Hub : Genes

Zzef1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024535 0.05 0.04 3.3e-04 0.03 0.03 0.02 0.03 6.7e-04 6.4e-04 1.0e-03 4.3e-04
2 Adipose mRNA stability ENSRNOG00000024535 0.04 0.03 2.5e-03 0 0.01 0.01 0.01 1.5e-01 1.8e-02 5.7e-02 2.8e-02
3 BLA gene expression ENSRNOG00000024535 0.16 0.1 2.5e-06 0.11 0.1 0.1 0.1 1.1e-06 9.4e-06 8.4e-06 4.0e-06
4 Brain gene expression ENSRNOG00000024535 0.44 0.18 0.0e+00 0.36 0.37 0.38 0.37 7.0e-35 2.5e-36 1.9e-36 3.2e-36
5 Brain intron excision ratio chr10:57495438:57498677 0.03 0.03 1.0e-02 -0 -0 0 0 3.8e-01 3.9e-01 1.8e-01 1.9e-01
6 Brain mRNA stability ENSRNOG00000024535 0.03 0.02 7.3e-03 0.02 0.01 0.01 0.01 2.3e-03 2.4e-02 6.5e-02 1.6e-02
7 NAcc gene expression ENSRNOG00000024535 0.05 0.04 2.2e-03 0.03 0.03 0.03 0.03 5.4e-03 2.1e-03 2.2e-03 3.1e-03
8 NAcc intron excision ratio chr10:57488934:57491363 0.06 0.05 1.5e-03 0.01 0.02 0.02 0.01 8.9e-02 1.1e-02 7.3e-03 3.7e-02
9 PL gene expression ENSRNOG00000024535 0.23 0.12 8.4e-15 0.13 0.17 0.18 0.17 2.6e-10 4.2e-13 1.9e-13 4.6e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.20.60.9-0.7-0.11.00.9-0.9-0.60.90.40.9
BMI without tail0.40.81.5-1.1-0.31.01.1-1.2-0.51.10.21.0
Body weight0.83.39.5-3.1-2.21.51.1-3.00.80.9-0.80.7
Epididymis fat weight2.86.610.2-2.5-0.23.13.2-2.9-1.73.21.83.0
Glucose1.11.74.92.21.9-0.9-0.51.9-0.9-0.31.0-0.1
Heart weight0.81.11.9-0.80.21.21.3-0.7-0.91.41.01.3
Left kidney weight0.20.51.30.50.90.20.6-0.0-0.80.71.10.7
Right kidney weight0.10.31.30.30.70.10.40.0-0.60.51.20.4
Tail length1.54.412.6-3.4-2.41.81.5-3.50.71.4-0.91.1
Length with tail0.93.39.1-3.0-2.51.10.7-3.01.30.6-1.20.3
Length without tail0.61.33.9-2.0-1.51.10.7-1.80.60.6-0.40.3
Liver weight, left0.40.61.6-1.3-1.30.3-0.1-1.00.8-0.1-0.8-0.2
Liver weight, right0.61.02.1-1.5-0.61.31.1-0.9-0.31.10.31.0
Parametrial fat weight8.316.227.4-3.8-0.65.25.0-4.3-2.64.92.74.6
Retroperitoneal fat weight0.20.61.00.71.00.60.80.5-1.00.80.80.8
Intraocular pressure1.82.65.91.52.10.91.30.6-2.01.42.41.4
Extensor digitorum longus weight2.710.918.0-1.31.44.24.2-1.1-3.44.23.24.2
Soleus weight1.85.211.3-3.4-1.83.02.5-2.7-0.42.30.32.0
Tibialis anterior weight2.58.616.3-2.40.04.03.8-2.1-2.33.81.93.6
Tibia length0.82.34.9-1.7-2.2-0.5-0.9-1.81.9-1.0-1.6-1.1
Number of licking bursts0.20.20.40.3-0.0-0.6-0.60.40.4-0.6-0.4-0.6
Food consumed during 24 hour testing period0.70.81.5-0.6-1.1-0.6-0.9-0.51.1-0.9-1.2-1.0
Times rat made contact with spout1.21.32.0-0.2-1.0-1.3-1.3-0.51.3-1.3-1.4-1.4
Mean time between licks in bursts1.11.53.1-1.2-0.21.81.6-1.0-0.81.50.91.4
Mean num. licks in bursts0.10.10.4-0.4-0.5-0.1-0.1-0.70.4-0.2-0.4-0.2
Std. dev. time between licks in bursts0.40.40.9-0.6-0.01.00.8-0.3-0.40.80.60.8
