Hub : Genes

Hadha

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024629 0.13 0.1 5.1e-13 0.1 0.1 0.08 0.1 2.3e-11 1.0e-11 7.7e-09 8.1e-11
2 Adipose isoform ratio ENSRNOT00000038649 0.02 0.02 7.5e-03 0.01 0.01 0.01 0.01 7.1e-03 1.1e-02 8.6e-03 9.5e-03
3 Adipose isoform ratio ENSRNOT00000102817 0.02 0.02 8.1e-03 0.01 0.01 0.01 0.01 8.2e-03 1.2e-02 1.0e-02 1.1e-02
4 Brain gene expression ENSRNOG00000024629 0.06 0.05 3.3e-05 0.04 0.04 0.04 0.04 1.1e-04 9.9e-05 1.7e-04 2.1e-04
5 Brain mRNA stability ENSRNOG00000024629 0.07 0.06 6.7e-07 0.07 0.06 0.05 0.06 6.0e-07 1.2e-06 2.4e-05 1.6e-06
6 Liver gene expression ENSRNOG00000024629 0.1 0.08 4.0e-09 0.06 0.07 0.07 0.07 1.9e-07 3.8e-08 5.9e-08 4.7e-08
7 Liver isoform ratio ENSRNOT00000038649 0.09 0.12 7.3e-06 0.04 0.04 0.03 0.04 5.1e-05 2.9e-05 1.0e-04 7.8e-05
8 Liver isoform ratio ENSRNOT00000102817 0.11 0.16 3.3e-06 0.04 0.04 0.04 0.04 2.7e-05 2.1e-05 8.4e-05 6.9e-05
9 Liver mRNA stability ENSRNOG00000024629 0.05 0.06 2.8e-04 0.02 0.04 0.03 0.02 1.8e-03 4.5e-05 1.2e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail2.37.59.42.92.7-3.12.9-2.82.92.9-2.90.6
BMI without tail0.51.11.61.00.7-1.01.0-1.11.01.1-1.11.3
Body weight1.87.89.62.93.1-3.13.0-2.83.02.9-2.9-0.5
Epididymis fat weight14.734.439.26.25.8-6.16.2-6.36.26.3-6.32.6
Glucose0.20.40.50.60.4-0.60.6-0.60.60.6-0.60.7
Heart weight4.15.87.02.62.4-2.42.6-2.62.52.6-2.6-0.8
Left kidney weight0.61.73.4-1.2-0.91.3-1.21.3-1.2-1.21.2-1.8
Right kidney weight0.41.17.80.50.7-0.20.5-0.40.50.5-0.5-2.8
Tail length0.10.40.4-0.7-0.60.7-0.70.5-0.7-0.70.70.4
Length with tail0.20.73.80.51.0-0.50.5-0.50.50.4-0.4-1.9
Length without tail0.51.28.50.41.0-0.50.4-0.20.40.3-0.3-2.9
Liver weight, left0.91.51.91.31.2-1.21.3-1.31.31.4-1.4-0.2
Liver weight, right5.28.610.43.03.2-3.13.1-2.93.13.0-3.0-1.6
Parametrial fat weight8.616.919.64.34.1-4.44.3-4.44.44.3-4.31.5
Retroperitoneal fat weight27.390.5103.310.09.7-10.010.0-10.210.010.1-10.13.4
Intraocular pressure4.15.87.62.52.8-2.42.5-2.32.52.5-2.5-1.6
Extensor digitorum longus weight1.87.18.7-2.8-2.62.9-2.82.8-2.9-2.82.8-0.4
Soleus weight2.26.48.2-2.7-2.52.9-2.72.7-2.7-2.72.70.1
Tibialis anterior weight0.62.22.6-1.6-1.21.6-1.61.6-1.6-1.61.60.1
Tibia length0.92.44.81.41.8-1.41.4-1.61.41.3-1.3-2.2
Number of licking bursts1.21.41.71.21.2-1.31.2-1.21.31.2-1.20.2
Food consumed during 24 hour testing period0.10.10.20.30.2-0.40.3-0.20.30.2-0.20.5
Times rat made contact with spout0.60.71.1-0.8-0.80.7-0.80.8-0.8-0.80.81.0
Mean time between licks in bursts1.62.22.71.61.5-1.61.6-1.51.61.6-1.60.7
Mean num. licks in bursts1.41.62.0-1.4-1.31.4-1.41.4-1.4-1.31.30.2
Std. dev. time between licks in bursts0.80.91.31.01.2-1.11.0-0.91.01.0-1.00.3
