Hub : Genes

Fam89b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000024239 0.06 0.04 1.4e-05 0.02 0.03 0.02 0.02 1.0e-03 2.9e-04 1.2e-03 2.5e-03
2 BLA gene expression ENSRNOG00000024239 0.32 0.12 0.0e+00 0.36 0.34 0.36 0.37 2.0e-20 3.4e-19 6.2e-20 1.1e-20
3 Brain gene expression ENSRNOG00000024239 0.3 0.09 0.0e+00 0.35 0.35 0.34 0.36 8.1e-34 4.3e-34 9.1e-33 2.4e-35
4 IL gene expression ENSRNOG00000024239 0.35 0.14 4.2e-07 0.2 0.23 0.22 0.24 1.2e-05 3.8e-06 6.3e-06 1.8e-06
5 LHb gene expression ENSRNOG00000024239 0.12 0.07 8.5e-03 0 0.06 0.02 -0.01 2.6e-01 1.4e-02 9.9e-02 7.2e-01
6 Liver alternative TSS ENSRNOT00000016987 0.03 0.02 1.4e-03 0.01 0.02 0.01 0.01 1.7e-02 5.4e-03 2.0e-02 1.2e-02
7 Liver alternative TSS ENSRNOT00000099768 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.01 1.2e-02 7.6e-03 2.4e-02 1.3e-02
8 Liver gene expression ENSRNOG00000024239 0.04 0.02 1.5e-03 0 0 0.01 0 1.6e-01 1.2e-01 3.9e-02 1.3e-01
9 NAcc gene expression ENSRNOG00000024239 0.21 0.1 2.1e-13 0.17 0.17 0.16 0.17 2.3e-12 1.5e-12 2.8e-12 4.9e-13
10 OFC gene expression ENSRNOG00000024239 0.39 0.15 4.9e-08 0.3 0.26 0.26 0.26 5.9e-08 6.2e-07 5.9e-07 6.8e-07
11 PL gene expression ENSRNOG00000024239 0.26 0.1 0.0e+00 0.28 0.3 0.3 0.3 1.2e-21 2.6e-23 7.0e-23 4.3e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail2.27.219.4-3.3-3.1-2.7-3.1-0.7-0.30.0-4.4-2.5-3.1-2.5
BMI without tail0.91.85.6-1.5-1.5-1.2-1.7-0.4-0.2-0.0-2.4-1.2-1.4-1.4
Body weight3.615.420.9-4.3-4.3-4.1-4.3-3.0-2.82.6-4.6-4.0-4.3-4.1
Epididymis fat weight2.96.88.42.22.72.72.62.82.7-2.72.12.92.62.7
Glucose2.43.75.81.51.81.91.82.32.4-2.41.01.91.92.0
Heart weight3.85.56.42.52.42.42.32.32.4-2.32.12.32.32.5
Left kidney weight0.61.92.61.01.41.31.51.41.2-1.21.61.41.41.4
Right kidney weight0.10.31.3-0.10.60.30.60.40.1-0.11.10.60.50.4
Tail length0.92.65.5-1.0-1.3-1.2-1.4-2.3-2.32.3-0.5-1.4-1.1-1.7
Length with tail2.59.211.2-2.8-3.0-3.0-3.0-3.3-3.33.3-2.2-3.1-2.9-3.2
Length without tail3.06.47.8-2.6-2.6-2.7-2.5-2.4-2.42.3-2.3-2.7-2.8-2.6
Liver weight, left0.10.10.20.20.40.30.30.30.3-0.30.50.40.30.2
Liver weight, right0.10.10.20.40.30.40.20.10.3-0.30.40.40.20.2
Parametrial fat weight2.95.78.41.72.42.32.32.92.9-2.91.42.72.12.4
Retroperitoneal fat weight5.919.521.84.04.64.54.54.64.5-4.43.94.74.34.6
Intraocular pressure0.70.92.50.61.20.81.30.60.3-0.21.61.11.11.0
Extensor digitorum longus weight7.730.835.9-5.9-6.0-5.8-6.0-4.8-4.74.4-5.6-5.9-5.9-5.9
Soleus weight4.513.014.83.63.83.83.73.33.2-3.13.63.93.83.7
Tibialis anterior weight11.840.845.5-6.6-6.6-6.6-6.6-6.1-6.26.0-5.4-6.6-6.6-6.7
Tibia length1.43.87.4-2.7-1.8-2.2-1.7-1.6-2.01.9-1.4-1.8-2.1-1.9
Number of licking bursts0.30.40.5-0.7-0.6-0.7-0.6-0.4-0.50.5-0.7-0.7-0.7-0.6
Food consumed during 24 hour testing period0.10.10.5-0.4-0.1-0.3-0.2-0.5-0.60.70.1-0.2-0.2-0.2
Times rat made contact with spout0.40.51.0-0.3-0.8-0.6-0.8-0.6-0.50.5-1.0-0.8-0.7-0.7
Mean time between licks in bursts0.60.81.5-0.2-0.8-0.7-0.9-1.2-1.01.0-0.7-0.8-1.0-0.9
