Hub : Genes

Tnrc6b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000024907	0.05	0.03	6.1e-04	0.01	0.01	0.01	0.01	4.3e-02	4.1e-02	8.3e-03	2.4e-02
2	Brain	gene expression	ENSRNOG00000024907	0.09	0.06	1.4e-04	0.06	0.05	0.05	0.05	4.3e-06	1.1e-05	3.5e-05	1.2e-05
3	LHb	alternative polyA	ENSRNOT00000091270	0.16	0.1	2.7e-03	0.04	0.06	0.07	0.05	3.6e-02	1.7e-02	1.0e-02	2.2e-02
4	PL	gene expression	ENSRNOG00000024907	0.04	0.03	2.9e-03	0.02	0.02	0.01	0.01	1.2e-02	6.0e-03	7.5e-02	2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	0.5	1.7	4.4	-2.1	-0.3	-0.6	-1.3
BMI without tail	0.1	0.3	0.8	-0.1	0.9	-0.6	0.1
Body weight	0.9	3.8	9.5	-3.1	-1.1	-0.8	-2.0
Epididymis fat weight	1.5	3.4	8.8	-3.0	-0.3	-2.1	-0.8
Glucose	0.1	0.2	0.5	0.5	0.7	0.0	0.0
Heart weight	0.6	0.9	2.2	-1.5	-0.0	-0.1	-1.1
Left kidney weight	4.9	14.0	36.5	-6.0	-2.5	-1.6	-3.2
Right kidney weight	6.0	17.2	41.3	-6.4	-3.2	-0.8	-4.1
Tail length	0.1	0.4	0.6	0.5	0.8	-0.7	0.7
Length with tail	0.2	0.8	2.1	-1.5	-0.6	-0.6	-0.7
Length without tail	1.1	2.3	4.5	-2.1	-1.7	-0.0	-1.5
Liver weight, left	0.8	1.3	3.7	-0.9	0.6	-1.9	0.4
Liver weight, right	2.7	4.6	12.5	-1.4	1.5	-3.5	1.2
Parametrial fat weight	0.1	0.2	0.3	-0.6	-0.1	-0.5	-0.1
Retroperitoneal fat weight	1.9	6.2	16.3	-4.0	-0.7	-2.5	-1.4
Intraocular pressure	0.3	0.4	0.8	-0.9	-0.7	-0.5	-0.3
Extensor digitorum longus weight	0.2	0.8	1.5	1.0	1.2	0.2	0.8
Soleus weight	0.3	0.9	2.2	0.7	-1.0	1.5	-0.2
Tibialis anterior weight	0.3	1.2	3.2	1.2	-0.0	1.8	0.1
Tibia length	1.0	2.8	3.8	-1.9	-1.9	0.7	-1.8
Number of licking bursts	0.5	0.6	1.8	1.3	-0.0	0.5	0.6
Food consumed during 24 hour testing period	2.2	2.6	3.9	-2.0	-1.5	0.7	-1.9
Times rat made contact with spout	0.8	0.9	1.5	-0.6	-1.2	1.1	-0.9
Mean time between licks in bursts	0.6	0.8	1.3	1.1	1.1	-0.1	0.9
Mean num. licks in bursts	1.0	1.2	3.2	-1.8	-0.7	-0.2	-0.9
Std. dev. time between licks in bursts	0.7	0.8	1.7	1.3	-0.4	1.1	-0.3
Water consumed over 24 hours	0.9	1.1	1.8	-0.8	-1.3	0.8	-1.1
Indifference point 0 sec	0.1	0.2	0.4	0.5	0.1	0.6	-0.1
Indifference point AUC	1.4	1.6	3.3	0.2	-1.7	1.8	-0.5
Indifference point function ln k	1.3	1.9	4.5	-1.0	1.4	-2.1	0.4
Indifference point function log k	1.3	1.9	4.5	-1.0	1.4	-2.1	0.4
Delay discounting total patch changes 0 sec	0.1	0.2	0.5	0.6	0.1	0.7	-0.1
Delay discounting total patch changes 12 sec	0.5	0.6	1.0	-0.2	-0.9	1.0	-0.7
Delay discounting total patch changes 18 sec	1.7	2.2	4.3	-0.2	-1.5	2.1	-1.5
Delay discounting total patch changes 24 sec	0.4	0.5	1.3	0.5	-0.7	1.1	-0.3
Delay discounting total patch changes 6 sec	1.9	2.9	6.0	0.2	-1.8	2.5	-1.5
