Hub : Genes

Tgfbrap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024562 0.14 0.08 2.2e-16 0.11 0.11 0.1 0.11 6.3e-12 4.9e-12 2.0e-11 8.6e-12
2 Adipose mRNA stability ENSRNOG00000024562 0.21 0.11 5.6e-17 0.12 0.11 0.12 0.12 3.9e-13 1.6e-12 8.7e-13 6.6e-13
3 BLA gene expression ENSRNOG00000024562 0.28 0.24 6.9e-08 0.11 0.15 0.13 0.14 1.6e-06 1.5e-08 2.1e-07 7.7e-08
4 BLA mRNA stability ENSRNOG00000024562 0.09 0.06 2.2e-05 0.09 0.1 0.11 0.1 1.6e-05 9.3e-06 2.1e-06 8.9e-06
5 Brain mRNA stability ENSRNOG00000024562 0.05 0.04 8.8e-05 0.04 0.03 0.04 0.04 1.1e-04 5.4e-04 2.9e-04 3.4e-04
6 Eye gene expression ENSRNOG00000024562 0.43 0.18 1.8e-04 0.16 0.1 0.11 0.11 2.0e-03 1.3e-02 1.0e-02 8.2e-03
7 Liver gene expression ENSRNOG00000024562 0.1 0.05 6.6e-12 0.07 0.06 0.07 0.07 1.8e-08 1.5e-07 3.5e-08 6.3e-08
8 Liver intron excision ratio chr9:45348544:45353406 0.17 0.1 0.0e+00 0.12 0.11 0.11 0.11 3.5e-13 1.4e-12 1.6e-12 1.9e-12
9 Liver intron excision ratio chr9:45348544:45365056 0.03 0.02 1.2e-03 0 0.01 0 0 1.6e-01 7.1e-02 1.2e-01 1.8e-01
10 OFC gene expression ENSRNOG00000024562 0.35 0.28 7.3e-04 0.09 0.1 0.1 0.1 4.1e-03 1.9e-03 2.1e-03 1.9e-03
11 OFC mRNA stability ENSRNOG00000024562 0.17 0.11 4.6e-03 0.08 0.09 0.09 0.01 6.1e-03 4.2e-03 4.4e-03 1.6e-01
12 PL gene expression ENSRNOG00000024562 0.05 0.05 2.2e-03 0.03 0.03 0.02 0.02 2.5e-03 1.8e-03 1.3e-02 6.5e-03
13 PL mRNA stability ENSRNOG00000024562 0.06 0.04 3.4e-04 0.04 0.04 0.04 0.04 2.9e-04 3.9e-04 9.7e-04 8.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.65.36.8-2.2-2.62.02.52.42.42.42.4-2.01.42.52.42.6
BMI without tail0.00.00.10.10.10.10.1-0.0-0.2-0.2-0.2-0.0-0.1-0.2-0.1-0.0
Body weight0.00.10.40.1-0.4-0.10.60.00.00.20.20.1-0.00.20.00.1
Epididymis fat weight0.10.10.4-0.3-0.60.40.50.20.10.20.3-0.20.40.30.40.5
Glucose0.10.10.30.20.3-0.1-0.6-0.4-0.4-0.3-0.4-0.10.4-0.4-0.5-0.3
Heart weight0.81.21.5-1.1-1.21.20.90.91.11.21.2-1.11.01.11.11.1
Left kidney weight0.00.10.30.0-0.50.00.1-0.10.20.30.30.2-0.50.10.10.1
Right kidney weight0.41.03.21.20.1-1.4-0.5-1.0-0.7-0.6-0.61.6-1.8-0.7-0.7-0.9
Tail length0.72.13.31.31.5-1.0-1.2-1.6-1.8-1.6-1.61.0-0.4-1.7-1.7-1.8
Length with tail0.41.52.41.31.1-1.2-0.9-1.4-1.3-1.1-1.11.2-0.8-1.3-1.3-1.5
Length without tail0.30.61.1-0.4-1.00.10.80.71.01.01.1-0.1-0.20.90.80.7
Liver weight, left0.30.51.40.60.6-0.7-1.1-0.6-0.6-0.6-0.60.7-1.2-0.6-0.6-0.6
Liver weight, right0.20.40.60.60.5-0.5-0.7-0.6-0.7-0.8-0.80.5-0.2-0.6-0.6-0.5
Parametrial fat weight0.00.00.10.20.1-0.20.1-0.2-0.2-0.2-0.20.1-0.2-0.1-0.2-0.1
Retroperitoneal fat weight0.00.20.5-0.1-0.6-0.20.70.40.30.40.40.1-0.50.50.40.2
Intraocular pressure1.62.33.0-1.4-1.51.41.71.51.51.71.7-1.41.31.61.51.5
Extensor digitorum longus weight6.325.231.3-4.9-5.24.25.25.35.45.65.5-3.92.45.55.65.5
Soleus weight1.02.94.1-1.6-1.91.41.51.81.82.01.9-1.10.31.92.02.0
Tibialis anterior weight3.010.513.7-3.2-3.62.83.13.43.43.63.5-2.41.53.53.73.6
Tibia length0.71.92.71.51.6-1.5-1.2-1.3-1.2-1.2-1.21.4-1.7-1.2-1.4-1.3
Number of licking bursts0.00.00.1-0.20.30.3-0.2-0.00.00.10.1-0.30.1-0.1-0.00.0
Food consumed during 24 hour testing period0.40.50.7-0.7-0.70.70.80.70.70.70.7-0.80.60.80.70.8
Times rat made contact with spout0.20.20.7-0.00.60.3-0.4-0.4-0.4-0.4-0.4-0.50.8-0.5-0.5-0.4
