Hub : Genes

Pced1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000009199 0.15 0.09 3.1e-15 0.1 0.12 0.12 0.12 5.6e-11 3.9e-13 6.2e-13 2.0e-13
2 Adipose alternative TSS ENSRNOT00000118269 0.05 0.04 3.2e-06 0.03 0.04 0.04 0.03 3.2e-04 6.5e-05 6.4e-05 1.5e-04
3 Adipose alternative TSS ENSRNOT00000009199 0.14 0.08 2.6e-14 0.1 0.11 0.11 0.11 4.6e-11 4.0e-12 2.1e-12 2.7e-12
4 Adipose alternative TSS ENSRNOT00000118269 0.12 0.08 5.4e-10 0.06 0.07 0.07 0.07 6.5e-07 3.7e-08 5.9e-08 4.2e-08
5 Adipose gene expression ENSRNOG00000022807 0.1 0.1 3.2e-05 0.03 0.02 0.03 0.02 4.3e-04 1.0e-03 4.3e-04 8.9e-04
6 Adipose isoform ratio ENSRNOT00000009199 0.05 0.05 1.4e-04 0.02 0.02 0.02 0.02 4.5e-03 2.3e-03 2.4e-03 5.4e-03
7 Adipose intron excision ratio chr7:128505124:128526585 0.06 0.04 1.3e-07 0.05 0.05 0.05 0.05 1.6e-06 1.1e-06 2.1e-06 3.2e-06
8 BLA alternative TSS ENSRNOT00000009199 0.06 0.05 6.8e-04 0.07 0.02 0.04 0.02 1.9e-04 4.5e-02 5.8e-03 4.0e-02
9 BLA alternative TSS ENSRNOT00000098442 0.05 0.04 2.2e-03 0.04 0.03 0.04 0.03 1.9e-03 1.6e-02 4.4e-03 6.1e-03
10 Brain alternative TSS ENSRNOT00000009199 0.03 0.03 1.8e-03 0.01 0.01 0.01 0.01 2.3e-02 1.7e-02 6.6e-02 3.9e-02
11 Brain alternative TSS ENSRNOT00000009199 0.04 0.04 1.5e-03 0.01 0.01 0 0 6.3e-02 3.1e-02 1.0e-01 1.1e-01
12 Brain alternative TSS ENSRNOT00000118269 0.03 0.03 5.6e-04 0.02 0.02 0.02 0.02 1.2e-02 5.2e-03 5.9e-03 1.1e-02
13 LHb gene expression ENSRNOG00000022807 0.16 0.16 8.9e-03 0.08 0.07 0.09 0.09 6.1e-03 8.7e-03 4.3e-03 4.6e-03
14 Liver alternative TSS ENSRNOT00000009199 0.15 0.09 0.0e+00 0.14 0.15 0.16 0.14 8.6e-15 1.2e-16 6.6e-17 1.1e-15
15 Liver alternative TSS ENSRNOT00000098442 0.03 0.03 2.0e-03 0.02 0.01 0.02 0.01 2.5e-03 1.2e-02 5.2e-03 9.7e-03
16 Liver alternative TSS ENSRNOT00000118269 0.03 0.02 1.1e-03 0.01 0.02 0.01 0.01 1.5e-02 2.6e-03 1.6e-02 1.7e-02
17 Liver alternative TSS ENSRNOT00000009199 0.14 0.09 0.0e+00 0.14 0.15 0.14 0.14 9.6e-16 4.3e-16 9.1e-16 7.6e-16
18 Liver alternative TSS ENSRNOT00000118269 0.11 0.07 4.4e-14 0.11 0.11 0.11 0.11 6.2e-12 1.9e-12 2.3e-12 2.1e-12
19 Liver isoform ratio ENSRNOT00000009199 0.14 0.09 1.1e-16 0.13 0.14 0.15 0.14 3.1e-14 8.7e-15 4.4e-16 2.5e-15
20 Liver isoform ratio ENSRNOT00000037874 0.02 0.02 4.0e-03 0.01 0 -0 0 5.0e-02 1.1e-01 6.4e-01 1.4e-01
21 NAcc gene expression ENSRNOG00000022807 0.06 0.04 3.5e-05 0.07 0.05 0.04 0.06 1.0e-05 7.1e-05 3.0e-04 4.5e-05
22 PL isoform ratio ENSRNOT00000098442 0.04 0.03 5.2e-03 0.02 0.03 0.02 0.02 7.1e-03 4.2e-03 8.3e-03 5.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail2.78.716.62.2-2.32.4-2.41.23.0-3.24.1-2.22.72.8-2.9-3.53.9-2.6-3.23.8-3.90.2-2.8-3.0-3.8
BMI without tail0.40.84.5-1.21.2-1.00.9-2.0-0.50.20.41.2-0.7-0.50.50.20.80.70.30.2-0.22.10.50.2-0.1
Body weight4.217.932.63.2-3.33.4-3.92.34.4-4.85.7-2.84.14.2-4.3-4.94.8-3.8-4.85.4-5.5-0.4-3.8-4.4-5.3
Epididymis fat weight0.51.14.80.5-0.50.6-0.5-0.30.8-1.11.2-0.60.91.0-1.0-1.12.2-0.9-1.01.3-1.31.2-0.9-1.3-1.2
Glucose0.00.10.5-0.20.3-0.20.2-0.7-0.10.10.30.4-0.3-0.30.20.00.20.00.10.2-0.20.3-0.1-0.0-0.3
Heart weight0.20.31.0-0.60.6-0.50.7-1.0-0.50.30.01.0-0.6-0.50.50.30.30.30.3-0.00.01.00.20.5-0.1
Left kidney weight0.41.25.10.5-0.50.6-0.4-0.60.7-1.11.1-1.01.01.0-1.0-1.12.3-1.3-1.01.1-1.21.9-1.2-1.0-1.1
Right kidney weight1.64.69.31.8-1.71.9-1.91.02.2-2.43.0-1.21.92.0-2.1-2.62.1-2.3-2.32.8-2.8-0.0-2.3-2.0-2.8
Tail length0.31.14.7-1.41.4-1.31.0-1.7-0.90.7-0.22.2-1.0-0.90.90.8-0.40.90.7-0.50.41.11.00.50.5
Length with tail1.34.88.51.7-1.71.7-2.21.62.4-2.52.9-0.92.22.2-2.3-2.52.0-1.9-2.62.8-2.8-0.9-1.9-2.3-2.6
Length without tail7.015.318.73.8-3.93.8-4.03.74.1-4.24.3-3.64.04.0-4.1-4.33.4-3.8-4.24.3-4.3-2.0-3.7-3.7-4.2
Liver weight, left2.74.36.32.4-2.42.5-2.12.02.0-1.91.7-2.42.12.0-2.0-2.11.7-2.4-1.91.8-1.8-1.3-2.4-2.4-1.9
Liver weight, right1.93.25.91.7-1.71.8-1.91.71.9-1.91.8-2.41.91.9-1.9-1.91.2-1.6-1.91.8-1.8-0.1-1.7-1.9-1.6
Parametrial fat weight0.51.12.8-1.01.0-1.01.2-1.2-1.20.9-1.4-0.1-0.7-0.70.80.90.30.81.1-1.21.21.70.80.61.3
Retroperitoneal fat weight0.10.31.7-0.20.2-0.20.6-0.9-0.50.2-0.30.5-0.2-0.10.2-0.01.3-0.10.3-0.20.21.3-0.10.10.2
Intraocular pressure6.69.416.8-2.62.6-2.73.0-2.3-3.33.4-4.11.9-2.9-2.93.13.4-2.82.63.5-3.83.81.32.73.23.7
Extensor digitorum longus weight4.919.626.84.1-4.14.2-4.33.44.6-4.85.2-2.94.44.5-4.6-4.94.6-4.5-4.85.1-5.1-1.8-4.5-4.7-5.0
Soleus weight0.92.63.81.6-1.51.6-1.51.31.6-1.61.8-0.81.51.6-1.6-1.71.6-1.8-1.71.8-1.8-0.9-1.8-2.0-1.9
