Hub : Genes

Bivm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000022894 0.14 0.08 0.0e+00 0.1 0.11 0.11 0.11 1.1e-11 1.3e-12 3.5e-12 6.4e-12
2 Adipose intron excision ratio chr9:46284450:46289214 0.1 0.07 4.2e-12 0.07 0.06 0.06 0.06 3.3e-08 2.4e-07 9.6e-08 1.9e-07
3 Adipose intron excision ratio chr9:46285324:46289214 0.04 0.03 3.6e-05 0.02 0.02 0.01 0.01 3.4e-03 4.8e-03 1.4e-02 6.7e-03
4 Adipose mRNA stability ENSRNOG00000022894 0.12 0.08 1.1e-16 0.09 0.09 0.09 0.09 1.3e-10 2.9e-10 2.5e-10 2.3e-10
5 BLA gene expression ENSRNOG00000022894 0.07 0.06 7.1e-04 0.07 0.06 0.07 0.06 9.3e-05 4.6e-04 1.2e-04 2.5e-04
6 Brain gene expression ENSRNOG00000022894 0.06 0.06 4.7e-04 0.03 0.03 0.03 0.03 4.1e-04 6.5e-04 6.5e-04 3.5e-04
7 Brain mRNA stability ENSRNOG00000022894 0.05 0.04 1.8e-04 0.03 0.03 0.03 0.03 4.8e-04 1.1e-03 2.2e-03 1.4e-03
8 Liver gene expression ENSRNOG00000022894 0.25 0.16 0.0e+00 0.16 0.16 0.17 0.16 1.0e-17 1.0e-17 5.0e-18 1.3e-17
9 Liver intron excision ratio chr9:46284450:46289214 0.05 0.04 2.5e-06 0.03 0.03 0.03 0.02 3.2e-04 6.8e-04 5.8e-04 1.4e-03
10 Liver intron excision ratio chr9:46285324:46289214 0.02 0.02 2.5e-03 0.01 0.01 0 0.01 2.4e-02 3.7e-02 3.7e-01 6.6e-02
11 Liver mRNA stability ENSRNOG00000022894 0.06 0.04 1.6e-07 0.04 0.04 0.03 0.03 1.8e-05 9.0e-05 7.6e-04 1.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail3.09.711.32.83.4-3.13.13.42.63.03.43.0-3.13.4
BMI without tail0.00.10.2-0.2-0.20.3-0.3-0.2-0.1-0.4-0.2-0.30.3-0.2
Body weight0.10.50.70.90.6-0.70.70.60.80.70.80.6-0.70.6
Epididymis fat weight0.00.00.1-0.2-0.10.0-0.1-0.1-0.3-0.0-0.1-0.2-0.0-0.1
Glucose0.00.00.1-0.0-0.10.1-0.2-0.10.1-0.2-0.2-0.20.1-0.1
Heart weight0.30.40.80.40.6-0.70.70.60.20.80.60.8-0.90.6
Left kidney weight0.10.20.9-0.7-0.50.3-0.2-0.5-0.9-0.1-0.6-0.20.2-0.5
Right kidney weight0.00.10.7-0.5-0.20.1-0.1-0.2-0.8-0.1-0.4-0.20.2-0.2
Tail length1.44.35.7-1.5-2.42.1-2.1-2.4-1.1-2.2-2.1-2.12.2-2.4
Length with tail0.51.72.3-0.9-1.51.3-1.3-1.5-0.8-1.3-1.3-1.31.2-1.5
Length without tail1.22.63.21.41.6-1.71.71.61.21.71.61.7-1.81.6
Liver weight, left0.40.72.8-1.2-0.60.6-0.6-0.6-1.7-0.5-0.9-0.50.5-0.6
Liver weight, right0.20.40.6-0.7-0.70.4-0.5-0.7-0.8-0.4-0.7-0.50.6-0.7
Parametrial fat weight0.10.20.40.30.6-0.30.30.60.30.30.40.4-0.40.6
Retroperitoneal fat weight0.30.81.10.71.0-0.90.91.00.51.00.91.0-0.91.0
Intraocular pressure2.63.74.32.02.0-1.91.92.02.11.92.01.8-1.82.0
Extensor digitorum longus weight6.224.827.44.65.1-5.15.15.14.05.24.85.2-5.25.1
Soleus weight0.72.12.70.91.6-1.61.51.60.41.61.21.6-1.61.6
Tibialis anterior weight1.96.77.72.22.8-2.72.72.81.82.72.52.7-2.72.8
Tibia length0.10.30.4-0.7-0.50.6-0.6-0.5-0.6-0.6-0.6-0.50.5-0.5
Number of licking bursts0.40.40.5-0.7-0.70.6-0.6-0.7-0.6-0.6-0.7-0.60.6-0.7
Food consumed during 24 hour testing period0.91.01.31.10.9-1.11.10.91.01.01.01.1-1.00.9
Times rat made contact with spout0.40.50.6-0.4-0.80.7-0.7-0.8-0.2-0.8-0.6-0.80.8-0.8
Mean time between licks in bursts0.81.21.60.61.2-1.31.31.2-0.01.30.81.2-1.31.2
