Hub : Genes

Cyb5d2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000036942 0.04 0.03 9.5e-04 0.02 0.01 0.01 0.01 2.3e-03 3.5e-02 2.7e-02 2.5e-02
2 Adipose alternative TSS ENSRNOT00000097276 0.04 0.03 1.2e-03 0.02 0.01 0.01 0.01 2.8e-03 3.9e-02 2.6e-02 2.8e-02
3 Adipose gene expression ENSRNOG00000024553 0.03 0.03 1.8e-03 0.02 0.01 0.01 0.01 1.8e-03 4.6e-02 4.6e-02 1.8e-02
4 Adipose mRNA stability ENSRNOG00000024553 0.09 0.06 9.0e-09 0.03 0.05 0.05 0.05 1.6e-04 2.0e-06 2.3e-06 6.2e-06
5 BLA gene expression ENSRNOG00000024553 0.07 0.05 3.4e-03 0.03 0.04 0.03 0.04 6.1e-03 3.0e-03 6.4e-03 4.9e-03
6 BLA intron excision ratio chr10:57407529:57412543 0.08 0.06 2.4e-03 0.05 0.04 0.02 0.05 9.5e-04 3.6e-03 3.3e-02 1.8e-03
7 Brain intron excision ratio chr10:57400881:57407389 0.03 0.03 2.9e-03 0.04 0.03 0.04 0.03 3.2e-04 1.2e-03 2.1e-04 4.9e-04
8 Liver gene expression ENSRNOG00000024553 0.2 0.12 0.0e+00 0.13 0.14 0.14 0.14 4.5e-14 3.9e-15 5.9e-15 4.9e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.30.91.0-0.90.9-1.00.9-0.9-0.9-0.9-1.0
BMI without tail0.61.31.7-1.21.2-1.01.3-1.1-1.0-1.1-1.3
Body weight0.72.97.0-1.61.6-1.52.6-1.0-1.5-1.3-2.0
Epididymis fat weight4.811.212.6-3.53.5-3.13.4-3.2-3.1-3.4-3.5
Glucose0.71.13.20.9-0.90.9-1.80.30.90.61.2
Heart weight1.31.82.2-1.51.5-1.21.2-1.4-1.2-1.4-1.4
Left kidney weight0.10.20.4-0.70.7-0.2-0.0-0.7-0.2-0.7-0.3
Right kidney weight0.10.10.3-0.60.6-0.1-0.0-0.5-0.1-0.5-0.2
Tail length1.54.610.3-2.02.0-1.83.2-1.4-1.8-1.7-2.6
Length with tail0.62.06.2-1.31.3-1.12.5-0.6-1.1-1.0-1.8
Length without tail0.61.33.0-1.01.0-1.11.7-0.6-1.1-0.9-1.3
Liver weight, left0.10.10.6-0.20.2-0.30.80.1-0.3-0.0-0.4
Liver weight, right1.01.72.5-1.31.3-1.31.6-1.1-1.3-1.2-1.4
Parametrial fat weight14.828.931.6-5.55.5-5.25.4-4.9-5.4-5.4-5.6
Retroperitoneal fat weight0.10.30.6-0.50.5-0.60.0-0.8-0.6-0.5-0.4
Intraocular pressure0.71.01.9-1.11.1-0.9-0.2-1.4-0.9-1.4-0.5
Extensor digitorum longus weight4.016.218.0-4.14.1-4.23.2-4.2-4.2-4.1-4.0
Soleus weight3.19.013.5-2.92.9-3.03.7-2.3-3.0-2.7-3.3
Tibialis anterior weight4.515.516.7-3.93.9-4.03.8-3.8-4.0-3.8-4.1
Tibia length0.10.30.90.4-0.40.50.71.00.50.50.0
Number of licking bursts0.30.40.40.6-0.60.6-0.60.60.60.60.6
Food consumed during 24 hour testing period0.40.40.80.7-0.70.6-0.10.90.60.80.5
Times rat made contact with spout1.21.31.71.2-1.21.3-0.61.31.31.21.0
Mean time between licks in bursts2.12.93.1-1.71.7-1.81.7-1.5-1.8-1.7-1.7
Mean num. licks in bursts0.00.00.10.0-0.00.10.20.20.10.1-0.1
Std. dev. time between licks in bursts0.70.80.9-0.90.9-1.00.8-0.8-1.0-0.9-0.9