Mean time between licks in bursts1.01.42.0-1.1-1.40.90.71.41.31.21.2-0.8-0.31.31.41.4
Mean num. licks in bursts0.10.10.3-0.2-0.40.20.40.20.20.10.1-0.30.60.30.20.2
Std. dev. time between licks in bursts0.70.81.2-1.0-0.61.00.41.11.01.01.0-1.00.21.01.01.1
Water consumed over 24 hours0.10.10.4-0.3-0.30.40.50.20.20.20.2-0.40.70.30.20.3
Indifference point 0 sec0.10.20.9-0.1-0.8-0.2-0.30.30.40.50.50.3-0.90.40.50.1
Indifference point AUC0.60.71.3-0.8-1.10.80.80.70.90.80.8-0.91.00.90.70.9
Indifference point function ln k1.01.42.0-1.3-0.91.30.81.31.41.31.3-1.10.21.21.41.2
Indifference point function log k1.01.42.0-1.3-0.91.30.81.31.41.31.3-1.10.21.21.41.2
Delay discounting total patch changes 0 sec0.20.31.0-0.3-1.00.1-0.10.40.60.60.6-0.1-0.60.60.60.3
Delay discounting total patch changes 12 sec0.50.72.00.90.1-1.1-1.0-0.8-0.6-0.5-0.61.1-1.4-0.5-0.6-0.8
Delay discounting total patch changes 18 sec0.81.02.4-1.0-1.60.90.60.91.11.11.1-0.90.81.11.00.9
Delay discounting total patch changes 24 sec0.10.10.40.2-0.6-0.5-0.2-0.20.20.10.00.5-0.60.10.1-0.0
Delay discounting total patch changes 6 sec0.10.10.6-0.0-0.8-0.2-0.40.20.10.10.10.2-0.40.20.20.0
Delay discounting time to switch 0 sec0.81.21.51.21.1-1.1-1.0-1.2-1.0-1.0-1.01.2-1.1-1.1-1.1-1.1
Delay discounting water rate 0 sec0.61.01.8-1.1-1.11.10.91.10.70.80.8-1.31.31.00.80.8
Delay discounting water rate 12 sec0.40.60.9-1.0-0.80.90.30.80.70.70.7-0.90.70.70.80.8
Delay discounting water rate 18 sec0.00.00.1-0.3-0.30.3-0.20.3-0.0-0.00.0-0.2-0.00.00.20.0
Delay discounting water rate 24 sec0.30.40.6-0.7-0.70.70.40.80.50.60.6-0.70.70.60.70.7
Delay discounting water rate 6 sec0.91.32.1-1.4-0.81.50.91.31.01.01.0-1.31.11.11.21.1
Locomotor activity0.10.10.20.30.2-0.2-0.3-0.5-0.4-0.4-0.40.20.1-0.4-0.4-0.4
Locomotor testing distance1.11.82.31.31.3-1.2-1.4-1.5-1.4-1.4-1.51.2-0.9-1.5-1.4-1.4
Locomotor testing rearing1.62.52.91.71.5-1.6-1.5-1.7-1.6-1.6-1.71.7-1.3-1.7-1.6-1.6
Light reinforcement 11.83.36.4-1.6-2.51.21.71.82.02.02.0-1.30.82.11.91.8
Light reinforcement 20.40.61.5-0.7-1.20.50.40.80.90.90.9-0.70.20.90.70.6
Reaction time number correct1.01.52.0-1.2-1.21.01.01.41.41.31.3-1.00.51.41.41.4
Reaction time mean minus median0.70.81.50.81.0-0.5-1.2-0.9-1.0-1.1-1.10.6-0.4-1.1-1.0-0.8
Reaction time mean minus median AUC0.50.61.10.70.8-0.4-1.0-0.8-0.9-0.9-0.90.6-0.4-1.0-0.8-0.7
Reaction time num false alarms1.62.23.9-1.4-1.71.22.01.61.41.61.5-1.11.11.61.51.5
Reaction time num false alarms AUC2.02.84.6-1.6-1.71.32.11.81.81.81.8-1.30.91.91.81.7
Reaction time trials correct on left1.01.52.0-1.2-1.21.01.01.41.41.31.3-1.00.51.41.41.4
Reaction time trials on left1.01.41.9-1.2-1.11.00.91.41.31.31.2-1.00.41.31.31.3
Reaction time mean1.52.13.21.31.4-1.0-1.5-1.6-1.6-1.8-1.71.0-0.1-1.7-1.7-1.6
Reaction time mean AUC1.01.42.21.01.1-0.8-1.1-1.3-1.3-1.5-1.40.70.1-1.4-1.4-1.3
Median of all reaction times1.41.92.91.21.3-1.0-1.2-1.5-1.5-1.7-1.60.90.1-1.6-1.6-1.6
Reaction time omissions0.60.91.20.81.1-0.6-1.1-1.0-0.9-1.1-1.10.7-0.8-1.0-0.9-0.8
Reaction time false alarm rate0.50.71.9-0.7-0.90.61.40.90.91.01.0-0.50.50.90.90.7
Reaction time premature initiation rate0.20.30.40.60.1-0.6-0.6-0.5-0.6-0.6-0.60.6-0.3-0.5-0.5-0.1
Reaction time premature initiations0.00.00.2-0.0-0.4-0.1-0.10.10.10.10.10.0-0.10.20.10.5
