Hub : Genes

Pwwp3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000024549 0.27 0.13 0.0e+00 0.28 0.32 0.3 0.31 2.0e-15 1.3e-17 1.6e-16 3.2e-17
2 Brain gene expression ENSRNOG00000024549 0.33 0.12 0.0e+00 0.31 0.34 0.34 0.34 5.2e-29 3.7e-32 1.5e-32 2.4e-32
3 Brain intron excision ratio chr7:9480256:9481942 0.03 0.02 8.4e-03 0.03 0.02 0.03 0.02 1.2e-03 9.8e-03 2.0e-03 2.5e-03
4 Eye gene expression ENSRNOG00000024549 0.76 0.14 4.0e-07 0.21 0.19 0.21 0.21 4.2e-04 7.7e-04 3.7e-04 3.2e-04
5 IL gene expression ENSRNOG00000024549 0.32 0.17 1.9e-06 0.11 0.12 0.09 0.12 1.5e-03 9.4e-04 3.8e-03 7.3e-04
6 LHb gene expression ENSRNOG00000024549 0.22 0.13 1.0e-04 0.14 0.15 0.16 0.15 3.2e-04 1.9e-04 1.3e-04 2.3e-04
7 NAcc gene expression ENSRNOG00000024549 0.17 0.09 5.7e-13 0.18 0.16 0.18 0.18 3.6e-13 2.4e-12 2.5e-13 2.7e-13
8 NAcc intron excision ratio chr7:9474881:9475937 0.03 0.02 6.2e-03 0.01 0.02 0.01 0.01 3.3e-02 1.4e-02 3.2e-02 2.4e-02
9 NAcc intron excision ratio chr7:9474884:9475937 0.03 0.02 6.0e-03 0.01 0.02 0.01 0.02 3.2e-02 1.3e-02 2.9e-02 2.1e-02
10 OFC gene expression ENSRNOG00000024549 0.46 0.2 8.2e-10 0.38 0.32 0.32 0.36 7.4e-10 1.8e-08 2.4e-08 2.3e-09
11 PL gene expression ENSRNOG00000024549 0.23 0.11 0.0e+00 0.24 0.26 0.26 0.26 1.2e-18 6.9e-20 4.4e-20 8.9e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail7.223.324.64.84.7-4.8-4.54.94.95.0-4.84.84.94.9
BMI without tail3.26.77.92.42.4-2.8-2.72.32.72.8-2.42.32.72.8
Body weight1.35.56.02.42.4-2.3-2.12.42.42.4-2.42.42.42.4
Epididymis fat weight0.20.50.8-0.9-0.90.2-0.1-0.8-0.7-0.60.8-0.8-0.7-0.6
Glucose1.72.63.51.61.5-1.6-1.41.61.61.8-1.61.61.91.6
Heart weight0.10.20.4-0.6-0.70.2-0.0-0.6-0.4-0.10.5-0.6-0.0-0.3
Left kidney weight0.10.20.6-0.2-0.20.80.7-0.2-0.4-0.60.2-0.2-0.5-0.5
Right kidney weight1.44.15.0-2.0-1.92.21.9-2.0-2.0-2.12.0-2.0-2.0-2.0
Tail length2.88.610.2-3.1-3.02.72.3-3.2-2.9-2.93.2-3.2-3.0-2.7
Length with tail2.17.68.6-2.7-2.52.92.8-2.7-2.7-2.92.7-2.7-2.8-2.7
Length without tail0.20.51.4-0.4-0.31.01.2-0.3-0.6-0.90.4-0.3-0.8-0.8
Liver weight, left2.64.15.51.91.8-2.3-2.32.02.02.0-2.02.01.92.1
Liver weight, right1.52.42.81.61.6-1.6-1.61.71.51.3-1.71.71.21.6
Parametrial fat weight0.30.50.8-0.8-0.70.60.6-0.9-0.6-0.60.9-0.9-0.6-0.6
Retroperitoneal fat weight0.31.01.40.90.9-1.2-1.20.91.01.0-0.90.90.91.0
Intraocular pressure0.20.31.20.1-0.0-0.7-1.10.00.40.8-0.0-0.00.90.5
Extensor digitorum longus weight5.421.623.54.64.6-4.8-4.64.54.84.7-4.54.54.74.8
Soleus weight9.427.529.95.55.4-5.1-4.55.45.45.1-5.45.45.15.3
Tibialis anterior weight1.24.34.72.12.1-2.1-1.82.12.22.0-2.12.11.92.1
Tibia length0.82.32.7-1.6-1.51.51.3-1.6-1.5-1.51.6-1.6-1.4-1.5
Number of licking bursts0.30.30.70.30.2-0.8-0.90.30.50.8-0.20.20.90.6
Food consumed during 24 hour testing period0.80.91.21.01.0-1.1-0.70.91.01.0-0.90.91.01.0
Times rat made contact with spout0.50.50.90.60.6-0.9-0.90.50.70.9-0.50.50.90.8
Mean time between licks in bursts3.75.27.0-2.5-2.62.11.7-2.5-2.4-2.02.5-2.5-2.0-2.3