Mean num. licks in bursts0.40.40.60.70.7-0.60.60.70.70.60.80.5-0.60.7
Std. dev. time between licks in bursts0.50.61.00.50.8-0.90.90.80.10.90.61.0-0.90.8
Water consumed over 24 hours0.30.40.90.90.5-0.60.60.50.90.60.70.6-0.60.5
Indifference point 0 sec0.20.32.0-0.50.1-0.60.60.1-1.40.6-0.10.4-0.50.1
Indifference point AUC1.31.52.11.11.3-1.31.31.31.01.31.01.5-1.21.3
Indifference point function ln k0.10.10.30.40.3-0.50.40.30.00.40.60.3-0.40.3
Indifference point function log k0.10.10.30.40.3-0.50.40.30.00.40.60.3-0.40.3
Delay discounting total patch changes 0 sec0.30.51.3-0.20.5-0.90.90.5-1.10.90.30.7-0.80.5
Delay discounting total patch changes 12 sec0.10.10.6-0.50.2-0.30.30.2-0.80.2-0.40.2-0.20.2
Delay discounting total patch changes 18 sec1.31.72.60.81.3-1.61.61.30.21.51.01.5-1.51.3
Delay discounting total patch changes 24 sec0.20.30.6-0.10.2-0.70.70.2-0.70.7-0.10.6-0.70.2
Delay discounting total patch changes 6 sec0.10.21.7-0.7-0.0-0.10.2-0.0-1.30.1-0.40.2-0.1-0.0
Delay discounting time to switch 0 sec0.71.01.5-1.1-0.81.1-1.1-0.8-0.7-1.2-1.0-1.21.0-0.8
Delay discounting water rate 0 sec0.71.11.51.10.8-1.21.10.80.71.21.01.1-1.20.8
Delay discounting water rate 12 sec0.10.10.8-0.3-0.0-0.10.2-0.0-0.90.20.00.1-0.2-0.0
Delay discounting water rate 18 sec0.60.81.2-1.0-1.00.8-0.8-1.0-1.1-0.7-1.0-0.80.9-1.0
Delay discounting water rate 24 sec0.00.00.10.10.00.1-0.10.00.2-0.10.3-0.00.00.0
Delay discounting water rate 6 sec0.00.00.3-0.2-0.00.0-0.1-0.0-0.6-0.0-0.10.00.0-0.0
Locomotor activity0.20.30.5-0.5-0.40.6-0.7-0.4-0.5-0.6-0.6-0.60.7-0.4
Locomotor testing distance1.52.53.1-1.7-1.31.7-1.7-1.3-1.5-1.7-1.6-1.51.7-1.3
Locomotor testing rearing2.13.34.3-1.7-1.82.0-2.0-1.8-1.3-2.1-1.8-1.72.0-1.8
Light reinforcement 13.66.68.62.22.6-2.82.82.61.52.82.42.9-2.82.6
Light reinforcement 21.41.82.40.81.5-1.51.51.50.21.51.11.5-1.41.5
Reaction time number correct0.91.31.91.01.0-1.21.21.00.71.31.11.4-1.31.0
Reaction time mean minus median1.62.13.1-1.4-1.31.5-1.5-1.3-1.2-1.7-1.4-1.61.6-1.3
Reaction time mean minus median AUC1.62.13.0-1.4-1.41.6-1.6-1.4-1.1-1.7-1.3-1.41.5-1.4
Reaction time num false alarms1.82.42.91.61.5-1.71.61.51.41.51.51.7-1.51.5
Reaction time num false alarms AUC2.43.34.11.81.8-2.02.01.81.51.91.72.0-1.91.8
Reaction time trials correct on left0.91.31.91.01.0-1.21.21.00.71.31.11.4-1.31.0
Reaction time trials on left0.81.21.81.01.0-1.11.21.00.71.31.01.3-1.21.0
Reaction time mean2.43.24.4-1.5-1.91.9-1.9-1.9-1.0-2.1-1.9-1.91.8-1.9
Reaction time mean AUC1.72.23.2-1.2-1.61.6-1.6-1.6-0.7-1.8-1.5-1.61.5-1.6
Median of all reaction times1.72.33.1-1.1-1.61.6-1.6-1.6-0.6-1.8-1.6-1.71.4-1.6
Reaction time omissions1.01.41.9-1.1-1.21.2-1.2-1.2-0.8-1.4-1.0-1.31.1-1.2
Reaction time false alarm rate0.71.01.10.91.0-1.11.01.00.90.90.91.0-0.91.0
Reaction time premature initiation rate0.10.10.1-0.4-0.40.4-0.4-0.4-0.3-0.4-0.2-0.10.3-0.4
Reaction time premature initiations0.10.10.40.20.2-0.30.30.20.10.30.40.6-0.40.2
