Fth1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000119519 0.07 0.04 2.1e-03 0.03 0.02 0.03 0.03 2.2e-04 1.5e-03 2.8e-04 2.9e-04
2 Adipose mRNA stability ENSRNOG00000022619 0.08 0.06 2.3e-03 0.01 0.02 0.01 0.01 1.4e-02 5.1e-03 9.1e-03 5.3e-02
3 BLA gene expression ENSRNOG00000022619 0.25 0.12 1.4e-15 0.25 0.27 0.26 0.27 7.8e-14 1.3e-14 1.8e-14 1.2e-14
4 BLA mRNA stability ENSRNOG00000022619 0.33 0.13 0.0e+00 0.29 0.33 0.3 0.31 1.1e-15 5.1e-18 8.5e-17 4.4e-17
5 Brain alternative polyA ENSRNOT00000094152 0.08 0.04 3.1e-09 0.1 0.1 0.1 0.1 3.9e-09 3.0e-09 4.2e-09 4.3e-09
6 Brain alternative polyA ENSRNOT00000119519 0.09 0.05 1.4e-09 0.1 0.1 0.09 0.1 3.1e-09 2.2e-09 1.6e-08 4.2e-09
7 Brain gene expression ENSRNOG00000022619 0.35 0.14 0.0e+00 0.39 0.37 0.38 0.38 8.0e-38 4.9e-36 5.1e-37 1.3e-37
8 Brain mRNA stability ENSRNOG00000022619 0.47 0.13 0.0e+00 0.53 0.54 0.55 0.55 1.4e-57 1.7e-59 4.0e-60 5.2e-60
9 IL gene expression ENSRNOG00000022619 0.54 0.22 1.7e-09 0.26 0.25 0.28 0.27 7.2e-07 9.5e-07 1.8e-07 2.8e-07
10 IL mRNA stability ENSRNOG00000022619 0.26 0.15 6.0e-06 0.19 0.22 0.17 0.21 2.2e-05 5.1e-06 5.6e-05 1.1e-05
11 LHb gene expression ENSRNOG00000022619 0.2 0.13 1.1e-03 0.13 0.08 0.11 0.1 4.6e-04 5.2e-03 1.7e-03 1.9e-03
12 LHb mRNA stability ENSRNOG00000022619 0.26 0.14 4.6e-05 0.17 0.13 0.16 0.19 6.2e-05 4.9e-04 1.4e-04 3.4e-05
13 Liver alternative polyA ENSRNOT00000094152 0.32 0.13 0.0e+00 0.16 0.19 0.19 0.19 1.9e-17 3.3e-20 9.3e-21 1.4e-20
14 Liver alternative polyA ENSRNOT00000119519 0.31 0.13 0.0e+00 0.16 0.18 0.18 0.18 4.2e-17 8.2e-20 7.5e-20 7.2e-20
15 Liver gene expression ENSRNOG00000022619 0.12 0.07 3.6e-06 0.04 0.04 0.04 0.04 1.1e-05 5.4e-05 5.5e-05 2.7e-05
16 Liver isoform ratio ENSRNOT00000030919 0.23 0.1 0.0e+00 0.16 0.16 0.16 0.16 2.8e-17 4.4e-17 8.9e-18 1.5e-17
17 Liver isoform ratio ENSRNOT00000094152 0.23 0.1 0.0e+00 0.17 0.17 0.18 0.18 6.1e-19 1.0e-18 2.0e-19 3.6e-19
18 Liver mRNA stability ENSRNOG00000022619 0.03 0.02 6.8e-04 0.01 0.01 0 0.01 2.2e-02 9.1e-03 1.4e-01 3.5e-02
19 NAcc gene expression ENSRNOG00000022619 0.11 0.06 3.3e-11 0.17 0.15 0.16 0.16 1.3e-12 2.4e-11 9.7e-12 6.4e-12
20 NAcc mRNA stability ENSRNOG00000022619 0.2 0.1 0.0e+00 0.25 0.25 0.24 0.25 1.1e-18 5.6e-19 1.2e-17 1.8e-18
21 OFC gene expression ENSRNOG00000022619 0.3 0.16 1.6e-05 0.15 0.15 0.13 0.14 2.4e-04 2.0e-04 5.9e-04 3.0e-04
22 OFC mRNA stability ENSRNOG00000022619 0.31 0.15 1.4e-06 0.19 0.18 0.19 0.22 2.3e-05 4.8e-05 3.0e-05 6.6e-06
23 PL gene expression ENSRNOG00000022619 0.23 0.1 0.0e+00 0.29 0.32 0.32 0.32 2.7e-22 7.7e-25 9.0e-25 3.9e-25
24 PL mRNA stability ENSRNOG00000022619 0.43 0.21 0.0e+00 0.39 0.42 0.42 0.41 2.6e-31 2.0e-34 2.9e-34 3.9e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
BMI with tail2.58.318.3-4.32.22.72.4-2.83.02.72.02.72.02.62.9-3.63.42.93.4-3.42.52.62.83.22.62.92.5
BMI without tail1.22.63.6-1.6-0.01.61.5-1.71.81.51.31.71.51.51.9-1.71.71.81.8-1.71.71.51.61.81.51.81.5
Body weight3.414.218.0-3.30.54.03.9-4.14.14.03.54.03.43.84.2-3.63.74.23.4-3.43.93.84.14.23.84.23.8
Epididymis fat weight0.51.12.9-1.61.7-1.0-1.01.0-0.9-0.9-1.3-1.1-1.4-1.1-0.80.3-0.4-0.9-0.70.7-1.1-1.1-0.8-0.7-1.1-0.9-1.0
Glucose2.94.46.8-0.71.4-2.2-2.32.2-2.1-2.3-2.6-2.3-2.5-2.4-2.01.7-1.8-2.0-1.81.8-2.3-2.4-2.1-2.0-2.4-2.2-2.2
Heart weight0.60.91.9-0.60.1-0.9-0.90.8-0.8-1.3-1.4-0.9-1.1-1.2-0.50.9-0.9-0.6-1.01.0-0.9-1.1-0.9-0.8-1.1-0.8-1.0
Left kidney weight0.10.21.5-1.21.00.20.3-0.20.30.2-0.10.2-0.20.10.4-0.30.20.40.00.00.10.20.40.40.20.30.3
Right kidney weight0.10.31.5-1.21.00.50.4-0.40.50.40.20.40.10.40.6-0.60.50.60.4-0.40.30.40.50.60.40.50.5
Tail length0.92.74.70.7-2.21.81.9-1.91.71.71.91.82.01.62.0-0.50.71.90.7-0.72.01.71.71.61.71.91.7
Length with tail1.97.19.4-1.1-0.63.03.1-3.02.92.92.82.92.72.83.0-2.02.23.11.9-1.82.92.82.92.92.83.12.9
Length without tail1.53.24.1-1.50.72.02.0-1.91.91.91.81.91.51.91.8-1.51.62.01.4-1.41.81.92.02.01.91.91.9
