Hub : Genes

Brme1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000025796 0.05 0.03 3.8e-05 0.04 0.03 0.03 0.04 8.4e-05 1.8e-04 2.7e-04 9.0e-05
2 Adipose isoform ratio ENSRNOT00000115206 0.04 0.02 1.2e-04 0.02 0.01 0 0.01 1.8e-03 2.7e-02 1.0e-01 3.5e-02
3 Adipose mRNA stability ENSRNOG00000025796 0.15 0.07 4.0e-10 0.08 0.08 0.07 0.08 6.8e-09 1.5e-09 9.5e-09 6.5e-09
4 BLA gene expression ENSRNOG00000025796 0.28 0.1 1.0e-09 0.14 0.15 0.13 0.16 6.5e-08 1.4e-08 1.4e-07 8.1e-09
5 BLA mRNA stability ENSRNOG00000025796 0.09 0.05 2.9e-03 0.06 0.04 0.04 0.06 4.5e-04 4.0e-03 4.0e-03 4.3e-04
6 Brain gene expression ENSRNOG00000025796 0.04 0.02 1.9e-03 0.04 0.03 0.02 0.04 8.6e-05 6.7e-04 5.0e-03 3.3e-04
7 Brain mRNA stability ENSRNOG00000025796 0.06 0.03 1.4e-04 0.05 0.04 0.04 0.05 2.1e-05 9.2e-05 2.0e-04 4.2e-05
8 Liver gene expression ENSRNOG00000025796 0.05 0.03 1.3e-03 0.03 0.01 0.01 0.01 3.2e-04 2.2e-02 3.6e-02 1.3e-02
9 Liver mRNA stability ENSRNOG00000025796 0.09 0.04 1.9e-10 0.09 0.08 0.08 0.09 4.3e-10 1.7e-09 1.3e-09 5.0e-10
10 PL alternative polyA ENSRNOT00000115303 0.06 0.04 1.9e-03 0.02 0.01 0.01 0.01 1.2e-02 6.6e-02 4.7e-02 4.2e-02
11 PL alternative polyA ENSRNOT00000115206 0.06 0.04 3.7e-03 0.02 0 0.01 0.01 1.1e-02 1.3e-01 4.0e-02 3.9e-02
12 PL alternative polyA ENSRNOT00000115303 0.06 0.04 3.5e-03 0.02 0 0.01 0.01 1.2e-02 1.5e-01 2.9e-02 4.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.62.07.40.02.71.3-0.21.80.22.0-0.12.70.2-0.20.2
BMI without tail0.20.40.70.40.60.70.50.30.80.40.60.80.8-0.80.8
Body weight0.00.20.7-0.80.30.30.4-0.3-0.2-0.2-0.60.6-0.20.2-0.2
Epididymis fat weight0.61.33.3-1.6-0.3-0.8-0.5-0.6-1.4-0.6-1.8-0.2-1.41.4-1.4
Glucose0.10.11.00.2-1.0-0.2-0.3-0.00.3-0.00.20.10.3-0.30.3
Heart weight1.62.25.01.32.21.90.91.31.51.11.61.51.5-1.51.5
Left kidney weight0.30.91.8-1.1-0.2-0.10.9-1.3-0.9-1.4-1.0-1.0-0.90.9-0.9
Right kidney weight0.20.71.5-1.20.50.31.0-1.0-0.7-1.0-1.2-0.3-0.70.7-0.7
Tail length0.92.89.2-0.1-3.0-1.11.4-2.60.2-2.60.3-2.70.2-0.20.2
Length with tail0.51.75.0-0.9-2.2-0.80.6-1.9-0.6-2.0-0.6-2.0-0.60.6-0.6
Length without tail0.40.91.7-1.30.5-0.1-0.90.5-1.20.3-1.30.3-1.21.2-1.2
Liver weight, left2.33.75.9-2.2-0.9-2.2-1.0-1.3-2.4-1.2-1.8-1.5-2.42.4-2.4
Liver weight, right1.11.83.1-1.8-0.8-1.4-0.2-1.3-1.5-1.3-1.5-1.1-1.51.5-1.5
Parametrial fat weight0.30.60.9-0.7-1.0-0.8-0.4-0.7-0.9-0.8-0.7-0.7-0.90.9-0.9
Retroperitoneal fat weight0.51.74.3-2.10.3-0.2-0.1-0.5-1.7-0.6-2.10.5-1.71.7-1.7
Intraocular pressure2.53.56.11.42.22.50.32.21.72.11.82.31.7-1.71.7
Extensor digitorum longus weight0.20.72.0-1.00.60.0-0.70.3-1.00.3-1.40.6-1.01.0-1.0
Soleus weight0.10.31.1-1.10.7-0.0-0.5-0.0-0.60.2-0.60.2-0.60.6-0.6
Tibialis anterior weight0.31.23.01.00.91.71.10.41.20.50.91.01.2-1.21.2
Tibia length0.30.72.50.6-1.6-0.4-0.2-0.21.1-0.20.7-0.51.1-1.11.1
Number of licking bursts0.40.50.8-0.70.4-0.40.7-0.7-0.8-0.9-0.7-0.6-0.80.8-0.8
Food consumed during 24 hour testing period7.69.113.3-2.9-2.3-3.6-0.7-3.1-3.3-2.9-3.3-3.2-3.33.3-3.3
Times rat made contact with spout0.00.00.1-0.10.2-0.3-0.1-0.0-0.20.1-0.1-0.2-0.20.2-0.2
