Abhd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000025689 0.09 0.1 1.8e-07 0.06 0.06 0.06 0.06 3.7e-07 1.9e-07 2.1e-07 1.9e-07
2 BLA gene expression ENSRNOG00000025689 0.13 0.14 1.4e-03 0.03 0.04 0.03 0.03 1.5e-02 5.0e-03 7.5e-03 1.0e-02
3 Brain gene expression ENSRNOG00000025689 0.03 0.02 2.3e-03 0.02 0.02 0.02 0.02 6.6e-03 3.9e-03 4.6e-03 4.4e-03
4 Liver gene expression ENSRNOG00000025689 0.03 0.03 4.6e-03 0.01 0.01 0 0.01 2.0e-02 3.5e-02 1.1e-01 3.5e-02
5 Liver mRNA stability ENSRNOG00000025689 0.04 0.04 4.3e-04 0.03 0.03 0.03 0.03 1.8e-04 2.3e-04 2.2e-04 2.2e-04
6 NAcc mRNA stability ENSRNOG00000025689 0.04 0.03 1.9e-03 0.02 0.03 0.01 0.01 1.1e-02 4.5e-03 2.4e-02 2.8e-02
7 PL gene expression ENSRNOG00000025689 0.13 0.1 3.8e-05 0.04 0.04 0.04 0.03 8.2e-04 3.6e-04 3.9e-04 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.93.07.3-2.02.01.4-1.2-2.71.40.3
BMI without tail0.10.30.5-0.60.60.5-0.4-0.70.60.3
Body weight1.97.99.5-2.93.02.9-2.5-3.12.92.3
Epididymis fat weight14.233.136.2-6.05.95.9-5.5-5.86.05.2
Glucose0.20.20.3-0.50.50.5-0.5-0.40.50.4
Heart weight8.311.915.5-3.53.43.6-3.9-2.43.53.6
Left kidney weight0.10.20.90.3-0.20.1-0.20.90.00.6
Right kidney weight1.02.94.9-1.51.61.9-1.9-0.71.82.2
Tail length0.10.20.80.2-0.10.3-0.20.60.30.9
Length with tail1.13.96.9-1.71.82.2-2.0-1.02.22.6
Length without tail0.71.51.7-1.31.31.3-1.3-1.01.31.3
Liver weight, left1.21.92.4-1.31.51.5-1.3-1.21.51.3
Liver weight, right8.614.315.6-3.93.93.9-3.9-3.23.93.6
Parametrial fat weight7.113.916.9-4.04.13.7-3.5-4.13.72.8
Retroperitoneal fat weight23.477.494.5-9.59.28.8-8.2-9.78.97.0
Intraocular pressure6.18.59.3-3.03.13.0-2.9-2.83.02.7
Extensor digitorum longus weight3.715.017.93.8-3.8-4.14.22.6-4.1-4.2
Soleus weight3.510.211.43.2-3.2-3.33.42.5-3.4-3.3
Tibialis anterior weight2.68.914.22.6-2.7-3.23.31.2-3.2-3.8
Tibia length2.05.76.5-2.42.42.5-2.5-1.82.52.6
Number of licking bursts0.30.41.5-0.50.70.20.2-1.20.2-0.5
Food consumed during 24 hour testing period0.10.20.50.2-0.0-0.30.6-0.2-0.3-0.7
Times rat made contact with spout1.51.72.61.3-1.1-1.31.60.8-1.3-1.5
Mean time between licks in bursts2.63.63.9-1.92.02.0-1.9-1.52.01.9
Mean num. licks in bursts0.50.61.70.9-1.0-0.70.51.3-0.7-0.1
Std. dev. time between licks in bursts0.40.41.3-0.70.90.5-0.2-1.20.5-0.1
Water consumed over 24 hours1.01.22.70.9-0.6-1.01.50.1-1.1-1.6
Indifference point 0 sec0.50.81.6-1.00.90.8-0.7-1.30.80.5
Indifference point AUC1.82.15.01.1-1.0-1.51.8-0.0-1.5-2.2
Indifference point function ln k0.40.62.50.7-0.6-0.1-0.11.6-0.10.7
Indifference point function log k0.40.62.50.7-0.6-0.1-0.11.6-0.10.7
Delay discounting total patch changes 0 sec0.50.71.7-1.00.90.8-0.6-1.30.80.4
Delay discounting total patch changes 12 sec0.91.21.7-1.31.21.1-1.0-1.31.10.7
