# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | gene expression | ENSRNOG00000024905 | 0.3862 | 0.1620 | 0.0e+00 | 0.337 | 0.323 | 0.314 | 0.315 | 9.7e-19 | 7.5e-18 | 2.5e-17 | 2.2e-17 |
2 | BLA | intron excision ratio | chr6:26027589:26028118 | 0.0770 | 0.0630 | 4.9e-04 | 0.060 | 0.058 | 0.051 | 0.064 | 3.8e-04 | 4.6e-04 | 9.7e-04 | 2.4e-04 |
3 | BLA | intron excision ratio | chr6:26027589:26028390 | 0.2400 | 0.1300 | 1.5e-13 | 0.210 | 0.205 | 0.196 | 0.209 | 1.8e-11 | 3.1e-11 | 9.5e-11 | 2.0e-11 |
4 | BLA | intron excision ratio | chr6:26028389:26030800 | 0.0980 | 0.0940 | 8.8e-04 | 0.033 | 0.029 | 0.053 | 0.041 | 6.7e-03 | 1.1e-02 | 8.3e-04 | 3.0e-03 |
5 | BLA | mRNA stability | ENSRNOG00000024905 | 0.7000 | 0.1200 | 0.0e+00 | 0.324 | 0.344 | 0.342 | 0.345 | 6.6e-18 | 3.6e-19 | 5.2e-19 | 3.4e-19 |
6 | Brain | gene expression | ENSRNOG00000024905 | 0.0980 | 0.0610 | 2.4e-11 | 0.115 | 0.124 | 0.103 | 0.118 | 8.4e-11 | 1.4e-11 | 9.2e-10 | 4.5e-11 |
7 | Brain | intron excision ratio | chr6:26027589:26028118 | 0.1585 | 0.0938 | 7.1e-14 | 0.151 | 0.153 | 0.124 | 0.149 | 7.3e-14 | 4.8e-14 | 1.5e-11 | 1.0e-13 |
8 | Brain | intron excision ratio | chr6:26027589:26028390 | 0.1394 | 0.0793 | 0.0e+00 | 0.183 | 0.189 | 0.178 | 0.190 | 1.0e-16 | 2.7e-17 | 3.1e-16 | 2.4e-17 |
9 | Brain | intron excision ratio | chr6:26028389:26030800 | 0.0768 | 0.0500 | 2.6e-09 | 0.095 | 0.094 | 0.098 | 0.096 | 3.7e-09 | 5.4e-09 | 2.2e-09 | 3.1e-09 |
10 | Brain | intron excision ratio | chr6:26032414:26034251 | 0.0398 | 0.0306 | 6.6e-05 | 0.045 | 0.047 | 0.045 | 0.046 | 4.8e-05 | 3.1e-05 | 5.3e-05 | 4.4e-05 |
11 | Brain | intron excision ratio | chr6:26032414:26034307 | 0.0383 | 0.0296 | 9.6e-05 | 0.042 | 0.045 | 0.043 | 0.043 | 8.1e-05 | 4.7e-05 | 7.7e-05 | 6.6e-05 |
12 | Brain | mRNA stability | ENSRNOG00000024905 | 0.3284 | 0.1574 | 0.0e+00 | 0.267 | 0.294 | 0.291 | 0.282 | 9.1e-25 | 1.8e-27 | 3.5e-27 | 2.9e-26 |
13 | Eye | alternative polyA | ENSRNOT00000116224 | 0.4524 | 0.2466 | 6.2e-03 | 0.091 | 0.073 | 0.065 | 0.059 | 1.7e-02 | 3.0e-02 | 3.8e-02 | 4.5e-02 |
14 | IL | gene expression | ENSRNOG00000024905 | 0.3300 | 0.1640 | 1.6e-07 | 0.228 | 0.232 | 0.186 | 0.224 | 3.4e-06 | 2.7e-06 | 3.1e-05 | 4.2e-06 |
15 | IL | intron excision ratio | chr6:26027589:26028118 | 0.2680 | 0.1520 | 3.6e-06 | 0.183 | 0.169 | 0.166 | 0.175 | 3.7e-05 | 7.2e-05 | 8.4e-05 | 5.6e-05 |
16 | IL | intron excision ratio | chr6:26027589:26028390 | 0.3900 | 0.1860 | 9.7e-09 | 0.277 | 0.249 | 0.251 | 0.271 | 2.2e-07 | 1.1e-06 | 9.6e-07 | 3.3e-07 |
17 | IL | mRNA stability | ENSRNOG00000024905 | 0.4200 | 0.2220 | 2.3e-09 | 0.314 | 0.341 | 0.321 | 0.326 | 2.7e-08 | 5.0e-09 | 1.7e-08 | 1.3e-08 |
18 | LHb | gene expression | ENSRNOG00000024905 | 0.1341 | 0.1167 | 7.4e-03 | 0.075 | 0.055 | 0.073 | 0.081 | 7.8e-03 | 2.0e-02 | 8.2e-03 | 5.7e-03 |
19 | LHb | intron excision ratio | chr6:26027589:26028118 | 0.3520 | 0.1830 | 3.0e-08 | 0.308 | 0.259 | 0.276 | 0.271 | 4.6e-08 | 7.4e-07 | 2.9e-07 | 3.7e-07 |
20 | LHb | intron excision ratio | chr6:26027589:26028390 | 0.6610 | 0.2540 | 5.9e-12 | 0.374 | 0.383 | 0.367 | 0.360 | 7.9e-10 | 4.4e-10 | 1.2e-09 | 2.0e-09 |
21 | LHb | intron excision ratio | chr6:26028389:26030800 | 0.1440 | 0.1080 | 1.4e-03 | 0.122 | 0.115 | 0.160 | 0.134 | 8.0e-04 | 1.2e-03 | 1.3e-04 | 4.5e-04 |
22 | LHb | mRNA stability | ENSRNOG00000024905 | 0.3510 | 0.1730 | 4.9e-08 | 0.318 | 0.293 | 0.273 | 0.304 | 2.5e-08 | 1.1e-07 | 3.3e-07 | 5.8e-08 |
23 | NAcc | gene expression | ENSRNOG00000024905 | 0.0450 | 0.0360 | 3.5e-04 | 0.023 | 0.023 | 0.019 | 0.019 | 7.6e-03 | 7.1e-03 | 1.3e-02 | 1.4e-02 |
24 | NAcc | intron excision ratio | chr6:26027589:26028118 | 0.0404 | 0.0329 | 6.8e-04 | 0.028 | 0.027 | 0.026 | 0.022 | 3.6e-03 | 3.9e-03 | 4.7e-03 | 8.6e-03 |
25 | NAcc | intron excision ratio | chr6:26027589:26028390 | 0.0372 | 0.0313 | 1.4e-03 | 0.030 | 0.036 | 0.025 | 0.030 | 2.5e-03 | 1.1e-03 | 5.4e-03 | 2.7e-03 |
26 | NAcc | mRNA stability | ENSRNOG00000024905 | 0.0710 | 0.0553 | 1.3e-05 | 0.069 | 0.065 | 0.063 | 0.063 | 7.6e-06 | 1.5e-05 | 1.9e-05 | 1.8e-05 |
27 | OFC | gene expression | ENSRNOG00000024905 | 0.1215 | 0.0989 | 5.2e-03 | 0.107 | 0.095 | 0.100 | 0.098 | 1.7e-03 | 3.0e-03 | 2.4e-03 | 2.5e-03 |
28 | OFC | intron excision ratio | chr6:26027589:26028118 | 0.2361 | 0.1928 | 3.4e-03 | 0.119 | 0.076 | 0.065 | 0.100 | 9.5e-04 | 7.4e-03 | 1.3e-02 | 2.3e-03 |
29 | OFC | intron excision ratio | chr6:26027589:26028390 | 0.3479 | 0.3417 | 1.2e-04 | 0.091 | 0.065 | 0.030 | 0.100 | 3.6e-03 | 1.2e-02 | 6.6e-02 | 2.3e-03 |
30 | OFC | mRNA stability | ENSRNOG00000024905 | 0.2890 | 0.1530 | 1.8e-07 | 0.289 | 0.256 | 0.256 | 0.261 | 1.4e-07 | 8.8e-07 | 8.8e-07 | 6.4e-07 |
31 | PL | gene expression | ENSRNOG00000024905 | 0.1750 | 0.1071 | 1.8e-14 | 0.182 | 0.191 | 0.191 | 0.193 | 7.7e-14 | 1.7e-14 | 1.7e-14 | 1.2e-14 |
32 | PL | intron excision ratio | chr6:26027589:26028118 | 0.2589 | 0.1399 | 4.7e-15 | 0.194 | 0.188 | 0.189 | 0.185 | 9.8e-15 | 3.2e-14 | 2.7e-14 | 4.9e-14 |
33 | PL | intron excision ratio | chr6:26027589:26028390 | 0.2752 | 0.1379 | 0.0e+00 | 0.262 | 0.265 | 0.261 | 0.261 | 5.2e-20 | 3.1e-20 | 6.8e-20 | 6.2e-20 |
34 | PL | intron excision ratio | chr6:26028524:26030800 | 0.0510 | 0.0412 | 2.5e-04 | 0.049 | 0.049 | 0.024 | 0.050 | 1.2e-04 | 1.4e-04 | 6.0e-03 | 1.0e-04 |
35 | PL | mRNA stability | ENSRNOG00000024905 | 0.4456 | 0.2210 | 0.0e+00 | 0.399 | 0.407 | 0.407 | 0.413 | 3.3e-32 | 4.8e-33 | 5.3e-33 | 1.2e-33 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 |
---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retroperitoneal fat weight | 28.4 | 94.1 | 102.7 | 10.1 | 8.9 | -9.7 | 9.2 | 9.2 | 9.9 | 9.7 | -9.9 | 9.8 | -10.0 | 10.0 | 9.5 | -10.0 | 10.0 | 9.2 | -10.0 | 9.9 | 9.6 | 9.6 | -9.8 | 9.8 | 10.0 | 9.9 | 10.1 | -10.0 | 9.7 | 10.1 | 7.8 | -9.0 | 10.0 | 9.6 | 9.7 | -9.9 | -9.6 | 9.7 |
Epididymis fat weight | 15.4 | 36.0 | 40.5 | 6.4 | 5.5 | -5.8 | 6.1 | 5.6 | 6.1 | 5.9 | -6.0 | 6.0 | -6.2 | 6.2 | 5.8 | -6.2 | 6.2 | 5.4 | -6.1 | 6.1 | 5.8 | 5.7 | -6.0 | 6.2 | 6.3 | 6.2 | 6.2 | -6.2 | 5.8 | 6.3 | 5.3 | -5.9 | 6.1 | 6.0 | 5.8 | -6.1 | -5.9 | 5.9 |
Food seeking constrained by brief footshock | 13.1 | 15.9 | 20.3 | -4.4 | -3.1 | 3.6 | -4.2 | -3.3 | -4.3 | -4.3 | 3.9 | -3.8 | 4.2 | -4.2 | -4.1 | 4.1 | -4.2 | -3.6 | 4.1 | -3.9 | -3.6 | -4.2 | 3.8 | -3.9 | -4.5 | -4.0 | -4.5 | 4.2 | -3.6 | -4.5 | -3.3 | 3.6 | -4.1 | -3.9 | -3.6 | 4.3 | 4.2 | -3.7 |
Parametrial fat weight | 9.2 | 18.0 | 19.6 | 4.3 | 3.8 | -4.3 | 4.4 | 4.0 | 4.2 | 4.1 | -4.3 | 4.2 | -4.3 | 4.3 | 4.0 | -4.3 | 4.3 | 4.2 | -4.4 | 4.4 | 4.2 | 4.2 | -4.4 | 4.4 | 4.4 | 4.4 | 4.4 | -4.4 | 4.1 | 4.4 | 3.7 | -4.1 | 4.4 | 4.1 | 4.1 | -4.3 | -4.2 | 4.2 |
Total sessions with >9 infusions | 6.9 | 7.5 | 8.6 | -2.8 | -2.3 | 2.9 | -2.6 | -2.5 | -2.8 | -2.8 | 2.8 | -2.7 | 2.8 | -2.8 | -2.7 | 2.8 | -2.8 | -2.7 | 2.9 | -2.8 | -2.9 | -2.8 | 2.8 | -2.6 | -2.8 | -2.8 | -2.7 | 2.8 | -2.9 | -2.8 | -2.1 | 2.4 | -2.9 | -2.6 | -2.9 | 2.8 | 2.8 | -2.9 |
Short access day 10 total infusions | 6.9 | 7.6 | 9.3 | -2.7 | -2.7 | 3.1 | -2.6 | -2.7 | -2.7 | -2.7 | 2.9 | -2.9 | 2.7 | -2.7 | -2.7 | 2.6 | -2.8 | -2.9 | 2.8 | -2.8 | -2.8 | -3.0 | 2.8 | -2.7 | -2.7 | -2.7 | -2.7 | 2.7 | -3.0 | -2.7 | -2.0 | 2.4 | -2.8 | -2.7 | -3.0 | 2.7 | 3.0 | -2.9 |
Short access day 1 locomotion | 6.9 | 7.3 | 11.2 | -2.3 | -2.9 | 2.7 | -3.3 | -3.0 | -2.4 | -2.2 | 2.7 | -2.8 | 2.6 | -2.7 | -2.4 | 2.6 | -2.7 | -2.8 | 2.5 | -2.8 | -2.8 | -2.4 | 2.8 | -2.8 | -2.3 | -2.8 | -2.3 | 2.7 | -2.9 | -2.3 | -3.3 | 3.2 | -2.5 | -2.7 | -2.9 | 2.5 | 2.4 | -2.8 |
Liver weight, right | 6.5 | 10.7 | 14.7 | 3.1 | 3.5 | -3.2 | 3.8 | 3.5 | 3.0 | 2.6 | -3.2 | 3.4 | -3.3 | 3.3 | 2.7 | -3.1 | 3.3 | 3.5 | -3.0 | 3.4 | 3.2 | 3.1 | -3.4 | 3.7 | 3.1 | 3.5 | 2.9 | -3.3 | 3.2 | 3.1 | 3.7 | -3.8 | 3.1 | 3.3 | 3.2 | -3.0 | -3.2 | 3.2 |
Lifetime Intake | 6.2 | 6.9 | 8.3 | -2.6 | -2.3 | 2.8 | -2.6 | -2.5 | -2.6 | -2.5 | 2.8 | -2.7 | 2.6 | -2.6 | -2.5 | 2.5 | -2.6 | -2.6 | 2.6 | -2.6 | -2.7 | -2.8 | 2.6 | -2.5 | -2.6 | -2.6 | -2.6 | 2.6 | -2.9 | -2.6 | -2.1 | 2.4 | -2.6 | -2.5 | -2.9 | 2.6 | 2.9 | -2.8 |
One hour access (shock baseline) | 6.2 | 7.2 | 9.2 | -2.8 | -2.4 | 2.8 | -2.5 | -2.6 | -2.7 | -2.8 | 2.8 | -2.8 | 2.6 | -2.6 | -2.8 | 2.6 | -2.6 | -2.6 | 2.7 | -2.6 | -2.8 | -3.0 | 2.6 | -2.4 | -2.8 | -2.5 | -2.7 | 2.6 | -2.9 | -2.8 | -2.0 | 2.2 | -2.7 | -2.6 | -2.9 | 2.7 | 3.0 | -2.8 |
Progressive ratio test 1 inactive lever presses | 6.0 | 6.4 | 7.8 | -2.4 | -2.6 | 2.8 | -2.8 | -2.5 | -2.4 | -2.2 | 2.7 | -2.6 | 2.5 | -2.5 | -2.3 | 2.6 | -2.5 | -2.5 | 2.4 | -2.6 | -2.7 | -2.4 | 2.6 | -2.6 | -2.4 | -2.6 | -2.4 | 2.5 | -2.8 | -2.4 | -2.6 | 2.6 | -2.4 | -2.5 | -2.8 | 2.4 | 2.5 | -2.7 |
Short access day 1 total infusions | 5.6 | 5.9 | 8.2 | -2.3 | -2.1 | 2.6 | -2.9 | -2.4 | -2.2 | -2.1 | 2.5 | -2.4 | 2.4 | -2.4 | -2.0 | 2.3 | -2.4 | -2.5 | 2.4 | -2.5 | -2.5 | -2.6 | 2.5 | -2.6 | -2.3 | -2.6 | -2.3 | 2.5 | -2.6 | -2.3 | -2.5 | 2.6 | -2.4 | -2.3 | -2.6 | 2.3 | 2.5 | -2.6 |
Short access total infusions | 5.6 | 6.2 | 7.7 | -2.4 | -2.2 | 2.8 | -2.4 | -2.4 | -2.4 | -2.4 | 2.6 | -2.6 | 2.5 | -2.5 | -2.3 | 2.4 | -2.5 | -2.6 | 2.6 | -2.6 | -2.5 | -2.6 | 2.6 | -2.4 | -2.4 | -2.5 | -2.4 | 2.5 | -2.8 | -2.4 | -2.0 | 2.3 | -2.6 | -2.4 | -2.8 | 2.5 | 2.6 | -2.7 |
Intermittent access total infusions | 5.3 | 5.9 | 7.2 | -2.5 | -2.2 | 2.6 | -2.3 | -2.3 | -2.4 | -2.4 | 2.6 | -2.5 | 2.4 | -2.4 | -2.4 | 2.4 | -2.4 | -2.4 | 2.4 | -2.4 | -2.5 | -2.6 | 2.4 | -2.3 | -2.5 | -2.3 | -2.4 | 2.4 | -2.7 | -2.5 | -1.9 | 2.1 | -2.4 | -2.4 | -2.7 | 2.4 | 2.7 | -2.6 |
Co content in liver | 5.2 | 6.1 | 8.4 | -2.4 | -2.9 | 2.6 | -1.9 | -2.8 | -2.4 | -2.3 | 2.6 | -2.7 | 2.5 | -2.5 | -2.4 | 2.4 | -2.5 | -2.7 | 2.4 | -2.5 | -2.6 | -2.1 | 2.5 | -2.5 | -2.4 | -2.5 | -2.3 | 2.5 | -2.5 | -2.4 | -2.1 | 2.3 | -2.4 | -2.5 | -2.5 | 2.4 | 2.2 | -2.5 |
Conditioned reinforcement - inactives | 5.1 | 5.8 | 6.8 | -2.5 | -1.7 | 2.6 | -2.6 | -2.0 | -2.4 | -2.4 | 2.6 | -2.3 | 2.4 | -2.4 | -2.2 | 2.5 | -2.4 | -2.2 | 2.4 | -2.4 | -2.5 | -2.5 | 2.3 | -2.4 | -2.5 | -2.4 | -2.6 | 2.4 | -2.6 | -2.5 | -1.8 | 2.2 | -2.4 | -2.3 | -2.6 | 2.4 | 2.6 | -2.6 |
Intraocular pressure | 5.0 | 7.1 | 9.6 | 2.6 | 3.0 | -2.7 | 2.7 | 3.1 | 2.5 | 2.2 | -2.7 | 2.9 | -2.6 | 2.7 | 2.4 | -2.4 | 2.7 | 2.7 | -2.5 | 2.8 | 2.8 | 2.4 | -2.8 | 2.8 | 2.5 | 2.8 | 2.5 | -2.7 | 2.8 | 2.5 | 2.9 | -2.9 | 2.5 | 2.8 | 2.8 | -2.5 | -2.5 | 2.7 |
Time to tail flick, vehicle, after self-admin | 5.0 | 5.3 | 7.8 | 2.8 | 1.8 | -1.9 | 2.4 | 1.8 | 2.6 | 2.5 | -2.2 | 2.1 | -2.6 | 2.5 | 2.3 | -2.3 | 2.5 | 1.6 | -2.3 | 2.3 | 1.9 | 2.3 | -2.1 | 2.5 | 2.8 | 2.4 | 2.8 | -2.6 | 1.8 | 2.7 | 2.0 | -2.2 | 2.3 | 2.4 | 1.8 | -2.5 | -2.1 | 1.9 |