Std. dev. reaction times2.94.05.2-1.9-1.92.1-2.1-1.9-1.6-2.3-2.0-2.12.1-1.9
Reaction time trials completed0.81.21.81.01.0-1.11.21.00.71.31.01.3-1.21.0
Reaction time trials AUC0.81.21.81.00.9-1.11.21.00.71.31.01.3-1.21.0
Social response proportion0.10.10.4-0.0-0.7-0.00.1-0.70.10.1-0.4-0.1-0.3-0.7
Social responses0.60.71.1-0.6-1.11.0-0.9-1.1-0.1-0.8-0.9-0.80.7-1.1
Social time4.15.46.4-2.2-2.52.3-2.3-2.5-2.0-2.3-2.3-2.32.2-2.5
Conditioned locomotion0.00.00.30.2-0.20.1-0.1-0.20.5-0.00.0-0.20.1-0.2
Cocaine response after cond. corrected0.91.01.41.20.9-1.01.00.91.10.91.11.0-1.00.9
Cocaine response after cond. not corrected0.80.91.31.10.9-0.90.90.91.10.81.10.9-0.90.9
Cocaine response before conditioning0.00.00.0-0.2-0.00.1-0.1-0.0-0.1-0.2-0.1-0.20.1-0.0
Saline control response0.10.20.30.50.4-0.40.40.40.40.40.40.5-0.40.4
Condit. Reinf. active minus inactive responses0.30.40.7-0.2-0.70.8-0.8-0.70.3-0.7-0.5-0.70.9-0.7
Condit. Reinf. active-inactive response ratio1.11.21.7-0.8-1.11.2-1.2-1.1-0.4-1.2-1.0-1.21.3-1.1
Condit. Reinf. active responses0.10.10.70.50.3-0.20.20.30.90.20.30.2-0.10.3
Condit. Reinf. inactive responses0.70.91.10.71.1-1.01.01.10.71.00.91.0-1.01.1
Condit. Reinf. lever presses0.40.50.6-0.7-0.60.8-0.8-0.6-0.4-0.8-0.7-0.80.7-0.6
Condit. Reinf. lever reinforcers received0.20.31.00.70.5-0.40.40.51.00.40.50.4-0.30.5
Pavlov. Cond. lever latency0.81.11.31.11.1-1.01.01.11.11.01.10.9-0.91.1
Pavlov. Cond. magazine entry latency0.81.01.1-1.0-1.01.0-1.0-1.0-1.0-0.9-0.9-0.90.9-1.0
Pavlov. Cond. change in total contacts0.71.01.6-1.1-1.10.9-0.9-1.1-1.2-0.9-1.0-0.90.9-1.1
Pavlov. Cond. index score0.70.91.4-1.0-1.00.9-0.9-1.0-1.2-0.9-1.0-0.80.8-1.0
Pavlov. Cond. latency score0.50.71.1-0.9-0.80.8-0.8-0.8-1.0-0.7-0.8-0.60.7-0.8
Pavlov. Cond. lever contacts2.02.83.4-1.8-1.71.6-1.6-1.7-1.9-1.6-1.7-1.41.5-1.7
Pavlov. Cond. magazine entry number1.62.02.61.51.5-1.31.31.51.61.31.41.3-1.31.5
Pavlov. Cond. intertrial magazine entries4.35.66.02.42.5-2.32.32.52.42.32.42.3-2.32.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.2-0.9-0.80.8-0.8-0.8-1.1-0.7-0.8-0.60.7-0.8
Pavlov. Cond. response bias2.73.84.9-2.1-2.01.9-1.9-2.0-2.2-1.8-2.0-1.71.8-2.0
Conditioned reinforcement - actives0.10.10.4-0.10.20.6-0.60.20.4-0.4-0.0-0.40.3-0.1
Conditioned reinforcement - inactives0.20.20.4-0.3-0.40.6-0.6-0.40.1-0.6-0.4-0.60.5-0.6
Conditioned locomotion1.31.62.71.01.6-1.11.21.61.11.11.41.1-1.21.2
Intermittent access intake day 1-15 change0.50.50.8-0.6-0.70.9-0.9-0.8-0.4-0.8-0.7-0.60.6-0.7
Intermittent access intake escalation1.11.11.5-0.7-1.11.2-1.2-1.2-0.4-1.1-0.9-1.01.1-1.1
Intermittent access intake escalation 21.51.52.2-0.9-1.21.5-1.5-1.2-0.3-1.4-1.1-1.21.3-1.2
Intermitt. access day 1 inactive lever presses0.00.00.1-0.2-0.20.2-0.1-0.1-0.1-0.3-0.1-0.40.3-0.0
Intermitt. access day 15 inactive lever presses0.40.40.9-0.9-0.20.9-0.9-0.2-0.5-0.7-0.6-0.60.5-0.3
Intermitt. access escalation Index0.10.10.50.4-0.1-0.00.1-0.20.70.1-0.10.2-0.1-0.3
