Hub : Genes

Nudt15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000025239 0.03 0.02 3.2e-03 0.01 0.01 0.02 0.01 2.4e-02 1.2e-02 5.0e-03 1.1e-02
2 Adipose intron excision ratio chr15:48711928:48713567 0.03 0.02 6.1e-03 0.02 0 0.01 0.01 6.5e-03 1.0e-01 2.0e-02 4.3e-02
3 BLA gene expression ENSRNOG00000025239 0.07 0.05 2.4e-03 0.04 0.01 0.01 0.02 2.2e-03 6.4e-02 7.2e-02 2.0e-02
4 BLA intron excision ratio chr15:48711928:48713263 0.1 0.06 7.2e-04 0.04 0.06 0.09 0.05 2.7e-03 2.6e-04 1.5e-05 9.7e-04
5 BLA intron excision ratio chr15:48711928:48713567 0.09 0.06 1.1e-03 0.06 0.06 0.09 0.05 5.5e-04 3.7e-04 2.2e-05 1.1e-03
6 Brain gene expression ENSRNOG00000025239 0.12 0.06 8.5e-11 0.14 0.12 0.12 0.13 1.7e-12 4.5e-11 1.9e-11 3.1e-12
7 Brain intron excision ratio chr15:48711928:48713567 0.14 0.07 4.3e-09 0.09 0.09 0.09 0.09 1.8e-08 4.5e-09 1.5e-08 1.5e-08
8 IL gene expression ENSRNOG00000025239 0.18 0.1 2.1e-03 0.05 0.09 0.04 0.05 2.7e-02 3.9e-03 4.5e-02 2.4e-02
9 Liver intron excision ratio chr15:48711928:48713567 0.07 0.04 5.3e-08 0.05 0.06 0.06 0.06 5.6e-06 3.7e-07 7.7e-07 1.0e-06
10 NAcc gene expression ENSRNOG00000025239 0.12 0.06 1.9e-07 0.06 0.09 0.09 0.09 6.1e-05 3.5e-07 4.6e-07 4.3e-07
11 NAcc intron excision ratio chr15:48711928:48713567 0.05 0.03 3.0e-03 0.03 0.04 0.03 0.03 2.1e-03 1.1e-03 4.1e-03 2.1e-03
12 PL gene expression ENSRNOG00000025239 0.05 0.03 5.3e-04 0.03 0.02 0.02 0.02 1.5e-03 8.2e-03 6.8e-03 9.4e-03
13 PL intron excision ratio chr15:48711928:48713567 0.24 0.14 5.4e-10 0.14 0.13 0.13 0.13 1.3e-10 5.9e-10 2.9e-10 3.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.10.20.50.30.50.50.2-0.20.40.30.70.40.70.60.50.1
BMI without tail0.51.02.90.7-0.41.3-0.00.11.20.11.6-0.11.70.71.7-0.3
Body weight0.72.86.62.0-1.41.22.5-2.61.0-2.20.3-2.00.0-1.31.0-2.0
Epididymis fat weight1.12.76.11.5-2.12.00.8-0.71.9-1.11.6-1.91.7-0.22.5-1.7
Glucose0.71.12.9-0.81.60.5-1.21.20.31.30.81.70.91.30.00.8
Heart weight0.10.10.4-0.7-0.5-0.2-0.50.6-0.10.1-0.2-0.1-0.1-0.30.1-0.2
Left kidney weight1.44.09.31.7-3.11.52.2-2.21.3-2.40.4-2.70.4-2.01.7-2.5
Right kidney weight2.77.620.22.4-4.51.43.2-3.11.3-3.40.2-3.90.2-3.01.9-3.2
Tail length0.92.95.51.6-2.41.51.9-1.81.4-1.90.6-2.10.5-1.51.7-2.1
Length with tail0.72.65.51.6-1.70.52.3-2.30.3-2.3-0.4-2.2-0.7-1.70.3-1.8
Length without tail0.61.23.00.00.1-1.21.1-1.2-1.3-0.8-1.5-0.5-1.7-1.0-1.7-0.1
Liver weight, left0.10.20.6-0.80.4-0.4-0.30.3-0.50.1-0.70.0-0.8-0.1-0.70.1
Liver weight, right0.10.10.9-0.10.90.10.4-0.4-0.0-0.0-0.20.5-0.4-0.0-0.50.0
Parametrial fat weight0.71.33.80.5-0.21.4-0.60.61.20.71.9-0.12.01.41.6-0.2
Retroperitoneal fat weight0.30.91.90.9-0.71.20.1-0.21.3-0.11.4-0.81.40.71.3-0.7
Intraocular pressure0.70.92.50.7-0.61.60.2-0.21.6-0.70.9-0.90.80.11.2-1.4
Extensor digitorum longus weight3.714.928.1-4.14.2-5.2-1.71.7-5.12.4-4.23.9-4.10.1-5.34.1
Soleus weight3.19.014.6-3.23.7-3.6-2.12.1-3.62.6-2.43.4-2.41.1-3.83.6
Tibialis anterior weight2.17.317.7-2.42.8-3.7-0.50.5-3.71.2-3.22.5-3.3-0.5-4.22.6
Tibia length6.618.532.34.6-5.43.45.0-4.93.3-5.40.9-5.50.5-3.93.3-5.7
Number of licking bursts0.91.12.81.3-0.11.60.6-0.61.7-0.61.3-0.61.20.51.2-0.9
Food consumed during 24 hour testing period0.20.31.1-0.4-0.90.20.5-0.40.2-0.6-0.5-0.4-0.4-1.10.0-0.7