Tibialis anterior weight2.07.19.82.5-2.62.6-2.72.32.8-2.83.1-1.62.62.6-2.7-2.92.5-2.6-2.93.0-3.0-1.6-2.6-2.7-3.0
Tibia length6.217.622.24.3-4.44.3-4.74.64.6-4.44.0-4.24.64.5-4.5-4.32.7-4.1-4.54.2-4.2-2.6-4.1-3.9-4.0
Number of licking bursts0.40.52.9-0.40.5-0.50.10.2-0.30.6-0.50.9-0.6-0.70.60.7-1.70.70.5-0.50.6-1.10.70.80.5
Food consumed during 24 hour testing period1.01.23.41.0-1.11.1-0.90.51.0-1.11.2-0.71.01.1-1.1-1.21.8-1.1-1.11.2-1.20.0-1.1-1.3-1.2
Times rat made contact with spout0.10.10.30.2-0.20.2-0.2-0.20.2-0.30.30.20.30.3-0.3-0.30.6-0.4-0.30.3-0.3-0.0-0.3-0.3-0.4
Mean time between licks in bursts0.71.02.4-1.01.1-1.01.1-1.3-1.11.1-0.91.5-1.2-1.21.11.0-0.80.91.1-0.90.90.40.80.70.8
Mean num. licks in bursts0.40.43.60.1-0.20.20.2-0.7-0.0-0.40.2-0.70.50.5-0.4-0.51.9-0.6-0.20.3-0.31.5-0.6-0.7-0.3
Std. dev. time between licks in bursts0.50.61.4-0.50.5-0.50.8-0.7-0.90.9-1.20.7-0.8-0.80.80.8-0.70.31.0-1.11.10.30.40.51.0
Water consumed over 24 hours0.20.20.50.5-0.50.5-0.20.20.3-0.20.40.50.10.1-0.2-0.50.7-0.5-0.20.4-0.4-0.7-0.5-0.6-0.6
Indifference point 0 sec0.71.23.1-0.90.9-1.00.5-0.1-0.90.9-1.60.3-0.7-0.70.81.3-1.41.10.9-1.41.4-0.01.31.81.6
Indifference point AUC0.00.00.4-0.20.2-0.1-0.0-0.3-0.1-0.0-0.2-0.40.10.1-0.00.2-0.00.20.0-0.20.20.60.10.00.3
Indifference point function ln k1.62.25.01.0-1.01.0-1.50.81.7-1.82.2-0.81.41.5-1.6-1.71.3-1.1-1.82.1-2.1-0.5-1.1-1.4-1.9
Indifference point function log k1.62.25.01.0-1.01.0-1.50.81.7-1.82.2-0.81.41.5-1.6-1.71.3-1.1-1.82.1-2.1-0.5-1.1-1.4-1.9
Delay discounting total patch changes 0 sec0.71.12.9-0.80.8-1.00.50.1-0.80.9-1.60.2-0.6-0.70.81.3-1.41.00.9-1.41.4-0.21.21.71.6
Delay discounting total patch changes 12 sec0.30.41.4-0.00.1-0.10.00.7-0.40.5-1.2-0.7-0.1-0.20.30.7-1.00.50.5-1.01.0-0.60.40.91.1
Delay discounting total patch changes 18 sec1.41.95.7-0.70.7-0.80.70.2-1.11.5-2.00.1-1.1-1.21.21.7-2.41.21.4-1.91.9-0.91.21.81.8
Delay discounting total patch changes 24 sec0.70.94.1-0.20.3-0.30.30.8-0.61.0-1.10.1-0.8-0.90.91.0-2.00.80.9-1.11.1-1.80.81.01.0
Delay discounting total patch changes 6 sec1.21.83.9-1.21.2-1.31.0-0.7-1.31.3-1.80.5-1.1-1.11.21.6-1.51.31.3-1.71.70.51.32.01.9
Delay discounting time to switch 0 sec2.33.55.4-1.51.4-1.52.0-1.1-2.12.2-2.31.7-2.1-2.12.11.9-1.61.72.2-2.32.30.21.62.02.0
Delay discounting water rate 0 sec4.26.88.22.5-2.42.4-2.82.22.8-2.92.8-2.42.82.9-2.9-2.62.4-2.7-2.92.8-2.8-1.2-2.4-2.7-2.6
Delay discounting water rate 12 sec2.74.15.61.9-1.91.9-2.12.12.2-2.12.4-1.72.02.0-2.1-2.11.5-1.7-2.22.4-2.4-1.6-1.6-2.1-2.3
Delay discounting water rate 18 sec0.50.61.30.5-0.60.5-0.70.60.8-0.81.1-0.20.70.8-0.8-0.90.8-0.6-0.91.1-1.1-0.5-0.5-0.8-1.0
Delay discounting water rate 24 sec4.25.88.22.4-2.42.4-2.62.02.6-2.62.1-2.92.82.8-2.8-2.31.8-2.6-2.62.3-2.4-0.8-2.6-2.2-2.1
Delay discounting water rate 6 sec4.36.37.82.4-2.32.3-2.82.42.8-2.82.5-2.22.82.8-2.8-2.51.9-2.5-2.82.7-2.7-1.5-2.3-2.2-2.6
Locomotor activity0.71.11.8-0.90.9-0.91.0-1.0-1.11.2-1.21.2-1.1-1.11.11.1-1.10.81.2-1.21.20.60.81.31.1
Locomotor testing distance1.93.15.1-1.51.5-1.51.5-1.2-1.71.9-2.21.4-1.7-1.71.82.0-2.31.61.9-2.12.10.81.72.22.2
Locomotor testing rearing1.72.66.1-1.31.3-1.31.2-0.7-1.51.6-2.10.8-1.4-1.51.51.8-2.51.51.6-2.02.00.61.52.22.1
Light reinforcement 12.13.95.4-1.71.7-1.81.8-1.0-2.02.2-2.31.8-2.0-2.12.12.2-2.32.02.1-2.22.3-0.02.12.32.1
Light reinforcement 21.92.55.1-1.71.7-1.71.7-1.6-1.61.7-1.12.3-2.0-1.91.81.4-1.41.61.6-1.21.20.41.51.51.0
Reaction time number correct0.60.82.50.9-0.90.8-1.11.21.0-0.80.7-0.40.90.9-0.9-0.70.3-0.7-0.90.9-0.9-1.6-0.7-0.9-0.8
Reaction time mean minus median8.110.515.0-3.03.0-2.93.9-3.3-3.83.6-3.43.0-3.6-3.63.63.1-1.62.73.8-3.63.62.32.73.03.2
Reaction time mean minus median AUC5.57.010.2-2.32.2-2.23.2-2.5-3.23.1-2.92.6-3.0-3.03.02.5-1.42.03.2-3.13.11.52.02.52.6
Reaction time num false alarms2.12.84.4-2.12.0-2.11.6-2.1-1.61.3-1.61.7-1.3-1.31.41.8-0.92.01.4-1.51.51.92.01.61.8
Reaction time num false alarms AUC3.14.46.6-2.42.4-2.42.1-2.6-2.11.7-2.12.1-1.7-1.61.82.2-0.92.21.8-2.02.02.42.22.02.3
Reaction time trials correct on left0.60.82.50.9-0.90.8-1.11.21.0-0.80.7-0.40.90.9-0.9-0.70.3-0.7-0.90.9-0.9-1.6-0.7-0.9-0.8
Reaction time trials on left0.40.62.30.8-0.80.7-0.91.10.9-0.70.6-0.30.80.7-0.8-0.50.2-0.6-0.80.7-0.7-1.5-0.5-0.8-0.7
Reaction time mean0.50.61.4-0.20.2-0.21.2-0.7-1.21.0-1.10.6-0.9-0.91.00.50.20.01.2-1.11.10.60.00.10.7
Reaction time mean AUC0.20.30.70.1-0.00.10.8-0.4-0.80.7-0.80.3-0.6-0.60.60.20.4-0.30.8-0.80.80.6-0.3-0.20.5