Intermittent access day 1 total infusions0.10.10.50.30.5-0.10.20.60.70.20.20.2-0.30.3
Intermittent access day 15 total infusions0.60.61.0-0.5-0.71.0-1.0-0.70.0-0.9-0.8-0.90.8-0.8
Intermittent access terminal intake (last 3 days)0.10.10.3-0.20.00.6-0.50.00.4-0.4-0.3-0.40.3-0.2
Intermittent access total infusions0.10.10.2-0.2-0.10.5-0.5-0.10.2-0.4-0.3-0.50.3-0.3
Intermittent access day 1 locomotion0.10.10.40.10.6-0.20.20.60.40.20.20.2-0.20.2
Intermittent access day 15 total locomotion0.00.00.10.20.2-0.00.10.20.30.1-0.00.1-0.20.1
Intermittent access total locomotion0.10.10.40.20.6-0.20.20.60.60.20.30.2-0.30.4
Intermittent access standard deviation0.50.61.0-0.6-0.50.9-1.0-0.5-0.3-1.0-0.7-0.90.8-0.8
Cocaine induced anxiety1.21.41.81.21.1-1.31.31.10.81.31.01.3-1.31.1
Post-drug Anxiety2.83.13.71.91.6-1.81.71.61.91.81.81.7-1.81.7
Baseline Anxiety0.10.10.60.40.10.1-0.10.10.80.10.30.1-0.10.1
Lifetime Intake0.00.10.30.10.30.1-0.10.40.5-0.10.0-0.1-0.00.1
Incentive Sensitization - Responses0.80.81.5-0.7-0.41.2-1.2-0.30.0-1.1-0.6-1.21.1-0.7
Incentive Sensitization - Breakpoint0.60.61.2-0.6-0.31.1-1.1-0.30.0-1.0-0.5-1.00.9-0.6
Progressive ratio test 1 active lever presses0.70.81.20.81.1-0.70.71.11.10.70.70.8-0.90.9
Progressive ratio test 1 breakpoint0.80.81.40.71.1-0.70.81.21.00.80.70.9-0.91.0
Progressive ratio test 1 inactive lever presses0.10.10.2-0.5-0.10.3-0.2-0.0-0.3-0.1-0.3-0.20.10.1
Progressive ratio test 2 active lever presses0.20.20.4-0.10.20.6-0.60.20.6-0.6-0.1-0.60.5-0.1
Progressive ratio test 2 breakpoint0.10.10.50.20.30.3-0.30.40.7-0.30.2-0.20.10.1
Progressive ratio test 2 inactive lever presses0.50.61.0-0.8-0.41.0-1.0-0.3-0.4-0.9-0.8-0.90.8-0.5
Total sessions with >9 infusions2.22.43.31.41.8-1.41.41.81.51.51.41.6-1.61.6
Short access day 1 total inactive lever presses0.30.31.0-1.0-0.10.7-0.6-0.1-0.9-0.5-0.6-0.50.4-0.1
Short access day 10 total inactive lever presses0.50.61.1-0.5-1.10.8-0.7-1.0-0.5-0.7-0.6-0.70.7-0.6
Short access day 1 total infusions0.10.10.3-0.00.5-0.10.10.50.00.20.10.2-0.30.5
Short access day 10 total infusions0.20.20.80.40.5-0.10.20.50.90.30.20.2-0.40.2
Short access total infusions0.70.81.40.81.1-0.70.71.21.10.80.80.7-0.91.0
Short access day 1 locomotion0.20.20.50.30.2-0.60.70.2-0.10.60.10.7-0.70.1
Short access day 10 total locomotion0.20.20.3-0.60.00.4-0.4-0.0-0.5-0.5-0.5-0.50.4-0.5
Short access total locomotion0.50.50.80.60.9-0.80.80.90.50.70.50.8-0.80.5
Compulsive drug intake1.61.61.9-1.4-1.11.4-1.4-1.1-1.0-1.3-1.2-1.31.4-1.2
One hour access (0.3 mA shock)0.30.40.7-0.2-0.50.8-0.8-0.40.4-0.8-0.5-0.70.6-0.6
One hour access (shock baseline)0.10.10.50.5-0.30.2-0.2-0.20.7-0.2-0.0-0.10.1-0.3
Number of responses in last shaping day0.50.50.8-0.6-0.80.8-0.7-0.9-0.7-0.7-0.8-0.40.4-0.5
Context. condit. distance diff. score1.11.31.8-0.8-1.31.3-1.2-1.3-0.5-1.2-1.0-1.11.1-1.3
Locomotion velocity, session 10.10.10.80.50.2-0.10.10.20.90.10.30.1-0.20.2
Locomotion distance, session 11.31.72.91.41.4-1.11.11.41.71.11.41.1-1.11.4