Std. dev. reaction times1.11.52.41.11.4-0.8-1.5-1.2-1.3-1.5-1.40.9-0.7-1.4-1.3-1.2
Reaction time trials completed1.01.41.9-1.2-1.11.00.91.41.31.31.2-1.00.41.31.31.3
Reaction time trials AUC0.91.31.8-1.2-1.11.00.91.31.31.21.2-1.00.51.31.31.3
Social response proportion0.30.30.80.60.2-0.4-0.2-0.9-0.7-0.6-0.60.30.4-0.6-0.7-0.5
Social responses0.91.21.81.10.9-0.8-0.8-1.3-1.3-1.3-1.30.70.0-1.2-1.3-1.2
Social time4.76.27.72.52.5-2.2-2.6-2.8-2.7-2.5-2.52.1-1.4-2.7-2.8-2.8
Conditioned locomotion0.91.01.61.11.0-0.8-0.9-1.2-1.2-1.2-1.10.6-0.1-1.1-1.3-1.1
Cocaine response after cond. corrected0.80.91.8-1.1-0.71.20.90.90.80.80.8-1.41.30.90.70.9
Cocaine response after cond. not corrected0.50.61.0-0.8-0.60.90.80.70.70.70.6-1.00.90.70.60.7
Cocaine response before conditioning0.10.10.60.5-0.1-0.6-0.0-0.2-0.2-0.2-0.20.8-0.8-0.2-0.1-0.3
Saline control response0.10.10.50.30.1-0.50.1-0.00.00.10.10.5-0.70.10.00.0
Condit. Reinf. active minus inactive responses0.10.10.70.10.30.10.0-0.4-0.4-0.4-0.4-0.20.8-0.4-0.4-0.4
Condit. Reinf. active-inactive response ratio1.01.01.50.90.9-0.7-0.8-1.2-1.2-1.2-1.20.60.3-1.2-1.2-1.1
Condit. Reinf. active responses0.20.30.8-0.6-0.30.70.50.40.40.40.4-0.80.90.40.40.4
Condit. Reinf. inactive responses1.01.21.7-1.1-1.01.00.91.31.31.31.3-0.90.21.21.31.2
Condit. Reinf. lever presses0.10.10.20.20.4-0.1-0.4-0.4-0.3-0.3-0.30.1-0.1-0.4-0.3-0.2
Condit. Reinf. lever reinforcers received0.40.61.2-0.9-0.51.00.70.60.70.60.7-1.01.10.60.60.7
Pavlov. Cond. lever latency0.20.30.5-0.5-0.40.50.70.60.60.60.6-0.60.50.60.50.5
Pavlov. Cond. magazine entry latency0.60.61.50.90.3-1.1-0.7-0.6-0.7-0.7-0.71.2-1.1-0.7-0.5-0.6
Pavlov. Cond. change in total contacts0.30.40.90.50.7-0.4-0.9-0.6-0.6-0.7-0.60.4-0.5-0.7-0.6-0.6
Pavlov. Cond. index score0.40.50.90.70.4-0.8-0.9-0.7-0.7-0.8-0.80.8-0.7-0.7-0.7-0.6
Pavlov. Cond. latency score0.20.30.50.50.2-0.6-0.7-0.5-0.5-0.6-0.60.6-0.5-0.5-0.4-0.4
Pavlov. Cond. lever contacts0.60.81.60.80.8-0.8-1.3-0.9-0.9-0.9-0.90.9-0.9-1.0-0.8-0.8
Pavlov. Cond. magazine entry number0.70.91.5-1.0-0.61.11.00.90.91.01.0-1.21.00.90.80.9
Pavlov. Cond. intertrial magazine entries3.54.55.6-2.1-2.22.12.42.12.12.22.2-2.11.92.22.12.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.60.3-0.7-0.8-0.6-0.6-0.6-0.60.7-0.7-0.6-0.5-0.5
Pavlov. Cond. response bias1.21.72.81.21.1-1.4-1.5-1.2-1.2-1.2-1.21.5-1.7-1.2-1.0-1.1
Conditioned reinforcement - actives0.30.31.3-0.5-0.70.60.80.20.20.00.0-0.61.20.20.30.0
Conditioned reinforcement - inactives0.20.20.40.5-0.4-0.40.0-0.6-0.7-0.6-0.60.40.4-0.5-0.5-0.4
Conditioned locomotion0.30.31.7-0.3-1.30.20.80.40.40.20.2-0.30.60.60.40.5
Intermittent access intake day 1-15 change0.00.00.00.1-0.00.0-0.1-0.1-0.1-0.2-0.20.2-0.2-0.10.0-0.1
Intermittent access intake escalation0.20.20.30.50.4-0.3-0.3-0.6-0.6-0.5-0.50.5-0.2-0.6-0.4-0.5
Intermittent access intake escalation 20.20.20.40.40.4-0.2-0.3-0.6-0.5-0.6-0.60.4-0.1-0.6-0.4-0.6
Intermitt. access day 1 inactive lever presses1.31.41.81.30.9-1.3-1.1-1.2-1.3-1.1-1.11.2-0.9-1.1-1.2-1.1
Intermitt. access day 15 inactive lever presses0.30.30.70.60.1-0.7-0.3-0.5-0.6-0.4-0.40.8-0.8-0.5-0.4-0.2
Intermitt. access escalation Index0.10.10.50.10.5-0.20.70.00.0-0.2-0.20.1-0.2-0.0-0.0-0.0