Mean num. licks in bursts0.20.30.70.80.50.60.40.30.4-0.40.30.50.60.5
Std. dev. time between licks in bursts0.10.10.60.80.30.40.2-0.4-0.20.20.60.20.20.1
Water consumed over 24 hours0.91.01.4-0.7-1.0-1.0-1.0-1.2-1.11.1-1.0-1.1-0.9-1.0
Indifference point 0 sec0.00.10.10.20.30.10.30.30.3-0.30.20.20.10.3
Indifference point AUC4.14.85.8-2.4-2.2-2.3-2.3-1.9-2.12.0-2.0-2.2-2.3-2.2
Indifference point function ln k9.313.216.94.13.83.93.73.13.2-3.13.73.83.73.6
Indifference point function log k9.313.216.94.13.83.93.73.13.2-3.13.73.83.73.6
Delay discounting total patch changes 0 sec0.00.00.10.30.20.00.2-0.0-0.00.00.30.10.00.1
Delay discounting total patch changes 12 sec5.26.98.4-2.7-2.8-2.9-2.8-2.2-2.22.1-2.7-2.8-2.9-2.6
Delay discounting total patch changes 18 sec0.60.71.3-1.1-1.0-1.0-0.9-0.4-0.50.4-1.1-0.9-0.9-0.8
Delay discounting total patch changes 24 sec3.03.74.2-1.8-1.9-2.0-1.9-2.0-2.02.0-1.7-2.0-2.0-1.9
Delay discounting total patch changes 6 sec1.11.72.7-1.1-1.5-1.4-1.4-1.0-0.90.8-1.4-1.6-1.6-1.2
Delay discounting time to switch 0 sec1.62.55.6-2.1-1.8-1.7-1.7-0.4-0.40.3-2.4-1.6-1.8-1.4
Delay discounting water rate 0 sec3.86.011.42.82.82.62.71.41.3-1.13.42.62.82.4
Delay discounting water rate 12 sec8.512.719.34.44.03.93.82.12.2-1.94.43.84.03.5
Delay discounting water rate 18 sec3.34.47.02.62.12.32.21.41.6-1.52.42.02.42.1
Delay discounting water rate 24 sec4.35.99.82.82.62.62.61.51.5-1.43.12.62.82.4
Delay discounting water rate 6 sec3.75.49.13.02.52.62.41.31.4-1.23.02.32.62.3
Locomotor activity1.62.65.02.21.81.81.60.80.9-0.72.21.51.71.6
Locomotor testing distance2.33.88.02.82.12.31.90.91.1-0.92.51.92.11.9
Locomotor testing rearing2.13.36.42.51.92.11.81.11.3-1.21.81.82.01.9
Light reinforcement 10.10.20.50.70.60.50.40.10.1-0.10.60.50.50.4
Light reinforcement 20.81.11.60.41.21.01.21.00.8-0.71.31.31.11.1
Reaction time number correct0.40.61.1-0.6-0.7-0.6-0.7-1.0-1.01.1-0.3-0.6-0.5-0.8
Reaction time mean minus median3.34.37.0-2.7-2.1-2.3-2.1-1.5-1.71.6-2.1-2.1-2.3-2.1
Reaction time mean minus median AUC2.02.53.6-1.9-1.6-1.7-1.6-1.4-1.51.5-1.2-1.6-1.7-1.6
Reaction time num false alarms0.20.31.31.10.60.60.50.10.2-0.20.90.40.50.4
Reaction time num false alarms AUC0.10.10.30.5-0.1-0.0-0.2-0.5-0.30.30.3-0.3-0.3-0.3
Reaction time trials correct on left0.40.61.1-0.6-0.7-0.6-0.7-1.0-1.01.1-0.3-0.6-0.5-0.8
Reaction time trials on left0.50.81.4-0.7-0.8-0.7-0.8-1.2-1.21.2-0.3-0.7-0.6-0.9
Reaction time mean0.00.10.3-0.6-0.2-0.3-0.1-0.0-0.20.2-0.0-0.2-0.2-0.2
Reaction time mean AUC0.00.00.3-0.5-0.1-0.3-0.10.2-0.00.0-0.0-0.1-0.2-0.1
Median of all reaction times0.10.10.2-0.00.20.20.30.40.3-0.30.30.30.30.3
Reaction time omissions1.41.92.5-1.5-1.4-1.4-1.4-1.2-1.31.2-1.2-1.4-1.6-1.5
Reaction time false alarm rate0.20.31.01.00.60.60.50.30.4-0.40.70.30.40.4
Reaction time premature initiation rate2.53.45.2-1.2-1.7-1.7-1.9-2.3-2.02.0-1.5-1.7-1.9-2.0
Reaction time premature initiations4.36.19.3-1.8-2.3-2.3-2.5-3.0-2.82.8-1.8-2.3-2.4-2.7