Heart weight | 4.8 | 6.8 | 11.0 | 2.6 | 2.6 | -2.6 | 3.2 | 2.7 | 2.4 | 2.0 | -2.5 | 2.6 | -2.7 | 2.8 | 1.9 | -2.4 | 2.7 | 2.5 | -2.4 | 2.8 | 2.4 | 2.1 | -2.7 | 3.3 | 2.6 | 3.0 | 2.6 | -2.8 | 2.4 | 2.7 | 3.2 | -3.3 | 2.4 | 2.6 | 2.4 | -2.4 | -2.2 | 2.4 |
Conditioned reinforcement - actives | 4.5 | 4.4 | 6.3 | -1.9 | -1.8 | 2.2 | -2.0 | -2.1 | -2.0 | -2.1 | 2.2 | -2.2 | 2.0 | -2.0 | -2.1 | 2.2 | -2.0 | -2.1 | 2.2 | -2.1 | -2.2 | -2.4 | 2.2 | -1.8 | -1.9 | -2.0 | -1.9 | 2.0 | -2.5 | -1.9 | -1.5 | 1.8 | -2.2 | -1.9 | -2.5 | 2.0 | 2.5 | -2.4 |
Intermittent access day 15 total infusions | 4.4 | 4.9 | 6.6 | -2.3 | -1.9 | 2.3 | -2.2 | -2.1 | -2.2 | -2.2 | 2.3 | -2.2 | 2.2 | -2.2 | -2.2 | 2.2 | -2.2 | -2.0 | 2.2 | -2.2 | -2.3 | -2.4 | 2.2 | -2.1 | -2.3 | -2.2 | -2.3 | 2.2 | -2.4 | -2.3 | -1.8 | 2.0 | -2.2 | -2.2 | -2.4 | 2.2 | 2.6 | -2.3 |
Intermittent access day 1 total infusions | 4.3 | 4.9 | 5.8 | -2.1 | -2.4 | 2.2 | -2.4 | -2.4 | -2.0 | -1.8 | 2.3 | -2.3 | 2.2 | -2.2 | -1.9 | 2.0 | -2.2 | -2.2 | 2.1 | -2.3 | -2.0 | -2.3 | 2.3 | -2.4 | -2.1 | -2.3 | -2.1 | 2.2 | -2.3 | -2.1 | -2.3 | 2.4 | -2.1 | -2.3 | -2.3 | 2.0 | 2.2 | -2.2 |
Conditioned locomotion | 3.9 | 4.7 | 6.1 | -2.0 | -2.3 | 2.3 | -2.2 | -2.4 | -2.1 | -2.0 | 2.2 | -2.3 | 2.1 | -2.1 | -2.1 | 2.1 | -2.1 | -2.5 | 2.1 | -2.2 | -2.3 | -2.1 | 2.2 | -2.1 | -2.0 | -2.1 | -2.1 | 2.1 | -2.3 | -2.0 | -2.1 | 2.2 | -2.1 | -2.2 | -2.3 | 2.1 | 2.0 | -2.3 |
Intermittent access terminal intake (last 3 days) | 3.9 | 4.2 | 5.1 | -2.1 | -2.0 | 2.2 | -2.0 | -2.1 | -2.0 | -2.0 | 2.2 | -2.1 | 2.0 | -2.0 | -2.1 | 1.9 | -2.0 | -2.0 | 2.0 | -2.0 | -2.1 | -2.1 | 2.0 | -1.9 | -2.1 | -2.0 | -2.1 | 2.0 | -2.3 | -2.1 | -1.8 | 1.9 | -2.0 | -2.0 | -2.3 | 2.0 | 2.3 | -2.2 |
Change in fecal boli incidents, locomotor task | 3.8 | 3.6 | 6.1 | 1.6 | 2.1 | -1.9 | 2.5 | 1.9 | 1.8 | 1.6 | -1.8 | 2.0 | -1.9 | 1.9 | 1.8 | -1.8 | 1.9 | 1.8 | -1.9 | 2.0 | 1.8 | 1.8 | -2.0 | 2.0 | 1.8 | 2.0 | 1.8 | -1.9 | 1.8 | 1.8 | 2.4 | -2.3 | 1.9 | 2.0 | 1.8 | -1.8 | -1.8 | 1.8 |
Short access day 1 total inactive lever presses | 3.6 | 4.0 | 7.5 | -1.6 | -1.8 | 2.2 | -2.7 | -1.9 | -1.7 | -1.6 | 2.0 | -2.0 | 1.9 | -1.9 | -1.6 | 2.0 | -1.9 | -1.9 | 2.1 | -2.1 | -2.1 | -2.3 | 2.2 | -2.1 | -1.6 | -2.0 | -1.6 | 1.9 | -2.2 | -1.6 | -2.2 | 2.3 | -2.1 | -1.7 | -2.2 | 1.7 | 2.4 | -2.2 |
Compulsive drug intake | 3.6 | 3.6 | 5.1 | 2.1 | 2.3 | -1.8 | 1.5 | 2.0 | 2.0 | 2.0 | -2.1 | 2.1 | -1.9 | 1.9 | 2.1 | -1.7 | 1.8 | 1.8 | -1.7 | 1.7 | 1.8 | 1.7 | -1.7 | 1.7 | 2.1 | 1.7 | 2.0 | -1.8 | 2.0 | 2.1 | 1.5 | -1.5 | 1.7 | 2.1 | 2.0 | -2.0 | -1.8 | 1.9 |
Conditioned locomotion | 3.5 | 4.2 | 5.2 | -1.9 | -2.0 | 2.2 | -1.5 | -2.2 | -2.1 | -2.2 | 2.2 | -2.2 | 2.0 | -2.0 | -2.2 | 2.2 | -2.0 | -1.9 | 2.1 | -2.0 | -2.1 | -2.2 | 2.1 | -1.8 | -1.9 | -1.9 | -2.0 | 2.0 | -2.3 | -1.9 | -1.3 | 1.6 | -2.1 | -2.1 | -2.3 | 2.1 | 2.3 | -2.2 |
Locomotion in novel chamber post-restriction | 3.4 | 4.0 | 6.5 | 1.9 | 2.5 | -2.2 | 1.2 | 2.3 | 2.0 | 2.0 | -2.1 | 2.2 | -1.9 | 1.9 | 2.2 | -2.1 | 1.9 | 2.1 | -2.1 | 2.0 | 2.1 | 2.0 | -2.1 | 1.7 | 1.9 | 1.9 | 1.8 | -1.9 | 2.2 | 1.9 | 1.2 | -1.6 | 2.1 | 2.1 | 2.2 | -2.0 | -2.0 | 2.1 |
Progressive ratio test 1 active lever presses | 3.3 | 3.4 | 4.4 | -1.8 | -1.7 | 2.1 | -1.8 | -1.8 | -1.8 | -1.7 | 2.0 | -1.9 | 1.8 | -1.8 | -1.7 | 1.9 | -1.8 | -1.8 | 1.8 | -1.9 | -2.0 | -2.0 | 1.9 | -1.8 | -1.8 | -1.9 | -1.8 | 1.8 | -2.1 | -1.8 | -1.4 | 1.7 | -1.8 | -1.7 | -2.1 | 1.8 | 2.0 | -2.1 |
Bone: cortical porosity | 3.3 | 3.6 | 5.2 | -2.0 | -2.3 | 1.7 | -1.5 | -2.1 | -1.9 | -1.9 | 1.9 | -2.1 | 1.9 | -1.9 | -2.0 | 1.9 | -1.9 | -2.1 | 1.9 | -1.9 | -1.8 | -1.8 | 1.9 | -1.9 | -2.0 | -1.9 | -2.0 | 1.9 | -1.7 | -2.0 | -1.5 | 1.7 | -1.9 | -2.1 | -1.7 | 1.9 | 1.8 | -1.7 |
Progressive ratio test 2 inactive lever presses | 3.2 | 3.7 | 4.4 | -2.0 | -1.7 | 2.0 | -2.1 | -1.8 | -1.9 | -1.8 | 2.0 | -1.8 | 2.0 | -2.0 | -1.8 | 2.0 | -1.9 | -1.7 | 1.8 | -1.9 | -1.9 | -1.9 | 1.9 | -2.0 | -2.0 | -2.0 | -2.0 | 2.0 | -2.0 | -2.0 | -1.8 | 1.9 | -1.8 | -1.9 | -2.0 | 1.9 | 2.1 | -2.0 |
Bone: apparent density | 3.0 | 5.0 | 7.5 | -2.2 | -2.1 | 2.1 | -2.7 | -2.2 | -2.1 | -1.9 | 2.2 | -2.3 | 2.2 | -2.3 | -1.9 | 2.2 | -2.2 | -2.1 | 2.2 | -2.3 | -2.2 | -2.3 | 2.3 | -2.5 | -2.2 | -2.4 | -2.2 | 2.3 | -2.2 | -2.2 | -2.4 | 2.5 | -2.2 | -2.2 | -2.2 | 2.1 | 2.4 | -2.2 |
Bone: trabecular number | 3.0 | 4.7 | 6.0 | -2.3 | -1.8 | 2.1 | -2.4 | -1.9 | -2.1 | -2.0 | 2.2 | -2.1 | 2.2 | -2.3 | -1.9 | 2.1 | -2.2 | -1.9 | 2.1 | -2.2 | -2.2 | -2.5 | 2.1 | -2.4 | -2.3 | -2.3 | -2.3 | 2.3 | -2.2 | -2.3 | -1.8 | 2.1 | -2.1 | -2.1 | -2.2 | 2.2 | 2.4 | -2.1 |
Intermitt. access escalation Index | 2.9 | 2.6 | 4.3 | 1.7 | 2.0 | -1.5 | 1.4 | 1.6 | 1.7 | 1.8 | -1.7 | 1.8 | -1.5 | 1.5 | 1.9 | -1.5 | 1.5 | 1.7 | -1.6 | 1.5 | 1.5 | 2.1 | -1.6 | 1.2 | 1.7 | 1.4 | 1.6 | -1.5 | 1.7 | 1.7 | 1.0 | -1.2 | 1.6 | 1.6 | 1.7 | -1.7 | -1.8 | 1.6 |
Soleus weight | 2.7 | 7.9 | 12.0 | -2.6 | -2.9 | 2.6 | -3.5 | -2.9 | -2.6 | -2.4 | 2.6 | -2.9 | 2.8 | -2.8 | -2.5 | 2.9 | -2.8 | -2.7 | 2.9 | -3.0 | -2.5 | -3.4 | 3.0 | -3.0 | -2.6 | -3.0 | -2.4 | 2.9 | -2.5 | -2.6 | -3.0 | 3.1 | -2.8 | -2.7 | -2.5 | 2.7 | 3.0 | -2.6 |
Pavlov. Cond. intertrial magazine entries | 2.7 | 3.5 | 3.9 | 1.7 | 1.9 | -1.9 | 1.9 | 2.0 | 1.8 | 1.7 | -1.9 | 2.0 | -1.9 | 1.9 | 1.8 | -1.8 | 1.9 | 1.9 | -1.8 | 1.9 | 2.0 | 1.6 | -1.9 | 1.9 | 1.7 | 1.9 | 1.9 | -1.9 | 2.0 | 1.7 | 2.0 | -2.0 | 1.8 | 1.9 | 2.0 | -1.8 | -1.7 | 2.0 |
Progressive ratio test 1 breakpoint | 2.6 | 2.7 | 3.4 | -1.6 | -1.5 | 1.8 | -1.7 | -1.6 | -1.5 | -1.5 | 1.7 | -1.7 | 1.6 | -1.6 | -1.5 | 1.6 | -1.6 | -1.6 | 1.6 | -1.7 | -1.8 | -1.8 | 1.7 | -1.6 | -1.6 | -1.7 | -1.5 | 1.6 | -1.8 | -1.6 | -1.4 | 1.6 | -1.6 | -1.5 | -1.8 | 1.6 | 1.8 | -1.8 |
Bone: cortical porosity | 2.6 | 2.8 | 4.0 | -1.7 | -2.0 | 1.5 | -1.2 | -1.9 | -1.7 | -1.7 | 1.6 | -1.8 | 1.7 | -1.7 | -1.7 | 1.7 | -1.7 | -1.9 | 1.7 | -1.7 | -1.6 | -1.8 | 1.7 | -1.6 | -1.7 | -1.7 | -1.7 | 1.7 | -1.6 | -1.7 | -1.2 | 1.4 | -1.6 | -1.8 | -1.6 | 1.7 | 1.7 | -1.6 |
BMI with tail | 2.5 | 7.9 | 11.3 | 3.0 | 3.0 | -2.7 | 2.0 | 2.9 | 3.1 | 3.3 | -2.8 | 2.9 | -2.8 | 2.8 | 3.4 | -3.1 | 2.8 | 2.9 | -3.0 | 2.8 | 2.8 | 2.9 | -2.8 | 2.2 | 3.0 | 2.6 | 2.8 | -2.8 | 2.7 | 2.9 | 1.7 | -2.0 | 3.1 | 2.9 | 2.7 | -3.0 | -3.1 | 2.8 |
One hour access (0.3 mA shock) | 2.5 | 2.9 | 5.0 | -1.6 | -1.1 | 1.9 | -2.1 | -1.5 | -1.6 | -1.6 | 1.7 | -1.6 | 1.6 | -1.6 | -1.6 | 1.7 | -1.7 | -1.6 | 1.9 | -1.8 | -1.8 | -2.2 | 1.8 | -1.6 | -1.6 | -1.7 | -1.5 | 1.6 | -1.7 | -1.6 | -1.5 | 1.6 | -1.9 | -1.4 | -1.7 | 1.6 | 2.2 | -1.8 |
Number of responses in last shaping day | 2.5 | 2.5 | 3.3 | -1.8 | -1.5 | 1.8 | -1.0 | -1.7 | -1.7 | -1.7 | 1.7 | -1.6 | 1.6 | -1.6 | -1.7 | 1.5 | -1.6 | -1.5 | 1.5 | -1.5 | -1.7 | -1.6 | 1.5 | -1.5 | -1.8 | -1.5 | -1.7 | 1.6 | -1.7 | -1.8 | -0.8 | 1.0 | -1.5 | -1.6 | -1.7 | 1.7 | 1.7 | -1.6 |
Fecal boli incidents, locomotor time 1 | 2.5 | 2.7 | 3.9 | -1.9 | -1.3 | 1.6 | -1.2 | -1.4 | -1.8 | -2.0 | 1.7 | -1.6 | 1.7 | -1.7 | -1.9 | 1.8 | -1.7 | -1.3 | 1.8 | -1.6 | -1.7 | -1.9 | 1.5 | -1.4 | -1.8 | -1.5 | -1.8 | 1.7 | -1.6 | -1.8 | -0.8 | 1.1 | -1.8 | -1.6 | -1.6 | 1.8 | 1.9 | -1.6 |
Reaction time false alarm rate | 2.4 | 3.5 | 5.2 | 1.6 | 2.2 | -2.0 | 1.0 | 2.2 | 1.8 | 2.1 | -2.0 | 2.1 | -1.7 | 1.6 | 2.2 | -1.9 | 1.7 | 2.0 | -2.0 | 1.8 | 2.2 | 2.2 | -1.9 | 1.2 | 1.6 | 1.5 | 1.7 | -1.6 | 2.2 | 1.6 | 0.8 | -1.2 | 2.0 | 1.8 | 2.2 | -1.8 | -2.3 | 2.1 |
Intermittent access day 1 locomotion | 2.4 | 2.5 | 3.7 | -1.5 | -1.4 | 1.5 | -1.9 | -1.3 | -1.5 | -1.5 | 1.6 | -1.5 | 1.6 | -1.6 | -1.5 | 1.5 | -1.6 | -1.4 | 1.6 | -1.6 | -1.5 | -1.6 | 1.6 | -1.6 | -1.5 | -1.6 | -1.6 | 1.6 | -1.6 | -1.5 | -1.6 | 1.6 | -1.6 | -1.5 | -1.6 | 1.5 | 1.6 | -1.6 |
Short access total locomotion | 2.4 | 2.5 | 3.1 | -1.4 | -1.6 | 1.7 | -1.4 | -1.6 | -1.6 | -1.7 | 1.7 | -1.7 | 1.6 | -1.6 | -1.7 | 1.6 | -1.6 | -1.5 | 1.6 | -1.6 | -1.7 | -1.5 | 1.6 | -1.3 | -1.4 | -1.5 | -1.5 | 1.6 | -1.8 | -1.4 | -1.3 | 1.4 | -1.6 | -1.5 | -1.8 | 1.6 | 1.6 | -1.7 |
Extensor digitorum longus weight | 2.3 | 9.2 | 20.1 | -2.9 | -3.0 | 2.6 | -4.5 | -2.9 | -2.7 | -2.3 | 2.7 | -2.9 | 3.0 | -3.1 | -2.5 | 2.9 | -3.1 | -2.7 | 3.0 | -3.2 | -2.6 | -3.5 | 3.2 | -3.5 | -2.9 | -3.3 | -2.7 | 3.1 | -2.6 | -2.9 | -4.0 | 3.9 | -2.9 | -2.9 | -2.6 | 2.7 | 3.2 | -2.6 |
Cocaine response before conditioning | 2.3 | 2.8 | 3.4 | -1.6 | -1.9 | 1.7 | -1.8 | -1.8 | -1.7 | -1.6 | 1.7 | -1.8 | 1.7 | -1.7 | -1.8 | 1.6 | -1.7 | -1.8 | 1.6 | -1.7 | -1.7 | -1.5 | 1.7 | -1.6 | -1.6 | -1.7 | -1.5 | 1.7 | -1.6 | -1.6 | -1.8 | 1.7 | -1.6 | -1.7 | -1.6 | 1.7 | 1.5 | -1.7 |
Delay disc. indifference point, 24s delay | 2.3 | 2.2 | 2.8 | -1.6 | -1.5 | 1.5 | -0.7 | -1.5 | -1.6 | -1.7 | 1.6 | -1.6 | 1.5 | -1.5 | -1.7 | 1.6 | -1.5 | -1.6 | 1.6 | -1.5 | -1.6 | -1.5 | 1.5 | -1.3 | -1.6 | -1.4 | -1.7 | 1.5 | -1.5 | -1.6 | -0.5 | 0.9 | -1.6 | -1.5 | -1.5 | 1.6 | 1.5 | -1.5 |
Body weight | 2.2 | 9.2 | 11.4 | 2.8 | 3.4 | -2.9 | 3.0 | 3.3 | 3.0 | 2.9 | -3.1 | 3.2 | -3.0 | 3.0 | 3.0 | -3.2 | 3.0 | 3.1 | -3.1 | 3.1 | 2.9 | 2.9 | -3.2 | 3.0 | 2.9 | 3.1 | 2.9 | -3.0 | 3.1 | 2.9 | 2.9 | -3.0 | 3.1 | 3.2 | 3.1 | -3.0 | -3.0 | 3.1 |
Intermitt. access day 15 inactive lever presses | 2.2 | 2.5 | 7.5 | -1.4 | -1.7 | 1.4 | -2.5 | -1.6 | -1.2 | -0.7 | 1.5 | -1.4 | 1.5 | -1.6 | -0.8 | 1.3 | -1.5 | -1.4 | 1.1 | -1.6 | -1.3 | -1.2 | 1.5 | -2.3 | -1.4 | -1.9 | -1.4 | 1.6 | -1.5 | -1.4 | -2.7 | 2.3 | -1.1 | -1.7 | -1.5 | 1.2 | 1.1 | -1.4 |
Progressive ratio test 2 breakpoint | 2.2 | 2.4 | 3.6 | -1.8 | -1.1 | 1.8 | -0.9 | -1.5 | -1.7 | -1.8 | 1.7 | -1.5 | 1.6 | -1.6 | -1.7 | 1.7 | -1.5 | -1.4 | 1.5 | -1.4 | -1.7 | -1.7 | 1.4 | -1.3 | -1.8 | -1.4 | -1.8 | 1.5 | -1.7 | -1.8 | -0.5 | 0.9 | -1.5 | -1.5 | -1.7 | 1.7 | 1.9 | -1.7 |
Stereotopy head waving bouts, day 3 | 2.2 | 2.6 | 3.8 | -1.6 | -1.9 | 1.6 | -1.2 | -1.9 | -1.6 | -1.4 | 1.7 | -1.7 | 1.6 | -1.7 | -1.5 | 1.5 | -1.6 | -1.7 | 1.5 | -1.6 | -1.6 | -1.3 | 1.6 | -1.7 | -1.6 | -1.7 | -1.6 | 1.7 | -1.6 | -1.6 | -1.5 | 1.6 | -1.5 | -1.9 | -1.6 | 1.6 | 1.3 | -1.6 |
Pavlov. Cond. intertrial magazine entries | 2.2 | 2.6 | 3.4 | -1.6 | -1.7 | 1.7 | -1.3 | -1.7 | -1.6 | -1.7 | 1.7 | -1.8 | 1.6 | -1.6 | -1.6 | 1.7 | -1.6 | -1.8 | 1.6 | -1.6 | -1.8 | -1.7 | 1.7 | -1.5 | -1.6 | -1.6 | -1.5 | 1.6 | -1.7 | -1.6 | -1.1 | 1.3 | -1.6 | -1.5 | -1.7 | 1.6 | 1.6 | -1.7 |
Progressive ratio test 2 active lever presses | 2.1 | 2.2 | 3.3 | -1.7 | -1.0 | 1.7 | -0.8 | -1.3 | -1.6 | -1.7 | 1.7 | -1.5 | 1.5 | -1.5 | -1.6 | 1.6 | -1.5 | -1.3 | 1.5 | -1.4 | -1.7 | -1.7 | 1.3 | -1.2 | -1.7 | -1.3 | -1.7 | 1.5 | -1.7 | -1.7 | -0.3 | 0.8 | -1.5 | -1.4 | -1.7 | 1.6 | 1.8 | -1.7 |