Times rat made contact with spout2.32.66.21.7-0.92.50.9-0.92.4-1.02.0-1.11.80.22.2-1.7
Mean time between licks in bursts0.10.10.4-0.4-0.30.3-0.40.40.20.30.30.00.40.10.60.0
Mean num. licks in bursts0.00.00.10.0-0.20.20.2-0.20.1-0.10.1-0.00.1-0.30.3-0.3
Std. dev. time between licks in bursts1.01.24.90.0-2.20.40.6-0.50.3-1.2-0.6-1.6-0.4-1.60.9-1.4
Water consumed over 24 hours0.10.20.4-0.4-0.20.30.6-0.60.2-0.5-0.2-0.2-0.3-0.6-0.1-0.5
Indifference point 0 sec4.16.612.62.8-3.12.52.5-2.52.5-3.10.7-3.30.4-2.22.2-3.5
Indifference point AUC2.02.34.9-1.91.7-0.9-2.02.1-0.82.1-0.22.20.01.2-1.01.5
Indifference point function ln k2.13.05.82.3-2.00.92.4-2.40.9-2.30.4-2.40.1-1.41.1-1.7
Indifference point function log k2.13.05.82.3-2.00.92.4-2.40.9-2.30.4-2.40.1-1.41.1-1.7
Delay discounting total patch changes 0 sec4.06.512.72.8-3.02.42.6-2.62.5-3.20.6-3.20.3-2.22.2-3.6
Delay discounting total patch changes 12 sec0.81.13.30.7-1.21.10.9-0.80.9-1.3-0.2-1.1-0.3-1.30.6-1.8
Delay discounting total patch changes 18 sec0.60.82.21.1-0.21.50.2-0.21.4-0.61.0-0.60.90.21.2-1.1
Delay discounting total patch changes 24 sec1.51.94.21.3-1.41.31.4-1.41.4-1.80.0-1.6-0.1-1.51.1-2.0
Delay discounting total patch changes 6 sec1.62.46.01.9-1.02.30.6-0.62.5-1.01.8-1.31.60.32.0-1.7
Delay discounting time to switch 0 sec0.00.10.30.0-0.1-0.40.1-0.1-0.5-0.2-0.3-0.3-0.3-0.3-0.10.0
Delay discounting water rate 0 sec1.01.62.91.5-0.81.41.7-1.71.4-1.60.5-1.30.3-0.81.0-1.6
Delay discounting water rate 12 sec0.00.10.20.4-0.0-0.00.2-0.30.1-0.20.2-0.50.10.20.00.1
Delay discounting water rate 18 sec0.10.20.50.50.40.30.0-0.00.30.20.70.10.60.70.20.3
Delay discounting water rate 24 sec0.81.12.81.30.61.50.1-0.21.6-0.21.7-0.31.41.21.1-0.4
Delay discounting water rate 6 sec0.20.30.70.30.5-0.40.8-0.8-0.4-0.6-0.6-0.0-0.8-0.4-0.50.1
Locomotor activity3.75.814.5-0.8-1.0-2.32.2-2.2-2.3-2.1-3.7-1.0-3.8-3.6-2.5-0.9
Locomotor testing distance2.94.811.80.4-1.6-1.22.6-2.6-1.0-2.8-2.6-1.9-2.9-3.4-1.3-1.8
Locomotor testing rearing3.45.413.90.5-2.1-1.02.7-2.6-0.7-3.1-2.6-2.3-2.8-3.7-0.9-2.3
Light reinforcement 11.52.75.91.8-0.92.40.2-0.22.3-0.52.4-1.02.30.82.3-1.2
Light reinforcement 21.82.47.00.60.71.4-1.01.01.31.42.60.72.62.41.50.7
Reaction time number correct1.72.44.6-1.32.2-0.7-1.91.9-0.52.00.22.00.31.9-1.02.0
Reaction time mean minus median1.31.74.20.0-1.0-0.71.4-1.4-0.6-1.5-1.8-1.2-1.9-2.0-0.9-1.1
Reaction time mean minus median AUC0.50.61.70.1-0.7-0.20.9-0.9-0.0-0.9-1.0-0.7-1.0-1.3-0.4-0.9
Reaction time num false alarms0.10.10.6-0.8-0.4-0.0-0.40.50.20.3-0.10.30.0-0.2-0.1-0.2
Reaction time num false alarms AUC0.10.10.5-0.7-0.50.2-0.50.50.30.40.10.30.3-0.10.2-0.2
Reaction time trials correct on left1.72.44.6-1.32.2-0.7-1.91.9-0.52.00.22.00.31.9-1.02.0
Reaction time trials on left1.62.34.4-1.32.1-0.6-1.91.9-0.52.00.32.00.41.9-0.91.9
Reaction time mean0.91.22.8-0.5-1.0-1.30.8-0.8-1.3-0.8-1.7-0.7-1.6-1.7-1.0-0.3
Reaction time mean AUC1.21.63.9-0.7-0.9-1.50.8-0.8-1.6-0.8-2.0-0.6-1.9-1.8-1.2-0.2
Median of all reaction times0.60.81.8-0.6-0.9-1.20.4-0.4-1.3-0.3-1.3-0.3-1.2-1.2-0.70.1
Reaction time omissions0.20.31.00.2-1.00.40.2-0.20.5-0.6-0.0-0.90.0-0.50.5-1.0
Reaction time false alarm rate0.40.51.80.2-1.30.70.5-0.40.8-0.60.2-0.70.3-0.80.7-1.2
Reaction time premature initiation rate0.50.72.30.10.8-0.2-1.11.1-0.40.90.70.30.71.5-0.11.2
