Crk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000025792 0.02 0.01 5.3e-03 0 0 -0 0 7.3e-02 1.2e-01 4.8e-01 1.7e-01
2 BLA gene expression ENSRNOG00000025792 0.12 0.08 1.4e-04 0.03 0.06 0.05 0.05 1.2e-02 2.8e-04 8.6e-04 1.4e-03
3 Brain gene expression ENSRNOG00000025792 0.33 0.12 0.0e+00 0.23 0.23 0.23 0.23 9.0e-21 8.0e-21 9.9e-21 4.9e-21
4 LHb gene expression ENSRNOG00000025792 0.25 0.13 7.8e-04 0.17 0.04 0.08 -0.01 8.3e-05 3.8e-02 6.9e-03 9.3e-01
5 Liver gene expression ENSRNOG00000025792 0.05 0.03 4.3e-04 0.03 0.01 0.01 0.01 7.4e-04 1.5e-02 8.8e-03 6.8e-03
6 NAcc gene expression ENSRNOG00000025792 0.23 0.11 1.7e-12 0.18 0.17 0.17 0.18 4.3e-13 4.9e-13 6.7e-13 3.0e-13
7 OFC gene expression ENSRNOG00000025792 0.24 0.14 6.0e-04 0.2 0.11 0.09 0.07 2.2e-05 1.3e-03 3.1e-03 1.1e-02
8 PL gene expression ENSRNOG00000025792 0.15 0.08 1.6e-08 0.11 0.11 0.11 0.1 1.3e-08 2.1e-08 1.8e-08 3.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.23.84.60.91.92.12.12.11.92.12.1
BMI without tail0.20.40.80.90.90.50.40.40.50.50.5
Body weight1.04.29.73.12.91.81.71.61.31.61.7
Epididymis fat weight3.37.711.02.83.32.82.72.72.42.62.7
Glucose3.55.36.3-2.0-2.5-2.3-2.3-2.3-2.3-2.4-2.3
Heart weight0.10.10.70.90.50.20.20.1-0.10.10.1
Left kidney weight3.510.114.4-0.2-2.2-3.5-3.4-3.5-3.8-3.5-3.6
Right kidney weight2.88.111.50.1-1.8-3.2-3.1-3.1-3.4-3.2-3.2
Tail length0.82.511.03.31.3-0.9-1.1-1.1-1.2-1.1-1.0
Length with tail0.41.59.23.01.6-0.2-0.3-0.3-0.5-0.3-0.2
Length without tail0.91.93.61.91.91.21.21.20.91.11.2
Liver weight, left0.50.83.01.70.5-0.7-0.8-0.8-0.6-0.8-0.8
Liver weight, right0.30.42.71.60.8-0.1-0.2-0.2-0.0-0.2-0.1
Parametrial fat weight6.612.821.64.44.73.33.13.13.03.43.4
Retroperitoneal fat weight0.00.00.20.20.0-0.1-0.1-0.2-0.4-0.0-0.1
Intraocular pressure0.50.71.9-1.4-0.40.70.80.80.60.80.8
Extensor digitorum longus weight6.325.430.92.04.55.65.55.55.25.55.5
Soleus weight3.19.115.03.73.92.82.82.72.52.62.8
Tibialis anterior weight10.034.641.03.05.76.46.36.36.06.36.2
Tibia length0.72.02.41.3-0.1-1.5-1.5-1.6-1.5-1.5-1.6
Number of licking bursts0.40.50.8-0.4-0.7-0.7-0.7-0.7-0.9-0.6-0.7
Food consumed during 24 hour testing period0.30.30.40.60.60.60.50.50.60.60.5
Times rat made contact with spout1.71.92.50.2-0.9-1.5-1.6-1.6-1.5-1.6-1.5
Mean time between licks in bursts0.20.31.41.20.5-0.2-0.3-0.3-0.6-0.3-0.2
Mean num. licks in bursts0.10.20.30.60.1-0.4-0.4-0.4-0.1-0.5-0.4
Std. dev. time between licks in bursts0.40.50.70.40.60.80.80.80.60.70.8
Water consumed over 24 hours0.50.60.80.9-0.0-0.8-0.8-0.8-0.8-0.9-0.9