Median of all reaction times0.20.20.90.8-0.70.70.10.2-0.10.0-0.1-0.30.10.1-0.1-0.40.7-0.80.1-0.10.1-0.0-0.9-1.0-0.2
Reaction time omissions6.08.113.7-2.32.3-2.33.2-2.4-3.43.2-3.71.8-2.9-2.93.13.0-1.72.23.4-3.63.61.82.22.83.3
Reaction time false alarm rate2.53.56.2-2.12.1-2.11.9-2.4-1.91.5-1.81.8-1.5-1.51.61.8-0.71.91.7-1.81.82.51.91.82.0
Reaction time premature initiation rate1.92.55.2-1.41.3-1.41.5-0.8-1.71.8-2.31.1-1.4-1.51.61.8-1.31.31.8-2.12.10.31.61.42.0
Reaction time premature initiations1.01.43.4-0.90.8-0.91.0-0.2-1.21.4-1.81.0-1.0-1.11.11.4-1.10.91.3-1.61.6-0.61.21.01.5
Std. dev. reaction times5.57.511.3-2.22.3-2.23.4-2.7-3.33.2-3.02.6-3.1-3.13.12.6-1.32.03.4-3.23.21.82.12.32.7
Reaction time trials completed0.40.62.30.8-0.80.7-0.91.10.9-0.70.6-0.30.80.7-0.8-0.50.2-0.6-0.80.7-0.7-1.5-0.5-0.8-0.7
Reaction time trials AUC0.81.12.61.0-1.00.9-1.31.31.2-1.00.9-0.61.11.1-1.1-0.80.5-0.8-1.11.1-1.1-1.6-0.8-1.1-1.0
Social response proportion0.90.93.3-1.21.1-1.20.9-0.7-0.90.8-0.70.5-0.9-0.90.90.8-0.90.90.9-0.90.90.80.91.81.0
Social responses7.69.915.9-3.33.2-3.33.2-2.6-3.33.2-3.32.4-3.1-3.13.23.2-2.73.03.3-3.43.41.93.24.03.4
Social time1.41.83.1-1.21.2-1.31.7-1.2-1.61.6-0.91.4-1.8-1.81.71.1-0.81.11.6-1.31.30.61.21.41.0
Conditioned locomotion0.20.30.5-0.70.7-0.70.6-0.6-0.50.5-0.10.7-0.7-0.70.60.4-0.40.60.5-0.20.20.20.70.60.1
Cocaine response after cond. corrected0.40.42.0-0.50.5-0.40.9-1.4-0.50.20.31.3-0.5-0.40.4-0.11.4-0.00.30.1-0.21.0-0.1-0.3-0.3
Cocaine response after cond. not corrected1.41.64.2-1.31.3-1.31.7-1.8-1.51.2-0.82.1-1.5-1.41.40.90.11.01.3-1.01.01.01.00.80.8
Cocaine response before conditioning4.35.310.4-1.91.8-1.91.8-0.7-2.22.5-3.01.3-2.2-2.32.32.7-3.22.42.4-2.82.8-0.12.52.62.8
Saline control response0.10.10.2-0.20.1-0.20.4-0.2-0.40.3-0.40.1-0.3-0.30.30.20.10.10.4-0.40.40.10.20.20.3
Condit. Reinf. active minus inactive responses0.10.10.2-0.30.2-0.30.20.3-0.10.2-0.00.2-0.3-0.30.20.1-0.30.50.1-0.10.1-0.30.50.40.1
Condit. Reinf. active-inactive response ratio0.50.61.5-1.11.0-1.10.6-0.5-0.60.4-0.3-0.2-0.6-0.50.60.6-0.71.20.4-0.40.41.11.21.00.6
Condit. Reinf. active responses0.30.40.9-0.50.4-0.50.50.1-0.50.7-0.51.0-0.7-0.70.70.6-0.80.80.6-0.60.6-0.80.80.70.4
Condit. Reinf. inactive responses1.01.23.5-0.70.7-0.71.0-0.3-1.01.3-1.11.9-1.2-1.31.21.1-1.31.01.2-1.11.2-1.31.01.00.9
Condit. Reinf. lever presses0.10.11.00.3-0.40.3-0.41.00.3-0.2-0.1-0.40.40.3-0.3-0.20.2-0.1-0.2-0.00.0-0.7-0.0-0.20.1
Condit. Reinf. lever reinforcers received0.50.61.0-0.70.6-0.70.7-0.0-0.70.9-0.80.9-0.9-0.90.90.8-0.91.00.8-0.80.8-0.61.00.90.7
Pavlov. Cond. lever latency0.10.10.6-0.40.5-0.40.3-0.8-0.10.20.30.4-0.4-0.30.30.1-0.40.10.10.1-0.10.30.10.2-0.2
Pavlov. Cond. magazine entry latency0.20.30.70.4-0.30.3-0.50.30.5-0.60.5-0.80.60.6-0.6-0.50.6-0.3-0.60.5-0.50.5-0.4-0.4-0.4
Pavlov. Cond. change in total contacts0.71.01.21.0-1.01.0-1.11.11.0-1.11.0-0.81.11.1-1.1-1.01.1-0.9-1.11.0-1.0-0.5-0.9-1.0-1.0
Pavlov. Cond. index score0.30.30.90.5-0.50.5-0.70.60.6-0.70.3-0.90.80.8-0.7-0.50.8-0.4-0.70.4-0.40.3-0.4-0.5-0.3
Pavlov. Cond. latency score0.40.41.10.6-0.60.5-0.70.60.6-0.80.4-1.00.90.9-0.8-0.60.9-0.5-0.80.5-0.50.3-0.5-0.6-0.3
Pavlov. Cond. lever contacts0.10.10.5-0.10.1-0.20.10.3-0.20.2-0.7-0.30.00.00.10.30.10.40.2-0.50.50.10.40.30.6
Pavlov. Cond. magazine entry number0.91.11.4-1.00.9-1.01.2-0.9-1.21.2-1.21.0-1.1-1.11.11.1-0.80.91.2-1.11.10.40.90.91.1
Pavlov. Cond. intertrial magazine entries1.41.83.2-1.21.2-1.21.4-1.1-1.51.5-1.80.9-1.3-1.31.41.5-1.31.21.5-1.61.60.41.21.31.6
Pavlov. Cond. lever-magazine prob. diff.0.40.61.10.7-0.70.7-0.90.80.8-0.90.5-1.01.01.0-0.9-0.70.9-0.6-0.90.7-0.70.1-0.6-0.7-0.5
Pavlov. Cond. response bias0.00.10.2-0.10.0-0.10.10.3-0.20.1-0.5-0.2-0.0-0.00.10.20.00.40.2-0.40.40.00.30.30.4
Conditioned reinforcement - actives0.90.91.7-0.90.9-0.91.2-1.0-1.21.0-1.30.1-0.9-0.90.90.9-0.00.51.1-1.21.21.30.50.81.1
Conditioned reinforcement - inactives0.60.71.9-0.80.8-0.71.0-0.9-1.00.8-1.2-0.5-0.7-0.70.70.80.20.50.9-1.01.01.40.60.81.0
Conditioned locomotion0.10.20.9-0.40.3-0.30.4-0.5-0.50.4-0.7-0.2-0.3-0.30.30.40.10.10.4-0.50.51.00.00.10.5
Intermittent access intake day 1-15 change1.31.32.3-1.31.3-1.31.3-1.0-1.21.2-1.11.3-1.3-1.21.21.1-0.41.31.2-1.01.00.31.51.00.8
Intermittent access intake escalation1.11.11.9-1.31.2-1.21.3-1.2-1.11.0-0.91.2-1.1-1.11.11.0-0.11.11.0-0.80.80.71.40.80.7
Intermittent access intake escalation 20.50.51.2-0.60.5-0.50.9-0.7-0.90.8-1.10.3-0.7-0.70.70.70.20.40.9-0.90.80.50.60.50.7