Delay discounting time to switch 0 sec	0.1	0.1	0.3	-0.2	0.5	-0.3	-0.4
Delay discounting water rate 0 sec	0.1	0.2	0.6	0.2	-0.3	0.8	-0.2
Delay discounting water rate 12 sec	0.6	0.9	1.3	1.1	1.0	-0.5	0.9
Delay discounting water rate 18 sec	0.4	0.6	1.2	1.1	-0.2	1.0	0.1
Delay discounting water rate 24 sec	0.0	0.1	0.2	-0.1	0.3	-0.4	0.0
Delay discounting water rate 6 sec	1.6	2.4	3.6	1.8	1.5	-0.8	1.9
Locomotor activity	0.5	0.8	1.9	-1.4	-0.2	-0.7	-0.8
Locomotor testing distance	0.2	0.3	0.4	0.5	0.6	-0.6	0.5
Locomotor testing rearing	0.3	0.5	1.1	-1.1	-0.0	-0.9	-0.4
Light reinforcement 1	0.0	0.1	0.1	0.3	-0.1	0.3	-0.1
Light reinforcement 2	1.0	1.3	3.2	-0.7	1.1	-1.8	0.7
Reaction time number correct	1.2	1.7	3.2	1.2	0.9	-1.1	1.8
Reaction time mean minus median	0.1	0.1	0.3	0.1	0.5	-0.5	0.2
Reaction time mean minus median AUC	0.4	0.6	1.2	-0.5	0.8	-1.1	0.2
Reaction time num false alarms	0.2	0.3	0.5	0.3	0.7	-0.7	0.5
Reaction time num false alarms AUC	0.4	0.5	0.7	0.6	0.8	-0.7	0.8
Reaction time trials correct on left	1.2	1.7	3.2	1.2	0.9	-1.1	1.8
Reaction time trials on left	1.3	1.8	3.4	1.3	1.0	-1.2	1.9
Reaction time mean	0.3	0.4	0.9	0.6	1.0	-0.6	0.4
Reaction time mean AUC	0.3	0.4	0.7	0.6	0.8	-0.6	0.4
Median of all reaction times	0.3	0.4	0.8	0.8	0.9	-0.4	0.4
Reaction time omissions	0.4	0.5	0.7	0.7	0.7	-0.5	0.8
Reaction time false alarm rate	0.1	0.1	0.2	-0.1	0.5	-0.2	-0.0
Reaction time premature initiation rate	0.7	1.0	1.7	-0.0	-0.9	1.2	-1.3
Reaction time premature initiations	0.2	0.2	0.3	0.3	-0.5	0.5	-0.5
Std. dev. reaction times	0.2	0.3	0.6	-0.1	0.7	-0.8	0.1
Reaction time trials completed	1.3	1.8	3.4	1.3	1.0	-1.2	1.9
Reaction time trials AUC	0.9	1.3	2.5	1.0	0.8	-1.1	1.6
Social response proportion	0.2	0.2	0.4	-0.3	0.6	-0.1	-0.4
Social responses	0.2	0.2	0.6	0.4	-0.5	0.8	-0.2
Social time	0.9	1.1	2.8	1.7	0.3	1.2	0.4
Conditioned locomotion	0.1	0.1	0.4	-0.6	0.1	-0.3	-0.0
Cocaine response after cond. corrected	0.2	0.2	0.3	-0.4	-0.4	0.4	-0.5
Cocaine response after cond. not corrected	0.0	0.0	0.0	-0.0	0.2	0.1	-0.2
Cocaine response before conditioning	0.6	0.8	1.3	0.8	1.2	-0.7	0.8
Saline control response	1.4	1.9	2.5	1.0	1.5	-1.4	1.6
Condit. Reinf. active minus inactive responses	1.2	1.5	2.8	-0.2	-1.7	1.5	-1.0
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.1	-0.6	-1.5	1.4	-1.4
Condit. Reinf. active responses	0.9	1.2	2.7	-0.7	-1.6	0.7	-1.0
Condit. Reinf. inactive responses	0.4	0.6	1.3	-0.8	-1.2	-0.1	-0.5
Condit. Reinf. lever presses	0.2	0.2	0.6	0.6	-0.1	0.7	-0.1
Condit. Reinf. lever reinforcers received	0.6	0.9	2.0	-0.4	-1.4	0.7	-0.9
Pavlov. Cond. lever latency	0.4	0.6	1.5	-1.2	-0.8	-0.5	-0.3