Liver weight, left0.50.92.20.4-0.1-0.8-0.70.9-0.9-0.7-0.8-0.9-0.9-0.9-0.71.5-1.3-0.8-1.51.5-0.8-0.9-0.8-0.9-0.9-0.9-0.8
Liver weight, right0.10.10.7-0.90.8-0.2-0.30.2-0.1-0.1-0.3-0.2-0.4-0.2-0.20.4-0.3-0.2-0.30.3-0.3-0.1-0.2-0.1-0.2-0.1-0.3
Parametrial fat weight1.63.15.7-1.02.4-1.8-1.91.9-1.8-1.6-2.1-2.0-2.4-1.7-1.80.7-0.9-1.8-1.21.2-2.1-1.9-1.7-1.6-1.9-1.9-1.9
Retroperitoneal fat weight2.37.711.9-1.32.1-2.8-2.72.8-2.8-2.9-3.4-3.0-3.4-3.1-2.52.4-2.5-2.5-2.82.8-3.0-3.2-2.6-2.5-3.2-2.8-2.7
Intraocular pressure0.10.21.41.2-1.0-0.4-0.40.4-0.4-0.4-0.2-0.4-0.1-0.4-0.40.1-0.2-0.4-0.0-0.0-0.3-0.5-0.4-0.5-0.5-0.4-0.3
Extensor digitorum longus weight5.923.726.8-2.9-0.15.14.9-5.15.25.14.95.04.75.05.0-5.15.25.15.1-5.15.05.05.15.25.05.15.0
Soleus weight2.67.59.01.00.9-2.8-2.93.0-2.9-2.8-2.8-2.9-2.9-2.8-3.02.6-2.7-2.9-2.72.7-3.0-2.9-2.9-2.9-2.9-3.0-2.9
Tibialis anterior weight9.532.938.9-1.8-1.66.26.1-6.16.16.16.16.16.16.06.1-5.05.46.25.4-5.46.26.06.16.06.06.16.2
Tibia length1.33.75.4-1.01.12.02.0-1.91.92.32.12.01.62.21.7-1.91.91.81.7-1.71.82.32.12.12.32.02.0
Number of licking bursts0.00.00.0-0.10.1-0.00.00.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.10.10.00.1-0.1-0.1-0.20.0-0.0-0.2-0.10.0
Food consumed during 24 hour testing period0.30.30.60.60.2-0.6-0.60.6-0.6-0.3-0.3-0.5-0.5-0.3-0.80.7-0.8-0.7-0.80.8-0.6-0.5-0.6-0.6-0.5-0.7-0.7
Times rat made contact with spout0.20.21.30.7-1.20.40.4-0.40.40.40.50.40.70.30.40.10.00.50.1-0.10.50.40.30.30.40.40.3
Mean time between licks in bursts0.60.81.4-0.4-1.21.00.8-1.01.00.80.80.91.10.71.1-0.80.91.21.1-1.11.10.60.80.90.60.90.9
Mean num. licks in bursts0.10.11.00.9-1.0-0.1-0.10.0-0.1-0.10.10.00.3-0.1-0.00.5-0.4-0.1-0.30.20.1-0.0-0.2-0.2-0.0-0.0-0.2
Std. dev. time between licks in bursts0.20.20.4-0.3-0.1-0.4-0.40.4-0.4-0.4-0.5-0.4-0.4-0.5-0.30.7-0.7-0.3-0.60.6-0.4-0.6-0.5-0.4-0.6-0.4-0.5
Water consumed over 24 hours0.20.30.50.4-0.70.60.6-0.60.50.50.70.60.60.60.6-0.20.30.60.2-0.10.60.60.50.50.60.60.4
Indifference point 0 sec0.50.81.2-0.3-0.21.01.1-1.01.01.01.01.00.91.11.1-0.60.71.10.6-0.61.00.91.11.00.90.81.1
Indifference point AUC1.82.13.3-0.0-0.11.41.6-1.41.41.61.61.61.51.81.4-1.11.31.31.2-1.21.41.81.61.41.81.51.6
Indifference point function ln k3.14.46.7-0.61.1-2.2-2.52.2-2.1-2.3-2.5-2.3-2.4-2.5-2.11.2-1.5-1.9-1.41.4-2.3-2.6-2.3-2.1-2.6-2.3-2.5
Indifference point function log k3.14.46.7-0.61.1-2.2-2.52.2-2.1-2.3-2.5-2.3-2.4-2.5-2.11.2-1.5-1.9-1.41.4-2.3-2.6-2.3-2.1-2.6-2.3-2.5
Delay discounting total patch changes 0 sec0.50.81.2-0.2-0.51.01.1-1.01.01.01.01.01.01.01.1-0.40.51.10.5-0.41.00.91.01.00.90.81.1
Delay discounting total patch changes 12 sec6.48.510.8-0.2-1.53.13.3-3.13.13.23.23.23.33.33.2-2.22.53.12.4-2.43.23.13.13.03.13.03.2
Delay discounting total patch changes 18 sec0.50.71.30.3-0.60.91.0-0.90.80.91.01.01.01.10.9-0.20.50.90.4-0.40.91.00.90.81.10.91.0
Delay discounting total patch changes 24 sec7.08.810.7-1.4-0.43.13.2-3.23.23.03.03.22.93.33.3-2.62.83.22.7-2.63.13.13.23.23.13.23.2
Delay discounting total patch changes 6 sec0.91.42.2-0.6-0.11.31.4-1.31.31.31.31.31.11.51.4-0.70.91.50.7-0.71.31.21.41.31.31.11.3
Delay discounting time to switch 0 sec0.40.61.4-1.11.20.70.6-0.70.70.70.60.70.40.90.5-1.21.20.71.0-1.00.60.70.80.80.70.60.6
Delay discounting water rate 0 sec0.60.91.70.9-0.4-1.0-0.90.9-1.0-0.7-0.7-0.9-0.7-1.0-1.01.2-1.3-1.0-1.21.2-0.9-0.9-1.0-1.0-0.9-0.9-0.9
Delay discounting water rate 12 sec1.62.43.40.3-0.2-1.7-1.61.5-1.5-1.7-1.7-1.7-1.5-1.8-1.51.4-1.6-1.5-1.41.4-1.5-1.9-1.7-1.6-1.9-1.6-1.7
Delay discounting water rate 18 sec0.70.91.6-0.50.1-0.8-0.90.8-0.8-1.0-1.0-0.9-0.9-1.1-0.71.2-1.2-0.6-1.31.3-0.8-1.0-1.0-0.8-1.0-0.8-1.1
Delay discounting water rate 24 sec1.31.82.70.5-0.3-1.2-1.41.3-1.4-1.4-1.3-1.5-1.2-1.5-1.41.2-1.3-1.1-1.31.3-1.3-1.6-1.5-1.4-1.6-1.5-1.5
Delay discounting water rate 6 sec1.01.52.40.4-0.5-1.1-1.21.1-1.1-1.2-1.2-1.1-1.1-1.4-1.11.5-1.6-1.1-1.51.5-1.1-1.4-1.3-1.2-1.4-1.0-1.3
Locomotor activity0.71.13.30.6-1.0-0.9-0.70.8-0.9-1.0-1.0-0.8-0.7-1.2-0.41.8-1.6-0.6-1.61.6-0.7-1.2-0.9-0.9-1.2-0.8-0.7