Mean time between licks in bursts0.30.41.90.51.00.91.4-0.10.5-0.10.30.40.5-0.50.5
Mean num. licks in bursts0.50.61.01.0-0.20.3-0.50.71.00.90.90.41.0-1.01.0
Std. dev. time between licks in bursts0.70.82.2-0.5-0.5-0.51.1-1.4-0.7-1.5-0.7-1.2-0.70.7-0.7
Water consumed over 24 hours1.51.83.9-1.4-0.7-2.0-0.6-1.2-1.4-1.1-1.4-1.5-1.41.4-1.4
Indifference point 0 sec0.50.82.41.1-0.41.11.5-0.51.0-0.50.40.51.0-1.01.0
Indifference point AUC1.92.24.7-1.5-1.4-2.2-0.9-1.3-1.5-1.3-1.4-1.7-1.51.5-1.5
Indifference point function ln k3.24.57.32.31.42.71.51.32.41.42.52.02.4-2.42.4
Indifference point function log k3.24.57.32.31.42.71.51.32.41.42.52.02.4-2.42.4
Delay discounting total patch changes 0 sec0.50.81.71.0-0.01.31.3-0.11.0-0.10.40.91.0-1.01.0
Delay discounting total patch changes 12 sec0.81.13.6-0.6-0.8-0.31.4-1.7-0.6-1.9-0.9-1.1-0.60.6-0.6
Delay discounting total patch changes 18 sec2.02.66.0-1.4-1.9-1.80.6-2.5-0.9-2.4-1.5-2.3-0.90.9-0.9
Delay discounting total patch changes 24 sec0.81.03.1-0.2-1.5-0.61.1-1.8-0.5-1.7-0.5-1.3-0.50.5-0.5
Delay discounting total patch changes 6 sec0.40.61.1-0.7-0.8-0.9-0.1-0.9-0.6-1.1-0.9-0.9-0.60.6-0.6
Delay discounting time to switch 0 sec0.10.20.7-0.70.0-0.3-0.0-0.4-0.5-0.4-0.8-0.4-0.50.5-0.5
Delay discounting water rate 0 sec0.00.00.2-0.2-0.4-0.3-0.4-0.0-0.00.0-0.10.2-0.00.0-0.0
Delay discounting water rate 12 sec1.31.94.01.40.81.00.60.71.81.02.00.51.8-1.81.8
Delay discounting water rate 18 sec2.22.95.92.3-0.31.21.70.12.20.12.4-0.12.2-2.22.2
Delay discounting water rate 24 sec1.72.34.02.00.41.51.50.41.90.42.00.71.9-1.91.9
Delay discounting water rate 6 sec1.92.85.9-1.2-2.1-2.30.2-2.3-1.2-2.1-0.9-2.4-1.21.2-1.2
Locomotor activity1.32.03.4-1.80.8-1.3-1.40.3-1.80.1-1.9-0.1-1.81.8-1.8
Locomotor testing distance1.62.74.8-1.80.7-1.6-1.90.4-2.10.2-2.2-0.3-2.12.1-2.1
Locomotor testing rearing2.23.45.4-2.1-0.2-1.8-0.4-1.4-2.2-1.5-2.3-1.7-2.22.2-2.2
Light reinforcement 18.515.530.2-3.4-4.4-4.30.8-5.5-3.2-5.5-3.3-5.0-3.23.2-3.2
Light reinforcement 28.511.317.1-3.0-3.9-3.9-0.1-4.1-3.0-4.1-3.1-4.1-3.03.0-3.0
Reaction time number correct1.82.64.21.81.11.90.91.11.81.22.11.51.8-1.81.8
Reaction time mean minus median0.40.51.50.30.61.1-0.21.00.41.20.41.10.4-0.40.4
Reaction time mean minus median AUC0.91.22.70.71.11.5-0.11.50.61.70.91.60.6-0.60.6
Reaction time num false alarms1.11.55.00.32.22.20.71.20.51.10.52.00.5-0.50.5
Reaction time num false alarms AUC1.31.85.00.82.12.20.71.30.91.21.01.80.9-0.90.9
Reaction time trials correct on left1.82.64.21.81.11.90.91.11.81.22.11.51.8-1.81.8
Reaction time trials on left1.82.53.91.71.21.90.81.21.71.32.01.61.7-1.71.7
Reaction time mean1.72.46.20.52.22.0-0.52.40.62.50.52.50.6-0.60.6
Reaction time mean AUC1.82.36.00.62.11.9-0.52.40.62.40.62.40.6-0.60.6
Median of all reaction times1.92.56.50.52.31.9-0.52.40.62.50.42.60.6-0.60.6
Reaction time omissions0.91.23.0-0.41.71.6-0.61.5-0.31.6-0.51.7-0.30.3-0.3
Reaction time false alarm rate0.20.31.2-0.01.11.00.30.50.10.40.00.80.1-0.10.1
Reaction time premature initiation rate3.14.110.7-0.9-2.9-2.11.4-3.3-0.8-3.2-0.6-3.2-0.80.8-0.8
Reaction time premature initiations1.31.85.5-0.1-2.0-1.01.5-2.30.1-2.20.4-2.00.1-0.10.1