Intermitt. access day 1 inactive lever presses1.81.93.9-0.91.0-1.01.1-0.2-1.41.6-1.90.2-1.4-1.41.41.6-2.01.11.6-1.91.9-0.31.21.51.7
Intermitt. access day 15 inactive lever presses1.82.03.8-1.71.7-1.61.5-1.9-1.41.3-1.00.8-1.5-1.51.51.4-0.91.71.3-1.11.11.61.51.41.0
Intermitt. access escalation Index0.80.72.61.2-1.21.2-0.71.50.3-0.0-0.5-0.70.50.3-0.3-0.2-1.2-0.90.0-0.50.5-1.6-1.1-0.10.3
Intermittent access day 1 total infusions1.31.53.2-1.31.3-1.31.3-1.5-1.31.0-1.30.0-1.0-1.01.11.3-0.51.31.2-1.31.31.81.11.31.4
Intermittent access day 15 total infusions2.73.14.0-1.91.9-1.92.0-2.0-1.91.7-1.81.0-1.8-1.81.81.8-0.81.81.8-1.71.71.41.81.81.6
Intermittent access terminal intake (last 3 days)2.52.83.7-1.81.7-1.71.9-1.7-1.91.8-1.81.2-1.8-1.81.81.7-0.81.71.8-1.71.71.01.61.71.5
Intermittent access total infusions1.92.13.1-1.51.5-1.51.6-1.4-1.61.4-1.80.4-1.4-1.41.41.5-0.71.51.5-1.61.61.21.41.51.6
Intermittent access day 1 locomotion1.61.63.1-1.31.4-1.31.3-1.3-1.21.3-1.10.8-1.4-1.41.41.4-1.31.81.3-1.11.10.61.51.31.1
Intermittent access day 15 total locomotion1.11.21.8-1.11.2-1.21.1-0.8-1.11.1-1.10.7-1.2-1.21.21.1-1.01.31.1-1.01.00.61.21.21.0
Intermittent access total locomotion1.92.23.3-1.41.4-1.41.5-1.1-1.51.7-1.81.1-1.6-1.61.61.7-1.31.61.6-1.61.60.61.41.31.5
Intermittent access standard deviation1.31.42.5-1.51.5-1.41.5-1.6-1.31.1-0.90.4-1.3-1.21.21.00.11.21.2-0.90.91.41.31.00.8
Cocaine induced anxiety1.51.73.11.4-1.51.5-1.41.81.4-1.11.1-1.71.11.1-1.2-1.10.4-1.3-1.21.2-1.2-1.5-1.2-1.3-1.3
Post-drug Anxiety5.25.77.72.7-2.82.8-2.42.62.4-2.22.1-2.62.32.3-2.3-2.41.8-2.7-2.22.2-2.2-1.7-2.7-2.5-2.4
Baseline Anxiety1.51.62.51.4-1.31.3-1.20.91.2-1.41.1-1.01.51.5-1.4-1.41.5-1.5-1.31.0-1.1-0.2-1.6-1.2-0.9
Lifetime Intake1.41.62.4-1.41.4-1.41.3-1.3-1.41.2-1.60.1-1.1-1.11.21.4-0.61.31.3-1.41.41.41.21.31.4
Incentive Sensitization - Responses0.10.10.50.2-0.30.2-0.30.50.2-0.10.3-0.50.0-0.0-0.1-0.2-0.3-0.3-0.10.1-0.1-0.7-0.20.1-0.3
Incentive Sensitization - Breakpoint0.10.10.70.1-0.20.1-0.20.50.10.10.1-0.4-0.1-0.20.1-0.1-0.5-0.20.0-0.10.1-0.8-0.10.3-0.1
Progressive ratio test 1 active lever presses1.92.04.1-1.11.2-1.11.3-1.2-1.51.4-2.00.4-1.2-1.21.31.7-1.21.31.5-1.81.81.41.01.41.8
Progressive ratio test 1 breakpoint2.12.23.6-1.31.4-1.31.4-1.4-1.61.5-1.90.6-1.3-1.31.41.7-1.31.51.5-1.71.71.41.21.51.8
Progressive ratio test 1 inactive lever presses2.22.33.3-1.71.7-1.71.5-1.3-1.51.5-1.60.5-1.5-1.51.51.6-1.51.71.5-1.61.61.11.61.81.6
Progressive ratio test 2 active lever presses1.01.02.1-0.80.8-0.80.8-0.3-1.01.1-1.40.1-1.0-1.01.01.2-1.40.91.1-1.31.30.10.81.31.2
Progressive ratio test 2 breakpoint1.31.42.9-0.90.9-0.91.0-0.4-1.21.3-1.70.3-1.2-1.31.21.4-1.51.01.4-1.61.60.00.91.41.4
Progressive ratio test 2 inactive lever presses2.22.63.6-1.61.5-1.51.6-1.2-1.71.7-1.80.6-1.6-1.61.71.8-1.51.71.7-1.81.80.91.71.91.8
Total sessions with >9 infusions0.60.64.1-1.01.0-0.90.6-1.0-0.60.3-0.7-0.7-0.3-0.30.40.8-0.21.00.4-0.50.52.00.60.70.9
Short access day 1 total inactive lever presses0.30.41.9-0.60.5-0.50.5-0.6-0.60.3-1.0-0.7-0.1-0.10.20.70.30.40.5-0.70.71.40.40.40.9
Short access day 10 total inactive lever presses0.10.10.40.1-0.10.1-0.10.3-0.00.2-0.7-0.60.10.00.00.4-0.50.10.2-0.40.4-0.20.30.20.4
Short access day 1 total infusions0.10.11.1-0.40.4-0.30.1-0.6-0.0-0.20.2-0.30.10.1-0.1-0.00.40.4-0.10.1-0.21.0-0.00.20.0
Short access day 10 total infusions1.71.95.9-1.91.9-1.91.6-2.1-1.31.0-0.90.6-1.2-1.11.21.2-0.11.51.0-0.80.82.41.51.21.0
Short access total infusions0.30.31.5-0.70.7-0.70.5-0.7-0.40.2-0.5-0.5-0.2-0.20.30.50.10.50.3-0.30.31.20.40.50.5
Short access day 1 locomotion0.91.02.2-1.51.5-1.51.0-1.5-0.70.60.11.3-1.0-0.90.90.6-0.31.40.5-0.10.11.21.10.90.3
Short access day 10 total locomotion0.91.02.1-1.41.3-1.31.0-1.3-0.80.8-0.41.2-1.0-0.90.90.9-0.41.40.7-0.40.41.41.30.80.5
Short access total locomotion1.21.24.9-1.51.5-1.51.1-1.8-0.90.6-0.51.0-0.9-0.80.80.90.21.50.6-0.40.42.21.30.80.6
Compulsive drug intake0.50.50.90.8-0.80.7-0.80.70.8-0.70.8-0.60.60.6-0.7-0.80.2-0.6-0.70.7-0.7-0.9-0.6-0.6-0.7
One hour access (0.3 mA shock)0.20.20.3-0.40.3-0.30.6-0.4-0.50.4-0.5-0.6-0.5-0.50.50.30.10.00.5-0.50.50.50.20.50.3
One hour access (shock baseline)0.10.10.5-0.10.1-0.10.3-0.1-0.20.1-0.1-0.7-0.2-0.20.2-0.00.3-0.10.2-0.20.20.40.00.20.0
Number of responses in last shaping day0.50.62.5-1.21.2-1.20.5-1.3-0.1-0.10.60.6-0.4-0.30.20.10.40.9-0.10.5-0.61.60.70.4-0.4
Context. condit. distance diff. score0.50.61.80.8-0.70.7-0.71.00.7-0.70.7-1.30.70.7-0.7-0.80.6-0.7-0.70.7-0.7-0.2-0.6-0.8-0.7
