Hub : Genes

Fam169b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000022822 0.1 0.05 3.2e-13 0.09 0.11 0.1 0.11 3.6e-10 1.8e-12 1.1e-10 8.4e-12
2 Adipose mRNA stability ENSRNOG00000022822 0.05 0.03 6.3e-06 0.05 0.05 0.04 0.05 1.6e-06 3.8e-06 4.0e-05 2.0e-06
3 BLA gene expression ENSRNOG00000022822 0.14 0.07 7.1e-07 0.1 0.1 0.1 0.11 5.3e-06 6.2e-06 4.0e-06 2.4e-06
4 BLA isoform ratio ENSRNOT00000040147 0.09 0.05 6.5e-04 0.05 0.05 0.03 0.05 1.2e-03 1.0e-03 1.2e-02 1.6e-03
5 BLA isoform ratio ENSRNOT00000119682 0.09 0.05 4.4e-04 0.06 0.06 0.04 0.05 6.7e-04 5.3e-04 3.6e-03 7.2e-04
6 BLA mRNA stability ENSRNOG00000022822 0.28 0.1 8.0e-12 0.21 0.19 0.2 0.2 1.5e-11 2.1e-10 1.0e-10 7.6e-11
7 Brain gene expression ENSRNOG00000022822 0.23 0.08 0.0e+00 0.26 0.24 0.27 0.27 2.1e-24 1.6e-22 5.1e-25 4.2e-25
8 Brain isoform ratio ENSRNOT00000040147 0.03 0.02 9.8e-03 0.02 0.01 0.01 0.02 5.1e-03 1.7e-02 6.3e-02 1.0e-02
9 Brain intron excision ratio chr1:121932527:121949181 0.02 0.02 9.5e-03 0.01 0.01 -0 0.01 5.4e-02 1.4e-02 7.4e-01 3.0e-02
10 Brain mRNA stability ENSRNOG00000022822 0.13 0.06 1.1e-13 0.18 0.11 0.16 0.17 1.1e-16 2.5e-10 4.8e-15 5.5e-16
11 IL gene expression ENSRNOG00000022822 0.3 0.15 6.0e-04 0.15 0.08 0.16 0.15 1.6e-04 5.6e-03 1.3e-04 1.8e-04
12 LHb gene expression ENSRNOG00000022822 0.32 0.13 3.5e-05 0.22 0.21 0.3 0.25 6.0e-06 8.2e-06 5.7e-08 1.1e-06
13 Liver gene expression ENSRNOG00000022822 0.59 0.11 0.0e+00 0.52 0.53 0.53 0.54 3.6e-67 5.0e-69 7.7e-69 5.5e-70
14 Liver intron excision ratio chr1:121879504:121899372 0.04 0.03 1.6e-04 0.04 0.02 0.01 0.03 2.8e-05 3.2e-03 1.7e-02 1.7e-04
15 Liver intron excision ratio chr1:121929167:121948528 0.04 0.02 1.7e-05 0.03 0.04 0.04 0.04 1.1e-04 9.9e-06 2.2e-05 6.3e-05
16 Liver mRNA stability ENSRNOG00000022822 0.03 0.02 5.3e-03 0.01 0.01 0.01 0.01 1.1e-02 1.2e-02 5.1e-02 1.8e-02
17 NAcc gene expression ENSRNOG00000022822 0.25 0.09 0.0e+00 0.25 0.14 0.26 0 1.3e-18 2.4e-10 2.4e-19 1.9e-01
18 NAcc mRNA stability ENSRNOG00000022822 0.1 0.06 2.8e-03 0.03 0 0.01 0 3.5e-03 2.7e-01 2.5e-02 1.8e-01
19 OFC gene expression ENSRNOG00000022822 0.34 0.15 2.9e-04 0.16 0.13 0.11 0.14 1.4e-04 5.8e-04 1.7e-03 2.9e-04
20 PL gene expression ENSRNOG00000022822 0.25 0.1 1.1e-16 0.22 0.18 0.17 0.18 1.1e-16 1.3e-13 3.0e-13 1.1e-13
21 PL isoform ratio ENSRNOT00000040147 0.06 0.04 1.8e-04 0.06 0.04 0.04 0.04 3.5e-05 7.2e-04 2.6e-04 3.1e-04
22 PL isoform ratio ENSRNOT00000119682 0.06 0.04 1.4e-04 0.06 0.04 0.05 0.05 2.9e-05 5.6e-04 1.5e-04 2.1e-04
23 PL mRNA stability ENSRNOG00000022822 0.28 0.12 3.7e-15 0.2 0.09 0.12 0.03 1.6e-15 1.9e-07 9.9e-10 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
BMI with tail1.65.210.8-3.31.9-2.12.5-2.42.1-1.91.71.42.2-2.5-3.1-1.9-1.9-3.11.0-2.32.2-2.0-2.22.8-2.81.9
BMI without tail1.94.07.4-2.61.2-1.92.1-2.12.0-1.91.91.41.9-2.1-2.7-1.2-1.2-2.41.1-2.11.8-1.9-1.92.6-2.61.9
Body weight3.514.831.7-4.72.2-3.83.9-3.93.9-3.73.42.44.1-4.5-5.6-2.2-2.2-4.31.1-4.24.0-3.9-4.04.8-4.83.8
Epididymis fat weight0.81.911.4-2.82.2-0.71.0-1.00.10.1-0.2-0.20.4-0.8-1.4-2.5-2.2-3.4-0.1-0.50.6-0.2-0.31.0-1.00.1
Glucose0.71.13.1-0.2-0.3-1.81.1-1.11.0-0.90.71.61.2-1.3-0.50.70.30.01.8-1.11.6-1.0-1.20.5-0.51.0
Heart weight0.10.10.4-0.40.6-0.40.3-0.30.1-0.20.3-0.20.3-0.1-0.2-0.6-0.6-0.2-0.1-0.00.10.0-0.20.2-0.2-0.0
Left kidney weight0.61.66.9-1.92.40.70.4-0.4-0.81.2-1.3-1.3-0.70.60.1-2.6-2.4-1.7-0.80.9-0.91.00.80.1-0.1-1.0
Right kidney weight0.82.39.3-1.92.90.80.6-0.6-1.31.6-1.7-1.4-1.00.80.7-3.0-2.9-1.6-0.21.3-1.11.41.0-0.30.3-1.4
Tail length1.44.38.8-1.70.2-2.21.9-1.92.4-2.32.31.72.4-2.3-3.0-0.1-0.2-1.40.9-2.52.2-2.5-2.32.6-2.62.5
Length with tail2.49.022.5-3.00.9-3.12.7-2.73.3-3.13.01.93.3-3.6-4.7-1.0-0.9-2.80.3-3.53.3-3.4-3.23.6-3.63.4
Length without tail2.14.610.3-2.11.0-2.22.1-2.12.3-2.22.01.52.5-2.7-3.2-0.9-1.0-1.70.5-2.42.5-2.3-2.42.4-2.42.3
Liver weight, left0.50.82.9-1.71.4-0.31.2-1.20.4-0.30.30.50.6-0.6-0.7-1.4-1.4-1.10.5-0.50.5-0.5-0.61.0-1.00.5
Liver weight, right0.61.03.3-0.80.1-1.20.8-0.81.1-1.01.00.31.2-1.3-1.8-0.2-0.1-0.5-0.3-1.11.3-1.1-1.21.1-1.11.1
Parametrial fat weight2.85.513.0-3.51.9-1.52.1-2.12.1-2.22.21.01.9-2.3-3.6-2.0-1.9-3.40.2-2.31.9-2.2-2.03.1-3.12.2
Retroperitoneal fat weight0.72.218.4-2.92.1-0.0-0.00.0-0.00.2-0.3-0.90.1-0.3-1.6-2.5-2.1-4.3-1.7-0.4-0.00.0-0.10.7-0.70.0
Intraocular pressure0.20.32.6-1.10.70.00.0-0.0-0.20.4-0.50.2-0.50.10.0-0.5-0.7-1.60.40.0-0.30.30.5-0.20.2-0.2
Extensor digitorum longus weight0.73.07.2-2.72.0-1.31.8-1.81.3-1.41.40.11.3-1.7-2.7-2.1-2.0-2.3-0.3-1.31.2-1.3-1.22.3-2.31.3
Soleus weight0.30.83.9-1.60.9-0.60.4-0.40.6-0.70.7-0.00.7-0.8-1.5-1.0-0.9-2.0-0.8-0.70.6-0.6-0.71.0-1.00.6