Mean num. licks in bursts0.00.00.00.10.20.10.10.10.1-0.1-0.10.1-0.10.0
Std. dev. time between licks in bursts0.81.02.3-0.8-0.81.31.5-0.8-0.9-0.90.9-0.9-0.8-1.1
Water consumed over 24 hours0.50.51.10.91.1-0.40.00.90.70.5-0.90.90.60.6
Indifference point 0 sec0.10.20.20.50.4-0.4-0.10.50.40.4-0.50.50.40.3
Indifference point AUC0.70.81.0-1.0-1.00.90.6-1.0-0.9-0.80.9-1.0-0.7-0.9
Indifference point function ln k0.30.50.60.70.7-0.7-0.40.60.80.7-0.60.60.80.7
Indifference point function log k0.30.50.60.70.7-0.7-0.40.60.80.7-0.60.60.80.7
Delay discounting total patch changes 0 sec0.10.10.20.40.4-0.4-0.10.40.40.4-0.40.40.40.3
Delay discounting total patch changes 12 sec0.50.71.60.70.6-1.0-1.30.60.80.9-0.70.70.90.9
Delay discounting total patch changes 18 sec1.11.41.6-1.3-1.31.11.0-1.2-1.2-1.11.2-1.2-1.1-1.2
Delay discounting total patch changes 24 sec0.10.10.1-0.3-0.40.20.2-0.3-0.3-0.20.2-0.2-0.2-0.3
Delay discounting total patch changes 6 sec0.20.30.5-0.6-0.70.60.6-0.5-0.7-0.50.5-0.5-0.4-0.7
Delay discounting time to switch 0 sec0.40.61.31.01.0-0.6-0.41.10.70.1-1.11.1-0.10.6
Delay discounting water rate 0 sec0.30.51.60.30.4-0.8-0.80.20.71.1-0.20.11.20.8
Delay discounting water rate 12 sec2.23.35.41.51.5-2.0-2.01.51.82.3-1.41.42.31.9
Delay discounting water rate 18 sec0.60.82.20.10.1-1.2-1.50.00.71.40.0-0.11.40.9
Delay discounting water rate 24 sec1.62.34.60.90.9-1.8-2.10.81.52.0-0.80.82.11.7
Delay discounting water rate 6 sec0.10.10.3-0.3-0.3-0.3-0.5-0.40.00.50.4-0.40.60.2
Locomotor activity4.16.58.5-2.3-2.22.82.9-2.3-2.6-2.82.2-2.2-2.8-2.7
Locomotor testing distance2.33.94.6-1.8-1.82.12.1-1.9-2.0-2.11.8-1.8-2.1-2.0
Locomotor testing rearing0.00.00.1-0.0-0.1-0.1-0.2-0.10.10.30.1-0.10.30.1
Light reinforcement 17.213.114.8-3.6-3.73.63.1-3.6-3.7-3.83.5-3.5-3.8-3.6
Light reinforcement 22.73.54.0-1.8-1.92.01.8-1.8-1.9-2.01.8-1.8-1.9-1.9
Reaction time number correct1.21.72.81.11.0-1.6-1.51.01.41.7-0.90.91.71.4
Reaction time mean minus median0.40.60.9-0.8-0.81.00.7-0.8-0.7-0.60.9-0.9-0.4-0.7
Reaction time mean minus median AUC0.10.10.60.00.10.60.80.1-0.2-0.40.0-0.0-0.3-0.3
Reaction time num false alarms0.40.51.10.60.6-0.7-0.50.50.80.9-0.40.41.00.8
Reaction time num false alarms AUC0.50.81.50.70.6-1.0-0.80.60.91.2-0.50.51.21.0
Reaction time trials correct on left1.21.72.81.11.0-1.6-1.51.01.41.7-0.90.91.71.4
Reaction time trials on left1.21.72.81.11.1-1.6-1.41.01.41.6-0.90.91.71.4
Reaction time mean0.00.10.20.20.20.50.50.20.00.0-0.20.20.2-0.1
Reaction time mean AUC0.10.10.20.30.30.40.40.30.10.1-0.30.30.3-0.0
Median of all reaction times0.20.30.40.60.6-0.00.10.70.50.4-0.60.70.50.3
Reaction time omissions0.30.40.7-0.6-0.70.80.7-0.5-0.6-0.60.5-0.5-0.4-0.8
Reaction time false alarm rate0.00.00.10.30.2-0.20.00.20.30.2-0.20.20.30.3
Reaction time premature initiation rate0.71.01.6-1.1-1.30.80.5-1.1-1.0-0.61.2-1.2-0.5-0.9
Reaction time premature initiations0.20.30.6-0.7-0.80.1-0.2-0.7-0.40.20.8-0.80.3-0.3
Std. dev. reaction times0.10.20.7-0.3-0.30.80.6-0.3-0.4-0.30.4-0.4-0.1-0.5
