Hub : Genes

Proser3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024625 0.06 0.04 1.1e-05 0.03 0.03 0.03 0.03 1.6e-04 5.4e-04 8.0e-04 8.1e-04
2 BLA gene expression ENSRNOG00000024625 0.3 0.11 2.9e-09 0.13 0.16 0.17 0.17 2.9e-07 6.3e-09 2.9e-09 1.2e-09
3 Brain gene expression ENSRNOG00000024625 0.33 0.11 0.0e+00 0.39 0.36 0.37 0.39 1.6e-38 1.1e-34 6.9e-36 1.3e-38
4 IL gene expression ENSRNOG00000024625 0.64 0.15 8.4e-08 0.11 0.22 0.21 0.2 1.6e-03 5.0e-06 8.0e-06 1.7e-05
5 LHb gene expression ENSRNOG00000024625 0.27 0.15 2.7e-05 0.13 0.16 0.2 0.14 5.5e-04 1.3e-04 2.2e-05 2.8e-04
6 Liver gene expression ENSRNOG00000024625 0.15 0.07 0.0e+00 0.13 0.13 0.12 0.13 1.3e-14 7.9e-14 1.2e-13 7.0e-14
7 NAcc gene expression ENSRNOG00000024625 0.12 0.07 8.8e-06 0.08 0.08 0.06 0.07 2.3e-06 2.7e-06 2.8e-05 3.2e-06
8 OFC gene expression ENSRNOG00000024625 0.29 0.16 2.0e-04 0.12 0.13 0.12 0.11 7.1e-04 5.0e-04 1.1e-03 1.6e-03
9 PL gene expression ENSRNOG00000024625 0.44 0.16 2.2e-16 0.2 0.22 0.22 0.21 2.5e-15 1.4e-16 1.1e-16 3.3e-16
10 PL intron excision ratio chr1:85800656:85800737 0.04 0.03 6.0e-04 0.04 0.02 0.01 0.02 5.4e-04 1.7e-02 2.7e-02 1.1e-02
11 PL intron excision ratio chr1:85800659:85800737 0.04 0.03 7.5e-04 0.04 0.02 0.01 0.02 4.7e-04 1.8e-02 2.6e-02 1.1e-02
12 PL mRNA stability ENSRNOG00000024625 0.04 0.03 6.1e-04 0.03 0.03 0.02 0.03 1.7e-03 1.8e-03 7.6e-03 3.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.20.60.8-0.8-0.7-0.9-0.4-0.8-0.7-0.9-0.8-0.60.9-0.90.6
BMI without tail0.00.10.20.30.40.40.00.20.10.20.20.2-0.40.40.3
Body weight2.18.814.23.02.23.01.33.43.82.93.30.6-3.43.4-3.7
Epididymis fat weight0.10.20.60.20.00.2-0.30.50.70.20.3-0.4-0.60.6-0.7
Glucose0.30.51.40.81.00.81.1-0.3-0.10.80.41.20.2-0.20.7
Heart weight0.40.51.2-0.8-1.0-0.6-1.00.60.5-0.6-0.3-1.1-0.50.5-0.9
Left kidney weight3.39.513.83.53.03.42.62.93.23.43.71.8-2.62.6-3.6
Right kidney weight4.813.619.54.03.33.92.63.84.03.94.31.8-3.73.7-4.4
Tail length3.711.117.33.42.73.61.53.93.73.43.61.2-4.24.2-3.2
Length with tail5.520.131.84.22.94.31.45.65.64.14.80.7-5.65.6-5.3
Length without tail3.57.716.22.21.32.20.53.73.92.22.9-0.3-3.43.4-4.0
Liver weight, left0.40.71.90.61.00.71.4-0.7-0.60.70.41.30.7-0.70.2
Liver weight, right0.20.41.40.50.90.60.5-0.6-0.70.70.21.20.4-0.4-0.0
Parametrial fat weight2.54.811.32.63.12.63.4-0.3-0.42.72.23.3-0.00.0-0.4
Retroperitoneal fat weight0.62.14.30.61.30.61.8-2.1-1.70.6-0.11.91.8-1.81.6
Intraocular pressure0.20.30.6-0.6-0.7-0.7-0.70.1-0.0-0.7-0.6-0.70.3-0.30.7
Extensor digitorum longus weight0.41.45.21.21.41.12.3-0.7-0.21.01.11.40.6-0.6-1.3
Soleus weight0.10.20.40.30.50.20.7-0.6-0.40.20.10.60.4-0.4-0.0
Tibialis anterior weight0.72.37.01.82.01.72.6-0.20.31.61.71.90.2-0.2-1.2
Tibia length2.26.213.92.01.22.00.83.03.32.02.6-0.3-3.23.2-3.7
Number of licking bursts3.13.75.5-2.2-2.0-2.3-1.6-1.8-1.7-2.2-2.3-1.41.5-1.51.9
Food consumed during 24 hour testing period0.70.82.0-0.4-0.8-0.4-1.41.10.8-0.5-0.3-1.3-1.11.1-0.5
Times rat made contact with spout0.60.72.11.01.21.01.5-0.2-0.20.90.61.20.0-0.00.3
Mean time between licks in bursts0.20.30.8-0.7-0.7-0.7-0.90.0-0.4-0.7-0.6-0.60.2-0.20.1