Water consumed over 24 hours3.84.57.3-0.8-2.1-2.0-2.3-0.82.6-2.3-2.7-2.5
Indifference point 0 sec1.52.43.1-0.6-1.5-1.7-1.6-1.21.7-1.7-1.8-1.7
Indifference point AUC2.32.76.71.12.00.71.40.2-2.11.52.61.6
Indifference point function ln k5.78.114.1-0.9-2.8-2.5-3.1-0.23.6-3.2-3.7-3.3
Indifference point function log k5.78.114.1-0.9-2.8-2.5-3.1-0.23.6-3.2-3.7-3.3
Delay discounting total patch changes 0 sec1.01.62.2-0.5-1.2-1.4-1.3-1.11.4-1.4-1.5-1.4
Delay discounting total patch changes 12 sec1.01.42.80.01.00.81.3-0.4-1.51.31.71.4
Delay discounting total patch changes 18 sec0.50.71.10.10.70.41.0-1.0-1.11.00.91.0
Delay discounting total patch changes 24 sec0.60.72.10.51.10.00.6-0.1-1.20.71.50.7
Delay discounting total patch changes 6 sec1.32.04.20.71.70.61.30.0-2.01.42.01.5
Delay discounting time to switch 0 sec1.11.72.9-0.40.61.71.70.0-1.51.71.01.7
Delay discounting water rate 0 sec0.61.01.60.7-0.1-1.1-1.21.00.8-1.2-0.8-1.2
Delay discounting water rate 12 sec0.20.30.8-0.6-0.30.90.6-0.4-0.00.5-0.10.4
Delay discounting water rate 18 sec0.81.12.4-1.1-1.5-0.1-0.6-1.01.5-0.7-1.3-0.9
Delay discounting water rate 24 sec0.20.21.80.30.20.50.11.40.00.00.00.0
Delay discounting water rate 6 sec0.40.62.60.5-0.0-0.3-0.71.60.5-0.8-0.4-0.7
Locomotor activity0.50.81.5-0.40.31.21.10.2-0.81.10.91.1
Locomotor testing distance2.64.26.60.01.52.52.50.7-2.42.52.22.6
Locomotor testing rearing3.45.38.70.52.02.22.60.2-2.82.72.92.8
Light reinforcement 11.22.23.8-0.01.11.61.8-0.7-1.71.81.91.8
Light reinforcement 20.20.30.80.50.70.30.40.1-0.60.40.90.4
Reaction time number correct0.20.30.8-0.5-0.50.6-0.00.90.4-0.1-0.8-0.1
Reaction time mean minus median0.40.51.31.00.4-1.1-0.80.50.2-0.8-0.1-0.8
Reaction time mean minus median AUC0.10.10.40.60.4-0.5-0.30.10.1-0.20.1-0.3
Reaction time num false alarms0.71.02.01.0-0.0-1.4-1.30.10.7-1.3-0.8-1.3
Reaction time num false alarms AUC0.60.81.51.00.1-1.2-1.10.40.5-1.2-0.6-1.1
Reaction time trials correct on left0.20.30.8-0.5-0.50.6-0.00.90.4-0.1-0.8-0.1
Reaction time trials on left0.20.30.8-0.5-0.50.60.00.90.3-0.0-0.7-0.1
Reaction time mean0.20.20.60.70.2-0.8-0.5-0.00.3-0.5-0.1-0.6
Reaction time mean AUC0.40.51.21.00.4-1.1-0.80.30.3-0.7-0.1-0.8
Median of all reaction times0.10.10.30.60.3-0.5-0.2-0.00.1-0.20.0-0.3
Reaction time omissions0.40.51.30.20.70.60.70.1-0.80.81.10.7
Reaction time false alarm rate0.40.61.61.00.3-1.3-1.0-0.20.3-1.0-0.2-0.9
Reaction time premature initiation rate1.92.55.4-0.8-1.7-1.2-1.6-0.02.0-1.7-2.3-1.8
Reaction time premature initiations1.72.45.7-1.0-1.8-0.8-1.50.31.9-1.5-2.4-1.6
Std. dev. reaction times0.81.22.61.10.1-1.6-1.40.50.8-1.3-0.5-1.4
Reaction time trials completed0.20.30.8-0.5-0.50.60.00.90.3-0.0-0.7-0.1