Intermittent access day 1 total infusions0.40.43.2-0.4-0.80.70.5-0.1-0.2-0.2-0.2-0.91.80.0-0.2-0.1
Intermittent access day 15 total infusions0.20.31.50.0-0.30.30.2-0.5-0.5-0.6-0.6-0.31.2-0.4-0.4-0.4
Intermittent access terminal intake (last 3 days)0.30.31.9-0.3-0.80.60.5-0.2-0.2-0.3-0.3-0.61.4-0.1-0.1-0.1
Intermittent access total infusions0.30.42.6-0.3-0.70.70.4-0.2-0.2-0.3-0.3-0.71.6-0.1-0.1-0.2
Intermittent access day 1 locomotion0.00.00.20.0-0.40.00.2-0.2-0.2-0.1-0.1-0.10.4-0.1-0.2-0.1
Intermittent access day 15 total locomotion0.10.10.3-0.3-0.60.40.60.20.10.30.3-0.30.50.20.30.3
Intermittent access total locomotion0.20.20.4-0.4-0.70.50.50.30.30.30.3-0.50.60.30.30.3
Intermittent access standard deviation1.61.72.81.30.7-1.0-1.1-1.7-1.6-1.7-1.70.90.1-1.4-1.6-1.3
Cocaine induced anxiety1.31.52.6-1.0-1.50.61.61.41.41.41.4-0.50.01.41.41.5
Post-drug Anxiety1.11.23.0-0.9-1.10.71.71.11.11.11.1-0.80.81.21.01.2
Baseline Anxiety0.30.31.20.20.60.0-0.3-0.6-0.6-0.6-0.6-0.41.1-0.5-0.8-0.5
Lifetime Intake0.40.42.9-0.5-1.00.80.60.00.0-0.1-0.1-0.91.70.10.10.0
Incentive Sensitization - Responses0.10.10.40.30.4-0.2-0.2-0.1-0.2-0.3-0.30.6-0.7-0.30.0-0.2
Incentive Sensitization - Breakpoint0.10.10.50.20.3-0.2-0.1-0.0-0.1-0.2-0.20.6-0.7-0.20.1-0.1
Progressive ratio test 1 active lever presses1.01.12.6-1.0-1.61.01.40.70.70.80.8-1.11.50.90.80.6
Progressive ratio test 1 breakpoint0.90.92.3-0.9-1.50.91.30.60.60.70.7-1.01.50.80.60.5
Progressive ratio test 1 inactive lever presses0.91.01.51.20.1-1.2-0.8-1.1-1.1-1.1-1.11.1-0.6-0.9-1.1-1.0
Progressive ratio test 2 active lever presses0.10.10.3-0.2-0.40.40.50.10.10.00.0-0.10.50.10.20.0
Progressive ratio test 2 breakpoint0.30.40.7-0.6-0.80.70.80.50.50.30.3-0.50.70.50.60.4
Progressive ratio test 2 inactive lever presses0.60.71.00.90.3-0.9-0.5-0.9-1.0-0.9-0.91.0-0.7-0.8-0.8-0.8
Total sessions with >9 infusions1.81.94.4-1.4-2.11.31.51.31.21.11.1-1.41.71.41.21.2
Short access day 1 total inactive lever presses0.30.30.70.6-0.5-0.8-0.5-0.5-0.5-0.5-0.50.8-0.7-0.4-0.3-0.5
Short access day 10 total inactive lever presses1.31.52.31.41.0-1.4-1.0-1.2-1.2-1.2-1.21.5-1.3-1.1-1.1-0.9
Short access day 1 total infusions0.30.32.6-0.4-1.60.40.50.30.30.10.1-0.30.70.40.40.2
Short access day 10 total infusions1.21.36.6-1.1-1.31.41.30.40.40.30.3-1.62.60.50.40.4
Short access total infusions0.70.83.0-0.8-1.50.91.10.50.40.30.3-1.11.70.60.50.4
Short access day 1 locomotion0.40.41.2-0.6-1.10.50.70.60.50.50.5-0.60.70.60.50.5
Short access day 10 total locomotion0.10.10.30.3-0.0-0.2-0.3-0.5-0.5-0.3-0.30.2-0.1-0.4-0.4-0.4
Short access total locomotion0.30.30.8-0.5-0.90.30.80.60.50.50.5-0.40.40.60.50.5
Compulsive drug intake0.10.10.40.00.6-0.1-0.5-0.1-0.2-0.2-0.20.1-0.3-0.3-0.1-0.2
One hour access (0.3 mA shock)0.60.73.10.10.20.4-0.2-0.8-0.8-1.0-1.0-0.61.8-0.7-0.8-0.9
One hour access (shock baseline)0.40.52.60.1-0.10.30.2-0.6-0.6-0.7-0.7-0.51.6-0.5-0.7-0.7
Number of responses in last shaping day0.50.50.90.70.3-0.8-0.6-0.7-0.7-0.7-0.70.7-0.2-0.7-0.7-0.9
Context. condit. distance diff. score1.72.02.41.51.5-1.5-1.1-1.4-1.5-1.5-1.51.5-1.2-1.4-1.5-1.5
Locomotion velocity, session 10.00.00.2-0.1-0.10.10.50.00.00.10.1-0.10.50.10.00.0
Locomotion distance, session 10.70.92.4-0.7-1.30.51.50.90.90.90.9-0.40.61.01.01.0