Delay discounting total patch changes 18 sec0.30.41.5-0.60.60.20.0-1.20.2-0.5
Delay discounting total patch changes 24 sec0.81.11.7-1.11.11.0-0.9-1.31.00.6
Delay discounting total patch changes 6 sec0.50.73.1-0.90.80.4-0.2-1.80.4-0.5
Delay discounting time to switch 0 sec0.00.10.2-0.40.20.2-0.3-0.40.20.0
Delay discounting water rate 0 sec0.20.20.60.7-0.5-0.30.40.8-0.30.2
Delay discounting water rate 12 sec1.11.73.6-1.01.01.4-1.5-0.31.41.9
Delay discounting water rate 18 sec0.50.72.3-0.00.10.6-0.91.10.61.5
Delay discounting water rate 24 sec1.42.04.1-1.11.21.5-1.6-0.41.62.0
Delay discounting water rate 6 sec0.91.33.5-0.80.81.2-1.40.21.21.9
Locomotor activity0.40.71.1-0.81.00.9-0.6-1.00.90.5
Locomotor testing distance0.10.10.5-0.20.1-0.10.2-0.7-0.1-0.6
Locomotor testing rearing0.71.21.61.1-1.1-1.11.30.5-1.1-1.2
Light reinforcement 12.74.910.41.7-1.8-2.42.40.4-2.5-3.2
Light reinforcement 22.63.45.81.5-1.7-2.01.81.0-2.1-2.4
Reaction time number correct0.40.60.80.7-0.7-0.80.90.5-0.8-0.9
Reaction time mean minus median0.10.10.30.3-0.2-0.10.00.5-0.10.1
Reaction time mean minus median AUC0.00.00.1-0.00.10.2-0.30.20.20.3
Reaction time num false alarms0.70.94.1-1.00.80.3-0.0-2.00.3-0.8
Reaction time num false alarms AUC0.70.94.2-0.90.90.30.0-2.00.2-0.9
Reaction time trials correct on left0.40.60.80.7-0.7-0.80.90.5-0.8-0.9
Reaction time trials on left0.40.60.90.8-0.7-0.80.90.5-0.8-0.9
Reaction time mean0.91.22.9-0.70.81.1-1.40.21.11.7
Reaction time mean AUC0.81.02.5-0.60.71.0-1.30.31.01.6
Median of all reaction times1.01.43.2-0.80.91.2-1.50.21.21.8
Reaction time omissions0.10.10.3-0.00.0-0.20.4-0.4-0.2-0.6
Reaction time false alarm rate0.91.34.8-1.31.20.7-0.5-2.20.7-0.3
Reaction time premature initiation rate0.20.30.3-0.50.50.5-0.5-0.50.50.5
Reaction time premature initiations0.00.00.0-0.10.10.10.0-0.20.1-0.0
Std. dev. reaction times0.20.30.7-0.30.40.6-0.60.10.60.8
Reaction time trials completed0.40.60.90.8-0.7-0.80.90.5-0.8-0.9
Reaction time trials AUC0.60.81.10.8-0.8-0.91.00.6-0.9-1.1
Social response proportion0.20.20.60.10.10.4-0.20.50.40.8
Social responses0.10.10.3-0.20.40.30.2-0.50.30.1
Social time0.10.20.60.10.20.4-0.20.40.40.7
Conditioned locomotion3.64.35.22.3-2.2-2.12.12.3-2.0-1.6
Cocaine response after cond. corrected0.50.60.90.7-0.6-0.70.90.4-0.8-1.0
Cocaine response after cond. not corrected1.31.41.81.2-1.1-1.21.30.9-1.3-1.3
Cocaine response before conditioning1.61.92.71.5-1.6-1.41.21.6-1.4-0.9
Saline control response0.81.01.21.1-1.0-1.01.10.9-1.0-0.8
Condit. Reinf. active minus inactive responses3.34.15.21.8-2.1-2.22.21.1-2.2-2.3
Condit. Reinf. active-inactive response ratio0.90.91.10.9-1.0-1.01.00.7-1.0-1.0
Condit. Reinf. active responses2.63.64.91.7-2.0-2.12.10.9-2.0-2.2
Condit. Reinf. inactive responses1.31.72.61.1-1.2-1.41.50.4-1.4-1.6