Water consumed over 24 hours3.13.75.52.0-2.02.0-0.82.32.02.21.6
Indifference point 0 sec1.22.03.01.3-1.31.7-0.61.71.71.51.2
Indifference point AUC1.11.32.4-1.31.3-0.7-0.0-1.5-0.9-1.5-0.7
Indifference point function ln k4.86.810.32.8-2.82.5-1.13.22.53.12.2
Indifference point function log k4.86.810.32.8-2.82.5-1.13.22.53.12.2
Delay discounting total patch changes 0 sec0.81.32.11.0-1.01.4-0.51.41.41.20.9
Delay discounting total patch changes 12 sec0.91.21.8-1.31.3-0.80.6-1.3-0.9-1.4-1.0
Delay discounting total patch changes 18 sec0.50.61.0-1.01.0-0.40.5-1.0-0.5-1.0-0.8
Delay discounting total patch changes 24 sec0.20.20.5-0.70.7-0.0-0.1-0.7-0.1-0.7-0.2
Delay discounting total patch changes 6 sec0.71.02.0-1.21.2-0.60.2-1.4-0.6-1.3-0.8
Delay discounting time to switch 0 sec1.62.42.9-1.51.5-1.71.3-1.7-1.7-1.5-1.6
Delay discounting water rate 0 sec1.01.51.81.3-1.31.1-1.21.21.11.31.3
Delay discounting water rate 12 sec0.40.51.0-0.60.6-0.90.8-0.5-1.0-0.6-0.7
Delay discounting water rate 18 sec0.10.10.40.3-0.30.10.50.70.10.50.0
Delay discounting water rate 24 sec0.10.10.30.1-0.1-0.5-0.1-0.0-0.60.10.1
Delay discounting water rate 6 sec0.40.50.70.9-0.90.3-0.80.80.30.80.8
Locomotor activity0.71.21.5-1.11.1-1.20.9-1.1-1.2-1.1-1.0
Locomotor testing distance3.04.96.3-2.22.2-2.51.4-2.5-2.5-2.3-2.0
Locomotor testing rearing3.35.27.2-2.42.4-2.21.2-2.7-2.3-2.6-2.0
Light reinforcement 11.52.73.6-1.81.8-1.61.0-1.8-1.6-1.9-1.5
Light reinforcement 20.10.10.2-0.40.4-0.3-0.1-0.4-0.4-0.5-0.1
Reaction time number correct0.10.10.30.1-0.1-0.60.40.0-0.50.2-0.2
Reaction time mean minus median0.70.91.30.9-0.91.1-1.10.81.00.81.0
Reaction time mean minus median AUC0.10.20.30.4-0.40.5-0.50.20.40.20.4
Reaction time num false alarms1.31.82.41.3-1.31.4-1.31.31.51.21.4
Reaction time num false alarms AUC1.11.51.81.2-1.21.2-1.31.21.31.11.3
Reaction time trials correct on left0.10.10.30.1-0.1-0.60.40.0-0.50.2-0.2
Reaction time trials on left0.10.10.30.1-0.1-0.60.30.0-0.50.2-0.2
Reaction time mean0.30.40.60.6-0.60.8-0.60.50.70.50.6
Reaction time mean AUC0.60.91.20.9-0.91.1-1.00.71.00.81.0
Median of all reaction times0.10.10.20.3-0.30.5-0.40.20.40.30.3
Reaction time omissions0.30.50.6-0.80.8-0.60.3-0.8-0.7-0.8-0.6
Reaction time false alarm rate0.81.21.80.9-0.91.3-1.21.01.30.81.1
Reaction time premature initiation rate1.31.82.71.6-1.61.2-0.41.71.11.61.0
Reaction time premature initiations0.91.32.41.4-1.40.8-0.11.50.71.50.8
Std. dev. reaction times1.52.12.61.4-1.41.6-1.41.31.51.31.5
Reaction time trials completed0.10.10.30.1-0.1-0.60.30.0-0.50.2-0.2
Reaction time trials AUC0.10.10.20.2-0.2-0.50.30.1-0.40.3-0.1