Reaction time premature initiations1.72.56.0-0.71.9-0.6-2.12.0-0.72.00.81.40.92.5-0.62.2
Std. dev. reaction times0.81.13.0-0.5-0.7-1.00.7-0.7-0.9-0.9-1.7-0.7-1.7-1.6-1.0-0.6
Reaction time trials completed1.62.34.4-1.32.1-0.6-1.91.9-0.52.00.32.00.41.9-0.91.9
Reaction time trials AUC1.72.44.6-1.42.2-0.7-1.91.9-0.52.10.22.10.31.9-1.02.0
Social response proportion3.63.98.0-1.81.9-0.8-2.82.8-0.82.70.72.11.02.5-0.72.4
Social responses1.11.54.5-1.10.3-0.1-2.12.1-0.21.70.80.81.11.50.11.1
Social time0.30.31.3-0.0-1.1-0.10.3-0.2-0.3-0.6-0.5-0.8-0.4-1.00.2-0.7
Conditioned locomotion0.30.41.0-0.20.5-0.2-0.60.6-0.30.80.60.50.71.0-0.10.9
Cocaine response after cond. corrected2.22.55.1-1.42.0-1.0-1.81.8-0.82.20.31.90.42.0-1.02.2
Cocaine response after cond. not corrected0.80.91.8-0.91.1-0.4-1.11.1-0.31.30.31.20.41.2-0.31.3
Cocaine response before conditioning2.73.37.11.6-2.31.51.9-1.91.4-2.30.1-2.10.0-2.01.6-2.7
Saline control response1.31.73.41.8-0.61.31.8-1.81.1-1.70.4-1.40.1-0.81.0-1.7
Condit. Reinf. active minus inactive responses0.30.30.70.4-0.60.9-0.10.10.8-0.30.6-0.70.60.10.7-0.7
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.10.4-0.50.50.40.40.30.30.40.30.4-0.1
Condit. Reinf. active responses0.50.71.70.7-0.91.30.2-0.21.3-0.60.8-0.90.8-0.11.0-1.2
Condit. Reinf. inactive responses1.21.52.91.3-1.11.61.0-1.01.5-1.30.9-1.40.7-0.51.2-1.7
Condit. Reinf. lever presses1.62.24.90.9-2.20.71.6-1.50.6-1.9-0.4-1.9-0.5-2.00.7-2.0
Condit. Reinf. lever reinforcers received0.71.02.20.9-1.11.40.6-0.61.3-0.80.7-1.10.7-0.41.2-1.5
Pavlov. Cond. lever latency1.11.53.8-0.31.50.1-1.61.50.21.51.11.21.12.00.21.3
Pavlov. Cond. magazine entry latency1.72.05.00.9-1.60.12.2-2.2-0.1-1.8-0.8-1.3-0.9-2.10.1-1.5
Pavlov. Cond. change in total contacts1.01.53.7-1.0-0.1-1.70.5-0.5-1.6-0.2-1.90.2-1.8-1.3-1.70.4
Pavlov. Cond. index score1.62.15.50.4-1.4-0.62.1-2.0-0.7-1.7-1.5-1.1-1.6-2.3-0.6-1.2
Pavlov. Cond. latency score1.82.35.70.4-1.6-0.62.1-2.0-0.7-1.7-1.5-1.3-1.6-2.4-0.6-1.2
Pavlov. Cond. lever contacts1.72.36.50.2-1.7-0.41.9-1.9-0.4-1.9-1.6-1.4-1.6-2.5-0.5-1.6
Pavlov. Cond. magazine entry number1.01.22.9-0.71.5-0.2-1.71.7-0.11.30.51.00.51.6-0.21.2
Pavlov. Cond. intertrial magazine entries2.63.38.21.4-1.42.80.2-0.12.9-0.82.3-1.32.30.52.6-1.8
Pavlov. Cond. lever-magazine prob. diff.1.31.64.40.2-1.3-0.71.7-1.7-0.8-1.4-1.5-0.9-1.5-2.1-0.7-1.0
Pavlov. Cond. response bias2.02.77.60.3-1.6-0.42.2-2.2-0.4-2.0-1.8-1.3-1.8-2.8-0.6-1.7
Conditioned reinforcement - actives1.61.63.7-0.71.10.3-1.71.70.01.81.11.41.31.90.11.3
Conditioned reinforcement - inactives1.41.62.51.5-1.51.61.1-1.11.4-1.20.9-1.40.8-0.61.4-1.4
Conditioned locomotion0.10.10.3-0.6-0.3-0.0-0.30.3-0.30.2-0.20.3-0.0-0.2-0.30.1
Intermittent access intake day 1-15 change2.22.24.52.1-1.21.71.2-1.21.8-1.31.5-1.71.3-0.01.8-1.4
Intermittent access intake escalation1.91.94.22.0-0.81.61.1-1.11.7-1.21.5-1.41.20.11.7-1.3
Intermittent access intake escalation 20.30.30.70.6-0.40.60.2-0.20.6-0.20.9-0.60.80.40.8-0.2
Intermitt. access day 1 inactive lever presses0.80.91.81.3-0.71.30.6-0.61.1-1.00.9-1.30.70.11.0-1.0
Intermitt. access day 15 inactive lever presses1.11.22.31.3-1.11.21.0-1.01.0-1.40.5-1.50.3-0.71.0-1.3
Intermitt. access escalation Index0.20.20.7-0.20.9-0.6-0.00.0-0.40.1-0.50.5-0.6-0.0-0.70.3