Reaction time trials AUC0.20.20.7-0.5-0.50.5-0.00.80.3-0.1-0.8-0.1
Social response proportion3.03.38.0-2.5-2.8-0.1-0.9-1.52.3-1.0-2.1-1.2
Social responses1.52.03.8-1.9-0.81.81.5-2.0-0.41.50.71.3
Social time0.81.12.6-1.6-0.91.51.0-1.1-0.01.00.00.8
Conditioned locomotion0.60.81.41.20.5-1.1-1.01.20.3-0.9-0.3-0.8
Cocaine response after cond. corrected0.70.81.4-0.9-1.2-0.6-0.7-0.91.1-0.8-0.9-0.9
Cocaine response after cond. not corrected0.50.51.1-0.9-1.0-0.3-0.4-1.00.8-0.4-0.7-0.5
Cocaine response before conditioning0.60.71.2-0.40.31.01.1-0.4-0.81.10.71.1
Saline control response0.40.50.8-0.50.20.80.9-0.6-0.60.90.70.9
Condit. Reinf. active minus inactive responses0.70.81.5-0.7-1.2-0.6-0.9-0.41.2-0.9-1.0-1.0
Condit. Reinf. active-inactive response ratio0.90.91.5-0.4-1.0-0.9-1.0-0.31.2-1.1-1.1-1.1
Condit. Reinf. active responses0.30.40.7-0.6-0.8-0.3-0.6-0.30.9-0.6-0.6-0.7
Condit. Reinf. inactive responses0.10.20.40.30.50.40.30.6-0.40.30.60.3
Condit. Reinf. lever presses0.30.41.10.90.5-0.7-0.61.10.1-0.60.1-0.5
Condit. Reinf. lever reinforcers received0.20.30.5-0.4-0.6-0.3-0.5-0.10.7-0.6-0.4-0.6
Pavlov. Cond. lever latency1.21.62.9-1.4-0.41.71.6-1.3-0.71.50.31.4
Pavlov. Cond. magazine entry latency0.80.91.50.5-0.3-1.2-1.20.61.0-1.2-0.8-1.2
Pavlov. Cond. change in total contacts0.50.81.40.7-0.1-1.2-1.10.50.7-1.1-0.5-1.1
Pavlov. Cond. index score0.91.12.41.50.8-1.3-1.11.50.2-1.10.1-1.0
Pavlov. Cond. latency score1.11.43.21.81.0-1.3-1.21.80.1-1.10.1-1.0
Pavlov. Cond. lever contacts0.40.60.91.00.4-0.9-0.91.00.3-0.8-0.0-0.8
Pavlov. Cond. magazine entry number0.50.61.0-0.9-0.21.01.0-0.8-0.51.00.30.9
Pavlov. Cond. intertrial magazine entries0.60.81.6-0.9-0.11.31.2-0.5-0.61.10.51.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.31.50.7-1.3-1.21.40.3-1.1-0.0-1.0
Pavlov. Cond. response bias0.60.81.50.90.2-1.2-1.20.90.6-1.1-0.2-1.1
Conditioned reinforcement - actives0.70.71.5-0.30.41.21.1-0.0-0.81.10.81.1
Conditioned reinforcement - inactives1.51.72.8-0.30.81.31.6-0.1-1.71.61.31.7
Conditioned locomotion0.91.01.90.61.20.60.61.4-1.20.71.40.9
Intermittent access intake day 1-15 change1.81.83.91.62.00.50.81.5-1.70.91.31.1
Intermittent access intake escalation2.02.04.52.02.10.40.71.8-1.60.71.40.9
Intermittent access intake escalation 21.71.75.52.41.9-0.3-0.12.0-0.8-0.11.0-0.0
Intermitt. access day 1 inactive lever presses0.91.05.51.20.9-0.5-0.32.3-0.5-0.4-0.1-0.1
Intermitt. access day 15 inactive lever presses0.30.31.60.2-0.4-0.3-0.4-0.00.5-0.5-1.2-0.5
Intermitt. access escalation Index1.41.34.5-1.8-1.30.80.7-2.10.40.6-0.30.5
Intermittent access day 1 total infusions1.92.23.3-0.70.61.61.8-0.9-1.61.81.81.8