Std. dev. reaction times0.50.72.40.11.11.2-0.41.40.21.60.21.30.2-0.20.2
Reaction time trials completed1.82.53.91.71.21.90.81.21.71.32.01.61.7-1.71.7
Reaction time trials AUC1.72.43.61.61.31.90.71.31.61.31.91.71.6-1.61.6
Social response proportion0.70.81.3-0.81.00.4-0.60.5-1.10.5-0.90.9-1.11.1-1.1
Social responses0.60.81.5-0.81.20.10.3-0.2-1.2-0.2-0.80.1-1.21.2-1.2
Social time0.20.31.10.7-0.20.31.0-0.40.3-0.40.5-0.70.3-0.30.3
Conditioned locomotion0.10.10.2-0.4-0.4-0.3-0.0-0.4-0.4-0.4-0.4-0.3-0.40.4-0.4
Cocaine response after cond. corrected0.70.81.4-1.10.7-0.2-0.70.4-1.20.4-1.00.7-1.21.2-1.2
Cocaine response after cond. not corrected1.51.63.2-1.40.7-0.6-1.10.3-1.80.3-1.40.6-1.81.8-1.8
Cocaine response before conditioning0.20.20.5-0.1-0.4-0.50.2-0.6-0.5-0.6-0.1-0.7-0.50.5-0.5
Saline control response3.95.27.8-2.8-0.8-2.1-0.4-2.1-2.8-2.0-2.8-1.6-2.82.8-2.8
Condit. Reinf. active minus inactive responses0.30.40.90.5-0.70.20.9-0.60.8-0.60.5-0.20.8-0.80.8
Condit. Reinf. active-inactive response ratio0.00.10.10.2-0.10.2-0.20.30.20.20.10.30.2-0.20.2
Condit. Reinf. active responses0.10.10.4-0.3-0.5-0.30.3-0.60.2-0.60.0-0.30.2-0.20.2
Condit. Reinf. inactive responses0.20.31.1-1.00.1-0.7-0.8-0.1-0.50.0-0.50.1-0.50.5-0.5
Condit. Reinf. lever presses0.10.10.3-0.10.2-0.2-0.50.40.50.40.10.20.5-0.50.5
Condit. Reinf. lever reinforcers received0.10.10.2-0.2-0.5-0.40.0-0.40.4-0.40.1-0.20.4-0.40.4
Pavlov. Cond. lever latency0.30.30.8-0.20.20.50.10.1-0.90.2-0.40.5-0.90.9-0.9
Pavlov. Cond. magazine entry latency0.00.00.20.00.10.30.4-0.10.2-0.20.1-0.00.2-0.20.2
Pavlov. Cond. change in total contacts0.60.81.90.9-0.20.20.40.11.4-0.01.1-0.21.4-1.41.4
Pavlov. Cond. index score0.30.41.00.5-0.3-0.10.10.01.0-0.10.7-0.41.0-1.01.0
Pavlov. Cond. latency score0.30.40.90.5-0.3-0.10.2-0.01.0-0.20.7-0.41.0-1.01.0
Pavlov. Cond. lever contacts0.10.20.5-0.3-0.2-0.7-0.3-0.20.4-0.3-0.0-0.60.4-0.40.4
Pavlov. Cond. magazine entry number0.20.30.7-0.40.1-0.3-0.3-0.0-0.80.0-0.60.0-0.80.8-0.8
Pavlov. Cond. intertrial magazine entries1.21.63.5-1.0-1.2-1.10.7-1.9-1.0-1.8-1.1-1.5-1.01.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.00.5-0.10.00.20.11.00.00.7-0.21.0-1.01.0
Pavlov. Cond. response bias0.20.20.6-0.0-0.1-0.3-0.20.10.7-0.10.2-0.20.7-0.70.7
Conditioned reinforcement - actives0.00.00.1-0.10.10.1-0.20.2-0.00.2-0.00.1-0.00.0-0.0
Conditioned reinforcement - inactives0.20.20.40.40.10.40.30.40.60.30.60.10.6-0.60.6
Conditioned locomotion0.10.20.30.40.30.10.30.20.60.30.50.20.6-0.60.6
Intermittent access intake day 1-15 change1.11.13.6-0.5-1.4-1.00.9-1.5-0.6-1.5-0.3-1.9-0.60.6-0.6
Intermittent access intake escalation1.61.64.3-0.7-1.6-1.30.7-1.7-0.9-1.6-0.6-2.1-0.90.9-0.9
Intermittent access intake escalation 21.21.23.9-0.0-1.6-1.01.1-1.7-0.4-1.5-0.1-2.0-0.40.4-0.4
Intermitt. access day 1 inactive lever presses1.21.32.51.4-0.60.30.8-0.21.6-0.31.5-0.11.6-1.61.6
Intermitt. access day 15 inactive lever presses0.10.10.5-0.20.3-0.1-0.50.6-0.20.7-0.30.3-0.20.2-0.2
Intermitt. access escalation Index0.20.20.5-0.4-0.4-0.70.1-0.5-0.4-0.5-0.4-0.5-0.40.4-0.4