Intermittent access day 1 total infusions1.31.53.31.5-0.51.81.3-1.31.7-1.30.9-0.90.7-0.41.2-1.6
Intermittent access day 15 total infusions2.22.54.72.1-0.82.21.3-1.32.1-1.41.6-1.41.3-0.01.8-1.7
Intermittent access terminal intake (last 3 days)1.11.22.71.5-0.41.70.7-0.81.5-0.81.3-0.81.10.21.3-1.1
Intermittent access total infusions2.32.55.22.2-0.72.31.3-1.32.2-1.31.7-1.21.40.01.8-1.7
Intermittent access day 1 locomotion2.72.84.62.0-1.42.11.6-1.62.1-1.81.1-1.70.8-0.81.6-2.1
Intermittent access day 15 total locomotion0.90.92.70.9-0.41.60.0-0.11.3-0.31.4-0.51.30.51.4-0.7
Intermittent access total locomotion1.82.13.91.7-1.12.01.3-1.31.8-1.51.1-1.40.9-0.51.6-1.8
Intermittent access standard deviation1.01.02.21.5-0.11.41.1-1.21.2-1.20.6-1.00.3-0.30.9-1.2
Cocaine induced anxiety1.92.25.5-0.8-0.9-1.71.0-0.9-1.7-1.1-2.3-0.6-2.3-2.1-1.5-0.3
Post-drug Anxiety0.30.31.30.5-1.2-0.10.3-0.3-0.1-0.6-0.1-1.1-0.1-0.40.3-0.4
Baseline Anxiety1.81.94.01.7-0.62.00.4-0.51.9-0.42.0-1.01.90.81.9-1.0
Lifetime Intake1.82.04.22.0-0.62.11.3-1.32.0-1.31.4-1.11.1-0.21.5-1.6
Incentive Sensitization - Responses1.11.12.91.0-0.41.6-0.20.21.40.21.6-0.11.70.71.5-0.5
Incentive Sensitization - Breakpoint1.41.43.21.2-0.71.8-0.00.11.6-0.01.7-0.31.80.61.7-0.7
Progressive ratio test 1 active lever presses0.60.61.90.60.61.40.0-0.01.20.11.20.21.00.80.7-0.4
Progressive ratio test 1 breakpoint0.70.81.90.50.71.4-0.20.21.20.31.40.41.21.10.8-0.2
Progressive ratio test 1 inactive lever presses3.53.88.72.6-0.63.01.0-1.12.8-1.32.4-1.62.10.72.4-1.8
Progressive ratio test 2 active lever presses1.71.84.60.90.52.0-0.50.51.80.52.10.42.11.51.6-0.3
Progressive ratio test 2 breakpoint1.71.94.91.30.02.2-0.10.02.00.02.1-0.12.01.11.8-0.7
Progressive ratio test 2 inactive lever presses1.51.73.91.5-0.82.00.9-0.91.8-1.11.4-1.11.2-0.01.6-1.5
Total sessions with >9 infusions0.20.30.60.5-0.40.80.0-0.00.7-0.00.8-0.20.80.30.6-0.3
Short access day 1 total inactive lever presses3.84.37.62.7-1.32.82.1-2.12.6-2.31.3-1.91.0-1.02.1-2.7
Short access day 10 total inactive lever presses0.80.91.81.3-0.51.30.5-0.51.3-0.71.1-1.01.00.31.2-0.9
Short access day 1 total infusions0.30.30.90.60.20.90.1-0.10.9-0.10.8-0.00.70.40.4-0.5
Short access day 10 total infusions1.82.04.41.5-0.81.32.1-2.11.1-1.9-0.1-1.2-0.4-1.50.5-1.8
Short access total infusions1.61.83.51.8-0.71.91.3-1.31.8-1.41.1-1.10.9-0.41.3-1.6
Short access day 1 locomotion0.60.71.70.2-0.9-0.31.0-1.0-0.2-1.1-0.8-0.9-0.9-1.3-0.5-0.8
Short access day 10 total locomotion0.60.62.10.4-1.40.21.0-1.00.2-0.9-0.2-0.9-0.2-1.10.4-0.8
Short access total locomotion1.61.73.61.2-1.91.01.4-1.41.0-1.60.2-1.80.2-1.20.8-1.6
Compulsive drug intake1.21.22.81.1-0.80.21.7-1.70.3-1.6-0.6-1.2-0.8-1.40.1-1.2
One hour access (0.3 mA shock)0.70.91.71.3-0.11.21.2-1.31.2-1.10.6-0.60.3-0.30.7-1.1
One hour access (shock baseline)0.20.20.9-0.20.90.3-0.30.30.30.40.40.70.30.7-0.20.3
Number of responses in last shaping day0.10.10.3-0.50.3-0.6-0.30.3-0.50.3-0.40.4-0.4-0.1-0.40.3
Context. condit. distance diff. score2.42.98.11.10.91.7-1.01.01.61.22.80.82.82.51.80.8
Locomotion velocity, session 11.11.22.7-1.20.6-1.5-0.20.2-1.60.3-1.60.7-1.5-0.6-1.40.8
Locomotion distance, session 10.50.72.1-0.0-0.6-0.10.9-0.9-0.2-0.9-1.1-0.5-1.2-1.5-0.3-0.9