Water consumed over 24 hours0.00.00.0-0.1-0.10.0-0.10.2-0.1-0.10.10.0
Indifference point 0 sec0.61.01.60.91.3-1.20.9-0.91.00.8-0.8-1.1
Indifference point AUC0.30.32.7-0.00.0-0.1-0.00.10.0-0.00.11.7
Indifference point function ln k1.62.32.5-1.5-1.61.5-1.51.6-1.5-1.51.5-1.5
Indifference point function log k1.62.32.5-1.5-1.61.5-1.51.6-1.5-1.51.5-1.5
Delay discounting total patch changes 0 sec0.61.01.70.91.3-1.20.9-0.81.00.8-0.8-1.3
Delay discounting total patch changes 12 sec0.91.22.01.11.3-1.41.1-1.01.21.0-1.0-0.3
Delay discounting total patch changes 18 sec0.81.11.51.11.2-1.21.1-1.01.11.0-1.0-0.3
Delay discounting total patch changes 24 sec1.11.31.71.21.3-1.31.2-1.11.21.2-1.2-0.3
Delay discounting total patch changes 6 sec1.82.73.81.71.8-2.01.7-1.61.71.6-1.61.1
Delay discounting time to switch 0 sec0.20.40.50.60.4-0.60.6-0.70.60.7-0.70.1
Delay discounting water rate 0 sec1.01.62.1-1.3-0.81.3-1.31.4-1.3-1.41.4-0.6
Delay discounting water rate 12 sec0.20.31.50.30.3-0.20.3-0.40.30.3-0.3-1.2
Delay discounting water rate 18 sec1.11.52.2-1.2-1.11.1-1.21.2-1.2-1.31.3-1.5
Delay discounting water rate 24 sec0.30.32.30.30.4-0.30.3-0.20.30.3-0.3-1.5
Delay discounting water rate 6 sec0.10.10.2-0.4-0.20.3-0.40.5-0.4-0.40.4-0.4
Locomotor activity0.81.34.80.91.0-0.90.9-0.90.90.9-0.9-2.2
Locomotor testing distance0.40.71.60.70.7-0.60.7-0.80.70.8-0.8-1.2
Locomotor testing rearing0.60.93.8-0.8-0.50.7-0.80.8-0.8-0.80.8-2.0
Light reinforcement 10.50.81.1-0.9-0.40.8-0.91.0-0.9-1.01.0-1.1
Light reinforcement 21.11.42.0-1.2-1.01.0-1.21.4-1.2-1.31.30.7
Reaction time number correct0.10.20.4-0.4-0.50.6-0.40.3-0.4-0.40.40.2
Reaction time mean minus median0.50.75.70.1-0.5-0.10.0-0.20.00.1-0.12.4
Reaction time mean minus median AUC0.30.42.40.3-0.2-0.20.3-0.50.30.3-0.31.5
Reaction time num false alarms1.82.44.11.52.0-1.71.5-1.61.61.4-1.4-1.1
Reaction time num false alarms AUC1.72.44.21.52.0-1.71.5-1.61.61.4-1.4-0.6
Reaction time trials correct on left0.10.20.4-0.4-0.50.6-0.40.3-0.4-0.40.40.2
Reaction time trials on left0.10.20.4-0.4-0.50.6-0.40.3-0.4-0.40.30.2
Reaction time mean0.30.32.80.2-0.2-0.20.2-0.30.20.2-0.21.7
Reaction time mean AUC0.20.22.00.0-0.3-0.10.0-0.10.00.1-0.11.4
Median of all reaction times0.10.11.20.0-0.2-0.10.0-0.10.00.0-0.01.1
Reaction time omissions0.20.30.60.50.4-0.30.5-0.70.50.6-0.6-0.4
Reaction time false alarm rate2.13.04.81.72.2-2.01.7-1.81.81.6-1.6-0.4
Reaction time premature initiation rate0.10.20.20.40.5-0.50.4-0.40.40.4-0.40.2
Reaction time premature initiations0.00.00.00.20.2-0.10.2-0.10.10.2-0.20.1
Std. dev. reaction times0.50.74.40.5-0.1-0.40.5-0.70.50.6-0.62.1
Reaction time trials completed0.10.20.4-0.4-0.50.6-0.40.3-0.4-0.40.30.2
