Hub : Genes

Poldip3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000022877 0.05 0.04 1.4e-05 0.03 0.03 0.03 0.03 3.7e-04 1.4e-04 2.8e-04 4.2e-04
2 BLA intron excision ratio chr7:114284426:114287502 0.07 0.05 8.1e-04 0.03 0.04 0.04 0.03 7.6e-03 4.3e-03 5.9e-03 6.6e-03
3 Brain gene expression ENSRNOG00000022877 0.03 0.02 4.8e-04 0.02 0.02 0.01 0.02 2.8e-03 7.5e-03 3.1e-02 5.9e-03
4 Brain intron excision ratio chr7:114284426:114287502 0.03 0.02 2.0e-04 0.02 0.03 0.01 0.02 3.3e-03 7.7e-04 2.2e-02 6.0e-03
5 NAcc isoform ratio ENSRNOT00000055988 0.03 0.02 3.2e-03 0.03 0.02 0.02 0.02 2.4e-03 1.2e-02 2.1e-02 8.8e-03
6 NAcc isoform ratio ENSRNOT00000082524 0.03 0.02 7.1e-03 0.03 0.01 0.01 0.02 5.1e-03 2.8e-02 6.6e-02 1.9e-02
7 NAcc intron excision ratio chr7:114284426:114287502 0.05 0.04 4.5e-04 0.03 0.04 0.03 0.03 3.5e-03 1.2e-03 1.4e-03 1.6e-03
8 PL intron excision ratio chr7:114284426:114287502 0.08 0.05 2.5e-06 0.07 0.07 0.06 0.06 8.0e-06 9.0e-06 5.3e-05 3.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.55.05.5-2.3-2.2-2.3-2.3-2.22.2-2.0-2.4
BMI without tail0.40.81.2-0.8-1.0-1.1-0.7-0.90.9-0.9-1.1
Body weight1.66.77.4-2.7-2.7-2.7-2.6-2.62.6-2.7-2.0
Epididymis fat weight1.74.16.4-2.0-2.1-1.7-1.9-2.12.1-2.5-1.5
Glucose0.50.81.00.91.00.90.80.9-0.91.00.9
Heart weight2.63.75.2-2.3-2.1-1.7-2.2-1.81.8-1.6-1.5
Left kidney weight15.845.348.0-6.8-6.8-6.9-6.8-6.96.9-6.8-5.7
Right kidney weight16.647.351.2-7.0-6.9-7.2-7.0-7.07.0-6.8-6.2
Tail length0.00.10.30.3-0.00.10.30.1-0.1-0.00.5
Length with tail0.41.32.1-1.1-1.2-1.1-1.1-1.21.2-1.5-0.2
Length without tail0.61.42.0-1.2-1.1-1.2-1.4-1.31.3-1.3-0.4
Liver weight, left0.30.51.3-0.6-0.7-0.8-0.5-0.80.8-1.1-0.2
Liver weight, right0.81.33.2-1.0-1.1-1.2-0.9-1.21.2-1.8-0.2
Parametrial fat weight0.10.10.30.10.30.40.10.4-0.40.40.6
Retroperitoneal fat weight1.75.67.3-2.5-2.3-2.4-2.5-2.52.5-2.7-1.3
Intraocular pressure0.20.30.9-0.6-0.6-0.4-0.5-0.40.4-0.6-0.9
Extensor digitorum longus weight0.00.10.30.1-0.00.50.20.5-0.50.1-0.2
Soleus weight0.00.10.4-0.1-0.1-0.0-0.1-0.00.00.2-0.6
Tibialis anterior weight0.62.13.21.11.21.81.21.7-1.71.71.2
Tibia length1.13.03.4-1.7-1.8-1.6-1.9-1.81.8-1.8-1.2
Number of licking bursts0.20.30.60.40.40.80.50.6-0.60.40.3
Food consumed during 24 hour testing period2.02.43.4-1.6-1.6-1.4-1.7-1.31.3-1.5-1.8
Times rat made contact with spout1.11.32.3-1.3-1.2-1.1-1.2-0.90.9-0.9-1.5
Mean time between licks in bursts0.81.21.41.01.10.91.11.1-1.11.20.9
Mean num. licks in bursts1.82.22.9-1.5-1.4-1.7-1.4-1.41.4-1.4-1.5
Std. dev. time between licks in bursts0.50.61.20.80.80.50.60.6-0.61.01.1