Locomotion velocity, session 20.30.31.0-0.7-0.5-0.20.1-0.1-0.2-0.5-1.0-0.3-1.0-1.0-0.3-0.6
Locomotion distance, session 21.52.16.4-0.2-0.8-0.41.6-1.6-0.4-1.7-2.0-0.7-2.1-2.5-0.6-1.5
Locomotion velocity, session 30.40.41.0-0.40.50.3-0.80.80.20.90.70.70.81.00.30.6
Locomotion distance, session 30.60.61.80.40.20.9-0.40.40.90.51.40.31.41.11.00.1
Stereotopy head waving bouts, day 30.80.91.6-1.30.8-1.2-1.01.0-1.20.7-0.90.7-0.80.3-1.21.0
Stereotopy head waving duration, day 30.81.02.2-1.00.6-1.4-0.10.1-1.40.1-1.50.5-1.5-0.6-1.50.6
Locomotion velocity, session 74.95.415.20.90.22.9-1.31.32.91.43.80.43.92.93.0-0.1
Locomotion distance, session 72.83.610.40.40.52.2-1.11.02.21.53.10.83.22.62.30.3
Stereotopy head waving bouts, day 70.40.41.3-0.3-0.5-0.30.1-0.1-0.2-0.7-1.0-0.6-1.1-1.1-0.2-0.7
Stereotopy head waving duration, day 70.30.41.3-0.2-0.0-0.7-0.20.2-0.7-0.4-1.1-0.3-1.1-0.7-0.7-0.0
Locomotion velocity, session 80.30.30.70.70.30.9-0.00.00.8-0.10.90.10.80.50.8-0.2
Locomotion distance, session 80.71.12.61.2-0.51.60.8-0.71.5-0.71.1-0.41.0-0.21.5-1.1
Degree of sensitization distance1.21.33.1-0.20.41.1-1.01.01.21.11.70.61.81.61.20.3
Degree of sensitization stereotypy0.30.30.80.5-0.50.20.5-0.50.3-0.9-0.4-0.8-0.5-0.80.2-0.8
Condit. Reinf. active minus inactive responses0.80.92.10.6-1.20.01.0-1.00.1-1.3-0.7-1.5-0.8-1.20.2-1.1
Condit. Reinf. active-inactive response ratio0.70.71.6-0.90.5-1.3-0.90.9-1.20.8-0.60.5-0.50.4-0.91.2
Condit. Reinf. active responses2.32.85.71.4-2.11.11.8-1.81.2-2.2-0.3-2.4-0.4-1.81.0-2.4
Condit. Reinf. inactive responses5.46.412.52.7-2.82.23.0-3.02.1-3.20.3-3.0-0.0-2.41.8-3.5
Incentive salience index mean3.33.98.41.7-2.81.02.2-2.21.1-2.6-0.4-2.9-0.5-2.21.1-2.5
Condit. Reinf. lever presses5.87.714.62.9-3.72.03.1-3.11.9-3.50.3-3.80.0-2.72.0-3.6
Time in familiar zone, hab. session 10.70.61.51.2-0.61.00.2-0.20.9-0.41.0-0.51.00.11.2-0.6
Time in novel zone, hab. session 13.73.66.5-2.62.4-1.7-2.01.9-1.72.1-1.12.2-0.91.3-2.02.2
Total zone transitions, hab. session 10.30.41.4-0.70.0-0.60.4-0.3-0.6-0.2-1.20.2-1.2-0.9-0.8-0.1
Total locomotion distance, hab. session 10.60.82.5-0.4-0.9-0.30.7-0.6-0.4-0.8-1.4-0.6-1.3-1.6-0.3-0.9
Locomotion velocity, hab. session 11.62.36.40.4-1.7-0.11.8-1.8-0.2-1.9-1.6-1.4-1.6-2.5-0.2-1.8
Time in familiar zone, hab. session 20.90.92.4-0.31.6-0.9-0.40.4-0.91.10.11.30.01.1-1.01.5
Time in novel zone, hab. session 20.20.20.5-0.5-0.40.4-0.30.30.3-0.3-0.4-0.3-0.4-0.60.3-0.7
Total zone transitions, hab. session 21.31.64.7-0.1-0.2-1.21.2-1.2-1.2-1.2-2.0-0.5-2.2-1.8-1.4-0.4
Total locomotion distance, hab. session 20.71.02.8-0.0-0.3-0.60.9-0.9-0.6-1.1-1.5-0.6-1.7-1.5-0.8-0.7
Locomotion velocity, hab. session 21.11.54.3-0.2-0.4-0.81.1-1.1-0.9-1.2-1.9-0.6-2.1-1.9-1.1-0.8
Novel to familiar place preference ratio1.21.23.60.6-0.91.50.5-0.51.6-1.30.3-1.30.2-0.81.2-1.9
Novelty place preference1.41.43.90.9-1.01.60.7-0.71.6-1.50.4-1.40.2-0.91.3-2.0
Time in novel zone, NPP test1.01.03.00.6-0.81.40.4-0.41.4-1.20.3-1.20.1-0.81.1-1.7
Total zone transitions, NPP test0.71.02.10.8-0.80.41.4-1.40.3-1.4-0.7-1.0-0.9-1.4-0.0-1.2
Total locomotion distance, NPP test1.41.93.91.2-1.41.11.7-1.71.0-1.8-0.4-1.5-0.5-1.60.7-2.0
Locomotion velocity, NPP test1.72.44.81.6-1.61.31.9-1.91.3-2.0-0.1-1.8-0.3-1.60.9-2.2