Mean num. licks in bursts3.34.06.22.52.42.52.21.41.32.42.31.9-1.41.4-1.6
Std. dev. time between licks in bursts1.82.27.1-1.7-1.9-1.7-2.70.2-0.3-1.7-1.6-1.9-0.00.00.7
Water consumed over 24 hours0.50.61.80.70.50.60.20.90.80.50.7-0.1-0.90.9-1.3
Indifference point 0 sec0.10.10.6-0.3-0.3-0.3-0.70.4-0.0-0.2-0.3-0.4-0.10.10.2
Indifference point AUC0.20.30.70.20.40.10.3-0.8-0.7-0.1-0.20.50.6-0.60.9
Indifference point function ln k0.20.31.30.30.20.4-0.10.90.70.40.5-0.1-0.50.5-1.1
Indifference point function log k0.20.31.30.30.20.4-0.10.90.70.40.5-0.1-0.50.5-1.1
Delay discounting total patch changes 0 sec0.10.10.6-0.2-0.3-0.2-0.80.50.2-0.2-0.2-0.4-0.20.2-0.0
Delay discounting total patch changes 12 sec0.10.10.60.20.40.2-0.0-0.3-0.60.1-0.20.60.0-0.00.8
Delay discounting total patch changes 18 sec0.20.20.6-0.5-0.6-0.5-0.7-0.00.1-0.6-0.5-0.70.1-0.10.7
Delay discounting total patch changes 24 sec0.50.61.3-0.0-0.5-0.1-0.81.11.1-0.20.1-1.2-1.11.1-0.6
Delay discounting total patch changes 6 sec0.00.00.30.00.10.0-0.30.1-0.20.1-0.10.20.1-0.10.6
Delay discounting time to switch 0 sec0.50.72.6-0.20.2-0.10.7-1.3-1.20.0-0.31.00.9-0.91.6
Delay discounting water rate 0 sec0.50.81.3-0.9-0.7-1.0-0.9-0.8-1.0-1.0-1.1-0.61.1-1.10.1
Delay discounting water rate 12 sec0.50.71.90.0-0.30.1-1.01.41.30.10.0-0.8-1.11.1-0.4
Delay discounting water rate 18 sec0.10.10.3-0.3-0.2-0.3-0.5-0.3-0.5-0.4-0.6-0.00.3-0.30.5
Delay discounting water rate 24 sec1.72.46.5-1.7-2.0-1.7-2.60.50.3-1.9-1.5-2.40.0-0.0-0.4
Delay discounting water rate 6 sec1.01.42.9-0.5-1.0-0.5-1.71.61.3-0.5-0.2-1.7-1.21.2-1.4
Locomotor activity0.91.44.41.11.71.01.4-0.7-0.81.10.52.10.9-0.91.1
Locomotor testing distance0.50.82.20.71.10.61.0-0.6-0.60.80.21.51.0-1.01.3
Locomotor testing rearing0.81.23.3-0.40.1-0.50.3-1.4-1.2-0.3-0.90.61.8-1.81.7
Light reinforcement 10.30.61.3-1.0-1.0-1.0-1.2-0.4-0.2-0.9-0.9-0.80.3-0.30.4
Light reinforcement 21.52.04.1-1.4-0.9-1.4-0.5-1.9-2.0-1.3-1.5-0.21.8-1.80.5
Reaction time number correct0.10.10.80.20.20.20.30.10.10.30.30.2-0.10.1-0.9
Reaction time mean minus median0.40.60.90.90.60.80.50.80.80.70.90.3-0.90.9-0.3
Reaction time mean minus median AUC1.11.41.91.31.01.30.91.31.31.21.40.5-1.41.4-1.0
Reaction time num false alarms0.50.71.4-0.7-0.6-0.8-0.2-1.2-0.9-0.9-0.9-0.21.1-1.10.9
Reaction time num false alarms AUC0.60.91.7-0.8-0.6-0.8-0.2-1.3-1.1-1.0-1.0-0.11.2-1.21.3
Reaction time trials correct on left0.10.10.80.20.20.20.30.10.10.30.30.2-0.10.1-0.9
Reaction time trials on left0.10.10.80.30.30.30.30.10.10.30.30.3-0.10.1-0.9
Reaction time mean0.20.20.70.50.20.50.20.70.80.30.5-0.1-0.70.7-0.1
Reaction time mean AUC0.10.20.40.50.30.50.20.50.60.30.40.1-0.60.60.1
Median of all reaction times0.10.10.30.1-0.10.2-0.10.40.60.00.1-0.2-0.40.40.1
Reaction time omissions0.20.30.60.60.70.70.70.2-0.00.60.50.80.1-0.10.5
Reaction time false alarm rate0.60.82.1-0.8-0.7-0.8-0.4-1.1-0.9-1.0-1.0-0.31.0-1.01.5
Reaction time premature initiation rate0.70.92.8-1.1-1.2-1.1-1.7-0.0-0.2-1.1-1.1-1.1-0.10.11.0
Reaction time premature initiations0.40.62.1-0.9-1.0-0.9-1.4-0.0-0.1-0.9-0.9-1.0-0.10.10.5