Intermittent access day 15 total infusions5.05.69.60.92.42.12.50.8-3.12.63.02.8
Intermittent access terminal intake (last 3 days)3.74.06.4-0.11.42.22.4-0.6-2.42.42.32.5
Intermittent access total infusions2.52.84.40.21.41.71.90.5-2.11.92.12.0
Intermittent access day 1 locomotion1.92.03.2-0.30.91.71.61.1-1.81.61.21.8
Intermittent access day 15 total locomotion1.81.93.71.01.71.01.31.2-1.91.31.31.5
Intermittent access total locomotion1.11.22.90.10.81.21.01.7-1.41.00.81.2
Intermittent access standard deviation5.25.59.92.13.11.41.92.2-3.12.02.62.2
Cocaine induced anxiety2.12.43.60.9-0.5-1.5-1.81.81.4-1.9-1.9-1.6
Post-drug Anxiety0.70.81.60.1-0.7-0.9-1.0-0.01.1-1.1-1.3-1.0
Baseline Anxiety1.21.23.7-0.50.40.91.1-1.9-0.91.21.31.0
Lifetime Intake3.74.16.50.11.62.12.30.4-2.62.32.52.5
Incentive Sensitization - Responses0.10.10.3-0.5-0.10.50.30.5-0.30.30.40.2
Incentive Sensitization - Breakpoint0.10.10.2-0.4-0.10.50.30.4-0.30.30.30.2
Progressive ratio test 1 active lever presses1.21.31.9-1.00.11.31.4-1.0-1.11.40.81.4
Progressive ratio test 1 breakpoint1.81.92.7-1.4-0.21.51.6-1.6-1.11.60.81.6
Progressive ratio test 1 inactive lever presses1.61.72.80.11.11.31.21.5-1.71.21.51.4
Progressive ratio test 2 active lever presses0.70.81.2-0.60.31.11.0-0.2-1.01.01.11.0
Progressive ratio test 2 breakpoint0.40.40.8-0.50.10.90.70.1-0.70.70.80.7
Progressive ratio test 2 inactive lever presses1.82.13.3-0.11.11.71.70.5-1.81.71.71.7
Total sessions with >9 infusions2.42.64.4-0.60.91.81.9-0.2-2.02.01.72.1
Short access day 1 total inactive lever presses0.20.20.8-0.40.00.30.40.9-0.70.4-0.10.6
Short access day 10 total inactive lever presses0.30.31.1-0.3-0.5-0.3-0.61.00.4-0.6-0.7-0.6
Short access day 1 total infusions3.84.17.70.82.21.52.00.9-2.82.12.52.3
Short access day 10 total infusions1.51.62.7-0.20.81.41.5-0.2-1.61.51.51.6
Short access total infusions4.14.57.80.52.02.02.40.4-2.82.42.52.6
Short access day 1 locomotion1.31.42.70.81.50.71.01.0-1.61.11.31.2
Short access day 10 total locomotion1.21.35.10.41.00.90.72.3-1.50.70.91.0
Short access total locomotion1.11.13.10.41.10.80.81.8-1.50.80.81.1
Compulsive drug intake1.41.42.5-1.0-1.6-0.8-1.10.31.5-1.2-1.5-1.1
One hour access (0.3 mA shock)1.51.73.3-0.20.91.51.50.1-1.51.51.81.6
One hour access (shock baseline)2.42.85.00.31.51.81.8-0.0-2.01.92.21.9
Number of responses in last shaping day1.51.54.21.21.60.30.42.1-1.50.41.40.7
Context. condit. distance diff. score0.81.01.8-1.2-0.41.41.2-1.1-0.41.10.41.1
Locomotion velocity, session 11.92.15.2-2.1-1.11.61.4-2.3-0.11.40.21.2
Locomotion distance, session 10.81.01.6-0.50.31.11.3-1.0-0.91.31.01.3
Locomotion velocity, session 20.50.51.2-0.8-1.1-0.3-0.5-0.71.0-0.5-0.8-0.6
Locomotion distance, session 20.30.41.2-1.0-0.60.50.5-1.10.10.4-0.10.3
