Hub : Genes

Cep112

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024557 0.19 0.09 0.0e+00 0.12 0.15 0.14 0.14 2.3e-13 2.3e-16 5.1e-15 9.6e-16
2 Adipose isoform ratio ENSRNOT00000103396 0.06 0.04 3.0e-03 0.02 0.02 0.02 0.02 1.1e-03 4.8e-03 4.3e-03 3.7e-03
3 Adipose intron excision ratio chr10:93731914:93738578 0.06 0.04 5.9e-05 0.04 0.02 0.02 0.03 4.2e-05 1.8e-03 2.4e-03 5.3e-04
4 Brain alternative TSS ENSRNOT00000037067 0.07 0.04 4.4e-06 0.05 0.04 0.05 0.05 2.8e-05 1.9e-04 2.2e-05 8.9e-06
5 Brain gene expression ENSRNOG00000024557 0.11 0.06 3.2e-09 0.09 0.02 0.1 0.03 4.9e-09 3.3e-03 1.3e-09 3.5e-04
6 LHb gene expression ENSRNOG00000024557 0.35 0.15 2.2e-05 0.25 0.08 0.13 0.16 1.5e-06 6.5e-03 4.9e-04 1.3e-04
7 Liver gene expression ENSRNOG00000024557 0.04 0.03 1.6e-04 0.02 0.02 0.01 0.02 3.5e-03 1.3e-03 4.2e-02 2.6e-03
8 Liver isoform ratio ENSRNOT00000037067 0.03 0.02 4.9e-03 0.02 0.01 0.01 0.01 2.3e-03 1.8e-02 2.8e-02 1.1e-02
9 NAcc alternative TSS ENSRNOT00000108519 0.12 0.06 2.9e-08 0.11 0.1 0.09 0.1 1.2e-08 3.2e-08 4.1e-07 3.3e-08
10 NAcc gene expression ENSRNOG00000024557 0.06 0.04 4.2e-04 0.07 0.04 0.04 0.05 1.1e-05 4.0e-04 3.3e-04 7.1e-05
11 NAcc isoform ratio ENSRNOT00000108519 0.14 0.06 3.3e-09 0.1 0.12 0.11 0.12 3.0e-08 2.5e-09 2.0e-08 6.8e-09
12 NAcc intron excision ratio chr10:93381939:93423087 0.07 0.05 3.6e-03 0.01 0.01 0.02 0.01 5.8e-02 1.1e-01 7.1e-03 4.1e-02
13 PL gene expression ENSRNOG00000024557 0.14 0.07 2.5e-08 0.1 0.1 0.08 0.09 2.4e-08 7.2e-08 8.7e-07 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail6.721.731.21.24.45.63.9-5.0-5.61.05.6-5.6-5.5-5.52.2-5.5
BMI without tail4.79.920.21.74.53.52.1-3.3-3.31.73.6-3.5-3.5-3.12.2-3.5
Body weight5.422.739.53.74.35.62.9-6.3-5.53.55.4-5.6-5.4-4.70.5-5.4
Epididymis fat weight6.314.723.51.82.64.63.6-4.8-4.61.64.5-4.5-4.4-4.51.3-4.4
Glucose0.20.31.7-0.8-1.30.3-0.1-0.0-0.4-0.80.1-0.3-0.2-0.5-0.7-0.2
Heart weight1.52.15.31.50.01.4-0.2-2.3-1.51.41.3-1.5-1.4-1.2-2.0-1.4
Left kidney weight1.13.15.80.51.52.01.0-2.4-2.30.42.0-2.0-2.0-2.3-0.5-2.0
Right kidney weight1.43.99.01.51.42.30.6-3.0-2.51.42.0-2.2-2.2-2.1-1.0-2.2
Tail length0.41.35.92.41.40.4-0.5-1.2-0.12.40.4-0.4-0.40.4-0.4-0.4
Length with tail0.83.19.83.10.61.3-0.3-2.7-1.33.11.1-1.3-1.2-0.4-2.1-1.2
Length without tail0.51.02.50.9-0.90.90.6-1.6-1.30.80.6-0.9-0.9-0.9-1.5-0.9
Liver weight, left0.81.32.3-0.6-0.8-1.3-0.31.51.3-0.5-1.51.31.51.30.41.5
Liver weight, right0.40.61.4-1.20.1-0.50.91.00.4-1.1-0.70.50.70.11.10.7
Parametrial fat weight1.42.85.1-0.1-0.3-2.1-1.41.72.0-0.0-2.32.12.11.90.62.1
Retroperitoneal fat weight4.916.326.82.83.84.72.6-5.2-5.02.74.6-4.7-4.6-4.11.0-4.6
Intraocular pressure0.40.50.90.20.40.80.5-0.9-0.80.20.9-0.8-0.9-0.80.1-0.9
Extensor digitorum longus weight2.39.316.0-0.8-0.13.53.7-2.8-3.7-1.03.7-3.5-3.7-4.01.7-3.7
Soleus weight0.61.73.20.7-0.21.5-0.2-1.8-1.50.61.6-1.4-1.6-1.3-1.3-1.6
Tibialis anterior weight1.96.710.40.91.83.22.3-2.9-3.20.83.1-3.1-3.1-2.91.3-3.1
Tibia length0.61.83.91.40.11.40.4-2.0-1.41.41.5-1.4-1.4-1.1-1.7-1.4
Number of licking bursts0.20.31.30.70.00.1-0.8-0.6-0.20.70.3-0.1-0.30.0-1.2-0.3
Food consumed during 24 hour testing period2.83.48.40.42.91.92.0-1.2-2.00.41.7-1.9-1.7-1.72.7-1.7
Times rat made contact with spout0.50.61.01.00.70.90.4-1.0-0.91.00.7-0.9-0.7-0.3-0.2-0.7