Latency to leave start box in cocaine runway, M | 2.1 | 2.0 | 3.1 | -1.2 | -1.6 | 1.6 | -1.0 | -1.7 | -1.3 | -1.3 | 1.5 | -1.6 | 1.3 | -1.3 | -1.5 | 1.3 | -1.3 | -1.7 | 1.4 | -1.4 | -1.6 | -1.6 | 1.5 | -1.2 | -1.2 | -1.3 | -1.2 | 1.3 | -1.6 | -1.2 | -0.9 | 1.2 | -1.4 | -1.4 | -1.6 | 1.3 | 1.6 | -1.6 |
Mg content in liver | 2.1 | 2.2 | 3.7 | 1.2 | 1.9 | -1.7 | 1.1 | 1.9 | 1.4 | 1.5 | -1.6 | 1.8 | -1.3 | 1.3 | 1.7 | -1.5 | 1.4 | 1.9 | -1.5 | 1.4 | 1.7 | 1.5 | -1.6 | 1.2 | 1.2 | 1.3 | 1.0 | -1.3 | 1.7 | 1.2 | 1.2 | -1.3 | 1.5 | 1.5 | 1.7 | -1.4 | -1.3 | 1.7 |
Mean time between licks in bursts | 2.0 | 2.7 | 4.5 | 1.6 | 1.6 | -1.6 | 2.1 | 1.6 | 1.5 | 1.3 | -1.6 | 1.6 | -1.7 | 1.7 | 1.4 | -1.6 | 1.7 | 1.3 | -1.6 | 1.8 | 1.5 | 1.8 | -1.7 | 1.9 | 1.6 | 1.8 | 1.5 | -1.7 | 1.5 | 1.6 | 1.9 | -2.0 | 1.6 | 1.6 | 1.5 | -1.5 | -1.8 | 1.6 |
Reaction time num false alarms | 2.0 | 2.7 | 4.4 | 1.4 | 2.1 | -1.9 | 0.4 | 2.0 | 1.6 | 1.9 | -1.8 | 2.0 | -1.4 | 1.4 | 2.0 | -1.7 | 1.4 | 2.0 | -1.7 | 1.5 | 2.0 | 1.9 | -1.7 | 0.8 | 1.4 | 1.2 | 1.4 | -1.3 | 2.0 | 1.4 | 0.4 | -0.8 | 1.7 | 1.6 | 2.0 | -1.6 | -1.9 | 2.0 |
Reaction time num false alarms AUC | 2.0 | 2.8 | 4.2 | 1.4 | 2.0 | -2.0 | 0.6 | 1.9 | 1.7 | 1.9 | -1.8 | 2.0 | -1.4 | 1.4 | 2.0 | -1.7 | 1.5 | 1.9 | -1.8 | 1.5 | 2.0 | 1.9 | -1.7 | 0.9 | 1.4 | 1.3 | 1.5 | -1.4 | 2.0 | 1.4 | 0.5 | -0.8 | 1.8 | 1.6 | 2.0 | -1.6 | -2.0 | 2.0 |
Bone: connectivity density | 2.0 | 3.1 | 8.2 | -1.7 | -1.4 | 1.5 | -2.9 | -1.4 | -1.5 | -1.3 | 1.6 | -1.6 | 1.8 | -1.8 | -1.3 | 1.8 | -1.8 | -1.4 | 1.7 | -1.9 | -1.6 | -1.9 | 1.8 | -2.1 | -1.7 | -1.9 | -1.7 | 1.8 | -1.6 | -1.7 | -2.3 | 2.3 | -1.7 | -1.5 | -1.6 | 1.6 | 1.9 | -1.6 |
Delta distance traveled before/after self-admin | 2.0 | 2.1 | 2.7 | 1.2 | 1.5 | -1.5 | 1.5 | 1.6 | 1.4 | 1.4 | -1.5 | 1.5 | -1.4 | 1.4 | 1.4 | -1.5 | 1.4 | 1.6 | -1.5 | 1.5 | 1.5 | 1.6 | -1.5 | 1.3 | 1.3 | 1.4 | 1.2 | -1.4 | 1.5 | 1.3 | 1.4 | -1.4 | 1.5 | 1.4 | 1.5 | -1.4 | -1.5 | 1.5 |
K content in liver | 2.0 | 2.0 | 3.5 | 1.3 | 1.6 | -1.5 | 1.2 | 1.6 | 1.4 | 1.5 | -1.5 | 1.6 | -1.3 | 1.3 | 1.6 | -1.4 | 1.3 | 1.6 | -1.4 | 1.4 | 1.5 | 1.9 | -1.4 | 1.1 | 1.3 | 1.2 | 1.1 | -1.3 | 1.6 | 1.3 | 1.0 | -1.1 | 1.4 | 1.4 | 1.6 | -1.4 | -1.5 | 1.5 |
Condit. Reinf. active minus inactive responses | 1.9 | 2.1 | 2.7 | 1.5 | 1.7 | -1.4 | 1.3 | 1.5 | 1.5 | 1.5 | -1.4 | 1.5 | -1.5 | 1.4 | 1.6 | -1.4 | 1.4 | 1.4 | -1.4 | 1.4 | 1.4 | 1.4 | -1.4 | 1.3 | 1.5 | 1.4 | 1.6 | -1.4 | 1.4 | 1.5 | 1.3 | -1.3 | 1.4 | 1.6 | 1.4 | -1.5 | -1.5 | 1.4 |
Delay disc. indifference point, 0s delay | 1.8 | 1.9 | 7.2 | 1.3 | 1.3 | -1.2 | 2.6 | 1.4 | 1.1 | 0.7 | -1.1 | 1.2 | -1.3 | 1.4 | 0.9 | -1.2 | 1.3 | 1.0 | -1.2 | 1.5 | 1.1 | 1.1 | -1.4 | 1.6 | 1.2 | 1.6 | 1.0 | -1.4 | 1.2 | 1.2 | 2.7 | -2.2 | 1.2 | 1.3 | 1.2 | -1.1 | -1.1 | 1.1 |
Zn content in liver | 1.8 | 2.0 | 3.1 | 1.2 | 1.8 | -1.6 | 1.5 | 1.7 | 1.3 | 1.2 | -1.5 | 1.7 | -1.3 | 1.3 | 1.3 | -1.4 | 1.4 | 1.6 | -1.4 | 1.5 | 1.5 | 1.7 | -1.6 | 1.4 | 1.2 | 1.4 | 1.0 | -1.3 | 1.5 | 1.2 | 1.3 | -1.5 | 1.4 | 1.3 | 1.5 | -1.3 | -1.4 | 1.6 |
Delay discounting total patch changes 6 sec | 1.7 | 2.6 | 4.3 | 1.5 | 1.4 | -1.8 | 0.7 | 1.6 | 1.8 | 2.1 | -1.7 | 1.7 | -1.5 | 1.5 | 2.0 | -2.0 | 1.6 | 1.7 | -1.8 | 1.5 | 1.8 | 1.6 | -1.6 | 1.0 | 1.5 | 1.3 | 1.7 | -1.5 | 1.8 | 1.6 | 0.5 | -0.8 | 1.9 | 1.6 | 1.8 | -1.8 | -1.7 | 1.8 |
Intermittent access intake day 1-15 change | 1.7 | 1.7 | 2.8 | -1.4 | -1.0 | 1.4 | -1.1 | -1.2 | -1.5 | -1.6 | 1.3 | -1.3 | 1.3 | -1.3 | -1.6 | 1.4 | -1.3 | -1.0 | 1.4 | -1.2 | -1.6 | -1.3 | 1.2 | -0.9 | -1.4 | -1.1 | -1.4 | 1.2 | -1.3 | -1.4 | -0.8 | 0.9 | -1.4 | -1.2 | -1.3 | 1.4 | 1.7 | -1.4 |
Bone: elastic displacement | 1.7 | 2.0 | 3.0 | -1.3 | -1.6 | 1.5 | -1.1 | -1.6 | -1.3 | -1.3 | 1.5 | -1.6 | 1.3 | -1.3 | -1.3 | 1.3 | -1.4 | -1.7 | 1.3 | -1.4 | -1.5 | -1.6 | 1.4 | -1.4 | -1.3 | -1.4 | -1.2 | 1.3 | -1.6 | -1.3 | -0.8 | 1.1 | -1.4 | -1.3 | -1.6 | 1.3 | 1.7 | -1.5 |
Bone: post-yield work | 1.7 | 2.3 | 3.3 | -1.6 | -1.2 | 1.5 | -1.3 | -1.3 | -1.7 | -1.8 | 1.5 | -1.5 | 1.6 | -1.6 | -1.7 | 1.6 | -1.6 | -1.3 | 1.8 | -1.5 | -1.6 | -1.7 | 1.5 | -1.4 | -1.6 | -1.5 | -1.6 | 1.6 | -1.5 | -1.6 | -0.8 | 1.2 | -1.7 | -1.4 | -1.5 | 1.7 | 1.7 | -1.5 |
Condit. Reinf. active minus inactive responses | 1.6 | 2.0 | 5.7 | -1.2 | -1.7 | 1.0 | -2.0 | -1.7 | -1.1 | -0.8 | 1.2 | -1.4 | 1.4 | -1.4 | -1.0 | 1.2 | -1.4 | -1.5 | 1.3 | -1.5 | -1.0 | -1.0 | 1.5 | -1.9 | -1.2 | -1.7 | -1.2 | 1.5 | -1.1 | -1.2 | -2.4 | 2.1 | -1.2 | -1.5 | -1.1 | 1.1 | 1.0 | -1.1 |
Baseline Anxiety | 1.6 | 1.7 | 5.7 | 1.2 | 0.9 | -1.1 | 2.4 | 0.8 | 1.2 | 1.1 | -1.1 | 1.2 | -1.3 | 1.3 | 1.0 | -1.2 | 1.3 | 1.3 | -1.3 | 1.3 | 1.1 | 1.1 | -1.3 | 1.4 | 1.2 | 1.4 | 1.2 | -1.3 | 1.1 | 1.2 | 2.0 | -1.8 | 1.3 | 1.1 | 1.1 | -1.2 | -1.3 | 1.2 |
Locomotion velocity, NPP test | 1.6 | 2.3 | 4.4 | -1.5 | -1.5 | 1.2 | -2.1 | -1.4 | -1.4 | -1.2 | 1.3 | -1.4 | 1.5 | -1.6 | -1.3 | 1.5 | -1.6 | -1.3 | 1.5 | -1.6 | -1.3 | -1.4 | 1.6 | -1.7 | -1.5 | -1.7 | -1.5 | 1.6 | -1.2 | -1.5 | -2.0 | 2.0 | -1.5 | -1.5 | -1.2 | 1.4 | 1.3 | -1.3 |
Active lever presses in extinction session 6 | 1.6 | 1.6 | 2.2 | -1.5 | -0.8 | 1.4 | -1.2 | -1.0 | -1.3 | -1.2 | 1.3 | -1.2 | 1.3 | -1.3 | -1.1 | 1.2 | -1.3 | -1.0 | 1.3 | -1.3 | -1.3 | -1.4 | 1.2 | -1.4 | -1.4 | -1.3 | -1.4 | 1.3 | -1.3 | -1.4 | -0.9 | 1.1 | -1.2 | -1.2 | -1.3 | 1.3 | 1.4 | -1.2 |
Post-drug Anxiety | 1.5 | 1.7 | 2.9 | 1.2 | 1.7 | -1.3 | 1.2 | 1.4 | 1.2 | 1.2 | -1.3 | 1.3 | -1.3 | 1.3 | 1.3 | -1.2 | 1.3 | 1.1 | -1.3 | 1.3 | 1.3 | 0.9 | -1.4 | 1.3 | 1.2 | 1.3 | 1.2 | -1.3 | 1.4 | 1.2 | 1.4 | -1.4 | 1.3 | 1.4 | 1.4 | -1.2 | -1.3 | 1.3 |
Bone volume | 1.5 | 2.5 | 3.5 | -1.6 | -1.4 | 1.4 | -1.9 | -1.5 | -1.5 | -1.4 | 1.5 | -1.6 | 1.6 | -1.6 | -1.4 | 1.5 | -1.6 | -1.4 | 1.5 | -1.6 | -1.5 | -1.7 | 1.6 | -1.7 | -1.6 | -1.7 | -1.7 | 1.6 | -1.5 | -1.6 | -1.6 | 1.6 | -1.5 | -1.6 | -1.5 | 1.5 | 1.7 | -1.5 |
Delta time to tail flick, vehicle, before/after SA | 1.5 | 1.4 | 2.9 | 1.7 | 0.4 | -1.1 | 1.0 | 0.7 | 1.5 | 1.6 | -1.2 | 1.0 | -1.3 | 1.3 | 1.5 | -1.2 | 1.3 | 0.9 | -1.2 | 1.0 | 0.9 | 1.1 | -0.9 | 1.1 | 1.7 | 1.1 | 1.6 | -1.3 | 1.1 | 1.7 | 0.6 | -0.7 | 1.2 | 1.2 | 1.1 | -1.5 | -0.9 | 1.1 |
Delta time to tail flick, test, before/after SA | 1.5 | 1.3 | 2.0 | -1.3 | -1.1 | 1.0 | -0.6 | -1.1 | -1.3 | -1.4 | 1.1 | -1.1 | 1.2 | -1.2 | -1.4 | 1.4 | -1.2 | -0.8 | 1.2 | -1.1 | -1.0 | -1.4 | 1.1 | -0.9 | -1.3 | -1.0 | -1.2 | 1.1 | -1.1 | -1.3 | -0.5 | 0.7 | -1.2 | -1.2 | -1.1 | 1.3 | 1.4 | -1.0 |
Time >=10cm from walls, locomotor time 2 | 1.5 | 1.6 | 2.3 | -1.2 | -1.4 | 1.3 | -0.8 | -1.4 | -1.4 | -1.5 | 1.3 | -1.4 | 1.3 | -1.2 | -1.5 | 1.2 | -1.3 | -1.3 | 1.5 | -1.2 | -1.3 | -1.3 | 1.2 | -1.0 | -1.3 | -1.1 | -1.3 | 1.2 | -1.3 | -1.3 | -0.7 | 0.9 | -1.3 | -1.2 | -1.3 | 1.4 | 1.3 | -1.3 |
Mean num. licks in bursts | 1.4 | 1.7 | 2.4 | -1.4 | -1.5 | 1.3 | -0.3 | -1.5 | -1.4 | -1.4 | 1.3 | -1.4 | 1.3 | -1.3 | -1.4 | 1.4 | -1.3 | -1.3 | 1.4 | -1.3 | -1.3 | -1.3 | 1.3 | -1.1 | -1.4 | -1.2 | -1.3 | 1.3 | -1.3 | -1.4 | -0.4 | 0.8 | -1.4 | -1.5 | -1.3 | 1.4 | 1.4 | -1.3 |
Indifference point function ln k | 1.4 | 2.0 | 3.5 | -1.6 | -1.2 | 1.5 | -0.0 | -1.4 | -1.6 | -1.9 | 1.5 | -1.4 | 1.3 | -1.3 | -1.8 | 1.6 | -1.3 | -1.2 | 1.6 | -1.3 | -1.5 | -1.3 | 1.3 | -0.8 | -1.6 | -1.1 | -1.5 | 1.3 | -1.6 | -1.6 | 0.0 | 0.5 | -1.6 | -1.5 | -1.6 | 1.6 | 1.4 | -1.6 |
Indifference point function log k | 1.4 | 2.0 | 3.5 | -1.6 | -1.2 | 1.5 | -0.0 | -1.4 | -1.6 | -1.9 | 1.5 | -1.4 | 1.3 | -1.3 | -1.8 | 1.6 | -1.3 | -1.2 | 1.6 | -1.3 | -1.5 | -1.3 | 1.3 | -0.8 | -1.6 | -1.1 | -1.5 | 1.3 | -1.6 | -1.6 | 0.0 | 0.5 | -1.6 | -1.5 | -1.6 | 1.6 | 1.4 | -1.6 |
Condit. Reinf. active-inactive response ratio | 1.4 | 1.5 | 2.1 | 1.3 | 1.4 | -1.1 | 0.9 | 1.3 | 1.4 | 1.4 | -1.2 | 1.3 | -1.3 | 1.3 | 1.4 | -1.3 | 1.3 | 1.2 | -1.3 | 1.2 | 1.2 | 1.2 | -1.2 | 1.1 | 1.3 | 1.2 | 1.4 | -1.3 | 1.1 | 1.3 | 0.9 | -1.0 | 1.3 | 1.4 | 1.1 | -1.3 | -1.2 | 1.1 |
Locomotion velocity, hab. session 1 | 1.4 | 2.0 | 2.7 | -1.3 | -1.6 | 1.5 | -0.9 | -1.7 | -1.4 | -1.4 | 1.4 | -1.5 | 1.4 | -1.4 | -1.5 | 1.4 | -1.4 | -1.5 | 1.4 | -1.4 | -1.5 | -1.5 | 1.4 | -1.2 | -1.3 | -1.3 | -1.3 | 1.3 | -1.5 | -1.3 | -0.9 | 1.2 | -1.4 | -1.5 | -1.5 | 1.4 | 1.5 | -1.4 |
Total heroin consumption | 1.4 | 1.7 | 4.0 | -1.4 | -0.7 | 1.3 | -2.0 | -1.0 | -1.2 | -1.1 | 1.3 | -1.1 | 1.3 | -1.4 | -1.0 | 1.1 | -1.3 | -1.2 | 1.3 | -1.3 | -1.4 | -1.0 | 1.3 | -1.5 | -1.3 | -1.4 | -1.4 | 1.4 | -1.3 | -1.3 | -1.8 | 1.6 | -1.2 | -1.2 | -1.3 | 1.2 | 1.1 | -1.3 |
Seeking ratio, punishment vs. effort | 1.4 | 1.7 | 2.8 | -1.4 | -0.8 | 1.3 | -1.3 | -1.1 | -1.4 | -1.5 | 1.2 | -1.1 | 1.3 | -1.3 | -1.4 | 1.4 | -1.3 | -1.1 | 1.6 | -1.3 | -1.2 | -1.7 | 1.3 | -1.0 | -1.3 | -1.2 | -1.3 | 1.3 | -1.2 | -1.3 | -0.8 | 1.0 | -1.6 | -1.2 | -1.2 | 1.4 | 1.7 | -1.2 |
Na content in liver | 1.4 | 1.5 | 2.8 | -1.4 | -1.1 | 1.2 | -0.3 | -1.1 | -1.4 | -1.5 | 1.2 | -1.2 | 1.3 | -1.3 | -1.3 | 1.3 | -1.3 | -1.0 | 1.3 | -1.2 | -1.1 | -1.0 | 1.2 | -1.1 | -1.4 | -1.2 | -1.7 | 1.3 | -1.1 | -1.4 | -0.2 | 0.7 | -1.3 | -1.4 | -1.1 | 1.4 | 1.3 | -1.1 |
Saline control response | 1.3 | 1.7 | 2.4 | -1.5 | -1.1 | 1.1 | -1.5 | -1.0 | -1.4 | -1.4 | 1.2 | -1.2 | 1.4 | -1.4 | -1.5 | 1.4 | -1.4 | -0.8 | 1.4 | -1.3 | -1.0 | -1.6 | 1.3 | -1.3 | -1.5 | -1.3 | -1.5 | 1.4 | -0.9 | -1.5 | -1.1 | 1.2 | -1.5 | -1.3 | -0.9 | 1.4 | 1.5 | -1.0 |
Short access day 10 total locomotion | 1.3 | 1.4 | 2.1 | -1.2 | -1.3 | 1.1 | -1.3 | -1.2 | -1.2 | -1.2 | 1.2 | -1.2 | 1.2 | -1.2 | -1.3 | 1.2 | -1.2 | -1.0 | 1.2 | -1.2 | -1.2 | -0.9 | 1.2 | -1.2 | -1.2 | -1.2 | -1.2 | 1.2 | -1.2 | -1.2 | -1.4 | 1.3 | -1.2 | -1.3 | -1.2 | 1.2 | 1.0 | -1.2 |
Liver weight, left | 1.2 | 1.9 | 3.9 | 1.4 | 1.3 | -1.2 | 2.0 | 1.3 | 1.3 | 1.1 | -1.3 | 1.2 | -1.4 | 1.4 | 1.2 | -1.3 | 1.4 | 1.2 | -1.1 | 1.4 | 1.2 | 1.3 | -1.3 | 1.6 | 1.4 | 1.5 | 1.3 | -1.4 | 1.2 | 1.4 | 1.9 | -1.7 | 1.2 | 1.4 | 1.2 | -1.3 | -1.3 | 1.2 |
Number of licking bursts | 1.2 | 1.4 | 1.9 | 1.2 | 1.2 | -1.2 | 0.4 | 1.3 | 1.3 | 1.4 | -1.2 | 1.3 | -1.2 | 1.2 | 1.3 | -1.3 | 1.2 | 1.3 | -1.3 | 1.2 | 1.2 | 1.3 | -1.2 | 0.9 | 1.2 | 1.1 | 1.2 | -1.2 | 1.2 | 1.2 | 0.3 | -0.7 | 1.3 | 1.2 | 1.2 | -1.3 | -1.3 | 1.2 |
Delay discounting total patch changes 24 sec | 1.2 | 1.5 | 2.0 | 1.2 | 1.2 | -1.4 | 0.9 | 1.3 | 1.2 | 1.2 | -1.3 | 1.3 | -1.2 | 1.2 | 1.3 | -1.3 | 1.2 | 1.4 | -1.3 | 1.3 | 1.4 | 1.2 | -1.3 | 1.2 | 1.2 | 1.2 | 1.2 | -1.2 | 1.3 | 1.3 | 0.7 | -1.0 | 1.3 | 1.2 | 1.3 | -1.2 | -1.4 | 1.3 |
Condit. Reinf. lever presses | 1.2 | 1.7 | 3.7 | -1.1 | -1.7 | 1.2 | -1.4 | -1.6 | -1.2 | -1.0 | 1.2 | -1.4 | 1.2 | -1.3 | -1.3 | 1.1 | -1.3 | -1.3 | 1.2 | -1.3 | -1.2 | -0.8 | 1.3 | -1.4 | -1.1 | -1.3 | -1.1 | 1.3 | -1.2 | -1.1 | -1.9 | 1.6 | -1.1 | -1.5 | -1.2 | 1.1 | 0.8 | -1.2 |