Water consumed over 24 hours3.13.66.3-1.9-2.0-1.9-1.8-1.61.6-1.7-2.5
Indifference point 0 sec0.10.20.50.30.30.70.10.4-0.40.60.4
Indifference point AUC0.10.10.20.30.30.50.30.1-0.10.40.2
Indifference point function ln k1.01.41.8-1.3-1.3-1.2-1.3-1.01.0-1.3-1.0
Indifference point function log k1.01.41.8-1.3-1.3-1.2-1.3-1.01.0-1.3-1.0
Delay discounting total patch changes 0 sec0.20.30.70.40.50.80.30.6-0.60.70.4
Delay discounting total patch changes 12 sec0.10.10.3-0.2-0.2-0.1-0.4-0.60.6-0.1-0.5
Delay discounting total patch changes 18 sec0.00.10.10.00.1-0.1-0.2-0.30.30.30.3
Delay discounting total patch changes 24 sec0.20.20.50.40.40.70.40.5-0.50.50.2
Delay discounting total patch changes 6 sec0.00.00.1-0.2-0.10.2-0.3-0.20.20.2-0.1
Delay discounting time to switch 0 sec0.10.20.50.70.6-0.10.6-0.00.00.30.7
Delay discounting water rate 0 sec0.30.41.5-0.8-0.8-0.1-0.7-0.10.1-0.3-1.2
Delay discounting water rate 12 sec0.10.21.1-0.2-0.4-0.4-0.20.0-0.0-0.2-1.1
Delay discounting water rate 18 sec0.10.10.20.40.20.30.30.3-0.30.30.1
Delay discounting water rate 24 sec1.72.43.4-1.4-1.6-1.8-1.5-1.51.5-1.3-1.5
Delay discounting water rate 6 sec0.20.30.50.70.50.50.60.4-0.40.40.4
Locomotor activity3.04.85.6-2.1-2.3-2.3-2.1-2.42.4-2.4-1.6
Locomotor testing distance0.00.00.10.10.1-0.10.1-0.10.1-0.00.3
Locomotor testing rearing0.61.01.6-1.1-1.0-0.8-0.9-1.11.1-1.3-0.6
Light reinforcement 10.40.81.3-0.6-0.8-1.0-0.6-1.11.1-1.1-0.5
Light reinforcement 20.60.81.7-0.6-0.7-1.3-0.7-0.90.9-1.0-0.7
Reaction time number correct1.31.92.51.51.31.21.61.4-1.41.01.5
Reaction time mean minus median0.20.30.5-0.7-0.7-0.1-0.4-0.40.4-0.6-0.7
Reaction time mean minus median AUC0.50.71.5-0.9-0.9-0.5-0.7-0.60.6-0.8-1.2
Reaction time num false alarms0.10.10.4-0.1-0.4-0.30.0-0.30.3-0.70.1
Reaction time num false alarms AUC0.10.10.4-0.1-0.4-0.30.0-0.30.3-0.70.1
Reaction time trials correct on left1.31.92.51.51.31.21.61.4-1.41.01.5
Reaction time trials on left1.42.02.71.61.31.21.61.4-1.41.01.5
Reaction time mean0.00.00.10.20.10.10.20.0-0.00.30.0
Reaction time mean AUC0.00.00.10.20.20.00.30.0-0.00.30.0
Median of all reaction times0.10.10.30.50.40.20.40.2-0.20.60.3
Reaction time omissions0.10.10.30.40.30.40.60.3-0.30.30.3
Reaction time false alarm rate0.40.60.8-0.8-0.9-0.6-0.7-0.70.7-0.9-0.6
Reaction time premature initiation rate0.10.10.30.0-0.0-0.4-0.3-0.60.60.10.1
Reaction time premature initiations0.10.20.50.60.50.20.40.1-0.10.50.7
Std. dev. reaction times0.40.50.8-0.8-0.9-0.6-0.7-0.80.8-0.8-0.5
Reaction time trials completed1.42.02.71.61.31.21.61.4-1.41.01.5