Reaction time trials completed1.21.72.81.11.1-1.6-1.41.01.41.6-0.90.91.71.4
Reaction time trials AUC1.31.83.01.01.0-1.6-1.61.01.41.7-0.90.91.71.5
Social response proportion1.11.21.6-1.0-1.01.31.0-0.9-1.2-1.20.9-0.9-1.2-1.2
Social responses7.710.012.4-3.0-2.93.53.2-3.1-3.2-3.33.0-3.0-3.2-3.2
Social time0.50.60.90.70.7-0.9-0.90.80.70.7-0.90.90.60.7
Conditioned locomotion2.32.73.71.41.4-1.8-1.91.41.71.9-1.41.41.91.8
Cocaine response after cond. corrected7.58.410.72.72.8-3.0-3.02.63.13.2-2.62.63.33.1
Cocaine response after cond. not corrected7.88.710.92.82.8-3.0-3.12.63.13.3-2.62.63.33.2
Cocaine response before conditioning0.60.81.1-0.8-0.81.10.9-0.8-0.9-1.00.8-0.8-0.9-0.9
Saline control response0.10.10.20.20.2-0.5-0.40.30.30.5-0.30.30.50.3
Condit. Reinf. active minus inactive responses1.31.62.4-1.5-1.51.10.9-1.5-1.3-0.81.5-1.5-0.7-1.2
Condit. Reinf. active-inactive response ratio0.20.20.7-0.1-0.3-0.5-0.7-0.10.10.70.1-0.10.80.2
Condit. Reinf. active responses1.52.12.6-1.5-1.51.51.5-1.5-1.4-1.11.6-1.6-0.9-1.5
Condit. Reinf. inactive responses1.11.32.2-1.0-0.81.51.5-1.1-1.0-1.11.2-1.2-1.0-1.1
Condit. Reinf. lever presses1.62.23.0-1.7-1.71.41.1-1.7-1.5-1.21.7-1.7-1.1-1.4
Condit. Reinf. lever reinforcers received0.91.31.8-1.2-1.21.21.1-1.2-1.1-0.71.3-1.3-0.5-1.1
Pavlov. Cond. lever latency0.60.81.70.80.7-1.3-1.10.80.80.7-0.90.90.50.8
Pavlov. Cond. magazine entry latency0.40.50.8-0.6-0.60.90.8-0.7-0.6-0.70.7-0.7-0.6-0.6
Pavlov. Cond. change in total contacts0.40.61.1-0.8-0.81.10.9-0.8-0.7-0.50.8-0.8-0.3-0.8
Pavlov. Cond. index score0.60.81.5-0.8-0.81.21.0-0.9-0.8-0.70.9-0.9-0.5-0.8
Pavlov. Cond. latency score0.60.81.6-0.8-0.81.31.1-0.8-0.8-0.80.9-0.9-0.6-0.9
Pavlov. Cond. lever contacts0.40.61.1-0.8-0.71.00.8-0.8-0.7-0.50.9-0.9-0.3-0.7
Pavlov. Cond. magazine entry number0.70.81.30.80.8-1.1-1.10.90.80.9-0.90.90.80.9
Pavlov. Cond. intertrial magazine entries0.50.71.10.70.7-1.0-1.00.70.81.0-0.70.61.00.9
Pavlov. Cond. lever-magazine prob. diff.0.70.91.7-0.9-0.91.31.1-0.9-0.9-0.80.9-1.0-0.7-0.9
Pavlov. Cond. response bias1.21.62.3-1.3-1.31.51.2-1.4-1.2-1.01.4-1.4-0.8-1.2
Conditioned reinforcement - actives2.22.22.5-1.5-1.41.51.4-1.6-1.4-1.61.5-1.5-1.5-1.4
Conditioned reinforcement - inactives0.60.71.10.70.8-0.9-1.10.71.00.9-0.70.70.81.0
Conditioned locomotion7.18.59.4-3.0-3.02.92.5-3.1-2.9-3.03.0-3.0-2.9-2.9
Intermittent access intake day 1-15 change6.16.07.2-2.6-2.52.32.1-2.7-2.5-2.32.6-2.6-2.3-2.4
Intermittent access intake escalation4.74.76.4-2.4-2.41.81.4-2.5-2.2-1.82.5-2.5-1.9-2.0
Intermittent access intake escalation 26.05.97.9-2.7-2.72.31.6-2.8-2.5-2.12.8-2.8-2.1-2.2
Intermitt. access day 1 inactive lever presses0.00.00.1-0.2-0.1-0.1-0.2-0.30.00.10.3-0.30.10.1
Intermitt. access day 15 inactive lever presses0.40.40.6-0.7-0.70.60.4-0.8-0.6-0.60.8-0.8-0.6-0.6
Intermitt. access escalation Index0.10.10.20.40.40.10.50.40.1-0.0-0.40.40.0-0.0
Intermittent access day 1 total infusions0.00.00.10.20.3-0.1-0.10.20.20.1-0.20.20.00.2