Indifference point 0 sec0.20.30.50.10.50.60.60.60.70.60.5
Indifference point AUC0.20.31.6-1.3-0.7-0.1-0.0-0.1-0.20.00.0
Indifference point function ln k0.71.01.20.91.11.00.91.01.10.91.0
Indifference point function log k0.71.01.20.91.11.00.91.01.10.91.0
Delay discounting total patch changes 0 sec0.20.40.6-0.00.50.70.70.70.80.60.6
Delay discounting total patch changes 12 sec0.50.70.8-0.6-0.8-0.8-0.8-0.9-0.9-0.8-0.9
Delay discounting total patch changes 18 sec0.91.22.0-0.6-0.9-1.2-1.2-1.2-1.4-1.1-1.1
Delay discounting total patch changes 24 sec0.81.01.2-1.0-1.1-0.9-0.9-0.9-1.1-1.0-1.0
Delay discounting total patch changes 6 sec0.10.21.5-1.2-0.50.00.10.10.10.0-0.0
Delay discounting time to switch 0 sec1.42.22.90.2-0.8-1.7-1.7-1.7-1.6-1.7-1.7
Delay discounting water rate 0 sec0.50.81.2-0.50.31.11.11.10.91.01.0
Delay discounting water rate 12 sec0.00.00.00.20.10.20.20.20.10.10.1
Delay discounting water rate 18 sec3.44.55.61.22.02.42.32.32.12.22.2
Delay discounting water rate 24 sec0.30.40.8-0.20.30.70.70.80.60.70.9
Delay discounting water rate 6 sec0.10.10.5-0.7-0.6-0.2-0.2-0.1-0.2-0.2-0.1
Locomotor activity0.00.10.10.30.30.30.30.2-0.10.30.2
Locomotor testing distance0.00.00.10.10.20.20.20.10.00.30.2
Locomotor testing rearing0.40.61.0-0.20.50.90.90.90.71.01.0
Light reinforcement 10.00.00.1-0.20.10.20.10.1-0.10.30.3
Light reinforcement 22.83.75.2-0.7-1.7-2.1-2.1-2.1-2.3-2.0-2.0
Reaction time number correct0.00.10.20.50.30.00.00.10.10.30.3
Reaction time mean minus median0.10.21.0-1.0-0.40.20.10.20.10.10.2
Reaction time mean minus median AUC1.21.52.0-0.40.71.41.31.41.31.41.4
Reaction time num false alarms0.60.81.6-1.3-0.10.80.81.00.80.90.9
Reaction time num false alarms AUC0.50.71.6-1.2-0.20.80.80.90.70.90.8
Reaction time trials correct on left0.00.10.20.50.30.00.00.10.10.30.3
Reaction time trials on left0.00.10.20.40.30.10.10.10.10.30.3
Reaction time mean0.10.10.2-0.5-0.5-0.3-0.3-0.2-0.1-0.4-0.3
Reaction time mean AUC0.20.30.7-0.8-0.8-0.4-0.4-0.3-0.2-0.4-0.4
Median of all reaction times0.20.30.4-0.3-0.6-0.6-0.6-0.5-0.4-0.7-0.7
Reaction time omissions0.00.00.0-0.2-0.2-0.1-0.2-0.20.0-0.1-0.1
Reaction time false alarm rate0.40.61.4-1.2-0.10.80.80.90.80.80.7
Reaction time premature initiation rate0.60.81.00.30.81.01.00.91.00.91.0
Reaction time premature initiations0.71.01.30.50.91.01.01.01.01.11.2
Std. dev. reaction times0.10.20.8-0.9-0.40.30.20.30.40.20.2
Reaction time trials completed0.00.10.20.40.30.10.10.10.10.30.3
Reaction time trials AUC0.00.10.20.40.30.10.00.10.10.30.3
Social response proportion1.21.35.42.31.70.60.60.50.70.70.6