Locomotor testing distance0.61.02.50.2-0.6-0.8-0.90.8-0.8-1.1-1.1-0.9-0.8-1.2-0.41.6-1.4-0.6-1.31.3-0.8-1.3-0.9-0.8-1.3-0.9-0.8
Locomotor testing rearing0.81.21.70.5-0.1-1.1-1.21.1-1.1-1.3-1.1-1.1-1.0-1.2-1.01.3-1.3-1.1-1.11.1-1.1-1.1-1.2-1.2-1.1-1.1-1.2
Light reinforcement 10.20.30.70.80.3-0.5-0.50.5-0.5-0.4-0.3-0.4-0.4-0.3-0.50.8-0.8-0.6-0.70.7-0.5-0.2-0.5-0.5-0.2-0.5-0.5
Light reinforcement 20.40.63.7-0.11.9-0.6-0.70.8-0.7-0.4-0.6-0.7-1.0-0.4-0.90.3-0.3-0.9-0.70.7-0.9-0.3-0.6-0.6-0.3-0.7-0.7
Reaction time number correct0.30.40.7-0.0-0.50.60.7-0.70.70.80.80.80.80.70.70.10.10.60.0-0.00.70.80.60.60.80.90.5
Reaction time mean minus median0.30.40.80.8-0.40.50.6-0.50.50.80.80.60.80.80.3-0.80.80.40.9-0.90.60.70.60.50.70.40.7
Reaction time mean minus median AUC0.20.31.91.4-1.20.20.4-0.30.20.40.60.30.70.40.1-0.30.40.10.5-0.50.40.30.30.10.30.10.4
Reaction time num false alarms0.30.42.20.7-1.5-0.2-0.20.2-0.3-0.6-0.4-0.3-0.1-0.5-0.01.1-1.10.1-0.90.9-0.1-0.5-0.4-0.4-0.5-0.2-0.4
Reaction time num false alarms AUC0.30.44.50.8-2.10.40.5-0.40.3-0.10.20.30.60.00.71.0-0.70.7-0.70.70.50.00.20.20.00.40.3
Reaction time trials correct on left0.30.40.7-0.0-0.50.60.7-0.70.70.80.80.80.80.70.70.10.10.60.0-0.00.70.80.60.60.80.90.5
Reaction time trials on left0.30.40.80.1-0.60.70.7-0.70.70.80.80.80.80.70.70.10.00.60.0-0.00.80.90.60.60.80.90.5
Reaction time mean0.10.10.50.70.2-0.3-0.20.2-0.20.20.2-0.10.10.1-0.5-0.60.5-0.50.7-0.7-0.20.2-0.2-0.20.2-0.3-0.1
Reaction time mean AUC0.20.20.60.70.5-0.5-0.50.4-0.40.0-0.0-0.4-0.2-0.1-0.8-0.50.4-0.80.5-0.5-0.4-0.1-0.4-0.5-0.1-0.5-0.4
Median of all reaction times0.10.20.70.20.6-0.0-0.0-0.00.10.40.30.10.10.3-0.3-0.80.8-0.30.8-0.80.00.40.10.00.4-0.00.0
Reaction time omissions0.20.21.81.2-1.30.30.4-0.30.20.40.50.30.60.40.30.2-0.10.3-0.10.10.40.20.20.10.20.20.3
Reaction time false alarm rate0.20.21.50.4-1.2-0.1-0.10.2-0.2-0.6-0.4-0.3-0.1-0.50.10.8-0.70.2-0.70.7-0.1-0.5-0.2-0.3-0.5-0.2-0.2
Reaction time premature initiation rate3.44.55.8-1.90.72.32.2-2.32.32.32.12.21.82.22.3-2.02.12.31.8-1.72.12.32.32.42.32.32.1
Reaction time premature initiations4.05.87.6-1.4-0.12.62.6-2.72.72.72.62.62.42.62.7-1.82.02.61.7-1.72.62.72.62.62.72.82.4
Std. dev. reaction times0.10.22.31.5-0.9-0.3-0.20.3-0.3-0.00.1-0.20.2-0.1-0.5-0.0-0.0-0.40.1-0.2-0.1-0.1-0.3-0.4-0.1-0.4-0.1
Reaction time trials completed0.30.40.80.1-0.60.70.7-0.70.70.80.80.80.80.70.70.10.00.60.0-0.00.80.90.60.60.80.90.5
Reaction time trials AUC0.20.30.6-0.0-0.50.60.6-0.60.60.70.70.70.70.60.60.2-0.00.5-0.00.10.70.70.50.50.70.80.4
Social response proportion0.10.10.6-0.30.30.30.3-0.30.20.30.30.30.10.40.30.7-0.40.3-0.70.80.20.40.20.30.40.30.0
Social responses0.20.21.00.7-1.00.10.4-0.20.10.20.40.30.40.30.21.0-0.80.2-0.90.90.30.20.10.00.20.20.1
Social time0.20.33.11.1-1.80.00.2-0.20.1-0.20.30.20.50.10.20.7-0.40.2-0.50.40.30.10.0-0.10.10.20.1
Conditioned locomotion0.60.81.1-0.4-0.51.01.0-1.00.90.90.80.90.90.81.0-0.70.81.00.8-0.81.00.81.00.90.80.91.0
Cocaine response after cond. corrected0.30.30.8-0.3-0.1-0.6-0.80.5-0.5-0.8-0.8-0.6-0.5-0.8-0.50.0-0.2-0.40.1-0.2-0.5-0.9-0.7-0.6-0.9-0.7-0.6
Cocaine response after cond. not corrected0.40.40.8-0.30.6-0.7-0.90.7-0.6-0.7-0.7-0.7-0.6-0.7-0.7-0.1-0.1-0.70.1-0.2-0.7-0.7-0.7-0.6-0.7-0.8-0.7
Cocaine response before conditioning0.20.21.60.41.30.10.2-0.10.10.60.60.30.10.7-0.2-0.40.4-0.30.2-0.20.00.80.20.20.80.20.2
Saline control response2.12.83.7-0.3-0.71.81.8-1.81.81.91.91.81.91.71.8-1.11.31.81.4-1.41.81.91.71.71.91.81.8
Condit. Reinf. active minus inactive responses0.30.40.90.70.7-0.7-0.80.7-0.7-0.5-0.5-0.6-0.6-0.4-0.9-0.1-0.0-0.90.1-0.1-0.7-0.4-0.6-0.7-0.4-0.7-0.6
Condit. Reinf. active-inactive response ratio0.50.51.4-0.11.2-0.8-0.80.7-0.7-0.6-0.8-0.7-0.8-0.6-0.9-0.90.6-0.90.7-0.7-0.8-0.6-0.6-0.6-0.6-0.7-0.6
Condit. Reinf. active responses0.00.00.30.30.5-0.2-0.20.2-0.2-0.00.0-0.1-0.10.1-0.3-0.10.1-0.40.2-0.2-0.20.1-0.2-0.20.1-0.1-0.2
Condit. Reinf. inactive responses0.10.11.00.20.00.10.1-0.10.00.10.30.20.10.3-0.01.0-0.7-0.0-0.80.80.10.3-0.1-0.00.30.1-0.2