Intermittent access day 15 total infusions1.61.72.4-1.5-1.41.20.9-1.5-1.3-1.21.5-1.5-1.2-1.2
Intermittent access terminal intake (last 3 days)0.91.01.3-1.1-0.91.00.8-1.1-0.9-1.01.1-1.1-1.1-0.9
Intermittent access total infusions0.10.20.3-0.4-0.40.30.2-0.5-0.3-0.40.5-0.5-0.4-0.3
Intermittent access day 1 locomotion0.40.40.5-0.7-0.60.60.4-0.7-0.6-0.60.7-0.7-0.6-0.5
Intermittent access day 15 total locomotion3.63.84.4-2.1-2.01.81.4-2.1-2.0-1.92.1-2.1-2.0-1.9
Intermittent access total locomotion1.01.11.3-1.1-1.01.10.9-1.1-1.0-1.11.1-1.1-1.2-1.0
Intermittent access standard deviation2.02.22.8-1.6-1.61.51.0-1.7-1.4-1.31.7-1.7-1.2-1.3
Cocaine induced anxiety1.01.21.8-0.9-0.81.41.3-0.9-1.0-1.30.8-0.8-1.3-1.2
Post-drug Anxiety1.01.11.9-0.8-0.81.41.2-0.7-1.0-1.30.8-0.7-1.3-1.1
Baseline Anxiety0.10.10.2-0.3-0.40.1-0.3-0.3-0.20.00.4-0.40.0-0.1
Lifetime Intake0.10.10.1-0.3-0.20.20.1-0.3-0.2-0.30.3-0.3-0.3-0.2
Incentive Sensitization - Responses0.00.00.1-0.2-0.1-0.1-0.2-0.3-0.00.10.2-0.20.00.1
Incentive Sensitization - Breakpoint0.10.10.1-0.3-0.20.0-0.1-0.4-0.2-0.10.3-0.3-0.1-0.1
Progressive ratio test 1 active lever presses0.10.20.30.30.3-0.5-0.50.20.40.5-0.20.20.40.5
Progressive ratio test 1 breakpoint0.20.20.40.40.4-0.6-0.60.40.50.5-0.30.30.50.5
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.10.10.1-0.2-0.1-0.30.2-0.2-0.3-0.1
Progressive ratio test 2 active lever presses0.00.00.1-0.3-0.20.0-0.1-0.3-0.1-0.00.3-0.3-0.0-0.0
Progressive ratio test 2 breakpoint0.10.10.2-0.4-0.30.30.2-0.5-0.3-0.30.5-0.5-0.3-0.3
Progressive ratio test 2 inactive lever presses0.10.10.2-0.2-0.20.30.2-0.3-0.2-0.40.2-0.2-0.5-0.2
Total sessions with >9 infusions0.00.00.10.20.30.10.30.10.1-0.1-0.10.2-0.1-0.0
Short access day 1 total inactive lever presses0.10.10.3-0.4-0.30.30.1-0.4-0.3-0.50.3-0.3-0.5-0.3
Short access day 10 total inactive lever presses0.00.00.10.00.0-0.0-0.3-0.10.10.1-0.00.00.10.1
Short access day 1 total infusions0.40.50.9-0.5-0.40.80.8-0.5-0.6-1.00.5-0.5-1.0-0.7
Short access day 10 total infusions0.00.00.0-0.1-0.0-0.1-0.1-0.10.10.00.2-0.20.00.1
Short access total infusions0.00.00.00.00.10.10.1-0.00.0-0.2-0.00.0-0.2-0.0
Short access day 1 locomotion1.41.52.0-1.1-0.91.41.4-1.1-1.1-1.41.1-1.1-1.4-1.2
Short access day 10 total locomotion3.33.64.5-2.0-2.01.81.6-2.1-1.8-1.82.1-2.1-1.7-1.8
Short access total locomotion0.90.91.2-0.9-0.81.11.0-1.0-0.9-1.10.9-0.9-1.0-0.9
Compulsive drug intake1.01.01.51.21.1-0.8-0.61.21.00.8-1.21.20.90.9
One hour access (0.3 mA shock)0.20.20.30.40.5-0.4-0.50.40.50.4-0.40.40.40.5
One hour access (shock baseline)0.00.00.1-0.2-0.10.0-0.1-0.30.00.10.3-0.30.10.0
Number of responses in last shaping day0.10.10.2-0.3-0.20.20.4-0.4-0.2-0.40.4-0.4-0.4-0.2
Context. condit. distance diff. score0.30.30.50.50.6-0.7-0.60.50.70.4-0.50.50.30.7
Locomotion velocity, session 11.01.11.9-0.8-0.81.41.3-0.8-1.0-1.30.8-0.8-1.2-1.2
Locomotion distance, session 10.91.13.3-0.7-0.51.21.2-0.6-1.0-1.60.5-0.5-1.8-1.1
Locomotion velocity, session 26.07.110.7-2.4-2.22.92.7-2.3-2.7-3.22.3-2.3-3.3-2.8