Social responses1.21.53.01.71.71.01.11.00.81.21.1
Social time2.63.45.12.02.31.71.71.81.71.91.8
Conditioned locomotion0.30.30.8-0.6-0.9-0.6-0.6-0.6-0.2-0.6-0.5
Cocaine response after cond. corrected0.10.10.30.60.3-0.1-0.1-0.10.1-0.1-0.2
Cocaine response after cond. not corrected0.20.20.80.90.80.30.30.30.40.20.1
Cocaine response before conditioning1.21.41.80.81.31.31.31.31.01.21.3
Saline control response0.70.91.3-0.00.81.11.11.10.81.11.0
Condit. Reinf. active minus inactive responses0.40.50.70.40.70.70.70.70.60.80.9
Condit. Reinf. active-inactive response ratio0.10.10.20.3-0.1-0.5-0.5-0.5-0.3-0.3-0.3
Condit. Reinf. active responses1.11.52.70.01.01.31.31.31.01.61.6
Condit. Reinf. inactive responses3.03.75.5-0.51.22.22.22.21.62.32.3
Condit. Reinf. lever presses0.30.32.2-1.5-0.7-0.00.00.0-0.30.10.1
Condit. Reinf. lever reinforcers received1.01.42.5-0.20.91.31.31.30.91.51.6
Pavlov. Cond. lever latency1.21.62.41.61.51.21.21.21.31.11.1
Pavlov. Cond. magazine entry latency1.41.72.5-0.4-1.0-1.3-1.3-1.3-1.6-1.5-1.5
Pavlov. Cond. change in total contacts1.01.31.9-0.9-1.1-1.2-1.2-1.2-1.4-1.2-1.1
Pavlov. Cond. index score1.62.12.8-1.5-1.6-1.4-1.4-1.4-1.7-1.4-1.4
Pavlov. Cond. latency score1.92.43.0-1.7-1.7-1.4-1.4-1.4-1.7-1.5-1.5
Pavlov. Cond. lever contacts0.91.21.7-1.0-1.1-1.1-1.1-1.1-1.3-1.1-1.1
Pavlov. Cond. magazine entry number1.61.92.60.61.21.41.41.41.61.61.6
Pavlov. Cond. intertrial magazine entries2.63.34.30.91.71.91.91.91.92.12.1
Pavlov. Cond. lever-magazine prob. diff.1.51.92.4-1.4-1.5-1.3-1.3-1.3-1.5-1.4-1.3
Pavlov. Cond. response bias1.31.92.5-1.0-1.3-1.4-1.4-1.4-1.6-1.4-1.4
Conditioned reinforcement - actives2.92.83.80.31.31.81.91.91.91.81.8
Conditioned reinforcement - inactives0.70.81.2-0.40.61.10.90.91.11.11.0
Conditioned locomotion0.10.10.8-0.9-0.4-0.1-0.1-0.1-0.3-0.1-0.1
Intermittent access intake day 1-15 change0.60.62.1-1.5-0.50.50.70.70.70.50.5
Intermittent access intake escalation0.60.53.0-1.7-1.1-0.2-0.1-0.1-0.1-0.2-0.2
Intermittent access intake escalation 21.01.03.3-1.8-1.5-0.6-0.6-0.6-0.6-0.7-0.7
Intermitt. access day 1 inactive lever presses2.93.13.9-1.5-2.0-1.7-1.9-1.9-1.7-1.7-1.7
Intermitt. access day 15 inactive lever presses0.60.72.0-1.4-1.1-0.7-0.7-0.7-0.6-0.6-0.6
Intermitt. access escalation Index1.41.27.72.81.4-0.2-0.2-0.2-0.1-0.3-0.3
Intermittent access day 1 total infusions0.70.81.00.00.81.01.01.00.81.01.0
Intermittent access day 15 total infusions1.11.31.5-1.20.31.21.21.21.11.21.2
Intermittent access terminal intake (last 3 days)1.92.02.7-0.21.11.61.61.61.51.61.6