Condit. Reinf. lever presses0.60.92.1-0.61.10.80.7-0.80.81.10.90.80.61.10.5-1.51.40.61.3-1.30.71.10.80.91.10.70.7
Condit. Reinf. lever reinforcers received0.10.10.40.40.40.10.1-0.10.10.30.40.20.20.4-0.1-0.60.6-0.10.6-0.60.10.50.10.10.50.20.1
Pavlov. Cond. lever latency0.50.73.01.0-1.4-0.5-0.30.5-0.6-0.8-0.5-0.5-0.3-0.7-0.31.7-1.5-0.3-1.51.5-0.4-0.8-0.5-0.7-0.8-0.5-0.4
Pavlov. Cond. magazine entry latency4.85.510.4-0.60.42.22.0-2.22.32.52.52.32.32.61.8-3.23.11.83.1-3.12.22.62.22.22.62.22.0
Pavlov. Cond. change in total contacts1.21.75.2-0.41.50.90.8-0.91.01.51.41.00.91.50.5-2.32.10.42.0-2.00.81.51.01.01.50.90.8
Pavlov. Cond. index score2.73.59.6-0.91.31.51.4-1.51.62.01.81.61.52.11.1-3.12.81.12.8-2.81.42.11.61.72.11.51.4
Pavlov. Cond. latency score2.53.29.0-1.01.51.41.3-1.51.61.91.71.51.31.91.1-3.02.71.12.7-2.71.32.01.51.62.01.51.3
Pavlov. Cond. lever contacts0.50.62.8-0.10.80.40.3-0.40.50.80.70.50.50.80.1-1.71.50.21.6-1.60.40.70.40.50.70.40.4
Pavlov. Cond. magazine entry number7.49.116.71.0-0.5-2.8-2.72.9-2.9-3.2-3.2-2.9-2.9-3.3-2.44.1-3.9-2.5-3.93.9-2.8-3.3-2.9-2.9-3.3-2.8-2.7
Pavlov. Cond. intertrial magazine entries1.72.24.10.9-0.1-1.4-1.31.5-1.5-1.7-1.5-1.4-1.4-1.5-1.32.0-1.9-1.3-1.91.9-1.4-1.5-1.4-1.5-1.5-1.4-1.3
Pavlov. Cond. lever-magazine prob. diff.3.03.910.1-0.81.31.61.5-1.61.72.12.01.71.62.21.2-3.22.91.22.9-2.91.62.21.71.72.21.61.5
Pavlov. Cond. response bias1.62.26.1-0.50.81.21.0-1.21.31.61.51.31.31.60.9-2.52.30.92.3-2.31.21.61.21.31.61.21.1
Conditioned reinforcement - actives1.91.93.01.10.4-1.5-1.61.5-1.5-1.4-1.3-1.5-1.3-1.3-1.70.9-1.1-1.7-1.01.0-1.5-1.4-1.6-1.5-1.4-1.5-1.6
Conditioned reinforcement - inactives0.80.92.1-0.31.4-1.1-1.11.0-1.0-0.8-1.0-1.0-1.2-0.8-1.00.1-0.3-1.2-0.30.3-1.1-1.0-1.0-0.9-0.9-1.1-1.1
Conditioned locomotion1.41.72.7-0.11.5-1.5-1.51.4-1.3-1.3-1.6-1.4-1.6-1.3-1.30.7-0.9-1.5-0.90.9-1.5-1.3-1.4-1.2-1.3-1.3-1.6
Intermittent access intake day 1-15 change1.21.22.21.3-0.1-1.3-1.11.2-1.2-0.9-0.8-1.0-0.9-1.0-1.31.2-1.2-1.5-1.11.1-1.1-0.7-1.2-1.3-0.7-1.0-1.1
Intermittent access intake escalation0.70.71.41.1-0.1-1.0-0.90.9-0.9-0.6-0.6-0.8-0.7-0.7-1.00.8-0.9-1.2-0.70.7-0.8-0.4-0.9-1.0-0.5-0.7-0.9
Intermittent access intake escalation 20.00.00.40.6-0.3-0.1-0.00.1-0.20.10.2-0.00.10.1-0.20.1-0.1-0.4-0.10.1-0.10.3-0.1-0.20.3-0.0-0.0
Intermitt. access day 1 inactive lever presses1.31.43.5-0.81.9-1.4-1.41.2-1.1-1.1-1.5-1.2-1.5-1.0-1.20.2-0.4-1.5-0.40.4-1.4-1.2-1.2-1.0-1.2-1.2-1.3
Intermitt. access day 15 inactive lever presses0.50.56.5-1.42.5-0.0-0.1-0.10.20.4-0.10.1-0.40.30.0-1.10.9-0.00.8-0.7-0.10.40.20.40.40.2-0.1
Intermitt. access escalation Index0.20.20.7-0.80.7-0.4-0.30.3-0.3-0.6-0.7-0.3-0.6-0.5-0.20.6-0.5-0.2-0.60.6-0.4-0.2-0.3-0.2-0.2-0.0-0.3
Intermittent access day 1 total infusions0.91.08.4-1.82.9-0.7-1.00.7-0.5-0.7-1.2-0.8-1.4-0.7-0.7-0.40.3-0.60.1-0.1-1.0-0.7-0.6-0.3-0.7-0.7-0.9
Intermittent access day 15 total infusions2.63.04.7-0.12.2-1.9-2.01.9-1.8-1.7-1.9-1.8-2.2-1.7-1.91.0-1.2-2.0-1.21.2-2.0-1.5-1.8-1.7-1.5-1.7-2.0
Intermittent access terminal intake (last 3 days)0.60.64.5-0.82.1-0.7-0.90.8-0.7-0.5-0.8-0.7-1.1-0.5-0.9-0.30.1-0.80.0-0.0-0.9-0.3-0.7-0.5-0.4-0.6-0.9
Intermittent access total infusions0.80.95.3-0.82.3-0.9-1.10.9-0.8-0.7-1.1-0.9-1.3-0.7-1.0-0.1-0.1-0.9-0.10.2-1.1-0.6-0.8-0.6-0.7-0.9-1.0
Intermittent access day 1 locomotion0.60.66.1-2.12.5-0.0-0.30.00.2-0.1-0.6-0.1-0.7-0.10.0-0.90.80.10.6-0.6-0.3-0.10.00.3-0.1-0.1-0.3
Intermittent access day 15 total locomotion0.40.44.3-1.22.1-0.3-0.40.1-0.00.2-0.4-0.2-0.5-0.0-0.2-1.10.9-0.30.8-0.8-0.3-0.1-0.10.1-0.1-0.3-0.3
Intermittent access total locomotion0.91.012.7-2.23.6-0.2-0.50.20.00.1-0.5-0.2-0.9-0.0-0.3-1.31.1-0.10.9-0.9-0.50.1-0.00.30.1-0.1-0.4
Intermittent access standard deviation0.90.91.91.4-0.7-1.2-1.11.0-1.1-0.9-0.7-1.0-0.6-1.0-1.10.4-0.7-1.3-0.40.3-0.9-0.9-1.2-1.2-0.9-1.1-1.1
Cocaine induced anxiety0.20.30.6-0.10.00.50.5-0.50.50.60.60.50.60.60.4-0.80.70.30.8-0.80.50.20.50.50.20.30.5