Reaction time trials AUC0.20.20.4-0.5-0.60.7-0.50.3-0.5-0.40.40.3
Social response proportion0.20.20.9-0.4-0.50.6-0.40.3-0.4-0.30.3-0.9
Social responses0.10.20.30.40.5-0.30.4-0.40.40.4-0.4-0.5
Social time0.10.20.7-0.3-0.40.5-0.30.3-0.3-0.30.3-0.8
Conditioned locomotion3.44.05.2-2.1-2.32.1-2.12.1-2.1-2.02.00.9
Cocaine response after cond. corrected0.20.20.3-0.4-0.40.5-0.40.5-0.4-0.40.4-0.1
Cocaine response after cond. not corrected0.70.80.9-0.9-0.91.0-0.90.9-0.9-0.90.90.6
Cocaine response before conditioning2.02.42.7-1.6-1.61.6-1.61.5-1.6-1.61.61.1
Saline control response1.52.02.9-1.4-0.91.4-1.41.5-1.4-1.41.4-1.7
Condit. Reinf. active minus inactive responses1.21.51.7-1.2-1.11.2-1.21.2-1.2-1.21.21.3
Condit. Reinf. active-inactive response ratio0.60.70.8-0.8-0.70.9-0.80.9-0.8-0.80.80.6
Condit. Reinf. active responses0.81.12.8-1.0-0.90.9-1.00.9-1.0-1.01.01.7
Condit. Reinf. inactive responses0.20.31.4-0.4-0.40.3-0.40.4-0.4-0.40.41.2
Condit. Reinf. lever presses1.01.41.8-1.2-1.21.1-1.21.1-1.2-1.11.11.3
Condit. Reinf. lever reinforcers received0.71.03.2-0.9-0.80.8-0.90.9-0.9-0.90.91.8
Pavlov. Cond. lever latency0.91.22.11.01.2-1.01.0-1.01.01.0-1.0-1.4
Pavlov. Cond. magazine entry latency0.20.21.70.1-0.1-0.10.1-0.10.10.1-0.11.3
Pavlov. Cond. change in total contacts0.30.43.1-0.1-0.40.1-0.10.2-0.2-0.10.11.8
Pavlov. Cond. index score0.50.72.9-0.6-0.80.5-0.60.6-0.6-0.60.61.7
Pavlov. Cond. latency score0.50.62.4-0.6-0.80.5-0.60.7-0.6-0.60.61.6
Pavlov. Cond. lever contacts0.30.51.7-0.5-0.70.5-0.50.5-0.5-0.50.51.3
Pavlov. Cond. magazine entry number0.30.32.0-0.3-0.10.4-0.30.3-0.3-0.40.4-1.4
Pavlov. Cond. intertrial magazine entries2.33.03.91.82.0-1.81.8-1.91.81.8-1.8-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.53.4-0.3-0.50.2-0.30.3-0.3-0.20.21.9
Pavlov. Cond. response bias0.60.83.6-0.7-0.90.7-0.70.7-0.7-0.60.61.9
Conditioned reinforcement - actives3.83.86.1-2.0-2.52.2-2.01.8-2.0-1.91.9-0.6
Conditioned reinforcement - inactives5.25.97.0-2.5-2.62.4-2.52.6-2.5-2.52.5-1.4
Conditioned locomotion3.34.05.2-2.1-2.32.1-2.12.1-2.1-2.12.1-0.2
Intermittent access intake day 1-15 change1.91.92.1-1.4-1.31.4-1.41.3-1.4-1.41.4-1.5
Intermittent access intake escalation1.31.23.1-1.0-1.01.0-1.01.0-1.0-1.01.0-1.8
Intermittent access intake escalation 20.50.53.90.20.3-0.10.2-0.20.20.2-0.2-2.0
Intermitt. access day 1 inactive lever presses0.00.10.2-0.2-0.20.1-0.20.5-0.2-0.20.20.0
Intermitt. access day 15 inactive lever presses1.71.82.3-1.3-1.51.1-1.31.3-1.3-1.41.41.5
Intermitt. access escalation Index2.62.32.81.61.7-1.61.6-1.61.61.6-1.6-0.5
Intermittent access day 1 total infusions3.54.05.5-2.1-2.32.1-2.12.0-2.1-2.02.00.8
Intermittent access day 15 total infusions4.14.65.5-2.2-2.42.2-2.22.2-2.2-2.22.2-1.2