Tibialis anterior weight0.30.93.4-1.01.10.4-0.60.6-0.70.7-0.8-1.6-0.70.4-0.5-1.4-1.1-1.7-1.80.7-0.60.80.7-0.20.2-0.7
Tibia length4.011.116.4-1.1-0.5-4.13.3-3.34.0-4.03.83.53.9-4.0-3.70.90.50.22.4-4.03.9-4.0-3.93.7-3.74.0
Number of licking bursts0.30.32.1-0.50.4-0.50.9-0.90.3-0.30.20.80.3-0.5-0.1-0.3-0.40.11.4-0.30.4-0.3-0.30.5-0.50.3
Food consumed during 24 hour testing period0.10.10.40.1-0.1-0.2-0.40.40.0-0.0-0.1-0.40.0-0.1-0.40.10.1-0.5-0.6-0.0-0.00.0-0.0-0.30.3-0.0
Times rat made contact with spout0.50.61.9-1.11.30.50.1-0.1-0.70.7-0.8-0.4-0.70.50.5-1.4-1.3-1.20.30.6-0.60.70.7-0.30.3-0.7
Mean time between licks in bursts3.04.26.72.1-1.02.0-2.12.1-2.12.2-2.2-1.8-2.12.32.50.81.02.0-1.52.3-2.02.22.1-2.62.6-2.2
Mean num. licks in bursts0.40.51.3-0.10.30.8-0.80.8-0.70.7-0.7-1.0-0.70.80.5-0.4-0.3-0.6-1.10.7-0.80.80.7-0.70.7-0.8
Std. dev. time between licks in bursts0.70.82.10.9-0.10.7-0.40.4-1.01.2-1.3-0.5-1.00.81.4-0.00.11.20.31.1-0.71.01.0-1.21.2-1.0
Water consumed over 24 hours0.20.31.3-0.60.70.3-0.40.4-0.50.5-0.7-0.5-0.50.30.1-0.7-0.7-1.1-0.20.4-0.20.50.5-0.40.4-0.5
Indifference point 0 sec1.62.63.8-0.5-0.5-1.91.7-1.71.8-2.01.81.81.8-1.9-1.80.50.50.21.5-1.91.7-1.9-1.81.7-1.71.9
Indifference point AUC4.65.410.6-1.40.3-2.42.7-2.72.6-2.72.91.92.5-2.8-2.9-0.2-0.3-0.11.4-2.52.6-2.6-2.43.3-3.32.5
Indifference point function ln k0.81.12.1-0.00.41.3-1.11.1-1.21.3-1.5-0.5-1.11.31.4-0.2-0.4-0.9-0.01.0-1.21.21.1-1.41.4-1.2
Indifference point function log k0.81.12.1-0.00.41.3-1.11.1-1.21.3-1.5-0.5-1.11.31.4-0.2-0.4-0.9-0.01.0-1.21.21.1-1.41.4-1.2
Delay discounting total patch changes 0 sec1.52.53.9-0.4-0.6-1.81.5-1.51.8-2.01.81.81.7-1.8-1.80.70.60.21.3-1.91.7-2.0-1.81.7-1.72.0
Delay discounting total patch changes 12 sec2.12.84.80.2-1.1-2.21.4-1.42.1-2.02.11.42.0-2.0-1.91.01.11.00.5-1.82.0-1.9-1.91.8-1.81.9
Delay discounting total patch changes 18 sec0.40.51.1-0.2-0.1-0.80.9-0.90.6-0.70.80.50.5-0.8-0.9-0.10.10.40.7-0.60.7-0.8-0.61.1-1.10.7
Delay discounting total patch changes 24 sec1.01.33.4-0.8-0.1-1.40.8-0.81.3-1.41.40.61.2-1.2-1.8-0.20.1-0.9-0.0-1.21.2-1.2-1.21.7-1.71.2
Delay discounting total patch changes 6 sec3.75.68.9-0.9-0.5-2.72.2-2.32.7-2.93.02.12.7-2.8-3.00.50.5-0.11.4-2.72.7-2.8-2.73.0-3.02.7
Delay discounting time to switch 0 sec2.84.36.61.8-0.81.9-2.62.6-2.22.2-2.2-2.4-2.12.32.10.40.80.8-2.52.2-2.12.12.1-2.52.5-2.2
Delay discounting water rate 0 sec0.50.81.4-0.80.2-0.70.8-0.81.1-1.21.21.01.0-0.9-1.2-0.0-0.2-0.70.7-1.10.8-0.9-1.01.0-1.01.0
Delay discounting water rate 12 sec0.40.61.7-0.3-0.2-0.60.6-0.60.9-1.01.01.30.8-0.8-0.60.50.2-0.21.2-1.00.8-0.9-0.90.7-0.70.9
Delay discounting water rate 18 sec0.60.85.5-1.61.50.5-0.10.1-0.50.5-0.6-0.3-0.70.40.2-1.4-1.5-2.40.20.4-0.60.60.6-0.20.2-0.6
Delay discounting water rate 24 sec0.40.53.5-1.41.20.3-0.00.0-0.30.3-0.5-0.2-0.30.3-0.0-1.2-1.2-1.90.10.3-0.30.60.3-0.20.2-0.5
Delay discounting water rate 6 sec0.10.21.3-0.40.30.3-0.50.5-0.20.2-0.1-0.4-0.20.3-0.1-0.4-0.3-1.1-0.50.2-0.30.40.2-0.20.2-0.4
Locomotor activity0.30.41.21.0-1.10.3-1.11.1-0.20.3-0.3-0.4-0.20.60.50.91.10.4-0.90.3-0.20.30.2-0.60.6-0.3
Locomotor testing distance0.30.61.80.8-0.90.7-1.31.3-0.50.6-0.7-0.6-0.40.80.50.70.9-0.1-0.90.4-0.50.60.4-0.90.9-0.5
Locomotor testing rearing0.81.23.11.8-1.50.5-1.31.3-0.70.7-0.8-0.1-0.61.01.41.61.51.30.20.7-0.60.80.6-1.41.4-0.7
Light reinforcement 10.71.32.3-0.2-0.5-1.11.1-1.11.4-1.30.91.31.5-1.2-1.40.60.50.41.0-1.41.3-1.5-1.51.1-1.11.4
Light reinforcement 20.40.51.9-1.31.40.11.0-1.00.3-0.30.1-0.10.3-0.3-0.7-1.4-1.4-0.6-0.1-0.20.2-0.3-0.30.9-0.90.2
Reaction time number correct3.34.79.0-3.02.2-1.82.8-2.81.9-1.81.71.71.9-2.2-2.3-1.8-2.2-2.22.0-2.01.9-1.7-2.02.7-2.71.8
Reaction time mean minus median0.30.41.50.8-0.9-0.3-0.30.30.5-0.60.8-0.30.3-0.3-0.80.80.91.0-1.2-0.30.3-0.7-0.30.1-0.10.7
Reaction time mean minus median AUC0.20.20.70.2-0.1-0.60.4-0.40.5-0.60.7-0.10.5-0.6-0.80.10.10.6-0.5-0.40.4-0.7-0.40.5-0.50.7
Reaction time num false alarms2.23.07.80.50.12.0-2.12.1-1.91.8-1.8-2.5-1.81.91.0-0.5-0.1-0.5-2.81.9-1.91.91.8-1.61.6-1.8
Reaction time num false alarms AUC2.13.07.80.10.52.0-2.02.0-1.91.8-1.8-2.5-1.91.91.0-0.9-0.5-0.9-2.81.9-1.91.91.9-1.41.4-1.8
Reaction time trials correct on left3.34.79.0-3.02.2-1.82.8-2.81.9-1.81.71.71.9-2.2-2.3-1.8-2.2-2.22.0-2.01.9-1.7-2.02.7-2.71.8
Reaction time trials on left3.24.58.4-2.92.1-1.72.7-2.71.9-1.81.71.71.9-2.1-2.3-1.8-2.1-2.12.0-1.91.9-1.7-1.92.6-2.61.8
Reaction time mean1.31.72.51.5-0.51.1-1.31.3-1.41.3-1.1-1.5-1.61.51.50.40.51.3-1.21.6-1.41.31.5-1.51.5-1.3
Reaction time mean AUC1.31.73.01.1-0.11.2-1.11.1-1.61.4-1.2-1.4-1.71.61.7-0.00.11.1-0.81.7-1.51.51.7-1.41.4-1.5