Pavlov. Cond. lever latency3.24.07.1-2.72.2-1.9-2.12.1-1.82.4-0.82.6-0.61.3-1.72.4
Pavlov. Cond. magazine entry latency0.81.12.31.5-1.01.20.9-0.91.2-0.80.9-1.10.9-0.11.2-1.1
Pavlov. Cond. change in total contacts1.81.93.61.5-1.31.11.6-1.71.1-1.80.1-1.8-0.1-1.20.9-1.9
Pavlov. Cond. index score2.93.66.52.6-2.01.82.1-2.11.8-2.20.9-2.40.6-1.21.7-2.3
Pavlov. Cond. latency score3.34.37.12.7-2.32.12.1-2.12.0-2.31.0-2.60.8-1.22.0-2.5
Pavlov. Cond. lever contacts3.44.07.32.7-2.21.82.2-2.21.7-2.40.8-2.60.5-1.41.7-2.4
Pavlov. Cond. magazine entry number0.30.40.9-1.00.5-0.8-0.70.8-0.70.6-0.40.6-0.30.3-0.70.7
Pavlov. Cond. intertrial magazine entries1.31.63.11.2-1.70.51.6-1.60.6-1.7-0.2-1.8-0.3-1.40.5-1.5
Pavlov. Cond. lever-magazine prob. diff.2.43.05.22.3-1.81.62.0-2.01.5-2.10.7-2.10.4-1.21.5-2.1
Pavlov. Cond. response bias0.91.12.61.6-1.10.81.4-1.40.8-1.20.5-1.30.4-0.60.8-1.1
Bone: apparent density0.20.30.9-0.1-0.60.50.7-0.70.4-0.7-0.2-0.3-0.2-0.90.5-0.9
Bone surface0.30.51.7-0.1-0.70.20.9-0.80.2-0.8-0.6-0.4-0.6-1.30.0-1.1
Bone volume0.30.41.6-0.2-0.40.20.9-0.80.2-0.8-0.6-0.1-0.6-1.30.1-1.0
Bone: connectivity density0.60.91.41.2-1.10.91.1-1.10.8-1.00.6-1.20.5-0.51.0-1.1
Bone: cortical apparent density1.21.64.8-0.41.4-0.1-1.51.5-0.11.61.21.01.22.2-0.01.6
Bone: cortical area0.10.10.6-0.8-0.00.1-0.30.30.00.2-0.20.4-0.1-0.3-0.2-0.2
Bone: cortical porosity2.32.55.01.3-1.80.32.1-2.10.2-2.2-0.7-1.9-0.9-2.20.4-1.9
Bone: cortical porosity1.82.04.41.1-1.60.11.9-1.90.1-2.0-0.8-1.5-0.9-2.10.2-1.6
Bone: cortical thickness0.20.30.90.3-0.30.90.1-0.10.8-0.40.6-0.40.5-0.10.6-0.8
Bone: cortical thickness0.50.61.0-0.30.61.0-1.01.00.80.61.00.51.01.00.6-0.0
Bone: cortical tissue density1.31.75.1-0.51.4-0.2-1.61.6-0.11.71.21.11.22.3-0.11.7
Bone: elastic displacement0.60.71.40.1-0.4-0.10.9-1.0-0.0-1.2-0.9-0.8-1.1-1.2-0.3-0.9
Bone: elastic work1.41.85.7-0.0-1.0-0.11.6-1.5-0.0-1.9-1.6-1.1-1.7-2.4-0.3-1.6
Bone: endosteal estimation0.20.52.0-1.4-0.1-0.8-0.30.3-0.80.4-1.00.7-0.7-0.7-0.80.3
Bone: endosteal perimeter0.40.82.6-1.6-0.2-1.1-0.60.6-1.10.6-1.20.7-0.9-0.6-1.10.4
Bone: final force0.50.81.80.6-1.11.20.6-0.61.2-0.80.5-0.90.6-0.71.2-1.4
Bone: final moment0.50.92.20.5-1.21.00.8-0.81.0-1.00.2-1.00.2-1.00.9-1.5
Bone: marrow area0.20.41.7-1.3-0.3-0.7-0.20.3-0.70.3-0.90.6-0.7-0.8-0.70.1
Bone: maximum diameter0.71.33.3-1.80.8-0.7-1.51.6-0.71.4-0.31.5-0.10.6-0.81.1
Bone: maximum force0.30.51.5-0.2-0.80.60.6-0.60.5-0.8-0.3-0.4-0.3-1.20.4-1.2
Bone: maximum moment0.40.82.5-0.3-1.00.40.9-0.80.4-1.0-0.7-0.6-0.6-1.60.3-1.4
Bone: minimum diameter0.20.41.5-0.9-0.7-0.10.2-0.1-0.1-0.4-0.9-0.0-0.8-1.2-0.5-0.8
Bone: periosteal estimation0.20.42.2-1.5-0.0-0.5-0.60.7-0.50.6-0.60.8-0.4-0.4-0.60.2
Bone: periosteal perimeter0.30.52.1-1.40.1-0.4-0.90.9-0.50.7-0.40.8-0.2-0.1-0.60.3
Bone: post-yield work0.50.61.70.30.11.2-0.20.31.20.51.20.41.30.71.1-0.3
Bone: stiffness0.30.41.00.3-1.00.80.4-0.30.7-0.50.3-0.50.4-0.60.7-1.0
Bone: tissue strength0.30.30.9-0.0-1.00.10.3-0.20.0-0.5-0.4-0.6-0.3-0.90.3-0.7
Bone: trabecular number0.40.61.20.5-1.00.90.7-0.70.9-0.70.5-0.70.5-0.61.1-1.1
Bone: trabecular spacing0.81.01.8-1.00.9-1.3-0.80.8-1.30.9-0.80.9-0.80.3-1.21.3
Bone: trabecular thickness1.21.42.81.2-0.81.31.5-1.41.5-1.40.5-1.00.3-1.01.2-1.7