Std. dev. reaction times0.50.71.70.70.30.70.11.21.30.50.8-0.2-1.11.1-0.5
Reaction time trials completed0.10.10.80.30.30.30.30.10.10.30.30.3-0.10.1-0.9
Reaction time trials AUC0.20.20.60.50.60.50.7-0.00.10.50.50.60.1-0.1-0.8
Social response proportion0.80.92.20.40.00.3-0.21.30.90.30.8-0.4-1.51.5-1.5
Social responses0.10.10.40.0-0.1-0.1-0.30.60.1-0.10.2-0.1-0.60.6-0.5
Social time1.41.84.40.2-0.50.2-0.82.01.90.20.8-1.2-1.91.9-2.1
Conditioned locomotion0.80.91.3-1.1-0.9-1.1-0.7-1.1-1.1-1.1-1.1-0.51.0-1.00.6
Cocaine response after cond. corrected0.80.92.61.01.31.01.5-0.3-0.51.10.81.60.3-0.30.3
Cocaine response after cond. not corrected1.71.95.11.61.91.52.0-0.1-0.31.71.22.30.3-0.30.4
Cocaine response before conditioning0.91.12.01.20.91.10.31.41.31.21.00.5-1.21.2-0.4
Saline control response0.20.20.40.50.60.50.60.0-0.00.70.40.70.3-0.30.1
Condit. Reinf. active minus inactive responses0.60.71.60.60.40.7-0.11.21.00.70.8-0.0-1.11.1-1.3
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.00.00.2-0.3-0.10.0-0.00.10.2-0.2-0.2
Condit. Reinf. active responses1.41.94.60.90.30.9-0.52.21.90.91.1-0.5-2.02.0-1.7
Condit. Reinf. inactive responses1.51.95.20.3-0.40.2-1.42.31.90.20.6-1.2-2.02.0-1.3
Condit. Reinf. lever presses4.36.011.62.11.52.20.53.22.92.22.50.3-3.43.4-2.7
Condit. Reinf. lever reinforcers received1.52.15.00.60.00.7-0.92.22.10.71.0-0.9-2.12.1-1.7
Pavlov. Cond. lever latency2.63.57.4-1.2-0.5-1.20.2-2.7-2.5-1.2-1.60.62.7-2.72.5
Pavlov. Cond. magazine entry latency1.21.43.60.70.30.8-0.31.81.40.70.9-0.2-1.91.9-1.2
Pavlov. Cond. change in total contacts3.75.212.01.10.11.2-0.73.53.41.11.8-1.3-3.33.3-2.8
Pavlov. Cond. index score2.63.48.01.10.41.2-0.32.62.41.21.5-0.6-2.82.8-2.2
Pavlov. Cond. latency score2.32.97.21.00.31.0-0.42.52.31.01.3-0.6-2.72.7-2.0
Pavlov. Cond. lever contacts2.43.47.81.00.31.0-0.32.62.51.11.5-0.8-2.82.8-2.4
Pavlov. Cond. magazine entry number2.42.96.4-1.2-0.6-1.3-0.1-2.3-2.3-1.2-1.60.32.5-2.52.1
Pavlov. Cond. intertrial magazine entries0.50.61.5-0.6-0.3-0.60.2-1.1-1.0-0.5-0.60.21.2-1.20.9
Pavlov. Cond. lever-magazine prob. diff.2.73.47.81.30.61.3-0.12.62.41.31.6-0.3-2.82.8-2.2
Pavlov. Cond. response bias2.73.88.80.90.11.0-0.52.82.71.01.5-1.0-3.03.0-2.5
Conditioned reinforcement - actives0.10.10.4-0.3-0.3-0.2-0.4-0.5-0.2-0.2-0.5-0.00.4-0.40.6
Conditioned reinforcement - inactives2.62.97.8-1.9-2.3-1.9-2.80.40.4-2.0-1.4-2.6-0.80.8-0.7
Conditioned locomotion3.03.65.2-2.3-2.0-2.2-1.7-2.0-1.6-2.2-2.3-1.31.7-1.71.3
Intermittent access intake day 1-15 change1.71.73.41.10.61.00.41.71.81.01.4-0.2-1.61.6-1.8
Intermittent access intake escalation1.51.53.30.90.30.80.21.61.80.71.2-0.5-1.61.6-1.7
Intermittent access intake escalation 21.21.22.11.10.81.10.51.41.41.01.20.3-1.41.4-0.9
Intermitt. access day 1 inactive lever presses1.51.65.10.70.30.6-0.21.81.30.61.1-0.3-2.32.3-1.5
Intermitt. access day 15 inactive lever presses0.80.91.9-1.0-1.2-1.0-1.30.40.2-1.0-0.5-1.4-0.90.9-0.6
Intermitt. access escalation Index0.80.71.6-1.2-1.3-1.0-0.9-0.3-0.1-0.9-0.8-1.10.6-0.60.4
Intermittent access day 1 total infusions4.24.77.0-2.6-2.5-2.6-2.4-1.7-1.4-2.6-2.7-2.01.7-1.71.7