Median of all reaction times2.12.85.21.5-0.21.5-1.51.5-2.01.9-1.7-1.6-2.12.02.30.20.21.4-0.82.1-1.91.92.0-1.91.9-1.9
Reaction time omissions1.01.34.01.3-0.61.1-0.91.0-1.21.1-0.9-0.5-1.21.42.00.70.61.50.21.3-1.11.21.1-1.31.3-1.2
Reaction time false alarm rate4.46.313.41.4-0.52.8-3.33.3-2.72.6-2.5-3.2-2.72.81.9-0.10.5-0.0-3.72.7-2.82.62.7-2.62.6-2.6
Reaction time premature initiation rate0.30.51.91.3-1.40.4-0.90.9-0.10.1-0.2-0.3-0.10.40.21.11.40.9-0.50.1-0.1-0.00.0-0.70.7-0.1
Reaction time premature initiations0.30.40.8-0.1-0.3-0.50.5-0.50.9-0.70.60.60.8-0.7-0.80.30.3-0.00.6-0.90.8-0.9-0.90.6-0.60.8
Std. dev. reaction times0.50.61.81.2-0.80.6-1.01.0-0.60.4-0.1-1.0-0.80.70.50.70.81.1-1.30.7-0.70.40.8-0.70.7-0.4
Reaction time trials completed3.24.58.4-2.92.1-1.72.7-2.71.9-1.81.71.71.9-2.1-2.3-1.8-2.1-2.12.0-1.91.9-1.7-1.92.6-2.61.8
Reaction time trials AUC2.84.17.9-2.82.1-1.62.6-2.61.8-1.71.61.61.8-2.0-2.1-1.8-2.1-2.11.9-1.81.7-1.6-1.82.5-2.51.6
Social response proportion0.40.50.9-0.40.80.8-0.40.4-0.70.5-0.6-0.9-0.90.70.5-0.9-0.8-0.7-0.90.7-0.80.60.9-0.50.5-0.6
Social responses0.70.91.80.1-0.8-1.00.4-0.41.2-1.31.30.91.1-1.1-1.10.90.80.10.1-1.21.1-1.2-1.10.7-0.71.3
Social time0.30.41.00.5-0.9-0.70.2-0.20.7-0.60.40.90.6-0.5-0.31.00.90.70.4-0.70.4-0.7-0.60.1-0.10.8
Conditioned locomotion0.40.52.20.7-0.7-0.50.7-0.70.6-0.40.11.20.6-0.50.30.90.71.51.3-0.60.6-0.7-0.6-0.00.00.7
Cocaine response after cond. corrected0.70.82.21.0-1.2-0.80.2-0.20.9-1.00.91.00.9-0.7-0.41.51.21.30.3-0.80.8-0.9-0.90.2-0.20.9
Cocaine response after cond. not corrected1.71.93.00.7-1.2-1.60.9-0.91.6-1.71.71.51.6-1.5-1.21.41.21.30.6-1.51.6-1.6-1.61.0-1.01.6
Cocaine response before conditioning0.50.61.1-0.30.0-1.00.9-0.90.8-0.91.00.30.8-0.9-1.0-0.2-0.00.20.2-0.71.0-0.8-0.81.0-1.00.8
Saline control response0.50.73.41.7-1.7-0.4-0.50.50.2-0.30.30.20.2-0.10.21.71.71.8-0.3-0.10.3-0.3-0.3-0.30.30.3
Condit. Reinf. active minus inactive responses0.10.10.70.6-0.4-0.2-0.10.10.1-0.10.20.20.2-0.10.20.60.40.80.1-0.00.3-0.0-0.10.1-0.10.0
Condit. Reinf. active-inactive response ratio0.10.10.50.5-0.20.1-0.20.2-0.30.2-0.10.0-0.20.30.60.30.20.70.00.4-0.10.40.3-0.20.2-0.4
Condit. Reinf. active responses0.30.50.80.2-0.5-0.70.3-0.30.9-0.90.90.50.9-0.7-0.80.60.50.4-0.2-0.80.9-0.8-0.90.8-0.80.8
Condit. Reinf. inactive responses2.02.44.2-0.1-1.0-1.70.9-0.92.0-2.02.01.31.9-1.8-2.11.11.00.10.3-2.01.8-2.0-2.01.6-1.62.0
Condit. Reinf. lever presses1.52.03.5-1.00.3-1.61.4-1.41.6-1.51.41.21.6-1.6-1.9-0.2-0.3-0.80.7-1.71.8-1.6-1.61.9-1.91.6
Condit. Reinf. lever reinforcers received0.50.71.20.4-0.7-0.90.4-0.41.0-1.00.90.71.0-0.8-0.80.90.70.70.2-0.91.1-1.0-1.00.8-0.81.0
Pavlov. Cond. lever latency0.40.61.2-0.41.00.80.2-0.2-0.90.8-0.8-0.6-0.80.70.9-1.1-1.0-0.10.10.9-1.00.90.8-0.50.5-0.9
Pavlov. Cond. magazine entry latency4.45.18.1-0.2-1.0-2.61.9-1.92.7-2.82.82.52.6-2.6-2.41.41.00.71.6-2.62.7-2.7-2.72.4-2.42.7
Pavlov. Cond. change in total contacts0.71.01.60.2-0.9-1.10.1-0.11.2-1.31.30.91.2-1.1-1.21.00.9-0.2-0.0-1.21.2-1.2-1.21.0-1.01.2
Pavlov. Cond. index score1.21.52.50.4-1.1-1.40.4-0.41.5-1.61.51.21.5-1.3-1.41.31.10.30.4-1.51.6-1.5-1.51.1-1.11.5
Pavlov. Cond. latency score1.21.52.40.2-0.9-1.40.6-0.61.5-1.51.51.31.4-1.3-1.31.10.90.30.6-1.51.5-1.5-1.51.2-1.21.5
Pavlov. Cond. lever contacts0.50.71.20.4-0.9-0.9-0.10.11.0-1.01.00.70.9-0.8-1.01.00.90.0-0.0-1.01.1-1.0-1.00.7-0.71.0
Pavlov. Cond. magazine entry number1.21.53.3-1.01.61.3-0.40.4-1.31.5-1.5-1.3-1.31.21.0-1.8-1.6-1.2-0.61.3-1.41.31.3-0.80.8-1.3
Pavlov. Cond. intertrial magazine entries1.41.83.0-0.20.81.3-1.11.1-1.61.7-1.7-1.4-1.61.51.5-1.0-0.8-0.9-0.81.6-1.51.71.6-1.31.3-1.7
Pavlov. Cond. lever-magazine prob. diff.1.31.72.80.5-1.2-1.50.4-0.41.6-1.61.61.31.5-1.4-1.51.41.20.50.4-1.61.7-1.6-1.51.2-1.21.6
Pavlov. Cond. response bias1.31.83.20.8-1.6-1.50.1-0.11.6-1.71.71.21.5-1.3-1.51.81.60.60.0-1.61.7-1.6-1.61.0-1.01.6
Conditioned reinforcement - actives0.50.52.8-1.11.00.7-0.20.2-0.30.0-0.1-0.7-0.30.3-0.4-1.1-1.0-1.7-0.90.2-0.30.30.30.5-0.5-0.3
Conditioned reinforcement - inactives1.11.34.2-1.41.91.3-0.10.1-1.00.8-0.8-1.3-1.00.80.1-2.1-1.9-1.8-0.41.0-1.01.11.00.2-0.2-1.1
Conditioned locomotion0.80.93.0-1.10.1-0.80.5-0.51.2-1.11.00.50.9-1.1-1.7-0.2-0.1-1.3-0.7-1.20.9-1.2-0.91.0-1.01.2
Intermittent access intake day 1-15 change1.71.73.70.80.21.9-1.31.3-1.21.4-1.5-1.9-1.31.61.0-0.4-0.20.4-1.71.5-1.51.21.5-1.21.2-1.2
Intermittent access intake escalation0.90.82.10.60.21.4-0.80.8-0.81.0-1.1-1.4-1.01.10.7-0.3-0.20.4-1.21.1-1.10.81.0-0.80.8-0.8
Intermittent access intake escalation 20.80.81.50.70.01.2-0.90.9-0.81.0-1.1-1.2-1.11.11.0-0.1-0.00.5-0.91.0-1.10.81.1-0.90.9-0.8