Intermittent access day 1 total infusions0.60.72.00.31.00.6-0.71.30.61.30.41.40.6-0.60.6
Intermittent access day 15 total infusions0.00.00.10.1-0.3-0.00.1-0.00.20.00.2-0.20.2-0.20.2
Intermittent access terminal intake (last 3 days)0.10.10.20.3-0.10.20.10.20.40.20.40.00.4-0.40.4
Intermittent access total infusions0.10.10.30.10.20.2-0.20.50.30.50.30.40.3-0.30.3
Intermittent access day 1 locomotion0.60.61.10.70.70.2-0.10.90.90.90.81.10.9-0.90.9
Intermittent access day 15 total locomotion0.60.61.1-0.80.6-0.4-1.10.8-0.80.9-0.70.7-0.80.8-0.8
Intermittent access total locomotion0.50.61.6-0.60.9-0.2-1.11.1-0.41.3-0.41.2-0.40.4-0.4
Intermittent access standard deviation1.41.52.51.5-0.30.81.5-0.21.6-0.11.5-0.61.6-1.61.6
Cocaine induced anxiety0.20.20.30.4-0.10.50.30.20.60.20.60.20.6-0.60.6
Post-drug Anxiety0.60.61.40.41.21.1-0.01.20.51.20.50.90.5-0.50.5
Baseline Anxiety1.01.11.8-1.30.6-0.4-1.10.4-1.30.4-1.30.3-1.31.3-1.3
Lifetime Intake0.10.10.20.10.00.2-0.10.40.40.40.30.30.4-0.40.4
Incentive Sensitization - Responses0.10.10.20.5-0.00.50.4-0.00.50.10.4-0.20.5-0.50.5
Incentive Sensitization - Breakpoint0.20.20.20.5-0.10.50.4-0.10.50.10.4-0.20.5-0.50.5
Progressive ratio test 1 active lever presses0.70.72.20.11.00.6-0.91.40.21.30.21.50.2-0.20.2
Progressive ratio test 1 breakpoint0.60.61.80.20.90.6-0.71.30.31.20.31.40.3-0.30.3
Progressive ratio test 1 inactive lever presses0.20.20.40.3-0.30.1-0.20.40.70.30.50.30.7-0.70.7
Progressive ratio test 2 active lever presses0.40.41.00.40.70.7-0.30.90.51.00.50.90.5-0.50.5
Progressive ratio test 2 breakpoint0.40.41.20.10.90.6-0.61.00.21.10.21.00.2-0.20.2
Progressive ratio test 2 inactive lever presses0.80.92.60.31.20.8-0.71.60.51.60.41.30.5-0.50.5
Total sessions with >9 infusions3.23.55.42.01.01.70.41.62.31.62.31.82.3-2.32.3
Short access day 1 total inactive lever presses0.30.41.2-0.7-1.1-0.8-0.5-0.4-0.4-0.4-0.5-0.6-0.40.4-0.4
Short access day 10 total inactive lever presses0.80.92.50.5-1.6-0.70.8-1.20.7-1.20.6-1.10.7-0.70.7
Short access day 1 total infusions2.42.63.41.60.71.5-0.11.71.81.61.91.81.8-1.81.8
Short access day 10 total infusions0.10.10.3-0.6-0.2-0.6-0.60.1-0.20.1-0.40.0-0.20.2-0.2
Short access total infusions0.10.10.20.1-0.10.2-0.30.50.50.40.30.40.5-0.50.5
Short access day 1 locomotion1.31.42.41.20.71.1-0.41.41.21.41.31.51.2-1.21.2
Short access day 10 total locomotion0.70.71.40.81.10.4-0.01.10.71.20.91.20.7-0.70.7
Short access total locomotion1.81.82.61.41.00.90.11.41.51.41.61.51.5-1.51.5
Compulsive drug intake1.81.83.11.6-0.60.61.8-0.71.6-0.71.7-0.61.6-1.61.6
One hour access (0.3 mA shock)0.00.00.10.10.10.20.20.20.10.20.30.10.1-0.10.1
One hour access (shock baseline)0.60.71.2-0.71.10.1-1.01.0-0.81.1-0.70.9-0.80.8-0.8
Number of responses in last shaping day2.42.43.11.51.01.6-0.11.61.71.61.71.61.7-1.71.7
Context. condit. distance diff. score0.80.93.00.31.71.60.51.00.21.00.31.60.2-0.20.2
Locomotion velocity, session 10.80.92.1-0.6-1.4-1.40.2-1.40.0-1.3-0.1-1.50.0-0.00.0
Locomotion distance, session 10.50.61.4-1.2-0.2-0.90.2-1.0-0.6-1.1-1.2-0.7-0.60.6-0.6
Locomotion velocity, session 20.30.31.1-0.7-0.3-0.70.3-1.0-0.1-0.9-0.3-1.0-0.10.1-0.1