Locomotion velocity, session 31.61.83.01.10.0-1.7-1.71.31.0-1.7-1.0-1.6
Locomotion distance, session 30.10.20.20.1-0.2-0.4-0.50.40.4-0.5-0.5-0.4
Stereotopy head waving bouts, day 30.00.00.2-0.2-0.3-0.0-0.10.20.3-0.2-0.4-0.1
Stereotopy head waving duration, day 30.70.92.11.31.4-0.00.31.4-1.00.30.80.5
Locomotion velocity, session 70.10.10.10.10.20.20.20.1-0.30.20.40.3
Locomotion distance, session 70.00.00.1-0.1-0.2-0.0-0.10.00.2-0.1-0.2-0.1
Stereotopy head waving bouts, day 70.70.81.6-0.70.01.31.2-0.4-0.71.20.41.1
Stereotopy head waving duration, day 70.81.02.0-0.9-0.11.41.3-0.6-0.81.30.51.3
Locomotion velocity, session 80.70.91.6-0.60.21.31.2-0.6-0.81.20.81.1
Locomotion distance, session 81.21.83.9-1.9-1.01.71.4-2.0-0.11.30.31.2
Degree of sensitization distance0.50.50.8-0.50.10.90.9-0.6-0.60.90.70.9
Degree of sensitization stereotypy0.91.02.0-1.4-0.71.31.1-1.1-0.31.10.11.0
Condit. Reinf. active minus inactive responses1.11.22.1-0.6-1.2-0.9-1.1-0.61.4-1.1-1.3-1.2
Condit. Reinf. active-inactive response ratio0.70.71.2-0.4-0.9-0.8-0.9-0.31.1-0.9-1.1-0.9
Condit. Reinf. active responses0.81.01.8-0.6-1.2-0.8-0.9-0.71.3-1.0-1.2-1.0
Condit. Reinf. inactive responses0.00.00.10.1-0.1-0.2-0.2-0.10.2-0.2-0.0-0.2
Incentive salience index mean1.62.03.5-1.0-1.7-1.0-1.2-1.11.9-1.3-1.7-1.4
Condit. Reinf. lever presses2.43.26.2-1.8-2.5-0.8-1.2-1.92.4-1.3-2.1-1.5
Time in familiar zone, hab. session 10.20.20.50.60.70.10.20.5-0.50.30.50.3
Time in novel zone, hab. session 10.40.40.7-0.5-0.8-0.3-0.5-0.30.8-0.6-0.8-0.6
Total zone transitions, hab. session 14.05.78.7-0.01.82.62.9-0.4-2.82.92.83.0
Total locomotion distance, hab. session 10.30.40.6-0.30.20.70.8-0.4-0.60.80.70.7
Locomotion velocity, hab. session 10.30.50.8-0.10.50.80.9-0.3-0.80.90.90.9
Time in familiar zone, hab. session 20.30.30.5-0.5-0.7-0.2-0.3-0.60.7-0.3-0.6-0.4
Time in novel zone, hab. session 20.30.30.90.80.4-0.6-0.60.90.1-0.5-0.2-0.5
Total zone transitions, hab. session 22.12.74.3-0.70.61.92.1-1.3-1.62.11.82.0
Total locomotion distance, hab. session 20.40.60.8-0.40.20.80.9-0.8-0.60.90.90.9
Locomotion velocity, hab. session 20.50.61.0-0.30.40.81.0-0.8-0.71.01.01.0
Novel to familiar place preference ratio0.20.20.40.50.60.00.10.6-0.50.20.30.2
Novelty place preference0.00.00.10.20.20.00.00.4-0.10.00.00.0
Time in novel zone, NPP test0.00.00.0-0.0-0.10.1-0.00.20.0-0.0-0.1-0.0
Total zone transitions, NPP test2.63.85.9-0.41.22.12.4-0.8-2.12.42.22.4
Total locomotion distance, NPP test0.30.51.00.50.90.30.60.2-0.90.61.00.7
Locomotion velocity, NPP test0.40.61.51.01.2-0.00.30.5-0.90.41.00.5
Pavlov. Cond. lever latency2.12.64.40.51.61.61.70.7-2.11.81.91.8