Delay discounting total patch changes 12 sec | 1.1 | 1.5 | 2.2 | 1.1 | 1.3 | -1.2 | 1.0 | 1.4 | 1.2 | 1.2 | -1.2 | 1.3 | -1.2 | 1.2 | 1.3 | -1.4 | 1.2 | 1.5 | -1.3 | 1.3 | 1.4 | 1.1 | -1.4 | 1.1 | 1.1 | 1.2 | 1.0 | -1.2 | 1.3 | 1.2 | 0.9 | -1.2 | 1.4 | 1.2 | 1.3 | -1.2 | -1.2 | 1.3 |
Light reinforcement 2 | 1.1 | 1.4 | 2.5 | -1.3 | -1.4 | 1.0 | -1.2 | -1.3 | -1.1 | -0.9 | 1.1 | -1.1 | 1.3 | -1.3 | -0.9 | 1.0 | -1.3 | -1.1 | 1.0 | -1.3 | -1.0 | -0.9 | 1.2 | -1.6 | -1.3 | -1.4 | -1.3 | 1.3 | -1.0 | -1.2 | -1.4 | 1.4 | -0.9 | -1.4 | -1.0 | 1.1 | 1.0 | -1.0 |
Intermittent access total locomotion | 1.1 | 1.2 | 2.3 | -1.0 | -0.9 | 1.2 | -1.5 | -0.8 | -1.0 | -1.0 | 1.2 | -1.1 | 1.0 | -1.0 | -1.0 | 1.1 | -1.0 | -0.8 | 1.1 | -1.1 | -1.2 | -1.3 | 1.1 | -1.0 | -1.0 | -1.0 | -1.0 | 1.0 | -1.3 | -1.0 | -1.1 | 1.0 | -1.1 | -0.9 | -1.3 | 1.0 | 1.5 | -1.2 |
Incentive Sensitization - Responses | 1.1 | 1.1 | 2.1 | -1.4 | -0.2 | 1.1 | -0.1 | -0.7 | -1.3 | -1.5 | 1.1 | -0.8 | 1.1 | -1.1 | -1.2 | 1.1 | -1.0 | -0.8 | 1.0 | -0.8 | -1.1 | -1.0 | 0.7 | -0.8 | -1.4 | -0.8 | -1.5 | 1.0 | -1.0 | -1.4 | 0.4 | 0.1 | -1.0 | -1.0 | -1.0 | 1.3 | 1.3 | -1.0 |
Total locomotion distance, NPP test | 1.1 | 1.6 | 3.1 | -1.2 | -1.2 | 1.0 | -1.8 | -1.2 | -1.2 | -1.0 | 1.1 | -1.1 | 1.3 | -1.3 | -1.1 | 1.3 | -1.3 | -1.0 | 1.3 | -1.3 | -1.0 | -1.2 | 1.3 | -1.5 | -1.2 | -1.4 | -1.3 | 1.3 | -1.0 | -1.2 | -1.7 | 1.7 | -1.3 | -1.3 | -1.0 | 1.2 | 1.1 | -1.0 |
Time to tail flick, test, before self-admin | 1.1 | 1.1 | 1.7 | -1.0 | -0.9 | 1.2 | -0.9 | -1.1 | -1.0 | -1.0 | 1.2 | -1.1 | 1.0 | -1.0 | -1.0 | 0.9 | -1.0 | -1.3 | 0.8 | -1.0 | -1.2 | -0.7 | 0.9 | -1.1 | -1.1 | -1.0 | -1.1 | 1.0 | -1.3 | -1.1 | -0.8 | 0.9 | -0.8 | -1.1 | -1.3 | 1.0 | 0.7 | -1.3 |
Run reversals in cocaine runway, males | 1.1 | 1.1 | 1.6 | -1.0 | -1.2 | 1.1 | -0.7 | -1.1 | -1.1 | -1.2 | 1.1 | -1.1 | 1.0 | -1.0 | -1.2 | 1.2 | -1.0 | -1.0 | 1.1 | -1.0 | -1.1 | -1.3 | 1.1 | -0.7 | -1.0 | -0.9 | -1.0 | 1.0 | -1.1 | -1.0 | -0.6 | 0.7 | -1.1 | -1.1 | -1.1 | 1.1 | 1.3 | -1.1 |
Se content in liver | 1.1 | 1.3 | 2.7 | 1.0 | 1.7 | -1.4 | 0.2 | 1.7 | 1.1 | 1.2 | -1.3 | 1.4 | -1.0 | 1.0 | 1.3 | -1.1 | 1.0 | 1.5 | -1.1 | 1.1 | 1.3 | 1.1 | -1.2 | 0.8 | 1.0 | 0.9 | 0.9 | -1.0 | 1.3 | 1.0 | 0.5 | -0.7 | 1.1 | 1.3 | 1.3 | -1.1 | -1.1 | 1.3 |
Tibialis anterior weight | 1.0 | 3.4 | 12.7 | -1.6 | -1.8 | 1.2 | -3.6 | -1.7 | -1.5 | -1.0 | 1.4 | -1.6 | 1.8 | -1.9 | -1.2 | 1.6 | -1.8 | -1.4 | 1.7 | -2.0 | -1.1 | -2.0 | 1.9 | -2.4 | -1.6 | -2.1 | -1.5 | 1.9 | -1.2 | -1.6 | -3.4 | 2.9 | -1.6 | -1.8 | -1.2 | 1.5 | 1.7 | -1.2 |
Tibia length | 1.0 | 2.7 | 6.9 | 1.3 | 2.0 | -1.6 | 2.2 | 2.0 | 1.2 | 0.9 | -1.6 | 1.7 | -1.5 | 1.6 | 1.2 | -1.4 | 1.6 | 1.9 | -1.4 | 1.7 | 1.7 | 1.1 | -1.7 | 2.0 | 1.3 | 1.8 | 1.6 | -1.6 | 1.8 | 1.3 | 2.6 | -2.3 | 1.3 | 1.8 | 1.8 | -1.3 | -1.1 | 1.7 |
Std. dev. time between licks in bursts | 1.0 | 1.2 | 1.7 | 0.9 | 1.2 | -1.2 | 0.9 | 1.1 | 1.1 | 1.1 | -1.1 | 1.2 | -1.1 | 1.1 | 1.2 | -1.1 | 1.1 | 0.9 | -1.1 | 1.1 | 1.2 | 1.3 | -1.1 | 0.9 | 0.9 | 1.0 | 0.9 | -1.0 | 1.2 | 0.9 | 0.8 | -0.9 | 1.1 | 1.1 | 1.2 | -1.1 | -1.3 | 1.2 |
Delay discounting total patch changes 18 sec | 1.0 | 1.3 | 2.0 | 1.1 | 1.1 | -1.2 | 0.3 | 1.3 | 1.2 | 1.4 | -1.2 | 1.2 | -1.0 | 1.0 | 1.4 | -1.3 | 1.1 | 1.4 | -1.3 | 1.1 | 1.2 | 1.0 | -1.2 | 0.7 | 1.1 | 0.9 | 1.0 | -1.0 | 1.2 | 1.2 | 0.3 | -0.6 | 1.3 | 1.2 | 1.2 | -1.2 | -1.2 | 1.2 |
Condit. Reinf. active responses | 1.0 | 1.4 | 5.4 | -0.9 | -1.5 | 0.8 | -1.8 | -1.5 | -0.9 | -0.5 | 1.0 | -1.2 | 1.2 | -1.2 | -0.7 | 0.9 | -1.2 | -1.2 | 1.0 | -1.3 | -0.9 | -0.7 | 1.3 | -1.7 | -0.9 | -1.4 | -0.9 | 1.2 | -0.9 | -0.9 | -2.3 | 2.0 | -1.0 | -1.4 | -0.9 | 0.9 | 0.7 | -0.9 |
Novelty place preference | 1.0 | 1.0 | 2.6 | 0.9 | 0.7 | -1.1 | 1.6 | 0.7 | 0.8 | 0.7 | -1.0 | 1.0 | -1.0 | 1.0 | 0.7 | -1.0 | 1.0 | 0.9 | -0.9 | 1.0 | 1.0 | 1.2 | -1.0 | 1.1 | 0.9 | 1.1 | 0.8 | -1.0 | 1.1 | 0.9 | 1.2 | -1.1 | 0.9 | 0.7 | 1.1 | -0.9 | -1.1 | 1.1 |
Bone: trabecular spacing | 1.0 | 1.4 | 3.4 | 1.0 | 1.2 | -1.2 | 1.8 | 1.2 | 0.9 | 0.7 | -1.1 | 1.2 | -1.1 | 1.1 | 0.7 | -1.0 | 1.1 | 1.1 | -0.9 | 1.2 | 1.2 | 1.2 | -1.2 | 1.5 | 1.0 | 1.3 | 1.0 | -1.2 | 1.2 | 1.0 | 1.7 | -1.6 | 0.9 | 1.1 | 1.2 | -0.9 | -1.1 | 1.1 |
Delay discounting water rate 18 sec | 0.9 | 1.2 | 2.9 | -1.3 | -0.8 | 1.1 | -0.0 | -1.0 | -1.4 | -1.7 | 1.1 | -1.0 | 1.0 | -1.0 | -1.6 | 1.2 | -1.0 | -0.7 | 1.1 | -0.8 | -1.2 | -1.3 | 0.8 | -0.3 | -1.3 | -0.7 | -1.1 | 0.9 | -1.1 | -1.2 | 0.2 | 0.1 | -1.2 | -1.1 | -1.1 | 1.3 | 1.3 | -1.2 |
Condit. Reinf. lever reinforcers received | 0.9 | 1.3 | 5.3 | -0.8 | -1.5 | 0.7 | -1.8 | -1.5 | -0.8 | -0.4 | 0.9 | -1.1 | 1.1 | -1.1 | -0.7 | 0.8 | -1.1 | -1.1 | 0.9 | -1.2 | -0.8 | -0.6 | 1.2 | -1.6 | -0.8 | -1.4 | -0.9 | 1.1 | -0.8 | -0.8 | -2.3 | 2.0 | -0.9 | -1.3 | -0.8 | 0.8 | 0.7 | -0.8 |
Pavlov. Cond. lever latency | 0.9 | 1.3 | 2.4 | 0.9 | 1.5 | -1.2 | 1.0 | 1.5 | 1.0 | 0.9 | -1.2 | 1.3 | -1.1 | 1.1 | 1.1 | -1.0 | 1.1 | 1.3 | -1.0 | 1.2 | 1.2 | 0.8 | -1.2 | 1.2 | 0.9 | 1.2 | 1.0 | -1.1 | 1.2 | 0.9 | 1.3 | -1.3 | 1.0 | 1.3 | 1.2 | -1.0 | -0.7 | 1.2 |
Intermittent access intake escalation | 0.9 | 0.9 | 1.7 | -1.0 | -0.6 | 1.1 | -0.7 | -0.8 | -1.1 | -1.2 | 1.0 | -0.9 | 0.9 | -0.9 | -1.2 | 1.1 | -0.9 | -0.7 | 1.0 | -0.9 | -1.3 | -0.9 | 0.9 | -0.6 | -1.0 | -0.8 | -1.0 | 0.9 | -1.0 | -1.0 | -0.5 | 0.6 | -1.0 | -0.9 | -1.0 | 1.1 | 1.3 | -1.1 |
Locomotion distance, session 7 | 0.9 | 1.1 | 2.0 | 1.1 | 1.2 | -1.1 | -0.1 | 1.2 | 1.2 | 1.4 | -1.1 | 1.2 | -1.0 | 1.0 | 1.3 | -1.1 | 1.0 | 1.4 | -1.1 | 0.9 | 1.0 | 1.1 | -1.0 | 0.6 | 1.1 | 0.8 | 1.0 | -1.0 | 1.1 | 1.1 | -0.1 | -0.3 | 1.1 | 1.0 | 1.1 | -1.2 | -1.1 | 1.1 |
Degree of sensitization distance | 0.9 | 0.9 | 1.2 | 0.9 | 1.1 | -0.7 | 1.1 | 1.0 | 0.9 | 0.9 | -0.8 | 1.0 | -1.0 | 1.0 | 0.9 | -1.0 | 1.0 | 0.9 | -1.0 | 1.0 | 0.8 | 1.1 | -1.0 | 1.0 | 0.9 | 1.0 | 0.9 | -1.0 | 0.7 | 0.9 | 1.0 | -1.0 | 1.0 | 1.0 | 0.7 | -0.9 | -1.0 | 0.8 |
Time in familiar zone, hab. session 1 | 0.9 | 0.9 | 1.9 | 0.8 | 1.4 | -0.9 | 0.8 | 1.3 | 0.9 | 0.8 | -0.9 | 1.0 | -0.9 | 0.9 | 0.9 | -0.8 | 0.9 | 1.1 | -0.8 | 0.9 | 0.9 | 0.7 | -1.0 | 0.9 | 0.8 | 0.9 | 0.8 | -0.9 | 0.9 | 0.8 | 1.1 | -1.0 | 0.8 | 1.1 | 0.9 | -0.9 | -0.8 | 0.9 |
Time in novel zone, NPP test | 0.9 | 1.0 | 2.8 | 0.8 | 0.7 | -1.1 | 1.7 | 0.7 | 0.8 | 0.7 | -1.0 | 1.0 | -0.9 | 1.0 | 0.7 | -0.9 | 0.9 | 0.9 | -0.9 | 1.0 | 1.0 | 1.1 | -1.0 | 1.1 | 0.8 | 1.1 | 0.8 | -1.0 | 1.1 | 0.8 | 1.3 | -1.2 | 0.9 | 0.7 | 1.1 | -0.8 | -1.0 | 1.1 |
Pavlov. Cond. response bias | 0.9 | 1.1 | 1.6 | -1.0 | -0.8 | 1.0 | -1.2 | -0.9 | -1.0 | -0.9 | 1.0 | -0.9 | 1.1 | -1.1 | -0.9 | 1.1 | -1.1 | -0.7 | 1.1 | -1.1 | -0.9 | -0.9 | 1.0 | -1.1 | -1.0 | -1.1 | -1.1 | 1.1 | -1.0 | -1.0 | -1.2 | 1.3 | -1.1 | -1.1 | -1.0 | 1.0 | 0.9 | -1.0 |
Breakpoint value in progressive ratio session | 0.9 | 1.0 | 1.8 | -1.1 | -0.5 | 1.0 | -1.4 | -0.7 | -1.0 | -0.8 | 1.0 | -0.9 | 1.1 | -1.1 | -0.7 | 0.9 | -1.1 | -1.0 | 1.1 | -1.1 | -1.0 | -0.9 | 1.0 | -1.3 | -1.1 | -1.1 | -1.1 | 1.1 | -1.0 | -1.1 | -1.0 | 1.1 | -1.0 | -0.9 | -1.0 | 1.0 | 1.0 | -1.0 |
Delay discounting water rate 0 sec | 0.8 | 1.2 | 2.3 | -1.4 | -1.1 | 0.8 | -0.3 | -1.1 | -1.4 | -1.5 | 1.0 | -1.0 | 1.2 | -1.2 | -1.5 | 1.3 | -1.2 | -1.0 | 1.1 | -1.0 | -0.9 | -1.3 | 1.0 | -0.8 | -1.3 | -1.0 | -1.4 | 1.2 | -0.8 | -1.3 | -0.2 | 0.5 | -1.2 | -1.3 | -0.8 | 1.4 | 1.3 | -0.8 |
Locomotion velocity, session 1 | 0.8 | 0.9 | 1.5 | 0.9 | 1.2 | -1.0 | 0.6 | 1.2 | 1.0 | 1.0 | -1.0 | 1.1 | -0.9 | 0.9 | 1.1 | -0.8 | 0.9 | 1.0 | -0.8 | 0.8 | 1.2 | 1.0 | -0.9 | 0.7 | 0.9 | 0.8 | 0.9 | -0.8 | 1.1 | 0.9 | 0.6 | -0.6 | 0.8 | 1.1 | 1.1 | -0.9 | -1.1 | 1.0 |
Condit. Reinf. inactive responses | 0.8 | 1.0 | 1.4 | -1.1 | -1.1 | 0.8 | -0.6 | -1.0 | -1.1 | -1.0 | 1.0 | -1.0 | 1.1 | -1.1 | -1.0 | 1.2 | -1.1 | -0.8 | 1.1 | -1.1 | -0.9 | -0.9 | 1.1 | -1.1 | -1.1 | -1.1 | -1.0 | 1.1 | -0.8 | -1.1 | -0.6 | 0.9 | -1.1 | -1.1 | -0.8 | 1.1 | 0.9 | -0.9 |
Time to tail flick, test, after self-admin | 0.8 | 0.8 | 1.5 | -1.0 | -0.8 | 0.9 | 0.1 | -0.9 | -1.1 | -1.2 | 1.0 | -0.8 | 0.9 | -0.8 | -1.2 | 1.0 | -0.8 | -0.8 | 0.8 | -0.7 | -0.8 | -0.9 | 0.7 | -0.5 | -1.1 | -0.6 | -1.1 | 0.8 | -0.9 | -1.1 | 0.2 | 0.1 | -0.8 | -1.0 | -0.9 | 1.0 | 0.9 | -0.9 |
Indifference point 0 sec | 0.7 | 1.1 | 2.4 | 0.8 | 1.0 | -1.3 | 1.0 | 1.2 | 1.0 | 1.0 | -1.1 | 1.2 | -0.9 | 0.9 | 1.1 | -1.1 | 1.0 | 1.6 | -1.0 | 1.0 | 1.2 | 1.1 | -1.1 | 0.8 | 0.8 | 0.9 | 0.8 | -0.9 | 1.3 | 0.8 | 0.8 | -0.9 | 1.1 | 1.0 | 1.3 | -1.0 | -1.1 | 1.2 |
Delay discounting total patch changes 0 sec | 0.7 | 1.1 | 2.5 | 0.7 | 1.2 | -1.3 | 0.8 | 1.3 | 0.9 | 1.0 | -1.1 | 1.3 | -0.9 | 0.9 | 1.1 | -1.1 | 0.9 | 1.6 | -1.0 | 1.1 | 1.3 | 1.0 | -1.2 | 0.8 | 0.7 | 0.9 | 0.8 | -0.9 | 1.3 | 0.8 | 0.7 | -0.8 | 1.1 | 1.0 | 1.3 | -1.0 | -1.0 | 1.3 |
Locomotor activity | 0.7 | 1.1 | 2.2 | 0.9 | 1.5 | -1.1 | 1.1 | 1.4 | 1.0 | 0.9 | -1.0 | 1.3 | -0.9 | 0.9 | 1.2 | -0.9 | 1.0 | 1.4 | -0.9 | 1.0 | 1.0 | 1.1 | -1.0 | 0.9 | 1.0 | 1.0 | 0.8 | -0.9 | 1.0 | 1.0 | 1.1 | -1.0 | 0.8 | 1.3 | 1.0 | -0.9 | -1.0 | 1.0 |
Cocaine response after cond. not corrected | 0.7 | 0.8 | 1.2 | -0.9 | -1.0 | 0.9 | -0.6 | -1.0 | -0.9 | -0.8 | 0.9 | -1.0 | 0.9 | -0.9 | -0.8 | 1.0 | -0.9 | -1.1 | 0.9 | -1.0 | -0.9 | -0.9 | 1.0 | -1.0 | -0.9 | -1.0 | -0.9 | 0.9 | -0.9 | -0.9 | -0.5 | 0.8 | -0.9 | -0.9 | -0.9 | 0.9 | 0.9 | -0.9 |
Condit. Reinf. active-inactive response ratio | 0.7 | 0.7 | 1.1 | -0.8 | -1.0 | 0.7 | -0.7 | -1.0 | -0.8 | -0.7 | 0.8 | -0.9 | 0.9 | -0.9 | -0.8 | 0.9 | -0.9 | -1.1 | 0.9 | -0.9 | -0.7 | -0.6 | 0.9 | -1.0 | -0.8 | -0.9 | -0.8 | 0.9 | -0.7 | -0.8 | -0.8 | 0.9 | -0.8 | -0.9 | -0.7 | 0.8 | 0.7 | -0.7 |
Intermittent access day 15 total locomotion | 0.7 | 0.8 | 2.5 | -0.6 | -0.8 | 1.0 | -1.6 | -0.7 | -0.7 | -0.6 | 1.0 | -0.9 | 0.7 | -0.8 | -0.7 | 0.7 | -0.8 | -0.7 | 0.8 | -0.9 | -0.9 | -1.0 | 0.9 | -0.8 | -0.6 | -0.8 | -0.6 | 0.8 | -1.1 | -0.6 | -1.3 | 1.1 | -0.8 | -0.7 | -1.1 | 0.7 | 1.2 | -1.0 |
Intermittent access standard deviation | 0.7 | 0.8 | 1.7 | -0.8 | -0.6 | 0.8 | -1.3 | -0.5 | -0.9 | -0.9 | 0.8 | -0.8 | 0.9 | -0.9 | -0.9 | 0.8 | -0.9 | -0.2 | 1.0 | -0.9 | -0.9 | -1.3 | 0.9 | -0.8 | -0.8 | -0.8 | -0.8 | 0.9 | -0.7 | -0.8 | -1.0 | 0.9 | -1.0 | -0.8 | -0.7 | 0.9 | 1.2 | -0.8 |
Incentive Sensitization - Breakpoint | 0.7 | 0.7 | 1.5 | -1.2 | -0.0 | 0.9 | 0.2 | -0.5 | -1.0 | -1.2 | 0.9 | -0.6 | 0.8 | -0.8 | -1.0 | 0.9 | -0.8 | -0.5 | 0.7 | -0.5 | -0.9 | -0.8 | 0.5 | -0.5 | -1.2 | -0.6 | -1.2 | 0.8 | -0.7 | -1.2 | 0.6 | -0.1 | -0.7 | -0.8 | -0.7 | 1.0 | 1.0 | -0.8 |