Locomotion velocity, session 23.13.64.5-1.8-1.91.71.92.12.12.12.1-1.50.72.12.12.0
Locomotion distance, session 22.43.44.1-1.8-2.01.61.91.92.01.91.9-1.61.22.01.92.0
Locomotion velocity, session 30.20.20.40.50.3-0.5-0.2-0.4-0.4-0.5-0.50.6-0.6-0.4-0.4-0.4
Locomotion distance, session 30.10.10.30.40.1-0.3-0.3-0.3-0.3-0.6-0.60.4-0.2-0.3-0.3-0.3
Stereotopy head waving bouts, day 30.20.20.50.40.7-0.4-0.7-0.5-0.4-0.3-0.30.3-0.2-0.6-0.5-0.4
Stereotopy head waving duration, day 30.00.00.1-0.00.30.0-0.1-0.2-0.10.00.0-0.10.3-0.2-0.2-0.1
Locomotion velocity, session 70.60.71.3-0.7-0.90.40.71.01.01.01.0-0.2-0.61.01.10.9
Locomotion distance, session 70.70.91.2-1.0-1.00.80.91.01.11.11.1-0.80.21.11.11.1
Stereotopy head waving bouts, day 70.10.10.10.30.4-0.3-0.2-0.3-0.2-0.3-0.30.2-0.1-0.3-0.3-0.4
Stereotopy head waving duration, day 70.30.40.70.70.7-0.8-0.4-0.5-0.5-0.6-0.60.9-0.8-0.6-0.6-0.7
Locomotion velocity, session 80.40.42.30.80.4-0.9-0.4-0.3-0.3-0.4-0.41.1-1.5-0.3-0.3-0.3
Locomotion distance, session 80.10.10.60.2-0.2-0.40.40.20.20.10.10.5-0.80.30.20.2
Degree of sensitization distance2.12.12.6-1.6-1.21.41.31.41.51.61.6-1.51.01.51.51.5
Degree of sensitization stereotypy0.30.30.50.60.4-0.7-0.4-0.5-0.5-0.6-0.60.7-0.6-0.5-0.5-0.6
Condit. Reinf. active minus inactive responses0.60.72.7-0.7-0.60.81.30.40.50.70.7-0.91.70.50.40.6
Condit. Reinf. active-inactive response ratio0.30.42.3-0.4-0.30.51.10.20.20.30.3-0.61.50.20.10.2
Condit. Reinf. active responses0.30.41.1-0.6-0.40.61.10.40.50.60.6-0.71.00.50.40.5
Condit. Reinf. inactive responses0.40.50.7-0.7-0.60.60.80.80.70.80.8-0.60.10.80.80.8
Incentive salience index mean0.10.10.4-0.10.10.10.6-0.1-0.00.20.2-0.20.50.0-0.10.1
Condit. Reinf. lever presses0.70.91.51.01.1-1.1-0.6-0.9-0.9-0.8-0.81.1-1.2-0.9-0.9-0.8
Time in familiar zone, hab. session 10.20.20.90.10.40.10.1-0.4-0.4-0.4-0.4-0.41.0-0.4-0.5-0.4
Time in novel zone, hab. session 10.30.30.70.40.4-0.3-0.8-0.5-0.5-0.6-0.60.4-0.4-0.6-0.5-0.5
Total zone transitions, hab. session 10.30.42.30.60.1-0.8-0.4-0.2-0.2-0.2-0.21.1-1.5-0.3-0.1-0.2
Total locomotion distance, hab. session 10.50.71.0-0.8-1.00.60.81.01.00.90.9-0.50.01.01.01.0
Locomotion velocity, hab. session 10.40.50.8-0.5-0.80.40.50.90.90.80.8-0.2-0.40.90.90.8
Time in familiar zone, hab. session 20.30.30.80.40.6-0.3-0.9-0.5-0.5-0.5-0.50.3-0.4-0.6-0.5-0.5
Time in novel zone, hab. session 20.00.00.20.1-0.0-0.10.4-0.1-0.0-0.1-0.10.10.3-0.0-0.1-0.1
Total zone transitions, hab. session 20.10.20.5-0.3-0.70.30.70.30.30.40.4-0.30.50.40.30.4
Total locomotion distance, hab. session 22.02.73.2-1.7-1.71.71.81.61.61.61.6-1.71.71.61.61.6
Locomotion velocity, hab. session 21.62.22.7-1.5-1.61.41.61.51.51.51.5-1.41.41.51.51.5
Novel to familiar place preference ratio0.20.21.4-0.50.10.70.10.10.10.20.2-0.91.20.1-0.00.1
Novelty place preference0.20.21.2-0.40.20.60.10.00.00.20.2-0.81.10.1-0.10.0
Time in novel zone, NPP test0.20.21.2-0.30.30.5-0.1-0.2-0.2-0.0-0.0-0.71.1-0.1-0.3-0.2
Total zone transitions, NPP test0.40.61.4-0.6-1.00.61.20.70.80.80.8-0.40.50.80.80.9
Total locomotion distance, NPP test1.21.72.0-1.3-1.31.31.41.31.41.31.3-1.21.01.31.41.4
Locomotion velocity, NPP test1.52.22.7-1.4-1.51.31.61.61.61.61.6-1.10.71.51.61.6
Pavlov. Cond. lever latency0.91.21.7-1.3-1.11.20.71.11.01.01.0-1.31.21.11.10.9