Social response proportion0.30.41.20.3-0.30.11.11.00.10.6-0.2
Social responses2.63.44.3-1.91.9-1.82.1-1.5-1.8-1.8-1.9
Social time1.41.82.9-1.21.2-1.51.7-1.0-1.4-1.2-1.5
Conditioned locomotion1.01.21.71.1-1.11.1-1.30.91.11.11.2
Cocaine response after cond. corrected0.20.30.60.5-0.50.60.10.80.60.50.3
Cocaine response after cond. not corrected0.10.10.20.1-0.10.30.40.40.30.2-0.0
Cocaine response before conditioning0.91.11.2-1.01.0-1.00.9-1.1-1.0-1.1-1.1
Saline control response0.60.80.9-1.01.0-0.80.8-0.9-0.8-0.9-0.9
Condit. Reinf. active minus inactive responses0.30.40.80.7-0.70.6-0.00.90.60.70.5
Condit. Reinf. active-inactive response ratio0.70.71.10.9-0.90.9-0.31.10.90.90.7
Condit. Reinf. active responses0.10.10.30.4-0.40.30.00.60.30.40.3
Condit. Reinf. inactive responses0.10.10.1-0.30.3-0.4-0.0-0.3-0.4-0.3-0.1
Condit. Reinf. lever presses0.40.61.00.8-0.80.7-1.00.60.70.60.9
Condit. Reinf. lever reinforcers received0.10.10.30.4-0.40.3-0.10.60.30.40.3
Pavlov. Cond. lever latency2.12.93.6-1.71.7-1.71.9-1.5-1.7-1.5-1.9
Pavlov. Cond. magazine entry latency1.21.41.61.3-1.31.2-1.01.21.21.21.2
Pavlov. Cond. change in total contacts0.91.31.51.1-1.11.2-1.11.11.21.11.2
Pavlov. Cond. index score1.41.82.81.3-1.31.3-1.71.11.31.11.5
Pavlov. Cond. latency score1.62.03.51.4-1.41.3-1.91.11.31.21.6
Pavlov. Cond. lever contacts0.70.91.40.9-0.90.9-1.20.80.90.81.1
Pavlov. Cond. magazine entry number0.91.11.3-1.11.1-1.01.1-1.0-1.0-0.9-1.1
Pavlov. Cond. intertrial magazine entries1.21.51.6-1.21.2-1.31.2-1.1-1.3-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.1.41.92.81.3-1.31.3-1.71.11.31.21.5
Pavlov. Cond. response bias1.11.51.81.2-1.21.2-1.31.11.21.11.3
Conditioned reinforcement - actives1.21.21.8-1.11.1-1.20.8-1.1-1.3-1.1-1.0
Conditioned reinforcement - inactives1.72.02.5-1.51.5-1.31.0-1.6-1.4-1.5-1.4
Conditioned locomotion0.20.30.5-0.50.5-0.6-0.2-0.7-0.7-0.6-0.2
Intermittent access intake day 1-15 change0.30.30.8-0.30.3-0.5-0.6-0.9-0.5-0.5-0.1
Intermittent access intake escalation0.20.20.8-0.10.1-0.4-0.9-0.7-0.3-0.40.2
Intermittent access intake escalation 20.50.52.30.6-0.60.3-1.50.10.30.40.9
Intermitt. access day 1 inactive lever presses0.50.51.20.8-0.80.5-1.10.40.50.80.8
Intermitt. access day 15 inactive lever presses0.20.20.50.6-0.60.3-0.20.50.40.70.3
Intermitt. access escalation Index1.31.12.6-1.11.1-0.81.6-0.6-0.8-0.9-1.3
Intermittent access day 1 total infusions2.83.13.9-2.02.0-1.61.4-1.8-1.7-1.9-1.7
Intermittent access day 15 total infusions3.84.26.5-2.22.2-2.10.7-2.6-2.2-2.4-1.7