Total locomotion distance, hab. session 1 | 0.7 | 0.9 | 1.4 | -1.0 | -1.1 | 1.0 | -0.4 | -1.2 | -1.0 | -1.1 | 1.0 | -1.1 | 0.9 | -0.9 | -1.2 | 1.1 | -0.9 | -1.0 | 1.0 | -0.9 | -1.0 | -1.2 | 1.0 | -0.7 | -1.0 | -0.8 | -0.9 | 0.9 | -1.0 | -1.0 | -0.4 | 0.6 | -1.0 | -1.1 | -1.0 | 1.0 | 1.1 | -0.9 |
Total zone transitions, NPP test | 0.7 | 1.0 | 2.9 | -1.0 | -0.7 | 0.6 | -1.7 | -0.7 | -1.0 | -0.9 | 0.8 | -0.8 | 1.1 | -1.1 | -0.9 | 1.2 | -1.1 | -0.7 | 1.1 | -1.1 | -0.7 | -1.0 | 1.0 | -1.1 | -1.0 | -1.1 | -1.0 | 1.1 | -0.6 | -1.0 | -1.5 | 1.4 | -1.1 | -0.9 | -0.6 | 1.0 | 1.0 | -0.7 |
Time in closed arm after self-admin | 0.7 | 0.7 | 1.5 | 0.9 | 1.2 | -0.6 | 0.6 | 1.0 | 0.9 | 0.8 | -0.8 | 0.9 | -0.9 | 0.9 | 0.9 | -0.9 | 0.9 | 0.9 | -0.8 | 0.9 | 0.8 | 0.9 | -0.9 | 0.9 | 0.9 | 0.9 | 0.9 | -0.9 | 0.7 | 0.8 | 0.8 | -0.8 | 0.8 | 1.0 | 0.7 | -0.9 | -0.7 | 0.7 |
Time to tail flick, vehicle, before self-admin | 0.7 | 0.7 | 1.2 | 0.6 | 1.0 | -0.7 | 1.1 | 0.9 | 0.7 | 0.6 | -0.7 | 0.8 | -0.8 | 0.8 | 0.6 | -0.9 | 0.8 | 0.7 | -1.0 | 1.0 | 0.9 | 1.1 | -1.0 | 0.9 | 0.6 | 0.9 | 0.6 | -0.8 | 0.6 | 0.5 | 0.9 | -1.0 | 1.0 | 0.7 | 0.6 | -0.7 | -1.1 | 0.7 |
Times rat made contact with spout | 0.6 | 0.7 | 1.4 | -0.8 | -1.2 | 0.7 | -0.7 | -1.0 | -0.7 | -0.6 | 0.8 | -0.9 | 0.8 | -0.8 | -0.7 | 0.7 | -0.8 | -0.8 | 0.7 | -0.9 | -0.8 | -0.6 | 0.9 | -1.0 | -0.8 | -0.9 | -0.8 | 0.8 | -0.8 | -0.8 | -1.0 | 1.0 | -0.7 | -1.0 | -0.8 | 0.7 | 0.6 | -0.8 |
Stereotopy head waving duration, day 3 | 0.6 | 0.7 | 1.1 | -0.9 | -1.0 | 0.9 | -0.2 | -1.1 | -0.9 | -0.9 | 0.9 | -0.9 | 0.9 | -0.9 | -0.9 | 0.8 | -0.9 | -1.0 | 0.8 | -0.8 | -0.9 | -0.6 | 0.8 | -0.8 | -0.9 | -0.8 | -0.9 | 0.9 | -0.9 | -0.9 | -0.5 | 0.6 | -0.8 | -1.0 | -0.9 | 0.9 | 0.6 | -0.9 |
Novel to familiar place preference ratio | 0.6 | 0.6 | 2.2 | 0.7 | 0.5 | -0.9 | 1.5 | 0.5 | 0.6 | 0.5 | -0.8 | 0.8 | -0.8 | 0.8 | 0.5 | -0.8 | 0.8 | 0.7 | -0.7 | 0.8 | 0.8 | 1.0 | -0.8 | 0.9 | 0.7 | 0.9 | 0.6 | -0.8 | 0.9 | 0.7 | 1.0 | -1.0 | 0.7 | 0.5 | 0.9 | -0.7 | -0.9 | 0.9 |
Bone surface | 0.6 | 1.0 | 3.4 | -1.0 | -0.7 | 0.8 | -1.8 | -0.8 | -0.9 | -0.6 | 0.9 | -0.9 | 1.0 | -1.0 | -0.7 | 0.9 | -1.0 | -0.8 | 0.9 | -1.0 | -0.9 | -1.0 | 1.0 | -1.3 | -1.0 | -1.2 | -1.0 | 1.1 | -0.8 | -1.0 | -1.6 | 1.4 | -0.9 | -0.9 | -0.8 | 0.9 | 1.0 | -0.8 |
Bone: elastic work | 0.6 | 0.7 | 1.3 | -0.8 | -1.0 | 0.8 | -1.0 | -1.0 | -0.7 | -0.6 | 0.8 | -1.0 | 0.8 | -0.8 | -0.6 | 0.6 | -0.8 | -1.1 | 0.7 | -0.9 | -0.8 | -1.0 | 0.9 | -1.0 | -0.8 | -0.9 | -0.6 | 0.8 | -0.8 | -0.8 | -0.9 | 0.9 | -0.7 | -0.7 | -0.8 | 0.7 | 1.1 | -0.9 |
Bone: minimum diameter | 0.6 | 1.1 | 2.2 | 0.8 | 1.5 | -1.4 | 0.2 | 1.4 | 1.0 | 1.0 | -1.2 | 1.3 | -0.9 | 0.9 | 1.1 | -1.0 | 0.9 | 1.5 | -1.0 | 1.0 | 1.4 | 0.4 | -1.1 | 0.8 | 0.8 | 0.9 | 0.9 | -0.9 | 1.4 | 0.8 | 0.5 | -0.7 | 1.0 | 1.2 | 1.4 | -1.0 | -0.6 | 1.4 |
Bouts of movement, locomotor time 2 | 0.6 | 0.6 | 1.1 | 0.6 | 0.5 | -1.0 | 0.6 | 0.6 | 0.7 | 0.8 | -0.8 | 0.8 | -0.8 | 0.8 | 0.6 | -0.8 | 0.8 | 0.8 | -0.8 | 0.8 | 0.8 | 1.0 | -0.8 | 0.8 | 0.8 | 0.8 | 0.8 | -0.8 | 0.8 | 0.8 | 0.2 | -0.5 | 0.9 | 0.5 | 0.8 | -0.8 | -1.0 | 0.8 |
Total resting periods, locomotor time 2 | 0.6 | 0.7 | 1.2 | 0.7 | 0.3 | -1.0 | 0.4 | 0.6 | 0.8 | 1.0 | -0.9 | 0.8 | -0.8 | 0.8 | 0.8 | -0.8 | 0.8 | 0.9 | -0.9 | 0.8 | 0.9 | 1.1 | -0.8 | 0.7 | 0.9 | 0.7 | 0.9 | -0.8 | 0.9 | 0.9 | -0.1 | -0.4 | 1.0 | 0.5 | 0.9 | -0.9 | -1.1 | 0.9 |
Latency to leave start box in cocaine runway | 0.6 | 0.7 | 1.6 | -0.7 | -1.3 | 1.0 | -0.4 | -1.2 | -0.7 | -0.7 | 0.9 | -1.0 | 0.7 | -0.7 | -0.8 | 0.6 | -0.7 | -1.2 | 0.7 | -0.8 | -1.0 | -0.8 | 0.9 | -0.7 | -0.6 | -0.8 | -0.6 | 0.7 | -1.0 | -0.6 | -0.5 | 0.7 | -0.7 | -0.8 | -1.0 | 0.7 | 0.8 | -1.0 |
Light reinforcement 1 | 0.5 | 0.9 | 3.2 | -1.1 | -0.9 | 0.4 | -1.4 | -0.9 | -0.8 | -0.4 | 0.7 | -0.6 | 1.1 | -1.1 | -0.4 | 0.8 | -1.1 | -0.3 | 0.8 | -1.1 | -0.5 | -0.5 | 1.0 | -1.7 | -1.1 | -1.3 | -1.0 | 1.2 | -0.4 | -1.1 | -1.8 | 1.7 | -0.7 | -1.1 | -0.4 | 0.8 | 0.6 | -0.5 |
Pavlov. Cond. response bias | 0.5 | 0.7 | 1.8 | -0.5 | -1.2 | 0.9 | -0.9 | -1.2 | -0.6 | -0.5 | 0.8 | -1.0 | 0.8 | -0.8 | -0.7 | 0.7 | -0.8 | -1.0 | 0.7 | -0.9 | -0.9 | -0.4 | 0.9 | -0.9 | -0.5 | -0.9 | -0.7 | 0.8 | -0.9 | -0.5 | -1.3 | 1.1 | -0.7 | -0.9 | -0.9 | 0.6 | 0.4 | -0.9 |
Stereotopy head waving duration, day 7 | 0.5 | 0.6 | 1.4 | -0.7 | -1.2 | 0.7 | -0.3 | -1.1 | -0.7 | -0.7 | 0.8 | -0.9 | 0.7 | -0.7 | -0.8 | 0.7 | -0.8 | -1.0 | 0.7 | -0.8 | -0.7 | -0.5 | 0.8 | -0.7 | -0.7 | -0.8 | -0.7 | 0.7 | -0.7 | -0.7 | -0.6 | 0.7 | -0.7 | -1.0 | -0.7 | 0.7 | 0.6 | -0.8 |
Locomotion velocity, session 8 | 0.5 | 0.6 | 0.8 | -0.8 | -0.7 | 0.8 | -0.6 | -0.9 | -0.8 | -0.9 | 0.8 | -0.8 | 0.8 | -0.8 | -0.9 | 0.9 | -0.8 | -0.9 | 0.9 | -0.8 | -0.9 | -0.7 | 0.9 | -0.7 | -0.8 | -0.8 | -0.7 | 0.8 | -0.8 | -0.8 | -0.6 | 0.7 | -0.9 | -0.8 | -0.8 | 0.8 | 0.8 | -0.8 |
Bone: cortical thickness | 0.5 | 0.6 | 1.8 | -0.7 | -0.7 | 0.6 | -1.4 | -0.7 | -0.6 | -0.5 | 0.6 | -0.7 | 0.7 | -0.7 | -0.6 | 0.6 | -0.7 | -0.7 | 0.6 | -0.7 | -0.6 | -0.9 | 0.7 | -0.9 | -0.7 | -0.8 | -0.7 | 0.8 | -0.6 | -0.7 | -1.2 | 1.0 | -0.6 | -0.7 | -0.6 | 0.6 | 0.9 | -0.6 |
Bone: tissue strength | 0.5 | 0.5 | 1.5 | 0.8 | 0.4 | -0.5 | 1.2 | 0.4 | 0.7 | 0.5 | -0.6 | 0.5 | -0.8 | 0.8 | 0.4 | -0.6 | 0.7 | 0.3 | -0.5 | 0.7 | 0.5 | 0.5 | -0.5 | 1.0 | 0.8 | 0.8 | 0.8 | -0.8 | 0.5 | 0.8 | 1.1 | -1.0 | 0.6 | 0.6 | 0.5 | -0.7 | -0.5 | 0.5 |
Delta time in closed arm before/after self-admin | 0.5 | 0.5 | 1.6 | 0.4 | 1.3 | -1.0 | -0.1 | 1.0 | 0.6 | 0.6 | -0.8 | 0.9 | -0.5 | 0.5 | 0.8 | -0.8 | 0.6 | 0.9 | -0.7 | 0.7 | 0.9 | 0.6 | -0.8 | 0.3 | 0.4 | 0.5 | 0.4 | -0.5 | 0.9 | 0.3 | 0.2 | -0.4 | 0.7 | 0.7 | 0.9 | -0.6 | -0.5 | 0.9 |
Delta ambulatory time before/after self-admin | 0.5 | 0.6 | 0.8 | 0.5 | 0.8 | -0.9 | 0.9 | 0.9 | 0.7 | 0.7 | -0.8 | 0.8 | -0.7 | 0.7 | 0.8 | -0.9 | 0.7 | 0.9 | -0.8 | 0.8 | 0.8 | 0.9 | -0.8 | 0.6 | 0.5 | 0.7 | 0.5 | -0.7 | 0.9 | 0.5 | 0.8 | -0.8 | 0.8 | 0.7 | 0.9 | -0.7 | -0.8 | 0.8 |
Rb content in liver | 0.5 | 0.7 | 1.6 | 0.6 | 1.3 | -1.0 | 0.3 | 1.2 | 0.8 | 0.9 | -0.8 | 1.0 | -0.7 | 0.7 | 1.0 | -0.8 | 0.7 | 1.2 | -0.8 | 0.7 | 0.8 | 1.1 | -0.8 | 0.4 | 0.6 | 0.6 | 0.6 | -0.6 | 0.9 | 0.6 | 0.3 | -0.4 | 0.8 | 0.9 | 0.9 | -0.8 | -1.0 | 0.9 |
BMI without tail | 0.4 | 0.8 | 1.4 | 1.0 | 0.8 | -0.7 | 0.6 | 0.7 | 1.1 | 1.1 | -0.8 | 0.7 | -1.0 | 1.0 | 1.1 | -1.1 | 1.0 | 0.7 | -1.1 | 0.9 | 0.7 | 0.9 | -0.9 | 0.8 | 1.1 | 0.9 | 1.1 | -0.9 | 0.7 | 1.0 | 0.3 | -0.6 | 1.0 | 1.1 | 0.7 | -1.0 | -1.2 | 0.8 |
Left kidney weight | 0.4 | 1.2 | 3.1 | -1.2 | -0.7 | 1.0 | -0.9 | -0.8 | -1.3 | -1.5 | 1.0 | -1.0 | 1.1 | -1.0 | -1.5 | 1.2 | -1.0 | -0.8 | 1.3 | -0.9 | -1.0 | -1.7 | 0.9 | -0.5 | -1.2 | -0.8 | -1.2 | 1.0 | -0.9 | -1.1 | -0.3 | 0.4 | -1.2 | -1.1 | -0.9 | 1.3 | 1.6 | -1.0 |
Locomotor testing rearing | 0.4 | 0.6 | 1.8 | -0.7 | -0.5 | 0.6 | -1.3 | -0.4 | -0.7 | -0.5 | 0.6 | -0.5 | 0.9 | -0.9 | -0.4 | 0.7 | -0.9 | -0.2 | 0.9 | -0.9 | -0.7 | -0.5 | 0.8 | -1.2 | -0.7 | -1.0 | -0.8 | 0.9 | -0.5 | -0.7 | -1.3 | 1.3 | -0.8 | -0.6 | -0.5 | 0.7 | 0.5 | -0.6 |
Pavlov. Cond. index score | 0.4 | 0.5 | 1.8 | -0.5 | -1.0 | 0.8 | -1.0 | -1.0 | -0.6 | -0.4 | 0.7 | -0.9 | 0.6 | -0.7 | -0.6 | 0.5 | -0.7 | -0.9 | 0.6 | -0.7 | -0.8 | -0.3 | 0.8 | -0.8 | -0.5 | -0.8 | -0.6 | 0.7 | -0.8 | -0.5 | -1.3 | 1.1 | -0.5 | -0.8 | -0.8 | 0.6 | 0.2 | -0.7 |
Pavlov. Cond. latency score | 0.4 | 0.6 | 1.9 | -0.5 | -1.0 | 0.8 | -1.0 | -1.0 | -0.6 | -0.4 | 0.7 | -0.8 | 0.7 | -0.7 | -0.7 | 0.5 | -0.7 | -0.9 | 0.6 | -0.7 | -0.8 | -0.3 | 0.8 | -0.8 | -0.5 | -0.8 | -0.7 | 0.7 | -0.8 | -0.5 | -1.4 | 1.1 | -0.5 | -0.9 | -0.8 | 0.6 | 0.2 | -0.8 |
Condit. Reinf. lever presses | 0.4 | 0.6 | 0.8 | -0.8 | -0.5 | 0.7 | -0.1 | -0.7 | -0.8 | -0.9 | 0.7 | -0.6 | 0.8 | -0.8 | -0.7 | 0.9 | -0.8 | -0.6 | 0.9 | -0.8 | -0.6 | -0.7 | 0.8 | -0.7 | -0.8 | -0.8 | -0.9 | 0.8 | -0.7 | -0.8 | -0.1 | 0.5 | -0.9 | -0.9 | -0.7 | 0.8 | 0.8 | -0.7 |
Pavlov. Cond. lever latency | 0.4 | 0.6 | 2.0 | 0.7 | 0.4 | -0.6 | 1.4 | 0.5 | 0.6 | 0.5 | -0.6 | 0.5 | -0.8 | 0.8 | 0.5 | -0.8 | 0.8 | 0.4 | -0.8 | 0.8 | 0.5 | 0.7 | -0.8 | 1.0 | 0.7 | 0.9 | 0.8 | -0.8 | 0.6 | 0.7 | 1.2 | -1.2 | 0.8 | 0.7 | 0.6 | -0.6 | -0.6 | 0.6 |
Pavlov. Cond. lever-magazine prob. diff. | 0.4 | 0.5 | 1.5 | -0.6 | -0.3 | 0.5 | -1.2 | -0.5 | -0.6 | -0.4 | 0.6 | -0.4 | 0.7 | -0.7 | -0.5 | 0.7 | -0.7 | -0.3 | 0.7 | -0.7 | -0.4 | -0.5 | 0.7 | -0.9 | -0.6 | -0.8 | -0.8 | 0.7 | -0.5 | -0.6 | -1.2 | 1.1 | -0.7 | -0.7 | -0.5 | 0.6 | 0.5 | -0.6 |
Bone: trabecular thickness | 0.4 | 0.5 | 0.8 | -0.7 | -0.8 | 0.7 | -0.8 | -0.9 | -0.6 | -0.6 | 0.8 | -0.8 | 0.7 | -0.7 | -0.6 | 0.6 | -0.7 | -0.8 | 0.6 | -0.7 | -0.8 | -0.7 | 0.7 | -0.8 | -0.7 | -0.7 | -0.8 | 0.7 | -0.8 | -0.7 | -0.8 | 0.8 | -0.6 | -0.8 | -0.8 | 0.7 | 0.7 | -0.7 |
Distance traveled after self-admin | 0.4 | 0.4 | 2.3 | 0.5 | 0.6 | -0.6 | 1.5 | 0.7 | 0.4 | 0.2 | -0.5 | 0.6 | -0.6 | 0.6 | 0.3 | -0.4 | 0.6 | 0.8 | -0.3 | 0.6 | 0.4 | 0.5 | -0.5 | 0.9 | 0.6 | 0.7 | 0.6 | -0.6 | 0.5 | 0.5 | 1.4 | -1.1 | 0.3 | 0.6 | 0.5 | -0.4 | -0.7 | 0.4 |
Extinction: sum of active levers before priming | 0.4 | 0.4 | 2.1 | -0.9 | 0.1 | 0.4 | -1.5 | 0.0 | -0.7 | -0.7 | 0.5 | -0.3 | 0.7 | -0.7 | -0.5 | 0.6 | -0.7 | -0.2 | 0.8 | -0.6 | -0.4 | -0.8 | 0.5 | -0.7 | -0.8 | -0.7 | -0.8 | 0.7 | -0.4 | -0.7 | -0.9 | 0.8 | -0.7 | -0.4 | -0.4 | 0.7 | 0.8 | -0.4 |
Time in open arm after self-admin | 0.4 | 0.4 | 1.5 | -0.5 | -0.5 | 0.4 | -1.2 | -0.6 | -0.5 | -0.3 | 0.5 | -0.5 | 0.6 | -0.6 | -0.4 | 0.7 | -0.6 | -0.6 | 0.7 | -0.7 | -0.6 | -0.7 | 0.7 | -0.8 | -0.5 | -0.7 | -0.5 | 0.6 | -0.5 | -0.4 | -1.1 | 1.0 | -0.7 | -0.6 | -0.5 | 0.5 | 0.7 | -0.5 |
Locomotion in novel chamber | 0.4 | 0.5 | 1.0 | 0.7 | 0.8 | -0.7 | 1.0 | 0.7 | 0.7 | 0.7 | -0.6 | 0.7 | -0.8 | 0.8 | 0.7 | -0.7 | 0.8 | 0.6 | -0.7 | 0.7 | 0.7 | 0.7 | -0.7 | 0.8 | 0.7 | 0.8 | 0.8 | -0.8 | 0.5 | 0.7 | 1.0 | -0.9 | 0.7 | 0.8 | 0.5 | -0.7 | -0.6 | 0.6 |
Run reversals in cocaine runway, females | 0.4 | 0.4 | 1.1 | -0.5 | -0.8 | 0.8 | 0.2 | -0.8 | -0.7 | -0.8 | 0.7 | -0.8 | 0.5 | -0.5 | -0.9 | 0.7 | -0.5 | -1.0 | 0.6 | -0.5 | -0.7 | -0.6 | 0.6 | -0.2 | -0.6 | -0.4 | -0.6 | 0.5 | -0.8 | -0.6 | 0.3 | 0.0 | -0.6 | -0.6 | -0.8 | 0.6 | 0.6 | -0.8 |
Cd content in liver | 0.4 | 0.4 | 1.0 | 0.5 | 0.9 | -0.9 | 0.3 | 0.9 | 0.6 | 0.7 | -0.7 | 0.8 | -0.5 | 0.5 | 0.8 | -0.6 | 0.6 | 1.0 | -0.6 | 0.6 | 0.7 | 0.6 | -0.6 | 0.3 | 0.5 | 0.5 | 0.7 | -0.5 | 0.7 | 0.5 | 0.3 | -0.4 | 0.6 | 0.8 | 0.7 | -0.6 | -0.6 | 0.7 |
Length without tail | 0.3 | 0.6 | 2.4 | 0.3 | 1.3 | -1.0 | 1.1 | 1.3 | 0.4 | 0.2 | -0.8 | 1.0 | -0.6 | 0.6 | 0.3 | -0.4 | 0.6 | 1.1 | -0.4 | 0.8 | 0.8 | 0.4 | -0.8 | 0.9 | 0.3 | 0.8 | 0.3 | -0.6 | 1.0 | 0.3 | 1.6 | -1.2 | 0.5 | 0.7 | 1.0 | -0.4 | -0.3 | 0.9 |