Intermittent access total infusions0.70.81.1-0.90.40.91.01.00.90.90.9
Intermittent access day 1 locomotion0.40.40.6-0.6-0.5-0.7-0.6-0.6-0.8-0.6-0.6
Intermittent access day 15 total locomotion0.30.31.7-1.3-0.7-0.2-0.2-0.2-0.4-0.2-0.1
Intermittent access total locomotion0.10.10.7-0.8-0.3-0.1-0.0-0.0-0.1-0.1-0.1
Intermittent access standard deviation1.01.16.2-2.5-1.10.50.50.50.70.40.4
Cocaine induced anxiety0.20.21.1-1.0-0.40.30.40.40.30.40.4
Post-drug Anxiety0.20.20.3-0.40.20.50.60.60.40.60.6
Baseline Anxiety0.00.00.20.50.2-0.1-0.2-0.2-0.1-0.2-0.2
Lifetime Intake0.70.81.0-1.00.30.91.01.01.00.90.9
Incentive Sensitization - Responses0.20.20.2-0.40.10.40.40.40.50.50.5
Incentive Sensitization - Breakpoint0.10.10.1-0.40.00.30.30.30.30.30.3
Progressive ratio test 1 active lever presses0.40.40.6-0.00.60.70.80.80.60.60.6
Progressive ratio test 1 breakpoint0.90.91.30.31.01.01.11.11.01.01.0
Progressive ratio test 1 inactive lever presses0.50.51.7-1.3-0.9-0.6-0.6-0.6-0.5-0.5-0.6
Progressive ratio test 2 active lever presses0.50.50.7-0.60.30.70.90.90.80.80.8
Progressive ratio test 2 breakpoint0.50.60.9-0.70.20.70.90.90.90.70.7
Progressive ratio test 2 inactive lever presses0.30.31.5-1.2-0.30.40.30.30.40.40.3
Total sessions with >9 infusions0.10.20.2-0.30.30.30.50.50.50.40.4
Short access day 1 total inactive lever presses0.20.20.30.20.60.50.40.40.60.40.4
Short access day 10 total inactive lever presses0.40.50.8-0.0-0.4-0.7-0.9-0.9-0.6-0.7-0.8
Short access day 1 total infusions0.40.42.4-1.6-0.60.20.30.30.40.30.3
Short access day 10 total infusions1.01.11.5-0.50.61.21.21.21.21.21.2
Short access total infusions0.60.71.6-1.3-0.00.70.90.90.90.80.8
Short access day 1 locomotion0.20.21.4-1.2-0.6-0.2-0.0-0.0-0.1-0.1-0.1
Short access day 10 total locomotion0.50.60.9-1.0-0.9-0.8-0.7-0.7-0.6-0.7-0.7
Short access total locomotion0.30.31.7-1.3-0.6-0.2-0.2-0.2-0.1-0.2-0.2
Compulsive drug intake0.20.20.91.00.2-0.5-0.3-0.3-0.3-0.4-0.3
One hour access (0.3 mA shock)1.82.13.0-0.60.81.51.71.71.61.61.6
One hour access (shock baseline)1.11.31.6-0.80.51.31.31.31.21.31.2
Number of responses in last shaping day1.01.02.6-1.6-1.2-0.8-0.7-0.7-0.7-0.8-0.8
Context. condit. distance diff. score1.21.51.91.01.41.31.31.31.31.21.2
Locomotion velocity, session 12.93.14.82.12.21.61.61.61.61.61.7
Locomotion distance, session 10.91.11.50.41.01.21.21.20.91.21.2
Locomotion velocity, session 20.80.91.30.61.01.01.01.00.81.01.1
Locomotion distance, session 22.02.83.40.81.61.81.81.81.51.81.8
Locomotion velocity, session 35.26.07.4-1.2-2.3-2.6-2.6-2.6-2.7-2.6-2.6