Pavlov. Cond. magazine entry latency3.34.37.6-1.0-2.3-1.8-2.1-1.22.8-2.2-2.4-2.3
Pavlov. Cond. change in total contacts1.81.93.20.4-0.7-1.8-1.7-0.01.5-1.8-1.3-1.7
Pavlov. Cond. index score2.43.15.6-1.0-2.0-1.4-1.6-1.32.4-1.7-2.1-1.8
Pavlov. Cond. latency score2.83.56.4-1.2-2.3-1.4-1.7-1.42.5-1.8-2.3-1.9
Pavlov. Cond. lever contacts1.61.93.5-0.6-1.5-1.3-1.4-0.91.9-1.4-1.6-1.5
Pavlov. Cond. magazine entry number1.72.13.70.51.41.41.50.8-1.91.61.61.7
Pavlov. Cond. intertrial magazine entries2.63.25.30.41.71.82.00.4-2.32.11.92.2
Pavlov. Cond. lever-magazine prob. diff.2.22.85.1-0.9-1.9-1.4-1.6-1.22.3-1.7-2.0-1.8
Pavlov. Cond. response bias2.12.54.6-0.7-1.7-1.5-1.6-1.12.1-1.7-1.8-1.7
Bone: apparent density0.71.13.3-1.8-1.50.70.4-1.50.70.3-0.80.2
Bone surface0.61.12.4-1.1-0.31.51.4-0.8-0.61.30.31.3
Bone volume0.91.53.2-1.2-0.21.81.6-0.8-0.91.60.71.5
Bone: connectivity density0.71.23.2-1.8-1.21.20.9-1.60.20.8-0.20.7
Bone: cortical apparent density0.71.02.00.90.1-1.4-1.30.60.7-1.3-0.5-1.2
Bone: cortical area0.20.31.01.00.9-0.4-0.20.9-0.5-0.20.3-0.0
Bone: cortical porosity1.92.14.5-0.8-1.7-1.0-1.3-0.61.8-1.4-2.1-1.5
Bone: cortical porosity1.71.94.2-0.5-1.4-1.1-1.4-0.21.7-1.4-2.0-1.5
Bone: cortical thickness1.62.64.51.1-0.2-2.1-2.11.11.3-2.1-1.5-2.0
Bone: cortical thickness3.44.06.3-0.2-1.6-2.2-2.4-0.12.4-2.4-2.3-2.5
Bone: cortical tissue density0.60.81.70.80.1-1.3-1.20.40.7-1.2-0.4-1.1
Bone: elastic displacement0.20.20.60.80.7-0.6-0.40.4-0.2-0.40.3-0.3
Bone: elastic work0.81.02.21.00.4-1.5-1.30.80.5-1.2-0.4-1.1
Bone: endosteal estimation2.75.99.50.62.32.32.80.4-3.12.82.83.0
Bone: endosteal perimeter2.85.89.00.42.12.42.80.2-3.02.92.73.0
Bone: final force0.50.71.2-0.20.51.01.1-0.2-1.01.10.81.1
Bone: final moment0.50.81.3-0.00.71.01.1-0.0-1.11.11.01.2
Bone: marrow area2.75.89.30.62.32.32.80.4-3.12.82.82.9
Bone: maximum diameter0.81.42.70.91.60.71.10.7-1.61.21.31.3
Bone: maximum force0.50.91.4-0.00.81.01.10.0-1.21.21.11.2
Bone: maximum moment0.71.21.90.21.01.01.20.2-1.41.21.31.3
Bone: minimum diameter1.73.24.90.21.51.92.10.1-2.22.12.02.2
Bone: periosteal estimation1.32.84.90.81.81.41.80.6-2.21.81.91.9
Bone: periosteal perimeter0.91.42.60.61.31.01.20.5-1.61.31.41.4
Bone: post-yield work0.40.51.2-1.1-0.60.90.7-0.9-0.00.7-0.00.6
Bone: stiffness1.32.14.1-1.7-0.62.01.8-1.4-0.71.70.71.6
Bone: tissue strength0.20.20.50.60.7-0.10.10.5-0.50.20.50.2
Bone: trabecular number0.61.02.4-1.5-1.60.1-0.2-1.31.1-0.2-1.0-0.4
Bone: trabecular spacing0.40.51.21.01.10.10.21.0-0.80.30.80.3
Bone: trabecular thickness0.10.20.6-0.7-0.50.50.3-0.50.10.3-0.10.3
Bone: trabecular tissue density1.11.63.51.50.5-1.9-1.61.00.6-1.5-0.6-1.4
Breakpoint value in progressive ratio session1.21.36.7-1.6-0.90.50.8-2.6-0.00.80.30.6