Reaction time trials AUC1.01.41.91.31.11.01.41.2-1.20.81.3
Social response proportion0.20.20.5-0.6-0.4-0.4-0.6-0.40.4-0.1-0.7
Social responses0.00.10.10.0-0.1-0.00.0-0.30.3-0.30.4
Social time2.12.73.01.71.71.61.61.6-1.61.71.5
Conditioned locomotion0.20.20.5-0.4-0.4-0.4-0.2-0.60.6-0.7-0.1
Cocaine response after cond. corrected0.00.00.0-0.0-0.10.20.0-0.20.2-0.20.0
Cocaine response after cond. not corrected0.00.00.1-0.1-0.10.10.0-0.20.2-0.3-0.2
Cocaine response before conditioning0.10.10.20.20.30.10.20.4-0.40.20.1
Saline control response0.30.40.9-0.5-0.7-0.6-0.4-0.70.7-1.0-0.4
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.3-0.5-0.6-0.60.6-0.1-0.1
Condit. Reinf. active-inactive response ratio0.30.30.6-0.4-0.4-0.7-0.8-0.80.8-0.1-0.0
Condit. Reinf. active responses1.11.51.9-1.1-1.1-1.3-1.3-1.41.4-1.1-1.0
Condit. Reinf. inactive responses1.01.21.7-1.1-1.1-1.0-1.0-1.11.1-1.3-1.2
Condit. Reinf. lever presses0.00.00.10.20.30.2-0.00.1-0.10.40.2
Condit. Reinf. lever reinforcers received0.40.61.0-0.7-0.7-0.8-0.9-1.01.0-0.6-0.4
Pavlov. Cond. lever latency0.10.10.3-0.4-0.4-0.3-0.1-0.10.1-0.5-0.5
Pavlov. Cond. magazine entry latency3.03.55.71.92.02.01.51.6-1.62.41.7
Pavlov. Cond. change in total contacts0.10.20.50.20.40.1-0.3-0.20.20.70.6
Pavlov. Cond. index score1.21.62.91.31.41.30.91.0-1.01.71.3
Pavlov. Cond. latency score1.62.03.71.41.61.51.01.2-1.21.91.4
Pavlov. Cond. lever contacts0.10.10.30.50.50.30.10.1-0.10.60.5
Pavlov. Cond. magazine entry number1.62.03.4-1.4-1.6-1.7-1.0-1.11.1-1.8-1.4
Pavlov. Cond. intertrial magazine entries2.12.73.9-2.0-1.8-1.8-1.8-1.31.3-1.5-1.7
Pavlov. Cond. lever-magazine prob. diff.1.41.83.01.41.51.31.01.0-1.01.71.4
Pavlov. Cond. response bias0.30.40.90.70.80.60.30.3-0.30.90.8
Conditioned reinforcement - actives0.10.10.4-0.00.00.2-0.0-0.00.0-0.10.6
Conditioned reinforcement - inactives0.10.10.20.10.30.30.00.3-0.30.50.2
Conditioned locomotion0.91.11.4-1.2-1.0-1.1-1.2-1.11.1-1.0-0.6
Intermittent access intake day 1-15 change0.40.40.70.60.70.50.60.5-0.50.70.8
Intermittent access intake escalation0.30.30.40.60.60.40.60.5-0.50.70.7
Intermittent access intake escalation 20.10.10.10.30.30.20.30.2-0.20.30.3
Intermitt. access day 1 inactive lever presses0.80.81.2-1.0-0.8-0.8-1.1-1.01.0-0.5-1.1
Intermitt. access day 15 inactive lever presses0.70.81.6-1.1-0.8-0.8-1.2-0.80.8-0.4-0.8
Intermitt. access escalation Index0.10.10.20.20.30.30.10.2-0.20.40.3
Intermittent access day 1 total infusions0.60.71.0-0.9-0.8-0.9-1.0-0.90.9-0.7-0.6
Intermittent access day 15 total infusions0.00.00.0-0.1-0.1-0.2-0.2-0.10.10.1-0.1