Intermittent access terminal intake (last 3 days)3.43.75.1-2.0-2.32.0-2.02.0-2.0-2.02.0-0.0
Intermittent access total infusions4.85.37.1-2.4-2.72.4-2.42.4-2.4-2.42.4-0.4
Intermittent access day 1 locomotion2.32.32.8-1.6-1.61.6-1.61.7-1.6-1.61.6-0.5
Intermittent access day 15 total locomotion0.50.51.3-0.7-1.10.8-0.70.6-0.7-0.60.6-0.1
Intermittent access total locomotion1.01.11.6-1.0-1.31.1-1.01.0-1.1-1.01.0-0.9
Intermittent access standard deviation1.21.35.5-0.9-0.71.0-0.90.8-0.9-0.90.8-2.3
Cocaine induced anxiety0.10.10.3-0.2-0.10.1-0.20.2-0.2-0.20.20.5
Post-drug Anxiety1.31.41.91.21.4-1.31.2-1.21.31.2-1.2-0.1
Baseline Anxiety1.31.41.81.21.1-1.31.2-1.21.21.2-1.20.7
Lifetime Intake5.56.28.3-2.6-2.92.6-2.62.5-2.6-2.62.6-0.5
Incentive Sensitization - Responses1.81.83.9-1.3-1.01.0-1.31.4-1.2-1.41.4-2.0
Incentive Sensitization - Breakpoint1.21.23.3-1.0-0.70.7-1.01.1-1.0-1.11.2-1.8
Progressive ratio test 1 active lever presses2.93.04.4-1.8-2.11.8-1.81.7-1.8-1.81.8-0.0
Progressive ratio test 1 breakpoint2.22.23.4-1.6-1.81.6-1.61.5-1.6-1.61.50.1
Progressive ratio test 1 inactive lever presses5.05.47.6-2.4-2.82.4-2.42.4-2.4-2.42.40.3
Progressive ratio test 2 active lever presses2.32.52.8-1.6-1.71.5-1.61.6-1.6-1.61.6-1.4
Progressive ratio test 2 breakpoint2.42.63.0-1.7-1.71.5-1.71.7-1.6-1.71.7-1.1
Progressive ratio test 2 inactive lever presses2.93.34.2-1.9-2.01.8-1.91.9-1.9-2.02.0-0.4
Total sessions with >9 infusions6.67.28.6-2.8-2.92.9-2.82.7-2.8-2.82.8-1.6
Short access day 1 total inactive lever presses2.73.04.9-1.7-2.22.1-1.71.5-1.8-1.61.6-1.0
Short access day 10 total inactive lever presses0.10.10.20.30.4-0.20.3-0.20.20.3-0.30.5
Short access day 1 total infusions4.64.97.0-2.3-2.62.4-2.32.2-2.3-2.32.3-0.3
Short access day 10 total infusions6.16.78.8-2.7-3.02.8-2.72.7-2.8-2.72.7-0.1
Short access total infusions5.05.57.7-2.4-2.82.6-2.52.3-2.5-2.42.4-0.4
Short access day 1 locomotion5.55.88.4-2.5-2.92.5-2.52.3-2.5-2.52.41.4
Short access day 10 total locomotion1.31.41.8-1.3-1.21.2-1.31.3-1.2-1.31.30.4
Short access total locomotion2.32.33.1-1.6-1.81.6-1.61.6-1.6-1.61.60.3
Compulsive drug intake3.73.64.21.92.0-1.71.9-2.01.92.0-2.0-1.6
One hour access (0.3 mA shock)2.63.05.3-1.6-1.71.9-1.61.5-1.7-1.51.5-2.3
One hour access (shock baseline)5.86.78.3-2.7-2.92.7-2.72.8-2.7-2.72.7-0.7
Number of responses in last shaping day2.42.53.1-1.7-1.71.5-1.71.7-1.6-1.71.80.2
Context. condit. distance diff. score0.20.20.3-0.5-0.40.5-0.50.4-0.5-0.50.5-0.5
Locomotion velocity, session 10.80.81.20.91.1-0.80.9-0.70.90.9-0.9-1.1
Locomotion distance, session 10.50.63.0-0.6-0.10.6-0.60.6-0.6-0.60.6-1.7
Locomotion velocity, session 20.20.21.50.20.4-0.10.2-0.20.20.1-0.1-1.2
