.22.24.3-1.72.10.20.5-1.51.6-1.6-1.7
Delay disc. indifference point, 2s delay2.32.64.3-1.01.22.0-0.8-1.92.1-2.1-1.0
Delay disc. indifference point, 24s delay1.51.52.1-1.41.40.10.5-1.41.4-1.3-1.4
Delay disc. indifference point, 4s delay4.14.37.8-1.71.72.2-0.5-2.42.8-2.8-1.7
Delay disc. indifference point, 8s delay1.61.73.1-0.91.41.5-0.7-1.11.8-1.8-0.9
Delay discount exponential model param3.63.86.91.7-2.1-1.50.32.1-2.62.61.7
Delay discount hyperbolic model param3.94.27.51.7-2.1-1.70.32.3-2.72.71.7
Fecal boli incidents, locomotor time 10.30.30.80.4-0.90.0-0.50.7-0.40.40.4
Change in fecal boli incidents, locomotor task0.70.62.3-0.30.5-1.51.4-0.1-0.20.2-0.3
Time >=10cm from walls, locomotor time 10.40.40.80.7-0.5-0.4-0.20.4-0.90.90.7
Bouts of movement, locomotor time 10.60.62.4-0.8-0.1-0.41.5-1.00.4-0.4-0.8
Total resting periods, locomotor time 10.30.31.5-0.5-0.4-0.51.2-0.60.0-0.0-0.5
Rest time, locomotor task time 10.00.10.1-0.0-0.4-0.30.30.1-0.20.2-0.0
Distance moved, locomotor task time 10.30.31.0-0.51.00.2-0.2-0.30.6-0.6-0.5
Vertical activity count, locomotor time 10.10.10.3-0.10.6-0.00.1-0.20.2-0.2-0.1
Time >=10cm from walls, locomotor time 21.11.23.01.1-0.81.5-1.71.0-0.40.41.1
Bouts of movement, locomotor time 22.22.47.3-0.60.82.7-1.4-1.11.9-1.9-0.6
Total resting periods, locomotor time 22.02.15.4-0.70.92.3-1.0-1.21.9-1.9-0.7
Rest time, locomotor task time 20.50.62.7-0.1-0.2-1.60.80.1-0.80.8-0.1
Distance moved, locomotor task time 20.20.20.90.4-0.10.9-0.50.5-0.10.10.4
Vertical activity count, locomotor time 20.50.50.80.9-0.50.7-0.80.7-0.60.60.9
Weight adjusted by age0.30.30.5-0.50.70.7-0.0-0.70.6-0.6-0.5
Seeking ratio, delayed vs. immediate footshock0.60.72.70.7-0.41.1-1.61.00.0-0.00.7
Locomotion in novel chamber3.74.67.02.7-2.50.9-1.81.6-2.22.22.7
Locomotion in novel chamber post-restriction2.42.84.02.0-1.71.2-1.81.8-1.41.42.0
Progressive ratio0.40.51.00.5-0.2-0.4-1.00.7-0.90.90.5
Food seeking constrained by brief footshock1.92.34.4-1.22.11.4-1.1-1.51.6-1.6-1.2
Seeking ratio, punishment vs. effort1.82.24.1-1.11.41.50.2-1.52.0-2.0-1.1
Run reversals in cocaine runway, females0.70.73.10.6-0.41.8-1.1-0.10.1-0.10.6
Run reversals in cocaine runway, males0.20.20.4-0.50.1-0.60.6-0.20.3-0.3-0.5
Latency to leave start box in cocaine runway0.20.20.7-0.40.1-0.0-0.0-0.80.5-0.5-0.4
Latency to leave start box in cocaine runway, F0.60.72.2-0.70.40.40.1-1.50.9-0.9-0.7
Latency to leave start box in cocaine runway, M0.40.41.00.5-0.6-0.7-0.21.0-0.70.70.5
Cd content in liver0.10.10.20.4-0.3-0.3-0.40.3-0.40.40.4
Co content in liver0.30.40.9-0.60.7-0.80.9-0.50.2-0.2-0.6
Cu content in liver0.50.61.2-0.80.8-1.11.1-0.30.0-0.0-0.8
Fe content in liver0.30.30.70.5-0.6-0.4-0.00.8-0.70.70.5
K content in liver0.80.82.2-0.30.71.5-1.1-0.51.1-1.1-0.3
Mg content in liver0.20.20.4-0.60.70.10.2-0.50.1-0.1-0.6
Mn content in liver0.70.82.0-0.20.61.4-1.0-0.41.2-1.2-0.2
Na content in liver2.93.14.1-2.02.0-0.11.4-2.01.9-1.9-2.0
Rb content in liver1.62.03.8-1.82.0-1.01.2-1.30.8-0.8-1.8
Se content in liver1.31.52.5-1.41.60.10.5-1.31.4-1.4-1.4
Sr content in liver1.51.43.0-1.41.3-0.00.8-1.71.0-1.0-1.4
Zn content in liver0.40.40.8-0.50.90.7-0.4-0.40.8-0.8-0.5