Condit. Reinf. lever presses1.72.42.81.6-1.6-1.61.71.2-1.6-1.5
Condit. Reinf. lever reinforcers received2.33.24.41.6-1.9-2.02.00.8-1.9-2.1
Pavlov. Cond. lever latency1.62.22.6-1.61.41.5-1.6-1.21.51.5
Pavlov. Cond. magazine entry latency0.30.30.70.5-0.4-0.60.60.1-0.6-0.8
Pavlov. Cond. change in total contacts0.40.60.90.8-0.7-0.80.90.4-0.8-0.9
Pavlov. Cond. index score1.01.31.71.2-1.0-1.21.30.8-1.2-1.2
Pavlov. Cond. latency score1.01.31.61.2-1.0-1.21.30.8-1.2-1.2
Pavlov. Cond. lever contacts0.71.01.31.1-0.9-1.01.10.7-1.0-1.0
Pavlov. Cond. magazine entry number0.10.10.3-0.30.10.3-0.40.10.30.6
Pavlov. Cond. intertrial magazine entries3.44.44.9-2.22.12.1-2.1-2.02.22.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.30.9-0.8-1.01.10.5-0.9-1.1
Pavlov. Cond. response bias1.31.82.31.4-1.2-1.41.50.9-1.4-1.5
Conditioned reinforcement - actives2.92.96.12.0-1.8-1.51.42.5-1.5-0.8
Conditioned reinforcement - inactives3.94.46.82.3-2.2-2.01.82.6-2.1-1.6
Conditioned locomotion1.62.05.21.7-1.6-1.01.12.3-1.0-0.0
Intermittent access intake day 1-15 change0.60.61.80.9-0.7-0.50.41.3-0.6-0.1
Intermittent access intake escalation0.30.31.00.6-0.4-0.30.21.0-0.40.0
Intermittent access intake escalation 20.10.10.3-0.40.40.4-0.5-0.30.30.2
Intermitt. access day 1 inactive lever presses0.10.10.20.3-0.4-0.40.30.2-0.4-0.5
Intermitt. access day 15 inactive lever presses7.48.213.72.5-2.6-3.13.01.5-3.1-3.7
Intermitt. access escalation Index0.90.82.8-1.01.00.5-0.4-1.70.5-0.4
Intermittent access day 1 total infusions5.56.36.72.6-2.6-2.62.52.3-2.6-2.4
Intermittent access day 15 total infusions3.33.75.52.1-2.0-1.91.72.4-1.9-1.5
Intermittent access terminal intake (last 3 days)3.03.25.12.0-1.8-1.71.62.3-1.8-1.3
Intermittent access total infusions3.64.07.12.3-2.1-1.81.82.7-1.8-1.2
Intermittent access day 1 locomotion2.42.42.71.6-1.6-1.61.51.6-1.6-1.4
Intermittent access day 15 total locomotion1.01.01.31.1-0.9-1.01.11.1-1.0-0.9
Intermittent access total locomotion0.70.81.61.1-0.9-0.80.91.3-0.8-0.4
Intermittent access standard deviation0.30.30.50.6-0.7-0.60.50.7-0.6-0.4
Cocaine induced anxiety0.30.40.80.5-0.5-0.70.70.1-0.7-0.9
Post-drug Anxiety1.21.31.9-1.31.31.1-1.2-1.41.00.6
Baseline Anxiety1.81.92.3-1.41.41.4-1.5-1.11.41.3
Lifetime Intake4.85.38.32.6-2.4-2.22.12.9-2.2-1.5
Incentive Sensitization - Responses0.20.21.00.3-0.20.1-0.21.00.00.5
Incentive Sensitization - Breakpoint0.20.20.60.10.00.2-0.40.70.20.6
Progressive ratio test 1 active lever presses2.72.84.41.9-1.8-1.61.52.1-1.5-1.1
Progressive ratio test 1 breakpoint2.32.33.41.7-1.6-1.51.41.8-1.4-1.0
Progressive ratio test 1 inactive lever presses6.06.47.62.7-2.7-2.52.42.8-2.5-2.0
Progressive ratio test 2 active lever presses0.70.82.81.0-0.9-0.60.51.7-0.60.1
Progressive ratio test 2 breakpoint0.80.92.91.1-1.0-0.60.61.7-0.6-0.0