Locomotion distance, session 30.10.10.2-0.5-0.10.20.20.20.10.20.2
Stereotopy head waving bouts, day 30.20.20.60.80.1-0.5-0.5-0.5-0.5-0.4-0.2
Stereotopy head waving duration, day 30.30.30.7-0.5-0.6-0.6-0.6-0.6-0.9-0.4-0.3
Locomotion velocity, session 71.31.41.80.41.01.31.31.31.31.31.3
Locomotion distance, session 72.12.73.60.61.41.81.81.81.91.71.7
Stereotopy head waving bouts, day 70.80.91.41.01.20.90.90.90.51.11.2
Stereotopy head waving duration, day 71.31.62.21.21.51.21.21.20.81.41.4
Locomotion velocity, session 80.60.71.1-0.10.70.90.90.90.81.01.0
Locomotion distance, session 82.23.24.61.52.11.91.81.81.51.81.8
Degree of sensitization distance1.11.11.51.21.21.01.01.01.10.91.0
Degree of sensitization stereotypy1.21.32.11.31.51.01.01.00.71.21.2
Condit. Reinf. active minus inactive responses0.30.30.50.3-0.2-0.7-0.7-0.7-0.7-0.5-0.5
Condit. Reinf. active-inactive response ratio3.03.24.40.4-1.0-2.0-2.0-2.1-2.0-2.0-2.0
Condit. Reinf. active responses0.30.40.60.40.50.50.60.50.70.70.7
Condit. Reinf. inactive responses4.55.37.7-0.21.42.52.62.62.82.52.6
Incentive salience index mean0.20.20.40.60.0-0.5-0.5-0.6-0.5-0.4-0.4
Condit. Reinf. lever presses0.30.41.91.41.00.20.20.10.30.30.3
Time in familiar zone, hab. session 11.71.62.3-0.60.51.51.51.51.51.31.4
Time in novel zone, hab. session 11.61.62.30.3-0.6-1.5-1.5-1.5-1.5-1.3-1.3
Total zone transitions, hab. session 12.43.44.7-0.31.32.12.12.11.52.12.2
Total locomotion distance, hab. session 10.81.11.50.30.91.21.21.20.71.21.2
Locomotion velocity, hab. session 10.91.31.80.10.91.31.41.40.91.31.3
Time in familiar zone, hab. session 22.52.63.40.31.31.81.81.81.61.71.7
Time in novel zone, hab. session 25.85.87.4-0.8-2.0-2.7-2.7-2.7-2.5-2.6-2.6
Total zone transitions, hab. session 21.21.62.00.61.31.41.41.40.91.41.4
Total locomotion distance, hab. session 20.10.10.30.40.50.40.40.40.10.40.4
Locomotion velocity, hab. session 20.10.10.20.30.40.30.30.30.00.30.3
Novel to familiar place preference ratio0.10.10.4-0.6-0.5-0.00.00.00.2-0.1-0.2
Novelty place preference0.00.00.1-0.3-0.3-0.0-0.0-0.00.2-0.1-0.2
Time in novel zone, NPP test0.00.00.2-0.00.00.20.20.20.40.10.0
Total zone transitions, NPP test1.42.02.80.01.11.61.71.70.91.61.7
Total locomotion distance, NPP test0.40.50.7-0.60.30.80.90.90.20.80.8
Locomotion velocity, NPP test0.20.31.1-1.0-0.30.40.50.5-0.00.50.5
Pavlov. Cond. lever latency0.30.40.6-0.50.10.70.80.80.70.60.6
Pavlov. Cond. magazine entry latency0.20.31.41.20.70.20.10.10.50.20.1
Pavlov. Cond. change in total contacts0.80.81.1-0.4-0.8-1.0-1.0-1.1-1.0-0.9-0.9