Locomotion velocity, session 11.11.23.1-1.31.3-1.30.9-1.1-0.91.0-0.71.8-1.1-1.11.11.1-1.31.40.9-0.80.80.31.41.20.9
Locomotion distance, session 13.34.37.5-2.52.5-2.42.2-2.7-2.11.9-1.91.8-2.0-1.92.02.1-1.12.21.9-1.91.92.22.31.82.1
Locomotion velocity, session 20.30.31.0-0.70.7-0.70.7-0.9-0.60.4-0.51.0-0.5-0.40.50.40.50.50.5-0.50.40.60.40.50.5
Locomotion distance, session 22.53.67.6-2.22.3-2.22.1-2.8-2.01.7-1.71.5-1.7-1.61.71.8-0.51.81.8-1.71.72.41.81.61.8
Locomotion velocity, session 33.33.95.3-2.32.3-2.22.1-2.3-2.01.8-1.81.9-1.9-1.91.91.9-1.02.01.9-1.91.92.02.02.01.9
Locomotion distance, session 34.34.76.5-2.52.4-2.42.1-2.2-2.22.0-2.41.1-1.8-1.81.92.3-1.52.32.0-2.32.32.42.32.32.5
Stereotopy head waving bouts, day 30.60.71.20.9-0.80.9-0.60.30.8-0.71.0-0.40.70.7-0.7-0.80.8-1.0-0.70.9-0.9-0.7-1.0-1.1-1.1
Stereotopy head waving duration, day 30.10.10.40.4-0.30.4-0.1-0.20.2-0.20.50.30.10.1-0.2-0.30.4-0.4-0.20.5-0.5-0.5-0.5-0.6-0.6
Locomotion velocity, session 70.10.20.4-0.60.6-0.60.2-0.6-0.20.2-0.10.6-0.2-0.20.20.4-0.60.50.2-0.10.10.50.40.50.3
Locomotion distance, session 71.51.92.8-1.61.6-1.61.3-1.2-1.31.3-1.20.9-1.3-1.31.31.4-1.71.61.3-1.21.31.41.61.61.4
Stereotopy head waving bouts, day 71.21.31.71.2-1.11.2-1.30.91.3-1.21.1-1.21.21.2-1.2-1.00.9-1.2-1.21.2-1.2-1.0-1.2-1.2-1.1
Stereotopy head waving duration, day 72.53.03.91.9-1.91.9-2.01.71.9-1.71.4-1.41.91.8-1.8-1.61.2-1.8-1.81.6-1.6-1.8-1.8-1.8-1.6
Locomotion velocity, session 80.20.20.50.4-0.40.4-0.40.20.4-0.50.5-0.10.40.4-0.5-0.50.7-0.4-0.50.5-0.5-0.3-0.5-0.5-0.5
Locomotion distance, session 80.81.23.9-1.31.3-1.31.3-1.5-1.20.9-1.10.1-0.9-0.80.91.00.31.01.0-1.01.02.01.00.71.1
Degree of sensitization distance0.40.40.90.6-0.50.6-0.50.70.6-0.41.00.00.20.2-0.3-0.6-0.3-0.5-0.50.8-0.8-0.9-0.5-0.5-0.9
Degree of sensitization stereotypy1.21.32.41.3-1.31.3-1.41.31.3-1.10.8-1.11.21.2-1.2-0.90.5-1.2-1.11.0-1.0-1.5-1.1-1.1-0.9
Condit. Reinf. active minus inactive responses0.40.41.3-0.70.8-0.70.8-1.1-0.70.5-0.30.5-0.6-0.60.60.40.00.60.5-0.40.31.00.60.70.3
Condit. Reinf. active-inactive response ratio0.10.10.7-0.00.00.0-0.0-0.40.1-0.30.3-0.30.20.2-0.2-0.30.6-0.1-0.30.3-0.30.8-0.1-0.1-0.2
Condit. Reinf. active responses1.11.32.3-1.31.3-1.31.4-1.5-1.21.0-0.80.8-1.2-1.11.21.0-0.61.31.1-0.90.91.31.31.30.9
Condit. Reinf. inactive responses3.64.35.5-2.32.2-2.32.2-1.9-2.12.1-1.81.7-2.2-2.22.22.1-2.12.32.1-2.02.01.32.32.21.9
Incentive salience index mean0.00.00.3-0.10.1-0.10.3-0.6-0.20.10.10.4-0.2-0.20.2-0.00.30.10.10.1-0.10.30.10.2-0.2
Condit. Reinf. lever presses0.10.20.60.5-0.40.40.1-0.10.1-0.10.40.8-0.00.0-0.1-0.40.7-0.5-0.10.3-0.4-0.5-0.4-0.4-0.6
Time in familiar zone, hab. session 10.20.20.6-0.60.5-0.50.5-0.5-0.50.4-0.40.3-0.4-0.40.40.40.00.40.4-0.40.40.80.50.40.4
Time in novel zone, hab. session 10.20.21.60.4-0.40.4-0.40.60.4-0.10.2-0.20.10.1-0.2-0.2-0.5-0.2-0.20.2-0.2-1.3-0.2-0.2-0.3
Total zone transitions, hab. session 10.40.51.2-0.80.8-0.80.9-1.1-0.80.7-0.60.9-0.7-0.70.70.7-0.10.80.7-0.60.60.80.80.40.6
Total locomotion distance, hab. session 10.10.21.3-0.50.6-0.50.5-1.1-0.40.2-0.30.1-0.2-0.10.20.20.60.20.3-0.20.21.10.2-0.00.2
Locomotion velocity, hab. session 10.10.21.3-0.50.5-0.40.3-1.0-0.20.0-0.2-0.20.00.10.00.20.60.10.1-0.10.01.10.1-0.10.2
Time in familiar zone, hab. session 20.10.10.20.1-0.10.1-0.10.40.1-0.20.1-0.40.30.2-0.2-0.30.3-0.3-0.20.1-0.10.3-0.20.3-0.2
Time in novel zone, hab. session 20.10.10.7-0.10.1-0.10.1-0.0-0.10.4-0.10.4-0.5-0.50.40.3-0.70.40.3-0.10.1-0.90.4-0.20.1
Total zone transitions, hab. session 20.40.52.6-0.90.9-0.90.7-1.4-0.60.3-0.20.6-0.4-0.30.40.50.60.60.3-0.20.21.60.70.20.4
Total locomotion distance, hab. session 20.50.73.3-1.11.2-1.10.8-1.5-0.70.4-0.40.3-0.4-0.40.50.60.40.80.4-0.40.41.80.90.50.6
Locomotion velocity, hab. session 20.40.53.5-0.91.0-0.90.6-1.4-0.40.1-0.20.1-0.2-0.10.20.30.70.60.2-0.10.11.90.60.20.4
Novel to familiar place preference ratio0.60.61.20.7-0.70.7-0.91.10.9-0.71.0-0.30.60.6-0.7-0.90.1-0.7-0.80.9-0.9-1.1-0.7-0.8-0.9
Novelty place preference0.30.30.80.4-0.40.4-0.60.80.6-0.40.7-0.00.30.3-0.4-0.6-0.1-0.4-0.50.6-0.6-0.9-0.5-0.5-0.7
Time in novel zone, NPP test0.20.21.00.4-0.40.4-0.50.80.5-0.30.6-0.10.20.2-0.3-0.5-0.3-0.4-0.40.5-0.4-1.0-0.4-0.4-0.6
Total zone transitions, NPP test1.31.85.3-1.61.7-1.61.5-2.3-1.41.1-1.21.0-1.1-1.01.11.4-0.01.31.1-1.11.12.21.40.81.3
Total locomotion distance, NPP test2.94.18.2-2.42.4-2.42.1-2.9-2.11.8-1.91.3-1.8-1.71.82.1-0.72.11.8-1.81.82.42.11.82.0