Intermittent access day 15 total infusions2.22.45.5-1.9-2.2-1.9-2.3-0.20.1-1.9-1.6-2.30.1-0.10.2
Intermittent access terminal intake (last 3 days)2.72.96.0-2.1-2.3-2.1-2.4-0.6-0.4-2.1-2.0-2.20.5-0.50.8
Intermittent access total infusions3.03.36.1-2.2-2.3-2.2-2.5-0.8-0.5-2.2-2.1-2.20.8-0.81.2
Intermittent access day 1 locomotion4.34.47.4-2.5-2.6-2.6-2.7-1.3-1.1-2.7-2.5-2.41.0-1.01.1
Intermittent access day 15 total locomotion2.22.45.8-1.7-2.1-1.8-2.4-0.10.1-2.0-1.6-2.40.1-0.10.0
Intermittent access total locomotion3.03.35.2-2.1-2.1-2.2-2.2-1.3-1.2-2.3-2.3-1.81.1-1.11.4
Intermittent access standard deviation2.32.46.00.3-0.50.4-1.02.32.30.30.9-1.3-2.52.5-1.5
Cocaine induced anxiety0.50.51.10.60.50.80.60.80.50.70.80.4-0.80.8-1.1
Post-drug Anxiety0.10.10.5-0.10.10.00.5-0.3-0.70.00.00.5-0.00.00.2
Baseline Anxiety1.41.52.4-1.4-1.1-1.4-0.8-1.5-1.4-1.3-1.4-0.51.0-1.01.3
Lifetime Intake1.82.03.0-1.7-1.7-1.7-1.7-0.9-0.6-1.7-1.7-1.50.9-0.91.1
Incentive Sensitization - Responses0.30.30.6-0.6-0.7-0.7-0.7-0.20.0-0.7-0.6-0.80.4-0.40.1
Incentive Sensitization - Breakpoint0.20.20.5-0.5-0.7-0.6-0.6-0.20.1-0.6-0.5-0.70.4-0.40.0
Progressive ratio test 1 active lever presses1.31.33.6-1.1-1.6-1.0-1.90.60.8-1.1-0.8-1.9-0.50.5-0.4
Progressive ratio test 1 breakpoint0.90.92.4-0.7-1.2-0.6-1.50.81.0-0.7-0.4-1.6-0.80.8-0.6
Progressive ratio test 1 inactive lever presses1.92.15.7-1.6-1.9-1.6-2.40.40.3-1.6-1.2-2.2-0.70.7-0.5
Progressive ratio test 2 active lever presses1.01.12.7-1.2-1.5-1.1-1.7-0.00.3-1.2-1.1-1.60.1-0.10.2
Progressive ratio test 2 breakpoint0.80.92.3-1.1-1.4-1.0-1.5-0.10.2-1.1-1.0-1.40.2-0.20.3
Progressive ratio test 2 inactive lever presses3.74.310.6-2.4-2.9-2.5-3.20.40.4-2.5-1.7-3.3-0.60.6-0.7
Total sessions with >9 infusions0.60.71.6-0.6-0.4-0.7-0.4-1.1-0.9-0.6-1.0-0.11.1-1.11.3
Short access day 1 total inactive lever presses2.93.37.3-2.2-2.5-2.2-2.7-0.10.1-2.3-1.7-2.7-0.20.2-0.7
Short access day 10 total inactive lever presses0.70.72.3-0.3-0.6-0.4-0.81.00.8-0.30.3-1.0-1.11.1-1.5
Short access day 1 total infusions0.20.30.4-0.6-0.6-0.7-0.6-0.4-0.1-0.5-0.6-0.60.4-0.4-0.2
Short access day 10 total infusions0.50.50.8-0.9-0.8-0.8-0.6-0.8-0.4-0.7-0.8-0.60.7-0.70.9
Short access total infusions0.50.61.2-0.6-0.5-0.6-0.3-1.0-0.7-0.6-0.9-0.11.1-1.11.0
Short access day 1 locomotion0.20.20.5-0.6-0.5-0.5-0.4-0.7-0.5-0.5-0.5-0.40.3-0.30.2
Short access day 10 total locomotion1.01.13.6-0.9-1.2-0.9-1.90.60.4-1.0-0.8-1.5-0.90.90.1
Short access total locomotion1.11.11.8-1.1-0.9-1.1-1.0-1.2-1.1-1.2-1.3-0.60.8-0.81.1
Compulsive drug intake0.10.00.20.10.10.3-0.10.40.20.20.10.1-0.10.1-0.5
One hour access (0.3 mA shock)1.51.75.7-1.0-1.5-0.9-2.41.01.1-1.1-0.9-2.0-1.01.0-0.3
One hour access (shock baseline)1.11.23.5-1.1-1.4-1.3-1.9-0.10.2-1.4-1.2-1.6-0.10.10.4
Number of responses in last shaping day1.61.74.0-1.6-1.8-1.4-2.0-0.3-0.2-1.5-1.5-1.80.5-0.50.2
Context. condit. distance diff. score0.50.61.4-1.0-1.2-0.9-0.90.00.1-0.9-0.6-1.20.2-0.20.0
Locomotion velocity, session 10.40.51.00.50.80.61.0-0.8-0.50.60.21.00.7-0.70.6
Locomotion distance, session 10.40.52.0-0.0-0.40.0-0.70.91.0-0.10.2-1.0-0.70.7-1.4