Pavlov. Cond. index score0.20.21.21.10.6-0.1-0.2-0.2-0.0-0.1-0.1
Pavlov. Cond. latency score0.20.31.51.20.5-0.4-0.4-0.4-0.3-0.3-0.3
Pavlov. Cond. lever contacts0.20.30.40.5-0.0-0.6-0.6-0.6-0.5-0.5-0.5
Pavlov. Cond. magazine entry number0.10.10.5-0.7-0.4-0.1-0.1-0.1-0.3-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.3-0.70.20.91.10.90.50.91.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.90.60.0-0.0-0.00.10.10.0
Pavlov. Cond. response bias0.10.10.60.80.50.10.00.00.20.10.1
Bone: apparent density4.67.68.61.92.82.92.92.92.82.82.8
Bone surface4.17.28.81.52.63.03.02.92.62.72.9
Bone volume4.57.69.11.52.73.03.03.02.72.83.0
Bone: connectivity density6.710.512.31.93.23.53.53.53.43.33.4
Bone: cortical apparent density0.20.31.2-1.1-0.8-0.2-0.1-0.2-0.1-0.2-0.2
Bone: cortical area1.82.73.4-1.2-1.8-1.7-1.6-1.7-1.6-1.8-1.7
Bone: cortical porosity0.10.10.20.40.40.30.30.30.40.30.4
Bone: cortical porosity0.00.00.00.20.1-0.1-0.0-0.10.0-0.1-0.0
Bone: cortical thickness5.99.812.0-1.5-3.0-3.4-3.3-3.4-3.2-3.5-3.3
Bone: cortical thickness1.41.62.30.1-0.9-1.4-1.4-1.5-1.3-1.5-1.5
Bone: cortical tissue density0.10.20.9-1.0-0.6-0.00.0-0.00.1-0.1-0.0
Bone: elastic displacement0.30.31.0-1.0-0.9-0.4-0.4-0.4-0.4-0.4-0.4
Bone: elastic work4.66.07.0-1.3-2.4-2.6-2.6-2.6-2.6-2.6-2.6
Bone: endosteal estimation0.10.20.3-0.10.30.60.50.60.40.50.6
Bone: endosteal perimeter0.91.92.6-0.30.81.61.61.61.51.51.6
Bone: final force0.91.42.20.5-0.5-1.3-1.3-1.3-1.4-1.5-1.3
Bone: final moment0.71.21.80.4-0.6-1.1-1.1-1.2-1.3-1.3-1.2
Bone: marrow area0.10.20.3-0.10.30.50.50.50.30.50.6
Bone: maximum diameter0.10.30.9-0.9-0.30.40.40.40.60.30.4
Bone: maximum force1.01.72.50.1-0.8-1.4-1.3-1.4-1.6-1.6-1.5
Bone: maximum moment0.81.42.1-0.0-0.8-1.2-1.2-1.2-1.4-1.4-1.3
Bone: minimum diameter1.01.82.5-0.2-1.0-1.4-1.4-1.4-1.5-1.6-1.5
Bone: periosteal estimation0.30.60.8-0.6-0.9-0.7-0.7-0.8-0.8-0.9-0.8
Bone: periosteal perimeter0.10.10.6-0.8-0.5-0.00.0-0.00.0-0.1-0.0
Bone: post-yield work0.20.30.91.00.80.40.40.30.20.30.4
Bone: stiffness0.50.82.51.61.40.70.70.70.50.50.7
Bone: tissue strength2.72.63.4-0.7-1.4-1.7-1.7-1.7-1.8-1.7-1.7
Bone: trabecular number5.07.79.01.62.83.03.03.02.82.92.9
Bone: trabecular spacing0.81.01.2-0.8-1.1-1.1-1.1-1.1-0.9-0.9-1.0
Bone: trabecular thickness0.40.40.60.50.70.70.80.70.70.60.6
Bone: trabecular tissue density2.53.54.2-1.4-2.1-2.0-2.0-1.9-1.8-1.9-1.9
Breakpoint value in progressive ratio session0.60.72.21.51.30.60.60.60.40.60.5
Distance traveled before self-admin1.92.02.5-1.2-1.6-1.4-1.4-1.4-1.5-1.4-1.5