Progressive ratio test 2 inactive lever presses3.03.54.22.0-1.9-1.91.72.0-1.9-1.6
Total sessions with >9 infusions4.55.08.62.6-2.5-2.12.02.9-2.0-1.2
Short access day 1 total inactive lever presses5.05.56.22.4-2.3-2.42.22.2-2.5-2.4
Short access day 10 total inactive lever presses0.70.82.20.4-0.6-1.00.9-0.4-1.0-1.5
Short access day 1 total infusions6.46.87.92.8-2.7-2.62.62.6-2.6-2.2
Short access day 10 total infusions5.56.08.82.7-2.6-2.42.33.0-2.4-1.7
Short access total infusions4.75.27.72.6-2.4-2.22.12.8-2.1-1.5
Short access day 1 locomotion8.28.710.23.2-3.1-3.03.02.9-2.9-2.5
Short access day 10 total locomotion1.01.11.41.1-1.1-1.00.91.2-1.1-0.8
Short access total locomotion1.41.43.11.4-1.3-1.10.91.8-1.1-0.5
Compulsive drug intake1.71.64.2-1.51.41.0-1.0-2.01.00.3
One hour access (0.3 mA shock)2.22.53.11.8-1.6-1.61.61.7-1.6-1.3
One hour access (shock baseline)3.74.28.32.4-2.2-1.81.92.9-1.8-1.0
Number of responses in last shaping day1.31.32.81.4-1.2-1.01.01.7-1.0-0.4
Context. condit. distance diff. score0.00.00.20.2-0.10.0-0.10.40.00.3
Locomotion velocity, session 10.30.31.2-0.60.60.3-0.1-1.10.2-0.3
Locomotion distance, session 11.11.53.10.9-0.9-1.21.50.1-1.3-1.8
Locomotion velocity, session 20.20.30.3-0.50.50.6-0.5-0.40.50.6
Locomotion distance, session 20.10.10.6-0.30.30.10.1-0.80.1-0.3
Locomotion velocity, session 30.50.61.10.5-0.8-0.90.70.1-0.9-1.0
Locomotion distance, session 30.60.61.80.3-0.5-0.80.9-0.4-0.8-1.4
Stereotopy head waving bouts, day 32.22.63.11.7-1.8-1.61.61.6-1.6-1.3
Stereotopy head waving duration, day 30.30.40.90.8-0.7-0.60.50.9-0.5-0.2
Locomotion velocity, session 70.80.92.10.7-0.7-1.01.1-0.0-1.0-1.4
Locomotion distance, session 70.20.31.2-0.30.4-0.00.4-1.1-0.0-0.8
Stereotopy head waving bouts, day 70.00.00.0-0.10.10.1-0.2-0.00.10.2
Stereotopy head waving duration, day 70.40.50.70.8-0.8-0.70.70.7-0.7-0.5
Locomotion velocity, session 80.40.50.70.9-0.7-0.60.80.8-0.6-0.4
Locomotion distance, session 80.20.30.50.7-0.5-0.60.70.4-0.6-0.6
Degree of sensitization distance0.70.71.0-0.81.00.9-0.8-0.70.90.8
Degree of sensitization stereotypy0.30.30.4-0.60.50.5-0.5-0.60.50.5
Condit. Reinf. active minus inactive responses1.01.11.9-1.21.21.0-1.0-1.41.00.5
Condit. Reinf. active-inactive response ratio0.91.01.2-1.11.00.9-1.1-1.11.00.7
Condit. Reinf. active responses0.10.10.30.00.1-0.20.3-0.3-0.2-0.6
Condit. Reinf. inactive responses1.31.52.11.3-1.1-1.21.50.8-1.3-1.4
Incentive salience index mean0.00.10.2-0.20.20.1-0.0-0.50.0-0.3
Condit. Reinf. lever presses0.40.50.60.7-0.7-0.70.70.7-0.7-0.7
Time in familiar zone, hab. session 10.70.70.9-0.81.00.9-0.7-0.90.80.6
Time in novel zone, hab. session 10.40.40.7-0.70.40.6-0.8-0.40.70.9
Total zone transitions, hab. session 10.10.10.20.4-0.2-0.30.50.3-0.3-0.3