Intermitt. access day 1 inactive lever presses0.70.84.4-1.71.60.50.4-0.4-0.3-0.10.3-0.2-0.20.0-0.3-1.6-1.6-2.10.00.1-0.10.30.21.1-1.1-0.3
Intermitt. access day 15 inactive lever presses0.60.72.1-1.01.40.80.3-0.3-0.70.8-0.7-0.4-0.80.50.6-1.4-1.4-1.10.80.7-0.60.70.80.3-0.3-0.7
Intermitt. access escalation Index0.20.11.10.1-0.5-0.3-0.50.50.10.1-0.3-0.20.2-0.1-0.50.40.5-0.2-1.1-0.20.3-0.2-0.2-0.30.30.2
Intermittent access day 1 total infusions2.32.74.70.00.81.9-1.31.3-2.12.0-1.8-1.4-2.11.81.9-0.9-0.8-0.7-0.52.0-2.02.22.1-1.41.4-2.2
Intermittent access day 15 total infusions1.92.13.90.40.52.0-1.41.4-1.61.7-1.8-1.6-1.91.71.5-0.5-0.5-0.2-1.11.7-1.91.71.9-1.41.4-1.7
Intermittent access terminal intake (last 3 days)1.92.13.30.40.51.7-1.21.2-1.81.8-1.8-1.3-1.81.71.8-0.5-0.50.0-0.61.8-1.71.81.8-1.41.4-1.8
Intermittent access total infusions1.51.62.7-0.10.71.6-1.01.0-1.61.6-1.5-1.2-1.61.51.4-0.7-0.7-0.5-0.51.6-1.61.71.6-1.01.0-1.7
Intermittent access day 1 locomotion0.80.93.4-1.81.6-0.31.0-1.00.1-0.10.10.6-0.2-0.4-0.2-1.4-1.6-1.71.4-0.2-0.1-0.00.20.9-0.90.0
Intermittent access day 15 total locomotion0.50.62.1-1.11.40.70.6-0.6-0.40.5-0.4-0.2-0.80.20.3-1.3-1.4-0.80.80.5-0.70.40.80.4-0.4-0.4
Intermittent access total locomotion0.30.41.3-1.11.0-0.10.8-0.80.3-0.20.30.3-0.0-0.3-0.5-0.9-1.0-0.80.6-0.2-0.0-0.20.00.9-0.90.2
Intermittent access standard deviation2.62.87.10.50.62.7-1.81.7-1.71.6-1.4-2.4-2.31.91.2-0.8-0.6-0.4-2.01.9-2.31.72.3-1.21.2-1.7
Cocaine induced anxiety0.30.32.8-0.40.20.5-0.70.7-0.20.5-0.4-0.9-0.50.4-0.2-0.4-0.2-0.8-1.70.3-0.50.30.5-0.30.3-0.3
Post-drug Anxiety0.91.02.40.8-1.6-1.0-0.10.21.2-1.01.21.00.9-1.0-0.91.51.60.6-0.2-1.21.0-1.3-0.90.3-0.31.3
Baseline Anxiety1.81.94.01.4-1.7-1.60.7-0.71.0-1.31.21.81.5-1.2-0.32.01.71.91.8-1.31.6-1.3-1.50.3-0.31.3
Lifetime Intake1.21.42.3-0.61.11.4-0.70.7-1.41.4-1.2-1.1-1.41.31.1-1.1-1.1-1.1-0.41.4-1.41.51.4-0.60.6-1.5
Incentive Sensitization - Responses2.32.35.00.10.82.2-1.11.1-1.91.8-1.8-1.2-1.81.82.0-0.8-0.8-0.3-0.21.8-1.81.91.8-1.51.5-2.0
Incentive Sensitization - Breakpoint2.82.86.00.30.62.4-1.31.3-2.12.0-2.0-1.3-2.02.12.3-0.7-0.6-0.0-0.32.0-2.02.12.0-1.71.7-2.1
Progressive ratio test 1 active lever presses1.51.67.0-2.32.40.80.5-0.5-0.51.0-1.0-0.7-0.50.3-0.3-2.5-2.4-2.70.10.5-0.50.70.50.5-0.5-0.7
Progressive ratio test 1 breakpoint1.61.77.3-2.32.40.90.5-0.5-0.61.0-1.1-0.8-0.50.3-0.2-2.5-2.4-2.70.10.6-0.50.80.50.4-0.4-0.8
Progressive ratio test 1 inactive lever presses2.22.49.1-2.83.00.81.0-1.0-0.90.9-0.9-0.5-0.60.30.1-3.0-3.0-2.91.00.7-0.51.00.60.8-0.8-1.0
Progressive ratio test 2 active lever presses1.41.53.1-1.31.61.8-0.20.3-1.21.5-1.4-0.7-1.21.11.0-1.6-1.6-1.50.31.2-1.21.41.2-0.50.5-1.4
Progressive ratio test 2 breakpoint1.01.12.5-1.21.41.6-0.10.1-1.01.2-1.2-0.6-1.00.90.8-1.4-1.4-1.40.31.0-1.01.21.0-0.30.3-1.2
Progressive ratio test 2 inactive lever presses3.23.76.7-1.52.12.6-1.11.1-2.22.1-1.9-1.7-2.32.01.6-2.3-2.1-2.6-0.62.0-2.22.22.3-0.80.8-2.2
Total sessions with >9 infusions0.80.93.1-1.51.70.60.2-0.2-0.90.8-0.8-0.6-0.70.50.4-1.7-1.7-1.8-0.00.7-0.60.90.70.4-0.4-0.9
Short access day 1 total inactive lever presses0.30.41.3-1.01.1-0.30.7-0.7-0.1-0.10.40.10.0-0.2-0.2-1.0-1.1-0.80.80.00.10.1-0.00.9-0.9-0.1
Short access day 10 total inactive lever presses1.01.12.5-1.60.9-0.81.2-1.20.8-1.00.91.00.9-1.1-1.2-0.8-0.9-1.40.8-1.10.9-1.0-0.91.2-1.21.0
Short access day 1 total infusions1.31.42.6-0.61.01.0-1.01.1-1.41.2-1.1-1.4-1.41.30.8-1.2-1.0-1.6-1.21.3-1.31.51.3-0.60.6-1.5
Short access day 10 total infusions2.02.23.6-0.81.51.9-1.01.0-1.71.7-1.5-1.8-1.71.51.1-1.7-1.5-1.5-1.11.8-1.71.91.7-0.70.7-1.9
Short access total infusions0.70.81.7-0.71.10.9-0.50.5-1.11.0-0.7-0.8-1.10.90.7-1.1-1.1-1.3-0.11.0-1.01.21.0-0.10.1-1.2
Short access day 1 locomotion1.01.13.4-1.40.9-0.90.6-0.60.6-1.01.1-0.10.6-1.0-1.7-1.0-0.9-1.6-0.7-0.70.7-0.6-0.61.8-1.80.6
Short access day 10 total locomotion0.20.30.9-0.80.7-0.30.3-0.30.3-0.40.5-0.2-0.1-0.3-0.6-0.7-0.7-0.9-0.3-0.10.0-0.10.10.8-0.80.1
Short access total locomotion1.11.14.7-2.11.5-0.50.9-0.90.3-0.60.60.20.1-0.6-1.0-1.5-1.5-2.20.2-0.40.2-0.4-0.11.6-1.60.4
Compulsive drug intake2.62.65.21.1-2.1-1.50.6-0.61.8-2.01.82.11.6-1.4-1.02.32.11.41.0-1.91.7-2.0-1.70.6-0.62.0
One hour access (0.3 mA shock)0.60.71.30.30.11.1-0.90.9-0.90.9-0.7-0.9-1.01.00.8-0.2-0.1-0.1-0.90.9-1.00.91.0-0.90.9-0.9
One hour access (shock baseline)0.91.02.0-0.10.81.1-0.80.8-1.11.2-0.9-1.4-1.11.10.8-0.9-0.8-0.5-1.21.3-1.21.31.1-0.70.7-1.3
Number of responses in last shaping day0.30.41.7-1.31.1-0.50.6-0.60.10.3-0.50.10.0-0.2-0.2-1.1-1.1-1.10.1-0.00.10.1-0.10.3-0.3-0.1