Pavlov. Cond. magazine entry latency	1.4	1.6	4.0	1.4	-0.5	2.0	-0.4
Pavlov. Cond. change in total contacts	1.4	2.0	4.1	0.2	-1.0	2.0	-1.7
Pavlov. Cond. index score	0.7	1.0	2.0	1.4	0.1	1.4	-0.1
Pavlov. Cond. latency score	0.9	1.2	2.4	1.5	-0.0	1.6	-0.1
Pavlov. Cond. lever contacts	0.4	0.6	1.5	1.2	0.9	0.3	0.3
Pavlov. Cond. magazine entry number	0.6	0.8	1.9	-1.0	0.4	-1.4	0.4
Pavlov. Cond. intertrial magazine entries	1.0	1.3	2.9	-1.7	-1.0	0.0	-1.1
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.0	1.4	0.2	1.2	-0.0
Pavlov. Cond. response bias	0.4	0.6	1.1	1.0	0.1	1.1	-0.3
Conditioned reinforcement - actives	0.6	0.6	1.1	-0.4	-1.0	1.1	-0.1
Conditioned reinforcement - inactives	1.0	1.2	2.8	0.6	-0.9	1.7	-0.7
Conditioned locomotion	2.4	2.8	3.7	-1.5	-1.9	1.5	-1.8
Intermittent access intake day 1-15 change	0.6	0.6	1.1	0.8	0.7	0.0	1.1
Intermittent access intake escalation	0.5	0.5	0.9	0.8	0.7	-0.0	0.9
Intermittent access intake escalation 2	0.2	0.2	0.3	0.6	0.6	0.2	0.6
Intermitt. access day 1 inactive lever presses	0.6	0.7	1.2	-0.4	-0.7	0.9	-1.1
Intermitt. access day 15 inactive lever presses	0.9	1.0	1.4	-0.3	-1.2	1.2	-1.0
Intermitt. access escalation Index	0.1	0.1	0.1	0.4	0.2	0.1	0.2
Intermittent access day 1 total infusions	1.4	1.6	2.4	-1.0	-1.5	1.0	-1.5
Intermittent access day 15 total infusions	0.5	0.6	1.1	-0.0	-0.9	1.0	-0.7
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.4	-0.1	-0.5	0.6	-0.3
Intermittent access total infusions	1.2	1.3	1.9	-0.7	-1.3	1.1	-1.4
Intermittent access day 1 locomotion	1.0	1.0	1.6	-0.9	-0.9	0.9	-1.3
Intermittent access day 15 total locomotion	0.6	0.6	1.0	-0.8	-0.9	0.4	-1.0
Intermittent access total locomotion	1.6	1.8	2.8	-1.2	-1.4	1.0	-1.7
Intermittent access standard deviation	0.6	0.6	1.0	-0.9	-0.6	0.5	-1.0
Cocaine induced anxiety	0.8	0.9	2.1	-1.5	-0.4	-0.3	-1.1
Post-drug Anxiety	0.4	0.4	0.8	-0.8	-0.4	-0.1	-0.9
Baseline Anxiety	0.7	0.8	2.1	1.5	0.4	0.1	0.9
Lifetime Intake	2.2	2.4	3.6	-1.2	-1.7	1.3	-1.9
Incentive Sensitization - Responses	0.3	0.3	0.6	0.7	0.1	-0.2	0.7
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	0.5	-0.0	-0.2	0.5
Progressive ratio test 1 active lever presses	2.3	2.4	3.1	-1.0	-1.8	1.6	-1.6
Progressive ratio test 1 breakpoint	1.2	1.2	1.7	-0.7	-1.3	1.2	-1.1
Progressive ratio test 1 inactive lever presses	0.8	0.8	1.7	-0.4	-0.5	1.3	-1.1
Progressive ratio test 2 active lever presses	1.0	1.1	2.0	-0.1	-1.4	1.3	-0.8
Progressive ratio test 2 breakpoint	1.3	1.4	2.4	-0.4	-1.6	1.4	-1.1
Progressive ratio test 2 inactive lever presses	0.8	0.9	2.2	0.6	-0.8	1.5	-0.5
Total sessions with >9 infusions	2.4	2.6	3.8	-1.7	-1.8	0.9	-2.0