Intermittent access terminal intake (last 3 days)4.44.86.1-2.32.3-2.21.4-2.4-2.2-2.5-2.0
Intermittent access total infusions2.52.83.5-1.81.8-1.70.9-1.9-1.8-1.8-1.4
Intermittent access day 1 locomotion1.92.03.1-1.21.2-1.70.9-1.6-1.8-1.3-1.3
Intermittent access day 15 total locomotion0.70.81.6-0.70.7-1.00.0-1.3-1.1-0.9-0.6
Intermittent access total locomotion0.70.71.7-0.60.6-1.20.3-1.0-1.3-0.7-0.7
Intermittent access standard deviation1.61.73.8-1.21.2-1.4-0.4-1.9-1.4-1.5-0.8
Cocaine induced anxiety2.83.34.22.0-2.01.5-1.51.91.52.01.8
Post-drug Anxiety0.70.81.11.0-1.00.9-0.51.10.81.00.8
Baseline Anxiety1.31.42.1-1.41.4-0.91.0-1.2-0.9-1.5-1.2
Lifetime Intake3.84.35.4-2.22.2-2.11.1-2.3-2.2-2.3-1.8
Incentive Sensitization - Responses0.20.20.3-0.50.5-0.50.4-0.3-0.5-0.3-0.3
Incentive Sensitization - Breakpoint0.20.20.2-0.40.4-0.50.3-0.3-0.5-0.3-0.3
Progressive ratio test 1 active lever presses1.91.92.1-1.51.5-1.31.3-1.4-1.3-1.4-1.4
Progressive ratio test 1 breakpoint2.82.93.3-1.81.8-1.51.8-1.6-1.6-1.7-1.8
Progressive ratio test 1 inactive lever presses1.11.21.7-1.11.1-1.30.4-1.2-1.3-1.1-0.8
Progressive ratio test 2 active lever presses1.11.21.4-1.21.2-1.10.9-1.0-1.1-1.1-1.0
Progressive ratio test 2 breakpoint0.60.60.8-0.80.8-0.90.6-0.7-0.9-0.8-0.7
Progressive ratio test 2 inactive lever presses2.02.32.8-1.51.5-1.70.9-1.7-1.6-1.5-1.3
Total sessions with >9 infusions3.03.23.9-1.91.9-1.81.3-2.0-1.9-1.9-1.7
Short access day 1 total inactive lever presses0.10.10.2-0.20.2-0.30.3-0.4-0.4-0.2-0.4
Short access day 10 total inactive lever presses0.20.30.50.6-0.60.3-0.20.60.30.70.4
Short access day 1 total infusions2.32.44.4-1.61.6-1.50.5-2.1-1.5-1.8-1.3
Short access day 10 total infusions1.92.12.5-1.61.6-1.40.9-1.5-1.5-1.6-1.3
Short access total infusions3.74.05.8-2.12.1-2.01.0-2.4-2.1-2.3-1.7
Short access day 1 locomotion0.50.51.2-0.60.6-0.7-0.1-1.1-0.8-0.8-0.5
Short access day 10 total locomotion0.30.30.9-0.30.3-0.9-0.0-0.7-0.9-0.4-0.3
Short access total locomotion0.30.30.8-0.40.4-0.8-0.0-0.8-0.9-0.5-0.4
Compulsive drug intake0.80.81.50.9-0.90.8-0.11.20.81.10.7
One hour access (0.3 mA shock)1.82.12.6-1.61.6-1.50.9-1.5-1.6-1.6-1.2
One hour access (shock baseline)2.52.93.7-1.81.8-1.80.8-1.9-1.8-1.9-1.4
Number of responses in last shaping day0.10.10.6-0.00.0-0.3-0.8-0.4-0.3-0.20.3
Context. condit. distance diff. score1.51.82.1-1.41.4-1.41.5-1.1-1.4-1.2-1.4
Locomotion velocity, session 12.93.14.9-1.81.8-1.62.2-1.4-1.6-1.6-2.0
Locomotion distance, session 11.21.51.8-1.31.3-1.11.0-1.3-1.1-1.3-1.2
Locomotion velocity, session 20.10.10.30.3-0.30.30.30.50.30.30.1