Distance traveled after self-admin0.10.10.30.2-0.1-0.4-0.5-0.5-0.3-0.4-0.3
Delta time in closed arm before/after self-admin0.20.20.6-0.8-0.7-0.3-0.3-0.4-0.3-0.2-0.1
Delta time in open arm before/after self-admin0.70.71.41.01.20.80.70.70.40.70.7
Diff in mean of infusions in LGA sessions0.20.31.41.20.70.1-0.00.00.20.00.1
Extinction: sum of active levers before priming2.02.02.60.71.51.51.51.41.41.51.6
Active lever presses in extinction session 61.31.31.60.81.21.21.21.21.01.21.2
Delta distance traveled before/after self-admin1.31.42.91.71.50.91.00.91.21.01.1
Delta ambulatory time before/after self-admin1.01.12.21.51.40.80.80.81.10.91.0
Time in closed arm before self-admin1.82.03.71.91.91.21.21.31.21.21.1
Time in closed arm after self-admin0.10.10.1-0.0-0.2-0.3-0.3-0.3-0.2-0.3-0.3
Time in open arm before self-admin5.86.28.4-2.2-2.9-2.5-2.5-2.6-2.3-2.5-2.4
Time in open arm after self-admin1.11.21.5-1.1-1.2-1.0-1.1-1.1-1.1-1.1-1.0
Sum of active levers in priming session hrs 5-61.41.42.71.61.61.01.00.81.01.11.0
Time to tail flick, vehicle, before self-admin6.36.48.02.02.82.62.62.42.62.62.6
Time to tail flick, vehicle, after self-admin1.11.21.9-0.10.61.21.21.21.11.31.4
Time to tail flick, test, before self-admin0.60.60.90.40.70.80.81.00.80.80.8
Time to tail flick, test, after self-admin0.10.10.50.70.50.10.10.10.20.10.1
Delta time to tail flick, vehicle, before/after SA0.60.62.0-1.4-1.2-0.6-0.5-0.4-0.5-0.5-0.4
Delta time to tail flick, test, before/after SA0.00.00.1-0.00.00.20.20.10.30.20.2
Ambulatory time before self-admin2.72.83.6-0.9-1.6-1.7-1.7-1.7-1.9-1.7-1.9
Ambulatory time after self-admin0.40.41.41.20.4-0.6-0.6-0.6-0.5-0.6-0.5
Total heroin consumption3.03.65.82.12.41.71.71.81.71.71.8
Area under the delay curve2.02.12.9-1.0-1.4-1.4-1.6-1.6-1.7-1.5-1.5
Delay disc. indifference point, 0s delay0.10.10.10.40.20.2-0.2-0.2-0.30.30.3
Delay disc. indifference point, 16s delay0.91.01.3-0.9-1.0-0.9-1.0-1.0-1.1-0.9-0.9
Delay disc. indifference point, 2s delay1.41.61.9-1.1-1.3-1.2-1.3-1.2-1.4-1.3-1.3
Delay disc. indifference point, 24s delay0.30.30.5-0.5-0.6-0.5-0.6-0.5-0.7-0.6-0.6
Delay disc. indifference point, 4s delay1.41.52.2-0.5-1.0-1.2-1.5-1.4-1.5-1.2-1.2
Delay disc. indifference point, 8s delay1.01.11.4-0.7-0.9-1.0-1.1-1.1-1.2-1.1-1.1
Delay discount exponential model param2.02.12.80.81.31.51.61.61.71.51.5
Delay discount hyperbolic model param1.92.02.70.91.41.41.61.51.61.41.4
Fecal boli incidents, locomotor time 10.10.10.20.30.40.20.40.40.20.10.2
Change in fecal boli incidents, locomotor task0.80.71.1-0.0-0.6-0.9-1.1-1.1-0.8-1.0-0.9