Intermittent access terminal intake (last 3 days)0.00.00.0-0.00.00.1-0.0-0.10.10.0-0.1
Intermittent access total infusions0.10.10.1-0.4-0.3-0.3-0.4-0.20.2-0.2-0.4
Intermittent access day 1 locomotion0.10.10.2-0.3-0.2-0.4-0.4-0.30.3-0.10.1
Intermittent access day 15 total locomotion0.10.10.2-0.2-0.2-0.5-0.2-0.30.3-0.1-0.3
Intermittent access total locomotion0.10.10.3-0.4-0.2-0.5-0.5-0.30.3-0.1-0.6
Intermittent access standard deviation0.40.50.6-0.7-0.6-0.8-0.8-0.80.8-0.4-0.6
Cocaine induced anxiety1.82.04.8-1.4-1.3-1.4-1.5-1.21.2-1.0-2.2
Post-drug Anxiety1.31.52.8-1.1-1.2-1.3-1.2-1.11.1-0.9-1.7
Baseline Anxiety1.51.63.81.31.11.21.31.1-1.10.92.0
Lifetime Intake0.40.40.7-0.8-0.6-0.6-0.9-0.50.5-0.4-0.8
Incentive Sensitization - Responses0.20.21.1-0.2-0.1-0.3-0.30.1-0.10.2-1.0
Incentive Sensitization - Breakpoint0.20.21.3-0.3-0.3-0.4-0.5-0.10.10.1-1.1
Progressive ratio test 1 active lever presses0.10.10.2-0.3-0.2-0.3-0.4-0.40.4-0.00.2
Progressive ratio test 1 breakpoint0.00.00.3-0.00.2-0.0-0.1-0.10.10.20.6
Progressive ratio test 1 inactive lever presses0.10.10.3-0.4-0.0-0.1-0.5-0.30.30.3-0.2
Progressive ratio test 2 active lever presses0.00.00.1-0.00.1-0.1-0.20.1-0.10.4-0.3
Progressive ratio test 2 breakpoint0.10.10.2-0.2-0.1-0.3-0.4-0.10.10.2-0.3
Progressive ratio test 2 inactive lever presses0.10.10.50.10.30.3-0.10.4-0.40.7-0.0
Total sessions with >9 infusions0.70.81.4-1.1-0.9-0.8-1.2-0.90.9-0.8-0.5
Short access day 1 total inactive lever presses2.42.73.4-1.7-1.6-1.8-1.8-1.51.5-1.4-1.8
Short access day 10 total inactive lever presses2.22.53.9-1.5-1.6-1.5-1.4-1.51.5-1.5-2.0
Short access day 1 total infusions1.41.52.3-1.4-1.2-1.0-1.5-1.11.1-1.1-1.3
Short access day 10 total infusions0.10.10.4-0.2-0.0-0.1-0.3-0.10.1-0.00.6
Short access total infusions1.11.32.2-1.4-1.1-1.0-1.5-1.01.0-0.9-1.0
Short access day 1 locomotion0.00.00.10.00.30.1-0.00.2-0.20.3-0.2
Short access day 10 total locomotion0.60.71.00.81.00.70.80.7-0.70.91.0
Short access total locomotion0.10.10.2-0.4-0.1-0.4-0.5-0.40.4-0.10.3
Compulsive drug intake0.50.50.70.80.70.60.80.5-0.50.80.4
One hour access (0.3 mA shock)0.40.50.60.70.80.70.70.8-0.80.80.4
One hour access (shock baseline)0.30.40.70.50.60.70.50.8-0.80.50.3
Number of responses in last shaping day0.80.81.40.81.00.80.60.8-0.81.21.0
Context. condit. distance diff. score5.16.27.9-2.7-2.7-2.2-2.5-2.12.1-2.8-2.7
Locomotion velocity, session 11.01.11.8-0.7-1.0-1.4-0.7-1.11.1-1.2-1.0
Locomotion distance, session 10.70.91.51.20.90.91.21.0-1.00.80.3
Locomotion velocity, session 21.01.11.5-0.8-1.0-1.1-0.9-1.11.1-1.2-1.2