Std. dev. reaction times0.91.22.3-1.5-1.1-1.3-1.1-0.8-1.00.9-0.9-1.1-1.3-1.1
Reaction time trials completed0.50.81.4-0.7-0.8-0.7-0.8-1.2-1.21.2-0.3-0.7-0.6-0.9
Reaction time trials AUC0.30.40.9-0.5-0.6-0.5-0.6-0.9-0.90.9-0.2-0.5-0.5-0.7
Social response proportion0.91.01.4-1.2-1.0-1.2-0.9-0.8-0.90.8-1.2-1.0-1.1-1.0
Social responses0.30.40.6-0.5-0.6-0.7-0.6-0.8-0.80.8-0.4-0.7-0.6-0.6
Social time0.50.61.0-0.5-0.8-0.7-0.7-1.0-1.01.0-0.5-0.8-0.6-0.8
Conditioned locomotion1.72.12.4-1.4-1.5-1.5-1.5-1.5-1.41.4-1.2-1.5-1.4-1.6
Cocaine response after cond. corrected1.71.92.91.71.41.61.41.11.3-1.21.31.41.51.3
Cocaine response after cond. not corrected1.31.52.11.51.21.41.21.01.1-1.11.11.21.31.2
Cocaine response before conditioning0.70.91.4-1.2-0.9-1.1-0.9-0.7-0.80.8-0.8-0.9-1.1-0.9
Saline control response4.45.86.9-2.2-2.5-2.5-2.5-2.3-2.12.1-2.5-2.5-2.6-2.5
Condit. Reinf. active minus inactive responses0.10.20.4-0.00.20.10.40.70.5-0.6-0.10.30.40.4
Condit. Reinf. active-inactive response ratio0.70.71.70.10.70.60.91.31.1-1.10.40.70.90.9
Condit. Reinf. active responses0.10.10.8-0.3-0.3-0.3-0.20.30.2-0.3-0.9-0.3-0.2-0.0
Condit. Reinf. inactive responses0.30.41.4-0.2-0.7-0.5-0.7-0.4-0.20.2-1.2-0.6-0.6-0.5
Condit. Reinf. lever presses2.53.45.2-2.3-2.0-2.1-1.9-1.3-1.41.3-2.0-2.1-1.9-1.8
Condit. Reinf. lever reinforcers received0.30.41.4-0.7-0.7-0.7-0.6-0.1-0.20.2-1.2-0.7-0.5-0.4
Pavlov. Cond. lever latency0.50.71.61.31.01.00.90.50.6-0.60.90.90.80.8
Pavlov. Cond. magazine entry latency3.94.55.9-2.2-2.4-2.2-2.3-1.5-1.51.4-2.4-2.4-2.3-2.1
Pavlov. Cond. change in total contacts2.12.95.5-2.3-1.9-1.9-1.7-0.9-1.11.0-2.0-1.8-1.8-1.6
Pavlov. Cond. index score2.63.45.4-2.3-2.1-2.0-1.9-1.2-1.31.2-2.1-2.1-1.9-1.8
Pavlov. Cond. latency score2.12.74.5-2.1-1.9-1.8-1.7-1.0-1.11.0-1.8-1.9-1.7-1.6
Pavlov. Cond. lever contacts0.60.91.5-1.2-0.9-1.0-0.9-0.8-0.90.9-0.7-1.0-0.9-0.9
Pavlov. Cond. magazine entry number7.08.610.73.23.33.13.12.22.3-2.23.33.23.12.9
Pavlov. Cond. intertrial magazine entries1.31.72.21.21.41.41.41.11.1-1.11.41.41.51.3
Pavlov. Cond. lever-magazine prob. diff.3.24.16.1-2.5-2.3-2.2-2.1-1.4-1.51.4-2.3-2.3-2.1-2.0
Pavlov. Cond. response bias2.12.84.2-2.0-1.8-1.8-1.7-1.3-1.41.4-1.7-1.8-1.7-1.7
Conditioned reinforcement - actives0.10.10.3-0.00.40.30.40.30.1-0.10.50.30.60.4
Conditioned reinforcement - inactives5.86.68.12.32.82.52.82.52.2-2.12.82.62.72.8
Conditioned locomotion7.99.513.03.13.43.23.42.62.4-2.23.63.13.33.3
Intermittent access intake day 1-15 change0.50.51.50.50.80.50.90.40.1-0.11.20.60.80.7
Intermittent access intake escalation0.50.51.00.50.80.50.80.60.3-0.31.00.60.80.8
Intermittent access intake escalation 20.20.20.70.10.50.20.5-0.0-0.30.30.80.40.40.3
Intermitt. access day 1 inactive lever presses2.52.73.21.61.71.61.81.71.6-1.51.61.71.61.8
Intermitt. access day 15 inactive lever presses2.22.53.31.31.51.41.71.71.5-1.41.71.31.71.8
Intermitt. access escalation Index4.23.84.82.11.72.11.72.02.2-2.21.31.91.92.0
Intermittent access day 1 total infusions6.87.712.32.22.42.62.53.43.5-3.51.52.42.73.0