Locomotion velocity, session 23.94.65.61.92.4-2.22.12.41.62.22.12.1-2.12.4
Locomotion distance, session 24.05.77.32.12.7-2.32.22.72.12.32.42.3-2.32.7
Locomotion velocity, session 30.10.20.2-0.4-0.40.4-0.4-0.4-0.3-0.5-0.4-0.50.4-0.4
Locomotion distance, session 30.10.10.1-0.3-0.40.3-0.3-0.4-0.3-0.3-0.3-0.30.2-0.4
Stereotopy head waving bouts, day 30.30.40.5-0.5-0.60.5-0.5-0.6-0.4-0.6-0.6-0.60.7-0.6
Stereotopy head waving duration, day 30.10.10.3-0.1-0.40.4-0.3-0.40.2-0.5-0.2-0.50.6-0.4
Locomotion velocity, session 70.20.30.50.20.7-0.50.50.7-0.00.50.50.6-0.60.7
Locomotion distance, session 70.70.91.30.81.1-0.90.91.10.71.00.91.1-0.91.1
Stereotopy head waving bouts, day 70.10.10.2-0.1-0.40.3-0.3-0.4-0.0-0.4-0.3-0.30.4-0.4
Stereotopy head waving duration, day 70.20.30.4-0.2-0.60.5-0.5-0.6-0.1-0.6-0.4-0.40.5-0.6
Locomotion velocity, session 80.00.00.0-0.10.20.00.10.2-0.0-0.00.10.0-0.00.2
Locomotion distance, session 80.61.01.20.91.1-0.80.91.10.90.91.11.0-1.01.1
Degree of sensitization distance1.61.61.81.21.4-1.21.21.41.21.31.21.3-1.21.4
Degree of sensitization stereotypy0.10.10.1-0.1-0.30.2-0.2-0.3-0.2-0.3-0.2-0.10.2-0.3
Condit. Reinf. active minus inactive responses0.50.63.21.10.4-0.40.40.41.80.40.70.6-0.40.4
Condit. Reinf. active-inactive response ratio0.40.42.81.00.1-0.10.10.11.70.10.40.3-0.20.1
Condit. Reinf. active responses0.30.42.00.90.4-0.30.30.41.40.30.60.5-0.40.4
Condit. Reinf. inactive responses0.50.60.80.80.8-0.60.60.80.70.80.80.9-0.80.8
Incentive salience index mean0.10.11.00.50.10.0-0.00.01.0-0.00.20.2-0.00.0
Condit. Reinf. lever presses0.30.40.6-0.5-0.70.8-0.7-0.7-0.2-0.7-0.6-0.60.7-0.7
Time in familiar zone, hab. session 10.10.10.70.50.1-0.00.10.10.80.10.3-0.0-0.00.1
Time in novel zone, hab. session 11.31.31.7-1.2-1.21.0-1.1-1.2-1.3-1.1-1.2-1.01.0-1.2
Total zone transitions, hab. session 10.10.20.4-0.7-0.20.3-0.3-0.2-0.6-0.4-0.4-0.50.4-0.2
Total locomotion distance, hab. session 10.71.11.30.81.1-1.11.11.10.71.11.01.0-1.01.1
Locomotion velocity, hab. session 10.60.91.10.61.0-1.01.01.00.51.00.90.9-0.91.0
Time in familiar zone, hab. session 20.50.50.7-0.7-0.60.8-0.9-0.6-0.5-0.8-0.7-0.80.8-0.6
Time in novel zone, hab. session 20.10.10.10.30.0-0.20.30.00.30.20.20.2-0.30.0
Total zone transitions, hab. session 20.50.60.80.70.9-0.70.70.90.90.70.90.7-0.70.9
Total locomotion distance, hab. session 21.82.43.11.61.6-1.51.41.61.81.41.61.4-1.41.6
Locomotion velocity, hab. session 21.52.12.51.41.5-1.41.31.51.61.31.51.3-1.31.5
Novel to familiar place preference ratio0.10.10.20.40.1-0.30.30.10.40.30.30.2-0.30.1
Novelty place preference0.10.10.20.40.1-0.20.20.10.40.20.20.1-0.20.1
Time in novel zone, NPP test0.00.00.10.2-0.10.00.0-0.10.30.00.1-0.1-0.0-0.1
Total zone transitions, NPP test0.50.71.40.90.9-0.70.70.91.20.70.90.7-0.60.9
Total locomotion distance, NPP test0.81.11.41.01.2-1.01.01.21.01.01.11.0-1.01.2
Locomotion velocity, NPP test1.11.62.01.11.4-1.31.31.41.11.21.31.2-1.21.4
Pavlov. Cond. lever latency0.30.40.50.50.7-0.60.60.70.30.70.50.7-0.70.7