Locomotion velocity, NPP test1.92.76.8-2.02.1-2.01.7-2.6-1.71.3-1.41.2-1.4-1.31.41.6-0.21.71.4-1.41.32.41.71.31.6
Pavlov. Cond. lever latency0.10.21.5-0.10.1-0.1-0.50.50.5-0.40.2-1.20.50.4-0.4-0.1-0.40.0-0.40.3-0.30.30.10.1-0.0
Pavlov. Cond. magazine entry latency0.10.10.80.3-0.30.30.10.0-0.1-0.0-0.1-0.30.20.2-0.1-0.20.9-0.20.1-0.10.10.3-0.1-0.30.0
Pavlov. Cond. change in total contacts0.10.10.70.1-0.10.10.4-0.0-0.30.3-0.00.8-0.4-0.40.40.0-0.00.10.3-0.10.1-0.50.00.1-0.1
Pavlov. Cond. index score0.20.30.70.8-0.80.8-0.20.50.3-0.20.20.10.30.3-0.3-0.50.8-0.6-0.20.3-0.3-0.7-0.6-0.7-0.4
Pavlov. Cond. latency score0.10.20.60.7-0.60.6-0.00.20.1-0.10.10.40.10.1-0.1-0.30.8-0.5-0.00.1-0.1-0.6-0.5-0.6-0.3
Pavlov. Cond. lever contacts0.40.52.1-0.30.4-0.30.9-0.8-0.80.8-0.71.4-0.8-0.80.80.6-0.10.40.8-0.70.7-0.10.40.40.5
Pavlov. Cond. magazine entry number0.00.10.5-0.40.4-0.4-0.0-0.10.00.00.10.1-0.1-0.10.10.2-0.70.2-0.00.1-0.00.00.20.30.0
Pavlov. Cond. intertrial magazine entries0.70.91.4-1.21.1-1.11.0-0.9-0.90.9-0.70.7-1.0-1.01.00.9-0.71.00.9-0.80.80.91.01.00.8
Pavlov. Cond. lever-magazine prob. diff.0.60.81.51.2-1.21.2-0.70.90.7-0.70.6-0.30.80.7-0.7-0.91.1-1.0-0.70.7-0.7-0.9-1.0-1.1-0.8
Pavlov. Cond. response bias0.00.10.40.2-0.20.20.3-0.2-0.30.2-0.30.3-0.1-0.10.10.00.7-0.10.3-0.30.30.1-0.1-0.10.1
Bone: apparent density6.510.814.12.9-3.03.0-3.22.33.3-3.73.5-3.43.53.6-3.5-3.63.8-3.4-3.53.5-3.5-0.3-3.4-3.2-3.3
Bone surface8.314.718.13.7-3.73.7-3.83.04.0-4.14.2-3.03.93.9-4.0-4.23.7-4.1-4.04.2-4.2-1.6-4.1-4.0-4.2
Bone volume5.28.911.52.7-2.72.8-2.82.23.0-3.23.4-2.63.13.1-3.1-3.43.2-3.2-3.23.3-3.3-0.7-3.2-3.0-3.2
Bone: connectivity density5.07.910.42.7-2.72.7-2.72.12.8-3.03.0-2.52.93.0-2.9-3.13.2-3.0-2.93.0-3.0-0.8-3.0-2.9-2.9
Bone: cortical apparent density0.91.23.2-0.91.1-1.01.4-1.8-1.31.2-0.81.8-1.4-1.31.31.1-0.20.81.2-0.90.90.30.80.60.7
Bone: cortical area8.112.215.13.2-3.23.2-3.52.53.7-3.93.9-2.83.73.8-3.8-3.93.7-3.5-3.83.9-3.9-0.9-3.5-3.7-3.7
Bone: cortical porosity1.71.82.8-1.21.2-1.21.3-0.7-1.41.5-1.71.0-1.4-1.41.41.4-1.41.41.5-1.61.60.41.41.41.6
Bone: cortical porosity1.71.93.3-1.11.1-1.11.3-0.8-1.51.6-1.81.0-1.3-1.41.41.5-1.31.31.6-1.71.70.41.31.31.6
Bone: cortical thickness3.45.710.52.0-2.02.0-2.31.22.4-2.72.6-1.92.62.7-2.6-2.63.2-2.4-2.62.6-2.60.2-2.4-2.7-2.4
Bone: cortical thickness0.40.54.7-0.40.4-0.40.1-0.80.1-0.60.5-0.60.40.5-0.4-0.41.6-0.0-0.40.5-0.52.2-0.0-0.3-0.2
Bone: cortical tissue density1.11.43.4-1.01.1-1.01.5-1.8-1.41.3-0.91.8-1.5-1.41.41.2-0.30.91.3-1.01.00.30.90.70.8
Bone: elastic displacement2.93.36.1-1.71.7-1.71.5-1.0-1.81.9-2.50.6-1.6-1.61.72.0-1.91.91.9-2.22.30.81.92.02.4
Bone: elastic work0.10.10.50.2-0.20.2-0.20.2-0.0-0.1-0.4-0.70.30.2-0.2-0.10.4-0.20.0-0.20.20.1-0.2-0.00.3
Bone: endosteal estimation6.714.417.03.9-3.93.9-4.04.04.1-3.84.1-3.13.73.7-3.8-4.02.2-3.8-3.94.1-4.0-3.3-3.8-3.7-4.1
Bone: endosteal perimeter6.012.314.73.5-3.53.5-3.73.53.8-3.63.8-3.13.53.5-3.6-3.82.3-3.5-3.73.8-3.8-2.3-3.5-3.4-3.7
Bone: final force8.113.216.63.6-3.53.6-3.62.73.7-3.94.1-2.83.73.8-3.8-3.93.7-3.9-3.84.0-4.0-1.5-3.9-3.8-4.0
Bone: final moment8.113.416.73.6-3.53.6-3.52.73.7-3.94.1-2.93.73.7-3.8-4.03.7-3.9-3.84.0-4.0-1.4-3.9-3.8-4.0
Bone: marrow area6.814.717.44.0-4.03.9-4.14.14.2-3.84.1-3.23.83.7-3.8-4.02.2-3.8-4.04.1-4.1-3.3-3.8-3.7-4.1
Bone: maximum diameter3.97.29.42.6-2.62.6-2.92.63.0-2.83.1-1.82.72.7-2.8-2.91.9-2.6-2.93.0-3.0-1.8-2.5-2.8-2.9
Bone: maximum force10.117.522.24.1-4.04.1-4.23.34.4-4.44.7-3.24.24.3-4.3-4.54.0-4.3-4.44.6-4.6-2.0-4.4-4.3-4.6
Bone: maximum moment10.017.422.14.1-4.04.1-4.13.34.3-4.44.7-3.44.24.2-4.3-4.64.0-4.3-4.44.6-4.6-1.9-4.4-4.3-4.6
Bone: minimum diameter6.311.714.73.3-3.23.3-3.63.03.7-3.73.8-2.83.63.6-3.6-3.82.8-3.4-3.73.8-3.8-1.7-3.4-3.5-3.6
Bone: periosteal estimation10.120.625.04.4-4.44.4-4.84.14.9-4.85.0-3.84.74.7-4.7-4.93.6-4.5-4.95.0-5.0-2.6-4.5-4.7-4.9
Bone: periosteal perimeter9.115.119.23.6-3.63.6-4.03.04.1-4.34.4-3.54.14.1-4.1-4.33.7-3.8-4.34.3-4.3-1.3-3.8-4.0-4.1
Bone: post-yield work7.710.512.63.5-3.43.5-3.33.13.4-3.23.5-2.43.13.1-3.2-3.32.3-3.5-3.23.4-3.4-2.6-3.5-3.4-3.5
Bone: stiffness12.019.025.04.3-4.24.3-4.33.64.6-4.65.0-3.44.44.4-4.5-4.83.8-4.4-4.64.8-4.9-2.3-4.5-4.4-4.9
Bone: tissue strength0.40.41.50.8-0.80.8-0.50.70.5-0.40.5-0.00.40.4-0.4-0.60.3-0.8-0.40.5-0.5-1.2-0.8-0.6-0.7
Bone: trabecular number3.65.610.02.1-2.12.1-2.21.42.3-2.72.5-2.52.52.6-2.6-2.63.2-2.5-2.52.5-2.50.2-2.5-2.2-2.4
Bone: trabecular spacing1.01.34.9-0.60.6-0.60.80.1-0.91.4-1.11.3-1.3-1.31.21.3-2.21.11.2-1.11.2-1.41.10.81.0