Locomotion distance, session 20.30.52.80.30.8-0.30.3-0.30.30.3-0.3-1.7
Locomotion velocity, session 30.10.10.6-0.2-0.10.2-0.20.2-0.2-0.20.20.8
Locomotion distance, session 30.10.10.20.20.4-0.20.2-0.10.20.2-0.2-0.5
Stereotopy head waving bouts, day 32.02.42.7-1.6-1.61.5-1.61.5-1.6-1.61.61.3
Stereotopy head waving duration, day 30.60.70.9-0.8-0.90.8-0.90.7-0.8-0.90.90.8
Locomotion velocity, session 70.10.21.30.10.0-0.20.1-0.10.10.1-0.11.1
Locomotion distance, session 70.91.11.21.11.1-1.11.1-1.01.11.1-1.1-0.8
Stereotopy head waving bouts, day 70.10.11.2-0.00.0-0.0-0.00.1-0.0-0.10.11.1
Stereotopy head waving duration, day 70.60.72.1-0.7-0.70.7-0.70.7-0.7-0.70.71.4
Locomotion velocity, session 80.50.60.8-0.8-0.80.9-0.80.7-0.8-0.80.8-0.3
Locomotion distance, session 80.30.40.8-0.6-0.40.7-0.60.6-0.6-0.60.6-0.9
Degree of sensitization distance0.70.70.90.90.7-1.00.9-0.90.90.9-0.9-0.2
Degree of sensitization stereotypy0.30.30.50.50.6-0.50.5-0.50.50.5-0.50.7
Condit. Reinf. active minus inactive responses1.92.12.91.51.4-1.41.5-1.71.51.5-1.6-0.5
Condit. Reinf. active-inactive response ratio1.51.62.51.41.1-1.31.4-1.61.41.4-1.40.0
Condit. Reinf. active responses0.20.20.50.40.3-0.30.4-0.60.40.5-0.5-0.7
Condit. Reinf. inactive responses0.91.11.3-1.1-0.81.1-1.11.1-1.1-1.11.1-0.9
Incentive salience index mean0.30.30.90.50.5-0.40.5-0.60.50.5-0.5-0.9
Condit. Reinf. lever presses0.60.81.8-0.8-0.70.9-0.80.9-0.8-0.90.9-1.3
Time in familiar zone, hab. session 10.90.81.60.90.9-0.80.9-0.90.90.8-0.8-1.3
Time in novel zone, hab. session 10.30.30.70.50.4-0.50.5-0.50.50.5-0.50.9
Total zone transitions, hab. session 10.20.31.3-0.4-0.30.5-0.40.3-0.4-0.40.4-1.1
Total locomotion distance, hab. session 10.60.81.1-1.0-1.01.1-1.00.9-1.0-1.01.00.1
Locomotion velocity, hab. session 11.21.72.1-1.4-1.51.5-1.41.2-1.4-1.31.30.5
Time in familiar zone, hab. session 20.20.30.40.50.5-0.60.5-0.50.60.5-0.50.1
Time in novel zone, hab. session 20.00.00.00.10.1-0.00.1-0.10.10.1-0.1-0.2
Total zone transitions, hab. session 20.40.62.40.50.9-0.40.5-0.60.60.5-0.5-1.5
Total locomotion distance, hab. session 20.20.30.40.60.6-0.50.6-0.60.60.6-0.60.5
Locomotion velocity, hab. session 20.10.20.20.40.4-0.40.4-0.40.40.4-0.40.4
Novel to familiar place preference ratio0.40.40.80.70.9-0.70.7-0.60.70.7-0.70.1
Novelty place preference0.70.71.20.91.1-0.90.9-0.80.90.9-0.90.1
Time in novel zone, NPP test0.60.71.10.91.1-0.90.9-0.70.90.8-0.80.0
Total zone transitions, NPP test0.81.12.5-1.0-0.61.1-1.01.0-1.0-1.01.0-1.6
Total locomotion distance, NPP test1.01.41.7-1.3-1.01.3-1.31.3-1.3-1.31.3-0.7
Locomotion velocity, NPP test1.31.92.4-1.5-1.21.5-1.51.5-1.5-1.51.5-0.5
Pavlov. Cond. lever latency0.50.71.90.70.6-0.80.7-0.80.70.7-0.71.4