Distance traveled before self-admin0.80.91.91.01.40.10.50.8-1.30.61.20.7
Distance traveled after self-admin5.56.19.30.12.02.62.90.1-3.03.02.83.1
Delta time in closed arm before/after self-admin1.01.01.60.40.90.71.2-0.8-1.31.20.81.2
Delta time in open arm before/after self-admin0.60.61.0-0.70.11.00.9-0.1-0.81.00.71.0
Diff in mean of infusions in LGA sessions0.91.02.3-1.4-1.4-0.1-0.2-1.51.0-0.3-1.2-0.4
Extinction: sum of active levers before priming1.51.55.6-1.7-0.91.01.1-2.4-0.11.0-0.20.9
Active lever presses in extinction session 61.41.33.3-1.2-0.21.01.3-1.8-0.81.30.91.2
Delta distance traveled before/after self-admin2.62.85.6-1.20.22.42.2-0.7-1.42.21.32.1
Delta ambulatory time before/after self-admin1.61.74.0-1.00.12.01.7-0.2-1.11.70.91.7
Time in closed arm before self-admin1.31.43.4-1.6-1.8-0.2-0.7-0.91.5-0.7-1.5-0.9
Time in closed arm after self-admin0.10.10.7-0.0-0.3-0.2-0.20.00.4-0.3-0.8-0.2
Time in open arm before self-admin1.01.13.81.91.2-1.3-0.81.1-0.2-0.70.2-0.6
Time in open arm after self-admin1.41.63.61.21.70.30.61.4-1.60.71.90.9
Sum of active levers in priming session hrs 5-61.61.65.4-2.0-1.70.30.2-2.30.80.2-1.00.1
Time to tail flick, vehicle, before self-admin1.11.24.1-1.6-1.40.30.2-2.00.70.1-1.00.0
Time to tail flick, vehicle, after self-admin0.10.10.20.20.30.40.40.1-0.30.4-0.00.3
Time to tail flick, test, before self-admin3.93.96.2-0.7-2.0-1.7-2.20.12.4-2.2-2.5-2.4
Time to tail flick, test, after self-admin0.80.81.4-0.5-1.0-0.8-1.0-0.21.2-1.0-1.0-1.1
Delta time to tail flick, vehicle, before/after SA1.71.64.01.61.80.40.62.0-1.30.61.30.7
Delta time to tail flick, test, before/after SA1.81.63.20.41.31.01.3-0.0-1.61.41.81.5
Ambulatory time before self-admin0.30.40.90.70.9-0.20.20.2-0.80.20.90.3
Ambulatory time after self-admin2.32.54.2-0.60.62.02.1-0.6-1.72.11.32.1
Total heroin consumption2.53.09.8-3.1-2.50.60.2-2.81.30.1-1.0-0.1
Area under the delay curve0.10.10.30.60.6-0.10.10.2-0.40.10.50.2
Delay disc. indifference point, 0s delay1.71.83.20.10.91.51.8-0.4-1.51.81.11.8
Delay disc. indifference point, 16s delay0.70.71.10.81.10.40.70.5-1.00.71.00.8
Delay disc. indifference point, 2s delay0.10.10.30.60.2-0.5-0.40.40.2-0.4-0.1-0.4
Delay disc. indifference point, 24s delay0.60.61.10.2-0.4-1.0-1.0-0.30.8-1.0-0.6-1.0
Delay disc. indifference point, 4s delay0.40.40.7-0.00.50.70.8-0.1-0.80.80.70.8
Delay disc. indifference point, 8s delay0.00.00.10.00.20.00.1-0.0-0.10.10.30.1
Delay discount exponential model param0.00.00.1-0.4-0.30.30.1-0.00.00.2-0.20.1
Delay discount hyperbolic model param0.00.00.1-0.4-0.30.20.0-0.10.10.1-0.3-0.0
Fecal boli incidents, locomotor time 10.40.40.9-0.2-0.4-0.6-0.70.30.6-0.7-0.9-0.7