Bone: trabecular tissue density0.81.12.0-1.21.0-1.4-0.60.6-1.40.9-1.01.2-0.90.1-1.41.2
Breakpoint value in progressive ratio session0.20.21.80.21.3-0.0-0.10.00.0-0.3-0.30.4-0.60.2-0.50.1
Distance traveled before self-admin1.51.63.7-1.40.6-1.7-0.20.2-1.7-0.0-1.90.6-1.9-1.0-1.80.6
Distance traveled after self-admin3.03.35.8-2.22.1-2.0-1.71.7-1.72.2-0.92.4-0.61.2-1.92.3
Delta time in closed arm before/after self-admin0.10.10.3-0.4-0.6-0.4-0.40.4-0.50.3-0.20.1-0.0-0.3-0.10.2
Delta time in open arm before/after self-admin0.10.10.2-0.1-0.20.3-0.30.30.20.10.3-0.00.30.10.4-0.1
Diff in mean of infusions in LGA sessions0.30.43.20.21.8-0.1-0.50.4-0.10.0-0.20.6-0.50.6-0.50.3
Extinction: sum of active levers before priming1.01.02.11.4-0.21.50.6-0.61.4-0.91.0-0.70.8-0.11.3-1.1
Active lever presses in extinction session 60.70.71.60.9-0.01.2-0.20.21.3-0.31.2-0.41.00.61.1-0.6
Delta distance traveled before/after self-admin2.42.65.6-1.22.0-0.5-1.81.8-0.42.40.82.10.92.3-0.62.0
Delta ambulatory time before/after self-admin1.11.22.7-0.81.5-0.3-1.11.0-0.31.60.61.50.61.6-0.51.3
Time in closed arm before self-admin0.10.20.4-0.7-0.1-0.4-0.30.3-0.20.60.10.40.20.3-0.30.6
Time in closed arm after self-admin0.20.20.5-0.60.1-0.70.1-0.1-0.50.4-0.30.3-0.20.1-0.60.5
Time in open arm before self-admin0.30.31.1-0.41.1-0.5-0.40.4-0.60.4-0.50.8-0.60.2-0.70.4
Time in open arm after self-admin0.10.10.3-0.40.3-0.3-0.40.5-0.40.4-0.10.5-0.10.1-0.10.4
Sum of active levers in priming session hrs 5-63.03.06.3-1.02.1-0.6-2.52.5-0.72.30.62.10.82.2-0.52.0
Time to tail flick, vehicle, before self-admin3.73.78.83.0-1.12.51.8-1.82.4-1.91.5-1.91.2-0.42.0-2.1
Time to tail flick, vehicle, after self-admin0.80.83.30.01.80.2-0.70.60.21.00.71.00.61.6-0.31.0
Time to tail flick, test, before self-admin0.60.61.80.2-1.00.21.3-1.30.4-0.8-0.3-0.6-0.3-1.10.2-0.8
Time to tail flick, test, after self-admin1.41.53.71.2-1.01.6-0.10.11.60.11.8-0.81.90.91.7-0.6
Delta time to tail flick, vehicle, before/after SA1.21.23.1-1.01.8-0.4-1.31.2-0.51.40.21.40.21.5-0.71.3
Delta time to tail flick, test, before/after SA1.61.53.30.20.30.8-1.61.60.71.31.60.51.81.80.90.7
Ambulatory time before self-admin0.60.62.0-0.40.4-0.80.4-0.4-0.8-0.6-1.30.2-1.4-1.0-1.0-0.1
Ambulatory time after self-admin2.22.44.3-1.81.8-2.0-0.90.9-1.71.3-1.31.8-1.30.4-2.11.7
Total heroin consumption0.30.41.20.10.9-0.50.4-0.4-0.5-0.4-0.90.3-1.1-0.5-0.8-0.0
Area under the delay curve0.50.51.40.1-0.70.21.1-1.0-0.0-0.8-0.5-0.5-0.6-1.2-0.1-0.8
Delay disc. indifference point, 0s delay0.60.71.7-0.4-0.8-0.90.5-0.4-0.8-0.6-1.3-0.6-1.2-1.3-0.6-0.1
Delay disc. indifference point, 16s delay0.40.41.10.4-0.20.11.0-1.0-0.0-0.8-0.5-0.3-0.6-0.9-0.3-0.8
Delay disc. indifference point, 2s delay1.51.73.8-1.70.2-2.0-0.40.5-1.80.7-1.80.9-1.5-0.8-1.71.0
Delay disc. indifference point, 24s delay0.00.00.2-0.20.2-0.10.1-0.1-0.10.2-0.10.4-0.1-0.0-0.2-0.0
Delay disc. indifference point, 4s delay0.50.51.3-1.10.2-0.8-0.50.5-1.10.5-0.90.7-0.7-0.2-0.90.7
Delay disc. indifference point, 8s delay0.90.92.10.9-0.91.01.4-1.40.9-1.10.3-0.90.2-0.80.7-1.2
Delay discount exponential model param0.40.41.20.00.7-0.1-1.00.90.10.70.50.30.51.10.10.7
Delay discount hyperbolic model param0.40.41.30.40.50.3-0.80.70.50.50.90.10.81.10.50.4
Fecal boli incidents, locomotor time 11.31.44.30.9-0.10.32.0-2.10.2-1.6-0.8-0.6-1.1-1.6-0.3-1.2