Post-drug Anxiety0.60.61.2-0.20.20.70.7-0.80.80.90.90.80.80.90.6-1.11.00.61.1-1.10.80.60.70.80.70.70.7
Baseline Anxiety1.01.11.8-0.3-0.41.11.0-1.11.11.01.11.11.11.01.1-0.90.91.11.0-1.01.11.41.01.11.31.31.0
Lifetime Intake0.70.73.6-1.01.9-0.8-1.00.8-0.7-0.8-1.1-0.9-1.2-0.7-0.8-0.1-0.0-0.8-0.10.1-1.0-0.7-0.8-0.6-0.7-0.8-1.0
Incentive Sensitization - Responses0.10.11.5-0.71.20.20.1-0.10.20.30.10.1-0.10.3-0.0-0.40.40.20.3-0.20.00.40.20.30.40.20.1
Incentive Sensitization - Breakpoint0.20.22.3-0.81.50.1-0.0-0.00.10.20.00.0-0.30.2-0.1-0.40.40.10.2-0.2-0.10.30.10.20.30.1-0.0
Progressive ratio test 1 active lever presses1.21.21.80.40.7-1.2-1.21.2-1.2-1.1-1.2-1.2-1.3-1.1-1.30.9-1.0-1.3-1.01.0-1.3-1.0-1.2-1.1-1.0-1.1-1.2
Progressive ratio test 1 breakpoint1.41.42.10.50.5-1.3-1.31.3-1.3-1.2-1.3-1.3-1.3-1.2-1.41.0-1.1-1.4-1.11.1-1.3-1.0-1.3-1.3-1.0-1.2-1.3
Progressive ratio test 1 inactive lever presses0.40.41.6-1.20.80.40.4-0.60.60.50.20.50.30.50.6-1.11.00.51.0-1.00.50.30.60.70.30.40.4
Progressive ratio test 2 active lever presses1.21.32.8-0.21.7-1.2-1.31.2-1.1-1.0-1.2-1.2-1.5-1.0-1.30.6-0.7-1.3-0.80.8-1.3-0.9-1.2-1.0-0.9-1.1-1.3
Progressive ratio test 2 breakpoint2.02.23.20.21.5-1.6-1.61.6-1.6-1.4-1.6-1.6-1.8-1.4-1.71.1-1.3-1.7-1.21.2-1.7-1.3-1.5-1.5-1.3-1.5-1.6
Progressive ratio test 2 inactive lever presses0.50.65.0-1.02.2-0.6-0.80.6-0.5-0.4-0.8-0.7-1.0-0.4-0.7-0.40.2-0.70.1-0.1-0.8-0.6-0.6-0.4-0.5-0.7-0.8
Total sessions with >9 infusions1.01.12.2-0.61.3-1.2-1.31.1-1.0-1.1-1.5-1.1-1.4-1.2-1.00.2-0.4-1.1-0.40.4-1.2-1.2-1.1-0.9-1.2-1.1-1.2
Short access day 1 total inactive lever presses0.70.71.5-0.71.2-0.8-1.00.9-0.8-1.0-1.2-0.9-1.2-0.9-0.80.4-0.5-0.9-0.50.5-1.0-0.9-0.8-0.7-0.9-0.8-1.0
Short access day 10 total inactive lever presses1.82.03.00.20.1-1.6-1.51.4-1.4-1.7-1.7-1.5-1.5-1.6-1.21.3-1.4-1.2-1.31.3-1.4-1.7-1.5-1.4-1.7-1.4-1.5
Short access day 1 total infusions0.60.71.3-0.60.7-0.8-1.00.8-0.7-0.9-1.1-0.9-1.0-0.9-0.70.3-0.4-0.7-0.30.3-0.9-1.1-0.8-0.7-1.1-1.0-0.9
Short access day 10 total infusions0.60.66.4-1.92.5-0.4-0.60.3-0.2-0.3-0.8-0.4-1.0-0.3-0.3-0.70.6-0.30.5-0.5-0.6-0.3-0.30.0-0.3-0.2-0.5
Short access total infusions0.30.31.9-1.31.4-0.4-0.60.4-0.3-0.5-0.8-0.5-0.7-0.5-0.3-0.30.2-0.30.2-0.2-0.5-0.5-0.4-0.2-0.5-0.4-0.6
Short access day 1 locomotion0.30.31.6-1.30.80.20.3-0.40.50.50.10.30.20.30.4-1.00.90.50.9-0.80.30.30.40.60.30.40.3
Short access day 10 total locomotion0.50.54.0-1.92.00.1-0.1-0.20.30.1-0.30.0-0.30.0-0.0-1.31.10.21.0-1.0-0.0-0.10.20.4-0.1-0.0-0.1
Short access total locomotion0.90.94.2-2.11.80.50.4-0.60.80.70.20.60.10.50.6-1.61.40.71.4-1.40.40.60.60.90.60.70.4
Compulsive drug intake1.11.15.90.6-2.41.11.1-1.11.00.51.11.11.40.81.2-0.10.31.40.4-0.41.30.70.90.80.71.01.0
One hour access (0.3 mA shock)3.13.65.20.01.8-2.0-2.22.1-2.0-2.1-2.2-2.1-2.3-1.9-2.01.2-1.3-2.1-1.31.3-2.2-1.9-2.0-1.9-1.9-2.0-2.1
One hour access (shock baseline)4.24.97.00.52.1-2.4-2.42.5-2.4-2.1-2.3-2.4-2.6-2.1-2.51.5-1.6-2.7-1.71.7-2.6-2.2-2.3-2.2-2.2-2.4-2.4
Number of responses in last shaping day0.10.10.6-0.4-0.80.20.3-0.40.40.30.20.40.40.20.5-0.10.10.20.2-0.20.40.20.30.30.20.50.2
Context. condit. distance diff. score0.10.10.2-0.40.1-0.4-0.40.3-0.3-0.4-0.4-0.3-0.3-0.4-0.2-0.20.0-0.30.1-0.1-0.3-0.3-0.4-0.3-0.3-0.3-0.5
Locomotion velocity, session 10.10.10.3-0.50.00.20.1-0.30.30.20.20.20.30.20.3-0.20.30.20.4-0.40.30.10.20.20.10.20.2
Locomotion distance, session 10.81.11.9-1.40.21.00.8-1.11.11.00.91.11.01.01.1-1.01.11.01.3-1.31.00.91.01.10.91.10.9
Locomotion velocity, session 23.03.54.2-1.40.12.01.9-2.02.02.01.81.91.82.01.9-2.02.02.02.0-2.01.91.82.02.01.81.91.9
Locomotion distance, session 20.50.71.4-0.7-0.70.80.7-0.90.90.60.60.90.90.61.1-0.90.91.01.1-1.21.00.50.80.90.50.90.9
Locomotion velocity, session 30.60.74.6-2.11.50.60.4-0.60.70.60.20.40.10.60.6-1.41.20.71.1-1.00.40.20.60.80.20.40.5
Locomotion distance, session 30.00.10.3-0.50.30.10.1-0.10.10.10.0-0.0-0.10.1-0.00.4-0.30.1-0.50.50.0-0.10.00.1-0.1-0.0-0.1