Mean time between licks in bursts2.02.84.71.30.02.10.5-2.2-2.11.22.0-2.1-2.0-1.8-0.6-2.0
Mean num. licks in bursts0.20.21.1-0.20.40.51.00.0-0.3-0.20.2-0.5-0.2-0.40.9-0.2
Std. dev. time between licks in bursts1.01.23.2-0.60.81.21.3-0.3-1.0-0.71.1-1.2-1.1-1.41.8-1.1
Water consumed over 24 hours1.51.84.5-0.32.01.41.7-0.6-1.4-0.31.2-1.4-1.2-1.42.1-1.2
Indifference point 0 sec2.74.312.03.43.41.4-0.7-2.5-1.73.51.5-1.4-1.5-0.5-0.6-1.5
Indifference point AUC0.30.31.10.91.00.3-0.7-0.5-0.10.90.4-0.3-0.30.1-0.3-0.3
Indifference point function ln k0.71.01.7-1.2-0.3-1.3-0.31.30.9-1.1-1.21.21.10.60.31.1
Indifference point function log k0.71.01.7-1.2-0.3-1.3-0.31.30.9-1.1-1.21.21.10.60.31.1
Delay discounting total patch changes 0 sec2.43.911.23.33.31.3-0.5-2.3-1.63.41.4-1.3-1.3-0.4-0.5-1.3
Delay discounting total patch changes 12 sec1.82.49.33.02.30.8-1.0-1.6-0.83.10.7-0.8-0.50.3-0.8-0.5
Delay discounting total patch changes 18 sec1.92.64.51.92.11.80.2-2.0-1.71.91.7-1.7-1.5-1.1-0.0-1.5
Delay discounting total patch changes 24 sec2.22.86.72.62.11.3-0.7-2.2-1.42.61.5-1.3-1.4-0.6-1.0-1.4
Delay discounting total patch changes 6 sec3.65.413.83.73.01.8-0.9-3.1-1.93.72.1-1.8-1.9-0.7-1.4-1.9
Delay discounting time to switch 0 sec0.10.20.5-0.0-0.40.70.6-0.4-0.4-0.10.5-0.6-0.3-0.6-0.1-0.3
Delay discounting water rate 0 sec0.40.72.81.41.7-0.1-0.8-0.7-0.31.5-0.00.0-0.10.3-0.3-0.1
Delay discounting water rate 12 sec0.30.40.8-0.00.10.50.9-0.8-0.9-0.00.8-0.6-0.9-0.80.0-0.9
Delay discounting water rate 18 sec0.20.20.8-0.50.70.10.70.1-0.4-0.50.1-0.2-0.2-0.50.9-0.2
Delay discounting water rate 24 sec0.40.61.4-1.2-0.9-0.8-0.31.00.6-1.1-0.80.70.60.30.10.6
Delay discounting water rate 6 sec0.30.41.2-1.10.6-0.30.40.60.1-1.0-0.60.20.5-0.30.80.5
Locomotor activity1.82.96.41.52.52.00.3-1.9-2.01.51.8-2.0-1.7-1.20.4-1.7
Locomotor testing distance1.32.14.51.12.11.70.2-1.5-1.91.11.6-1.9-1.4-1.10.4-1.4
Locomotor testing rearing1.82.95.10.82.32.11.0-1.7-2.00.82.0-2.1-2.0-1.41.2-2.0
Light reinforcement 11.22.27.7-0.92.81.21.9-0.3-1.0-0.91.1-1.2-1.0-1.72.4-1.0
Light reinforcement 20.10.20.7-0.60.30.30.5-0.1-0.3-0.60.1-0.20.0-0.8-0.20.0
Reaction time number correct0.91.32.1-1.1-1.3-1.4-0.41.41.2-1.1-1.31.41.10.8-0.11.1
Reaction time mean minus median0.00.00.20.1-0.40.00.1-0.0-0.10.1-0.2-0.00.1-0.00.40.1
Reaction time mean minus median AUC0.81.01.9-0.1-0.8-1.2-0.91.11.0-0.1-1.41.21.21.1-0.01.2
Reaction time num false alarms1.31.83.11.71.31.4-1.0-1.6-0.91.81.5-1.4-1.4-0.4-0.9-1.4
Reaction time num false alarms AUC1.21.74.32.01.51.1-1.3-1.4-0.72.11.2-1.1-1.10.1-0.9-1.1
Reaction time trials correct on left0.91.32.1-1.1-1.3-1.4-0.41.41.2-1.1-1.31.41.10.8-0.11.1
Reaction time trials on left0.91.32.2-1.0-1.2-1.4-0.51.41.2-1.0-1.31.51.10.9-0.11.1
Reaction time mean1.21.63.2-0.2-0.6-1.5-1.01.31.5-0.2-1.81.51.61.4-0.31.6
Reaction time mean AUC0.91.32.7-0.3-0.4-1.4-0.71.31.4-0.3-1.61.31.41.3-0.01.4
Median of all reaction times1.52.03.8-0.2-0.4-1.7-1.31.51.7-0.2-2.01.71.81.6-0.51.8
Reaction time omissions0.20.20.60.80.7-0.3-0.4-0.10.10.8-0.50.30.40.3-0.20.4
Reaction time false alarm rate1.82.54.62.11.71.7-0.8-2.0-1.22.11.8-1.8-1.6-0.5-0.7-1.6
Reaction time premature initiation rate1.72.24.11.61.91.6-0.5-2.0-1.71.51.5-1.7-1.3-1.3-1.1-1.3