Locomotion distance, session 22.94.16.0-1.7-1.72.42.3-1.6-2.1-2.41.5-1.5-2.4-2.3
Locomotion velocity, session 36.17.18.2-2.8-2.82.52.2-2.8-2.7-2.52.9-2.9-2.5-2.6
Locomotion distance, session 30.00.00.00.10.1-0.1-0.20.00.20.2-0.00.00.20.2
Stereotopy head waving bouts, day 35.97.08.1-2.7-2.72.42.4-2.6-2.8-2.72.7-2.6-2.8-2.7
Stereotopy head waving duration, day 36.67.98.5-2.9-2.92.62.5-2.8-2.9-2.82.9-2.9-2.9-2.9
Locomotion velocity, session 70.60.61.3-0.6-0.41.11.1-0.8-0.6-0.90.8-0.8-0.8-0.6
Locomotion distance, session 70.30.40.70.60.6-0.5-0.70.50.70.7-0.40.40.80.8
Stereotopy head waving bouts, day 70.20.20.6-0.2-0.20.50.8-0.1-0.4-0.70.2-0.2-0.7-0.5
Stereotopy head waving duration, day 70.60.71.6-0.6-0.60.91.3-0.5-0.8-1.00.5-0.5-1.0-0.9
Locomotion velocity, session 81.41.62.9-1.0-0.81.51.7-0.9-1.3-1.60.9-0.9-1.7-1.4
Locomotion distance, session 80.40.51.4-0.6-0.50.60.6-0.6-0.7-1.00.6-0.6-1.2-0.7
Degree of sensitization distance0.40.40.60.70.8-0.5-0.50.60.60.5-0.70.70.40.7
Degree of sensitization stereotypy1.41.52.11.41.5-0.9-0.61.41.31.0-1.41.41.01.1
Condit. Reinf. active minus inactive responses4.75.35.9-2.4-2.32.11.9-2.4-2.3-2.32.4-2.4-2.4-2.3
Condit. Reinf. active-inactive response ratio1.71.92.6-1.6-1.51.20.9-1.6-1.4-1.21.6-1.6-1.1-1.3
Condit. Reinf. active responses4.96.07.7-2.4-2.32.32.3-2.4-2.5-2.72.3-2.3-2.8-2.5
Condit. Reinf. inactive responses1.61.93.3-1.2-1.21.41.5-1.1-1.5-1.71.1-1.1-1.8-1.5
Incentive salience index mean3.13.85.1-1.9-1.81.81.8-1.9-2.0-2.11.9-1.9-2.3-2.0
Condit. Reinf. lever presses0.40.51.5-0.3-0.30.71.1-0.2-0.7-1.10.2-0.2-1.2-0.8
Time in familiar zone, hab. session 11.91.82.5-1.5-1.51.11.0-1.5-1.3-1.21.6-1.6-1.3-1.2
Time in novel zone, hab. session 10.80.71.31.01.1-0.4-0.11.10.90.6-1.11.10.70.7
Total zone transitions, hab. session 11.72.43.5-1.3-1.31.81.7-1.2-1.6-1.91.2-1.2-1.9-1.7
Total locomotion distance, hab. session 12.33.35.5-1.4-1.22.22.3-1.3-1.8-2.31.3-1.3-2.4-1.9
Locomotion velocity, hab. session 12.84.16.5-1.7-1.62.32.2-1.6-2.1-2.51.6-1.6-2.6-2.1
Time in familiar zone, hab. session 25.45.67.4-2.6-2.71.91.6-2.7-2.4-2.12.7-2.7-2.1-2.2
Time in novel zone, hab. session 24.04.05.52.32.3-1.5-1.12.32.01.7-2.32.31.81.8
Total zone transitions, hab. session 20.20.30.80.00.10.70.70.2-0.4-0.8-0.20.3-0.9-0.6
Total locomotion distance, hab. session 22.02.74.6-1.4-1.41.81.6-1.3-1.7-2.01.3-1.3-2.1-1.7
Locomotion velocity, hab. session 22.22.95.3-1.5-1.41.91.7-1.3-1.8-2.21.3-1.2-2.3-1.9
Novel to familiar place preference ratio3.23.34.72.12.2-1.4-0.92.11.81.5-2.22.21.61.6
Novelty place preference1.81.92.81.61.7-0.9-0.61.61.41.1-1.71.71.11.2
Time in novel zone, NPP test2.12.33.41.71.8-1.1-0.71.81.51.2-1.81.81.21.4
Total zone transitions, NPP test0.20.30.8-0.3-0.30.60.4-0.2-0.6-0.80.1-0.1-0.9-0.6
Total locomotion distance, NPP test0.20.30.8-0.2-0.10.70.6-0.1-0.5-0.80.0-0.0-0.9-0.5
Locomotion velocity, NPP test0.40.51.2-0.5-0.40.90.8-0.4-0.8-1.10.3-0.3-1.1-0.8
Pavlov. Cond. lever latency0.20.20.90.1-0.0-0.4-0.70.10.40.8-0.10.11.00.4