Pavlov. Cond. magazine entry latency0.20.31.90.20.3-0.20.3-0.20.30.2-0.2-1.4
Pavlov. Cond. change in total contacts0.30.43.0-0.20.00.2-0.20.2-0.2-0.20.2-1.7
Pavlov. Cond. index score0.30.43.3-0.2-0.00.3-0.20.3-0.2-0.20.2-1.8
Pavlov. Cond. latency score0.30.43.7-0.10.20.1-0.00.1-0.0-0.10.1-1.9
Pavlov. Cond. lever contacts0.50.61.8-0.7-0.50.7-0.70.7-0.6-0.70.7-1.3
Pavlov. Cond. magazine entry number0.10.11.1-0.0-0.1-0.0-0.0-0.0-0.0-0.00.01.0
Pavlov. Cond. intertrial magazine entries2.02.33.0-1.6-1.71.6-1.61.5-1.6-1.61.60.6
Pavlov. Cond. lever-magazine prob. diff.0.50.72.7-0.6-0.50.7-0.60.7-0.6-0.70.7-1.6
Pavlov. Cond. response bias0.91.11.5-1.0-1.01.1-1.01.1-1.0-1.01.0-1.2
Bone: apparent density2.64.35.1-2.2-2.22.2-2.22.3-2.2-2.22.2-0.3
Bone surface0.50.81.1-1.0-0.80.9-1.01.0-0.9-1.01.0-0.5
Bone volume1.32.32.8-1.6-1.51.5-1.61.7-1.6-1.61.6-0.4
Bone: connectivity density1.72.73.1-1.7-1.61.8-1.71.7-1.7-1.71.7-1.1
Bone: cortical apparent density0.00.00.1-0.1-0.30.2-0.10.0-0.1-0.00.00.2
Bone: cortical area0.10.20.70.30.7-0.30.3-0.20.30.2-0.2-0.8
Bone: cortical porosity3.23.54.3-2.0-1.71.9-2.02.1-2.0-2.02.01.2
Bone: cortical porosity2.52.73.3-1.7-1.61.7-1.71.8-1.7-1.71.71.1
Bone: cortical thickness0.30.40.80.70.9-0.70.7-0.70.70.7-0.70.1
Bone: cortical thickness0.40.40.5-0.7-0.60.6-0.70.7-0.7-0.70.70.5
Bone: cortical tissue density0.00.00.1-0.0-0.20.1-0.0-0.1-0.00.0-0.00.2
Bone: elastic displacement1.61.82.4-1.3-1.61.3-1.31.2-1.3-1.31.31.2
Bone: elastic work0.50.72.0-0.7-0.80.6-0.70.6-0.7-0.70.71.4
Bone: endosteal estimation0.20.42.3-0.4-0.20.3-0.40.4-0.3-0.40.4-1.5
Bone: endosteal perimeter0.00.10.5-0.00.2-0.2-0.00.10.0-0.10.1-0.7
Bone: final force0.00.10.30.10.4-0.20.1-0.10.10.1-0.1-0.5
Bone: final moment0.00.10.30.10.3-0.10.1-0.10.10.1-0.1-0.6
Bone: marrow area0.20.42.0-0.4-0.20.3-0.40.5-0.4-0.50.5-1.4
Bone: maximum diameter0.00.10.40.00.3-0.1-0.00.00.0-0.10.1-0.6
Bone: maximum force0.00.10.30.10.4-0.30.1-0.10.20.1-0.1-0.5
Bone: maximum moment0.00.00.30.10.3-0.20.1-0.10.10.1-0.1-0.5
Bone: minimum diameter0.71.33.80.91.4-1.00.9-0.91.00.9-0.8-1.9
Bone: periosteal estimation0.20.42.6-0.4-0.00.3-0.40.4-0.3-0.50.5-1.6
Bone: periosteal perimeter0.00.10.30.10.4-0.30.1-0.10.10.0-0.0-0.6
Bone: post-yield work1.92.62.7-1.6-1.51.6-1.61.5-1.6-1.61.6-1.6
Bone: stiffness0.20.31.00.40.8-0.50.4-0.40.40.4-0.4-1.0
Bone: tissue strength0.60.50.80.80.5-0.60.8-0.80.70.8-0.90.7
Bone: trabecular number2.94.55.2-2.2-2.22.1-2.22.3-2.2-2.32.3-0.9
Bone: trabecular spacing0.81.01.41.01.2-1.01.0-1.11.01.0-1.0-0.8
Bone: trabecular thickness0.40.50.8-0.7-0.80.6-0.70.8-0.7-0.70.70.9
Bone: trabecular tissue density0.20.20.5-0.4-0.70.5-0.40.3-0.5-0.30.30.6
Breakpoint value in progressive ratio session0.91.01.4-1.1-1.00.9-1.11.2-1.1-1.11.1-0.7