Stereotopy head waving bouts, day 30.20.23.0-1.71.00.1-0.0-0.20.3-0.1-0.40.1-0.2-0.10.4-0.40.40.40.4-0.40.0-0.20.20.4-0.20.20.1
Stereotopy head waving duration, day 30.10.11.3-1.10.20.10.0-0.20.2-0.2-0.30.1-0.1-0.20.4-0.60.50.40.5-0.50.1-0.20.20.3-0.20.20.2
Locomotion velocity, session 70.00.00.4-0.60.40.00.1-0.00.0-0.0-0.2-0.0-0.2-0.00.20.10.00.1-0.20.2-0.0-0.00.10.1-0.00.10.2
Locomotion distance, session 70.10.10.6-0.80.0-0.1-0.10.1-0.1-0.3-0.4-0.2-0.3-0.30.20.3-0.20.1-0.30.3-0.1-0.3-0.1-0.0-0.3-0.1-0.1
Stereotopy head waving bouts, day 70.30.30.6-0.50.50.40.5-0.50.50.60.50.50.40.60.4-0.80.80.40.7-0.70.40.50.60.60.50.50.6
Stereotopy head waving duration, day 71.92.33.0-0.80.21.61.6-1.61.61.71.61.61.41.71.5-1.41.41.51.3-1.31.51.71.71.61.71.61.6
Locomotion velocity, session 80.10.11.20.4-1.10.20.3-0.20.20.10.20.20.30.10.40.6-0.40.4-0.40.40.30.10.20.10.10.30.2
Locomotion distance, session 80.10.11.0-1.00.4-0.3-0.30.1-0.1-0.3-0.4-0.2-0.3-0.40.1-0.40.2-0.10.4-0.4-0.2-0.3-0.1-0.1-0.3-0.1-0.2
Degree of sensitization distance0.20.21.8-1.40.8-0.1-0.2-0.00.1-0.2-0.4-0.0-0.2-0.20.3-0.90.80.10.9-0.9-0.0-0.10.10.2-0.10.10.1
Degree of sensitization stereotypy1.01.11.7-0.20.41.01.1-1.01.01.31.21.11.01.30.8-1.31.20.81.2-1.21.01.31.11.11.31.01.1
Condit. Reinf. active minus inactive responses1.01.12.1-0.50.31.00.8-1.01.01.11.11.01.01.10.8-1.31.30.91.4-1.51.01.10.91.01.10.90.9
Condit. Reinf. active-inactive response ratio0.50.51.30.3-0.70.60.5-0.70.70.70.80.70.90.70.5-0.80.80.51.1-1.10.70.60.50.50.60.60.6
Condit. Reinf. active responses1.01.22.8-1.11.10.90.7-0.91.01.11.00.90.81.10.7-1.61.60.81.6-1.70.81.00.91.01.00.80.8
Condit. Reinf. inactive responses0.30.32.7-1.31.6-0.2-0.30.2-0.1-0.1-0.3-0.3-0.5-0.0-0.3-0.80.6-0.30.5-0.5-0.4-0.1-0.1-0.0-0.1-0.3-0.2
Incentive salience index mean1.01.21.7-1.21.01.10.9-1.01.11.21.11.10.91.20.9-1.21.31.01.3-1.31.01.21.11.21.21.01.0
Condit. Reinf. lever presses0.50.62.5-1.51.60.80.6-0.60.70.90.60.70.30.80.5-0.60.70.60.5-0.40.50.80.70.80.80.70.6
Time in familiar zone, hab. session 10.10.10.4-0.40.60.00.0-0.10.10.20.20.10.00.3-0.1-0.30.3-0.10.3-0.30.00.40.10.10.40.10.0
Time in novel zone, hab. session 11.41.42.00.8-0.4-1.2-1.21.2-1.2-1.3-1.2-1.2-1.0-1.3-1.11.1-1.3-1.1-1.11.1-1.1-1.4-1.2-1.2-1.4-1.2-1.2
Total zone transitions, hab. session 10.30.50.80.1-0.90.70.8-0.80.70.70.80.80.90.70.8-0.20.30.80.4-0.50.80.50.80.70.60.80.9
Total locomotion distance, hab. session 10.10.10.7-0.90.7-0.1-0.20.00.0-0.1-0.2-0.1-0.2-0.1-0.0-0.60.4-0.00.6-0.6-0.1-0.2-0.00.1-0.2-0.1-0.0
Locomotion velocity, hab. session 10.30.41.0-0.70.20.50.5-0.60.60.50.50.60.50.50.6-0.90.80.61.0-1.00.60.40.60.60.40.50.7
Time in familiar zone, hab. session 20.80.81.31.0-0.2-0.9-0.80.9-0.9-0.8-0.7-0.9-0.7-0.7-1.01.1-1.1-1.0-1.01.0-0.8-0.8-0.9-1.0-0.8-1.0-0.9
Time in novel zone, hab. session 20.80.81.3-1.10.30.90.8-0.91.00.80.70.90.80.81.0-1.01.01.00.9-0.90.90.80.91.00.81.00.9
Total zone transitions, hab. session 21.11.41.8-1.20.11.31.2-1.31.31.31.31.31.21.31.3-0.60.81.30.9-0.91.31.11.21.31.11.31.2
Total locomotion distance, hab. session 20.20.21.3-1.10.60.40.2-0.40.40.40.30.30.20.40.3-0.60.60.40.7-0.70.30.10.30.40.10.30.2
Locomotion velocity, hab. session 20.10.21.5-1.20.80.30.0-0.20.30.20.10.20.00.20.2-0.50.50.30.6-0.60.1-0.10.20.3-0.10.10.1
Novel to familiar place preference ratio2.12.23.2-1.0-0.41.71.7-1.61.61.51.41.61.41.41.7-1.31.31.81.2-1.11.61.41.71.61.41.61.6
Novelty place preference1.31.32.0-0.9-0.41.31.3-1.31.21.11.11.21.11.11.3-1.11.11.40.9-0.91.21.01.31.31.01.21.3
Time in novel zone, NPP test1.51.52.2-1.0-0.41.41.3-1.41.31.21.11.31.21.11.4-1.31.31.51.2-1.21.31.11.31.41.11.31.3
Total zone transitions, NPP test1.31.92.5-0.5-0.81.51.5-1.51.51.41.51.61.61.41.6-0.70.91.51.0-1.11.61.31.51.41.31.61.5
Total locomotion distance, NPP test0.10.20.5-0.7-0.10.60.4-0.50.50.40.40.50.50.40.6-0.00.20.60.2-0.30.50.20.50.50.30.50.5
Locomotion velocity, NPP test0.10.10.3-0.3-0.30.50.4-0.40.40.30.30.40.40.30.50.4-0.20.5-0.10.10.40.10.40.40.20.40.4