Intermittent access day 15 total infusions8.49.411.52.63.02.93.13.43.2-3.12.72.83.33.4
Intermittent access terminal intake (last 3 days)6.06.59.11.92.42.42.63.02.8-2.82.02.32.72.8
Intermittent access total infusions5.25.89.31.82.12.22.23.02.9-3.01.52.02.52.7
Intermittent access day 1 locomotion5.05.19.22.01.82.21.92.83.0-3.01.11.82.12.4
Intermittent access day 15 total locomotion5.25.57.32.02.22.22.42.72.5-2.52.02.02.52.6
Intermittent access total locomotion7.38.213.22.22.52.62.73.63.5-3.61.82.52.83.1
Intermittent access standard deviation1.11.21.81.01.11.11.20.90.8-0.71.31.01.41.2
Cocaine induced anxiety0.00.00.1-0.30.10.00.0-0.0-0.10.20.10.20.0-0.1
Post-drug Anxiety1.61.72.8-1.7-1.1-1.4-1.1-1.4-1.51.5-0.8-1.1-1.3-1.4
Baseline Anxiety3.03.13.8-1.6-1.8-1.9-1.7-1.9-1.81.8-1.3-1.9-1.8-1.9
Lifetime Intake4.75.28.41.81.92.12.12.92.9-2.91.31.82.32.5
Incentive Sensitization - Responses0.40.40.90.30.60.50.60.90.8-0.80.40.40.80.8
Incentive Sensitization - Breakpoint0.70.71.20.50.80.70.81.10.9-0.90.60.61.01.0
Progressive ratio test 1 active lever presses3.13.24.21.71.71.81.81.81.8-1.71.61.62.12.0
Progressive ratio test 1 breakpoint2.72.83.81.61.61.71.71.71.6-1.51.61.52.01.9
Progressive ratio test 1 inactive lever presses1.41.51.91.41.11.31.21.31.3-1.31.01.11.31.4
Progressive ratio test 2 active lever presses4.44.76.21.82.12.12.22.42.2-2.21.91.92.52.5
Progressive ratio test 2 breakpoint5.46.07.92.32.52.42.62.52.3-2.22.42.22.82.7
Progressive ratio test 2 inactive lever presses9.210.613.12.93.23.23.33.63.3-3.32.83.13.43.6
Total sessions with >9 infusions2.12.33.91.41.31.51.31.82.0-2.00.91.31.41.6
Short access day 1 total inactive lever presses4.14.55.42.22.02.02.12.32.3-2.21.92.02.02.3
Short access day 10 total inactive lever presses4.04.46.32.52.12.22.11.81.9-1.82.22.02.12.2
Short access day 1 total infusions3.74.07.01.71.61.91.72.52.6-2.60.91.71.92.1
Short access day 10 total infusions2.32.66.80.90.91.21.02.42.5-2.6-0.10.91.31.6
Short access total infusions1.92.14.61.11.01.31.12.02.1-2.10.41.01.31.5
Short access day 1 locomotion2.93.15.71.71.31.61.52.32.4-2.40.91.11.81.9
Short access day 10 total locomotion2.22.44.71.31.11.41.22.02.1-2.20.51.11.51.7
Short access total locomotion1.91.94.01.20.91.31.11.82.0-2.00.40.91.31.5
Compulsive drug intake2.82.84.6-1.0-1.7-1.4-1.7-2.2-2.02.0-1.3-1.6-1.5-1.8
One hour access (0.3 mA shock)10.812.515.73.33.53.63.63.53.4-3.33.43.34.03.9
One hour access (shock baseline)9.210.613.12.63.33.13.43.53.2-3.13.13.13.53.6
Number of responses in last shaping day1.31.32.11.51.11.21.20.80.8-0.71.31.01.41.2
Context. condit. distance diff. score2.32.73.21.81.71.71.71.61.6-1.61.71.71.61.7
Locomotion velocity, session 10.00.10.20.2-0.00.0-0.1-0.4-0.30.30.2-0.10.1-0.2
Locomotion distance, session 10.40.52.1-0.6-0.9-0.6-0.8-0.20.0-0.1-1.4-0.8-0.6-0.6
Locomotion velocity, session 22.73.14.5-1.9-2.0-1.8-2.0-1.3-1.21.1-2.1-1.9-1.8-1.9
Locomotion distance, session 20.60.92.8-0.7-1.2-0.8-1.1-0.5-0.30.2-1.7-1.1-0.8-0.9