Locomotion distance, session 20.30.40.8-0.60.6-0.50.9-0.4-0.5-0.5-0.7
Locomotion velocity, session 32.73.13.41.8-1.81.7-1.71.71.71.81.8
Locomotion distance, session 30.20.20.30.5-0.50.4-0.40.50.40.50.4
Stereotopy head waving bouts, day 30.00.00.10.2-0.20.00.00.20.00.20.0
Stereotopy head waving duration, day 30.10.10.60.1-0.10.0-0.8-0.30.0-0.00.3
Locomotion velocity, session 70.00.00.1-0.20.2-0.20.1-0.2-0.2-0.3-0.2
Locomotion distance, session 70.00.00.00.1-0.10.00.00.10.00.10.1
Stereotopy head waving bouts, day 71.21.41.6-1.11.1-1.31.2-1.2-1.3-1.1-1.3
Stereotopy head waving duration, day 71.51.92.1-1.31.3-1.41.4-1.3-1.4-1.2-1.5
Locomotion velocity, session 81.31.51.6-1.31.3-1.31.1-1.2-1.3-1.2-1.2
Locomotion distance, session 82.03.04.4-1.81.8-1.72.1-1.3-1.7-1.6-1.9
Degree of sensitization distance0.80.91.0-1.01.0-0.90.8-0.9-0.9-1.0-0.9
Degree of sensitization stereotypy1.51.72.5-1.21.2-1.31.6-1.1-1.3-1.1-1.4
Condit. Reinf. active minus inactive responses0.70.81.30.9-0.90.9-0.21.10.91.00.7
Condit. Reinf. active-inactive response ratio0.50.50.80.7-0.70.8-0.20.90.80.80.6
Condit. Reinf. active responses0.40.51.00.7-0.70.8-0.11.00.80.80.5
Condit. Reinf. inactive responses0.00.00.10.2-0.20.2-0.20.20.20.10.2
Incentive salience index mean0.70.91.70.9-0.91.0-0.01.31.01.00.6
Condit. Reinf. lever presses0.50.61.70.7-0.70.80.61.30.80.90.3
Time in familiar zone, hab. session 10.00.00.1-0.10.1-0.1-0.3-0.3-0.1-0.10.0
Time in novel zone, hab. session 10.10.10.30.4-0.40.30.10.60.30.40.2
Total zone transitions, hab. session 14.66.58.5-2.72.7-2.61.6-2.9-2.6-2.8-2.4
Total locomotion distance, hab. session 10.40.60.7-0.80.8-0.70.6-0.8-0.7-0.8-0.7
Locomotion velocity, hab. session 10.40.60.8-0.90.9-0.80.5-0.9-0.8-0.9-0.7
Time in familiar zone, hab. session 20.00.00.10.2-0.20.20.20.30.20.30.1
Time in novel zone, hab. session 20.50.50.70.7-0.70.6-0.80.50.60.60.8
Total zone transitions, hab. session 23.14.04.9-2.22.2-1.91.6-2.1-1.9-2.2-2.0
Total locomotion distance, hab. session 20.60.81.1-1.01.0-0.80.7-0.9-0.8-1.1-0.9
Locomotion velocity, hab. session 20.60.91.3-1.01.0-0.80.7-1.0-0.8-1.1-0.9
Novel to familiar place preference ratio0.00.00.10.0-0.0-0.0-0.3-0.2-0.0-0.00.1
Novelty place preference0.00.00.00.1-0.1-0.0-0.1-0.0-0.00.10.1
Time in novel zone, NPP test0.00.00.00.0-0.0-0.10.00.0-0.10.1-0.0
Total zone transitions, NPP test3.44.95.9-2.42.4-2.11.6-2.4-2.1-2.4-2.1
Total locomotion distance, NPP test0.10.20.4-0.50.5-0.3-0.1-0.6-0.3-0.6-0.3
Locomotion velocity, NPP test0.10.10.3-0.10.10.0-0.5-0.40.0-0.30.1
Pavlov. Cond. lever latency1.72.23.2-1.51.5-1.60.6-1.8-1.6-1.6-1.3