Change in fecal boli incidents, locomotor task0.50.40.80.3-0.4-0.8-0.9-0.00.7-0.9-0.6-0.9
Time >=10cm from walls, locomotor time 10.30.30.5-0.2-0.6-0.7-0.7-0.00.7-0.7-0.4-0.7
Bouts of movement, locomotor time 10.70.81.3-0.2-1.0-0.7-0.9-0.31.1-0.9-1.1-1.0
Total resting periods, locomotor time 11.71.93.1-0.0-1.3-1.4-1.5-0.21.6-1.6-1.8-1.7
Rest time, locomotor task time 10.40.50.90.70.1-1.0-0.90.40.5-0.9-0.3-0.8
Distance moved, locomotor task time 10.91.01.7-0.20.61.21.2-0.6-1.11.31.11.3
Vertical activity count, locomotor time 10.90.91.5-0.60.31.21.2-0.4-0.91.20.91.2
Time >=10cm from walls, locomotor time 20.60.71.20.1-0.5-1.0-1.0-0.20.9-1.0-0.7-1.1
Bouts of movement, locomotor time 21.11.21.9-0.0-0.9-1.2-1.30.21.2-1.3-1.1-1.4
Total resting periods, locomotor time 20.80.81.3-0.1-0.9-0.9-1.00.01.1-1.1-1.0-1.1
Rest time, locomotor task time 20.91.01.70.6-0.4-1.1-1.30.31.0-1.3-1.3-1.2
Distance moved, locomotor task time 22.02.34.80.51.41.41.7-0.2-1.71.72.21.7
Vertical activity count, locomotor time 20.70.81.8-0.30.60.91.0-0.2-0.91.01.31.0
Weight adjusted by age2.42.74.2-0.70.71.92.0-0.7-1.82.01.82.0
Seeking ratio, delayed vs. immediate footshock0.40.50.90.90.3-1.0-0.80.80.3-0.7-0.6-0.7
Locomotion in novel chamber2.53.19.62.52.40.20.33.1-1.50.41.70.6
Locomotion in novel chamber post-restriction0.20.30.40.50.0-0.7-0.60.40.2-0.7-0.6-0.5
Progressive ratio0.70.81.70.30.90.60.9-0.4-1.21.01.31.0
Food seeking constrained by brief footshock0.10.10.40.70.2-0.5-0.2-0.40.2-0.30.0-0.4
Seeking ratio, punishment vs. effort1.01.22.00.1-0.9-1.0-1.20.51.4-1.3-1.4-1.3
Run reversals in cocaine runway, females0.20.20.50.50.1-0.3-0.40.70.1-0.4-0.2-0.4
Run reversals in cocaine runway, males2.42.33.51.31.91.01.31.5-1.91.31.71.5
Latency to leave start box in cocaine runway0.20.21.10.0-0.2-0.4-0.1-1.00.4-0.2-0.2-0.2
Latency to leave start box in cocaine runway, F0.60.74.1-0.6-0.7-0.3-0.1-2.00.6-0.1-0.7-0.3
Latency to leave start box in cocaine runway, M0.20.20.50.00.30.50.5-0.1-0.50.50.70.5
Cd content in liver0.91.01.6-0.60.21.21.3-0.9-0.91.31.01.2
Co content in liver0.20.20.3-0.30.10.60.6-0.3-0.30.50.30.5
Cu content in liver2.42.94.4-0.0-1.3-1.9-2.00.22.0-2.1-2.1-2.1
Fe content in liver0.40.51.3-1.1-1.10.2-0.1-0.90.8-0.1-0.7-0.2
K content in liver0.40.41.1-1.0-1.00.20.0-0.90.6-0.0-0.4-0.1
Mg content in liver0.00.00.10.20.2-0.10.00.3-0.20.00.20.1
Mn content in liver1.31.52.6-0.4-1.3-1.2-1.4-0.51.6-1.4-1.3-1.5
Na content in liver0.20.20.40.60.7-0.10.10.5-0.50.20.60.2
Rb content in liver0.70.81.20.00.61.01.1-0.2-1.01.11.11.1
Se content in liver0.80.91.80.6-0.1-1.3-1.30.80.8-1.2-0.6-1.2
Sr content in liver1.31.22.2-0.50.41.51.4-0.6-1.11.40.81.4
Zn content in liver0.10.20.30.40.1-0.5-0.50.30.3-0.5-0.4-0.4