Pavlov. Cond. magazine entry latency0.10.10.20.40.3-0.4-0.1-0.4-0.4-0.2-0.20.4-0.1-0.4-0.4-0.2
Pavlov. Cond. change in total contacts0.00.00.1-0.10.10.20.40.10.10.30.3-0.30.20.20.00.2
Pavlov. Cond. index score0.40.50.80.80.9-0.7-0.5-0.8-0.8-0.6-0.60.7-0.4-0.8-0.9-0.7
Pavlov. Cond. latency score0.60.81.01.01.0-0.9-0.6-1.0-0.9-0.8-0.80.9-0.6-0.9-1.0-0.8
Pavlov. Cond. lever contacts0.50.60.90.90.8-0.9-0.6-0.8-0.8-0.7-0.70.9-0.9-0.8-0.8-0.6
Pavlov. Cond. magazine entry number0.60.71.1-0.9-0.90.80.61.01.00.80.8-0.70.11.01.01.0
Pavlov. Cond. intertrial magazine entries0.60.71.1-0.9-0.41.01.00.80.80.70.7-1.00.80.80.70.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.50.5-0.4-0.1-0.5-0.5-0.3-0.30.3-0.1-0.4-0.5-0.4
Pavlov. Cond. response bias0.30.30.50.60.7-0.6-0.3-0.6-0.6-0.4-0.40.5-0.3-0.6-0.7-0.5
Bone: apparent density5.49.010.62.93.3-2.9-3.2-3.0-3.0-3.0-3.02.7-2.6-3.1-3.0-3.1
Bone surface0.81.52.51.11.5-1.1-1.6-1.1-1.1-1.0-1.11.0-1.6-1.1-1.2-1.2
Bone volume2.94.96.32.12.5-2.1-2.5-2.2-2.2-2.1-2.22.0-2.1-2.2-2.2-2.3
Bone: connectivity density1.32.03.41.31.8-1.3-1.8-1.4-1.4-1.3-1.41.1-1.3-1.4-1.5-1.5
Bone: cortical apparent density2.02.63.9-1.3-2.01.01.51.81.81.91.9-0.7-0.11.81.91.9
Bone: cortical area0.10.10.60.30.3-0.4-0.2-0.2-0.1-0.0-0.10.4-0.8-0.1-0.2-0.2
Bone: cortical porosity0.91.01.40.91.2-0.9-1.0-1.0-1.0-1.0-1.10.9-0.8-1.1-1.0-1.1
Bone: cortical porosity1.51.72.31.31.5-1.3-1.2-1.2-1.2-1.2-1.31.3-1.3-1.3-1.3-1.3
Bone: cortical thickness0.10.10.80.40.3-0.4-0.2-0.1-0.10.0-0.00.4-0.9-0.0-0.2-0.1
Bone: cortical thickness0.10.10.40.30.5-0.4-0.2-0.2-0.2-0.1-0.20.3-0.6-0.2-0.3-0.2
Bone: cortical tissue density1.92.53.8-1.3-2.01.01.51.81.71.81.9-0.7-0.11.81.91.8
Bone: elastic displacement0.20.20.60.10.30.2-0.8-0.4-0.4-0.5-0.4-0.20.4-0.4-0.4-0.5
Bone: elastic work0.71.01.30.91.1-0.8-1.0-1.0-1.0-1.0-1.00.7-0.7-1.0-1.1-1.2
Bone: endosteal estimation0.00.10.20.30.4-0.2-0.4-0.3-0.4-0.3-0.30.1-0.2-0.3-0.4-0.3
Bone: endosteal perimeter0.00.00.10.20.3-0.2-0.1-0.3-0.3-0.2-0.20.1-0.1-0.2-0.3-0.2
Bone: final force0.20.21.20.60.4-0.7-0.1-0.2-0.3-0.2-0.30.7-1.1-0.2-0.3-0.2
Bone: final moment0.10.21.10.40.4-0.6-0.0-0.1-0.2-0.1-0.20.6-1.0-0.1-0.2-0.2
Bone: marrow area0.00.10.10.20.3-0.2-0.3-0.3-0.3-0.3-0.20.1-0.2-0.3-0.3-0.2
Bone: maximum diameter0.20.40.70.70.7-0.6-0.7-0.7-0.6-0.6-0.60.6-0.8-0.6-0.7-0.6
Bone: maximum force0.10.21.20.50.5-0.7-0.2-0.2-0.3-0.1-0.30.6-1.1-0.2-0.3-0.3
Bone: maximum moment0.10.21.00.40.4-0.5-0.1-0.1-0.2-0.0-0.20.5-1.0-0.1-0.2-0.2
Bone: minimum diameter0.10.10.2-0.1-0.3-0.00.30.30.30.30.30.0-0.50.40.30.4
Bone: periosteal estimation0.20.40.60.70.7-0.7-0.7-0.6-0.6-0.5-0.50.6-0.8-0.5-0.7-0.6
Bone: periosteal perimeter0.00.10.20.20.4-0.2-0.2-0.3-0.3-0.2-0.20.1-0.2-0.3-0.4-0.3
Bone: post-yield work0.50.71.90.90.7-1.1-0.5-0.7-0.7-0.6-0.61.2-1.4-0.7-0.6-0.7
Bone: stiffness0.20.31.50.60.4-0.9-0.0-0.2-0.3-0.1-0.30.8-1.2-0.1-0.2-0.0
Bone: tissue strength0.20.20.3-0.4-0.30.30.60.50.50.50.4-0.30.10.50.50.4
Bone: trabecular number5.07.88.82.83.0-2.8-2.9-2.8-2.8-2.8-2.82.7-2.5-2.8-2.8-2.9
Bone: trabecular spacing2.33.04.5-1.6-2.01.52.11.71.71.81.8-1.41.31.81.81.8
Bone: trabecular thickness4.95.97.42.32.7-2.2-2.6-2.5-2.5-2.6-2.62.0-1.6-2.6-2.6-2.6
Bone: trabecular tissue density0.00.10.30.3-0.1-0.3-0.0-0.1-0.1-0.2-0.10.5-0.5-0.10.0-0.1