Pavlov. Cond. lever latency0.81.01.61.2-1.1-1.1-1.01.0-1.0-1.2-1.1-1.1-0.7-1.2-0.90.6-0.7-1.0-0.60.6-0.9-1.2-1.1-1.1-1.2-1.1-0.9
Pavlov. Cond. magazine entry latency0.81.12.0-1.11.40.90.9-0.90.91.21.00.90.61.20.6-1.31.30.61.2-1.20.71.21.01.01.20.90.9
Pavlov. Cond. change in total contacts0.20.21.2-0.31.10.40.3-0.30.30.70.60.40.20.70.1-0.50.50.10.5-0.50.30.70.40.40.70.40.4
Pavlov. Cond. index score0.30.40.8-0.40.90.70.6-0.60.60.90.80.70.50.90.4-0.60.60.40.6-0.50.50.90.70.70.90.60.6
Pavlov. Cond. latency score0.30.31.2-0.71.10.60.5-0.50.50.80.70.60.30.80.3-0.30.40.40.3-0.30.40.80.60.60.80.50.5
Pavlov. Cond. lever contacts0.10.21.0-0.71.00.40.3-0.30.30.50.40.30.10.50.20.00.10.2-0.00.10.20.50.40.40.50.40.3
Pavlov. Cond. magazine entry number0.50.61.2-0.2-0.5-0.7-0.80.7-0.7-1.1-1.1-0.8-0.7-1.0-0.40.9-0.8-0.4-0.90.9-0.7-1.0-0.8-0.7-1.0-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.80.9-0.70.20.3-0.20.10.20.40.20.40.20.20.5-0.30.2-0.30.30.20.20.20.10.20.20.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.0-0.40.70.80.8-0.70.71.01.00.80.71.00.5-0.70.80.60.7-0.70.71.00.80.81.00.80.8
Pavlov. Cond. response bias0.50.61.0-0.30.90.70.7-0.70.71.00.90.70.61.00.4-0.90.90.50.9-0.80.61.00.80.71.00.70.7
Bone: apparent density0.10.21.2-1.11.10.40.4-0.30.40.50.30.40.10.40.4-0.30.30.40.2-0.20.20.70.40.50.70.50.3
Bone surface1.12.03.3-1.51.61.51.4-1.41.41.71.41.50.91.61.3-1.11.11.30.9-0.91.21.81.51.61.81.61.4
Bone volume0.40.72.8-1.21.70.70.7-0.60.71.00.70.70.30.90.5-0.60.60.50.4-0.40.51.20.80.81.20.80.6
Bone: connectivity density1.21.92.5-1.61.01.41.4-1.41.51.51.31.51.11.51.4-1.21.31.41.1-1.11.31.61.51.61.61.51.3
Bone: cortical apparent density0.50.61.00.6-0.70.80.9-0.80.70.81.00.91.00.80.8-0.50.60.70.6-0.60.90.90.80.70.90.90.9
Bone: cortical area0.50.81.5-0.50.91.00.9-0.90.91.21.10.90.71.20.7-0.60.70.80.5-0.50.81.20.90.91.20.90.8
Bone: cortical porosity0.10.11.20.9-1.10.00.2-0.10.0-0.00.20.10.30.10.00.2-0.20.1-0.10.00.2-0.00.0-0.1-0.00.00.1
Bone: cortical porosity0.30.32.11.0-1.50.40.5-0.50.40.30.50.50.70.30.50.00.00.50.2-0.20.60.40.40.30.40.50.5
Bone: cortical thickness2.64.26.60.6-1.42.32.4-2.22.12.42.62.32.52.42.1-0.91.32.21.2-1.22.32.32.22.02.32.22.2
Bone: cortical thickness0.40.40.90.6-0.90.80.8-0.70.60.70.90.70.90.70.6-0.00.20.70.1-0.10.80.70.60.50.70.70.6
Bone: cortical tissue density0.60.81.30.7-0.90.91.0-0.90.90.91.11.01.10.90.9-0.60.70.80.7-0.71.01.10.90.81.01.01.0
Bone: elastic displacement0.60.71.81.3-1.3-0.7-0.60.6-0.7-0.8-0.6-0.6-0.3-0.9-0.41.3-1.2-0.6-1.00.9-0.5-0.6-0.7-0.8-0.7-0.6-0.6
Bone: elastic work0.70.92.10.4-1.41.11.1-1.11.00.91.11.01.30.81.1-0.10.21.20.4-0.41.21.00.90.91.01.01.0
Bone: endosteal estimation1.42.98.4-1.92.9-1.7-1.91.7-1.6-1.6-2.1-1.8-2.3-1.7-1.80.4-0.7-1.7-1.01.0-2.0-1.6-1.6-1.4-1.6-1.7-1.9
Bone: endosteal perimeter2.14.411.8-1.73.4-2.1-2.32.2-2.0-1.9-2.4-2.3-2.8-2.0-2.30.5-0.9-2.2-1.11.2-2.5-1.9-2.0-1.8-1.9-2.2-2.3
Bone: final force1.52.43.5-1.30.81.71.5-1.61.61.81.71.61.41.71.4-1.41.41.51.4-1.31.51.91.61.71.91.61.4
Bone: final moment1.42.23.3-1.20.81.71.5-1.51.61.81.61.61.31.71.4-1.31.41.51.3-1.31.41.81.51.61.81.61.4
Bone: marrow area1.53.38.1-1.92.8-1.8-2.01.8-1.7-1.7-2.2-1.9-2.4-1.8-1.90.6-0.9-1.8-1.11.1-2.1-1.7-1.7-1.5-1.7-1.8-2.0
Bone: maximum diameter0.10.32.4-0.91.50.30.2-0.20.30.50.30.2-0.10.50.0-0.60.60.20.4-0.30.10.50.30.40.50.20.1
Bone: maximum force2.03.55.3-2.31.91.91.7-1.81.92.11.71.81.32.01.6-1.91.91.71.7-1.71.62.21.92.02.21.91.7
Bone: maximum moment1.83.24.6-2.21.81.81.7-1.71.82.11.71.71.21.91.6-1.81.81.61.6-1.61.52.11.81.92.11.81.6
Bone: minimum diameter0.91.78.4-1.72.9-1.2-1.41.3-1.1-1.0-1.4-1.3-1.8-1.0-1.30.2-0.4-1.3-0.60.7-1.5-1.0-1.1-0.9-1.0-1.2-1.3
Bone: periosteal estimation0.20.55.7-1.62.4-0.3-0.50.5-0.4-0.1-0.5-0.5-0.9-0.2-0.6-0.30.2-0.5-0.10.2-0.7-0.2-0.3-0.2-0.2-0.4-0.6
Bone: periosteal perimeter0.20.33.3-0.81.8-0.2-0.40.3-0.30.0-0.3-0.3-0.6-0.1-0.6-0.20.1-0.4-0.00.1-0.5-0.1-0.2-0.1-0.1-0.4-0.4