Total locomotion distance, hab. session 10.30.51.00.9-0.7-0.50.71.0-0.6-0.2
Locomotion velocity, hab. session 11.11.62.11.4-1.2-1.21.31.5-1.2-0.9
Time in familiar zone, hab. session 20.10.10.2-0.10.20.00.2-0.50.0-0.4
Time in novel zone, hab. session 20.40.40.9-0.50.40.6-0.8-0.10.60.9
Total zone transitions, hab. session 20.20.20.8-0.20.3-0.00.5-0.9-0.1-0.6
Total locomotion distance, hab. session 20.20.20.60.10.1-0.30.7-0.6-0.3-0.8
Locomotion velocity, hab. session 20.30.41.00.3-0.2-0.50.9-0.4-0.5-1.0
Novel to familiar place preference ratio1.11.21.4-1.11.01.1-1.2-0.91.11.2
Novelty place preference1.71.82.1-1.41.21.4-1.4-1.11.41.4
Time in novel zone, NPP test1.91.92.4-1.51.31.4-1.6-1.11.41.5
Total zone transitions, NPP test1.11.52.11.1-1.2-1.31.40.6-1.3-1.5
Total locomotion distance, NPP test1.62.32.81.4-1.5-1.61.71.0-1.6-1.7
Locomotion velocity, NPP test2.63.84.81.9-1.8-2.02.21.2-2.1-2.2
Pavlov. Cond. lever latency1.21.62.8-1.11.11.3-1.4-0.61.41.7
Pavlov. Cond. magazine entry latency0.00.00.1-0.00.1-0.10.1-0.3-0.1-0.3
Pavlov. Cond. change in total contacts0.00.00.00.1-0.1-0.10.1-0.0-0.1-0.2
Pavlov. Cond. index score0.40.61.40.5-0.5-0.80.90.0-0.8-1.2
Pavlov. Cond. latency score0.40.51.50.4-0.4-0.70.8-0.2-0.8-1.2
Pavlov. Cond. lever contacts0.70.81.40.9-0.8-1.01.00.5-1.0-1.2
Pavlov. Cond. magazine entry number0.30.41.0-0.40.40.6-0.70.10.61.0
Pavlov. Cond. intertrial magazine entries1.51.83.01.5-1.5-1.31.11.7-1.3-0.8
Pavlov. Cond. lever-magazine prob. diff.1.11.32.41.0-1.0-1.21.30.5-1.2-1.5
Pavlov. Cond. response bias1.21.51.81.2-1.2-1.31.21.0-1.3-1.3
Bone: apparent density4.67.69.02.8-2.6-2.83.02.2-2.9-2.9
Bone surface2.03.55.91.7-1.5-1.92.30.8-2.0-2.4
Bone volume2.44.05.22.0-1.8-2.02.31.5-2.1-2.2
Bone: connectivity density4.06.38.62.4-2.3-2.62.81.6-2.7-2.9
Bone: cortical apparent density0.20.30.40.6-0.4-0.50.60.3-0.5-0.6
Bone: cortical area0.20.30.90.1-0.0-0.40.7-0.7-0.4-1.0
Bone: cortical porosity2.12.33.11.6-1.8-1.51.41.7-1.5-0.9
Bone: cortical porosity1.71.82.41.4-1.5-1.41.21.6-1.4-0.9
Bone: cortical thickness0.20.30.8-0.60.70.4-0.2-0.90.40.1
Bone: cortical thickness1.11.32.01.1-1.0-1.21.30.6-1.2-1.4
Bone: cortical tissue density0.10.20.30.5-0.3-0.40.50.2-0.4-0.5
Bone: elastic displacement1.21.32.41.3-1.3-1.10.91.6-1.1-0.6
Bone: elastic work0.91.21.31.1-1.1-1.11.10.8-1.1-1.1
Bone: endosteal estimation0.30.71.50.7-0.6-0.81.10.2-0.8-1.2
Bone: endosteal perimeter0.10.20.60.3-0.2-0.40.6-0.2-0.4-0.8
Bone: final force0.10.10.40.2-0.0-0.30.6-0.4-0.3-0.6
Bone: final moment0.10.20.40.3-0.1-0.30.7-0.3-0.3-0.7
Bone: marrow area0.40.81.50.8-0.6-0.91.10.2-0.9-1.2
Bone: maximum diameter0.51.02.70.6-0.5-1.01.3-0.3-1.0-1.6
Bone: maximum force0.00.10.2-0.00.1-0.10.3-0.4-0.1-0.3
Bone: maximum moment0.00.10.20.10.0-0.20.4-0.3-0.2-0.4