Distance traveled before self-admin0.20.20.5-0.3-0.70.6-0.30.3-0.4-0.20.20.5
Distance traveled after self-admin0.40.52.60.50.5-0.30.5-0.40.50.5-0.5-1.6
Delta time in closed arm before/after self-admin0.40.40.90.50.9-0.80.5-0.40.60.4-0.4-0.8
Delta time in open arm before/after self-admin0.10.10.3-0.2-0.30.4-0.20.1-0.2-0.10.1-0.5
Diff in mean of infusions in LGA sessions0.00.00.1-0.2-0.20.1-0.20.4-0.2-0.20.20.0
Extinction: sum of active levers before priming1.31.37.5-0.7-0.40.6-0.70.8-0.7-0.80.8-2.7
Active lever presses in extinction session 61.81.72.1-1.3-1.31.2-1.31.5-1.3-1.41.4-1.3
Delta distance traveled before/after self-admin1.61.72.41.31.5-1.51.4-1.31.41.3-1.3-0.3
Delta ambulatory time before/after self-admin0.40.40.80.60.9-0.80.6-0.50.70.6-0.5-0.2
Time in closed arm before self-admin0.10.10.20.40.3-0.30.4-0.30.40.4-0.4-0.4
Time in closed arm after self-admin0.70.71.00.80.7-0.90.9-0.70.80.9-0.9-1.0
Time in open arm before self-admin0.10.11.00.10.4-0.30.1-0.10.10.0-0.01.0
Time in open arm after self-admin0.20.20.4-0.5-0.50.7-0.50.4-0.5-0.50.4-0.3
Sum of active levers in priming session hrs 5-60.20.20.40.30.7-0.60.3-0.10.40.3-0.2-0.3
Time to tail flick, vehicle, before self-admin0.50.50.90.70.6-0.90.7-0.60.70.6-0.60.7
Time to tail flick, vehicle, after self-admin5.86.27.92.61.8-2.32.6-2.72.52.8-2.82.1
Time to tail flick, test, before self-admin1.21.21.7-1.1-1.30.8-1.11.2-1.0-1.11.10.9
Time to tail flick, test, after self-admin0.90.91.3-1.0-0.90.9-1.01.1-1.0-1.11.1-0.4
Delta time to tail flick, vehicle, before/after SA2.22.22.81.51.1-1.21.5-1.61.41.6-1.71.6
Delta time to tail flick, test, before/after SA1.61.51.7-1.2-1.11.3-1.21.2-1.2-1.31.3-1.1
Ambulatory time before self-admin0.10.10.4-0.3-0.60.6-0.30.2-0.3-0.20.1-0.0
Ambulatory time after self-admin0.20.21.30.30.3-0.20.3-0.20.30.3-0.3-1.1
Total heroin consumption1.31.61.9-1.3-1.31.1-1.31.4-1.3-1.31.3-0.9
Area under the delay curve0.10.10.50.20.1-0.20.2-0.10.20.3-0.30.7
Delay disc. indifference point, 0s delay1.11.21.51.11.2-1.21.1-1.01.11.1-1.1-0.1
Delay disc. indifference point, 16s delay0.20.21.00.30.3-0.40.3-0.20.30.3-0.31.0
Delay disc. indifference point, 2s delay0.10.20.30.30.5-0.40.4-0.30.30.4-0.40.5
Delay disc. indifference point, 24s delay2.32.22.8-1.6-1.51.6-1.61.7-1.6-1.61.6-0.2
Delay disc. indifference point, 4s delay0.20.20.30.50.4-0.50.5-0.40.50.6-0.60.3
Delay disc. indifference point, 8s delay0.10.10.6-0.1-0.30.2-0.10.1-0.1-0.00.00.8
Delay discount exponential model param0.10.10.50.00.1-0.0-0.0-0.10.0-0.00.1-0.7
Delay discount hyperbolic model param0.10.10.7-0.10.00.1-0.10.0-0.0-0.10.1-0.8
Fecal boli incidents, locomotor time 13.13.44.8-1.8-1.61.8-1.81.9-1.8-1.91.9-2.2