Locomotion distance, session 21.31.93.21.61.61.11.41.2-1.21.81.1
Locomotion velocity, session 30.50.61.3-0.4-0.7-0.8-0.4-0.60.6-1.0-1.1
Locomotion distance, session 31.51.72.41.31.21.51.41.6-1.61.00.6
Stereotopy head waving bouts, day 31.41.72.7-1.1-1.1-1.7-1.2-1.41.4-1.3-1.0
Stereotopy head waving duration, day 36.27.510.5-2.5-2.6-3.2-2.5-2.92.9-2.8-2.4
Locomotion velocity, session 70.00.00.10.20.10.20.20.0-0.0-0.2-0.3
Locomotion distance, session 71.11.41.91.21.41.31.11.2-1.21.30.9
Stereotopy head waving bouts, day 76.37.19.3-2.3-2.7-3.1-2.2-2.82.8-3.0-2.2
Stereotopy head waving duration, day 73.94.86.7-1.9-2.2-2.5-1.8-2.32.3-2.6-1.8
Locomotion velocity, session 86.57.88.6-2.7-2.8-2.9-2.6-2.92.9-2.6-2.9
Locomotion distance, session 80.91.31.7-1.2-1.2-1.1-1.1-1.01.0-1.3-1.3
Degree of sensitization distance1.21.21.8-1.2-0.9-1.1-1.3-1.31.3-0.8-0.8
Degree of sensitization stereotypy3.94.25.9-1.8-2.2-2.2-1.7-2.12.1-2.4-1.9
Condit. Reinf. active minus inactive responses0.70.82.30.91.10.70.70.5-0.51.01.5
Condit. Reinf. active-inactive response ratio0.30.30.7-0.3-0.3-0.7-0.4-0.80.8-0.40.1
Condit. Reinf. active responses2.83.55.01.82.01.81.61.6-1.62.02.2
Condit. Reinf. inactive responses4.45.16.12.12.32.52.12.4-2.42.42.0
Incentive salience index mean1.61.93.71.31.51.31.11.0-1.01.51.9
Condit. Reinf. lever presses1.72.33.81.61.71.51.41.2-1.21.61.9
Time in familiar zone, hab. session 10.10.10.3-0.2-0.3-0.5-0.1-0.30.3-0.4-0.4
Time in novel zone, hab. session 11.21.11.5-1.2-1.2-0.8-1.0-1.01.0-1.0-1.1
Total zone transitions, hab. session 12.23.13.81.91.71.72.01.8-1.81.61.6
Total locomotion distance, hab. session 10.40.61.21.00.70.51.10.7-0.70.30.7
Locomotion velocity, hab. session 10.71.01.71.31.00.81.21.0-1.00.60.9
Time in familiar zone, hab. session 20.10.10.30.30.20.20.60.3-0.3-0.20.4
Time in novel zone, hab. session 20.80.81.3-0.9-0.9-0.8-1.1-0.80.8-0.5-1.1
Total zone transitions, hab. session 20.10.10.20.50.40.20.30.3-0.30.40.0
Total locomotion distance, hab. session 20.20.30.30.60.50.50.50.6-0.60.50.3
Locomotion velocity, hab. session 20.50.70.90.90.80.90.80.9-0.90.80.6
Novel to familiar place preference ratio3.63.74.8-2.1-2.2-1.8-1.9-1.81.8-2.0-1.7
Novelty place preference4.64.76.0-2.4-2.5-2.1-2.1-2.12.1-2.3-1.9
Time in novel zone, NPP test6.06.37.8-2.7-2.8-2.4-2.4-2.42.4-2.6-2.3
Total zone transitions, NPP test0.91.31.71.31.11.11.31.2-1.21.00.7
Total locomotion distance, NPP test0.40.50.70.80.70.70.80.8-0.80.70.4
Locomotion velocity, NPP test1.42.02.41.61.41.51.51.5-1.51.31.2
Pavlov. Cond. lever latency2.22.74.8-1.7-1.8-1.6-1.5-1.31.3-1.7-2.2