Bone: minimum diameter0.30.62.0-0.80.80.5-0.1-1.40.5-0.0
Bone: periosteal estimation0.40.81.90.7-0.6-0.91.20.0-0.9-1.4
Bone: periosteal perimeter0.10.20.60.2-0.0-0.30.6-0.4-0.3-0.8
Bone: post-yield work0.81.12.21.2-1.1-0.91.01.5-1.0-0.5
Bone: stiffness0.10.10.6-0.40.40.20.0-0.80.2-0.1
Bone: tissue strength0.90.81.3-0.90.81.0-1.0-0.51.01.1
Bone: trabecular number3.85.96.52.5-2.3-2.42.62.2-2.5-2.5
Bone: trabecular spacing3.03.95.6-2.01.72.0-2.4-1.22.02.3
Bone: trabecular thickness0.81.01.71.1-0.9-1.01.30.8-1.0-1.0
Bone: trabecular tissue density0.30.40.50.7-0.6-0.60.50.7-0.6-0.4
Breakpoint value in progressive ratio session1.31.42.01.3-1.2-1.21.41.0-1.1-1.0
Distance traveled before self-admin0.10.10.50.4-0.2-0.10.10.7-0.10.2
Distance traveled after self-admin0.80.81.0-0.91.01.0-1.0-0.51.01.0
Delta time in closed arm before/after self-admin0.20.20.9-0.50.50.3-0.2-0.90.3-0.1
Delta time in open arm before/after self-admin0.30.30.40.4-0.6-0.60.60.3-0.6-0.7
Diff in mean of infusions in LGA sessions0.20.20.50.5-0.4-0.50.70.2-0.5-0.6
Extinction: sum of active levers before priming0.30.30.40.5-0.5-0.50.60.4-0.6-0.6
Active lever presses in extinction session 61.21.11.61.2-1.2-0.91.11.3-0.9-0.5
Delta distance traveled before/after self-admin1.61.72.4-1.51.41.3-1.3-1.51.20.8
Delta ambulatory time before/after self-admin0.40.40.8-0.70.70.5-0.5-0.90.50.2
Time in closed arm before self-admin0.30.30.5-0.40.60.6-0.4-0.30.70.7
Time in closed arm after self-admin1.01.01.4-0.91.01.1-0.9-0.71.21.2
Time in open arm before self-admin0.10.10.2-0.40.30.2-0.4-0.40.10.0
Time in open arm after self-admin1.21.32.50.9-1.0-1.31.00.5-1.3-1.6
Sum of active levers in priming session hrs 5-60.50.41.60.1-0.1-0.60.6-0.7-0.6-1.3
Time to tail flick, vehicle, before self-admin1.81.82.8-1.21.21.4-1.5-0.61.51.7
Time to tail flick, vehicle, after self-admin3.73.94.7-1.92.12.1-1.8-1.82.22.0
Time to tail flick, test, before self-admin0.90.91.71.1-1.0-0.80.81.3-0.8-0.5
Time to tail flick, test, after self-admin0.20.20.90.3-0.20.1-0.20.90.10.7
Delta time to tail flick, vehicle, before/after SA0.30.21.2-0.40.40.20.1-1.10.2-0.2
Delta time to tail flick, test, before/after SA0.50.51.10.8-0.7-0.60.51.1-0.6-0.3
Ambulatory time before self-admin0.10.10.40.4-0.3-0.30.30.6-0.3-0.1
Ambulatory time after self-admin0.50.50.8-0.70.70.8-0.9-0.30.70.8
Total heroin consumption2.32.83.41.7-1.6-1.71.81.3-1.7-1.8
Area under the delay curve0.00.00.00.00.20.10.2-0.10.10.0
Delay disc. indifference point, 0s delay3.23.44.3-1.71.92.0-1.8-1.22.02.1
Delay disc. indifference point, 16s delay0.10.10.10.0-0.0-0.20.3-0.3-0.2-0.4
Delay disc. indifference point, 2s delay0.30.30.4-0.60.60.6-0.5-0.50.60.6
Delay disc. indifference point, 24s delay1.21.22.31.3-1.1-0.91.01.5-0.9-0.4
Delay disc. indifference point, 4s delay0.00.00.1-0.10.30.10.1-0.40.1-0.2