Context. condit. distance diff. score1.01.22.00.7-0.11.0-1.41.4-1.31.3-1.3-1.3-1.31.21.30.00.1-0.1-1.21.3-0.91.31.3-1.21.2-1.3
Locomotion velocity, session 11.01.12.91.0-1.5-0.70.5-0.50.9-1.00.91.50.9-0.7-0.11.71.51.71.6-0.80.7-0.9-0.90.3-0.30.9
Locomotion distance, session 11.11.42.2-0.3-0.3-1.31.2-1.21.4-1.41.41.01.5-1.3-1.40.30.30.30.8-1.41.4-1.4-1.51.3-1.31.4
Locomotion velocity, session 20.40.51.0-0.70.1-0.60.8-0.80.8-0.80.70.70.9-0.7-1.0-0.1-0.1-0.40.7-0.80.6-0.8-0.90.9-0.90.8
Locomotion distance, session 20.10.10.3-0.0-0.10.3-0.40.4-0.20.2-0.3-0.5-0.10.3-0.2-0.10.1-0.3-0.60.2-0.30.10.1-0.20.2-0.1
Locomotion velocity, session 32.83.25.91.2-2.1-1.80.9-0.92.0-2.01.92.32.1-1.6-1.12.42.11.81.4-2.02.0-2.0-2.11.2-1.22.0
Locomotion distance, session 30.91.02.91.1-1.5-0.70.2-0.21.0-1.11.11.41.0-0.6-0.21.71.51.31.0-0.90.9-0.9-1.00.5-0.50.9
Stereotopy head waving bouts, day 30.91.12.50.8-0.31.1-1.31.3-1.01.0-1.1-1.4-1.01.20.70.10.30.3-1.61.1-1.11.01.0-1.21.2-1.0
Stereotopy head waving duration, day 30.10.10.2-0.20.30.3-0.30.3-0.30.3-0.3-0.4-0.30.30.1-0.3-0.3-0.5-0.30.3-0.20.30.3-0.30.3-0.3
Locomotion velocity, session 72.32.64.4-0.2-0.5-1.81.6-1.61.8-1.91.82.11.9-1.8-1.20.80.50.41.9-1.91.9-1.9-1.91.7-1.71.9
Locomotion distance, session 70.10.10.50.4-0.7-0.2-0.20.20.3-0.40.40.40.3-0.2-0.10.60.70.10.1-0.30.4-0.3-0.30.1-0.10.3
Stereotopy head waving bouts, day 70.30.31.20.9-1.0-0.3-0.10.10.3-0.30.30.60.4-0.2-0.01.11.01.10.3-0.30.2-0.4-0.4-0.10.10.4
Stereotopy head waving duration, day 70.30.30.70.0-0.2-0.60.7-0.70.6-0.60.60.90.6-0.6-0.40.30.20.60.8-0.60.4-0.7-0.60.6-0.60.7
Locomotion velocity, session 81.01.22.81.0-1.5-1.20.3-0.31.2-1.21.11.31.3-1.0-0.71.71.51.10.7-1.21.3-1.2-1.30.5-0.51.2
Locomotion distance, session 80.71.01.90.5-0.11.1-1.41.4-1.11.1-1.1-1.3-1.01.20.8-0.10.1-0.4-1.41.1-1.01.11.0-0.90.9-1.1
Degree of sensitization distance0.60.61.5-0.71.00.7-0.40.4-0.80.8-0.8-1.0-0.80.60.2-1.2-1.0-1.2-0.80.7-0.70.80.8-0.50.5-0.8
Degree of sensitization stereotypy1.31.42.50.5-1.1-1.10.9-0.91.3-1.41.31.61.4-1.2-0.91.31.11.21.2-1.31.0-1.4-1.40.9-0.91.4
Condit. Reinf. active minus inactive responses4.14.58.7-2.51.3-1.92.2-2.22.0-2.42.51.62.0-2.3-2.6-1.1-1.3-2.31.1-2.21.9-2.1-2.12.9-2.92.1
Condit. Reinf. active-inactive response ratio2.12.33.8-1.81.2-1.41.8-1.81.3-1.51.61.21.3-1.7-1.6-1.0-1.2-1.61.3-1.51.3-1.4-1.42.0-2.01.4
Condit. Reinf. active responses2.02.55.3-1.80.9-1.41.5-1.51.5-1.82.01.21.5-1.7-1.9-0.7-0.9-1.80.7-1.71.4-1.5-1.52.3-2.31.5
Condit. Reinf. inactive responses0.20.30.90.9-0.90.2-0.70.8-0.30.10.0-0.0-0.30.40.50.90.90.6-0.30.2-0.20.20.3-0.30.3-0.2
Incentive salience index mean2.22.65.5-2.11.3-1.21.7-1.71.4-1.71.81.01.4-1.6-1.9-1.2-1.3-1.90.7-1.61.2-1.5-1.52.3-2.31.5
Condit. Reinf. lever presses0.50.61.4-1.00.5-0.50.7-0.70.7-0.91.00.50.8-0.7-1.0-0.4-0.5-1.00.1-0.90.5-0.8-0.81.2-1.20.8
Time in familiar zone, hab. session 10.70.71.7-0.10.50.9-0.90.9-0.80.8-0.8-1.3-0.90.80.2-0.7-0.5-0.7-1.20.8-0.90.90.9-0.60.6-0.9
Time in novel zone, hab. session 10.90.91.60.2-0.9-1.10.5-0.51.1-1.21.31.01.1-1.0-1.01.00.90.50.2-1.01.1-1.1-1.10.7-0.71.1
Total zone transitions, hab. session 12.23.25.40.4-1.7-1.90.8-0.82.1-2.32.31.92.2-1.9-1.91.81.70.50.7-2.21.9-2.2-2.21.5-1.52.2
Total locomotion distance, hab. session 10.71.02.10.9-1.4-0.9-0.10.11.1-1.21.30.41.1-0.9-1.41.41.41.0-1.0-1.00.8-1.1-1.10.6-0.61.1
Locomotion velocity, hab. session 10.30.41.00.6-0.9-0.3-0.30.30.5-0.70.7-0.00.6-0.4-0.80.90.90.6-1.0-0.50.3-0.6-0.60.3-0.30.6
Time in familiar zone, hab. session 21.01.01.81.3-0.71.0-1.31.2-1.00.9-0.9-1.0-0.91.01.00.60.71.0-1.01.0-0.80.90.9-1.21.2-0.9
Time in novel zone, hab. session 20.90.92.0-1.40.9-0.91.2-1.20.9-0.80.80.90.8-1.0-1.0-0.8-0.9-1.21.0-0.90.7-0.8-0.81.1-1.10.8
Total zone transitions, hab. session 21.31.63.3-0.3-0.8-1.50.5-0.51.6-1.61.61.11.6-1.4-1.80.80.8-0.50.2-1.61.4-1.6-1.61.4-1.41.6
Total locomotion distance, hab. session 20.20.32.90.3-0.60.1-0.70.70.1-0.20.2-0.80.10.1-0.80.40.6-0.2-1.7-0.1-0.2-0.1-0.1-0.00.00.1
Locomotion velocity, hab. session 20.20.22.30.2-0.50.0-0.60.60.2-0.20.3-0.60.2-0.0-0.90.30.5-0.3-1.5-0.2-0.1-0.2-0.20.1-0.10.2
Novel to familiar place preference ratio0.30.40.70.4-0.00.7-0.50.5-0.70.7-0.7-0.6-0.80.70.8-0.10.00.4-0.10.8-0.80.70.8-0.60.6-0.7
Novelty place preference0.50.50.70.6-0.20.8-0.70.7-0.80.8-0.8-0.7-0.80.80.80.10.20.5-0.40.9-0.80.80.8-0.70.7-0.8
Time in novel zone, NPP test0.30.40.60.5-0.10.6-0.60.6-0.70.7-0.7-0.6-0.70.70.70.10.10.3-0.30.8-0.70.70.7-0.60.6-0.7
Total zone transitions, NPP test0.91.32.1-0.2-0.7-1.30.8-0.81.4-1.41.41.21.4-1.3-1.40.70.7-0.20.7-1.51.4-1.4-1.41.1-1.11.4