Locomotion velocity, session 20.50.61.2-0.4-0.1-0.5-0.4-1.0-1.1-0.3-0.80.21.0-1.01.1
Locomotion distance, session 21.52.13.3-1.5-1.4-1.5-1.7-1.4-1.2-1.7-1.8-1.41.4-1.40.2
Locomotion velocity, session 30.10.20.4-0.3-0.2-0.2-0.4-0.5-0.4-0.3-0.5-0.20.6-0.60.3
Locomotion distance, session 31.92.15.0-0.7-1.4-0.6-2.01.61.6-0.7-0.1-2.2-1.31.3-2.1
Stereotopy head waving bouts, day 31.11.34.00.81.41.11.6-1.0-1.10.90.52.00.7-0.70.8
Stereotopy head waving duration, day 31.21.54.10.71.30.81.6-1.4-1.60.60.12.01.0-1.01.3
Locomotion velocity, session 70.40.41.3-0.5-0.8-0.3-1.00.60.7-0.4-0.2-1.2-0.40.4-0.7
Locomotion distance, session 70.10.20.50.40.20.5-0.20.50.70.30.3-0.2-0.10.1-0.7
Stereotopy head waving bouts, day 71.51.72.6-1.6-1.5-1.6-1.4-1.0-1.1-1.5-1.6-1.00.8-0.81.2
Stereotopy head waving duration, day 71.61.93.1-1.5-1.1-1.5-0.6-1.7-1.8-1.4-1.5-0.31.5-1.51.5
Locomotion velocity, session 83.64.45.9-2.3-2.0-2.2-1.5-2.1-2.0-2.3-2.4-1.32.2-2.22.3
Locomotion distance, session 81.92.84.9-1.9-2.1-2.0-2.2-0.8-0.7-2.1-2.0-2.11.2-1.20.5
Degree of sensitization distance0.90.92.31.01.20.91.4-0.6-0.40.80.51.50.5-0.51.1
Degree of sensitization stereotypy2.42.64.2-2.0-1.9-2.0-1.8-1.1-1.1-1.9-2.0-1.41.0-1.01.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.2-0.3-0.2-0.4-0.6-0.6-0.4-0.10.4-0.40.0
Condit. Reinf. active-inactive response ratio0.40.41.30.61.00.61.0-0.4-0.80.40.31.10.2-0.20.1
Condit. Reinf. active responses1.82.23.1-1.6-1.3-1.6-0.9-1.7-1.8-1.7-1.7-0.81.7-1.70.8
Condit. Reinf. inactive responses3.44.06.1-2.5-2.3-2.4-1.9-1.7-1.6-2.2-2.3-1.81.9-1.91.1
Incentive salience index mean0.30.40.7-0.7-0.6-0.6-0.6-0.5-0.7-0.9-0.7-0.50.5-0.50.0
Condit. Reinf. lever presses0.40.51.2-0.9-0.9-0.8-1.1-0.2-0.3-0.9-0.8-0.90.1-0.1-0.2
Time in familiar zone, hab. session 12.52.44.21.91.91.92.00.80.91.81.81.4-0.70.7-1.6
Time in novel zone, hab. session 13.23.15.1-1.9-1.8-1.8-2.2-1.3-1.6-2.1-2.3-1.31.1-1.12.1
Total zone transitions, hab. session 10.30.41.0-0.7-0.8-0.5-0.9-0.00.0-0.8-0.6-1.00.2-0.2-0.3
Total locomotion distance, hab. session 10.30.41.10.2-0.00.3-0.91.10.70.10.1-0.2-1.11.10.0
Locomotion velocity, hab. session 10.20.30.70.40.30.5-0.40.80.50.40.20.2-0.80.80.3
Time in familiar zone, hab. session 21.71.82.91.71.61.61.11.50.91.41.51.3-1.31.3-0.2
Time in novel zone, hab. session 20.70.71.5-1.0-0.8-0.8-0.5-1.2-0.8-0.8-1.0-0.51.0-1.00.2
Total zone transitions, hab. session 22.43.14.7-1.5-1.1-1.7-1.3-2.0-2.1-1.8-2.2-0.72.1-2.11.8
Total locomotion distance, hab. session 20.81.12.7-1.0-1.0-1.2-1.6-0.3-0.8-1.3-1.4-0.90.3-0.31.3
Locomotion velocity, hab. session 20.60.91.8-0.9-0.8-1.0-1.4-0.4-0.9-1.2-1.3-0.60.4-0.41.3
Novel to familiar place preference ratio0.20.20.3-0.4-0.6-0.4-0.50.40.4-0.2-0.1-0.6-0.40.4-0.1
Novelty place preference0.20.20.4-0.5-0.7-0.4-0.60.30.3-0.4-0.2-0.6-0.30.30.2
Time in novel zone, NPP test0.30.30.7-0.7-0.8-0.6-0.70.10.2-0.5-0.4-0.7-0.10.10.3
Total zone transitions, NPP test0.00.10.30.00.00.1-0.1-0.2-0.1-0.1-0.1-0.20.4-0.4-0.5
Total locomotion distance, NPP test1.31.83.21.41.11.40.21.81.61.31.30.4-1.71.7-1.1
Locomotion velocity, NPP test1.42.03.41.51.21.50.31.81.61.41.40.6-1.81.8-1.0