Short access day 1 total inactive lever presses	3.7	4.1	5.8	-0.6	-2.2	2.4	-2.3
Short access day 10 total inactive lever presses	0.0	0.0	0.1	-0.1	-0.2	0.0	-0.3
Short access day 1 total infusions	0.9	1.0	1.6	-0.9	-1.0	0.7	-1.3
Short access day 10 total infusions	2.6	2.9	4.5	-2.0	-1.6	0.8	-2.1
Short access total infusions	3.2	3.5	5.7	-1.9	-1.9	1.0	-2.4
Short access day 1 locomotion	0.3	0.3	0.5	-0.2	-0.3	0.7	-0.7
Short access day 10 total locomotion	0.1	0.1	0.3	-0.2	0.6	0.4	-0.1
Short access total locomotion	1.6	1.6	2.6	-1.5	-0.9	0.8	-1.6
Compulsive drug intake	1.0	1.0	1.9	1.4	-0.1	1.1	1.0
One hour access (0.3 mA shock)	0.2	0.2	0.7	0.4	-0.3	0.9	0.0
One hour access (shock baseline)	0.1	0.1	0.2	-0.5	0.1	-0.3	-0.4
Number of responses in last shaping day	2.2	2.2	4.1	-0.0	-1.4	2.0	-1.7
Context. condit. distance diff. score	3.0	3.7	6.9	-2.6	1.0	-2.6	0.2
Locomotion velocity, session 1	1.1	1.1	2.5	-0.0	-1.6	1.2	-0.8
Locomotion distance, session 1	1.5	1.9	3.5	1.5	-1.3	1.9	0.0
Locomotion velocity, session 2	0.2	0.2	0.5	-0.4	-0.5	0.1	-0.7
Locomotion distance, session 2	2.3	3.3	7.2	1.6	-1.7	2.7	-0.9
Locomotion velocity, session 3	1.0	1.1	2.8	-0.2	0.7	-1.7	1.1
Locomotion distance, session 3	1.1	1.2	2.9	1.2	0.4	-0.5	1.7
Stereotopy head waving bouts, day 3	1.2	1.4	2.3	-1.3	-1.1	0.7	-1.5
Stereotopy head waving duration, day 3	1.9	2.3	4.7	-2.2	-0.9	-0.0	-1.9
Locomotion velocity, session 7	0.3	0.3	0.9	-0.6	0.1	-1.0	0.1
Locomotion distance, session 7	0.5	0.6	1.2	-0.3	-1.1	0.7	-0.7
Stereotopy head waving bouts, day 7	1.1	1.3	3.2	-1.3	0.5	-1.8	-0.1
Stereotopy head waving duration, day 7	1.8	2.2	5.4	-1.1	1.4	-2.3	0.5
Locomotion velocity, session 8	1.2	1.4	2.8	-1.7	-1.1	0.1	-1.3
Locomotion distance, session 8	0.4	0.6	1.4	-0.7	0.7	-1.2	0.4
Degree of sensitization distance	2.1	2.1	4.1	-1.9	-0.8	0.5	-2.0
Degree of sensitization stereotypy	1.4	1.5	4.1	-1.0	0.9	-2.0	0.5
Condit. Reinf. active minus inactive responses	0.1	0.2	0.3	0.4	-0.6	0.4	-0.1
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.4	-0.3	-0.1	-0.7	0.3
Condit. Reinf. active responses	0.7	0.8	2.5	1.6	0.4	0.4	0.7
Condit. Reinf. inactive responses	1.8	2.1	5.5	2.3	1.2	0.5	1.2
Incentive salience index mean	0.2	0.2	0.6	0.8	-0.4	0.4	0.0
Condit. Reinf. lever presses	0.3	0.4	1.3	1.2	0.1	0.4	0.1
Time in familiar zone, hab. session 1	1.2	1.1	2.1	-0.5	-1.4	1.2	-0.9
Time in novel zone, hab. session 1	0.8	0.8	1.7	-0.2	1.3	-1.1	0.5
Total zone transitions, hab. session 1	1.9	2.7	6.5	2.5	0.5	0.2	2.0
Total locomotion distance, hab. session 1	1.7	2.5	4.7	2.2	0.8	-0.5	2.1
Locomotion velocity, hab. session 1	1.4	2.0	5.1	2.3	0.4	-0.0	1.7