Locomotion velocity, session 30.30.31.00.30.20.40.30.81.0-1.00.00.20.40.4
Locomotion distance, session 30.00.00.10.20.10.20.10.20.2-0.20.20.10.10.2
Stereotopy head waving bouts, day 30.91.01.90.90.91.10.81.11.3-1.40.31.10.90.9
Stereotopy head waving duration, day 31.01.21.70.91.11.21.01.11.2-1.30.61.31.21.1
Locomotion velocity, session 70.80.92.60.50.40.70.61.51.5-1.6-0.10.50.60.8
Locomotion distance, session 70.10.20.60.50.10.30.10.60.8-0.8-0.10.00.00.3
Stereotopy head waving bouts, day 70.20.30.6-0.00.40.30.50.80.7-0.7-0.00.60.30.5
Stereotopy head waving duration, day 70.81.02.5-1.4-1.1-1.1-1.0-0.4-0.40.3-1.6-0.9-1.1-0.9
Locomotion velocity, session 81.01.31.9-0.7-1.1-1.0-1.2-1.4-1.21.2-0.8-1.2-1.2-1.2
Locomotion distance, session 80.30.41.10.40.40.60.50.91.0-1.00.20.50.50.6
Degree of sensitization distance0.10.10.50.1-0.00.10.00.50.6-0.7-0.40.0-0.10.1
Degree of sensitization stereotypy0.50.51.3-1.1-0.7-0.9-0.7-0.2-0.30.3-0.9-0.6-0.9-0.6
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.5-0.4-0.4-0.2-0.10.1-0.6-0.5-0.3-0.4
Condit. Reinf. active-inactive response ratio0.00.00.10.0-0.2-0.2-0.1-0.1-0.10.1-0.2-0.30.1-0.1
Condit. Reinf. active responses0.10.10.1-0.3-0.3-0.3-0.30.20.2-0.2-0.3-0.4-0.1-0.1
Condit. Reinf. inactive responses0.10.10.5-0.20.10.10.10.70.7-0.7-0.00.10.10.2
Incentive salience index mean0.20.30.7-0.6-0.7-0.5-0.6-0.1-0.0-0.0-0.9-0.7-0.5-0.5
Condit. Reinf. lever presses0.30.40.9-0.9-0.7-0.6-0.7-0.2-0.20.2-0.6-0.6-0.6-0.7
Time in familiar zone, hab. session 10.30.30.60.40.50.50.50.70.8-0.80.30.50.50.5
Time in novel zone, hab. session 10.20.20.60.80.50.50.4-0.2-0.10.20.60.40.50.3
Total zone transitions, hab. session 10.71.01.5-1.0-1.2-1.1-1.1-0.7-0.70.6-1.2-1.2-1.1-1.0
Total locomotion distance, hab. session 10.40.51.10.50.60.70.61.01.0-1.00.40.70.60.7
Locomotion velocity, hab. session 10.10.10.30.00.10.20.10.50.5-0.6-0.10.20.10.2
Time in familiar zone, hab. session 20.10.10.30.50.10.20.1-0.4-0.30.30.40.00.1-0.0
Time in novel zone, hab. session 20.10.10.4-0.4-0.3-0.3-0.20.20.2-0.2-0.6-0.2-0.2-0.1
Total zone transitions, hab. session 21.31.66.5-1.3-1.5-1.2-1.4-0.3-0.1-0.0-2.6-1.2-1.2-1.1
Total locomotion distance, hab. session 20.30.31.20.10.00.30.00.81.0-1.1-0.80.30.20.2
Locomotion velocity, hab. session 20.40.51.70.10.20.50.31.11.2-1.3-0.60.50.40.4
Novel to familiar place preference ratio1.11.12.6-1.6-1.1-1.2-1.0-0.6-0.80.7-1.2-1.0-1.1-1.0
Novelty place preference0.40.51.3-1.1-0.7-0.8-0.6-0.2-0.40.4-0.8-0.6-0.7-0.6
Time in novel zone, NPP test0.30.30.9-0.9-0.6-0.7-0.5-0.2-0.30.3-0.7-0.5-0.6-0.5
Total zone transitions, NPP test2.13.15.5-1.9-2.0-1.8-1.9-1.2-1.11.0-2.3-1.8-1.8-1.8
Total locomotion distance, NPP test0.10.10.4-0.2-0.2-0.1-0.20.30.4-0.4-0.6-0.1-0.1-0.2
Locomotion velocity, NPP test0.10.10.4-0.3-0.3-0.2-0.30.20.3-0.3-0.7-0.2-0.2-0.2
Pavlov. Cond. lever latency0.20.30.60.70.50.50.60.20.2-0.10.70.40.70.6
Pavlov. Cond. magazine entry latency0.20.20.9-0.6-0.4-0.3-0.40.30.3-0.3-1.0-0.2-0.3-0.3