Pavlov. Cond. magazine entry latency2.33.03.91.61.82.01.51.6-1.61.91.9
Pavlov. Cond. change in total contacts2.22.33.31.41.61.51.21.3-1.31.81.8
Pavlov. Cond. index score1.52.03.01.21.51.61.01.2-1.21.61.7
Pavlov. Cond. latency score1.21.52.61.11.31.40.91.0-1.01.41.6
Pavlov. Cond. lever contacts2.93.45.01.82.01.81.61.6-1.61.92.2
Pavlov. Cond. magazine entry number2.12.73.5-1.4-1.6-1.9-1.3-1.61.6-1.8-1.8
Pavlov. Cond. intertrial magazine entries0.50.61.00.70.70.80.60.8-0.81.00.6
Pavlov. Cond. lever-magazine prob. diff.2.22.73.71.51.71.81.31.5-1.51.81.9
Pavlov. Cond. response bias3.23.95.31.82.12.11.61.8-1.82.12.3
Bone: apparent density0.30.40.80.80.80.30.70.5-0.50.80.9
Bone surface0.10.20.70.0-0.2-0.9-0.1-0.70.7-0.30.2
Bone volume0.10.10.50.0-0.1-0.7-0.0-0.50.5-0.20.3
Bone: connectivity density0.10.10.30.40.4-0.10.30.1-0.10.50.5
Bone: cortical apparent density1.21.62.11.21.21.31.11.2-1.21.21.5
Bone: cortical area1.82.72.9-1.7-1.7-1.6-1.7-1.71.7-1.7-1.3
Bone: cortical porosity0.50.60.7-0.7-0.8-0.7-0.7-0.70.7-0.9-0.9
Bone: cortical porosity1.41.51.8-1.2-1.2-1.2-1.2-1.31.3-1.3-1.2
Bone: cortical thickness0.10.10.3-0.5-0.3-0.0-0.6-0.10.10.10.1
Bone: cortical thickness0.20.20.5-0.7-0.5-0.1-0.6-0.30.3-0.0-0.5
Bone: cortical tissue density1.11.41.91.11.21.21.01.2-1.21.21.4
Bone: elastic displacement1.21.42.0-1.0-1.3-1.4-0.9-1.21.2-1.3-1.2
Bone: elastic work4.55.96.6-2.4-2.5-2.5-2.3-2.62.6-2.3-2.3
Bone: endosteal estimation2.45.26.9-1.8-2.2-2.5-1.8-2.42.4-2.6-2.4
Bone: endosteal perimeter2.65.38.0-1.9-2.2-2.5-1.8-2.52.5-2.8-2.0
Bone: final force1.11.82.6-1.5-1.3-1.3-1.6-1.51.5-1.0-1.0
Bone: final moment1.72.83.6-1.8-1.6-1.6-1.9-1.81.8-1.3-1.4
Bone: marrow area2.75.87.5-2.0-2.3-2.6-1.9-2.52.5-2.7-2.5
Bone: maximum diameter6.011.012.1-3.3-3.4-3.4-3.2-3.43.4-3.5-3.1
Bone: maximum force2.95.05.9-2.3-2.2-2.2-2.4-2.42.4-2.0-2.0
Bone: maximum moment3.76.47.4-2.6-2.5-2.5-2.7-2.62.6-2.3-2.3
Bone: minimum diameter1.01.92.7-1.2-1.3-1.6-1.1-1.51.5-1.6-1.0
Bone: periosteal estimation3.16.37.7-2.3-2.5-2.6-2.2-2.72.7-2.8-2.3
Bone: periosteal perimeter4.37.19.5-2.5-2.7-2.8-2.4-2.82.8-3.1-2.3
Bone: post-yield work0.50.71.1-0.9-0.8-0.7-0.9-0.80.8-0.5-1.1
Bone: stiffness1.21.92.5-1.5-1.3-1.2-1.6-1.41.4-1.2-1.2
Bone: tissue strength0.50.50.7-0.6-0.7-0.6-0.7-0.90.9-0.6-0.6
Bone: trabecular number0.10.10.30.50.40.20.50.2-0.20.20.4
Bone: trabecular spacing0.81.11.3-1.1-1.0-1.0-1.2-1.01.0-0.9-1.0
Bone: trabecular thickness0.20.20.70.50.5-0.00.50.2-0.20.40.8
Bone: trabecular tissue density0.71.01.50.80.91.20.71.0-1.01.21.1
Breakpoint value in progressive ratio session0.10.10.1-0.2-0.3-0.2-0.3-0.30.3-0.1-0.1