Delay disc. indifference point, 8s delay0.00.00.10.3-0.1-0.10.30.3-0.10.0
Delay discount exponential model param0.10.10.2-0.30.10.2-0.4-0.10.20.2
Delay discount hyperbolic model param0.10.10.2-0.30.10.2-0.5-0.00.20.3
Fecal boli incidents, locomotor time 10.70.82.61.0-1.0-0.70.41.6-0.7-0.1
Change in fecal boli incidents, locomotor task4.34.14.6-2.02.12.1-2.0-1.82.11.9
Time >=10cm from walls, locomotor time 10.20.20.50.3-0.00.2-0.20.70.20.7
Bouts of movement, locomotor time 11.71.83.71.1-1.0-1.41.8-0.0-1.4-1.9
Total resting periods, locomotor time 11.92.24.31.1-1.1-1.51.90.0-1.5-2.1
Rest time, locomotor task time 10.10.10.20.2-0.4-0.30.40.1-0.3-0.3
Distance moved, locomotor task time 11.01.11.8-0.91.01.1-1.3-0.41.11.3
Vertical activity count, locomotor time 10.60.60.8-0.70.80.8-0.9-0.40.80.9
Time >=10cm from walls, locomotor time 20.70.71.81.1-0.8-0.60.61.3-0.6-0.0
Bouts of movement, locomotor time 20.30.30.7-0.50.70.5-0.2-0.80.50.2
Total resting periods, locomotor time 20.20.20.8-0.40.50.20.1-0.90.2-0.3
Rest time, locomotor task time 20.91.12.40.7-0.8-1.11.3-0.1-1.1-1.6
Distance moved, locomotor task time 20.50.61.8-0.40.50.8-0.90.30.81.3
Vertical activity count, locomotor time 20.30.31.00.10.10.4-0.50.60.41.0
Weight adjusted by age0.10.10.5-0.20.1-0.10.2-0.7-0.0-0.3
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.2-0.0-0.10.0-0.3-0.1-0.2
Locomotion in novel chamber0.60.81.0-0.80.80.9-1.0-0.51.01.0
Locomotion in novel chamber post-restriction2.73.24.8-2.01.81.7-1.6-2.21.81.3
Progressive ratio0.10.10.30.4-0.4-0.40.50.3-0.3-0.2
Food seeking constrained by brief footshock6.78.113.13.2-3.2-2.72.43.6-2.7-1.6
Seeking ratio, punishment vs. effort0.50.71.50.9-0.9-0.80.51.2-0.8-0.4
Run reversals in cocaine runway, females0.30.30.70.0-0.10.2-0.50.80.20.8
Run reversals in cocaine runway, males0.40.31.10.6-0.7-0.40.21.1-0.40.1
Latency to leave start box in cocaine runway0.70.81.11.0-0.9-0.90.81.0-0.9-0.7
Latency to leave start box in cocaine runway, F0.50.50.70.7-0.6-0.70.70.6-0.7-0.8
Latency to leave start box in cocaine runway, M1.41.42.61.3-1.3-1.10.91.6-1.1-0.6
Cd content in liver0.10.10.5-0.20.40.10.1-0.70.1-0.3
Co content in liver5.36.37.22.7-2.6-2.52.52.5-2.5-2.2
Cu content in liver0.00.10.10.3-0.2-0.20.30.2-0.2-0.2
Fe content in liver0.00.00.0-0.1-0.2-0.1-0.0-0.1-0.1-0.0
K content in liver0.70.72.4-0.81.00.5-0.2-1.60.5-0.3
Mg content in liver0.90.93.0-1.01.20.7-0.3-1.70.7-0.1
Mn content in liver0.50.61.70.2-0.3-0.70.8-0.7-0.6-1.3
Na content in liver0.70.71.20.9-0.9-0.80.81.1-0.8-0.6
Rb content in liver0.20.20.7-0.40.50.2-0.0-0.90.2-0.3
Se content in liver0.50.61.7-0.80.90.6-0.4-1.30.70.1
Sr content in liver0.10.10.2-0.20.40.4-0.40.00.40.5
Zn content in liver1.51.72.3-1.31.51.3-1.0-1.51.41.0