Pavlov. Cond. change in total contacts0.10.10.4-0.6-0.1-0.3-0.20.30.2-0.2-0.4-0.1-0.2-0.1
Pavlov. Cond. index score0.10.10.4-0.6-0.3-0.4-0.4-0.2-0.20.2-0.4-0.2-0.4-0.4
Pavlov. Cond. latency score0.00.00.2-0.4-0.2-0.1-0.20.00.0-0.1-0.4-0.0-0.2-0.2
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.0-0.10.10.1-0.1-0.10.0-0.2-0.1
Pavlov. Cond. magazine entry number0.20.30.70.80.50.60.50.40.6-0.60.40.50.50.6
Pavlov. Cond. intertrial magazine entries0.30.41.00.60.60.50.70.50.3-0.31.00.40.50.7
Pavlov. Cond. lever-magazine prob. diff.0.30.30.7-0.9-0.6-0.6-0.6-0.3-0.40.3-0.7-0.4-0.6-0.6
Pavlov. Cond. response bias0.10.10.3-0.5-0.3-0.4-0.3-0.2-0.30.3-0.2-0.2-0.4-0.3
Bone: apparent density0.40.73.0-0.9-0.9-0.7-0.70.30.4-0.5-1.7-0.7-0.8-0.4
Bone surface4.07.112.5-3.4-3.0-3.0-2.7-1.6-1.61.4-3.5-2.7-2.9-2.6
Bone volume1.42.45.6-2.2-1.7-1.7-1.5-0.4-0.50.3-2.4-1.5-1.6-1.3
Bone: connectivity density2.03.28.1-2.1-2.1-1.9-1.9-0.8-0.70.6-2.8-1.9-1.9-1.6
Bone: cortical apparent density0.30.30.5-0.3-0.6-0.6-0.6-0.7-0.70.7-0.4-0.7-0.5-0.6
Bone: cortical area0.81.22.0-1.4-1.2-1.2-1.1-0.9-1.01.0-0.8-1.2-1.2-1.1
Bone: cortical porosity0.10.10.6-0.3-0.3-0.2-0.20.10.2-0.2-0.8-0.1-0.3-0.2
Bone: cortical porosity0.50.51.6-0.8-0.8-0.7-0.7-0.4-0.40.3-1.3-0.6-0.8-0.7
Bone: cortical thickness3.35.57.0-1.9-2.4-2.3-2.4-2.6-2.62.6-1.4-2.6-2.3-2.4
Bone: cortical thickness0.81.01.9-0.3-0.9-0.8-1.0-1.4-1.31.3-0.2-1.1-0.9-1.0
Bone: cortical tissue density0.40.50.7-0.4-0.7-0.7-0.7-0.8-0.80.8-0.5-0.7-0.6-0.7
Bone: elastic displacement0.91.02.61.61.11.11.10.10.2-0.11.60.90.90.9
Bone: elastic work0.91.22.1-0.4-1.0-0.9-1.0-1.5-1.31.3-0.5-1.2-1.2-1.1
Bone: endosteal estimation1.12.44.90.71.31.41.42.12.2-2.20.51.61.21.5
Bone: endosteal perimeter1.42.85.50.61.41.41.62.32.3-2.30.51.71.51.7
Bone: final force3.04.96.6-2.6-2.4-2.4-2.3-1.8-1.81.7-2.3-2.3-2.4-2.3
Bone: final moment2.64.35.9-2.4-2.2-2.2-2.1-1.7-1.61.6-2.1-2.2-2.3-2.2
Bone: marrow area1.22.65.20.81.41.41.52.22.2-2.30.51.71.21.5
Bone: maximum diameter0.20.41.5-1.2-0.5-0.7-0.4-0.3-0.50.5-0.4-0.4-0.6-0.5
Bone: maximum force3.35.79.3-3.0-2.7-2.6-2.5-1.4-1.31.2-3.0-2.5-2.7-2.4
Bone: maximum moment2.84.97.8-2.8-2.5-2.4-2.3-1.2-1.21.1-2.8-2.3-2.5-2.2
Bone: minimum diameter1.12.15.00.71.01.21.22.12.2-2.20.11.21.11.4
Bone: periosteal estimation0.10.20.5-0.60.00.00.20.70.6-0.7-0.20.2-0.00.2
Bone: periosteal perimeter0.10.20.8-0.9-0.4-0.5-0.30.20.1-0.1-0.7-0.3-0.4-0.3
Bone: post-yield work1.11.54.9-1.7-0.8-0.7-0.61.51.4-1.6-2.2-0.4-0.5-0.2
Bone: stiffness2.64.17.1-2.7-2.3-2.3-2.1-1.0-1.10.9-2.7-2.1-2.2-2.0
Bone: tissue strength0.10.10.2-0.4-0.2-0.3-0.20.1-0.0-0.0-0.4-0.2-0.3-0.1
Bone: trabecular number0.50.83.0-1.2-1.0-0.9-0.80.20.1-0.2-1.7-0.9-0.9-0.6
Bone: trabecular spacing0.30.30.91.00.60.70.50.10.2-0.20.80.60.60.4
Bone: trabecular thickness0.60.71.60.60.60.70.81.21.2-1.30.10.60.60.9
Bone: trabecular tissue density3.55.06.12.22.52.42.41.91.7-1.72.52.42.42.3
Breakpoint value in progressive ratio session3.53.95.1-2.3-2.0-2.2-2.1-1.7-1.81.7-1.9-2.0-2.1-2.0