Reaction time premature initiations0.30.41.00.71.00.4-0.9-0.8-0.60.70.4-0.4-0.3-0.4-1.0-0.3
Std. dev. reaction times0.50.71.40.2-0.8-1.0-0.60.71.00.2-1.21.01.11.1-0.11.1
Reaction time trials completed0.91.32.2-1.0-1.2-1.4-0.51.41.2-1.0-1.31.51.10.9-0.11.1
Reaction time trials AUC0.91.32.3-1.1-1.2-1.5-0.41.41.2-1.1-1.41.51.20.90.01.2
Social response proportion0.30.41.20.80.9-0.2-1.1-0.20.10.8-0.30.30.30.3-0.90.3
Social responses1.82.37.42.02.71.4-0.5-1.6-1.32.01.5-1.4-1.4-0.6-0.1-1.4
Social time0.20.21.50.5-0.50.0-0.8-0.30.10.4-0.20.00.30.3-1.20.3
Conditioned locomotion0.10.20.3-0.20.2-0.5-0.50.50.5-0.2-0.40.50.40.40.30.4
Cocaine response after cond. corrected0.40.42.80.4-0.5-0.3-1.1-0.20.30.3-0.40.30.40.2-1.70.4
Cocaine response after cond. not corrected0.60.74.80.3-1.0-0.4-1.4-0.20.40.2-0.50.30.50.4-2.20.5
Cocaine response before conditioning0.20.30.9-0.4-1.0-0.4-0.70.40.5-0.4-0.50.40.50.5-0.70.5
Saline control response3.54.77.00.62.62.61.8-2.1-2.70.62.4-2.7-2.4-2.31.5-2.4
Condit. Reinf. active minus inactive responses2.12.67.82.60.6-0.6-2.8-0.50.82.6-0.50.50.51.7-2.60.5
Condit. Reinf. active-inactive response ratio1.92.06.02.20.1-0.6-2.4-0.50.72.3-0.40.50.41.5-2.50.4
Condit. Reinf. active responses2.02.88.52.81.2-0.4-2.9-0.60.62.9-0.50.30.51.6-2.40.5
Condit. Reinf. inactive responses0.30.42.20.81.5-0.1-1.00.10.10.9-0.40.10.40.50.10.4
Condit. Reinf. lever presses1.52.06.52.52.30.7-1.3-1.4-0.62.50.9-0.7-0.90.3-1.0-0.9
Condit. Reinf. lever reinforcers received1.92.68.72.91.2-0.3-2.7-0.80.42.9-0.40.20.41.5-2.20.4
Pavlov. Cond. lever latency0.60.82.7-0.9-0.30.71.6-0.4-0.7-1.00.8-0.7-0.7-1.21.2-0.7
Pavlov. Cond. magazine entry latency0.20.20.7-0.6-0.80.0-0.20.3-0.3-0.6-0.0-0.10.0-0.3-0.80.0
Pavlov. Cond. change in total contacts0.30.41.50.6-0.1-0.4-1.20.30.40.7-0.60.40.50.8-1.10.5
Pavlov. Cond. index score0.30.42.00.8-0.1-0.1-1.2-0.1-0.00.8-0.10.10.10.5-1.40.1
Pavlov. Cond. latency score0.40.52.30.7-0.3-0.3-1.30.10.10.7-0.30.20.30.6-1.50.3
Pavlov. Cond. lever contacts0.20.30.90.81.0-0.3-1.00.20.20.9-0.30.30.30.7-0.40.3
Pavlov. Cond. magazine entry number0.30.30.80.70.9-0.4-0.20.10.70.8-0.30.50.30.70.80.3
Pavlov. Cond. intertrial magazine entries0.81.14.21.72.1-0.2-1.1-0.20.51.8-0.20.30.21.00.80.2
Pavlov. Cond. lever-magazine prob. diff.0.30.42.20.7-0.3-0.2-1.30.10.10.7-0.30.20.30.5-1.50.3
Pavlov. Cond. response bias0.20.31.10.70.5-0.3-1.00.30.20.7-0.30.30.30.6-0.70.3
Conditioned reinforcement - actives1.91.93.3-0.5-0.0-1.8-0.91.61.8-0.4-1.61.81.61.70.81.6
Conditioned reinforcement - inactives0.50.61.61.20.30.5-0.4-1.0-0.51.20.6-0.5-0.6-0.0-1.2-0.6
Conditioned locomotion0.81.03.31.80.8-0.2-1.6-0.60.31.8-0.10.20.10.9-1.20.1
Intermittent access intake day 1-15 change1.11.13.01.70.40.7-1.2-1.4-0.61.70.5-0.7-0.50.0-1.4-0.5
Intermittent access intake escalation1.11.02.71.60.20.8-1.0-1.5-0.71.60.6-0.8-0.6-0.1-1.5-0.6
Intermittent access intake escalation 21.71.65.42.30.70.7-1.6-1.6-0.62.30.6-0.7-0.50.3-1.7-0.5
Intermitt. access day 1 inactive lever presses1.71.83.11.71.11.3-0.4-1.8-1.31.71.2-1.3-1.5-0.6-1.4-1.5
Intermitt. access day 15 inactive lever presses1.51.63.61.11.11.50.7-1.9-1.61.01.4-1.5-1.3-1.3-0.2-1.3
Intermitt. access escalation Index1.31.11.9-0.8-1.0-1.3-0.21.41.3-0.7-1.21.31.21.10.31.2