Pavlov. Cond. magazine entry latency3.34.35.2-2.2-2.21.61.4-2.2-2.1-2.12.2-2.2-2.3-1.9
Pavlov. Cond. change in total contacts0.20.20.6-0.4-0.30.20.3-0.4-0.4-0.60.4-0.4-0.8-0.3
Pavlov. Cond. index score0.91.12.5-1.0-0.80.91.0-1.0-1.1-1.40.9-0.9-1.6-1.0
Pavlov. Cond. latency score1.01.33.1-0.9-0.81.01.2-0.9-1.1-1.50.9-0.9-1.7-1.1
Pavlov. Cond. lever contacts0.40.51.5-0.4-0.20.61.0-0.3-0.6-1.10.3-0.3-1.2-0.7
Pavlov. Cond. magazine entry number1.01.21.91.21.1-0.8-0.71.21.11.2-1.21.21.41.0
Pavlov. Cond. intertrial magazine entries0.00.10.1-0.3-0.3-0.1-0.3-0.3-0.10.20.3-0.30.2-0.0
Pavlov. Cond. lever-magazine prob. diff.1.41.73.2-1.2-1.11.11.2-1.2-1.3-1.61.2-1.2-1.8-1.2
Pavlov. Cond. response bias1.51.82.7-1.4-1.31.11.0-1.4-1.4-1.51.4-1.4-1.6-1.3
Bone: apparent density0.30.52.20.00.00.91.50.1-0.5-1.0-0.10.1-1.0-0.7
Bone surface1.32.37.1-0.6-0.61.92.7-0.6-1.3-2.00.5-0.5-2.0-1.6
Bone volume1.22.17.3-0.5-0.51.92.7-0.5-1.2-1.90.4-0.4-1.9-1.6
Bone: connectivity density0.10.20.50.40.40.30.70.50.0-0.4-0.50.5-0.5-0.1
Bone: cortical apparent density0.91.21.51.11.0-1.0-0.91.11.01.2-1.11.11.21.0
Bone: cortical area0.30.51.01.01.0-0.20.21.00.70.4-0.90.90.40.5
Bone: cortical porosity0.80.81.4-0.8-0.71.11.2-0.7-0.9-1.00.7-0.7-1.0-1.0
Bone: cortical porosity0.30.30.9-0.2-0.20.81.0-0.2-0.5-0.70.1-0.1-0.7-0.6
Bone: cortical thickness0.91.52.11.41.4-0.9-0.71.41.21.0-1.41.41.11.1
Bone: cortical thickness0.10.20.50.20.2-0.4-0.50.20.40.6-0.10.10.70.5
Bone: cortical tissue density0.60.81.10.90.8-0.9-0.80.90.91.0-0.90.91.10.8
Bone: elastic displacement0.20.20.4-0.4-0.40.70.7-0.4-0.5-0.40.4-0.4-0.3-0.6
Bone: elastic work0.20.30.70.60.8-0.10.10.60.60.4-0.60.60.50.4
Bone: endosteal estimation0.10.30.70.60.8-0.4-0.10.60.60.4-0.60.60.40.4
Bone: endosteal perimeter0.40.91.7-0.7-0.71.11.3-0.7-0.8-1.10.7-0.7-1.1-0.9
Bone: final force1.11.73.11.61.8-0.7-0.41.61.41.0-1.51.51.11.2
Bone: final moment0.81.42.51.41.6-0.6-0.31.41.20.9-1.31.31.01.0
Bone: marrow area0.10.30.60.60.8-0.4-0.10.70.60.4-0.60.60.40.5
Bone: maximum diameter1.12.03.6-1.1-1.11.71.9-1.1-1.4-1.71.1-1.1-1.6-1.5
Bone: maximum force1.12.03.41.61.8-0.9-0.61.61.51.2-1.51.61.31.3
Bone: maximum moment0.91.62.71.51.7-0.7-0.51.41.41.1-1.41.41.21.1
Bone: minimum diameter0.00.10.40.10.20.20.60.1-0.0-0.3-0.10.1-0.2-0.1
Bone: periosteal estimation0.20.40.90.80.9-0.10.30.80.60.2-0.70.80.20.4
Bone: periosteal perimeter0.20.41.4-0.2-0.20.91.2-0.2-0.4-0.80.2-0.2-0.7-0.6
Bone: post-yield work0.60.91.11.01.0-0.8-0.80.91.00.9-0.90.90.91.0
Bone: stiffness2.64.25.52.32.3-1.7-1.42.32.21.8-2.22.21.82.0
Bone: tissue strength1.51.51.91.31.3-1.0-0.91.31.21.1-1.41.41.11.1
Bone: trabecular number1.32.03.4-1.0-1.01.71.8-1.1-1.3-1.81.0-1.0-1.8-1.5
Bone: trabecular spacing1.62.14.40.90.8-1.8-2.10.81.41.9-0.80.81.91.6
Bone: trabecular thickness0.91.14.6-0.0-0.01.42.10.0-0.7-1.4-0.10.1-1.4-1.1
Bone: trabecular tissue density2.02.73.61.51.5-1.9-1.91.61.61.7-1.61.61.61.7