Time in familiar zone, hab. session 2	1.0	1.1	1.7	0.4	1.0	-1.2	1.3
Time in novel zone, hab. session 2	1.0	1.0	1.4	-0.4	-0.9	1.2	-1.2
Total zone transitions, hab. session 2	1.3	1.7	3.6	0.9	-1.5	1.9	-0.6
Total locomotion distance, hab. session 2	0.8	1.0	2.3	1.1	-0.7	1.5	-0.3
Locomotion velocity, hab. session 2	1.1	1.5	3.2	1.5	-0.8	1.8	-0.2
Novel to familiar place preference ratio	0.6	0.6	1.8	-1.4	0.1	-0.7	-0.2
Novelty place preference	0.9	0.9	2.4	-1.6	0.2	-1.1	-0.1
Time in novel zone, NPP test	1.1	1.1	3.2	-1.8	0.0	-1.1	-0.2
Total zone transitions, NPP test	1.6	2.2	5.9	2.4	-0.2	1.0	1.4
Total locomotion distance, NPP test	0.8	1.1	2.8	1.7	-0.4	1.0	0.6
Locomotion velocity, NPP test	1.1	1.5	4.4	2.1	-0.0	0.9	1.0
Pavlov. Cond. lever latency	0.4	0.5	1.5	-1.2	-0.4	0.1	-0.5
Pavlov. Cond. magazine entry latency	0.4	0.5	1.2	0.7	-0.6	1.1	-0.3
Pavlov. Cond. change in total contacts	1.4	1.5	3.3	1.0	-1.1	1.8	-0.7
Pavlov. Cond. index score	0.2	0.3	0.5	0.4	-0.5	0.7	-0.4
Pavlov. Cond. latency score	0.1	0.1	0.2	0.5	-0.2	0.5	-0.2
Pavlov. Cond. lever contacts	0.3	0.4	1.4	1.2	0.2	0.4	0.2
Pavlov. Cond. magazine entry number	0.2	0.2	0.4	-0.6	0.5	-0.6	0.0
Pavlov. Cond. intertrial magazine entries	0.9	1.0	2.4	1.1	-0.6	1.6	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.4	0.6	-0.4	0.7	-0.2
Pavlov. Cond. response bias	0.3	0.3	0.6	0.7	-0.5	0.8	-0.3
Bone: apparent density	0.1	0.1	0.4	0.3	0.0	0.6	-0.2
Bone surface	0.3	0.6	1.4	0.2	-0.9	1.2	-0.5
Bone volume	0.1	0.2	0.5	-0.1	-0.5	0.7	-0.4
Bone: connectivity density	0.1	0.2	0.6	0.0	-0.3	0.8	-0.4
Bone: cortical apparent density	0.7	0.9	1.8	1.2	0.5	-0.5	1.3
Bone: cortical area	1.6	2.4	4.2	-2.0	-1.3	0.6	-1.9
Bone: cortical porosity	0.4	0.4	1.0	-1.0	0.2	-0.3	-0.8
Bone: cortical porosity	1.0	1.1	2.3	-1.5	-0.3	-0.1	-1.4
Bone: cortical thickness	0.6	1.0	1.3	-1.1	-1.0	0.8	-1.1
Bone: cortical thickness	1.5	1.8	2.5	-0.9	-1.6	1.3	-1.4
Bone: cortical tissue density	0.7	0.9	1.8	1.1	0.5	-0.5	1.3
Bone: elastic displacement	0.0	0.0	0.0	-0.1	0.1	-0.1	0.2
Bone: elastic work	1.8	2.3	4.7	-2.2	-0.9	0.5	-1.9
Bone: endosteal estimation	0.6	1.4	2.5	-1.4	-1.0	0.4	-1.6
Bone: endosteal perimeter	0.8	1.5	4.0	-2.0	-0.4	-0.5	-1.3
Bone: final force	3.3	5.4	7.5	-2.7	-2.2	1.4	-2.7
Bone: final moment	3.6	5.9	8.3	-2.7	-2.4	1.6	-2.9
Bone: marrow area	0.7	1.5	2.8	-1.4	-1.0	0.5	-1.7
Bone: maximum diameter	2.9	5.3	10.1	-3.2	-1.8	0.5	-2.8
Bone: maximum force	4.8	8.4	11.7	-3.3	-2.8	1.8	-3.4
Bone: maximum moment	5.1	8.9	12.5	-3.4	-2.9	1.9	-3.5
Bone: minimum diameter	0.7	1.3	2.2	-1.4	-0.8	0.5	-1.5
Bone: periosteal estimation	1.4	2.9	4.8	-2.2	-1.4	0.6	-2.2