Distance traveled before self-admin0.60.61.4-1.2-0.8-0.8-0.8-0.5-0.70.6-0.8-0.6-0.8-0.8
Distance traveled after self-admin0.20.30.5-0.7-0.5-0.6-0.4-0.4-0.50.5-0.4-0.5-0.6-0.5
Delta time in closed arm before/after self-admin0.10.10.30.5-0.10.0-0.2-0.4-0.10.1-0.0-0.3-0.1-0.2
Delta time in open arm before/after self-admin0.10.10.4-0.6-0.3-0.4-0.1-0.2-0.40.4-0.0-0.2-0.3-0.2
Diff in mean of infusions in LGA sessions0.50.60.9-0.7-0.8-0.8-0.7-0.9-1.01.0-0.4-0.8-0.7-0.8
Extinction: sum of active levers before priming4.64.76.3-2.4-2.3-2.3-2.3-1.6-1.61.5-2.5-2.2-2.4-2.2
Active lever presses in extinction session 63.13.04.1-2.0-1.6-1.7-1.6-1.8-2.01.9-1.2-1.6-1.5-1.8
Delta distance traveled before/after self-admin0.00.00.20.40.00.00.1-0.1-0.00.10.3-0.10.10.1
Delta ambulatory time before/after self-admin0.00.00.20.4-0.0-0.00.0-0.3-0.20.20.2-0.1-0.0-0.0
Time in closed arm before self-admin0.00.10.3-0.6-0.2-0.2-0.10.10.0-0.1-0.3-0.0-0.2-0.1
Time in closed arm after self-admin0.00.00.10.30.10.20.10.20.4-0.40.10.10.00.1
Time in open arm before self-admin0.70.72.61.60.90.90.60.40.6-0.60.70.60.90.7
Time in open arm after self-admin0.20.20.50.60.50.40.4-0.1-0.10.20.70.40.50.4
Sum of active levers in priming session hrs 5-62.42.44.0-1.9-1.3-1.7-1.2-1.6-2.02.0-0.4-1.4-1.3-1.5
Time to tail flick, vehicle, before self-admin0.40.41.0-0.9-0.6-0.6-0.7-0.2-0.20.1-1.0-0.5-0.6-0.6
Time to tail flick, vehicle, after self-admin1.01.12.4-1.0-1.1-1.0-1.2-0.7-0.50.4-1.6-1.1-1.1-1.1
Time to tail flick, test, before self-admin1.11.12.61.00.61.00.71.41.6-1.60.10.70.91.0
Time to tail flick, test, after self-admin0.00.00.1-0.10.0-0.2-0.1-0.3-0.30.30.1-0.0-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.4-0.7-0.6-0.7-0.5-0.30.2-0.8-0.7-0.7-0.6
Delta time to tail flick, test, before/after SA2.11.94.5-1.2-0.7-1.3-1.0-1.9-2.12.1-0.2-0.9-1.1-1.4
Ambulatory time before self-admin0.40.51.5-1.2-0.7-0.8-0.5-0.3-0.50.5-0.7-0.6-0.7-0.6
Ambulatory time after self-admin0.10.10.4-0.20.10.00.30.60.5-0.5-0.00.30.10.3
Total heroin consumption6.17.38.3-2.8-2.8-2.8-2.9-2.4-2.42.4-2.7-2.8-2.8-2.8
Area under the delay curve0.20.20.60.40.20.40.10.60.7-0.8-0.30.30.30.4
Delay disc. indifference point, 0s delay0.80.91.51.00.71.20.61.01.2-1.20.11.01.00.8
Delay disc. indifference point, 16s delay1.01.01.80.90.90.90.91.31.3-1.30.60.90.91.1
Delay disc. indifference point, 2s delay0.10.10.30.20.30.40.10.50.5-0.60.10.40.40.4
Delay disc. indifference point, 24s delay0.10.10.40.70.30.40.3-0.10.1-0.00.30.30.30.2
Delay disc. indifference point, 4s delay0.30.30.70.80.40.70.30.50.7-0.7-0.00.50.50.5
Delay disc. indifference point, 8s delay0.10.10.30.60.10.40.20.30.4-0.5-0.20.30.30.3
Delay discount exponential model param0.10.10.4-0.4-0.1-0.3-0.1-0.4-0.60.60.3-0.3-0.3-0.3
Delay discount hyperbolic model param0.10.10.3-0.3-0.1-0.3-0.0-0.4-0.50.50.3-0.2-0.2-0.2
Fecal boli incidents, locomotor time 10.10.10.8-0.9-0.1-0.4-0.20.1-0.20.1-0.1-0.0-0.2-0.2