Total locomotion distance, NPP test0.50.62.20.5-0.01.0-0.90.9-0.80.8-0.8-1.2-0.80.90.3-0.10.00.2-1.50.9-1.00.80.8-0.80.8-0.8
Locomotion velocity, NPP test0.50.72.00.5-0.11.1-1.01.0-0.80.8-0.8-1.2-0.80.90.4-0.10.10.3-1.40.9-1.10.80.8-0.80.8-0.8
Pavlov. Cond. lever latency0.60.81.40.4-0.00.7-0.80.8-1.01.1-1.0-0.9-1.11.01.2-0.20.00.1-0.61.1-0.71.21.1-1.01.0-1.2
Pavlov. Cond. magazine entry latency1.01.33.41.5-1.31.1-1.81.8-0.90.7-0.7-0.8-0.81.20.91.31.30.7-1.40.7-1.10.80.8-1.31.3-0.8
Pavlov. Cond. change in total contacts0.10.10.60.3-0.40.4-0.50.5-0.20.1-0.0-0.4-0.10.3-0.10.20.40.1-0.80.2-0.40.10.1-0.20.2-0.1
Pavlov. Cond. index score0.20.30.90.8-0.90.5-0.90.9-0.20.1-0.1-0.2-0.10.40.10.90.90.5-0.90.1-0.50.10.1-0.60.6-0.1
Pavlov. Cond. latency score0.20.30.80.9-0.80.5-0.80.8-0.20.0-0.1-0.2-0.00.40.10.90.80.6-0.80.1-0.50.00.1-0.50.5-0.0
Pavlov. Cond. lever contacts0.20.30.80.4-0.7-0.30.0-0.00.5-0.60.60.50.7-0.4-0.60.90.70.50.1-0.60.3-0.7-0.60.3-0.30.7
Pavlov. Cond. magazine entry number0.20.30.8-0.70.9-0.50.9-0.90.2-0.10.00.20.2-0.4-0.2-0.9-0.9-0.30.7-0.10.5-0.1-0.20.5-0.50.1
Pavlov. Cond. intertrial magazine entries0.20.21.80.9-0.6-0.60.2-0.20.2-0.30.40.20.2-0.20.20.60.61.30.50.00.5-0.1-0.10.2-0.20.1
Pavlov. Cond. lever-magazine prob. diff.0.30.31.00.8-0.70.7-1.01.0-0.40.2-0.3-0.4-0.30.60.20.70.70.3-1.00.3-0.60.20.3-0.60.6-0.2
Pavlov. Cond. response bias0.20.20.80.7-0.80.4-0.80.8-0.1-0.10.1-0.1-0.00.30.00.90.80.2-0.5-0.0-0.4-0.00.1-0.30.30.0
Bone: apparent density0.10.10.40.2-0.20.6-0.40.4-0.30.3-0.4-0.1-0.20.40.30.30.20.00.10.2-0.30.20.2-0.50.5-0.2
Bone surface0.20.31.50.7-0.8-0.40.3-0.30.4-0.40.30.50.4-0.3-0.01.00.81.20.6-0.30.4-0.4-0.4-0.10.10.4
Bone volume0.30.51.70.8-1.1-0.40.2-0.20.6-0.50.40.80.6-0.4-0.21.31.11.10.7-0.60.6-0.6-0.6-0.10.10.6
Bone: connectivity density0.10.10.4-0.30.40.50.0-0.0-0.40.5-0.6-0.4-0.30.30.1-0.4-0.4-0.20.10.4-0.40.40.3-0.30.3-0.4
Bone: cortical apparent density0.60.71.7-0.60.61.0-0.90.9-0.90.9-0.9-1.0-0.90.90.4-0.9-0.6-1.3-1.10.8-0.81.00.9-0.60.6-1.0
Bone: cortical area0.71.01.90.9-1.2-1.2-0.00.01.2-1.11.10.31.2-1.1-1.41.31.20.6-0.8-1.11.3-1.1-1.20.5-0.51.1
Bone: cortical porosity0.30.30.8-0.20.50.6-0.10.1-0.60.6-0.6-0.0-0.60.60.9-0.4-0.5-0.20.70.5-0.70.60.6-0.40.4-0.6
Bone: cortical porosity0.10.10.60.3-0.10.4-0.10.1-0.30.3-0.20.3-0.20.40.70.20.10.40.70.2-0.30.20.3-0.30.3-0.2
Bone: cortical thickness0.40.75.80.6-0.60.5-1.41.4-0.30.5-0.5-1.3-0.30.5-0.40.30.6-0.6-2.40.3-0.30.40.3-0.80.8-0.4
Bone: cortical thickness0.20.21.00.8-1.0-0.5-0.30.30.2-0.20.30.40.2-0.20.21.01.00.70.2-0.20.4-0.1-0.2-0.20.20.1
Bone: cortical tissue density0.50.61.4-0.50.50.9-0.80.8-0.80.8-0.8-0.9-0.80.80.4-0.8-0.5-1.2-1.00.7-0.80.90.8-0.60.6-0.9
Bone: elastic displacement0.40.41.6-0.70.70.8-0.50.5-0.70.6-0.6-0.5-0.70.60.4-0.7-0.7-1.2-0.40.5-0.90.60.7-0.40.4-0.6
Bone: elastic work0.30.32.8-0.30.10.2-0.90.9-0.0-0.00.1-0.8-0.00.1-0.8-0.2-0.1-1.4-1.7-0.1-0.2-0.10.10.0-0.00.1
Bone: endosteal estimation2.65.68.60.9-1.5-2.92.3-2.32.7-2.72.72.62.7-2.7-1.81.91.52.62.3-2.42.8-2.6-2.72.0-2.02.6
Bone: endosteal perimeter1.02.13.90.1-0.3-2.01.5-1.61.7-1.71.71.31.7-1.8-1.50.60.31.10.9-1.51.8-1.7-1.71.6-1.61.7
Bone: final force0.40.71.70.0-0.3-1.30.7-0.70.9-1.01.00.31.0-1.2-1.30.30.30.4-0.1-0.91.2-1.0-1.00.9-0.91.0
Bone: final moment0.50.82.00.0-0.4-1.30.7-0.71.0-1.11.10.41.1-1.2-1.40.50.40.3-0.2-1.01.2-1.1-1.00.9-0.91.1
Bone: marrow area2.45.28.01.0-1.6-2.82.2-2.22.6-2.62.62.52.6-2.5-1.72.01.62.62.2-2.32.7-2.5-2.61.9-1.92.5
Bone: maximum diameter1.52.85.00.7-1.2-2.11.1-1.12.1-2.02.01.52.1-1.9-1.71.51.21.30.6-1.92.2-2.0-2.01.4-1.42.0
Bone: maximum force0.71.22.70.3-0.9-1.50.6-0.71.3-1.31.40.51.4-1.4-1.70.90.90.6-0.2-1.21.4-1.3-1.31.0-1.01.3
Bone: maximum moment0.81.43.10.2-0.9-1.50.6-0.61.4-1.51.50.61.4-1.4-1.80.90.90.5-0.3-1.31.4-1.4-1.41.0-1.01.4
Bone: minimum diameter3.05.69.51.2-2.2-3.01.6-1.62.8-2.82.72.12.8-2.7-2.42.42.22.10.9-2.63.1-2.8-2.81.7-1.72.8
Bone: periosteal estimation2.34.77.61.0-1.7-2.71.5-1.52.6-2.62.51.92.6-2.5-2.22.01.72.00.9-2.32.8-2.5-2.61.7-1.72.5
Bone: periosteal perimeter1.93.25.41.0-1.5-2.31.1-1.12.2-2.12.01.52.2-2.1-1.91.81.51.70.4-2.02.3-2.1-2.11.3-1.32.1
Bone: post-yield work2.63.65.60.5-1.5-2.21.4-1.42.3-2.32.42.02.2-2.1-1.81.61.51.31.2-2.22.3-2.2-2.31.7-1.72.2
Bone: stiffness0.10.10.4-0.10.1-0.40.4-0.40.2-0.20.2-0.30.3-0.3-0.6-0.3-0.10.1-0.3-0.10.4-0.2-0.30.3-0.30.2
Bone: tissue strength0.70.62.3-1.21.30.9-0.10.1-0.50.6-0.6-0.8-0.50.5-0.2-1.5-1.3-1.5-0.80.4-0.60.50.5-0.00.0-0.5
Bone: trabecular number0.71.12.50.10.51.6-0.70.7-1.21.3-1.5-0.9-1.11.31.1-0.4-0.5-0.1-0.11.2-1.31.21.2-1.11.1-1.2
Bone: trabecular spacing3.03.95.9-0.7-0.3-2.32.2-2.22.2-2.42.42.22.2-2.3-1.90.40.30.31.8-2.22.1-2.2-2.22.2-2.22.2