Intermittent access day 1 total infusions0.10.10.60.40.8-0.0-0.10.00.10.50.10.00.00.20.40.0
Intermittent access day 15 total infusions1.21.44.62.11.10.8-1.1-1.5-0.72.10.7-0.8-0.50.1-1.1-0.5
Intermittent access terminal intake (last 3 days)1.51.66.42.51.40.5-1.5-1.4-0.42.50.6-0.5-0.40.5-1.0-0.4
Intermittent access total infusions0.91.04.02.01.40.4-0.9-1.0-0.32.00.4-0.4-0.20.4-0.6-0.2
Intermittent access day 1 locomotion2.12.14.32.01.31.4-0.4-1.9-1.22.11.5-1.4-1.5-0.6-0.9-1.5
Intermittent access day 15 total locomotion2.12.37.62.71.80.8-1.4-1.7-0.72.81.0-0.8-1.00.2-1.3-1.0
Intermittent access total locomotion4.14.712.73.52.41.7-0.9-2.8-1.63.61.8-1.7-1.9-0.5-1.5-1.9
Intermittent access standard deviation2.22.44.62.10.31.5-1.3-1.9-1.22.11.4-1.5-1.4-0.5-2.1-1.4
Cocaine induced anxiety0.60.71.5-0.6-0.6-0.8-0.21.10.8-0.6-1.10.81.20.70.41.2
Post-drug Anxiety1.01.12.9-1.1-1.7-0.9-0.01.30.9-1.2-1.30.91.20.5-0.01.2
Baseline Anxiety0.60.72.6-1.6-0.6-0.21.00.80.2-1.6-0.30.20.1-0.50.90.1
Lifetime Intake0.80.93.71.71.90.4-0.7-1.0-0.31.80.5-0.4-0.30.2-0.3-0.3
Incentive Sensitization - Responses1.31.32.20.1-0.8-1.3-1.41.01.30.1-1.31.31.21.5-0.91.2
Incentive Sensitization - Breakpoint1.51.52.50.0-1.0-1.5-1.41.11.40.1-1.51.41.41.6-0.91.4
Progressive ratio test 1 active lever presses2.12.26.31.52.51.50.8-1.4-1.31.61.6-1.5-1.5-0.71.0-1.5
Progressive ratio test 1 breakpoint2.42.47.51.62.71.50.7-1.5-1.41.81.7-1.5-1.6-0.80.9-1.6
Progressive ratio test 1 inactive lever presses2.42.66.31.92.51.50.4-2.2-1.52.01.5-1.5-1.6-0.9-0.5-1.6
Progressive ratio test 2 active lever presses0.40.41.81.31.0-0.0-0.8-0.30.21.3-0.00.00.10.6-0.40.1
Progressive ratio test 2 breakpoint0.50.52.01.31.1-0.2-0.8-0.20.31.4-0.20.20.20.8-0.30.2
Progressive ratio test 2 inactive lever presses0.70.92.91.60.8-0.3-1.4-0.30.31.7-0.20.30.30.9-1.20.3
Total sessions with >9 infusions0.10.10.70.10.80.20.0-0.3-0.10.20.3-0.2-0.2-0.30.2-0.2
Short access day 1 total inactive lever presses0.10.10.30.20.10.10.3-0.4-0.10.2-0.1-0.10.4-0.2-0.60.4
Short access day 10 total inactive lever presses0.70.81.71.20.60.6-0.5-1.3-0.71.20.6-0.6-1.0-0.4-1.3-1.0
Short access day 1 total infusions0.20.21.1-0.31.10.10.7-0.1-0.0-0.20.4-0.1-0.3-0.40.6-0.3
Short access day 10 total infusions3.03.310.62.23.31.70.4-2.0-1.62.21.8-1.7-1.6-0.90.6-1.6
Short access total infusions0.70.84.91.22.20.4-0.2-0.8-0.31.30.6-0.4-0.6-0.00.3-0.6
Short access day 1 locomotion1.41.56.20.92.51.20.8-1.1-0.90.91.1-1.2-0.9-1.01.4-0.9
Short access day 10 total locomotion4.04.49.83.11.81.9-0.4-2.9-1.73.11.9-1.9-2.1-0.9-1.4-2.1
Short access total locomotion4.04.18.42.22.92.10.7-2.6-1.92.32.1-2.1-2.1-1.50.4-2.1
Compulsive drug intake1.41.34.60.9-0.9-1.0-2.10.20.90.8-0.91.00.61.2-2.10.6
One hour access (0.3 mA shock)1.21.45.31.81.0-0.5-2.3-0.40.51.9-0.30.50.31.2-1.60.3
One hour access (shock baseline)0.40.41.80.91.30.5-0.2-0.7-0.41.00.6-0.5-0.5-0.10.1-0.5
Number of responses in last shaping day1.01.01.90.40.81.41.0-1.3-1.20.41.1-1.4-1.0-1.20.4-1.0
Context. condit. distance diff. score0.10.20.50.20.30.40.0-0.7-0.60.10.4-0.4-0.3-0.7-0.4-0.3
Locomotion velocity, session 10.00.00.40.1-0.3-0.10.2-0.0-0.60.10.00.2-0.00.1-0.0-0.0
Locomotion distance, session 10.10.10.6-0.2-0.20.20.6-0.2-0.8-0.20.4-0.3-0.4-0.40.3-0.4