Pavlov. Cond. lever latency0.50.61.10.90.70.81.00.70.80.81.00.4-0.60.6-1.0
Pavlov. Cond. magazine entry latency0.40.52.5-0.00.2-0.2-0.7-0.6-0.9-0.2-0.90.30.6-0.61.6
Pavlov. Cond. change in total contacts1.61.84.4-1.4-1.4-1.5-2.1-0.6-0.8-1.5-1.7-1.40.6-0.61.3
Pavlov. Cond. index score0.60.82.8-0.5-0.2-0.6-1.0-0.9-1.2-0.6-1.2-0.00.9-0.91.7
Pavlov. Cond. latency score0.60.82.0-0.6-0.4-0.7-1.2-0.7-1.0-0.7-1.2-0.30.7-0.71.4
Pavlov. Cond. lever contacts0.30.31.2-0.6-0.5-0.6-1.1-0.1-0.5-0.5-0.7-0.40.3-0.30.7
Pavlov. Cond. magazine entry number0.50.62.20.30.10.51.00.81.00.51.1-0.0-0.70.7-1.5
Pavlov. Cond. intertrial magazine entries0.40.51.5-0.7-0.5-0.50.1-0.9-0.8-0.5-0.5-0.11.2-1.20.3
Pavlov. Cond. lever-magazine prob. diff.0.91.13.3-0.7-0.4-0.8-1.2-1.0-1.3-0.8-1.4-0.10.9-0.91.8
Pavlov. Cond. response bias0.20.31.20.20.40.1-0.4-0.4-0.70.1-0.50.50.4-0.41.1
Bone: apparent density1.11.92.81.51.41.51.41.21.21.71.71.0-1.31.3-1.3
Bone surface1.01.73.40.80.40.90.11.71.81.01.3-0.4-1.81.8-1.9
Bone volume1.32.24.21.20.81.20.61.81.91.41.60.0-1.81.8-2.1
Bone: connectivity density0.20.30.60.60.50.60.30.70.60.70.60.2-0.70.7-0.5
Bone: cortical apparent density1.31.73.0-1.3-1.1-1.3-0.6-1.6-1.3-1.3-1.4-0.71.7-1.70.8
Bone: cortical area1.11.62.41.41.01.40.71.31.51.31.40.4-1.41.4-1.6
Bone: cortical porosity3.13.45.2-2.2-2.0-2.2-2.1-1.5-1.6-2.1-2.3-1.31.1-1.11.9
Bone: cortical porosity3.84.16.3-2.4-2.3-2.5-2.3-1.7-1.7-2.3-2.5-1.61.3-1.31.9
Bone: cortical thickness0.50.91.51.21.11.21.00.50.71.21.10.8-0.70.7-0.8
Bone: cortical thickness0.40.41.20.20.50.20.8-1.1-0.80.1-0.10.80.8-0.80.3
Bone: cortical tissue density1.52.03.5-1.5-1.2-1.4-0.7-1.7-1.4-1.5-1.5-0.81.9-1.91.0
Bone: elastic displacement0.30.30.90.80.90.80.7-0.00.10.60.51.00.0-0.00.2
Bone: elastic work1.51.93.11.51.21.40.71.41.51.31.50.5-1.81.8-1.5
Bone: endosteal estimation0.81.83.81.00.51.00.01.91.81.11.3-0.2-1.91.9-1.7
Bone: endosteal perimeter0.61.23.10.5-0.00.5-0.51.71.70.50.8-0.7-1.61.6-1.3
Bone: final force1.01.74.10.80.50.90.21.51.50.91.2-0.3-1.91.9-2.0
Bone: final moment1.42.35.11.10.71.20.41.71.81.21.6-0.1-2.12.1-2.3
Bone: marrow area0.91.93.91.10.61.10.12.01.81.21.3-0.1-1.91.9-1.6
Bone: maximum diameter0.91.62.71.10.71.10.51.51.61.01.40.1-1.71.7-1.5
Bone: maximum force1.62.86.31.10.61.20.22.02.11.21.6-0.4-2.52.5-2.5
Bone: maximum moment1.93.37.31.30.71.40.32.22.31.41.8-0.3-2.62.6-2.7
Bone: minimum diameter1.22.35.10.5-0.20.5-0.92.32.20.60.9-1.2-2.22.2-1.9
Bone: periosteal estimation1.32.74.41.51.01.50.52.02.11.51.70.1-2.12.1-2.1
Bone: periosteal perimeter0.81.31.91.31.01.30.61.31.41.21.30.5-1.31.3-0.9
Bone: post-yield work1.11.52.9-0.4-0.9-0.3-1.31.71.5-0.30.2-1.6-1.61.6-1.3
Bone: stiffness0.91.44.40.50.10.50.11.31.30.71.0-0.6-1.71.7-2.1
Bone: tissue strength1.71.73.90.0-0.60.1-0.81.81.70.10.7-1.2-2.02.0-1.8
Bone: trabecular number1.11.73.60.80.50.90.31.71.61.01.3-0.2-1.81.8-1.9
Bone: trabecular spacing0.30.41.20.70.80.70.50.30.10.80.41.1-0.30.30.8
Bone: trabecular thickness0.10.11.00.10.10.10.5-0.10.30.10.3-0.1-0.00.0-1.0
Bone: trabecular tissue density1.92.76.21.01.71.12.4-1.7-1.41.00.42.51.7-1.71.8