Breakpoint value in progressive ratio session4.85.36.7-2.5-2.61.91.7-2.6-2.3-2.12.6-2.6-2.1-2.2
Distance traveled before self-admin0.40.40.60.70.8-0.5-0.30.70.60.4-0.80.80.40.5
Distance traveled after self-admin0.70.81.2-0.8-0.80.90.9-0.8-0.9-1.00.8-0.8-1.1-0.9
Delta time in closed arm before/after self-admin2.12.14.01.00.9-1.8-2.00.91.41.8-0.90.91.81.6
Delta time in open arm before/after self-admin0.90.81.21.01.1-0.6-0.71.10.90.8-1.11.10.80.8
Diff in mean of infusions in LGA sessions2.02.22.6-1.6-1.61.31.2-1.6-1.6-1.41.6-1.6-1.4-1.5
Extinction: sum of active levers before priming0.80.81.3-1.1-1.10.40.2-1.1-0.9-0.71.1-1.1-0.8-0.7
Active lever presses in extinction session 62.82.72.9-1.6-1.61.61.6-1.7-1.7-1.61.6-1.6-1.7-1.6
Delta distance traveled before/after self-admin1.92.12.2-1.5-1.41.51.3-1.5-1.5-1.41.5-1.5-1.5-1.4
Delta ambulatory time before/after self-admin2.22.42.6-1.5-1.51.61.4-1.6-1.6-1.61.5-1.5-1.6-1.5
Time in closed arm before self-admin0.30.30.70.70.7-0.10.00.80.40.1-0.80.80.10.3
Time in closed arm after self-admin0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.10.00.1-0.10.1-0.0
Time in open arm before self-admin0.50.50.8-0.8-0.80.50.6-0.9-0.7-0.60.8-0.9-0.7-0.7
Time in open arm after self-admin0.80.91.01.01.0-0.9-0.81.01.01.0-1.01.01.00.9
Sum of active levers in priming session hrs 5-60.00.00.0-0.00.0-0.0-0.0-0.1-0.0-0.1-0.00.0-0.20.0
Time to tail flick, vehicle, before self-admin0.90.91.3-0.7-0.71.11.1-0.7-1.0-1.20.7-0.7-1.2-1.0
Time to tail flick, vehicle, after self-admin0.10.10.2-0.3-0.4-0.2-0.5-0.4-0.10.00.4-0.40.00.1
Time to tail flick, test, before self-admin0.50.51.2-0.5-0.40.91.1-0.5-0.6-0.80.5-0.4-0.8-0.8
Time to tail flick, test, after self-admin0.40.40.6-0.6-0.60.70.7-0.5-0.7-0.70.6-0.6-0.7-0.8
Delta time to tail flick, vehicle, before/after SA0.90.92.10.60.6-1.3-1.40.60.91.1-0.60.51.01.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.4-0.30.0-0.3-0.3-0.2-0.00.4-0.40.0-0.1
Ambulatory time before self-admin0.30.40.50.70.7-0.5-0.30.70.60.5-0.70.70.50.5
Ambulatory time after self-admin0.40.40.8-0.6-0.60.70.7-0.6-0.6-0.80.6-0.6-0.9-0.6
Total heroin consumption2.02.42.6-1.6-1.61.31.4-1.6-1.6-1.51.6-1.6-1.6-1.5
Area under the delay curve2.32.53.01.71.7-1.5-1.01.71.71.5-1.61.61.61.5
Delay disc. indifference point, 0s delay4.85.37.82.72.7-1.9-1.32.72.31.8-2.82.81.72.0
Delay disc. indifference point, 16s delay0.10.10.20.40.3-0.5-0.20.40.40.4-0.30.30.40.3
Delay disc. indifference point, 2s delay5.05.66.92.62.6-2.2-1.62.62.52.1-2.62.62.02.3
Delay disc. indifference point, 24s delay1.01.01.41.00.9-1.0-0.90.91.01.1-1.01.01.21.0
Delay disc. indifference point, 4s delay0.80.81.11.11.1-1.0-0.31.11.00.8-1.01.00.80.8
Delay disc. indifference point, 8s delay1.81.82.21.31.4-1.3-1.21.31.51.4-1.31.31.51.4
Delay discount exponential model param2.32.42.8-1.7-1.71.51.0-1.6-1.7-1.51.6-1.6-1.6-1.5
Delay discount hyperbolic model param3.03.23.8-1.9-1.91.71.2-1.9-1.9-1.81.9-1.9-1.8-1.8
Fecal boli incidents, locomotor time 11.92.13.21.41.5-1.2-1.81.41.41.3-1.51.41.31.6