Locomotion velocity, session 20.40.50.9-0.50.2-0.8-0.11.00.4-0.4-0.70.80.80.90.80.8
Locomotion distance, session 20.20.31.4-0.80.3-0.10.60.6-0.3-0.80.10.1-0.00.01.2-0.0
Locomotion velocity, session 30.70.92.7-1.6-0.30.71.30.1-0.7-1.60.5-0.7-0.4-1.20.8-0.4
Locomotion distance, session 30.30.31.4-0.3-1.0-0.2-0.70.20.3-0.3-0.30.20.40.2-1.20.4
Stereotopy head waving bouts, day 32.73.37.7-2.8-1.0-1.70.72.51.4-2.7-1.71.61.70.61.81.7
Stereotopy head waving duration, day 31.41.74.3-2.1-1.1-1.30.31.81.0-2.1-1.21.31.20.40.81.2
Locomotion velocity, session 70.20.20.7-0.8-0.40.40.50.0-0.4-0.80.3-0.3-0.3-0.50.6-0.3
Locomotion distance, session 70.20.31.00.7-0.10.2-0.9-0.5-0.00.70.2-0.2-0.20.0-1.0-0.2
Stereotopy head waving bouts, day 71.01.24.7-2.2-0.6-0.31.21.20.4-2.2-0.60.30.6-0.31.20.6
Stereotopy head waving duration, day 72.22.78.2-2.9-1.4-1.21.12.21.2-2.8-1.31.11.30.31.21.3
Locomotion velocity, session 80.10.20.50.0-0.7-0.6-0.60.20.20.1-0.30.40.40.5-0.30.4
Locomotion distance, session 80.00.10.3-0.10.5-0.00.1-0.1-0.4-0.10.1-0.1-0.0-0.10.4-0.0
Degree of sensitization distance0.10.10.50.70.7-0.1-0.3-0.20.10.70.10.1-0.10.20.2-0.1
Degree of sensitization stereotypy0.60.72.6-1.6-0.20.41.30.4-0.3-1.60.1-0.4-0.2-0.70.8-0.2
Condit. Reinf. active minus inactive responses1.51.75.82.40.70.4-1.5-1.4-0.32.40.4-0.3-0.40.5-2.1-0.4
Condit. Reinf. active-inactive response ratio0.70.72.31.3-0.3-0.5-1.2-0.30.61.2-0.40.50.50.9-1.50.5
Condit. Reinf. active responses1.31.55.32.31.20.4-1.4-1.3-0.32.30.5-0.3-0.50.5-1.8-0.5
Condit. Reinf. inactive responses0.30.31.10.81.10.4-0.4-0.5-0.40.80.4-0.4-0.4-0.0-0.2-0.4
Incentive salience index mean0.80.92.91.71.00.5-0.9-1.1-0.41.70.7-0.4-0.60.2-1.1-0.6
Condit. Reinf. lever presses0.81.02.00.11.01.10.8-0.9-1.00.11.4-1.1-1.4-1.00.5-1.4
Time in familiar zone, hab. session 10.90.82.81.70.1-0.1-1.5-0.80.41.70.40.1-0.40.6-1.2-0.4
Time in novel zone, hab. session 10.50.51.5-1.20.30.21.20.6-0.4-1.2-0.1-0.20.1-0.51.20.1
Total zone transitions, hab. session 11.82.54.50.21.21.81.7-1.5-2.10.22.0-1.7-1.9-1.61.2-1.9
Total locomotion distance, hab. session 11.11.63.20.21.81.31.4-0.8-1.50.21.4-1.2-1.4-1.01.7-1.4
Locomotion velocity, hab. session 11.01.42.70.11.51.21.6-0.7-1.40.11.3-1.1-1.2-1.01.6-1.2
Time in familiar zone, hab. session 20.60.62.11.40.40.2-1.1-0.80.11.40.3-0.2-0.30.4-1.2-0.3
Time in novel zone, hab. session 21.31.42.8-1.6-0.6-1.10.81.70.7-1.5-1.21.11.10.51.51.1
Total zone transitions, hab. session 22.43.15.5-0.31.11.92.1-1.4-2.3-0.42.1-1.9-2.0-2.01.7-2.0
Total locomotion distance, hab. session 22.02.66.3-0.31.91.52.2-0.9-1.7-0.31.7-1.6-1.6-1.62.5-1.6
Locomotion velocity, hab. session 21.72.26.6-0.61.61.32.2-0.6-1.5-0.61.5-1.3-1.4-1.52.6-1.4
Novel to familiar place preference ratio1.11.13.92.00.40.3-1.2-1.1-0.32.00.3-0.3-0.40.3-1.7-0.4
Novelty place preference0.70.72.51.60.20.3-0.9-1.0-0.41.60.3-0.3-0.40.1-1.4-0.4
Time in novel zone, NPP test0.60.62.11.40.30.2-0.9-0.9-0.41.50.2-0.3-0.30.2-1.3-0.3
Total zone transitions, NPP test0.91.23.5-0.91.00.71.5-0.3-1.5-0.81.0-0.7-0.9-1.21.9-0.9
Total locomotion distance, NPP test0.91.27.1-0.52.00.31.60.3-0.9-0.50.5-0.3-0.4-0.42.7-0.4
Locomotion velocity, NPP test1.11.56.0-0.51.80.71.9-0.2-1.4-0.50.9-0.7-0.9-1.02.5-0.9