Distance traveled before self-admin0.20.20.50.30.60.40.20.4-0.40.7-0.3
Distance traveled after self-admin0.20.30.9-0.5-0.4-0.3-0.6-0.30.3-0.2-1.0
Delta time in closed arm before/after self-admin0.10.10.3-0.5-0.2-0.3-0.5-0.40.4-0.30.0
Delta time in open arm before/after self-admin0.10.10.70.1-0.10.00.20.2-0.2-0.1-0.8
Diff in mean of infusions in LGA sessions0.80.91.30.91.10.80.90.7-0.71.11.1
Extinction: sum of active levers before priming0.10.20.40.20.30.70.20.3-0.30.40.6
Active lever presses in extinction session 60.40.40.5-0.6-0.6-0.5-0.7-0.70.7-0.6-0.7
Delta distance traveled before/after self-admin2.02.12.7-1.4-1.6-1.3-1.3-1.41.4-1.6-1.4
Delta ambulatory time before/after self-admin3.23.54.3-1.8-2.1-1.8-1.8-1.91.9-2.0-1.6
Time in closed arm before self-admin3.54.04.62.12.01.82.02.1-2.12.21.6
Time in closed arm after self-admin0.00.10.2-0.10.0-0.2-0.1-0.20.2-0.20.5
Time in open arm before self-admin0.10.10.20.30.30.30.40.3-0.30.00.4
Time in open arm after self-admin0.30.30.50.60.40.60.70.6-0.60.2-0.4
Sum of active levers in priming session hrs 5-60.00.00.10.10.10.20.1-0.10.10.1-0.2
Time to tail flick, vehicle, before self-admin0.40.40.6-0.5-0.6-0.6-0.5-0.80.8-0.7-0.2
Time to tail flick, vehicle, after self-admin0.30.31.00.80.50.51.00.3-0.30.30.4
Time to tail flick, test, before self-admin0.10.10.2-0.1-0.2-0.30.1-0.20.2-0.5-0.1
Time to tail flick, test, after self-admin3.03.13.81.61.71.91.71.9-1.91.61.6
Delta time to tail flick, vehicle, before/after SA0.10.10.10.30.30.10.30.2-0.20.4-0.2
Delta time to tail flick, test, before/after SA3.43.13.81.61.71.91.61.9-1.91.81.5
Ambulatory time before self-admin0.10.10.30.20.40.10.10.3-0.30.5-0.6
Ambulatory time after self-admin0.10.10.8-0.2-0.2-0.1-0.2-0.00.00.0-0.9
Total heroin consumption0.30.30.4-0.5-0.6-0.4-0.6-0.70.7-0.4-0.6
Area under the delay curve1.31.42.21.11.31.11.11.1-1.11.21.5
Delay disc. indifference point, 0s delay0.30.30.4-0.7-0.5-0.5-0.7-0.50.5-0.6-0.5
Delay disc. indifference point, 16s delay2.72.74.31.71.81.41.61.3-1.31.72.1
Delay disc. indifference point, 2s delay0.40.50.70.50.70.80.50.9-0.90.60.6
Delay disc. indifference point, 24s delay0.30.30.70.70.60.40.70.4-0.40.50.8
Delay disc. indifference point, 4s delay0.10.10.30.20.40.20.00.2-0.20.60.3
Delay disc. indifference point, 8s delay2.62.73.31.61.71.61.61.6-1.61.71.8
Delay discount exponential model param1.31.42.1-1.1-1.3-1.1-1.1-1.11.1-1.2-1.4
Delay discount hyperbolic model param0.91.01.4-0.9-1.1-0.9-0.9-0.90.9-1.0-1.2
Fecal boli incidents, locomotor time 10.30.30.50.50.50.70.50.6-0.60.50.2