Change in fecal boli incidents, locomotor task3.02.93.51.81.8-1.91.8-1.81.81.8-1.8-0.1
Time >=10cm from walls, locomotor time 10.40.40.5-0.7-0.70.6-0.70.7-0.6-0.70.7-0.2
Bouts of movement, locomotor time 10.20.32.3-0.00.0-0.0-0.00.0-0.0-0.00.01.5
Total resting periods, locomotor time 10.30.33.0-0.1-0.00.0-0.10.1-0.1-0.10.11.7
Rest time, locomotor task time 10.20.21.5-0.1-0.10.1-0.10.1-0.1-0.10.11.2
Distance moved, locomotor task time 10.20.20.50.40.4-0.40.4-0.40.40.4-0.4-0.7
Vertical activity count, locomotor time 10.20.20.30.50.4-0.50.5-0.50.50.5-0.50.0
Time >=10cm from walls, locomotor time 21.51.62.0-1.3-1.31.2-1.31.4-1.4-1.31.30.1
Bouts of movement, locomotor time 20.60.60.80.80.8-0.90.8-0.80.80.8-0.80.5
Total resting periods, locomotor time 20.70.80.90.90.9-1.00.9-0.80.90.8-0.81.0
Rest time, locomotor task time 20.20.32.30.10.10.00.1-0.10.10.1-0.11.5
Distance moved, locomotor task time 20.10.10.2-0.2-0.30.1-0.20.2-0.2-0.20.2-0.5
Vertical activity count, locomotor time 20.30.30.4-0.6-0.60.5-0.60.7-0.6-0.60.6-0.2
Weight adjusted by age0.80.95.20.60.7-0.70.6-0.40.60.5-0.52.3
Seeking ratio, delayed vs. immediate footshock0.00.00.10.10.3-0.20.10.10.10.0-0.00.2
Locomotion in novel chamber0.40.40.60.70.5-0.80.7-0.60.70.7-0.7-0.2
Locomotion in novel chamber post-restriction2.73.24.81.92.2-2.11.9-1.61.91.8-1.8-0.5
Progressive ratio0.30.41.5-0.5-0.30.3-0.50.7-0.4-0.50.51.2
Food seeking constrained by brief footshock14.117.221.1-4.4-3.64.2-4.44.6-4.3-4.54.5-2.3
Seeking ratio, punishment vs. effort1.72.14.9-1.4-1.21.4-1.41.3-1.4-1.31.3-2.2
Run reversals in cocaine runway, females0.40.40.8-0.6-0.80.6-0.60.6-0.6-0.50.50.9
Run reversals in cocaine runway, males1.11.11.4-1.1-1.11.2-1.11.2-1.1-1.01.0-0.4
Latency to leave start box in cocaine runway0.70.83.4-0.7-1.00.6-0.70.6-0.7-0.60.61.8
Latency to leave start box in cocaine runway, F0.30.31.9-0.3-0.60.3-0.30.1-0.3-0.30.31.4
Latency to leave start box in cocaine runway, M1.81.72.6-1.3-1.61.3-1.31.4-1.4-1.31.20.7
Cd content in liver0.50.51.60.60.7-0.60.6-0.70.60.6-0.6-1.3
Co content in liver4.65.46.3-2.4-2.52.4-2.42.2-2.4-2.42.41.5
Cu content in liver0.40.43.3-0.3-0.20.3-0.30.3-0.3-0.30.3-1.8
Fe content in liver0.60.75.0-0.40.10.3-0.40.4-0.3-0.40.4-2.2
K content in liver1.71.72.41.31.6-1.41.3-1.31.41.3-1.3-0.9
Mg content in liver1.92.03.21.31.7-1.51.3-1.21.41.2-1.2-1.8
Mn content in liver0.30.40.90.50.7-0.70.5-0.30.50.5-0.50.9
Na content in liver1.81.92.5-1.4-1.11.3-1.41.6-1.4-1.51.5-1.1
Rb content in liver0.70.93.50.70.9-0.80.7-0.70.80.7-0.6-1.9
Se content in liver1.01.32.71.01.3-1.11.0-0.91.11.0-0.9-1.6
Sr content in liver0.20.11.00.2-0.0-0.20.2-0.20.20.2-0.21.0
Zn content in liver1.51.62.31.31.5-1.41.3-1.21.31.2-1.2-1.1