Pavlov. Cond. magazine entry latency0.10.10.2-0.2-0.30.4-0.4-0.3-0.0-0.4-0.2-0.40.3-0.3
Pavlov. Cond. change in total contacts0.30.30.60.70.5-0.50.50.50.80.50.60.5-0.50.5
Pavlov. Cond. index score0.10.20.3-0.3-0.40.5-0.5-0.4-0.1-0.5-0.3-0.50.5-0.4
Pavlov. Cond. latency score0.20.30.4-0.4-0.50.6-0.6-0.5-0.2-0.7-0.4-0.70.6-0.5
Pavlov. Cond. lever contacts0.10.20.2-0.3-0.40.4-0.4-0.4-0.2-0.5-0.3-0.50.4-0.4
Pavlov. Cond. magazine entry number0.70.91.00.81.0-1.01.01.00.51.00.91.0-1.01.0
Pavlov. Cond. intertrial magazine entries0.60.81.61.00.8-0.70.70.81.30.70.90.8-0.70.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.1-0.10.1-0.1-0.10.3-0.10.0-0.10.1-0.1
Pavlov. Cond. response bias0.10.10.2-0.2-0.40.3-0.3-0.4-0.1-0.4-0.3-0.30.3-0.4
Bone: apparent density5.18.49.0-2.9-2.92.9-2.9-2.9-2.8-2.9-3.0-3.02.9-2.9
Bone surface0.40.61.5-1.0-0.60.7-0.7-0.6-1.2-0.7-0.9-0.70.7-0.6
Bone volume2.13.64.4-2.1-1.81.9-1.9-1.8-2.1-1.9-2.0-1.91.8-1.8
Bone: connectivity density1.11.62.2-1.4-1.21.2-1.2-1.2-1.5-1.3-1.4-1.31.2-1.2
Bone: cortical apparent density2.02.63.31.31.6-1.81.81.60.81.81.41.8-1.81.6
Bone: cortical area0.20.20.30.40.5-0.50.50.50.30.50.50.5-0.60.5
Bone: cortical porosity1.61.71.9-1.3-1.41.3-1.3-1.4-1.2-1.3-1.4-1.31.2-1.4
Bone: cortical porosity1.92.02.2-1.4-1.51.5-1.5-1.5-1.1-1.5-1.4-1.51.4-1.5
Bone: cortical thickness0.30.40.50.60.6-0.70.70.60.50.70.60.7-0.70.6
Bone: cortical thickness0.10.10.10.30.4-0.30.30.40.30.30.30.2-0.30.4
Bone: cortical tissue density1.92.43.11.31.6-1.71.71.60.81.81.41.7-1.71.6
Bone: elastic displacement0.60.71.1-1.0-0.70.8-0.8-0.7-1.0-0.8-0.9-0.90.8-0.7
Bone: elastic work0.40.50.7-0.7-0.60.7-0.7-0.6-0.5-0.8-0.7-0.80.8-0.6
Bone: endosteal estimation0.00.00.0-0.1-0.20.1-0.1-0.2-0.1-0.1-0.2-0.10.1-0.2
Bone: endosteal perimeter0.00.00.10.20.1-0.00.00.10.3-0.10.2-0.10.10.1
Bone: final force0.20.30.40.70.3-0.60.60.30.50.60.40.5-0.60.3
Bone: final moment0.20.30.40.60.3-0.60.60.30.50.60.40.6-0.70.3
Bone: marrow area0.00.00.0-0.0-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.1
Bone: maximum diameter0.00.10.1-0.3-0.10.3-0.3-0.1-0.3-0.2-0.2-0.30.2-0.1
Bone: maximum force0.20.30.40.70.5-0.60.60.50.60.60.60.6-0.70.5
Bone: maximum moment0.20.30.50.60.5-0.60.60.50.50.60.50.6-0.70.5
Bone: minimum diameter0.40.71.00.70.7-0.90.90.70.40.90.71.0-1.00.7
Bone: periosteal estimation0.00.00.00.0-0.10.0-0.0-0.1-0.0-0.0-0.1-0.0-0.0-0.1
Bone: periosteal perimeter0.00.00.10.30.1-0.20.20.10.30.10.30.1-0.10.1
Bone: post-yield work0.20.20.3-0.3-0.50.5-0.5-0.5-0.4-0.5-0.4-0.40.4-0.5
Bone: stiffness0.20.30.50.70.3-0.60.60.30.70.60.40.6-0.70.3
Bone: tissue strength0.20.20.40.60.3-0.50.50.30.60.60.30.6-0.60.3
Bone: trabecular number4.06.26.6-2.5-2.42.5-2.5-2.4-2.4-2.6-2.5-2.62.5-2.4
Bone: trabecular spacing3.24.14.52.12.0-2.02.02.02.12.02.12.0-2.12.0
Bone: trabecular thickness5.76.97.4-2.5-2.72.7-2.7-2.7-2.2-2.7-2.6-2.72.7-2.7
Bone: trabecular tissue density0.20.20.3-0.3-0.50.5-0.5-0.5-0.2-0.5-0.4-0.50.5-0.5