Time >=10cm from walls, locomotor time 10.20.20.3-0.50.20.50.40.40.50.60.5
Bouts of movement, locomotor time 10.10.10.30.00.30.30.40.40.60.40.4
Total resting periods, locomotor time 10.20.20.5-0.20.20.30.40.40.70.40.5
Rest time, locomotor task time 10.20.20.8-0.9-0.30.10.30.30.50.20.3
Distance moved, locomotor task time 10.10.10.2-0.10.20.30.30.30.30.40.2
Vertical activity count, locomotor time 10.80.81.10.40.91.01.00.90.91.11.0
Time >=10cm from walls, locomotor time 21.01.01.3-0.7-0.9-1.0-1.1-1.2-1.1-1.0-1.0
Bouts of movement, locomotor time 20.20.20.3-0.2-0.4-0.5-0.5-0.6-0.3-0.5-0.5
Total resting periods, locomotor time 20.00.00.0-0.0-0.0-0.2-0.1-0.20.1-0.1-0.2
Rest time, locomotor task time 20.30.30.60.00.30.50.60.60.80.60.6
Distance moved, locomotor task time 20.20.31.4-1.2-0.6-0.1-0.2-0.3-0.50.10.0
Vertical activity count, locomotor time 20.40.50.8-0.5-0.7-0.7-0.7-0.7-0.9-0.6-0.6
Weight adjusted by age0.91.01.20.51.01.11.11.11.11.11.1
Seeking ratio, delayed vs. immediate footshock1.21.43.1-1.8-1.5-1.0-0.9-0.9-1.3-0.9-0.9
Locomotion in novel chamber1.31.67.9-2.8-2.0-0.5-0.5-0.5-0.4-0.5-0.5
Locomotion in novel chamber post-restriction0.20.20.3-0.40.10.50.50.50.60.50.5
Progressive ratio0.60.70.8-0.70.20.90.90.90.80.90.9
Food seeking constrained by brief footshock0.10.10.2-0.4-0.4-0.3-0.3-0.3-0.4-0.3-0.3
Seeking ratio, punishment vs. effort1.01.31.60.3-0.7-1.3-1.3-1.3-1.3-1.3-1.3
Run reversals in cocaine runway, females0.20.21.4-1.2-0.60.10.10.1-0.20.10.1
Run reversals in cocaine runway, males0.40.40.6-0.40.10.70.70.70.80.70.7
Latency to leave start box in cocaine runway0.20.20.30.0-0.3-0.5-0.5-0.5-0.5-0.5-0.5
Latency to leave start box in cocaine runway, F0.20.20.40.2-0.1-0.5-0.5-0.5-0.6-0.5-0.5
Latency to leave start box in cocaine runway, M0.00.00.10.40.1-0.2-0.2-0.2-0.1-0.1-0.1
Cd content in liver1.11.21.50.41.01.21.21.21.01.21.1
Co content in liver0.20.20.3-0.3-0.4-0.5-0.5-0.5-0.6-0.4-0.5
Cu content in liver1.21.42.0-0.2-0.9-1.3-1.3-1.3-1.2-1.3-1.4
Fe content in liver0.20.21.11.00.4-0.3-0.4-0.4-0.3-0.3-0.4
K content in liver1.01.01.50.90.0-1.0-1.1-1.1-1.2-1.0-1.0
Mg content in liver0.00.00.1-0.3-0.2-0.1-0.0-0.0-0.1-0.00.0
Mn content in liver0.30.40.50.10.60.70.70.70.60.70.7
Na content in liver3.73.94.9-0.7-1.7-2.2-2.2-2.2-2.2-2.1-2.0
Rb content in liver1.62.02.6-0.01.01.61.61.61.61.61.6
Se content in liver1.21.51.9-0.4-1.1-1.3-1.3-1.3-1.3-1.3-1.4
Sr content in liver1.00.91.10.50.91.01.01.01.01.01.0
Zn content in liver0.70.71.2-0.00.51.01.01.01.10.90.9