Locomotion distance, session 20.50.71.7-1.30.6-0.40.1-0.5-1.0-0.6-1.30.0-1.01.0-1.0
Locomotion velocity, session 30.30.30.70.7-0.00.40.30.20.70.20.80.20.7-0.70.7
Locomotion distance, session 31.11.24.71.4-0.21.12.2-0.81.0-0.81.1-0.41.0-1.01.0
Stereotopy head waving bouts, day 32.93.56.32.20.21.50.91.02.51.02.50.92.5-2.52.5
Stereotopy head waving duration, day 31.51.83.31.10.71.10.40.91.80.91.70.81.8-1.81.8
Locomotion velocity, session 70.30.41.00.50.91.01.00.20.30.20.50.70.3-0.30.3
Locomotion distance, session 70.20.30.7-0.80.1-0.40.1-0.7-0.6-0.5-0.7-0.3-0.60.6-0.6
Stereotopy head waving bouts, day 71.92.23.81.6-0.31.11.8-0.41.9-0.51.9-0.41.9-1.91.9
Stereotopy head waving duration, day 71.01.32.31.2-0.50.61.5-0.61.3-0.71.5-0.71.3-1.31.3
Locomotion velocity, session 80.10.10.6-0.8-0.2-0.20.3-0.6-0.1-0.5-0.50.0-0.10.1-0.1
Locomotion distance, session 80.40.51.6-0.91.30.40.5-0.1-0.7-0.1-1.00.7-0.70.7-0.7
Degree of sensitization distance1.41.43.2-1.80.2-1.1-1.60.1-1.40.2-1.50.2-1.41.4-1.4
Degree of sensitization stereotypy1.21.32.41.20.21.11.4-0.11.5-0.21.5-0.01.5-1.51.5
Condit. Reinf. active minus inactive responses3.94.411.82.01.63.43.10.22.10.32.01.62.1-2.12.1
Condit. Reinf. active-inactive response ratio1.51.66.90.71.92.61.80.40.70.50.61.60.7-0.70.7
Condit. Reinf. active responses2.42.96.81.70.92.52.6-0.21.8-0.12.00.81.8-1.81.8
Condit. Reinf. inactive responses0.91.13.10.1-1.8-1.00.7-1.60.4-1.50.6-1.70.4-0.40.4
Incentive salience index mean3.03.79.42.00.12.33.1-0.72.3-0.62.10.22.3-2.32.3
Condit. Reinf. lever presses1.92.54.61.7-1.50.62.1-1.31.8-1.31.7-1.21.8-1.81.8
Time in familiar zone, hab. session 10.30.31.00.10.10.31.0-0.80.5-0.70.5-0.50.5-0.50.5
Time in novel zone, hab. session 10.70.72.80.20.6-0.4-1.71.5-0.21.5-0.20.8-0.20.2-0.2
Total zone transitions, hab. session 10.71.02.3-1.3-0.5-1.5-1.0-0.6-0.9-0.6-1.3-0.9-0.90.9-0.9
Total locomotion distance, hab. session 10.30.41.8-0.9-0.3-1.4-0.9-0.3-0.3-0.3-0.7-0.6-0.30.3-0.3
Locomotion velocity, hab. session 10.50.72.3-1.2-0.6-1.5-0.7-0.7-0.6-0.7-1.0-0.8-0.60.6-0.6
Time in familiar zone, hab. session 20.60.62.2-0.5-0.8-0.60.9-1.5-0.0-1.4-0.3-1.2-0.00.0-0.0
Time in novel zone, hab. session 21.61.64.0-0.12.00.8-1.32.0-0.52.0-0.21.9-0.50.5-0.5
Total zone transitions, hab. session 20.50.61.8-0.8-0.4-1.10.6-1.3-0.1-1.3-0.6-1.2-0.10.1-0.1
Total locomotion distance, hab. session 20.50.61.4-1.2-0.4-1.1-0.0-1.0-0.6-1.0-0.9-0.8-0.60.6-0.6
Locomotion velocity, hab. session 20.50.71.6-1.2-0.7-1.3-0.2-1.0-0.5-1.1-1.0-0.9-0.50.5-0.5
Novel to familiar place preference ratio0.60.61.6-0.41.2-0.1-1.01.0-0.81.0-0.60.7-0.80.8-0.8
Novelty place preference1.01.01.7-0.71.2-0.4-1.31.0-1.11.0-0.90.6-1.11.1-1.1
Time in novel zone, NPP test0.90.92.1-0.31.3-0.2-1.51.3-0.71.3-0.50.8-0.70.7-0.7
Total zone transitions, NPP test0.71.03.0-1.0-0.9-0.80.9-1.7-0.4-1.7-1.1-1.1-0.40.4-0.4
Total locomotion distance, NPP test0.10.20.5-0.5-0.2-0.50.3-0.7-0.0-0.7-0.6-0.5-0.00.0-0.0
Locomotion velocity, NPP test0.30.41.3-0.8-0.4-0.40.7-1.1-0.3-1.1-0.9-0.5-0.30.3-0.3
Pavlov. Cond. lever latency1.11.42.8-1.30.6-0.9-0.7-0.2-1.6-0.3-1.7-0.2-1.61.6-1.6