Pavlov. Cond. lever latency2.22.74.4-1.1-1.7-2.0-0.71.92.1-1.0-2.11.82.11.4-0.12.1
Pavlov. Cond. magazine entry latency0.91.23.41.81.50.9-0.6-1.3-0.71.80.8-0.8-0.8-0.1-0.9-0.8
Pavlov. Cond. change in total contacts2.12.23.71.51.91.60.2-1.7-1.61.61.7-1.5-1.7-0.9-0.4-1.7
Pavlov. Cond. index score1.41.82.91.61.71.4-0.2-1.6-1.31.61.4-1.3-1.4-0.7-0.7-1.4
Pavlov. Cond. latency score1.82.33.41.51.71.70.1-1.9-1.71.51.8-1.6-1.8-1.1-0.7-1.8
Pavlov. Cond. lever contacts3.13.76.10.91.62.31.1-2.1-2.40.82.5-2.2-2.5-1.80.2-2.5
Pavlov. Cond. magazine entry number0.50.62.2-1.4-1.0-0.40.70.70.3-1.5-0.40.30.4-0.20.90.4
Pavlov. Cond. intertrial magazine entries1.21.44.32.10.50.7-1.1-1.5-0.72.10.7-0.7-0.7-0.1-1.8-0.7
Pavlov. Cond. lever-magazine prob. diff.1.31.62.81.41.71.4-0.2-1.5-1.31.41.4-1.3-1.4-0.7-0.6-1.4
Pavlov. Cond. response bias0.80.91.71.31.30.9-0.1-1.1-0.91.31.0-0.9-1.0-0.3-0.4-1.0
Bone: apparent density0.50.92.40.2-0.4-1.1-1.60.81.10.3-1.01.11.01.2-0.31.0
Bone surface1.73.010.01.9-0.5-1.5-3.20.41.62.0-1.41.51.42.4-1.81.4
Bone volume1.22.08.11.9-0.4-0.9-2.9-0.10.92.0-0.80.90.81.7-1.90.8
Bone: connectivity density1.82.84.6-0.5-0.3-2.1-1.62.12.2-0.4-1.92.01.92.10.71.9
Bone: cortical apparent density1.21.55.0-2.21.1-0.01.71.0-0.2-2.20.1-0.0-0.2-1.31.9-0.2
Bone: cortical area1.01.55.11.52.31.0-0.7-1.3-1.11.61.1-1.0-1.1-0.5-0.3-1.1
Bone: cortical porosity1.01.13.91.90.40.1-1.6-0.9-0.02.00.2-0.1-0.21.0-1.3-0.2
Bone: cortical porosity1.41.54.42.10.60.8-1.3-1.5-0.82.10.8-0.8-0.80.2-1.6-0.8
Bone: cortical thickness3.76.211.5-2.03.02.23.1-0.8-2.5-2.12.4-2.3-2.4-3.42.9-2.4
Bone: cortical thickness1.31.55.4-1.52.00.51.50.5-0.8-1.50.5-0.4-0.6-1.22.3-0.6
Bone: cortical tissue density1.21.54.8-2.11.00.01.71.0-0.2-2.20.1-0.1-0.2-1.31.9-0.2
Bone: elastic displacement0.40.51.9-1.3-0.1-0.01.00.60.0-1.40.0-0.00.0-0.41.00.0
Bone: elastic work0.70.91.4-0.11.21.01.1-0.6-1.1-0.11.0-1.0-1.0-1.01.1-1.0
Bone: endosteal estimation5.712.240.76.20.1-1.0-5.5-2.01.26.4-1.01.11.03.7-5.01.0
Bone: endosteal perimeter5.611.435.95.9-0.4-0.8-5.5-2.01.06.0-0.90.90.93.2-5.30.9
Bone: final force0.50.82.51.51.4-0.1-1.5-0.40.01.60.10.2-0.10.6-0.7-0.1
Bone: final moment0.50.82.61.51.3-0.3-1.6-0.30.21.6-0.10.40.10.7-0.70.1
Bone: marrow area5.611.939.36.10.1-1.0-5.5-1.91.26.3-1.01.11.03.7-5.01.0
Bone: maximum diameter2.34.112.53.0-0.2-1.2-3.5-0.41.23.1-1.11.11.12.3-3.01.1
Bone: maximum force0.91.55.22.21.50.3-1.9-1.1-0.22.30.5-0.2-0.50.4-1.3-0.5
Bone: maximum moment0.91.55.32.21.50.2-1.9-1.0-0.12.30.3-0.1-0.30.6-1.3-0.3
Bone: minimum diameter4.07.429.15.31.50.3-3.8-2.4-0.45.40.4-0.2-0.41.6-3.6-0.4
Bone: periosteal estimation3.77.527.65.11.4-0.3-4.3-1.90.45.3-0.30.40.32.4-3.70.3
Bone: periosteal perimeter2.64.414.13.60.10.2-3.4-1.9-0.23.60.3-0.2-0.31.1-3.8-0.3
Bone: post-yield work1.11.54.82.20.30.6-1.5-1.5-0.22.20.8-0.5-0.80.2-1.7-0.8
Bone: stiffness0.61.03.21.71.30.2-1.6-0.80.11.80.3-0.1-0.30.4-1.0-0.3
Bone: tissue strength0.90.92.8-1.7-0.9-0.70.31.30.9-1.6-0.70.80.70.20.70.7
Bone: trabecular number1.52.33.6-0.2-0.5-1.9-1.81.71.9-0.1-1.81.91.81.9-0.11.8
Bone: trabecular spacing0.60.81.6-0.00.41.11.2-0.8-1.3-0.11.1-1.1-1.1-1.10.3-1.1
Bone: trabecular thickness0.40.51.81.20.4-0.3-1.4-0.30.31.3-0.30.30.30.6-0.90.3
Bone: trabecular tissue density0.10.10.6-0.30.60.20.3-0.2-0.3-0.30.2-0.3-0.3-0.8-0.0-0.3