Pavlov. Cond. magazine entry latency2.12.74.61.6-1.61.8-0.52.21.81.81.3
Pavlov. Cond. change in total contacts2.52.73.21.6-1.61.8-1.31.81.81.61.6
Pavlov. Cond. index score1.31.63.01.2-1.21.4-0.21.71.41.41.0
Pavlov. Cond. latency score1.31.73.21.2-1.21.4-0.11.81.41.50.9
Pavlov. Cond. lever contacts1.11.32.01.1-1.11.3-0.31.41.31.20.9
Pavlov. Cond. magazine entry number1.31.62.5-1.21.2-1.40.6-1.6-1.4-1.3-1.1
Pavlov. Cond. intertrial magazine entries2.42.94.4-1.71.7-1.80.9-2.1-1.8-1.8-1.6
Pavlov. Cond. lever-magazine prob. diff.1.31.62.81.2-1.21.4-0.31.71.41.41.0
Pavlov. Cond. response bias1.41.72.81.3-1.31.5-0.41.71.51.41.1
Bone: apparent density0.40.72.1-0.80.8-0.71.5-0.3-0.7-0.5-1.0
Bone surface1.22.12.4-1.51.5-1.51.5-1.3-1.5-1.3-1.5
Bone volume1.72.93.2-1.71.7-1.81.7-1.6-1.8-1.6-1.8
Bone: connectivity density1.01.63.0-1.21.2-1.21.7-0.8-1.2-1.0-1.4
Bone: cortical apparent density1.41.82.01.3-1.31.4-1.41.31.41.21.4
Bone: cortical area0.20.20.70.4-0.40.4-0.80.20.40.40.6
Bone: cortical porosity1.11.12.01.1-1.11.0-0.11.41.01.40.8
Bone: cortical porosity1.21.32.21.2-1.21.1-0.31.41.11.50.9
Bone: cortical thickness2.74.54.82.2-2.22.1-1.92.12.12.22.1
Bone: cortical thickness3.74.35.92.1-2.12.2-1.22.42.22.31.9
Bone: cortical tissue density1.11.51.71.2-1.21.3-1.21.21.31.11.3
Bone: elastic displacement0.30.40.80.5-0.50.6-0.90.40.60.50.7
Bone: elastic work1.52.02.41.3-1.31.5-1.51.21.51.31.5
Bone: endosteal estimation2.55.38.1-2.42.4-2.31.2-2.8-2.3-2.5-2.1
Bone: endosteal perimeter2.85.78.3-2.52.5-2.41.3-2.9-2.4-2.6-2.2
Bone: final force0.61.01.2-1.11.1-1.00.7-1.1-1.0-1.0-0.9
Bone: final moment0.60.91.3-1.01.0-1.00.6-1.1-1.0-1.0-0.9
Bone: marrow area2.45.37.9-2.42.4-2.31.2-2.8-2.3-2.5-2.1
Bone: maximum diameter0.30.61.3-0.80.8-0.7-0.0-1.1-0.7-0.9-0.6
Bone: maximum force0.61.01.3-1.11.1-1.00.6-1.2-1.0-1.1-0.9
Bone: maximum moment0.61.01.5-1.11.1-1.00.5-1.2-1.0-1.1-0.9
Bone: minimum diameter1.83.34.6-1.91.9-1.91.1-2.1-1.9-2.0-1.7
Bone: periosteal estimation0.91.93.3-1.41.4-1.40.4-1.8-1.4-1.5-1.2
Bone: periosteal perimeter0.60.91.7-1.01.0-1.00.3-1.3-1.0-1.1-0.8
Bone: post-yield work0.60.81.3-0.90.9-0.91.2-0.7-0.9-0.8-1.0
Bone: stiffness2.64.14.8-2.02.0-2.02.2-1.7-2.0-1.9-2.1
Bone: tissue strength0.00.00.20.0-0.00.1-0.4-0.10.1-0.00.2
Bone: trabecular number0.10.20.9-0.20.2-0.10.90.2-0.10.0-0.4
Bone: trabecular spacing0.00.10.30.0-0.0-0.1-0.6-0.3-0.1-0.10.2
Bone: trabecular thickness0.20.20.4-0.50.5-0.50.7-0.3-0.5-0.4-0.5
Bone: trabecular tissue density2.23.13.61.7-1.71.9-1.91.51.91.61.8
Breakpoint value in progressive ratio session1.11.22.1-1.31.3-0.51.4-0.8-0.6-1.1-1.2