Change in fecal boli incidents, locomotor task0.10.00.20.5-0.10.20.10.00.3-0.3-0.2-0.1-0.1-0.0
Time >=10cm from walls, locomotor time 11.21.23.00.10.80.80.91.71.7-1.70.11.00.81.0
Bouts of movement, locomotor time 11.71.92.3-1.3-1.4-1.5-1.2-1.4-1.51.5-1.2-1.4-1.4-1.3
Total resting periods, locomotor time 11.21.31.6-1.2-1.2-1.3-1.0-1.0-1.21.2-1.1-1.1-1.2-1.1
Rest time, locomotor task time 11.21.32.11.11.31.21.20.80.7-0.71.41.31.31.1
Distance moved, locomotor task time 10.10.10.5-0.3-0.5-0.3-0.30.20.3-0.4-0.7-0.5-0.3-0.2
Vertical activity count, locomotor time 11.41.51.71.31.21.21.31.11.1-1.11.31.11.31.3
Time >=10cm from walls, locomotor time 20.00.00.3-0.5-0.1-0.1-0.00.1-0.0-0.0-0.3-0.0-0.1-0.1
Bouts of movement, locomotor time 20.50.60.8-0.7-0.8-0.9-0.7-0.7-0.70.7-0.8-0.9-0.9-0.7
Total resting periods, locomotor time 20.20.30.5-0.5-0.6-0.6-0.4-0.3-0.40.4-0.7-0.6-0.7-0.4
Rest time, locomotor task time 22.73.23.91.61.82.01.81.71.7-1.71.61.91.91.8
Distance moved, locomotor task time 21.31.51.9-1.1-1.3-1.3-1.3-1.3-1.31.2-1.0-1.4-1.1-1.3
Vertical activity count, locomotor time 20.20.20.60.50.1-0.00.1-0.7-0.70.80.8-0.10.0-0.2
Weight adjusted by age2.73.03.6-1.9-1.8-1.9-1.5-1.6-1.71.6-1.6-1.9-1.7-1.8
Seeking ratio, delayed vs. immediate footshock0.10.10.30.30.10.10.10.50.6-0.6-0.30.1-0.10.3
Locomotion in novel chamber4.75.86.72.02.52.42.62.42.2-2.12.62.42.62.6
Locomotion in novel chamber post-restriction3.23.84.61.82.02.02.01.91.8-1.72.11.92.22.1
Progressive ratio1.92.26.2-1.9-1.7-1.4-1.6-0.5-0.30.2-2.5-1.4-1.6-1.4
Food seeking constrained by brief footshock0.20.20.4-0.1-0.5-0.4-0.5-0.6-0.50.5-0.3-0.7-0.5-0.5
Seeking ratio, punishment vs. effort1.62.04.82.11.61.41.50.40.5-0.32.21.21.51.3
Run reversals in cocaine runway, females0.30.31.2-0.2-0.7-0.3-0.70.10.4-0.5-1.1-0.6-0.7-0.5
Run reversals in cocaine runway, males0.40.31.80.60.60.40.4-0.3-0.40.51.30.40.60.3
Latency to leave start box in cocaine runway0.20.20.6-0.0-0.00.10.10.70.8-0.8-0.3-0.0-0.00.3
Latency to leave start box in cocaine runway, F0.10.10.2-0.1-0.2-0.1-0.00.40.4-0.4-0.4-0.2-0.10.1
Latency to leave start box in cocaine runway, M0.00.00.1-0.1-0.0-0.00.00.20.3-0.3-0.0-0.1-0.20.0
Cd content in liver1.11.32.00.91.31.11.30.90.7-0.61.41.21.41.2
Co content in liver1.41.74.12.01.51.41.30.30.4-0.21.81.31.41.2
Cu content in liver0.30.30.6-0.6-0.7-0.6-0.6-0.3-0.30.3-0.7-0.7-0.8-0.5
Fe content in liver0.20.20.4-0.6-0.3-0.4-0.4-0.4-0.40.4-0.2-0.3-0.7-0.5
K content in liver1.51.53.2-1.4-1.5-1.3-1.4-0.5-0.40.3-1.8-1.4-1.4-1.2
Mg content in liver0.40.41.5-0.3-0.5-0.2-0.40.60.8-0.9-1.2-0.3-0.3-0.0
Mn content in liver3.03.44.8-2.2-1.9-2.0-1.9-1.5-1.61.5-1.9-1.9-2.0-1.8
Na content in liver1.31.42.1-1.4-1.1-1.2-1.1-1.2-1.31.3-0.7-1.1-1.1-1.3
Rb content in liver1.72.23.31.51.31.51.41.71.8-1.80.71.41.21.6
Se content in liver0.10.10.4-0.6-0.2-0.2-0.00.40.3-0.3-0.6-0.2-0.10.1
Sr content in liver3.93.55.0-1.8-1.7-1.9-1.8-2.1-2.22.2-1.1-1.8-1.8-1.9
Zn content in liver1.11.31.9-1.2-1.3-1.2-1.2-0.8-0.80.8-1.4-1.2-1.1-1.1