Locomotor testing distance | 0.3 | 0.5 | 1.0 | 0.9 | 0.8 | -0.8 | 0.2 | 0.9 | 0.8 | 1.0 | -0.7 | 0.9 | -0.6 | 0.6 | 1.0 | -0.7 | 0.6 | 1.0 | -0.5 | 0.5 | 0.7 | 0.9 | -0.5 | 0.4 | 0.9 | 0.5 | 0.8 | -0.6 | 0.7 | 0.9 | 0.0 | -0.1 | 0.6 | 0.9 | 0.7 | -0.8 | -0.9 | 0.7 |
Reaction time trials AUC | 0.3 | 0.4 | 0.9 | -0.4 | -0.7 | 0.4 | -1.0 | -0.8 | -0.5 | -0.4 | 0.5 | -0.5 | 0.5 | -0.6 | -0.5 | 0.6 | -0.6 | -0.6 | 0.5 | -0.6 | -0.5 | -0.8 | 0.7 | -0.6 | -0.4 | -0.6 | -0.5 | 0.6 | -0.6 | -0.4 | -1.0 | 0.9 | -0.7 | -0.7 | -0.6 | 0.5 | 0.8 | -0.5 |
Condit. Reinf. inactive responses | 0.3 | 0.4 | 2.6 | -0.4 | -0.9 | 0.4 | -1.2 | -0.9 | -0.3 | -0.1 | 0.5 | -0.6 | 0.6 | -0.6 | -0.2 | 0.3 | -0.6 | -0.4 | 0.4 | -0.7 | -0.5 | -0.3 | 0.7 | -1.0 | -0.4 | -0.8 | -0.4 | 0.6 | -0.4 | -0.4 | -1.6 | 1.3 | -0.4 | -0.7 | -0.4 | 0.3 | 0.3 | -0.4 |
Pavlov. Cond. lever contacts | 0.3 | 0.4 | 1.1 | -0.4 | -1.0 | 0.7 | -0.6 | -0.9 | -0.5 | -0.5 | 0.7 | -0.8 | 0.6 | -0.6 | -0.6 | 0.5 | -0.6 | -0.7 | 0.6 | -0.7 | -0.7 | -0.3 | 0.7 | -0.7 | -0.4 | -0.7 | -0.5 | 0.6 | -0.7 | -0.4 | -1.0 | 0.8 | -0.5 | -0.8 | -0.7 | 0.5 | 0.2 | -0.7 |
Locomotion distance, session 1 | 0.3 | 0.4 | 1.9 | -0.6 | -0.2 | 0.2 | -1.4 | -0.2 | -0.5 | -0.4 | 0.3 | -0.3 | 0.6 | -0.6 | -0.4 | 0.6 | -0.6 | -0.1 | 0.6 | -0.6 | -0.2 | -0.6 | 0.6 | -0.8 | -0.6 | -0.7 | -0.6 | 0.7 | -0.1 | -0.6 | -1.1 | 1.0 | -0.6 | -0.4 | -0.1 | 0.5 | 0.4 | -0.2 |
Degree of sensitization stereotypy | 0.3 | 0.3 | 0.8 | 0.6 | 0.2 | -0.6 | 0.9 | 0.3 | 0.5 | 0.5 | -0.6 | 0.5 | -0.6 | 0.6 | 0.4 | -0.5 | 0.5 | 0.5 | -0.5 | 0.5 | 0.7 | 0.7 | -0.5 | 0.6 | 0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.6 | 0.5 | -0.5 | 0.5 | 0.4 | 0.6 | -0.5 | -0.6 | 0.6 |
Time in familiar zone, hab. session 2 | 0.3 | 0.3 | 0.5 | 0.5 | 0.6 | -0.5 | 0.2 | 0.6 | 0.6 | 0.7 | -0.5 | 0.6 | -0.5 | 0.5 | 0.7 | -0.6 | 0.5 | 0.7 | -0.6 | 0.5 | 0.6 | 0.7 | -0.6 | 0.4 | 0.5 | 0.5 | 0.5 | -0.5 | 0.5 | 0.5 | 0.1 | -0.3 | 0.6 | 0.5 | 0.5 | -0.6 | -0.6 | 0.5 |
Total zone transitions, hab. session 2 | 0.3 | 0.4 | 0.8 | 0.6 | 0.8 | -0.8 | -0.0 | 0.7 | 0.5 | 0.6 | -0.8 | 0.8 | -0.5 | 0.5 | 0.6 | -0.4 | 0.5 | 0.9 | -0.4 | 0.5 | 0.9 | 0.5 | -0.5 | 0.4 | 0.6 | 0.4 | 0.6 | -0.5 | 0.9 | 0.6 | -0.0 | -0.1 | 0.4 | 0.6 | 0.9 | -0.6 | -0.6 | 0.8 |
Pavlov. Cond. lever contacts | 0.3 | 0.4 | 0.9 | -0.6 | -0.3 | 0.5 | -1.0 | -0.5 | -0.6 | -0.5 | 0.6 | -0.4 | 0.7 | -0.7 | -0.5 | 0.7 | -0.7 | -0.3 | 0.7 | -0.7 | -0.4 | -0.6 | 0.6 | -0.7 | -0.6 | -0.7 | -0.8 | 0.7 | -0.5 | -0.6 | -0.9 | 0.9 | -0.7 | -0.7 | -0.5 | 0.6 | 0.5 | -0.5 |
Bone: cortical thickness | 0.3 | 0.5 | 0.9 | 0.6 | 0.7 | -0.9 | 0.4 | 0.6 | 0.6 | 0.6 | -0.8 | 0.7 | -0.7 | 0.7 | 0.6 | -0.7 | 0.7 | 0.6 | -0.7 | 0.7 | 0.8 | 0.2 | -0.7 | 0.7 | 0.6 | 0.7 | 0.7 | -0.7 | 0.9 | 0.6 | 0.5 | -0.7 | 0.7 | 0.7 | 0.9 | -0.7 | -0.3 | 0.9 |
Bone: trabecular tissue density | 0.3 | 0.4 | 1.4 | -0.3 | -0.7 | 0.7 | -1.0 | -0.7 | -0.5 | -0.4 | 0.6 | -0.7 | 0.5 | -0.5 | -0.7 | 0.5 | -0.5 | -0.7 | 0.6 | -0.6 | -0.8 | -0.3 | 0.7 | -0.4 | -0.3 | -0.5 | -0.4 | 0.5 | -0.7 | -0.3 | -1.2 | 0.9 | -0.6 | -0.5 | -0.7 | 0.5 | 0.4 | -0.8 |
Sum of active levers in priming session hrs 5-6 | 0.3 | 0.3 | 0.6 | 0.2 | 0.7 | -0.7 | -0.3 | 0.7 | 0.5 | 0.7 | -0.6 | 0.6 | -0.3 | 0.3 | 0.7 | -0.6 | 0.3 | 0.7 | -0.5 | 0.4 | 0.8 | 0.7 | -0.5 | -0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.7 | 0.3 | -0.4 | 0.1 | 0.5 | 0.4 | 0.7 | -0.5 | -0.6 | 0.7 |
Time >=10cm from walls, locomotor time 1 | 0.3 | 0.3 | 0.7 | -0.7 | -0.4 | 0.6 | -0.1 | -0.6 | -0.7 | -0.9 | 0.7 | -0.7 | 0.6 | -0.5 | -0.8 | 0.6 | -0.5 | -0.6 | 0.6 | -0.4 | -0.6 | -0.6 | 0.4 | -0.2 | -0.7 | -0.4 | -0.7 | 0.5 | -0.7 | -0.7 | 0.0 | 0.1 | -0.6 | -0.5 | -0.7 | 0.7 | 0.6 | -0.7 |
Distance moved, locomotor task time 1 | 0.3 | 0.3 | 1.2 | 0.2 | 1.0 | -0.4 | 0.8 | 0.8 | 0.4 | 0.2 | -0.4 | 0.6 | -0.5 | 0.5 | 0.4 | -0.5 | 0.5 | 0.3 | -0.4 | 0.6 | 0.4 | 0.6 | -0.6 | 0.8 | 0.4 | 0.7 | 0.4 | -0.6 | 0.4 | 0.4 | 1.1 | -0.9 | 0.4 | 0.9 | 0.4 | -0.4 | -0.6 | 0.4 |
Vertical activity count, locomotor time 1 | 0.3 | 0.3 | 1.1 | 0.3 | 0.9 | -0.4 | 0.8 | 0.6 | 0.5 | 0.3 | -0.5 | 0.6 | -0.5 | 0.6 | 0.4 | -0.5 | 0.6 | 0.1 | -0.5 | 0.6 | 0.5 | 0.5 | -0.6 | 0.7 | 0.5 | 0.6 | 0.5 | -0.6 | 0.4 | 0.5 | 1.0 | -0.9 | 0.5 | 0.7 | 0.4 | -0.4 | -0.5 | 0.4 |
Vertical activity count, locomotor time 2 | 0.3 | 0.3 | 0.8 | -0.7 | -0.3 | 0.5 | 0.2 | -0.4 | -0.7 | -0.9 | 0.6 | -0.6 | 0.5 | -0.5 | -0.8 | 0.5 | -0.5 | -0.8 | 0.7 | -0.4 | -0.6 | -0.5 | 0.4 | -0.2 | -0.7 | -0.3 | -0.7 | 0.5 | -0.6 | -0.7 | 0.6 | -0.2 | -0.6 | -0.4 | -0.6 | 0.7 | 0.5 | -0.6 |
Weight adjusted by age | 0.3 | 0.4 | 1.1 | 0.6 | 0.1 | -0.8 | 0.0 | 0.2 | 0.7 | 0.9 | -0.6 | 0.6 | -0.5 | 0.5 | 0.7 | -0.6 | 0.5 | 0.3 | -0.8 | 0.5 | 0.8 | 1.0 | -0.6 | 0.1 | 0.6 | 0.4 | 0.5 | -0.5 | 0.7 | 0.6 | -0.6 | 0.1 | 0.8 | 0.2 | 0.7 | -0.7 | -0.8 | 0.8 |
Mn content in liver | 0.3 | 0.3 | 0.9 | 0.5 | 0.3 | -0.7 | -0.7 | 0.4 | 0.7 | 1.0 | -0.6 | 0.5 | -0.4 | 0.4 | 0.8 | -0.7 | 0.4 | 0.5 | -0.7 | 0.4 | 0.7 | 0.5 | -0.4 | -0.1 | 0.5 | 0.2 | 0.5 | -0.4 | 0.7 | 0.5 | -0.7 | 0.3 | 0.7 | 0.4 | 0.7 | -0.7 | -0.3 | 0.7 |
Glucose | 0.2 | 0.4 | 0.6 | 0.6 | 0.5 | -0.5 | 0.8 | 0.5 | 0.6 | 0.6 | -0.5 | 0.5 | -0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.4 | -0.6 | 0.6 | 0.4 | 0.8 | -0.6 | 0.6 | 0.6 | 0.6 | 0.6 | -0.6 | 0.4 | 0.6 | 0.7 | -0.6 | 0.7 | 0.6 | 0.4 | -0.6 | -0.8 | 0.5 |
Right kidney weight | 0.2 | 0.6 | 2.5 | 0.5 | 1.1 | -0.6 | 1.1 | 0.9 | 0.3 | -0.0 | -0.7 | 0.8 | -0.6 | 0.7 | 0.0 | -0.3 | 0.7 | 0.9 | -0.3 | 0.8 | 0.7 | -0.1 | -0.7 | 1.3 | 0.5 | 0.9 | 0.4 | -0.7 | 0.7 | 0.5 | 1.6 | -1.4 | 0.4 | 0.6 | 0.7 | -0.4 | -0.0 | 0.6 |
Length with tail | 0.2 | 0.8 | 3.6 | 0.3 | 1.2 | -0.9 | 1.6 | 1.1 | 0.4 | 0.0 | -0.8 | 0.9 | -0.7 | 0.8 | 0.1 | -0.6 | 0.7 | 0.9 | -0.6 | 1.0 | 0.7 | 0.5 | -1.0 | 1.4 | 0.3 | 1.1 | 0.6 | -0.8 | 1.0 | 0.4 | 1.9 | -1.7 | 0.5 | 0.9 | 1.0 | -0.4 | -0.5 | 0.9 |
Delay discounting time to switch 0 sec | 0.2 | 0.3 | 0.7 | 0.6 | 0.5 | -0.4 | -0.0 | 0.6 | 0.6 | 0.7 | -0.5 | 0.4 | -0.5 | 0.5 | 0.7 | -0.6 | 0.5 | 0.7 | -0.5 | 0.5 | 0.4 | 0.8 | -0.5 | 0.3 | 0.6 | 0.4 | 0.7 | -0.5 | 0.4 | 0.6 | -0.2 | -0.1 | 0.6 | 0.6 | 0.4 | -0.6 | -0.9 | 0.4 |
Delay discounting water rate 24 sec | 0.2 | 0.2 | 1.0 | 0.3 | 0.7 | -0.4 | 0.6 | 0.5 | 0.2 | -0.0 | -0.4 | 0.5 | -0.5 | 0.5 | 0.0 | -0.3 | 0.5 | 0.6 | -0.4 | 0.6 | 0.2 | 0.0 | -0.6 | 1.0 | 0.4 | 0.7 | 0.3 | -0.5 | 0.4 | 0.4 | 0.9 | -0.9 | 0.3 | 0.4 | 0.4 | -0.3 | 0.0 | 0.4 |
Reaction time number correct | 0.2 | 0.3 | 0.6 | -0.3 | -0.6 | 0.4 | -0.8 | -0.7 | -0.4 | -0.4 | 0.5 | -0.5 | 0.5 | -0.5 | -0.4 | 0.6 | -0.5 | -0.5 | 0.5 | -0.6 | -0.5 | -0.8 | 0.6 | -0.5 | -0.4 | -0.5 | -0.5 | 0.5 | -0.5 | -0.3 | -0.7 | 0.7 | -0.6 | -0.6 | -0.5 | 0.4 | 0.8 | -0.5 |
Reaction time trials correct on left | 0.2 | 0.3 | 0.6 | -0.3 | -0.6 | 0.4 | -0.8 | -0.7 | -0.4 | -0.4 | 0.5 | -0.5 | 0.5 | -0.5 | -0.4 | 0.6 | -0.5 | -0.5 | 0.5 | -0.6 | -0.5 | -0.8 | 0.6 | -0.5 | -0.4 | -0.5 | -0.5 | 0.5 | -0.5 | -0.3 | -0.7 | 0.7 | -0.6 | -0.6 | -0.5 | 0.4 | 0.8 | -0.5 |
Reaction time trials on left | 0.2 | 0.3 | 0.6 | -0.3 | -0.6 | 0.4 | -0.8 | -0.7 | -0.4 | -0.3 | 0.4 | -0.5 | 0.5 | -0.5 | -0.4 | 0.6 | -0.5 | -0.5 | 0.5 | -0.6 | -0.5 | -0.8 | 0.6 | -0.5 | -0.3 | -0.5 | -0.4 | 0.5 | -0.5 | -0.3 | -0.8 | 0.7 | -0.6 | -0.6 | -0.5 | 0.4 | 0.8 | -0.5 |
Reaction time premature initiation rate | 0.2 | 0.2 | 0.5 | 0.3 | 0.3 | -0.5 | 0.5 | 0.4 | 0.4 | 0.4 | -0.5 | 0.4 | -0.4 | 0.5 | 0.4 | -0.5 | 0.4 | 0.5 | -0.4 | 0.5 | 0.4 | 0.7 | -0.5 | 0.5 | 0.3 | 0.5 | 0.5 | -0.5 | 0.5 | 0.4 | 0.3 | -0.4 | 0.5 | 0.5 | 0.5 | -0.4 | -0.7 | 0.4 |
Reaction time trials completed | 0.2 | 0.3 | 0.6 | -0.3 | -0.6 | 0.4 | -0.8 | -0.7 | -0.4 | -0.3 | 0.4 | -0.5 | 0.5 | -0.5 | -0.4 | 0.6 | -0.5 | -0.5 | 0.5 | -0.6 | -0.5 | -0.8 | 0.6 | -0.5 | -0.3 | -0.5 | -0.4 | 0.5 | -0.5 | -0.3 | -0.8 | 0.7 | -0.6 | -0.6 | -0.5 | 0.4 | 0.8 | -0.5 |
Social response proportion | 0.2 | 0.2 | 1.0 | -0.2 | -0.5 | 0.4 | 1.0 | -0.5 | -0.4 | -0.7 | 0.4 | -0.4 | 0.3 | -0.3 | -0.5 | 0.5 | -0.3 | -0.4 | 0.6 | -0.3 | -0.4 | -0.6 | 0.4 | -0.0 | -0.3 | -0.1 | -0.4 | 0.2 | -0.5 | -0.3 | 1.0 | -0.4 | -0.6 | -0.4 | -0.5 | 0.4 | 0.6 | -0.4 |
Cocaine response after cond. corrected | 0.2 | 0.2 | 0.3 | -0.4 | -0.4 | 0.4 | 0.0 | -0.4 | -0.4 | -0.4 | 0.4 | -0.4 | 0.4 | -0.4 | -0.3 | 0.5 | -0.4 | -0.5 | 0.4 | -0.5 | -0.4 | -0.4 | 0.5 | -0.5 | -0.4 | -0.5 | -0.5 | 0.4 | -0.4 | -0.4 | 0.1 | 0.2 | -0.5 | -0.4 | -0.4 | 0.4 | 0.6 | -0.4 |
Pavlov. Cond. lever-magazine prob. diff. | 0.2 | 0.2 | 1.3 | -0.2 | -0.8 | 0.4 | -0.7 | -0.7 | -0.2 | -0.1 | 0.4 | -0.5 | 0.3 | -0.3 | -0.3 | 0.2 | -0.3 | -0.6 | 0.2 | -0.4 | -0.4 | -0.0 | 0.4 | -0.5 | -0.2 | -0.4 | -0.3 | 0.4 | -0.5 | -0.2 | -1.1 | 0.8 | -0.2 | -0.5 | -0.5 | 0.2 | -0.1 | -0.4 |
Context. condit. distance diff. score | 0.2 | 0.2 | 0.4 | -0.5 | -0.5 | 0.4 | -0.1 | -0.4 | -0.6 | -0.7 | 0.5 | -0.5 | 0.5 | -0.4 | -0.7 | 0.5 | -0.5 | -0.2 | 0.5 | -0.4 | -0.4 | -0.5 | 0.4 | -0.2 | -0.5 | -0.3 | -0.5 | 0.4 | -0.4 | -0.5 | -0.1 | 0.1 | -0.5 | -0.5 | -0.4 | 0.5 | 0.6 | -0.4 |
Locomotion distance, session 8 | 0.2 | 0.3 | 0.6 | -0.6 | -0.7 | 0.4 | -0.4 | -0.6 | -0.7 | -0.7 | 0.5 | -0.5 | 0.6 | -0.6 | -0.8 | 0.7 | -0.6 | -0.3 | 0.7 | -0.6 | -0.5 | -0.6 | 0.6 | -0.5 | -0.6 | -0.6 | -0.6 | 0.6 | -0.4 | -0.6 | -0.5 | 0.5 | -0.7 | -0.7 | -0.4 | 0.6 | 0.6 | -0.4 |
Incentive salience index mean | 0.2 | 0.2 | 0.6 | 0.5 | 0.7 | -0.5 | 0.5 | 0.6 | 0.5 | 0.6 | -0.5 | 0.6 | -0.5 | 0.4 | 0.7 | -0.4 | 0.5 | 0.6 | -0.4 | 0.4 | 0.5 | 0.5 | -0.4 | 0.3 | 0.5 | 0.4 | 0.6 | -0.4 | 0.5 | 0.5 | 0.5 | -0.4 | 0.4 | 0.6 | 0.5 | -0.5 | -0.5 | 0.5 |
Time in novel zone, hab. session 1 | 0.2 | 0.2 | 0.4 | 0.5 | 0.1 | -0.5 | 0.3 | 0.2 | 0.5 | 0.5 | -0.4 | 0.4 | -0.4 | 0.4 | 0.4 | -0.5 | 0.4 | 0.3 | -0.5 | 0.4 | 0.4 | 0.6 | -0.4 | 0.4 | 0.5 | 0.4 | 0.5 | -0.4 | 0.4 | 0.5 | -0.0 | -0.2 | 0.5 | 0.3 | 0.4 | -0.5 | -0.5 | 0.4 |
Total locomotion distance, hab. session 2 | 0.2 | 0.3 | 0.5 | 0.6 | 0.3 | -0.6 | -0.1 | 0.4 | 0.6 | 0.7 | -0.6 | 0.5 | -0.5 | 0.5 | 0.6 | -0.5 | 0.5 | 0.6 | -0.6 | 0.4 | 0.6 | 0.4 | -0.5 | 0.3 | 0.6 | 0.4 | 0.5 | -0.5 | 0.6 | 0.6 | -0.3 | 0.0 | 0.6 | 0.4 | 0.6 | -0.6 | -0.6 | 0.6 |
Bone: stiffness | 0.2 | 0.3 | 0.6 | 0.4 | 0.7 | -0.8 | -0.2 | 0.7 | 0.4 | 0.4 | -0.6 | 0.6 | -0.4 | 0.4 | 0.4 | -0.5 | 0.4 | 0.7 | -0.4 | 0.5 | 0.7 | 0.1 | -0.5 | 0.4 | 0.4 | 0.4 | 0.4 | -0.4 | 0.8 | 0.4 | 0.1 | -0.3 | 0.5 | 0.6 | 0.8 | -0.4 | -0.3 | 0.7 |
Distance traveled before self-admin | 0.2 | 0.3 | 0.7 | -0.2 | -0.8 | 0.6 | 0.2 | -0.9 | -0.4 | -0.6 | 0.5 | -0.6 | 0.3 | -0.3 | -0.7 | 0.6 | -0.4 | -0.8 | 0.6 | -0.5 | -0.8 | -0.6 | 0.6 | -0.0 | -0.1 | -0.3 | -0.1 | 0.3 | -0.7 | -0.2 | 0.0 | 0.1 | -0.6 | -0.4 | -0.7 | 0.4 | 0.3 | -0.7 |