Pavlov. Cond. magazine entry latency1.11.42.11.30.40.8-0.21.21.41.31.40.91.4-1.41.4
Pavlov. Cond. change in total contacts1.21.32.21.2-1.20.41.1-0.61.5-0.51.5-0.41.5-1.51.5
Pavlov. Cond. index score1.62.03.91.7-0.11.20.70.71.90.82.00.71.9-1.91.9
Pavlov. Cond. latency score1.01.32.71.3-0.30.90.70.31.50.41.60.41.5-1.51.5
Pavlov. Cond. lever contacts1.11.32.51.2-0.60.60.20.41.60.51.60.31.6-1.61.6
Pavlov. Cond. magazine entry number2.22.84.6-2.2-0.1-1.3-0.4-1.3-2.1-1.3-2.1-1.1-2.12.1-2.1
Pavlov. Cond. intertrial magazine entries1.51.83.80.9-0.51.42.0-0.91.7-0.71.30.11.7-1.71.7
Pavlov. Cond. lever-magazine prob. diff.1.82.33.81.8-0.01.20.41.11.91.12.01.01.9-1.91.9
Pavlov. Cond. response bias2.02.44.11.9-0.11.00.01.22.01.32.00.82.0-2.02.0
Bone: apparent density1.62.68.4-0.7-2.2-2.5-0.3-1.9-0.8-1.9-1.2-2.9-0.80.8-0.8
Bone surface1.22.17.10.7-2.7-1.41.0-2.00.5-2.00.2-2.40.5-0.50.5
Bone volume1.42.38.40.3-2.9-1.90.5-2.00.2-2.0-0.3-2.70.2-0.20.2
Bone: connectivity density1.93.011.1-0.2-2.5-2.30.6-2.4-0.2-2.5-0.5-3.3-0.20.2-0.2
Bone: cortical apparent density0.71.02.21.01.51.31.00.70.90.70.80.70.9-0.90.9
Bone: cortical area0.20.20.8-0.4-0.20.20.8-0.9-0.2-0.9-0.4-0.2-0.20.2-0.2
Bone: cortical porosity0.30.30.8-0.10.20.8-0.70.7-0.30.70.00.9-0.30.3-0.3
Bone: cortical porosity0.20.21.20.30.01.10.20.40.10.30.30.80.1-0.10.1
Bone: cortical thickness0.50.83.4-0.11.81.50.50.80.10.80.01.60.1-0.10.1
Bone: cortical thickness3.23.88.2-2.91.9-1.2-1.80.3-2.30.2-2.60.2-2.32.3-2.3
Bone: cortical tissue density0.81.01.81.11.31.31.20.61.00.60.90.61.0-1.01.0
Bone: elastic displacement1.31.52.41.30.71.41.10.61.50.61.21.11.5-1.51.5
Bone: elastic work0.81.02.80.61.41.30.31.20.81.20.41.70.8-0.80.8
Bone: endosteal estimation0.81.82.5-1.4-0.8-1.5-0.3-1.3-1.5-1.3-1.6-1.2-1.51.5-1.5
Bone: endosteal perimeter0.71.44.3-0.4-1.7-0.51.4-2.1-0.5-2.1-0.6-1.4-0.50.5-0.5
Bone: final force0.50.81.5-1.1-0.5-0.8-0.5-0.5-1.1-0.5-1.2-0.3-1.11.1-1.1
Bone: final moment0.30.51.2-1.0-0.2-0.6-0.3-0.4-0.9-0.4-1.1-0.2-0.90.9-0.9
Bone: marrow area0.81.72.5-1.5-0.8-1.5-0.3-1.2-1.5-1.2-1.6-1.1-1.51.5-1.5
Bone: maximum diameter0.40.72.70.7-0.50.91.6-0.90.8-0.90.7-0.10.8-0.80.8
Bone: maximum force0.20.30.6-0.6-0.5-0.4-0.2-0.4-0.7-0.4-0.8-0.1-0.70.7-0.7
Bone: maximum moment0.10.20.4-0.5-0.3-0.30.0-0.4-0.5-0.4-0.7-0.0-0.50.5-0.5
Bone: minimum diameter1.32.44.0-1.2-1.7-1.60.3-2.0-1.5-2.0-1.5-1.8-1.51.5-1.5
Bone: periosteal estimation0.81.62.7-1.4-0.9-1.10.3-1.6-1.3-1.6-1.5-1.3-1.31.3-1.3
Bone: periosteal perimeter0.61.03.7-0.2-0.80.31.9-1.8-0.1-1.8-0.2-0.8-0.10.1-0.1
Bone: post-yield work1.31.72.8-1.2-1.1-1.7-0.9-0.9-1.5-0.9-1.3-1.4-1.51.5-1.5
Bone: stiffness1.11.72.6-1.5-1.0-1.3-1.4-0.5-1.6-0.5-1.5-0.5-1.61.6-1.6
Bone: tissue strength0.70.71.71.00.41.30.80.50.80.50.90.90.8-0.80.8
Bone: trabecular number1.52.49.40.4-2.7-2.10.2-1.80.3-1.9-0.1-3.10.3-0.30.3
Bone: trabecular spacing1.41.86.40.02.31.8-0.31.8-0.01.80.22.5-0.00.0-0.0
Bone: trabecular thickness0.91.13.3-0.8-1.3-1.8-1.0-0.7-0.9-0.6-1.1-1.3-0.90.9-0.9
Bone: trabecular tissue density1.21.64.1-0.91.30.2-2.01.7-1.01.8-0.81.5-1.01.0-1.0