Bone: periosteal perimeter	2.1	3.5	8.3	-2.9	-1.1	-0.2	-2.1
Bone: post-yield work	2.9	4.0	5.4	-1.0	-2.3	2.3	-2.1
Bone: stiffness	3.2	5.1	8.2	-2.4	-2.0	1.5	-2.9
Bone: tissue strength	0.2	0.1	0.4	-0.6	-0.4	0.2	-0.3
Bone: trabecular number	0.2	0.3	0.4	-0.0	0.5	-0.6	0.6
Bone: trabecular spacing	2.8	3.6	4.9	-1.6	-2.2	1.6	-2.2
Bone: trabecular thickness	0.9	1.1	1.9	0.5	1.4	-1.2	0.9
Bone: trabecular tissue density	0.5	0.7	1.6	1.2	0.7	0.8	0.2
Breakpoint value in progressive ratio session	0.1	0.1	0.2	0.1	-0.1	0.5	-0.4
Distance traveled before self-admin	0.1	0.1	0.3	0.1	-0.2	0.5	-0.3
Distance traveled after self-admin	2.0	2.2	3.7	-0.3	-1.5	1.9	-1.6
Delta time in closed arm before/after self-admin	0.7	0.7	1.4	-1.2	-0.9	-0.1	-0.7
Delta time in open arm before/after self-admin	0.3	0.3	0.9	0.9	0.5	0.1	0.3
Diff in mean of infusions in LGA sessions	0.8	0.9	1.5	-0.4	-1.2	1.1	-0.7
Extinction: sum of active levers before priming	0.4	0.4	0.7	0.1	-0.7	0.8	-0.5
Active lever presses in extinction session 6	0.2	0.2	0.3	-0.1	-0.4	0.4	-0.6
Delta distance traveled before/after self-admin	1.2	1.2	2.2	-0.7	-1.5	0.9	-1.2
Delta ambulatory time before/after self-admin	1.9	2.1	3.4	-0.7	-1.9	1.4	-1.6
Time in closed arm before self-admin	1.3	1.5	3.1	1.6	0.3	1.8	-0.3
Time in closed arm after self-admin	0.9	0.9	1.7	-1.0	-0.8	0.5	-1.3
Time in open arm before self-admin	0.9	0.9	1.7	-0.4	0.7	-1.3	1.1
Time in open arm after self-admin	1.4	1.6	2.2	0.8	1.5	-1.0	1.5
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.3	0.3	0.1	0.1
Time to tail flick, vehicle, before self-admin	0.3	0.3	0.5	-0.1	-0.7	0.6	-0.5
Time to tail flick, vehicle, after self-admin	0.7	0.7	1.8	1.4	0.6	-0.2	0.8
Time to tail flick, test, before self-admin	0.0	0.0	0.0	0.2	-0.2	-0.2	0.2
Time to tail flick, test, after self-admin	0.7	0.8	2.0	1.4	0.6	0.2	0.8
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.5	0.7	0.6	-0.1	0.3
Delta time to tail flick, test, before/after SA	1.7	1.5	3.4	1.8	1.1	0.2	1.2
Ambulatory time before self-admin	0.1	0.1	0.3	0.6	0.2	0.4	0.3
Ambulatory time after self-admin	1.2	1.3	2.9	0.8	-1.1	1.7	-0.8
Total heroin consumption	0.6	0.7	1.1	-0.4	-1.0	1.0	-0.8
Area under the delay curve	1.1	1.2	2.5	0.5	-1.3	1.6	-0.5
Delay disc. indifference point, 0s delay	0.9	1.0	1.8	-1.1	-0.8	0.5	-1.3
Delay disc. indifference point, 16s delay	1.2	1.3	2.9	1.2	-0.9	1.7	-0.0
Delay disc. indifference point, 2s delay	1.0	1.1	2.0	-0.3	-1.4	1.2	-0.9
Delay disc. indifference point, 24s delay	1.9	1.9	4.2	0.1	-2.0	1.6	-0.8
Delay disc. indifference point, 4s delay	1.4	1.5	2.8	0.1	-1.3	1.7	-1.1