Time in closed arm before self-admin | 0.2 | 0.2 | 0.4 | 0.6 | 0.4 | -0.1 | 0.3 | 0.5 | 0.4 | 0.3 | -0.4 | 0.4 | -0.5 | 0.5 | 0.3 | -0.3 | 0.5 | 0.5 | -0.4 | 0.4 | 0.3 | 0.4 | -0.4 | 0.6 | 0.6 | 0.5 | 0.6 | -0.5 | 0.3 | 0.4 | 0.3 | -0.4 | 0.4 | 0.5 | 0.3 | -0.4 | -0.5 | 0.2 |
Ambulatory time before self-admin | 0.2 | 0.2 | 0.6 | -0.2 | -0.7 | 0.5 | -0.0 | -0.8 | -0.4 | -0.5 | 0.4 | -0.5 | 0.3 | -0.3 | -0.6 | 0.6 | -0.3 | -0.6 | 0.6 | -0.5 | -0.7 | -0.3 | 0.6 | -0.1 | -0.1 | -0.3 | -0.1 | 0.3 | -0.6 | -0.1 | -0.3 | 0.4 | -0.6 | -0.4 | -0.6 | 0.4 | 0.2 | -0.6 |
Ambulatory time after self-admin | 0.2 | 0.2 | 1.2 | 0.3 | 0.3 | -0.4 | 1.1 | 0.3 | 0.2 | 0.0 | -0.4 | 0.4 | -0.4 | 0.4 | 0.1 | -0.2 | 0.4 | 0.5 | -0.1 | 0.4 | 0.3 | 0.3 | -0.3 | 0.7 | 0.4 | 0.5 | 0.4 | -0.4 | 0.3 | 0.3 | 0.9 | -0.7 | 0.1 | 0.4 | 0.3 | -0.2 | -0.5 | 0.3 |
Delay disc. indifference point, 2s delay | 0.2 | 0.2 | 0.9 | 0.3 | 0.2 | -0.5 | 1.0 | 0.3 | 0.3 | 0.2 | -0.4 | 0.3 | -0.4 | 0.4 | 0.2 | -0.4 | 0.4 | 0.2 | -0.4 | 0.5 | 0.5 | 0.3 | -0.4 | 0.5 | 0.4 | 0.5 | 0.3 | -0.4 | 0.5 | 0.4 | 1.0 | -0.8 | 0.4 | 0.3 | 0.5 | -0.3 | -0.3 | 0.5 |
Delay disc. indifference point, 4s delay | 0.2 | 0.2 | 0.7 | 0.5 | 0.4 | -0.4 | 0.7 | 0.4 | 0.6 | 0.5 | -0.4 | 0.4 | -0.5 | 0.5 | 0.6 | -0.5 | 0.5 | 0.2 | -0.5 | 0.5 | 0.4 | 0.3 | -0.4 | 0.4 | 0.5 | 0.5 | 0.4 | -0.5 | 0.4 | 0.5 | 0.8 | -0.6 | 0.5 | 0.5 | 0.4 | -0.5 | -0.3 | 0.4 |
Total resting periods, locomotor time 1 | 0.2 | 0.2 | 1.5 | -0.1 | -0.8 | -0.1 | -0.5 | -0.8 | -0.0 | 0.3 | 0.1 | -0.2 | 0.3 | -0.3 | -0.0 | 0.0 | -0.3 | -0.1 | 0.0 | -0.4 | -0.0 | 0.1 | 0.3 | -0.8 | -0.1 | -0.5 | -0.1 | 0.3 | -0.0 | -0.1 | -1.2 | 1.0 | 0.0 | -0.7 | -0.0 | 0.0 | -0.1 | -0.0 |
Latency to leave start box in cocaine runway, F | 0.2 | 0.2 | 0.4 | -0.4 | -0.7 | 0.5 | -0.3 | -0.5 | -0.3 | -0.2 | 0.5 | -0.5 | 0.4 | -0.4 | -0.3 | 0.2 | -0.4 | -0.6 | 0.3 | -0.4 | -0.5 | -0.2 | 0.4 | -0.5 | -0.3 | -0.5 | -0.3 | 0.4 | -0.6 | -0.3 | -0.5 | 0.5 | -0.3 | -0.4 | -0.6 | 0.3 | 0.2 | -0.5 |
Sr content in liver | 0.2 | 0.1 | 1.9 | 0.2 | -0.1 | 0.0 | 1.4 | -0.1 | 0.2 | 0.0 | -0.1 | 0.0 | -0.3 | 0.3 | 0.1 | -0.2 | 0.3 | -0.1 | -0.2 | 0.3 | -0.0 | 0.5 | -0.2 | 0.4 | 0.2 | 0.3 | 0.2 | -0.3 | -0.0 | 0.2 | 1.0 | -0.7 | 0.2 | 0.1 | -0.0 | -0.2 | -0.3 | -0.0 |
Tail length | 0.1 | 0.4 | 0.9 | -0.8 | -0.7 | 0.7 | -0.1 | -0.7 | -0.8 | -0.9 | 0.7 | -0.8 | 0.6 | -0.6 | -0.9 | 0.6 | -0.6 | -0.8 | 0.6 | -0.5 | -0.8 | -0.7 | 0.5 | -0.2 | -0.7 | -0.4 | -0.5 | 0.5 | -0.6 | -0.7 | -0.1 | 0.1 | -0.6 | -0.4 | -0.6 | 0.8 | 0.6 | -0.7 |
Food consumed during 24 hour testing period | 0.1 | 0.1 | 0.4 | 0.2 | 0.1 | -0.3 | 0.5 | 0.2 | 0.3 | 0.4 | -0.2 | 0.3 | -0.3 | 0.2 | 0.3 | -0.4 | 0.3 | 0.3 | -0.4 | 0.3 | 0.2 | 0.6 | -0.3 | 0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.2 | 0.2 | 0.2 | -0.2 | 0.4 | 0.1 | 0.2 | -0.3 | -0.6 | 0.2 |
Indifference point AUC | 0.1 | 0.2 | 1.8 | 0.1 | -0.1 | -0.0 | -1.4 | -0.1 | 0.2 | 0.5 | -0.1 | -0.1 | 0.1 | -0.2 | 0.4 | -0.2 | -0.1 | -0.3 | -0.2 | -0.2 | 0.1 | -0.2 | 0.1 | -0.7 | 0.1 | -0.4 | -0.0 | 0.2 | 0.0 | 0.2 | -1.3 | 0.9 | 0.2 | -0.0 | 0.0 | -0.1 | 0.1 | 0.1 |
Delay discounting water rate 12 sec | 0.1 | 0.1 | 0.8 | 0.3 | 0.4 | -0.4 | 0.3 | 0.2 | 0.1 | -0.1 | -0.3 | 0.4 | -0.4 | 0.4 | -0.2 | -0.2 | 0.4 | 0.4 | -0.1 | 0.4 | 0.2 | 0.1 | -0.4 | 0.9 | 0.3 | 0.6 | 0.4 | -0.4 | 0.3 | 0.3 | 0.3 | -0.5 | 0.1 | 0.3 | 0.3 | -0.2 | -0.2 | 0.2 |
Delay discounting water rate 6 sec | 0.1 | 0.2 | 0.8 | -0.4 | -0.2 | 0.2 | 0.8 | -0.3 | -0.5 | -0.9 | 0.2 | -0.3 | 0.2 | -0.1 | -0.9 | 0.3 | -0.2 | -0.3 | 0.3 | -0.0 | -0.3 | -0.2 | 0.1 | 0.5 | -0.4 | 0.1 | -0.5 | 0.1 | -0.2 | -0.4 | 0.8 | -0.6 | -0.4 | -0.3 | -0.2 | 0.5 | 0.3 | -0.2 |
Reaction time mean minus median | 0.1 | 0.1 | 0.4 | 0.1 | -0.7 | 0.5 | 0.2 | -0.5 | 0.0 | 0.0 | 0.4 | -0.4 | 0.0 | -0.0 | -0.1 | -0.1 | -0.0 | -0.3 | -0.1 | -0.1 | -0.4 | 0.0 | 0.1 | -0.1 | 0.1 | -0.1 | 0.1 | 0.0 | -0.5 | -0.0 | -0.2 | 0.1 | 0.2 | -0.2 | -0.5 | -0.0 | -0.1 | -0.4 |
Reaction time mean | 0.1 | 0.1 | 0.8 | 0.2 | -0.3 | 0.3 | 0.9 | -0.1 | 0.0 | -0.2 | 0.1 | -0.1 | -0.3 | 0.3 | -0.2 | -0.3 | 0.3 | -0.1 | -0.2 | 0.3 | -0.1 | 0.2 | -0.3 | 0.7 | 0.2 | 0.5 | 0.2 | -0.3 | -0.2 | 0.1 | 0.7 | -0.7 | 0.3 | 0.1 | -0.2 | -0.1 | -0.2 | -0.1 |
Reaction time mean AUC | 0.1 | 0.1 | 0.8 | 0.1 | -0.4 | 0.3 | 0.9 | -0.2 | -0.1 | -0.3 | 0.2 | -0.2 | -0.1 | 0.2 | -0.3 | -0.2 | 0.1 | -0.2 | -0.1 | 0.2 | -0.2 | 0.0 | -0.1 | 0.6 | 0.1 | 0.3 | 0.1 | -0.2 | -0.3 | 0.0 | 0.7 | -0.7 | 0.2 | -0.0 | -0.3 | 0.0 | -0.1 | -0.2 |
Median of all reaction times | 0.1 | 0.1 | 0.8 | 0.0 | -0.2 | 0.2 | 0.9 | -0.1 | -0.1 | -0.4 | 0.1 | -0.1 | -0.2 | 0.2 | -0.4 | -0.2 | 0.2 | -0.2 | -0.0 | 0.3 | -0.1 | -0.0 | -0.2 | 0.7 | 0.0 | 0.4 | 0.1 | -0.2 | -0.2 | -0.0 | 0.8 | -0.8 | 0.1 | 0.1 | -0.2 | 0.1 | -0.1 | -0.1 |
Reaction time omissions | 0.1 | 0.2 | 0.5 | 0.5 | 0.5 | -0.4 | 0.3 | 0.5 | 0.5 | 0.6 | -0.5 | 0.5 | -0.4 | 0.4 | 0.7 | -0.3 | 0.4 | 0.4 | -0.3 | 0.2 | 0.4 | 0.3 | -0.2 | 0.1 | 0.6 | 0.3 | 0.6 | -0.4 | 0.4 | 0.5 | 0.3 | -0.2 | 0.3 | 0.6 | 0.4 | -0.5 | -0.4 | 0.4 |
Std. dev. reaction times | 0.1 | 0.2 | 0.5 | 0.6 | -0.2 | 0.1 | 0.7 | -0.1 | 0.4 | 0.4 | -0.1 | 0.1 | -0.5 | 0.5 | 0.2 | -0.5 | 0.5 | 0.1 | -0.5 | 0.4 | 0.0 | 0.5 | -0.3 | 0.6 | 0.6 | 0.5 | 0.6 | -0.5 | -0.1 | 0.5 | 0.3 | -0.5 | 0.5 | 0.3 | -0.1 | -0.4 | -0.5 | -0.0 |
Social responses | 0.1 | 0.2 | 0.4 | 0.4 | 0.2 | -0.5 | 0.6 | 0.3 | 0.4 | 0.3 | -0.4 | 0.5 | -0.4 | 0.4 | 0.4 | -0.3 | 0.4 | 0.5 | -0.2 | 0.4 | 0.5 | 0.1 | -0.4 | 0.4 | 0.4 | 0.4 | 0.3 | -0.4 | 0.5 | 0.4 | 0.5 | -0.4 | 0.3 | 0.3 | 0.5 | -0.4 | -0.2 | 0.6 |
Social time | 0.1 | 0.1 | 0.5 | -0.2 | -0.3 | 0.3 | 0.2 | -0.4 | -0.4 | -0.6 | 0.4 | -0.3 | 0.3 | -0.2 | -0.6 | 0.5 | -0.3 | -0.2 | 0.4 | -0.2 | -0.4 | -0.7 | 0.3 | 0.1 | -0.2 | -0.1 | -0.3 | 0.2 | -0.4 | -0.2 | 0.3 | -0.2 | -0.4 | -0.4 | -0.4 | 0.4 | 0.6 | -0.3 |
Pavlov. Cond. change in total contacts | 0.1 | 0.1 | 0.9 | 0.1 | -0.7 | 0.3 | -0.6 | -0.6 | -0.1 | 0.0 | 0.3 | -0.4 | 0.2 | -0.2 | -0.2 | 0.1 | -0.2 | -0.6 | 0.2 | -0.3 | -0.3 | -0.1 | 0.4 | -0.4 | 0.1 | -0.3 | -0.2 | 0.2 | -0.4 | 0.1 | -1.0 | 0.7 | -0.2 | -0.5 | -0.4 | 0.1 | 0.1 | -0.3 |
Pavlov. Cond. magazine entry number | 0.1 | 0.1 | 0.4 | -0.4 | 0.0 | 0.1 | 0.1 | -0.0 | -0.4 | -0.5 | 0.2 | -0.1 | 0.3 | -0.3 | -0.3 | 0.4 | -0.3 | -0.1 | 0.4 | -0.2 | -0.1 | -0.5 | 0.2 | -0.1 | -0.4 | -0.2 | -0.3 | 0.3 | -0.1 | -0.4 | 0.4 | -0.1 | -0.4 | -0.1 | -0.1 | 0.4 | 0.6 | -0.2 |
Intermittent access intake escalation 2 | 0.1 | 0.1 | 0.3 | 0.2 | 0.4 | -0.1 | 0.2 | 0.3 | 0.1 | 0.0 | -0.2 | 0.3 | -0.2 | 0.3 | 0.0 | -0.1 | 0.2 | 0.6 | -0.1 | 0.2 | 0.0 | 0.1 | -0.2 | 0.4 | 0.2 | 0.3 | 0.2 | -0.3 | 0.3 | 0.2 | 0.3 | -0.4 | 0.1 | 0.3 | 0.3 | -0.2 | 0.2 | 0.2 |
Intermitt. access day 1 inactive lever presses | 0.1 | 0.1 | 0.8 | -0.2 | -0.4 | 0.2 | -0.9 | -0.1 | -0.1 | -0.1 | 0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.3 | -0.2 | 0.0 | 0.1 | -0.2 | -0.3 | -0.5 | 0.2 | -0.3 | -0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.2 | -0.8 | 0.5 | -0.1 | -0.3 | -0.2 | 0.1 | 0.4 | -0.2 |
Cocaine induced anxiety | 0.1 | 0.1 | 0.8 | -0.2 | 0.1 | 0.1 | -0.9 | 0.0 | -0.2 | -0.0 | 0.1 | -0.2 | 0.2 | -0.3 | -0.0 | 0.2 | -0.2 | -0.5 | 0.1 | -0.2 | -0.1 | -0.2 | 0.2 | -0.4 | -0.2 | -0.3 | -0.2 | 0.3 | -0.1 | -0.2 | -0.7 | 0.6 | -0.1 | -0.1 | -0.1 | 0.2 | 0.1 | -0.1 |
Short access day 10 total inactive lever presses | 0.1 | 0.1 | 1.2 | 0.3 | -0.4 | -0.4 | -0.8 | 0.2 | 0.4 | 0.6 | -0.3 | 0.2 | -0.1 | 0.1 | 0.4 | -0.2 | 0.1 | 0.5 | -0.2 | -0.0 | 0.3 | 0.3 | -0.0 | -0.4 | 0.3 | -0.1 | 0.2 | -0.1 | 0.4 | 0.3 | -1.1 | 0.7 | 0.2 | -0.0 | 0.4 | -0.4 | -0.2 | 0.3 |
Locomotion velocity, session 2 | 0.1 | 0.1 | 0.3 | 0.1 | 0.5 | -0.4 | 0.4 | 0.3 | 0.1 | -0.0 | -0.3 | 0.4 | -0.2 | 0.2 | -0.0 | -0.1 | 0.2 | 0.3 | -0.1 | 0.2 | 0.4 | 0.1 | -0.2 | 0.4 | 0.1 | 0.3 | 0.2 | -0.2 | 0.4 | 0.1 | 0.4 | -0.4 | 0.1 | 0.2 | 0.4 | -0.1 | -0.2 | 0.3 |
Locomotion distance, session 2 | 0.1 | 0.2 | 0.6 | 0.4 | 0.7 | -0.7 | -0.1 | 0.6 | 0.3 | 0.4 | -0.6 | 0.6 | -0.3 | 0.3 | 0.4 | -0.2 | 0.3 | 0.7 | -0.3 | 0.3 | 0.7 | 0.1 | -0.4 | 0.3 | 0.4 | 0.3 | 0.3 | -0.3 | 0.8 | 0.4 | -0.0 | -0.1 | 0.3 | 0.4 | 0.8 | -0.4 | -0.3 | 0.6 |
Locomotion velocity, session 3 | 0.1 | 0.2 | 1.6 | -0.1 | -0.5 | 0.1 | -1.0 | -0.5 | -0.1 | 0.1 | 0.1 | -0.3 | 0.3 | -0.3 | -0.1 | 0.2 | -0.3 | -0.2 | 0.2 | -0.4 | -0.1 | -0.3 | 0.4 | -0.6 | -0.1 | -0.5 | -0.2 | 0.3 | -0.1 | -0.1 | -1.3 | 0.9 | -0.2 | -0.4 | -0.1 | 0.1 | 0.2 | -0.1 |
Locomotion distance, session 3 | 0.1 | 0.1 | 1.1 | 0.2 | 0.2 | -0.4 | -1.0 | 0.2 | 0.3 | 0.5 | -0.3 | 0.3 | -0.1 | 0.1 | 0.4 | -0.2 | 0.1 | 0.5 | -0.2 | 0.0 | 0.3 | 0.0 | -0.1 | -0.3 | 0.2 | -0.1 | 0.2 | -0.0 | 0.4 | 0.2 | -1.0 | 0.7 | 0.2 | 0.1 | 0.4 | -0.3 | -0.1 | 0.4 |
Locomotion velocity, session 7 | 0.1 | 0.1 | 0.7 | 0.1 | -0.3 | -0.0 | -0.6 | -0.2 | 0.2 | 0.4 | -0.1 | -0.1 | -0.0 | -0.0 | 0.3 | -0.2 | 0.0 | 0.1 | -0.2 | -0.1 | 0.0 | 0.1 | 0.1 | -0.3 | 0.1 | -0.2 | 0.1 | 0.0 | 0.0 | 0.1 | -0.8 | 0.6 | 0.2 | -0.1 | 0.0 | -0.2 | -0.1 | 0.1 |
Condit. Reinf. active responses | 0.1 | 0.1 | 0.3 | 0.4 | 0.5 | -0.3 | 0.4 | 0.4 | 0.4 | 0.5 | -0.4 | 0.4 | -0.3 | 0.3 | 0.5 | -0.3 | 0.3 | 0.4 | -0.3 | 0.3 | 0.4 | 0.4 | -0.3 | 0.2 | 0.4 | 0.3 | 0.5 | -0.3 | 0.3 | 0.4 | 0.4 | -0.2 | 0.3 | 0.5 | 0.3 | -0.4 | -0.4 | 0.3 |
Total zone transitions, hab. session 1 | 0.1 | 0.2 | 0.3 | -0.4 | -0.1 | 0.3 | -0.5 | -0.3 | -0.5 | -0.5 | 0.3 | -0.3 | 0.4 | -0.4 | -0.5 | 0.6 | -0.4 | -0.3 | 0.5 | -0.4 | -0.3 | -0.6 | 0.4 | -0.2 | -0.4 | -0.3 | -0.3 | 0.4 | -0.3 | -0.4 | -0.3 | 0.3 | -0.5 | -0.3 | -0.3 | 0.4 | 0.6 | -0.3 |
Locomotion velocity, hab. session 2 | 0.1 | 0.1 | 0.3 | 0.4 | 0.1 | -0.4 | -0.3 | 0.2 | 0.4 | 0.6 | -0.4 | 0.4 | -0.3 | 0.3 | 0.4 | -0.4 | 0.3 | 0.4 | -0.4 | 0.3 | 0.4 | 0.2 | -0.3 | 0.1 | 0.4 | 0.2 | 0.4 | -0.3 | 0.4 | 0.4 | -0.5 | 0.2 | 0.4 | 0.2 | 0.4 | -0.4 | -0.4 | 0.5 |
Pavlov. Cond. magazine entry latency | 0.1 | 0.1 | 0.3 | 0.2 | 0.5 | -0.3 | -0.1 | 0.4 | 0.3 | 0.3 | -0.3 | 0.5 | -0.2 | 0.2 | 0.3 | -0.2 | 0.2 | 0.6 | -0.2 | 0.2 | 0.3 | 0.3 | -0.3 | 0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.3 | 0.2 | -0.1 | 0.0 | 0.2 | 0.2 | 0.3 | -0.3 | -0.3 | 0.2 |
Pavlov. Cond. index score | 0.1 | 0.1 | 0.6 | -0.2 | 0.2 | 0.0 | -0.8 | 0.0 | -0.1 | -0.0 | 0.1 | 0.1 | 0.2 | -0.2 | -0.0 | 0.2 | -0.2 | 0.2 | 0.2 | -0.3 | 0.1 | -0.1 | 0.2 | -0.4 | -0.2 | -0.3 | -0.3 | 0.3 | -0.0 | -0.2 | -0.7 | 0.6 | -0.2 | -0.2 | -0.0 | 0.1 | 0.1 | -0.1 |
Pavlov. Cond. latency score | 0.1 | 0.1 | 0.7 | -0.0 | 0.4 | -0.1 | -0.8 | 0.2 | 0.0 | 0.2 | -0.1 | 0.3 | 0.1 | -0.1 | 0.2 | 0.1 | -0.1 | 0.4 | 0.1 | -0.1 | 0.3 | -0.0 | 0.1 | -0.3 | -0.0 | -0.2 | -0.2 | 0.1 | 0.2 | -0.0 | -0.7 | 0.6 | -0.1 | -0.0 | 0.2 | -0.0 | -0.0 | 0.1 |