Distance traveled before self-admin0.10.10.3-0.30.3-0.1-0.5-0.6-0.1-0.40.0
Distance traveled after self-admin5.96.58.9-2.62.6-2.61.5-3.0-2.6-2.7-2.4
Delta time in closed arm before/after self-admin0.80.81.5-0.90.9-0.70.5-1.2-0.7-1.1-0.9
Delta time in open arm before/after self-admin1.01.01.2-1.01.0-1.00.9-1.0-1.1-1.0-1.0
Diff in mean of infusions in LGA sessions0.10.10.7-0.00.00.10.80.3-0.00.2-0.4
Extinction: sum of active levers before priming1.61.73.1-1.31.3-1.01.7-1.0-1.1-1.1-1.5
Active lever presses in extinction session 61.91.92.4-1.51.5-1.01.4-1.3-1.1-1.4-1.5
Delta distance traveled before/after self-admin4.64.95.9-2.22.2-2.42.0-2.2-2.4-2.2-2.3
Delta ambulatory time before/after self-admin2.83.04.0-1.61.6-2.01.6-1.7-2.0-1.6-1.8
Time in closed arm before self-admin0.20.20.50.4-0.40.20.60.70.30.5-0.0
Time in closed arm after self-admin0.10.10.20.4-0.40.2-0.00.30.30.40.1
Time in open arm before self-admin1.31.42.71.0-1.01.3-1.60.71.20.91.3
Time in open arm after self-admin0.20.30.5-0.50.5-0.3-0.5-0.7-0.5-0.6-0.0
Sum of active levers in priming session hrs 5-60.50.52.1-0.60.6-0.31.5-0.2-0.5-0.4-0.9
Time to tail flick, vehicle, before self-admin0.30.31.5-0.40.4-0.31.2-0.1-0.2-0.3-0.8
Time to tail flick, vehicle, after self-admin0.10.10.1-0.10.1-0.40.2-0.4-0.4-0.2-0.3
Time to tail flick, test, before self-admin3.33.35.02.0-2.01.7-0.82.21.62.11.5
Time to tail flick, test, after self-admin0.60.71.10.8-0.80.8-0.31.00.90.90.7
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.10.1-0.4-0.7-0.6-0.5-0.30.1
Delta time to tail flick, test, before/after SA1.41.21.9-1.31.3-1.00.4-1.4-0.9-1.4-0.9
Ambulatory time before self-admin0.10.10.2-0.20.20.2-0.5-0.20.2-0.20.2
Ambulatory time after self-admin3.33.74.2-1.91.9-2.01.6-2.1-2.0-2.0-1.9
Total heroin consumption0.81.04.1-0.90.9-0.62.0-0.1-0.6-0.6-1.2
Area under the delay curve0.00.00.1-0.10.10.1-0.3-0.10.1-0.10.2
Delay disc. indifference point, 0s delay2.22.43.1-1.61.6-1.51.1-1.8-1.5-1.6-1.5
Delay disc. indifference point, 16s delay0.20.20.5-0.60.6-0.4-0.1-0.7-0.4-0.6-0.3
Delay disc. indifference point, 2s delay0.20.20.30.4-0.40.5-0.60.40.50.40.5
Delay disc. indifference point, 24s delay0.80.81.10.8-0.81.0-0.71.01.00.80.9
Delay disc. indifference point, 4s delay0.40.50.6-0.70.7-0.70.4-0.8-0.7-0.7-0.6
Delay disc. indifference point, 8s delay0.00.00.0-0.10.1-0.0-0.1-0.1-0.0-0.10.0
Delay discount exponential model param0.00.10.1-0.10.1-0.30.4-0.2-0.3-0.1-0.3
Delay discount hyperbolic model param0.00.00.1-0.00.0-0.20.3-0.1-0.2-0.0-0.2
Fecal boli incidents, locomotor time 10.40.50.80.8-0.80.6-0.40.70.60.90.6