Breakpoint value in progressive ratio session0.20.20.3-0.4-0.50.5-0.5-0.4-0.2-0.5-0.4-0.40.5-0.4
Distance traveled before self-admin0.10.10.3-0.5-0.10.4-0.4-0.0-0.4-0.4-0.4-0.50.4-0.1
Distance traveled after self-admin3.33.64.1-2.0-1.71.9-1.9-1.7-1.9-2.0-1.9-2.02.0-1.8
Delta time in closed arm before/after self-admin1.11.02.8-1.4-1.00.8-0.8-0.9-1.7-0.8-1.1-0.80.7-0.8
Delta time in open arm before/after self-admin0.10.10.2-0.1-0.40.4-0.3-0.40.0-0.4-0.0-0.20.4-0.2
Diff in mean of infusions in LGA sessions1.11.21.8-1.1-1.31.0-1.0-1.3-1.2-1.1-1.1-0.91.0-1.3
Extinction: sum of active levers before priming0.00.00.20.20.2-0.20.00.30.4-0.10.2-0.20.10.2
Active lever presses in extinction session 61.61.62.51.51.0-1.31.30.91.61.11.31.2-1.11.3
Delta distance traveled before/after self-admin0.80.91.4-0.9-1.00.8-0.8-1.0-1.2-0.9-0.9-0.80.9-1.1
Delta ambulatory time before/after self-admin0.70.71.4-1.0-0.80.7-0.7-0.8-1.2-0.8-0.9-0.60.7-1.0
Time in closed arm before self-admin0.20.20.70.80.2-0.20.30.10.80.30.40.2-0.30.0
Time in closed arm after self-admin0.90.91.5-1.0-1.20.8-0.8-1.2-1.2-0.7-1.0-0.80.7-1.1
Time in open arm before self-admin0.40.40.80.30.8-0.60.60.90.30.60.50.6-0.70.7
Time in open arm after self-admin0.30.30.6-0.6-0.30.7-0.7-0.3-0.3-0.7-0.4-0.60.7-0.2
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.30.4-0.4-0.2-0.3-0.5-0.4-0.60.6-0.4
Time to tail flick, vehicle, before self-admin0.20.20.40.60.5-0.40.40.50.60.30.60.3-0.30.5
Time to tail flick, vehicle, after self-admin0.00.00.20.3-0.10.0-0.0-0.00.4-0.00.0-0.10.0-0.0
Time to tail flick, test, before self-admin0.70.71.01.00.7-0.80.80.70.80.81.00.7-0.80.9
Time to tail flick, test, after self-admin2.42.53.11.71.5-1.61.61.41.61.51.61.7-1.51.6
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.2-0.30.2-0.2-0.3-0.2-0.2-0.4-0.20.2-0.3
Delta time to tail flick, test, before/after SA0.10.10.20.30.3-0.40.30.30.30.30.20.5-0.30.3
Ambulatory time before self-admin0.00.00.1-0.10.30.2-0.20.20.1-0.10.0-0.20.20.3
Ambulatory time after self-admin0.60.61.5-1.1-0.50.8-0.7-0.5-1.2-0.8-0.7-0.80.8-0.6
Total heroin consumption0.10.10.20.40.1-0.30.20.10.40.30.20.5-0.3-0.1
Area under the delay curve0.40.41.40.90.5-0.40.40.51.20.50.80.4-0.40.5
Delay disc. indifference point, 0s delay0.10.10.30.30.0-0.50.50.0-0.20.50.40.4-0.50.2
Delay disc. indifference point, 16s delay0.10.10.70.20.10.5-0.40.10.8-0.40.2-0.40.4-0.0
Delay disc. indifference point, 2s delay0.20.20.40.50.1-0.50.50.10.10.60.50.6-0.50.3
Delay disc. indifference point, 24s delay0.20.20.4-0.0-0.60.5-0.4-0.60.1-0.4-0.3-0.50.4-0.6
Delay disc. indifference point, 4s delay0.70.81.31.00.8-0.80.80.81.10.81.00.8-0.80.8
Delay disc. indifference point, 8s delay0.10.10.30.40.1-0.10.10.10.50.10.30.1-0.10.2
Delay discount exponential model param0.30.31.4-0.9-0.40.3-0.4-0.4-1.2-0.4-0.7-0.40.3-0.4
Delay discount hyperbolic model param0.60.61.6-1.1-0.60.6-0.6-0.6-1.3-0.7-0.9-0.60.6-0.6