Breakpoint value in progressive ratio session0.50.50.80.70.1-0.4-0.5-0.9-0.9-0.9-0.90.40.1-0.8-0.9-0.9
Distance traveled before self-admin0.60.70.90.80.9-0.8-0.8-0.9-0.8-0.9-0.90.7-0.9-0.8-0.9-0.7
Distance traveled after self-admin4.85.36.52.51.7-2.5-2.1-2.4-2.4-2.4-2.42.6-2.2-2.3-2.3-2.2
Delta time in closed arm before/after self-admin0.10.10.5-0.2-0.20.2-0.70.10.10.00.0-0.1-0.4-0.00.20.1
Delta time in open arm before/after self-admin0.40.41.30.61.1-0.6-0.6-0.6-0.6-0.5-0.50.5-0.5-0.6-0.6-0.4
Diff in mean of infusions in LGA sessions0.80.91.30.80.8-0.6-1.0-1.0-1.1-1.1-1.10.5-0.2-1.1-1.1-1.1
Extinction: sum of active levers before priming2.12.23.41.51.2-1.3-1.2-1.7-1.7-1.7-1.71.0-0.2-1.5-1.9-1.7
Active lever presses in extinction session 61.21.24.2-1.0-1.01.21.40.60.60.70.7-1.42.00.80.61.0
Delta distance traveled before/after self-admin0.50.51.00.80.3-0.8-0.7-0.6-0.7-0.6-0.61.0-0.9-0.7-0.6-0.7
Delta ambulatory time before/after self-admin0.30.30.70.6-0.0-0.7-0.5-0.5-0.5-0.5-0.50.8-0.7-0.5-0.4-0.5
Time in closed arm before self-admin0.20.21.10.20.50.1-0.1-0.5-0.5-0.4-0.4-0.31.1-0.4-0.6-0.4
Time in closed arm after self-admin0.60.70.90.80.4-0.7-0.9-1.0-0.9-1.0-1.00.7-0.4-0.9-0.9-0.8
Time in open arm before self-admin0.70.81.3-0.8-1.10.80.90.80.90.90.9-0.70.30.91.01.0
Time in open arm after self-admin0.40.40.80.60.9-0.6-0.6-0.6-0.6-0.6-0.60.6-0.7-0.6-0.6-0.5
Sum of active levers in priming session hrs 5-60.20.20.9-0.10.10.5-0.3-0.3-0.4-0.4-0.4-0.60.9-0.3-0.4-0.3
Time to tail flick, vehicle, before self-admin0.00.00.20.20.5-0.2-0.1-0.2-0.2-0.2-0.20.00.0-0.2-0.3-0.1
Time to tail flick, vehicle, after self-admin0.10.10.7-0.00.80.10.1-0.0-0.0-0.0-0.0-0.20.0-0.1-0.1-0.2
Time to tail flick, test, before self-admin3.53.54.1-2.0-1.72.01.81.81.91.91.9-1.81.71.82.02.0
Time to tail flick, test, after self-admin1.31.42.0-1.2-1.01.01.41.21.21.11.1-1.21.21.31.11.2
Delta time to tail flick, vehicle, before/after SA0.10.10.1-0.30.10.30.30.30.30.30.3-0.2-0.00.20.30.0
Delta time to tail flick, test, before/after SA0.80.71.10.80.9-0.9-0.8-0.8-0.8-0.8-0.80.5-0.4-0.7-1.1-1.0
Ambulatory time before self-admin0.20.20.50.40.7-0.4-0.3-0.4-0.4-0.5-0.50.4-0.6-0.4-0.5-0.3
Ambulatory time after self-admin1.11.22.11.30.2-1.3-1.0-1.1-1.1-1.1-1.11.4-1.4-1.0-1.0-0.9
Total heroin consumption0.20.31.00.30.3-0.1-0.1-0.6-0.6-0.6-0.6-0.31.0-0.5-0.8-0.5
Area under the delay curve1.21.33.4-1.2-1.01.41.10.80.90.80.8-1.61.90.80.71.0
Delay disc. indifference point, 0s delay0.40.40.8-0.5-0.90.40.70.70.70.70.7-0.2-0.20.70.80.7
Delay disc. indifference point, 16s delay0.20.21.5-0.20.10.4-0.1-0.2-0.2-0.3-0.3-0.71.2-0.2-0.3-0.0
Delay disc. indifference point, 2s delay0.50.51.0-0.8-0.90.90.50.60.50.60.6-1.01.00.60.50.7
Delay disc. indifference point, 24s delay0.10.10.4-0.3-0.30.40.10.10.20.10.1-0.30.60.00.10.2
Delay disc. indifference point, 4s delay0.50.61.2-0.7-0.70.71.10.70.80.70.7-0.70.70.80.70.9
Delay disc. indifference point, 8s delay0.70.71.8-1.0-0.61.10.70.60.70.60.6-1.21.30.60.60.8
Delay discount exponential model param1.01.13.51.10.9-1.3-1.1-0.7-0.7-0.7-0.71.5-1.9-0.7-0.6-0.9
Delay discount hyperbolic model param1.51.53.51.41.1-1.5-1.3-1.0-1.0-0.9-0.91.7-1.9-1.0-0.9-1.1