Breakpoint value in progressive ratio session0.91.02.5-1.10.10.91.6-0.4-1.2-1.10.7-1.0-0.6-1.41.1-0.6
Distance traveled before self-admin0.90.92.5-1.0-1.6-0.9-0.00.91.0-1.0-1.10.91.10.6-0.41.1
Distance traveled after self-admin0.20.20.9-0.6-1.0-0.20.20.30.2-0.7-0.40.20.50.1-0.10.5
Delta time in closed arm before/after self-admin1.11.12.6-0.1-1.6-1.1-1.10.81.1-0.1-1.41.11.01.1-1.01.0
Delta time in open arm before/after self-admin1.31.22.1-1.4-1.0-1.00.31.41.0-1.4-1.01.01.30.51.01.3
Diff in mean of infusions in LGA sessions1.71.93.9-0.60.31.51.7-1.2-1.6-0.71.6-1.5-1.4-2.01.1-1.4
Extinction: sum of active levers before priming0.20.20.4-0.30.30.60.3-0.4-0.6-0.30.5-0.6-0.4-0.70.5-0.4
Active lever presses in extinction session 60.40.30.80.50.80.50.6-0.7-0.70.50.5-0.4-0.3-0.40.9-0.3
Delta distance traveled before/after self-admin0.50.52.3-0.70.90.50.80.1-0.6-0.70.6-0.6-0.4-0.61.5-0.4
Delta ambulatory time before/after self-admin0.10.10.70.10.5-0.0-0.30.2-0.10.20.0-0.10.10.30.80.1
Time in closed arm before self-admin0.91.05.10.02.31.10.7-0.2-0.70.10.9-1.0-0.9-0.61.4-0.9
Time in closed arm after self-admin0.10.10.30.40.40.5-0.0-0.2-0.40.50.2-0.5-0.50.10.1-0.5
Time in open arm before self-admin1.81.94.30.6-0.91.31.0-2.1-1.60.41.6-1.4-1.6-1.6-1.4-1.6
Time in open arm after self-admin0.30.32.0-0.3-1.4-0.00.5-0.7-0.3-0.40.2-0.00.1-0.7-0.70.1
Sum of active levers in priming session hrs 5-60.20.20.50.20.20.60.2-0.7-0.70.20.5-0.6-0.3-0.5-0.1-0.3
Time to tail flick, vehicle, before self-admin0.90.94.60.3-2.2-0.7-0.50.10.60.2-0.90.71.00.8-1.31.0
Time to tail flick, vehicle, after self-admin1.31.44.00.7-1.6-0.8-2.00.91.10.7-1.10.91.11.4-1.21.1
Time to tail flick, test, before self-admin0.80.82.01.2-1.2-0.5-1.0-0.40.41.2-0.70.50.80.9-1.40.8
Time to tail flick, test, after self-admin0.91.02.51.40.2-0.6-1.60.00.91.4-0.70.70.71.3-1.20.7
Delta time to tail flick, vehicle, before/after SA1.51.43.20.60.4-1.1-1.81.41.40.8-1.31.21.21.70.21.2
Delta time to tail flick, test, before/after SA0.90.82.90.4-0.1-0.8-1.70.71.20.5-0.70.90.61.2-1.10.6
Ambulatory time before self-admin0.60.61.5-1.0-1.2-0.70.40.80.7-1.1-0.90.70.80.2-0.40.8
Ambulatory time after self-admin0.20.20.5-0.7-0.6-0.20.30.50.1-0.7-0.30.10.40.10.60.4
Total heroin consumption0.10.10.30.4-0.1-0.2-0.6-0.10.20.4-0.30.20.30.4-0.50.3
Area under the delay curve0.10.10.4-0.0-0.60.1-0.5-0.10.0-0.1-0.3-0.00.7-0.2-0.40.7
Delay disc. indifference point, 0s delay0.20.20.9-0.5-1.0-0.1-0.00.10.1-0.5-0.30.10.7-0.2-0.40.7
Delay disc. indifference point, 16s delay0.10.10.30.20.40.60.2-0.6-0.40.20.4-0.4-0.0-0.60.1-0.0
Delay disc. indifference point, 2s delay1.01.12.80.0-0.9-1.0-1.10.91.10.1-1.31.11.71.0-0.31.7
Delay disc. indifference point, 24s delay0.90.91.81.20.91.1-0.4-1.3-1.01.11.0-1.0-0.6-0.8-0.4-0.6
Delay disc. indifference point, 4s delay0.50.51.2-0.7-1.1-0.6-0.60.60.6-0.7-0.90.51.00.3-0.31.0
Delay disc. indifference point, 8s delay0.20.30.8-0.8-0.60.30.60.1-0.2-0.9-0.1-0.20.3-0.80.40.3
Delay discount exponential model param0.20.20.7-0.30.6-0.10.80.2-0.1-0.30.3-0.0-0.70.00.7-0.7
Delay discount hyperbolic model param0.20.30.7-0.10.70.10.8-0.0-0.2-0.10.5-0.2-0.8-0.10.6-0.8
Fecal boli incidents, locomotor time 10.60.73.00.3-1.7-0.2-1.3-0.20.20.2-0.30.20.40.3-1.70.4