Fecal boli incidents, locomotor time 12.93.23.81.81.8-1.81.71.81.81.71.81.7-1.82.0
Change in fecal boli incidents, locomotor task0.30.30.9-0.6-0.70.3-0.3-0.7-0.9-0.3-0.6-0.30.3-0.6
Time >=10cm from walls, locomotor time 12.02.03.21.21.4-1.31.51.61.01.41.51.4-1.41.8
Bouts of movement, locomotor time 110.311.413.03.53.4-3.43.23.53.63.33.33.3-3.23.3
Total resting periods, locomotor time 110.411.612.53.53.4-3.43.33.53.53.43.33.4-3.33.4
Rest time, locomotor task time 11.51.63.11.31.5-1.01.01.51.81.01.31.0-1.01.3
Distance moved, locomotor task time 10.50.51.8-0.8-0.90.4-0.4-0.8-1.3-0.4-0.8-0.40.4-0.8
Vertical activity count, locomotor time 11.71.82.4-1.5-1.31.3-1.3-1.3-1.5-1.3-1.3-1.31.2-1.4
Time >=10cm from walls, locomotor time 20.00.00.1-0.10.20.10.10.3-0.1-0.00.1-0.0-0.00.2
Bouts of movement, locomotor time 23.74.05.51.82.3-1.81.82.42.01.81.91.8-1.92.2
Total resting periods, locomotor time 23.23.55.21.62.2-1.81.72.31.71.71.71.7-1.82.1
Rest time, locomotor task time 20.00.10.1-0.3-0.10.2-0.2-0.1-0.1-0.2-0.3-0.20.2-0.2
Distance moved, locomotor task time 20.20.20.40.40.1-0.50.60.1-0.20.60.30.6-0.60.1
Vertical activity count, locomotor time 20.50.51.10.80.9-0.50.50.81.10.50.80.5-0.60.7
Weight adjusted by age0.30.30.50.20.7-0.40.40.7-0.40.60.70.6-0.30.7
Seeking ratio, delayed vs. immediate footshock0.10.20.4-0.2-0.30.7-0.5-0.30.1-0.5-0.3-0.50.5-0.2
Locomotion in novel chamber7.49.210.82.93.1-3.03.03.12.83.13.33.0-3.13.0
Locomotion in novel chamber post-restriction4.55.47.02.12.6-2.22.12.62.22.22.52.2-2.12.6
Progressive ratio3.03.55.92.11.8-1.81.81.82.41.71.81.8-1.71.7
Food seeking constrained by brief footshock0.00.00.00.10.1-0.00.00.10.10.00.10.20.00.0
Seeking ratio, punishment vs. effort1.51.83.2-1.6-1.21.4-1.3-1.2-1.8-1.2-1.3-1.31.2-1.1
Run reversals in cocaine runway, females1.11.02.00.81.4-0.70.81.41.40.70.90.8-0.71.2
Run reversals in cocaine runway, males0.60.61.00.71.0-0.60.61.00.80.80.80.7-0.60.9
Latency to leave start box in cocaine runway2.83.03.61.51.9-1.71.81.91.51.71.71.6-1.81.9
Latency to leave start box in cocaine runway, F0.20.20.5-0.10.7-0.30.40.70.00.30.40.3-0.30.7
Latency to leave start box in cocaine runway, M5.25.06.32.32.0-2.52.52.02.02.42.12.3-2.52.0
Cd content in liver0.10.10.1-0.3-0.20.3-0.3-0.2-0.1-0.3-0.3-0.20.3-0.2
Co content in liver0.30.40.50.0-0.70.7-0.7-0.70.6-0.7-0.5-0.70.7-0.7
Cu content in liver0.40.50.8-0.2-0.80.9-0.9-0.80.3-0.8-0.6-0.80.8-0.8
Fe content in liver2.73.23.9-1.7-1.81.8-1.8-1.8-1.4-1.9-1.8-2.01.9-1.8
K content in liver0.90.91.20.61.0-1.11.11.00.11.00.91.1-1.11.0
Mg content in liver0.10.10.20.10.4-0.40.40.4-0.20.40.20.4-0.40.4
Mn content in liver0.20.20.30.40.4-0.50.50.40.20.40.50.5-0.50.4
Na content in liver1.41.43.9-1.5-1.01.0-1.0-1.0-2.0-1.0-1.2-1.11.0-1.0
Rb content in liver3.64.55.72.22.1-2.02.02.12.42.12.22.1-2.02.1
Se content in liver0.30.40.60.60.8-0.60.60.80.50.60.70.6-0.60.7
Sr content in liver0.00.00.00.10.1-0.10.10.10.10.10.10.1-0.10.1
Zn content in liver0.00.00.10.2-0.00.1-0.1-0.00.4-0.20.0-0.10.1-0.0