Breakpoint value in progressive ratio session0.60.71.5-0.2-0.5-0.2-1.10.90.7-0.6-0.0-1.2-1.11.1-1.2
Distance traveled before self-admin0.00.00.10.10.20.10.1-0.10.10.30.00.30.3-0.30.3
Distance traveled after self-admin1.82.04.40.90.41.1-0.42.12.10.91.1-0.4-2.12.1-1.3
Delta time in closed arm before/after self-admin2.52.54.11.51.11.51.01.81.71.51.80.4-1.91.9-2.0
Delta time in open arm before/after self-admin0.50.51.5-0.5-0.1-0.4-0.1-0.9-0.8-0.1-0.60.51.0-1.01.2
Diff in mean of infusions in LGA sessions1.31.42.5-1.3-1.2-1.2-1.3-0.7-1.0-1.6-1.4-1.21.0-1.01.2
Extinction: sum of active levers before priming3.13.14.31.91.61.91.31.91.91.72.10.6-2.02.0-1.9
Active lever presses in extinction session 64.64.46.92.62.52.62.21.41.42.62.52.0-1.61.6-1.3
Delta distance traveled before/after self-admin2.42.65.81.00.51.1-0.22.42.20.91.4-0.6-2.32.3-1.9
Delta ambulatory time before/after self-admin2.83.16.81.00.31.1-0.32.62.40.91.5-0.7-2.62.6-2.1
Time in closed arm before self-admin2.83.24.4-2.1-1.8-2.0-1.3-1.9-1.6-2.0-2.1-1.11.8-1.81.9
Time in closed arm after self-admin0.20.20.5-0.6-0.7-0.6-0.4-0.0-0.0-0.6-0.3-0.7-0.20.2-0.3
Time in open arm before self-admin4.54.87.22.52.12.41.22.42.12.32.31.1-2.72.7-1.8
Time in open arm after self-admin1.11.22.11.21.11.30.41.21.11.51.10.8-1.21.2-0.4
Sum of active levers in priming session hrs 5-60.10.10.50.40.30.50.20.40.40.10.40.0-0.30.3-0.7
Time to tail flick, vehicle, before self-admin0.90.91.3-1.1-0.9-1.0-0.6-1.1-1.0-0.9-1.0-0.31.1-1.10.6
Time to tail flick, vehicle, after self-admin0.20.21.6-0.3-0.1-0.2-0.2-0.3-0.5-0.1-0.30.30.0-0.01.3
Time to tail flick, test, before self-admin2.32.35.1-2.0-2.2-1.9-2.0-0.30.0-1.8-1.5-2.20.4-0.4-0.3
Time to tail flick, test, after self-admin0.10.10.3-0.4-0.4-0.4-0.50.10.1-0.3-0.3-0.4-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA0.30.30.90.30.20.4-0.10.80.50.50.40.2-1.01.00.7
Delta time to tail flick, test, before/after SA1.41.23.91.21.61.21.4-0.3-0.61.20.72.00.3-0.30.9
Ambulatory time before self-admin0.10.10.3-0.1-0.0-0.1-0.1-0.3-0.2-0.0-0.20.20.4-0.40.5
Ambulatory time after self-admin3.33.78.21.00.31.1-0.72.92.80.81.5-1.0-2.92.9-2.3
Total heroin consumption0.30.31.0-0.4-0.6-0.4-0.90.40.4-0.7-0.3-1.0-0.30.3-0.5
Area under the delay curve0.60.61.5-0.6-0.8-0.8-1.10.20.1-0.9-0.5-1.2-0.80.8-0.5
Delay disc. indifference point, 0s delay1.92.15.7-1.7-2.1-1.7-1.8-0.00.3-1.8-1.1-2.4-0.20.2-1.2
Delay disc. indifference point, 16s delay0.90.91.8-0.8-1.0-0.9-1.40.40.2-0.9-0.5-1.3-1.21.2-0.5
Delay disc. indifference point, 2s delay0.91.03.2-0.4-0.8-0.4-1.10.91.1-0.60.0-1.6-0.90.9-1.8
Delay disc. indifference point, 24s delay1.21.22.90.1-0.3-0.0-0.91.31.1-0.10.4-1.1-1.71.7-1.6
Delay disc. indifference point, 4s delay0.70.81.8-1.0-1.0-1.1-1.3-0.5-0.5-1.2-1.1-1.0-0.10.10.4
Delay disc. indifference point, 8s delay0.10.20.60.0-0.1-0.1-0.40.30.3-0.1-0.0-0.4-0.80.80.0
Delay discount exponential model param0.40.51.00.30.50.51.0-0.3-0.20.70.31.01.0-1.00.5
Delay discount hyperbolic model param0.50.51.20.40.60.61.0-0.2-0.20.80.41.10.8-0.80.6
Fecal boli incidents, locomotor time 11.41.64.0-0.7-0.1-0.70.0-1.9-2.0-0.9-1.10.61.6-1.61.8