Change in fecal boli incidents, locomotor task1.51.53.5-1.60.5-1.2-1.91.9-1.31.4-0.30.7-0.10.9-0.71.5
Time >=10cm from walls, locomotor time 10.80.81.61.0-1.30.41.2-1.20.6-1.1-0.0-1.2-0.1-0.90.4-1.0
Bouts of movement, locomotor time 10.50.51.5-0.11.2-0.8-0.50.5-0.70.8-0.10.8-0.20.8-0.81.1
Total resting periods, locomotor time 10.70.82.0-0.41.4-0.9-0.80.7-0.81.0-0.11.1-0.11.0-0.91.3
Rest time, locomotor task time 11.41.53.0-1.41.3-1.7-0.40.4-1.50.8-1.31.4-1.30.0-1.71.2
Distance moved, locomotor task time 10.80.91.90.9-1.01.3-0.20.21.3-0.21.2-1.01.30.51.4-0.7
Vertical activity count, locomotor time 10.20.20.5-0.3-0.0-0.60.1-0.1-0.5-0.2-0.7-0.1-0.7-0.4-0.70.1
Time >=10cm from walls, locomotor time 21.11.22.5-1.20.6-1.6-0.20.2-1.50.4-1.40.7-1.4-0.4-1.51.1
Bouts of movement, locomotor time 20.60.62.9-0.41.7-0.4-0.70.6-0.40.9-0.11.2-0.20.9-0.80.7
Total resting periods, locomotor time 20.40.42.6-0.11.6-0.2-0.40.3-0.20.6-0.11.1-0.20.8-0.60.5
Rest time, locomotor task time 20.20.21.50.01.20.10.2-0.20.20.20.00.8-0.10.3-0.3-0.1
Distance moved, locomotor task time 20.60.71.90.8-1.40.70.4-0.40.8-0.90.2-1.30.2-0.60.8-1.0
Vertical activity count, locomotor time 20.91.02.2-1.00.4-1.5-0.10.1-1.40.1-1.50.4-1.4-0.7-1.40.7
Weight adjusted by age1.41.64.1-1.70.0-2.0-1.01.0-1.90.8-1.50.4-1.3-0.3-1.51.2
Seeking ratio, delayed vs. immediate footshock0.20.20.7-0.2-0.8-0.5-0.50.5-0.50.1-0.2-0.7-0.1-0.0-0.00.2
Locomotion in novel chamber1.11.43.71.0-0.70.41.9-1.90.5-1.6-0.5-0.9-0.7-1.60.1-1.4
Locomotion in novel chamber post-restriction0.40.41.0-1.00.6-0.3-0.80.8-0.50.9-0.21.0-0.00.3-0.10.8
Progressive ratio0.40.51.70.41.30.3-0.20.20.70.70.81.00.71.20.00.5
Food seeking constrained by brief footshock4.35.214.8-1.53.8-1.4-2.32.2-1.22.70.23.10.12.9-2.02.9
Seeking ratio, punishment vs. effort0.91.22.1-1.40.6-1.2-1.41.4-1.41.1-0.60.8-0.40.5-1.01.3
Run reversals in cocaine runway, females0.20.20.60.0-0.20.5-0.30.30.50.50.70.50.80.50.50.3
Run reversals in cocaine runway, males1.01.02.60.60.10.21.6-1.60.4-1.3-0.8-0.3-1.1-1.3-0.4-1.2
Latency to leave start box in cocaine runway1.31.42.7-1.41.0-1.6-0.90.9-1.60.7-1.30.9-1.3-0.0-1.41.2
Latency to leave start box in cocaine runway, F0.50.51.1-0.70.7-0.9-0.50.5-1.00.2-1.00.4-1.0-0.2-1.00.5
Latency to leave start box in cocaine runway, M0.10.10.1-0.30.1-0.40.1-0.1-0.40.1-0.40.2-0.3-0.2-0.40.2
Cd content in liver0.20.30.60.70.10.7-0.20.20.60.00.8-0.20.70.60.7-0.0
Co content in liver3.84.59.3-2.03.1-1.7-2.02.0-1.62.6-0.43.0-0.31.9-1.92.9
Cu content in liver1.11.32.8-1.71.4-1.1-0.90.8-1.21.1-0.91.3-0.80.6-1.41.3
Fe content in liver0.20.20.50.2-0.70.5-0.10.10.50.10.6-0.50.70.20.4-0.2
K content in liver0.50.51.30.9-0.60.90.3-0.31.0-0.11.1-0.41.10.40.7-0.3
Mg content in liver0.20.20.5-0.20.30.2-0.40.40.20.70.50.60.60.6-0.10.5
Mn content in liver0.20.20.6-0.30.4-0.1-0.30.3-0.20.70.40.80.50.50.10.7
Na content in liver3.03.29.0-0.2-1.7-1.21.9-1.8-1.2-2.0-2.4-1.4-2.4-3.0-0.7-1.2
Rb content in liver0.30.31.00.80.10.6-0.10.00.50.11.0-0.30.90.90.60.1
Se content in liver1.51.85.1-1.2-0.5-1.70.7-0.7-1.6-0.7-2.3-0.3-2.2-1.8-1.1-0.1
Sr content in liver0.40.41.9-1.40.1-0.5-0.40.5-0.70.4-0.70.5-0.6-0.3-0.60.3
Zn content in liver1.51.64.0-0.6-0.7-1.01.3-1.3-0.9-1.2-1.9-0.7-2.0-2.0-1.1-0.7