Fecal boli incidents, locomotor time 12.02.22.6-1.5-1.31.41.51.51.61.61.6-1.51.31.51.41.3
Change in fecal boli incidents, locomotor task0.60.51.30.70.4-0.6-1.2-0.7-0.7-0.8-0.80.6-0.7-0.7-0.7-0.7
Time >=10cm from walls, locomotor time 14.64.66.1-2.2-1.42.01.92.52.42.52.5-1.90.82.22.42.4
Bouts of movement, locomotor time 18.99.911.6-3.2-2.93.13.03.33.23.13.1-3.43.43.12.92.9
Total resting periods, locomotor time 18.39.310.6-3.1-2.93.02.93.33.23.03.0-3.23.13.12.92.8
Rest time, locomotor task time 10.50.63.0-0.7-0.60.90.50.60.60.30.3-1.21.70.50.20.4
Distance moved, locomotor task time 10.20.20.4-0.4-0.60.50.40.30.30.50.5-0.2-0.20.40.60.6
Vertical activity count, locomotor time 10.70.82.00.90.9-0.9-0.7-0.8-0.9-0.7-0.71.2-1.4-0.8-0.6-0.6
Time >=10cm from walls, locomotor time 20.00.00.1-0.2-0.10.3-0.10.10.20.20.2-0.20.00.10.10.0
Bouts of movement, locomotor time 21.92.03.0-1.3-1.71.31.71.41.31.31.3-1.31.61.51.31.4
Total resting periods, locomotor time 21.51.62.7-1.2-1.61.11.51.21.21.11.1-1.21.41.31.21.3
Rest time, locomotor task time 20.10.10.30.10.1-0.0-0.5-0.1-0.0-0.3-0.3-0.00.3-0.2-0.2-0.3
Distance moved, locomotor task time 21.21.41.8-1.2-1.21.21.21.11.11.31.3-1.10.61.21.31.3
Vertical activity count, locomotor time 20.20.21.1-0.2-0.20.11.00.40.30.40.40.0-0.10.40.40.5
Weight adjusted by age0.30.40.9-0.2-0.7-0.10.10.80.70.60.60.3-0.90.60.80.5
Seeking ratio, delayed vs. immediate footshock1.41.62.11.41.2-1.3-0.7-1.5-1.3-1.3-1.31.2-0.5-1.3-1.4-1.5
Locomotion in novel chamber5.06.28.3-2.3-2.92.12.82.42.72.72.7-2.01.72.72.52.7
Locomotion in novel chamber post-restriction1.61.93.1-1.2-1.41.11.61.31.51.41.4-1.10.91.51.41.8
Progressive ratio2.73.15.2-1.8-1.62.02.11.61.61.51.5-2.02.31.61.51.6
Food seeking constrained by brief footshock0.30.41.1-0.5-1.10.50.50.40.40.50.5-0.50.90.50.60.6
Seeking ratio, punishment vs. effort1.11.32.11.20.6-1.3-1.5-1.1-1.1-1.0-1.01.3-1.3-1.1-1.0-1.0
Run reversals in cocaine runway, females0.50.51.0-0.5-0.90.31.00.80.80.80.8-0.20.20.80.80.9
Run reversals in cocaine runway, males0.10.10.8-0.1-0.90.20.60.1-0.00.00.0-0.20.60.20.1-0.1
Latency to leave start box in cocaine runway0.60.61.8-0.4-0.90.11.30.80.80.80.8-0.1-0.31.00.90.9
Latency to leave start box in cocaine runway, F0.30.32.10.60.2-0.8-0.2-0.1-0.1-0.1-0.11.0-1.4-0.1-0.0-0.0
Latency to leave start box in cocaine runway, M3.73.56.9-1.8-1.91.72.61.91.81.81.8-1.61.62.01.81.8
Cd content in liver0.40.40.70.70.6-0.7-0.6-0.6-0.5-0.8-0.80.7-0.8-0.6-0.6-0.6
Co content in liver0.20.20.40.50.5-0.40.2-0.5-0.5-0.6-0.60.40.1-0.6-0.5-0.6
Cu content in liver0.30.40.60.60.7-0.6-0.1-0.7-0.7-0.7-0.70.50.0-0.8-0.8-0.8
Fe content in liver4.45.25.72.42.2-2.3-2.3-2.3-2.3-2.4-2.42.2-1.7-2.4-2.4-2.4
K content in liver0.40.40.8-0.5-0.40.20.40.80.80.90.9-0.2-0.50.80.70.7
Mg content in liver0.10.10.70.10.2-0.3-0.10.10.20.30.30.3-0.80.20.10.1
Mn content in liver0.20.30.6-0.3-0.50.20.80.50.60.60.6-0.10.00.60.60.6
Na content in liver1.61.74.91.21.5-1.4-1.5-1.0-0.9-1.0-1.01.4-2.2-1.1-1.0-1.0
Rb content in liver2.32.94.4-1.5-1.91.42.11.61.61.81.8-1.41.71.81.61.6
Se content in liver0.00.00.1-0.1-0.30.10.20.20.20.30.3-0.20.10.20.10.2
Sr content in liver0.60.61.0-0.9-0.21.00.70.70.70.70.7-1.00.70.60.70.7
Zn content in liver0.00.00.0-0.1-0.20.20.20.20.10.00.0-0.10.10.10.20.1