Change in fecal boli incidents, locomotor task0.80.81.1-0.7-0.9-1.1-0.6-1.01.0-1.0-0.6
Time >=10cm from walls, locomotor time 10.00.00.00.10.1-0.10.0-0.10.10.0-0.0
Bouts of movement, locomotor time 10.00.10.10.20.30.10.30.1-0.10.30.2
Total resting periods, locomotor time 10.30.30.50.50.70.40.50.4-0.40.70.4
Rest time, locomotor task time 10.10.10.20.10.40.40.10.3-0.30.5-0.1
Distance moved, locomotor task time 10.40.40.8-0.6-0.6-0.8-0.6-0.60.6-0.90.0
Vertical activity count, locomotor time 10.10.10.2-0.2-0.3-0.4-0.3-0.30.3-0.30.1
Time >=10cm from walls, locomotor time 20.30.30.40.60.60.50.60.5-0.50.40.6
Bouts of movement, locomotor time 20.10.10.30.10.30.10.00.0-0.00.40.5
Total resting periods, locomotor time 20.10.10.30.10.30.1-0.0-0.00.00.40.6
Rest time, locomotor task time 20.20.20.30.40.50.50.30.4-0.40.50.4
Distance moved, locomotor task time 20.60.71.1-0.9-0.9-0.9-0.7-0.70.7-1.1-0.9
Vertical activity count, locomotor time 20.70.81.1-0.9-1.0-1.1-0.8-0.80.8-1.0-0.8
Weight adjusted by age0.10.10.3-0.2-0.4-0.4-0.1-0.30.3-0.5-0.3
Seeking ratio, delayed vs. immediate footshock3.74.25.72.12.12.01.92.4-2.42.21.1
Locomotion in novel chamber0.20.20.60.50.20.70.70.2-0.2-0.20.4
Locomotion in novel chamber post-restriction1.11.31.81.31.21.21.31.1-1.11.00.9
Progressive ratio0.00.00.10.10.10.2-0.00.0-0.00.30.2
Food seeking constrained by brief footshock1.11.31.6-1.2-1.1-1.1-1.2-1.31.3-1.2-0.7
Seeking ratio, punishment vs. effort0.30.40.5-0.6-0.6-0.7-0.6-0.60.6-0.7-0.5
Run reversals in cocaine runway, females1.21.22.11.31.11.01.30.9-0.90.71.4
Run reversals in cocaine runway, males1.11.11.4-1.0-1.2-0.8-0.9-1.01.0-1.2-1.2
Latency to leave start box in cocaine runway0.20.20.6-0.4-0.4-0.4-0.4-0.40.4-0.4-0.8
Latency to leave start box in cocaine runway, F0.20.20.30.50.50.60.50.5-0.50.4-0.1
Latency to leave start box in cocaine runway, M1.51.41.8-1.3-1.2-1.3-1.3-1.11.1-1.0-1.1
Cd content in liver1.51.62.4-1.5-1.5-1.0-1.1-1.11.1-1.4-1.3
Co content in liver0.40.51.0-1.0-0.9-0.4-0.8-0.40.4-0.6-0.8
Cu content in liver4.65.68.12.62.62.02.41.9-1.92.52.9
Fe content in liver0.60.71.2-0.6-0.7-1.1-0.6-1.11.1-0.8-0.6
K content in liver0.20.20.50.50.50.00.2-0.00.00.60.7
Mg content in liver0.60.61.10.91.00.30.50.3-0.31.11.1
Mn content in liver0.10.10.3-0.2-0.2-0.3-0.1-0.30.3-0.5-0.2
Na content in liver2.52.73.11.81.71.61.71.6-1.61.71.4
Rb content in liver0.20.30.6-0.2-0.2-0.8-0.3-0.80.8-0.10.0
Se content in liver0.70.91.91.11.00.71.00.6-0.60.71.4
Sr content in liver1.61.52.31.01.01.41.21.5-1.51.20.9
Zn content in liver0.70.81.21.00.90.91.00.8-0.80.81.1