Delay disc. indifference point, 8s delay	0.8	0.8	1.9	0.9	-0.8	1.4	-0.1
Delay discount exponential model param	1.1	1.2	2.5	-0.6	1.2	-1.6	0.4
Delay discount hyperbolic model param	1.1	1.2	2.6	-0.5	1.3	-1.6	0.6
Fecal boli incidents, locomotor time 1	1.5	1.6	3.6	0.2	-1.2	1.9	-1.2
Change in fecal boli incidents, locomotor task	0.4	0.4	0.9	-0.4	-0.2	-0.9	0.6
Time >=10cm from walls, locomotor time 1	0.6	0.6	1.1	-0.7	-0.8	0.5	-1.1
Bouts of movement, locomotor time 1	0.7	0.8	1.5	-1.2	-1.0	-0.1	-0.8
Total resting periods, locomotor time 1	0.7	0.8	1.1	-1.1	-1.1	0.2	-1.0
Rest time, locomotor task time 1	0.9	1.0	1.4	-1.1	-1.0	0.6	-1.2
Distance moved, locomotor task time 1	0.7	0.8	1.4	-0.3	1.0	-1.2	0.7
Vertical activity count, locomotor time 1	0.0	0.0	0.1	0.1	0.3	0.2	-0.0
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.5	0.0	-0.4	0.7	-0.5
Bouts of movement, locomotor time 2	0.2	0.2	0.5	-0.6	0.0	-0.7	-0.2
Total resting periods, locomotor time 2	0.2	0.2	0.3	-0.5	-0.4	-0.2	-0.5
Rest time, locomotor task time 2	0.2	0.3	0.5	0.1	-0.7	0.7	-0.3
Distance moved, locomotor task time 2	0.6	0.7	1.3	-0.8	0.8	-1.1	0.4
Vertical activity count, locomotor time 2	0.2	0.3	0.6	-0.8	-0.2	0.1	-0.6
Weight adjusted by age	0.4	0.4	0.7	0.4	0.6	-0.7	0.9
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	2.4	1.5	0.6	-0.0	0.6
Locomotion in novel chamber	4.5	5.6	8.7	2.4	2.5	-1.1	2.9
Locomotion in novel chamber post-restriction	0.6	0.7	1.0	0.9	0.9	-0.5	1.0
Progressive ratio	0.2	0.2	0.6	0.1	-0.2	0.8	-0.4
Food seeking constrained by brief footshock	0.6	0.8	1.1	-1.0	-1.1	0.1	-1.0
Seeking ratio, punishment vs. effort	0.3	0.3	0.5	-0.6	-0.7	-0.1	-0.6
Run reversals in cocaine runway, females	1.1	1.1	1.6	1.3	0.8	-0.8	1.3
Run reversals in cocaine runway, males	0.5	0.5	1.1	-0.8	-1.0	-0.1	-0.2
Latency to leave start box in cocaine runway	0.7	0.8	1.7	-0.8	0.8	-1.3	0.3
Latency to leave start box in cocaine runway, F	0.4	0.4	0.7	0.2	0.8	-0.8	0.6
Latency to leave start box in cocaine runway, M	1.1	1.0	2.6	-1.6	0.2	-1.2	-0.1
Cd content in liver	0.4	0.5	0.7	-0.7	0.7	-0.8	0.4
Co content in liver	0.1	0.1	0.4	-0.3	-0.2	0.2	-0.6
Cu content in liver	1.3	1.6	4.6	2.1	0.7	0.8	0.9
Fe content in liver	0.1	0.1	0.2	-0.2	0.2	0.3	-0.5
K content in liver	0.3	0.3	0.6	0.7	0.0	0.7	0.0
Mg content in liver	0.4	0.4	1.0	0.8	-0.0	1.0	-0.2
Mn content in liver	0.3	0.3	0.8	-0.2	0.3	-0.9	0.7
Na content in liver	0.9	1.0	2.7	1.7	0.6	0.6	0.6
Rb content in liver	0.4	0.5	1.1	0.0	-0.7	1.1	-0.6
Se content in liver	1.4	1.7	3.2	0.9	1.4	-0.9	1.8
Sr content in liver	1.2	1.1	1.9	1.0	1.1	-0.5	1.4
Zn content in liver	0.7	0.8	1.9	1.4	0.7	0.3	0.9