Bone: trabecular thickness0.10.10.60.4-0.5-0.2-0.30.30.1-0.20.10.40.3-0.10.00.80.50.20.1-0.30.5-0.1-0.2-0.10.10.1
Bone: trabecular tissue density0.10.10.80.9-0.7-0.0-0.40.4-0.0-0.00.1-0.1-0.10.10.20.70.70.7-0.20.1-0.10.10.1-0.20.2-0.1
Breakpoint value in progressive ratio session0.10.10.3-0.50.50.00.1-0.1-0.00.2-0.1-0.2-0.2-0.0-0.3-0.5-0.5-0.6-0.40.0-0.2-0.00.20.2-0.20.0
Distance traveled before self-admin0.20.31.10.9-1.0-0.2-0.60.6-0.00.1-0.10.3-0.00.20.30.91.00.50.1-0.1-0.1-0.1-0.0-0.70.70.1
Distance traveled after self-admin0.10.10.6-0.60.50.10.2-0.20.10.2-0.2-0.10.1-0.1-0.6-0.6-0.5-0.8-0.0-0.3-0.0-0.4-0.10.1-0.10.4
Delta time in closed arm before/after self-admin0.40.41.5-0.60.1-1.20.5-0.50.5-0.60.50.20.8-0.8-1.1-0.2-0.1-0.5-0.5-0.70.9-0.6-0.90.6-0.60.6
Delta time in open arm before/after self-admin1.31.22.0-1.10.4-0.81.2-1.21.2-1.31.21.31.0-1.2-1.1-0.1-0.4-0.91.1-1.31.0-1.3-1.01.4-1.41.3
Diff in mean of infusions in LGA sessions0.20.31.2-0.3-0.2-0.5-0.10.10.5-0.60.70.00.4-0.5-1.10.10.2-0.7-0.7-0.60.4-0.7-0.40.3-0.30.7
Extinction: sum of active levers before priming3.13.16.9-2.11.4-1.52.0-2.01.5-1.71.91.31.5-1.8-2.1-1.1-1.4-1.81.4-1.71.5-1.7-1.52.6-2.61.7
Active lever presses in extinction session 61.41.33.7-1.70.9-0.91.1-1.11.0-1.20.90.41.1-1.3-1.9-1.1-0.9-1.6-0.0-1.11.1-1.0-1.11.3-1.31.0
Delta distance traveled before/after self-admin1.21.32.7-1.61.2-0.71.3-1.31.0-0.91.00.41.0-1.2-1.6-1.1-1.2-1.10.2-1.01.0-1.2-0.91.5-1.51.2
Delta ambulatory time before/after self-admin1.31.44.4-2.11.8-0.31.4-1.40.6-0.50.60.10.6-0.9-1.4-1.6-1.8-1.70.2-0.70.7-0.7-0.61.5-1.50.7
Time in closed arm before self-admin0.20.20.70.8-0.30.8-0.30.2-0.10.3-0.3-0.1-0.40.40.90.40.30.80.30.4-0.50.30.4-0.50.5-0.3
Time in closed arm after self-admin0.30.31.00.10.10.4-0.60.6-0.50.7-0.7-0.8-0.50.50.3-0.4-0.1-0.3-1.00.5-0.40.50.5-0.50.5-0.5
Time in open arm before self-admin0.10.20.50.5-0.7-0.1-0.60.6-0.30.2-0.2-0.30.10.1-0.20.60.70.2-0.60.10.10.2-0.2-0.40.4-0.2
Time in open arm after self-admin0.70.81.9-0.70.1-0.70.8-0.80.9-1.01.00.71.0-1.1-1.40.0-0.1-0.60.4-1.10.9-1.1-1.01.2-1.21.1
Sum of active levers in priming session hrs 5-60.20.20.4-0.50.0-0.50.3-0.20.7-0.60.60.30.3-0.4-0.60.1-0.0-0.6-0.3-0.50.3-0.5-0.40.6-0.60.5
Time to tail flick, vehicle, before self-admin1.61.63.9-0.20.91.4-0.30.3-1.51.4-1.8-0.5-1.51.32.0-0.9-0.9-0.41.11.5-1.21.71.4-1.21.2-1.7
Time to tail flick, vehicle, after self-admin1.51.63.5-1.20.1-1.01.0-1.01.4-1.51.71.60.9-1.3-1.1-0.0-0.1-1.31.4-1.40.9-1.4-0.91.9-1.91.4
Time to tail flick, test, before self-admin0.30.31.60.6-0.5-0.40.4-0.40.3-0.40.20.90.6-0.40.40.90.51.31.2-0.20.5-0.1-0.7-0.10.10.1
Time to tail flick, test, after self-admin0.40.51.0-0.71.00.6-0.00.1-0.70.4-0.4-0.2-0.80.60.8-1.0-1.0-0.80.50.7-0.90.70.90.2-0.2-0.7
Delta time to tail flick, vehicle, before/after SA1.81.84.4-1.1-0.0-1.20.7-0.71.5-1.72.10.91.1-1.4-2.00.10.0-1.2-0.2-1.61.0-1.6-1.12.0-2.01.6
Delta time to tail flick, test, before/after SA0.10.10.4-0.40.3-0.1-0.10.1-0.0-0.00.2-0.1-0.30.1-0.2-0.4-0.3-0.6-0.40.0-0.2-0.10.40.6-0.60.1
Ambulatory time before self-admin0.20.20.80.7-0.9-0.3-0.50.50.00.1-0.10.30.10.10.20.80.90.30.1-0.1-0.0-0.1-0.1-0.50.50.1
Ambulatory time after self-admin0.30.31.4-1.00.8-0.20.5-0.50.3-0.10.30.10.4-0.4-0.9-0.8-0.8-1.20.2-0.50.2-0.5-0.40.6-0.60.5
Total heroin consumption0.70.83.3-1.11.10.9-0.50.5-0.80.8-0.7-1.0-1.00.70.1-1.3-1.1-1.8-0.70.7-0.90.71.0-0.10.1-0.7
Area under the delay curve0.30.30.60.2-0.10.8-0.70.7-0.60.5-0.4-0.6-0.70.70.6-0.00.1-0.2-0.70.6-0.70.70.6-0.10.1-0.7
Delay disc. indifference point, 0s delay0.60.72.11.4-1.20.5-1.01.0-0.50.5-0.5-0.4-0.50.60.81.21.21.2-0.60.6-0.50.50.4-0.80.8-0.5
Delay disc. indifference point, 16s delay0.20.20.80.7-0.90.2-0.70.7-0.0-0.20.2-0.0-0.10.1-0.00.90.90.3-0.4-0.0-0.10.10.0-0.10.1-0.1
Delay disc. indifference point, 2s delay0.50.61.3-0.1-0.1-0.70.9-0.90.9-0.80.91.00.8-0.7-0.30.30.10.41.0-0.70.8-0.6-0.81.1-1.10.6
Delay disc. indifference point, 24s delay0.10.10.2-0.30.30.3-0.10.1-0.2-0.00.1-0.3-0.20.2-0.2-0.3-0.3-0.4-0.30.2-0.30.20.20.3-0.3-0.2
Delay disc. indifference point, 4s delay0.10.11.0-0.40.20.1-0.20.20.0-0.10.1-0.4-0.0-0.1-0.3-0.4-0.2-0.7-1.0-0.00.00.1-0.10.4-0.4-0.1
Delay disc. indifference point, 8s delay1.31.42.10.7-0.31.4-1.51.5-1.31.2-1.2-1.1-1.41.41.40.10.30.2-1.11.3-1.31.41.4-1.11.1-1.4
Delay discount exponential model param0.30.30.6-0.1-0.1-0.80.7-0.70.6-0.50.40.70.7-0.7-0.60.20.10.20.7-0.70.7-0.8-0.70.1-0.10.8
Delay discount hyperbolic model param0.10.20.30.1-0.2-0.60.4-0.40.4-0.30.20.50.5-0.5-0.40.30.20.30.5-0.50.5-0.6-0.4-0.20.20.6