Change in fecal boli incidents, locomotor task0.20.21.5-0.2-0.10.41.2-0.3-0.3-0.40.3-0.3-0.3-0.4
Time >=10cm from walls, locomotor time 10.30.30.70.70.80.10.10.70.50.2-0.80.80.30.4
Bouts of movement, locomotor time 10.10.10.2-0.4-0.20.40.2-0.4-0.3-0.40.4-0.4-0.4-0.3
Total resting periods, locomotor time 10.20.30.3-0.5-0.40.60.5-0.5-0.5-0.50.6-0.6-0.6-0.4
Rest time, locomotor task time 10.40.51.0-0.6-0.50.50.6-0.6-0.7-0.90.6-0.6-1.0-0.6
Distance moved, locomotor task time 10.40.40.70.80.8-0.30.20.80.50.5-0.80.80.50.4
Vertical activity count, locomotor time 10.50.51.50.60.6-0.6-0.30.60.71.0-0.60.61.20.7
Time >=10cm from walls, locomotor time 21.92.02.31.51.5-1.1-1.21.41.51.5-1.41.41.51.5
Bouts of movement, locomotor time 21.01.11.7-0.9-0.91.31.1-0.8-1.0-1.30.8-0.8-1.3-1.2
Total resting periods, locomotor time 21.01.11.7-0.8-0.81.31.2-0.7-1.0-1.30.8-0.7-1.3-1.1
Rest time, locomotor task time 20.91.01.5-0.9-0.81.21.1-0.9-1.0-1.20.9-0.8-1.2-1.1
Distance moved, locomotor task time 21.01.11.61.00.9-1.3-1.21.01.01.1-1.01.01.11.1
Vertical activity count, locomotor time 21.31.42.11.01.0-1.4-1.41.01.21.3-1.00.91.31.3
Weight adjusted by age0.80.91.70.80.8-1.0-1.10.71.01.2-0.70.71.31.1
Seeking ratio, delayed vs. immediate footshock4.85.55.9-2.3-2.32.32.4-2.3-2.4-2.42.3-2.3-2.3-2.4
Locomotion in novel chamber0.10.10.3-0.4-0.50.1-0.1-0.4-0.3-0.00.4-0.40.0-0.3
Locomotion in novel chamber post-restriction0.70.81.1-0.9-1.00.60.8-1.0-0.8-0.81.1-1.1-0.8-0.8
Progressive ratio0.20.31.00.30.4-0.7-1.00.40.40.5-0.40.40.20.5
Food seeking constrained by brief footshock0.50.61.6-0.8-0.70.50.1-0.7-0.8-1.00.7-0.7-1.3-0.7
Seeking ratio, punishment vs. effort0.40.50.9-0.6-0.60.80.8-0.6-0.7-0.90.6-0.6-0.9-0.7
Run reversals in cocaine runway, females0.50.50.7-0.6-0.50.70.8-0.7-0.7-0.70.7-0.7-0.9-0.7
Run reversals in cocaine runway, males1.91.82.2-1.3-1.31.11.2-1.3-1.4-1.41.3-1.3-1.5-1.4
Latency to leave start box in cocaine runway1.11.22.9-0.8-1.01.41.7-0.7-1.1-1.10.8-0.7-1.0-1.3
Latency to leave start box in cocaine runway, F0.20.21.20.20.10.71.10.3-0.2-0.4-0.30.3-0.3-0.5
Latency to leave start box in cocaine runway, M1.81.82.8-1.6-1.71.00.8-1.5-1.3-1.01.6-1.6-0.9-1.2
Cd content in liver0.20.30.40.60.5-0.2-0.20.60.50.5-0.60.60.60.4
Co content in liver0.40.50.7-0.8-0.80.70.5-0.8-0.8-0.70.8-0.8-0.7-0.7
Cu content in liver0.10.10.20.30.40.50.50.30.0-0.3-0.30.3-0.3-0.1
Fe content in liver0.00.00.1-0.2-0.10.0-0.3-0.2-0.1-0.10.2-0.2-0.20.0
K content in liver0.10.10.4-0.0-0.10.50.6-0.0-0.3-0.6-0.00.0-0.7-0.4
Mg content in liver0.10.10.50.0-0.00.50.70.1-0.3-0.5-0.10.1-0.5-0.4
Mn content in liver2.32.65.4-1.1-0.92.12.3-1.1-1.5-2.11.1-1.1-2.1-1.7
Na content in liver0.40.50.90.90.9-0.4-0.30.90.60.1-0.91.00.10.6
Rb content in liver0.20.20.40.60.60.10.30.60.3-0.0-0.60.6-0.00.1
Se content in liver0.30.41.0-0.6-0.40.60.5-0.6-0.6-0.90.6-0.6-1.0-0.5
Sr content in liver0.10.10.40.0-0.0-0.4-0.6-0.00.20.30.0-0.00.40.3
Zn content in liver0.91.02.0-1.3-1.40.40.0-1.3-0.9-0.41.3-1.3-0.4-0.7