Bone: cortical apparent density | 0.1 | 0.1 | 1.5 | -0.0 | -0.1 | 0.4 | -1.2 | -0.2 | -0.1 | -0.0 | 0.2 | -0.3 | 0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.4 | 0.2 | -0.3 | -0.4 | -0.3 | 0.3 | -0.2 | -0.0 | -0.2 | -0.0 | 0.2 | -0.3 | -0.0 | -1.0 | 0.7 | -0.2 | -0.1 | -0.3 | 0.1 | 0.3 | -0.4 |
Bone: cortical area | 0.1 | 0.2 | 0.5 | 0.2 | 0.6 | -0.7 | -0.7 | 0.5 | 0.3 | 0.4 | -0.5 | 0.4 | -0.2 | 0.2 | 0.4 | -0.3 | 0.2 | 0.5 | -0.3 | 0.3 | 0.6 | -0.3 | -0.3 | 0.0 | 0.2 | 0.2 | 0.2 | -0.2 | 0.7 | 0.2 | -0.3 | 0.1 | 0.3 | 0.4 | 0.7 | -0.3 | 0.1 | 0.6 |
Bone: cortical tissue density | 0.1 | 0.1 | 1.2 | 0.0 | 0.0 | 0.3 | -1.1 | -0.1 | -0.0 | 0.0 | 0.1 | -0.2 | 0.1 | -0.1 | -0.1 | 0.1 | -0.1 | -0.2 | 0.1 | -0.2 | -0.3 | -0.1 | 0.2 | -0.1 | 0.0 | -0.1 | 0.0 | 0.1 | -0.2 | 0.0 | -0.9 | 0.5 | -0.1 | 0.0 | -0.2 | 0.0 | 0.2 | -0.3 |
Bone: endosteal estimation | 0.1 | 0.2 | 1.2 | -0.4 | 0.2 | 0.2 | -1.1 | 0.1 | -0.3 | -0.1 | 0.2 | -0.1 | 0.4 | -0.4 | -0.0 | 0.3 | -0.4 | 0.1 | 0.2 | -0.3 | -0.2 | -0.3 | 0.2 | -0.6 | -0.4 | -0.5 | -0.4 | 0.4 | -0.2 | -0.4 | -0.8 | 0.7 | -0.3 | -0.1 | -0.2 | 0.3 | 0.3 | -0.1 |
Bone: marrow area | 0.1 | 0.2 | 1.2 | -0.4 | 0.1 | 0.3 | -1.1 | 0.1 | -0.3 | -0.2 | 0.3 | -0.1 | 0.4 | -0.4 | -0.1 | 0.3 | -0.4 | 0.1 | 0.3 | -0.4 | -0.2 | -0.3 | 0.3 | -0.6 | -0.4 | -0.5 | -0.4 | 0.5 | -0.2 | -0.4 | -0.8 | 0.7 | -0.3 | -0.2 | -0.2 | 0.3 | 0.3 | -0.2 |
Bone: maximum diameter | 0.1 | 0.1 | 1.3 | -0.1 | 0.3 | -0.3 | -1.2 | 0.3 | 0.1 | 0.3 | -0.2 | 0.2 | 0.1 | -0.1 | 0.3 | -0.1 | -0.1 | 0.4 | -0.1 | -0.1 | 0.4 | -0.4 | -0.0 | -0.4 | -0.1 | -0.2 | -0.0 | 0.1 | 0.3 | -0.1 | -0.9 | 0.6 | 0.1 | 0.1 | 0.3 | -0.1 | 0.1 | 0.3 |
Bone: periosteal estimation | 0.1 | 0.2 | 1.7 | -0.5 | 0.2 | 0.0 | -1.3 | 0.1 | -0.3 | -0.2 | 0.2 | -0.1 | 0.4 | -0.4 | -0.1 | 0.3 | -0.4 | 0.1 | 0.3 | -0.3 | -0.0 | -0.7 | 0.2 | -0.6 | -0.5 | -0.5 | -0.4 | 0.4 | -0.0 | -0.5 | -0.8 | 0.7 | -0.3 | -0.1 | -0.0 | 0.3 | 0.6 | -0.0 |
Delta time in open arm before/after self-admin | 0.1 | 0.1 | 0.5 | -0.2 | -0.3 | 0.4 | -0.7 | -0.2 | -0.1 | -0.0 | 0.2 | -0.2 | 0.2 | -0.3 | -0.1 | 0.4 | -0.3 | -0.2 | 0.3 | -0.4 | -0.4 | -0.5 | 0.4 | -0.4 | -0.1 | -0.4 | -0.1 | 0.3 | -0.3 | -0.0 | -0.6 | 0.5 | -0.3 | -0.2 | -0.3 | 0.1 | 0.3 | -0.3 |
Delay disc. indifference point, 16s delay | 0.1 | 0.1 | 0.2 | -0.0 | -0.1 | -0.3 | 0.2 | 0.0 | 0.3 | 0.4 | -0.2 | 0.2 | -0.2 | 0.2 | 0.2 | -0.4 | 0.2 | 0.1 | -0.3 | 0.2 | 0.3 | 0.3 | -0.2 | 0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.3 | 0.2 | 0.0 | -0.1 | 0.3 | 0.1 | 0.3 | -0.3 | -0.3 | 0.3 |
Bouts of movement, locomotor time 1 | 0.1 | 0.1 | 1.6 | 0.0 | -0.7 | -0.1 | -0.6 | -0.7 | 0.0 | 0.3 | 0.0 | -0.2 | 0.2 | -0.2 | 0.0 | -0.0 | -0.2 | -0.1 | -0.0 | -0.3 | -0.0 | 0.0 | 0.3 | -0.6 | -0.1 | -0.4 | -0.1 | 0.2 | 0.0 | -0.1 | -1.3 | 0.9 | 0.1 | -0.6 | 0.0 | -0.0 | -0.0 | 0.0 |
Rest time, locomotor task time 1 | 0.1 | 0.1 | 0.8 | 0.1 | -0.9 | 0.1 | 0.3 | -0.6 | -0.1 | -0.0 | 0.2 | -0.3 | 0.2 | -0.2 | -0.2 | 0.1 | -0.2 | -0.2 | 0.1 | -0.2 | -0.1 | 0.0 | 0.3 | -0.3 | -0.1 | -0.2 | -0.1 | 0.2 | -0.1 | -0.1 | -0.2 | 0.3 | -0.1 | -0.5 | -0.1 | 0.1 | -0.0 | -0.1 |
Rest time, locomotor task time 2 | 0.1 | 0.1 | 0.6 | 0.2 | -0.7 | 0.1 | -0.1 | -0.6 | 0.1 | 0.4 | -0.0 | -0.0 | 0.1 | -0.1 | 0.2 | -0.0 | -0.1 | -0.1 | -0.2 | -0.2 | 0.1 | 0.3 | 0.2 | -0.5 | 0.1 | -0.3 | 0.1 | 0.1 | 0.1 | 0.1 | -0.8 | 0.6 | 0.0 | -0.4 | 0.1 | -0.1 | -0.3 | 0.1 |
Distance moved, locomotor task time 2 | 0.1 | 0.1 | 0.8 | -0.3 | 0.3 | 0.1 | 0.4 | 0.3 | -0.3 | -0.5 | 0.2 | -0.2 | 0.1 | -0.1 | -0.4 | 0.1 | -0.1 | -0.3 | 0.3 | 0.0 | -0.3 | -0.0 | 0.0 | 0.3 | -0.3 | 0.1 | -0.3 | 0.0 | -0.3 | -0.3 | 0.9 | -0.6 | -0.1 | 0.2 | -0.3 | 0.3 | 0.0 | -0.3 |
Progressive ratio | 0.1 | 0.2 | 0.5 | -0.4 | -0.5 | 0.2 | -0.7 | -0.3 | -0.4 | -0.3 | 0.4 | -0.5 | 0.4 | -0.4 | -0.3 | 0.4 | -0.4 | -0.4 | 0.2 | -0.3 | -0.3 | -0.2 | 0.3 | -0.6 | -0.5 | -0.4 | -0.6 | 0.4 | -0.3 | -0.5 | -0.7 | 0.5 | -0.2 | -0.5 | -0.3 | 0.4 | 0.2 | -0.3 |
Cu content in liver | 0.1 | 0.1 | 0.2 | -0.3 | 0.1 | 0.3 | -0.4 | 0.1 | -0.3 | -0.3 | 0.2 | -0.1 | 0.3 | -0.3 | -0.2 | 0.3 | -0.3 | 0.1 | 0.3 | -0.3 | -0.2 | -0.2 | 0.2 | -0.3 | -0.3 | -0.3 | -0.4 | 0.3 | -0.2 | -0.3 | -0.1 | 0.2 | -0.3 | -0.2 | -0.2 | 0.3 | 0.4 | -0.2 |
Fe content in liver | 0.1 | 0.1 | 0.5 | -0.4 | 0.3 | 0.0 | -0.7 | 0.3 | -0.3 | -0.3 | 0.1 | 0.1 | 0.3 | -0.4 | -0.1 | 0.3 | -0.3 | 0.2 | 0.3 | -0.3 | 0.0 | -0.3 | 0.2 | -0.4 | -0.4 | -0.3 | -0.5 | 0.4 | 0.1 | -0.4 | -0.3 | 0.3 | -0.3 | -0.1 | 0.1 | 0.3 | 0.3 | 0.0 |
Water consumed over 24 hours | 0.0 | 0.0 | 0.2 | -0.2 | -0.1 | 0.0 | -0.2 | -0.1 | -0.0 | 0.1 | 0.1 | -0.1 | 0.1 | -0.2 | 0.1 | 0.0 | -0.1 | -0.0 | 0.0 | -0.2 | -0.1 | -0.0 | 0.2 | -0.4 | -0.2 | -0.2 | -0.2 | 0.2 | -0.1 | -0.2 | -0.3 | 0.3 | -0.0 | -0.2 | -0.1 | 0.0 | -0.0 | -0.0 |
Reaction time mean minus median AUC | 0.0 | 0.1 | 0.3 | 0.3 | -0.2 | 0.2 | 0.5 | -0.1 | 0.2 | 0.2 | 0.0 | -0.0 | -0.2 | 0.2 | 0.2 | -0.2 | 0.2 | 0.0 | -0.3 | 0.2 | -0.1 | 0.3 | -0.1 | 0.2 | 0.3 | 0.2 | 0.4 | -0.2 | -0.2 | 0.3 | 0.2 | -0.2 | 0.4 | 0.1 | -0.2 | -0.2 | -0.3 | -0.1 |
Reaction time premature initiations | 0.0 | 0.0 | 0.1 | 0.1 | -0.0 | -0.2 | 0.0 | 0.1 | 0.1 | 0.1 | -0.2 | 0.2 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 0.1 | 0.3 | -0.1 | 0.2 | 0.1 | 0.1 | 0.1 | -0.1 | 0.2 | 0.2 | -0.2 | 0.0 | 0.1 | 0.1 | 0.2 | -0.2 | -0.2 | 0.1 |
Pavlov. Cond. magazine entry latency | 0.0 | 0.1 | 0.6 | 0.2 | -0.2 | 0.1 | -0.4 | -0.1 | 0.2 | 0.3 | 0.0 | -0.1 | -0.1 | 0.0 | 0.1 | -0.1 | 0.0 | -0.1 | -0.2 | -0.0 | -0.1 | 0.4 | 0.0 | -0.2 | 0.2 | -0.1 | 0.1 | -0.0 | -0.1 | 0.2 | -0.7 | 0.4 | 0.2 | -0.1 | -0.1 | -0.2 | -0.5 | -0.1 |
Stereotopy head waving bouts, day 7 | 0.0 | 0.0 | 0.4 | -0.0 | -0.5 | -0.0 | 0.6 | -0.3 | -0.1 | -0.1 | 0.0 | -0.1 | 0.0 | -0.0 | -0.1 | -0.0 | -0.0 | -0.1 | -0.0 | 0.0 | 0.1 | 0.4 | 0.0 | 0.1 | -0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -0.0 | 0.2 | -0.1 | 0.0 | -0.2 | 0.0 | 0.0 | -0.2 | 0.1 |
Time in novel zone, hab. session 2 | 0.0 | 0.0 | 0.1 | 0.1 | 0.1 | -0.1 | 0.3 | 0.1 | 0.1 | -0.0 | -0.1 | 0.1 | -0.1 | 0.2 | 0.0 | -0.1 | 0.1 | -0.0 | -0.0 | 0.1 | 0.1 | -0.0 | -0.1 | 0.2 | 0.1 | 0.2 | 0.2 | -0.2 | 0.1 | 0.1 | 0.4 | -0.3 | 0.0 | 0.2 | 0.1 | -0.1 | -0.1 | 0.1 |
Pavlov. Cond. change in total contacts | 0.0 | 0.0 | 0.1 | -0.2 | 0.2 | -0.0 | -0.1 | 0.1 | -0.2 | -0.2 | 0.0 | 0.1 | 0.2 | -0.2 | -0.1 | 0.2 | -0.1 | 0.3 | 0.2 | -0.1 | 0.1 | -0.1 | 0.1 | -0.1 | -0.2 | -0.1 | -0.3 | 0.2 | 0.0 | -0.2 | -0.1 | 0.2 | -0.2 | -0.2 | 0.0 | 0.2 | 0.0 | -0.1 |
Pavlov. Cond. magazine entry number | 0.0 | 0.0 | 0.3 | -0.0 | -0.2 | 0.1 | 0.5 | -0.1 | -0.1 | -0.2 | 0.1 | -0.2 | -0.0 | 0.0 | -0.2 | -0.0 | 0.0 | -0.3 | -0.0 | 0.1 | -0.1 | -0.1 | -0.0 | 0.2 | -0.0 | 0.1 | 0.0 | -0.1 | -0.1 | -0.0 | 0.6 | -0.4 | 0.0 | 0.0 | -0.1 | 0.1 | 0.1 | -0.0 |
Bone: endosteal perimeter | 0.0 | 0.0 | 0.3 | -0.1 | 0.3 | -0.2 | -0.6 | 0.3 | 0.1 | 0.2 | -0.1 | 0.2 | 0.0 | -0.0 | 0.3 | -0.2 | -0.0 | 0.3 | -0.0 | 0.0 | 0.2 | -0.1 | -0.1 | -0.2 | -0.1 | -0.1 | -0.1 | 0.1 | 0.2 | -0.1 | -0.3 | 0.2 | 0.1 | 0.1 | 0.2 | -0.0 | -0.1 | 0.2 |
Bone: final force | 0.0 | 0.1 | 0.5 | 0.1 | 0.4 | -0.4 | -0.7 | 0.4 | 0.2 | 0.2 | -0.3 | 0.2 | -0.1 | 0.1 | 0.2 | -0.2 | 0.1 | 0.2 | -0.1 | 0.1 | 0.3 | -0.2 | -0.2 | 0.1 | 0.1 | 0.1 | 0.2 | -0.1 | 0.4 | 0.1 | -0.4 | 0.1 | 0.2 | 0.3 | 0.4 | -0.2 | 0.2 | 0.3 |
Bone: final moment | 0.0 | 0.1 | 0.6 | 0.1 | 0.4 | -0.3 | -0.7 | 0.3 | 0.1 | 0.2 | -0.2 | 0.2 | -0.1 | 0.1 | 0.2 | -0.1 | 0.1 | 0.2 | -0.0 | 0.1 | 0.3 | -0.3 | -0.1 | 0.0 | 0.1 | 0.1 | 0.1 | -0.1 | 0.3 | 0.1 | -0.4 | 0.1 | 0.1 | 0.3 | 0.3 | -0.1 | 0.2 | 0.3 |
Bone: maximum force | 0.0 | 0.1 | 0.2 | 0.1 | 0.4 | -0.5 | -0.5 | 0.4 | 0.2 | 0.2 | -0.3 | 0.3 | -0.1 | 0.1 | 0.2 | -0.3 | 0.2 | 0.3 | -0.1 | 0.2 | 0.3 | -0.2 | -0.2 | 0.1 | 0.1 | 0.2 | 0.1 | -0.1 | 0.4 | 0.1 | -0.2 | -0.0 | 0.2 | 0.3 | 0.4 | -0.2 | 0.1 | 0.4 |
Bone: maximum moment | 0.0 | 0.0 | 0.3 | -0.0 | 0.3 | -0.3 | -0.5 | 0.3 | 0.1 | 0.1 | -0.2 | 0.2 | -0.1 | 0.1 | 0.2 | -0.2 | 0.1 | 0.1 | -0.0 | 0.1 | 0.2 | -0.2 | -0.1 | 0.0 | -0.0 | 0.1 | 0.1 | -0.1 | 0.3 | -0.0 | -0.2 | 0.0 | 0.1 | 0.3 | 0.3 | -0.1 | 0.1 | 0.3 |
Bone: periosteal perimeter | 0.0 | 0.1 | 0.2 | 0.0 | 0.4 | -0.4 | -0.5 | 0.4 | 0.1 | 0.2 | -0.3 | 0.3 | -0.1 | 0.1 | 0.3 | -0.3 | 0.1 | 0.4 | -0.1 | 0.2 | 0.4 | -0.2 | -0.2 | -0.1 | 0.0 | 0.1 | 0.0 | -0.1 | 0.4 | 0.0 | -0.2 | 0.1 | 0.3 | 0.2 | 0.4 | -0.1 | -0.0 | 0.5 |
Diff in mean of infusions in LGA sessions | 0.0 | 0.0 | 0.2 | -0.2 | 0.0 | 0.1 | -0.4 | -0.0 | -0.1 | -0.0 | 0.2 | -0.1 | 0.2 | -0.2 | -0.0 | 0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.0 | -0.0 | 0.2 | -0.4 | -0.2 | -0.3 | -0.3 | 0.2 | -0.2 | -0.2 | -0.3 | 0.3 | -0.1 | -0.1 | -0.2 | 0.2 | 0.2 | -0.1 |
Time in open arm before self-admin | 0.0 | 0.0 | 0.2 | -0.1 | 0.2 | -0.5 | 0.2 | 0.1 | 0.0 | 0.0 | -0.2 | 0.2 | -0.1 | 0.1 | 0.0 | -0.4 | 0.1 | -0.1 | -0.2 | 0.2 | 0.3 | 0.2 | -0.3 | 0.1 | -0.1 | 0.2 | -0.1 | -0.1 | 0.4 | -0.1 | 0.1 | -0.2 | 0.2 | 0.0 | 0.4 | -0.1 | -0.2 | 0.3 |
Area under the delay curve | 0.0 | 0.1 | 0.4 | 0.0 | -0.0 | -0.1 | 0.6 | 0.0 | 0.2 | 0.2 | -0.1 | 0.1 | -0.2 | 0.2 | 0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | -0.0 | -0.1 | 0.2 | 0.2 | 0.2 | 0.1 | -0.2 | 0.1 | 0.2 | 0.7 | -0.4 | 0.2 | 0.2 | 0.1 | -0.2 | 0.0 | 0.1 |
Delay disc. indifference point, 8s delay | 0.0 | 0.0 | 0.3 | -0.1 | -0.4 | 0.3 | 0.2 | -0.4 | -0.1 | -0.1 | 0.2 | -0.2 | 0.1 | -0.1 | -0.2 | 0.2 | -0.1 | -0.5 | 0.1 | -0.1 | -0.1 | -0.3 | 0.2 | -0.0 | -0.0 | -0.1 | -0.1 | 0.0 | -0.3 | -0.0 | 0.2 | -0.1 | -0.1 | -0.1 | -0.3 | 0.1 | 0.3 | -0.2 |
Delay discount exponential model param | 0.0 | 0.0 | 0.2 | 0.2 | 0.3 | -0.1 | -0.3 | 0.2 | -0.0 | -0.0 | -0.1 | 0.1 | -0.0 | 0.0 | 0.0 | -0.0 | 0.0 | 0.4 | -0.1 | 0.1 | 0.0 | 0.2 | -0.1 | 0.1 | 0.0 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | -0.4 | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | -0.2 | 0.1 |
Delay discount hyperbolic model param | 0.0 | 0.0 | 0.2 | 0.1 | 0.2 | -0.0 | -0.3 | 0.1 | -0.1 | -0.1 | -0.0 | 0.1 | 0.1 | -0.1 | -0.1 | 0.1 | -0.1 | 0.3 | 0.0 | -0.0 | -0.1 | 0.2 | -0.0 | 0.0 | -0.1 | -0.0 | 0.0 | 0.1 | 0.0 | -0.1 | -0.4 | 0.2 | -0.0 | -0.0 | 0.0 | 0.1 | -0.2 | -0.0 |
Seeking ratio, delayed vs. immediate footshock | 0.0 | 0.0 | 0.1 | -0.0 | -0.1 | -0.3 | 0.0 | 0.1 | 0.1 | 0.2 | -0.2 | 0.0 | -0.1 | 0.1 | 0.2 | -0.2 | 0.1 | 0.4 | -0.2 | 0.1 | 0.2 | 0.0 | -0.1 | -0.1 | -0.0 | 0.0 | 0.0 | -0.0 | 0.3 | -0.0 | -0.1 | 0.0 | 0.2 | 0.0 | 0.3 | -0.1 | -0.1 | 0.3 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.