Bone: trabecular thickness0.80.95.5-1.21.2-1.21.0-1.4-0.90.5-0.7-0.0-0.6-0.50.60.60.50.80.7-0.70.72.30.81.00.8
Bone: trabecular tissue density0.30.42.3-0.50.6-0.50.7-0.9-0.60.7-0.41.5-0.8-0.80.70.7-0.30.50.7-0.40.4-0.20.50.30.3
Breakpoint value in progressive ratio session1.21.42.51.4-1.51.5-1.41.61.1-1.00.6-1.31.41.3-1.3-0.90.6-1.4-1.00.6-0.6-1.1-1.4-1.4-0.5
Distance traveled before self-admin0.50.51.6-0.60.6-0.60.4-0.1-0.60.6-1.00.0-0.4-0.50.50.9-1.30.60.7-1.01.00.60.70.51.1
Distance traveled after self-admin0.50.53.10.8-0.80.8-0.61.00.4-0.5-0.3-1.80.90.9-0.7-0.40.6-0.9-0.4-0.0-0.00.3-0.8-0.90.1
Delta time in closed arm before/after self-admin0.00.00.20.2-0.20.1-0.10.00.2-0.10.4-0.30.10.1-0.1-0.20.10.0-0.20.3-0.3-0.1-0.1-0.2-0.3
Delta time in open arm before/after self-admin2.52.43.9-1.51.5-1.51.5-1.4-1.71.6-2.01.2-1.5-1.51.51.7-1.51.21.7-1.81.81.11.41.41.8
Diff in mean of infusions in LGA sessions0.80.93.20.7-0.70.7-0.70.20.8-1.11.2-0.91.01.0-1.0-1.21.8-1.1-1.01.0-1.10.5-1.0-0.7-1.0
Extinction: sum of active levers before priming1.61.62.41.5-1.51.5-1.51.51.3-1.20.7-1.51.51.4-1.3-1.00.4-1.3-1.20.9-0.9-0.8-1.4-1.4-0.8
Active lever presses in extinction session 60.30.30.6-0.0-0.10.0-0.70.20.7-0.80.8-0.50.70.7-0.7-0.3-0.0-0.1-0.80.7-0.70.4-0.0-0.1-0.4
Delta distance traveled before/after self-admin0.40.41.20.6-0.60.6-0.60.70.6-0.60.3-1.00.80.8-0.7-0.61.1-0.6-0.60.5-0.5-0.1-0.6-0.5-0.5
Delta ambulatory time before/after self-admin0.30.30.70.6-0.60.6-0.50.70.5-0.50.2-0.70.60.6-0.6-0.50.9-0.5-0.50.4-0.4-0.4-0.6-0.3-0.4
Time in closed arm before self-admin0.30.31.1-0.30.2-0.2-0.3-0.10.5-0.61.00.50.30.4-0.5-0.50.5-0.2-0.71.0-1.00.40.1-0.3-0.8
Time in closed arm after self-admin0.10.10.5-0.20.2-0.2-0.3-0.10.4-0.30.70.10.10.1-0.2-0.1-0.50.3-0.40.5-0.5-0.10.40.5-0.3
Time in open arm before self-admin0.70.82.90.9-0.90.8-1.01.31.0-0.71.2-0.90.50.5-0.6-0.8-0.1-0.3-0.80.9-0.9-1.7-0.5-0.8-1.0
Time in open arm after self-admin0.40.40.8-0.60.6-0.50.7-0.5-0.70.8-0.50.7-0.9-0.90.80.6-0.70.60.8-0.60.6-0.10.50.10.4
Sum of active levers in priming session hrs 5-60.20.21.50.6-0.60.6-0.10.7-0.00.2-0.40.1-0.0-0.10.10.1-0.3-0.40.2-0.30.3-1.2-0.4-0.20.2
Time to tail flick, vehicle, before self-admin0.40.41.1-0.40.4-0.40.7-0.9-0.80.6-1.0-0.4-0.3-0.40.50.50.2-0.10.8-1.01.01.0-0.10.50.9
Time to tail flick, vehicle, after self-admin0.10.10.40.1-0.20.1-0.00.70.00.10.2-0.2-0.2-0.20.2-0.1-0.60.10.1-0.10.1-0.6-0.00.0-0.0
Time to tail flick, test, before self-admin0.90.92.2-1.11.1-1.10.8-1.1-0.90.6-0.90.2-0.7-0.70.70.9-0.51.00.7-0.90.81.41.01.51.0
Time to tail flick, test, after self-admin0.20.21.30.00.0-0.0-0.10.40.10.20.40.2-0.4-0.50.3-0.0-0.90.20.10.2-0.2-1.10.30.4-0.4
Delta time to tail flick, vehicle, before/after SA0.40.42.60.8-0.80.7-0.61.60.6-0.30.5-0.50.30.3-0.4-0.6-0.3-0.4-0.40.4-0.4-1.3-0.4-0.5-0.5
Delta time to tail flick, test, before/after SA0.30.32.30.2-0.20.3-0.10.50.30.20.70.7-0.4-0.40.2-0.3-0.5-0.2-0.00.5-0.4-1.5-0.0-0.4-0.8
Ambulatory time before self-admin2.42.54.6-1.61.5-1.51.2-0.9-1.51.5-2.00.5-1.3-1.31.41.9-2.11.61.5-1.91.91.11.81.62.1
Ambulatory time after self-admin0.30.31.80.3-0.20.2-0.00.6-0.30.3-1.3-1.30.30.2-0.00.6-0.4-0.10.4-0.90.90.30.00.01.0
Total heroin consumption3.13.85.62.0-2.01.9-2.22.42.1-1.91.9-2.22.02.0-2.0-1.71.1-1.8-2.01.9-1.8-1.8-1.8-2.1-1.8
Area under the delay curve0.80.92.90.4-0.50.6-0.5-0.10.8-1.01.30.30.80.9-0.9-1.11.7-0.8-1.01.2-1.30.7-0.8-1.2-1.2
Delay disc. indifference point, 0s delay0.70.71.90.1-0.20.3-0.6-0.20.9-1.01.40.30.80.9-0.9-0.91.1-0.4-1.11.3-1.30.6-0.5-0.9-1.1
Delay disc. indifference point, 16s delay1.11.11.90.9-1.01.1-0.90.61.0-1.11.3-0.10.91.0-1.0-1.21.3-1.0-1.11.3-1.3-0.5-1.0-1.3-1.4
Delay disc. indifference point, 2s delay0.30.31.1-0.10.10.0-0.1-0.30.4-0.61.10.70.30.3-0.4-0.70.8-0.4-0.50.9-0.90.7-0.5-0.5-0.9
Delay disc. indifference point, 24s delay0.90.81.60.6-0.70.8-0.90.71.0-1.01.30.40.90.9-0.9-1.00.7-0.8-1.11.2-1.2-0.7-0.7-1.0-1.2
Delay disc. indifference point, 4s delay0.20.21.10.1-0.10.10.1-0.40.2-0.30.70.20.20.2-0.2-0.61.1-0.4-0.30.6-0.60.9-0.4-0.2-0.7
Delay disc. indifference point, 8s delay2.52.64.91.1-1.21.3-1.30.61.6-1.92.0-0.91.61.7-1.7-1.72.2-1.3-1.82.1-2.10.4-1.4-2.0-1.9
Delay discount exponential model param0.70.72.4-0.40.5-0.50.40.1-0.70.9-1.2-0.3-0.7-0.80.81.0-1.50.80.9-1.11.1-0.70.81.11.1
Delay discount hyperbolic model param0.60.62.2-0.30.4-0.50.30.1-0.60.8-1.2-0.4-0.6-0.70.71.0-1.50.70.8-1.11.1-0.70.71.01.1