Change in fecal boli incidents, locomotor task0.60.51.3-0.00.1-1.1-0.60.80.90.0-1.21.10.60.90.20.6
Time >=10cm from walls, locomotor time 10.30.31.0-0.8-1.0-0.30.10.60.4-0.8-0.30.30.30.1-0.30.3
Bouts of movement, locomotor time 11.31.42.80.20.91.51.1-1.3-1.50.11.4-1.5-1.2-1.70.6-1.2
Total resting periods, locomotor time 10.80.91.80.20.31.30.7-1.2-1.20.11.3-1.3-1.0-1.30.1-1.0
Rest time, locomotor task time 10.30.32.0-0.7-1.4-0.3-0.10.00.2-0.7-0.10.30.3-0.0-0.70.3
Distance moved, locomotor task time 10.91.03.00.01.70.91.4-0.4-0.80.00.8-0.9-0.9-0.91.5-0.9
Vertical activity count, locomotor time 10.70.71.90.31.40.81.1-0.3-0.70.30.7-0.8-1.0-0.61.1-1.0
Time >=10cm from walls, locomotor time 21.61.75.2-1.10.81.22.3-0.5-1.4-1.20.9-1.2-0.7-1.52.2-0.7
Bouts of movement, locomotor time 24.34.68.1-0.21.42.52.8-2.0-2.5-0.32.3-2.5-2.3-2.82.0-2.3
Total resting periods, locomotor time 23.23.46.7-0.30.82.22.4-1.8-2.2-0.41.9-2.2-2.0-2.61.4-2.0
Rest time, locomotor task time 23.33.910.0-2.3-3.2-2.1-0.61.92.0-2.4-2.12.11.80.9-1.11.8
Distance moved, locomotor task time 23.54.19.5-0.12.82.12.8-1.2-2.0-0.11.9-2.1-1.8-1.93.1-1.8
Vertical activity count, locomotor time 24.34.812.31.43.52.31.6-1.7-2.11.52.3-2.3-2.4-1.42.4-2.4
Weight adjusted by age1.51.75.3-0.9-0.91.22.3-1.1-1.4-1.01.0-1.2-1.3-1.81.2-1.3
Seeking ratio, delayed vs. immediate footshock0.40.51.10.50.60.7-0.3-1.0-0.70.40.7-0.6-0.8-0.9-0.6-0.8
Locomotion in novel chamber0.20.31.2-0.8-1.1-0.10.9-0.1-0.1-0.90.20.00.1-0.5-0.00.1
Locomotion in novel chamber post-restriction0.20.20.60.70.1-0.3-0.30.00.20.8-0.60.30.60.5-0.40.6
Progressive ratio0.40.43.7-0.3-1.9-0.4-0.00.00.5-0.4-0.40.40.20.2-0.90.2
Food seeking constrained by brief footshock0.40.51.71.20.6-0.1-0.7-0.20.31.3-0.30.20.61.1-0.70.6
Seeking ratio, punishment vs. effort0.50.64.60.92.10.4-0.3-0.2-0.31.00.2-0.40.10.30.60.1
Run reversals in cocaine runway, females9.39.315.2-0.22.03.82.7-2.4-3.7-0.33.7-3.9-3.9-3.71.5-3.9
Run reversals in cocaine runway, males0.40.41.7-0.6-1.3-0.5-0.10.60.7-0.6-0.60.50.50.30.10.5
Latency to leave start box in cocaine runway1.31.45.3-1.60.20.72.10.5-0.5-1.50.8-0.7-0.7-0.92.3-0.7
Latency to leave start box in cocaine runway, F1.92.15.1-1.4-0.41.42.3-0.6-1.4-1.51.5-1.4-1.4-1.81.6-1.4
Latency to leave start box in cocaine runway, M0.70.73.7-0.70.8-0.11.41.10.3-0.70.10.10.10.21.90.1
Cd content in liver1.31.47.1-1.2-2.7-0.90.41.01.0-1.3-1.10.91.10.5-0.11.1
Co content in liver0.10.21.1-0.1-1.10.20.6-0.2-0.2-0.20.3-0.2-0.2-0.3-0.3-0.2
Cu content in liver0.30.40.80.1-0.1-0.8-0.60.70.70.2-0.60.80.80.9-0.10.8
Fe content in liver0.10.10.1-0.10.0-0.3-0.40.30.4-0.1-0.20.30.30.30.00.3
K content in liver2.52.54.2-0.4-0.5-2.0-1.51.82.0-0.4-1.82.01.91.8-0.81.9
Mg content in liver4.04.17.1-1.2-0.3-2.6-1.12.72.4-1.1-2.42.62.52.20.32.5
Mn content in liver3.84.37.8-1.0-1.1-2.5-1.52.32.3-0.9-2.62.52.82.3-0.72.8
Na content in liver1.41.52.8-0.9-0.7-1.5-1.31.71.3-0.9-1.31.51.31.1-0.51.3
Rb content in liver2.12.64.2-1.0-1.4-2.0-0.52.12.0-1.0-1.82.01.81.8-0.31.8
Se content in liver1.11.33.2-1.7-1.8-1.00.11.10.9-1.7-0.91.01.00.3-1.21.0
Sr content in liver1.21.12.20.60.51.20.2-1.3-1.50.61.2-1.2-1.3-1.0-0.6-1.3
Zn content in liver1.41.62.3-0.9-1.5-1.5-0.81.51.1-0.9-1.41.51.41.1-1.01.4