Change in fecal boli incidents, locomotor task0.60.50.70.7-0.70.8-0.60.90.80.70.7
Time >=10cm from walls, locomotor time 10.30.30.50.5-0.50.7-0.30.70.70.60.5
Bouts of movement, locomotor time 10.50.50.90.8-0.80.7-0.20.90.70.80.6
Total resting periods, locomotor time 11.61.82.51.4-1.41.4-0.71.61.41.51.2
Rest time, locomotor task time 10.70.80.90.8-0.81.0-0.90.91.00.81.0
Distance moved, locomotor task time 11.31.41.7-1.31.3-1.20.9-1.3-1.2-1.3-1.1
Vertical activity count, locomotor time 11.41.41.5-1.21.2-1.21.0-1.2-1.2-1.2-1.2
Time >=10cm from walls, locomotor time 20.80.81.10.8-0.81.0-0.61.01.01.00.9
Bouts of movement, locomotor time 21.21.31.81.2-1.21.2-0.61.31.21.31.0
Total resting periods, locomotor time 20.70.81.10.9-0.90.9-0.41.10.91.00.8
Rest time, locomotor task time 21.31.51.81.3-1.31.1-1.01.31.11.31.2
Distance moved, locomotor task time 21.92.23.2-1.71.7-1.40.7-1.7-1.4-1.8-1.3
Vertical activity count, locomotor time 20.91.01.4-1.21.2-0.90.6-1.0-0.9-1.1-0.8
Weight adjusted by age3.33.74.2-2.02.0-1.91.5-2.0-1.9-2.0-1.9
Seeking ratio, delayed vs. immediate footshock0.80.91.11.0-1.01.0-1.00.71.00.90.9
Locomotion in novel chamber0.30.42.10.2-0.2-0.2-1.4-0.4-0.3-0.00.6
Locomotion in novel chamber post-restriction0.40.50.60.8-0.80.7-0.70.70.70.70.7
Progressive ratio0.40.51.0-0.70.7-0.60.3-1.0-0.6-0.9-0.6
Food seeking constrained by brief footshock0.10.10.30.3-0.30.5-0.40.30.50.30.4
Seeking ratio, punishment vs. effort0.91.11.71.1-1.11.0-0.71.31.01.31.0
Run reversals in cocaine runway, females0.20.20.30.5-0.50.3-0.50.40.30.50.5
Run reversals in cocaine runway, males0.90.91.8-0.90.9-1.0-0.1-1.3-1.0-1.1-0.6
Latency to leave start box in cocaine runway0.00.00.20.0-0.00.40.00.20.40.00.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.10.10.30.50.10.3-0.1-0.2
Latency to leave start box in cocaine runway, M0.30.30.4-0.60.6-0.50.3-0.5-0.5-0.6-0.4
Cd content in liver1.41.61.8-1.31.3-1.21.1-1.3-1.2-1.3-1.3
Co content in liver0.30.30.3-0.60.6-0.60.5-0.5-0.6-0.6-0.6
Cu content in liver2.73.24.21.9-1.91.9-1.12.11.92.01.6
Fe content in liver0.10.10.5-0.20.2-0.20.70.1-0.2-0.1-0.4
K content in liver0.10.10.5-0.30.3-0.20.70.0-0.2-0.2-0.4
Mg content in liver0.00.00.00.0-0.00.1-0.1-0.00.10.00.1
Mn content in liver1.11.22.01.1-1.11.2-0.51.41.21.21.0
Na content in liver0.00.00.10.0-0.00.1-0.3-0.20.1-0.10.1
Rb content in liver0.81.01.2-1.01.0-1.00.7-1.1-1.0-1.1-0.9
Se content in liver1.41.61.81.3-1.31.3-1.21.21.31.31.3
Sr content in liver2.11.92.2-1.41.4-1.51.2-1.4-1.5-1.4-1.4
Zn content in liver0.20.30.30.6-0.60.5-0.50.50.50.50.5