Fecal boli incidents, locomotor time 11.01.17.5-1.01.1-1.01.2-1.8-1.10.6-0.81.0-0.6-0.50.60.61.20.30.8-0.70.72.70.30.20.8
Change in fecal boli incidents, locomotor task0.70.63.80.8-0.80.7-0.91.10.9-0.60.9-0.30.50.4-0.5-0.7-0.8-0.3-0.70.7-0.7-2.0-0.50.2-0.8
Time >=10cm from walls, locomotor time 11.01.02.10.5-0.50.6-0.9-0.10.9-1.20.7-1.01.31.4-1.3-0.91.4-1.0-1.10.9-1.01.2-1.1-1.1-0.6
Bouts of movement, locomotor time 10.20.31.60.3-0.30.3-0.1-0.10.2-0.40.50.60.30.4-0.3-0.41.2-0.4-0.40.5-0.50.4-0.3-1.3-0.4
Total resting periods, locomotor time 10.10.20.8-0.20.2-0.20.4-0.6-0.30.1-0.10.9-0.2-0.20.20.10.70.10.2-0.10.10.80.2-0.70.1
Rest time, locomotor task time 10.00.00.3-0.10.0-0.1-0.20.10.00.0-0.20.50.10.0-0.00.2-0.5-0.10.0-0.20.2-0.4-0.00.10.3
Distance moved, locomotor task time 10.10.11.4-0.10.1-0.1-0.0-0.1-0.1-0.1-0.6-1.20.30.3-0.20.20.20.3-0.0-0.20.20.90.10.00.4
Vertical activity count, locomotor time 11.31.43.50.9-0.80.9-0.90.21.0-1.41.0-1.81.41.4-1.3-1.11.9-0.9-1.31.2-1.21.1-1.1-1.0-0.9
Time >=10cm from walls, locomotor time 20.10.10.5-0.00.00.00.0-0.3-0.20.0-0.4-0.50.20.2-0.10.20.10.10.1-0.40.40.7-0.1-0.10.5
Bouts of movement, locomotor time 23.23.45.02.2-2.22.2-1.92.11.9-1.72.0-1.51.61.6-1.7-1.80.9-1.3-1.82.0-1.9-1.8-1.7-2.2-2.0
Total resting periods, locomotor time 22.93.04.62.0-2.02.0-1.81.91.9-1.72.0-1.21.51.5-1.6-1.70.8-1.1-1.82.0-1.9-1.7-1.5-2.1-1.9
Rest time, locomotor task time 20.10.11.20.1-0.00.0-0.2-0.10.2-0.10.41.1-0.1-0.1-0.0-0.3-0.2-0.3-0.10.3-0.3-1.1-0.10.2-0.5
Distance moved, locomotor task time 20.20.22.50.1-0.20.2-0.10.4-0.1-0.1-0.7-1.60.40.4-0.30.20.2-0.20.0-0.50.50.8-0.1-0.40.6
Vertical activity count, locomotor time 20.60.61.20.9-0.90.9-0.90.90.7-0.80.5-1.10.90.9-0.9-0.70.6-0.9-0.70.5-0.5-0.2-0.9-0.9-0.5
Weight adjusted by age0.91.03.00.2-0.20.2-0.6-0.50.9-1.11.7-0.40.80.9-0.9-1.11.7-0.4-1.11.5-1.50.9-0.6-1.0-1.4
Seeking ratio, delayed vs. immediate footshock0.10.10.60.3-0.30.3-0.2-0.20.3-0.40.40.10.30.3-0.3-0.40.7-0.4-0.40.5-0.50.6-0.40.0-0.5
Locomotion in novel chamber0.30.40.90.4-0.30.3-0.60.00.7-0.81.00.00.60.6-0.6-0.80.5-0.6-0.80.9-0.9-0.4-0.6-0.3-0.9
Locomotion in novel chamber post-restriction0.50.61.50.8-0.80.8-0.80.90.8-0.70.80.20.70.7-0.7-0.80.5-1.0-0.80.9-0.9-1.2-0.8-0.7-0.9
Progressive ratio0.00.10.20.2-0.10.1-0.30.20.2-0.30.0-0.00.40.4-0.4-0.10.2-0.2-0.30.1-0.20.2-0.20.3-0.0
Food seeking constrained by brief footshock0.70.92.21.0-1.11.0-1.11.40.8-0.8-0.0-1.51.21.2-1.1-0.60.8-1.0-0.80.3-0.3-0.7-0.8-1.0-0.2
Seeking ratio, punishment vs. effort0.10.10.70.5-0.60.5-0.30.60.2-0.10.0-0.50.10.1-0.1-0.20.1-0.3-0.10.1-0.1-0.8-0.3-0.8-0.2
Run reversals in cocaine runway, females0.30.31.4-0.50.5-0.50.0-0.3-0.20.3-0.4-0.2-0.2-0.20.30.6-1.00.70.2-0.50.50.50.71.20.8
Run reversals in cocaine runway, males2.62.58.5-1.91.7-1.71.8-2.9-1.61.3-1.02.5-1.5-1.41.41.10.31.11.4-1.11.12.41.21.11.1
Latency to leave start box in cocaine runway0.20.21.6-0.30.4-0.30.4-0.3-0.30.4-0.11.3-0.5-0.50.40.3-0.40.30.3-0.10.1-0.60.30.20.0
Latency to leave start box in cocaine runway, F1.71.93.4-1.41.4-1.41.4-1.2-1.41.4-1.41.8-1.4-1.41.41.4-1.21.21.4-1.41.40.51.21.51.4
Latency to leave start box in cocaine runway, M1.91.82.61.5-1.41.5-1.31.31.4-1.31.5-0.71.21.3-1.3-1.30.9-1.2-1.41.5-1.5-1.6-1.2-1.6-1.6
Cd content in liver0.91.02.6-1.01.1-1.01.1-1.0-1.01.1-0.51.6-1.2-1.21.20.9-0.81.01.0-0.70.70.21.01.00.5
Co content in liver0.30.41.3-0.60.6-0.60.8-1.1-0.70.5-0.60.6-0.5-0.40.50.50.20.40.6-0.50.51.00.30.40.6
Cu content in liver2.02.54.51.7-1.71.7-1.92.11.7-1.51.3-1.91.71.6-1.6-1.40.3-1.4-1.61.4-1.4-1.5-1.6-1.4-1.4
Fe content in liver0.20.22.20.1-0.10.1-0.30.80.1-0.0-0.4-1.50.30.2-0.10.1-0.80.1-0.0-0.20.30.20.00.20.4
K content in liver1.01.01.80.7-0.60.7-0.80.20.9-1.21.3-0.71.01.0-1.0-0.91.3-1.0-1.11.2-1.30.5-0.9-1.0-1.2
Mg content in liver0.10.10.9-0.20.3-0.2-0.0-0.40.1-0.20.2-0.00.20.2-0.20.10.30.1-0.20.2-0.20.90.20.10.0
Mn content in liver0.10.10.30.4-0.40.4-0.10.30.2-0.20.50.10.10.1-0.1-0.40.3-0.4-0.20.4-0.4-0.5-0.3-0.3-0.6
Na content in liver0.40.41.80.6-0.60.6-0.81.20.7-0.50.5-1.30.60.5-0.5-0.4-0.5-0.2-0.60.5-0.5-0.8-0.1-0.1-0.4
Rb content in liver0.10.11.10.1-0.10.1-0.40.60.2-0.0-0.1-0.10.10.1-0.10.3-1.00.2-0.1-0.10.1-0.70.30.10.2
Se content in liver0.81.02.3-1.21.2-1.21.2-1.4-1.00.9-0.50.8-1.0-1.01.00.7-0.41.00.9-0.70.71.50.91.00.6
Sr content in liver1.21.12.61.2-1.31.2-1.11.61.1-0.80.9-1.10.90.8-0.9-1.00.1-1.0-0.90.9-0.9-1.5-1.0-1.0-1.0
Zn content in liver0.20.31.3-0.50.5-0.50.10.0-0.30.3-0.6-0.3-0.2-0.20.30.6-1.10.70.3-0.50.50.40.70.60.8