Change in fecal boli incidents, locomotor task1.11.02.11.31.41.21.40.20.01.11.01.4-0.50.5-0.4
Time >=10cm from walls, locomotor time 10.00.00.1-0.2-0.10.00.3-0.2-0.3-0.00.00.1-0.30.30.1
Bouts of movement, locomotor time 10.91.02.8-0.8-1.2-1.0-1.70.60.7-1.0-0.6-1.7-0.70.7-0.7
Total resting periods, locomotor time 10.70.72.2-0.7-1.0-0.9-1.50.50.5-0.9-0.6-1.4-0.60.6-0.5
Rest time, locomotor task time 10.70.82.3-0.7-0.3-0.60.0-1.4-1.5-0.8-0.80.30.9-0.90.9
Distance moved, locomotor task time 10.10.10.40.30.00.2-0.00.60.70.20.2-0.40.1-0.1-0.5
Vertical activity count, locomotor time 11.01.02.90.90.40.6-0.51.71.60.70.8-0.5-1.21.2-1.1
Time >=10cm from walls, locomotor time 21.41.52.8-1.0-0.7-1.1-0.6-1.6-1.7-1.3-1.4-0.21.4-1.41.2
Bouts of movement, locomotor time 20.10.10.3-0.1-0.1-0.4-0.50.10.2-0.1-0.3-0.2-0.30.30.3
Total resting periods, locomotor time 20.10.10.4-0.00.0-0.3-0.5-0.1-0.1-0.1-0.40.0-0.10.10.7
Rest time, locomotor task time 20.40.41.4-0.4-0.0-0.4-0.2-0.9-1.2-0.5-0.70.40.5-0.51.1
Distance moved, locomotor task time 20.20.20.7-0.3-0.5-0.4-0.50.00.3-0.4-0.3-0.80.4-0.4-0.5
Vertical activity count, locomotor time 20.60.62.20.2-0.2-0.0-0.61.01.20.10.3-0.9-0.80.8-1.5
Weight adjusted by age0.30.30.60.70.50.60.50.50.60.50.60.2-0.60.6-0.8
Seeking ratio, delayed vs. immediate footshock1.11.22.5-0.5-1.1-0.7-1.21.01.2-0.7-0.1-1.6-1.31.3-1.4
Locomotion in novel chamber0.20.30.9-0.10.2-0.10.2-0.5-1.0-0.1-0.30.70.7-0.70.9
Locomotion in novel chamber post-restriction0.10.10.50.10.2-0.00.0-0.0-0.5-0.0-0.10.30.0-0.00.7
Progressive ratio0.10.10.3-0.4-0.3-0.2-0.6-0.1-0.1-0.2-0.4-0.1-0.00.00.5
Food seeking constrained by brief footshock1.31.63.90.80.41.0-0.31.81.71.01.1-0.0-2.02.0-1.2
Seeking ratio, punishment vs. effort0.30.41.00.0-0.20.0-0.30.90.80.10.3-0.5-0.90.9-1.0
Run reversals in cocaine runway, females0.50.51.90.3-0.10.1-0.20.91.20.00.4-0.7-0.70.7-1.4
Run reversals in cocaine runway, males2.62.56.91.72.11.92.3-0.0-0.51.91.42.6-0.20.20.7
Latency to leave start box in cocaine runway0.50.51.5-0.6-0.9-0.6-0.70.20.7-0.6-0.2-1.2-0.00.0-1.2
Latency to leave start box in cocaine runway, F0.50.61.5-0.8-1.0-0.9-0.9-0.10.2-0.9-0.4-1.2-0.00.0-1.2
Latency to leave start box in cocaine runway, M0.10.10.30.10.00.30.30.10.50.30.3-0.00.2-0.20.1
Cd content in liver0.30.30.50.60.60.60.70.20.60.60.60.6-0.40.40.4
Co content in liver0.20.20.5-0.3-0.1-0.30.2-0.5-0.7-0.3-0.30.20.7-0.70.6
Cu content in liver0.30.30.90.2-0.00.20.10.70.80.30.6-0.3-0.80.8-1.0
Fe content in liver0.10.10.3-0.4-0.3-0.4-0.2-0.1-0.2-0.4-0.3-0.20.1-0.10.6
K content in liver0.10.10.3-0.3-0.2-0.2-0.50.0-0.4-0.3-0.3-0.10.1-0.10.1
Mg content in liver0.40.41.5-0.4-0.0-0.4-0.1-0.7-1.2-0.4-0.60.40.9-0.90.6
Mn content in liver0.80.92.70.10.60.10.6-1.1-1.40.1-0.41.31.0-1.01.6
Na content in liver0.60.71.50.0-0.40.0-0.81.01.2-0.00.2-0.9-1.01.0-1.2
Rb content in liver0.70.91.8-1.3-1.3-1.3-1.0-0.2-0.6-1.3-0.9-1.20.4-0.4-0.1
Se content in liver3.84.610.8-1.5-0.6-1.50.2-3.2-3.3-1.4-1.90.73.0-3.02.3
Sr content in liver0.50.51.40.00.40.00.4-0.9-1.00.0-0.40.80.8-0.81.2
Zn content in liver0.10.10.3-0.4-0.3-0.4-0.1-0.3-0.5-0.4-0.3-0.20.3-0.3-0.4