Breakpoint value in progressive ratio session3.94.48.5-2.90.5-1.5-2.10.3-2.70.3-2.70.3-2.72.7-2.7
Distance traveled before self-admin0.20.31.00.00.40.3-1.00.9-0.10.9-0.20.5-0.10.1-0.1
Distance traveled after self-admin0.30.31.30.30.50.1-0.91.00.21.10.20.20.2-0.20.2
Delta time in closed arm before/after self-admin1.11.12.40.91.11.50.21.01.01.00.81.41.0-1.01.0
Delta time in open arm before/after self-admin5.04.87.3-2.7-1.7-2.4-0.3-2.1-2.4-2.2-2.5-1.8-2.42.4-2.4
Diff in mean of infusions in LGA sessions0.30.40.9-0.9-0.4-0.8-0.4-0.6-0.6-0.6-0.9-0.3-0.60.6-0.6
Extinction: sum of active levers before priming2.02.04.01.21.61.40.21.31.41.41.32.01.4-1.41.4
Active lever presses in extinction session 61.61.53.01.5-0.11.11.40.31.60.21.70.11.6-1.61.6
Delta distance traveled before/after self-admin0.10.10.10.30.1-0.10.10.20.30.20.40.10.3-0.30.3
Delta ambulatory time before/after self-admin0.20.20.50.4-0.4-0.30.7-0.40.4-0.40.5-0.70.4-0.40.4
Time in closed arm before self-admin0.30.41.21.1-0.5-0.40.4-0.30.5-0.30.8-0.90.5-0.50.5
Time in closed arm after self-admin0.20.20.70.80.30.8-0.10.40.40.40.50.40.4-0.40.4
Time in open arm before self-admin1.11.22.60.71.11.60.21.21.01.20.91.31.0-1.01.0
Time in open arm after self-admin0.30.31.1-1.00.3-0.3-0.30.2-0.60.1-0.70.4-0.60.6-0.6
Sum of active levers in priming session hrs 5-60.40.41.0-1.0-0.3-0.70.1-0.8-0.6-0.8-0.7-0.5-0.60.6-0.6
Time to tail flick, vehicle, before self-admin0.40.51.3-0.3-0.9-1.2-0.8-0.8-0.4-0.7-0.5-0.7-0.40.4-0.4
Time to tail flick, vehicle, after self-admin3.03.25.5-2.1-0.7-1.3-1.0-1.3-2.3-1.4-2.2-0.9-2.32.3-2.3
Time to tail flick, test, before self-admin0.50.51.7-0.00.80.9-0.51.3-0.11.3-0.01.1-0.10.1-0.1
Time to tail flick, test, after self-admin0.20.20.4-0.5-0.2-0.2-0.2-0.3-0.5-0.4-0.6-0.3-0.50.5-0.5
Delta time to tail flick, vehicle, before/after SA0.60.61.0-0.9-0.5-0.00.3-0.7-1.0-0.8-0.9-0.5-1.01.0-1.0
Delta time to tail flick, test, before/after SA0.10.00.20.10.10.20.4-0.20.2-0.30.0-0.20.2-0.20.2
Ambulatory time before self-admin0.50.51.5-0.30.60.2-1.21.1-0.41.2-0.40.8-0.40.4-0.4
Ambulatory time after self-admin0.20.20.7-0.2-0.0-0.5-0.80.4-0.30.5-0.3-0.5-0.30.3-0.3
Total heroin consumption0.50.61.5-1.20.5-0.4-0.30.1-1.00.0-0.90.3-1.01.0-1.0
Area under the delay curve0.30.30.60.50.40.60.20.20.80.20.70.50.8-0.80.8
Delay disc. indifference point, 0s delay0.50.62.0-0.1-1.4-1.2-0.3-1.10.2-1.10.2-0.90.2-0.20.2
Delay disc. indifference point, 16s delay0.50.51.2-0.61.10.2-1.00.9-0.40.9-0.31.1-0.40.4-0.4
Delay disc. indifference point, 2s delay0.80.91.41.01.01.2-0.21.20.91.10.80.90.9-0.90.9
Delay disc. indifference point, 24s delay0.90.93.00.60.81.71.00.50.80.50.91.20.8-0.80.8
Delay disc. indifference point, 4s delay0.40.40.70.7-0.6-0.40.0-0.50.7-0.60.7-0.90.7-0.70.7
Delay disc. indifference point, 8s delay0.80.81.30.60.71.00.50.31.20.31.01.01.2-1.21.2
Delay discount exponential model param0.50.50.8-0.7-0.6-0.9-0.4-0.3-0.9-0.2-0.9-0.5-0.90.9-0.9
Delay discount hyperbolic model param0.50.50.9-0.7-0.6-0.9-0.4-0.2-0.9-0.2-0.9-0.5-0.90.9-0.9
Fecal boli incidents, locomotor time 11.21.34.5-0.2-2.1-0.41.1-1.6-0.4-1.8-0.3-1.7-0.40.4-0.4