Fecal boli incidents, locomotor time 12.12.37.02.0-0.71.4-1.01.0-1.71.5-1.3-0.6-1.51.62.60.90.72.40.81.8-1.51.61.6-1.51.5-1.8
Change in fecal boli incidents, locomotor task1.81.83.0-0.60.81.6-1.31.3-1.41.5-1.5-1.5-1.51.40.9-1.1-0.8-1.4-1.71.3-1.51.41.5-1.21.2-1.3
Time >=10cm from walls, locomotor time 10.30.30.90.5-0.9-0.2-0.30.30.4-0.70.80.40.4-0.3-0.50.90.90.1-0.3-0.60.5-0.6-0.40.2-0.20.5
Bouts of movement, locomotor time 10.10.21.10.9-0.40.3-0.10.1-0.10.2-0.3-0.1-0.20.30.40.60.41.00.40.3-0.30.20.2-0.40.4-0.1
Total resting periods, locomotor time 10.20.21.20.9-0.50.3-0.20.2-0.10.1-0.1-0.1-0.20.30.30.70.51.10.30.3-0.30.10.2-0.30.3-0.1
Rest time, locomotor task time 11.21.36.71.9-1.9-0.60.1-0.00.3-0.50.41.30.5-0.30.52.11.92.61.5-0.40.4-0.5-0.6-0.60.60.5
Distance moved, locomotor task time 11.11.24.6-1.71.90.80.1-0.1-0.40.6-0.7-1.3-0.70.5-0.2-2.2-1.9-2.0-1.30.5-0.60.60.7-0.00.0-0.6
Vertical activity count, locomotor time 10.30.31.1-0.81.00.30.1-0.1-0.20.2-0.1-0.7-0.30.2-0.0-1.1-1.0-0.8-0.80.3-0.20.30.30.2-0.2-0.2
Time >=10cm from walls, locomotor time 21.92.07.11.7-2.5-1.0-0.00.01.1-1.21.01.61.4-1.0-0.32.72.52.00.7-1.21.4-1.2-1.4-0.00.01.1
Bouts of movement, locomotor time 20.30.31.2-0.60.4-0.31.0-1.00.4-0.40.40.90.6-0.6-0.2-0.3-0.40.11.1-0.50.5-0.5-0.50.5-0.50.5
Total resting periods, locomotor time 20.50.51.5-0.40.1-0.41.1-1.10.7-0.70.61.10.8-0.8-0.4-0.1-0.10.41.2-0.70.7-0.7-0.70.7-0.70.7
Rest time, locomotor task time 20.30.41.30.5-0.7-0.40.5-0.50.6-0.70.70.80.5-0.5-0.40.70.71.10.7-0.60.4-0.8-0.60.2-0.20.8
Distance moved, locomotor task time 20.20.20.4-0.20.1-0.30.3-0.30.6-0.50.50.10.4-0.4-0.7-0.1-0.1-0.2-0.3-0.50.4-0.5-0.40.6-0.60.6
Vertical activity count, locomotor time 20.10.10.60.6-0.20.0-0.10.1-0.20.3-0.3-0.1-0.30.30.70.20.20.80.10.4-0.20.40.3-0.30.3-0.2
Weight adjusted by age2.22.55.00.3-1.0-2.01.2-1.22.0-2.01.91.42.2-1.8-1.81.21.00.80.5-1.92.2-1.8-2.11.2-1.21.8
Seeking ratio, delayed vs. immediate footshock0.40.43.2-0.10.10.5-0.80.8-0.30.10.7-1.2-0.50.4-0.5-0.3-0.1-0.7-1.80.4-0.60.30.60.4-0.4-0.4
Locomotion in novel chamber2.02.44.60.70.11.5-1.71.7-1.42.0-2.1-2.0-1.51.71.3-0.5-0.1-0.1-2.11.7-1.41.71.4-2.12.1-1.7
Locomotion in novel chamber post-restriction0.60.72.2-0.91.21.0-0.20.2-0.30.8-1.1-1.3-0.60.4-0.3-1.5-1.2-1.0-1.40.6-0.50.60.5-0.50.5-0.5
Progressive ratio0.40.45.0-0.20.1-0.50.9-0.90.2-0.20.01.30.3-0.30.60.1-0.10.12.2-0.40.3-0.4-0.20.2-0.20.4
Food seeking constrained by brief footshock0.20.30.7-0.50.80.10.2-0.2-0.60.6-0.70.2-0.30.20.6-0.9-0.8-0.80.80.3-0.20.40.3-0.50.5-0.4
Seeking ratio, punishment vs. effort0.40.52.30.10.30.8-0.80.8-0.60.7-0.6-1.2-0.60.60.0-0.6-0.3-0.4-1.50.7-0.60.70.5-0.60.6-0.7
Run reversals in cocaine runway, females0.30.30.80.00.40.3-0.50.5-0.60.6-0.6-0.9-0.70.60.5-0.4-0.4-0.2-0.80.7-0.70.70.7-0.30.3-0.7
Run reversals in cocaine runway, males1.81.75.5-2.32.1-0.41.5-1.50.7-0.60.60.40.8-0.9-1.1-2.0-2.1-2.31.1-0.80.7-0.7-0.81.4-1.40.7
Latency to leave start box in cocaine runway0.70.73.81.1-1.5-0.3-0.80.80.5-0.40.5-0.40.4-0.2-0.81.31.51.1-1.9-0.30.4-0.5-0.4-0.30.30.6
Latency to leave start box in cocaine runway, F0.20.21.30.8-0.7-0.1-0.20.20.1-0.1-0.0-0.20.10.0-0.00.70.71.1-0.60.00.1-0.2-0.1-0.60.60.2
Latency to leave start box in cocaine runway, M0.70.74.90.7-1.4-0.1-1.11.10.3-0.30.6-0.60.3-0.2-0.91.11.40.3-2.2-0.20.3-0.3-0.30.1-0.10.3
Cd content in liver0.50.52.91.2-1.2-0.2-0.90.9-0.0-0.00.1-0.6-0.00.1-0.20.91.21.0-1.70.20.10.00.0-0.50.5-0.0
Co content in liver2.32.77.60.60.62.1-0.80.8-2.11.9-1.8-0.9-2.12.02.8-0.5-0.60.90.42.1-2.12.02.1-1.71.7-2.0
Cu content in liver0.10.20.70.3-0.20.4-0.70.7-0.40.3-0.3-0.6-0.40.5-0.00.00.2-0.0-0.80.3-0.60.30.4-0.40.4-0.2
Fe content in liver3.54.27.1-2.01.2-2.12.7-2.72.0-2.12.02.02.0-2.3-2.2-0.9-1.2-1.02.2-2.12.0-2.0-2.02.6-2.62.0
K content in liver0.30.30.5-0.10.70.60.2-0.2-0.60.5-0.6-0.4-0.60.50.7-0.7-0.70.30.40.6-0.70.40.6-0.00.0-0.4
Mg content in liver0.30.31.10.10.60.60.1-0.2-0.70.7-0.7-0.2-0.70.61.1-0.5-0.60.50.70.8-0.70.60.7-0.30.3-0.6
Mn content in liver0.60.71.7-0.20.71.2-0.40.4-1.01.0-0.9-0.4-1.11.01.3-0.7-0.7-0.40.51.0-1.21.01.1-0.50.5-1.0
Na content in liver4.14.49.8-0.80.1-2.22.8-2.82.3-2.12.02.72.3-2.3-1.40.3-0.10.83.1-2.22.3-2.3-2.32.2-2.22.3
Rb content in liver0.20.20.7-0.50.80.50.1-0.1-0.50.4-0.4-0.4-0.40.30.2-0.9-0.8-0.4-0.00.4-0.60.30.40.2-0.2-0.3
Se content in liver1.72.03.60.40.21.9-1.51.5-1.51.6-1.6-1.9-1.51.71.0-0.5-0.2-0.0-1.91.6-1.81.51.5-1.51.5-1.5
Sr content in liver3.23.05.0-0.00.72.2-1.71.7-2.02.0-1.8-1.9-2.02.11.7-0.9-0.7-1.1-1.41.9-2.12.02.0-1.71.7-2.0
Zn content in liver1.21.32.80.10.81.4-0.90.9-1.41.2-1.2-1.7-1.41.30.9-1.0-0.8-0.5-1.11.4-1.31.31.4-0.90.9-1.3