Change in fecal boli incidents, locomotor task0.60.61.10.9-0.0-0.10.5-0.41.0-0.41.1-0.41.0-1.01.0
Time >=10cm from walls, locomotor time 10.20.20.6-0.20.3-0.6-0.80.2-0.50.1-0.5-0.7-0.50.5-0.5
Bouts of movement, locomotor time 10.70.71.50.90.10.70.50.31.10.41.20.11.1-1.11.1
Total resting periods, locomotor time 11.41.52.81.40.41.30.80.61.60.71.70.41.6-1.61.6
Rest time, locomotor task time 11.61.82.91.50.41.71.30.71.60.71.70.61.6-1.61.6
Distance moved, locomotor task time 11.41.62.7-1.30.3-1.3-1.60.2-1.60.2-1.50.1-1.61.6-1.6
Vertical activity count, locomotor time 15.55.77.9-2.6-1.5-2.6-1.8-1.8-2.8-1.8-2.8-1.9-2.82.8-2.8
Time >=10cm from walls, locomotor time 20.50.52.8-0.10.4-0.1-1.71.2-0.11.2-0.00.8-0.10.1-0.1
Bouts of movement, locomotor time 20.50.61.40.61.20.6-0.51.00.61.10.50.80.6-0.60.6
Total resting periods, locomotor time 20.20.20.80.30.90.3-0.60.70.20.80.10.40.2-0.20.2
Rest time, locomotor task time 20.20.20.7-0.2-0.4-0.40.1-0.6-0.3-0.6-0.3-0.9-0.30.3-0.3
Distance moved, locomotor task time 20.91.03.0-0.21.20.6-1.21.7-0.01.70.01.7-0.00.0-0.0
Vertical activity count, locomotor time 21.21.43.4-1.8-0.6-1.1-0.9-0.9-1.3-0.9-1.4-0.5-1.31.3-1.3
Weight adjusted by age0.30.41.00.30.80.3-0.91.0-0.10.90.01.0-0.10.1-0.1
Seeking ratio, delayed vs. immediate footshock1.01.23.80.52.01.2-0.21.40.71.50.61.50.7-0.70.7
Locomotion in novel chamber1.92.34.2-1.81.3-0.6-1.10.5-2.00.3-2.00.7-2.02.0-2.0
Locomotion in novel chamber post-restriction0.20.21.50.4-0.6-1.2-0.3-0.20.2-0.20.3-0.50.2-0.20.2
Progressive ratio0.60.71.0-0.9-0.2-0.6-0.1-0.9-1.0-0.9-0.9-0.8-1.01.0-1.0
Food seeking constrained by brief footshock1.01.33.4-0.2-1.7-0.81.0-1.8-0.4-1.9-0.3-1.8-0.40.4-0.4
Seeking ratio, punishment vs. effort0.30.31.00.6-1.00.00.7-0.30.6-0.40.5-0.50.6-0.60.6
Run reversals in cocaine runway, females1.11.12.2-1.30.70.4-1.21.0-1.01.0-1.11.5-1.01.0-1.0
Run reversals in cocaine runway, males0.40.41.30.61.20.6-0.61.10.11.10.10.20.1-0.10.1
Latency to leave start box in cocaine runway1.21.32.7-1.60.4-0.4-0.90.4-1.50.2-1.70.3-1.51.5-1.5
Latency to leave start box in cocaine runway, F0.70.72.2-0.70.3-0.5-1.50.9-0.90.8-0.90.7-0.90.9-0.9
Latency to leave start box in cocaine runway, M2.92.85.0-2.2-0.8-1.00.4-1.6-2.0-1.6-2.2-1.2-2.02.0-2.0
Cd content in liver0.70.83.50.90.71.41.9-0.40.6-0.31.00.30.6-0.60.6
Co content in liver4.14.88.12.51.22.91.81.32.51.32.61.82.5-2.52.5
Cu content in liver0.40.52.10.31.31.41.10.4-0.00.30.10.9-0.00.0-0.0
Fe content in liver1.21.43.01.6-1.20.30.20.21.60.21.7-0.11.6-1.61.6
K content in liver0.10.10.2-0.00.0-0.3-0.20.30.30.30.10.50.3-0.30.3
Mg content in liver0.80.81.70.90.10.50.50.61.30.51.00.81.3-1.31.3
Mn content in liver0.10.10.6-0.2-0.20.10.8-0.40.3-0.5-0.30.10.3-0.30.3
Na content in liver0.60.72.6-0.7-0.6-1.6-1.50.1-0.7-0.1-0.4-0.4-0.70.7-0.7
Rb content in liver0.10.20.40.5-0.40.20.6-0.20.5-0.30.3-0.20.5-0.50.5
Se content in liver1.61.94.31.0-2.1-0.11.0-1.01.7-1.11.4-0.91.7-1.71.7
Sr content in liver0.30.31.10.20.51.00.80.40.10.4-0.30.90.1-0.10.1
Zn content in liver0.60.71.8-0.41.31.10.50.4-0.90.3-0.70.8-0.90.9-0.9