Bone: post-yield work0.91.212.3-2.43.5-0.7-0.80.8-0.6-0.4-0.9-0.7-1.5-0.4-0.9-0.30.1-0.9-0.20.3-1.1-0.4-0.5-0.3-0.4-0.6-0.8
Bone: stiffness0.40.71.6-0.91.20.80.7-0.70.81.10.90.70.51.00.5-0.90.90.60.7-0.60.61.00.80.81.00.70.6
Bone: tissue strength0.60.60.70.20.3-0.7-0.80.8-0.8-0.7-0.7-0.8-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.8-0.7-0.8-0.8-0.7-0.8-0.8
Bone: trabecular number0.50.81.7-1.31.10.80.8-0.80.90.90.70.80.50.90.8-1.01.00.80.8-0.80.71.10.91.01.10.90.7
Bone: trabecular spacing0.30.41.51.2-1.0-0.6-0.60.5-0.5-0.5-0.3-0.5-0.1-0.6-0.60.7-0.6-0.6-0.40.4-0.4-0.6-0.7-0.7-0.6-0.6-0.6
Bone: trabecular thickness0.40.50.9-0.11.0-0.8-0.70.8-0.8-0.6-0.7-0.8-0.9-0.6-0.90.6-0.7-0.9-0.70.8-0.9-0.5-0.7-0.7-0.5-0.8-0.7
Bone: trabecular tissue density3.65.06.11.4-0.2-2.3-2.22.4-2.4-2.4-2.2-2.4-2.2-2.3-2.32.2-2.2-2.3-2.22.2-2.3-2.5-2.3-2.4-2.5-2.4-2.2
Breakpoint value in progressive ratio session2.22.53.70.4-1.31.51.7-1.61.51.81.91.61.91.71.4-1.51.51.31.6-1.61.71.71.61.41.71.51.7
Distance traveled before self-admin1.82.03.3-0.30.31.41.4-1.31.41.71.61.51.41.71.2-1.41.51.01.4-1.41.31.81.41.41.81.51.4
Distance traveled after self-admin0.10.20.40.10.30.20.4-0.30.40.60.50.40.40.60.3-0.40.50.10.4-0.40.30.60.40.40.60.30.4
Delta time in closed arm before/after self-admin2.52.44.3-1.3-1.61.51.6-1.81.81.31.31.71.81.32.1-1.21.21.81.4-1.41.81.21.61.61.21.81.6
Delta time in open arm before/after self-admin1.41.32.20.10.21.11.1-1.01.01.41.51.11.21.30.7-1.51.50.81.4-1.41.01.31.11.01.30.91.2
Diff in mean of infusions in LGA sessions1.82.13.20.5-1.61.51.6-1.51.41.51.71.51.81.41.3-1.11.21.41.2-1.21.61.51.41.31.51.51.6
Extinction: sum of active levers before priming3.43.44.4-0.7-0.41.82.0-1.91.92.12.01.91.92.01.7-1.91.91.71.9-1.91.92.02.01.92.01.92.0
Active lever presses in extinction session 62.22.13.80.3-0.61.41.6-1.41.41.81.91.51.71.71.1-1.41.31.11.4-1.41.51.81.51.31.81.41.6
Delta distance traveled before/after self-admin0.70.81.20.4-0.3-0.9-0.90.9-0.9-1.0-1.0-1.0-0.8-1.1-0.80.9-0.9-0.7-0.90.9-0.8-1.1-0.9-0.9-1.1-1.1-0.9
Delta ambulatory time before/after self-admin1.01.11.50.5-0.7-1.1-1.01.0-1.0-1.2-1.1-1.0-0.9-1.2-0.91.2-1.1-0.8-1.11.1-0.9-1.2-1.1-1.0-1.2-1.0-1.0
Time in closed arm before self-admin0.10.11.30.01.2-0.3-0.20.3-0.30.0-0.1-0.2-0.40.0-0.50.00.0-0.5-0.20.2-0.40.1-0.2-0.20.1-0.3-0.2
Time in closed arm after self-admin0.20.20.5-0.2-0.2-0.7-0.50.4-0.4-0.7-0.7-0.4-0.5-0.6-0.30.5-0.5-0.5-0.50.5-0.4-0.5-0.5-0.4-0.5-0.4-0.4
Time in open arm before self-admin1.01.02.70.3-1.5-0.7-0.80.7-0.7-1.2-1.1-0.8-0.6-1.2-0.31.6-1.5-0.3-1.41.4-0.6-1.3-0.9-0.8-1.3-0.7-0.9
Time in open arm after self-admin0.20.22.11.1-1.40.30.2-0.10.00.10.30.00.4-0.1-0.00.4-0.20.1-0.20.20.2-0.10.0-0.1-0.10.00.2
Sum of active levers in priming session hrs 5-60.80.81.70.7-0.40.80.9-0.80.71.11.30.91.01.20.5-0.80.80.40.8-0.80.81.20.80.71.20.80.9
Time to tail flick, vehicle, before self-admin0.70.72.3-1.51.30.70.6-0.70.80.70.40.60.30.70.7-1.21.10.81.0-1.00.60.50.80.90.50.60.7
Time to tail flick, vehicle, after self-admin0.70.71.3-1.10.20.70.7-0.90.90.80.60.90.70.81.0-0.90.90.90.9-0.90.80.90.80.90.91.00.7
Time to tail flick, test, before self-admin0.20.21.3-1.10.50.60.4-0.40.50.0-0.10.40.00.10.6-0.30.41.00.3-0.20.30.20.50.60.20.50.4
Time to tail flick, test, after self-admin0.20.20.80.9-0.4-0.3-0.30.4-0.4-0.5-0.3-0.3-0.3-0.4-0.30.7-0.6-0.2-0.60.6-0.3-0.3-0.4-0.4-0.3-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.10.00.20.1-0.50.10.2-0.20.20.20.20.20.30.20.30.2-0.20.1-0.10.10.20.40.10.10.30.30.1
Delta time to tail flick, test, before/after SA0.20.22.51.6-1.2-0.2-0.00.1-0.20.10.4-0.00.40.1-0.30.2-0.3-0.5-0.10.00.00.1-0.2-0.30.1-0.1-0.0
Ambulatory time before self-admin1.51.62.8-0.00.51.21.2-1.11.11.61.61.31.21.60.9-1.31.30.91.3-1.21.11.71.31.21.71.21.2
Ambulatory time after self-admin0.20.22.2-0.41.50.10.2-0.20.30.50.30.3-0.00.60.0-0.60.7-0.10.5-0.40.10.60.30.40.60.30.2
Total heroin consumption3.74.46.80.4-2.22.22.3-2.22.12.22.52.22.62.22.1-1.51.72.11.8-1.82.42.22.21.92.22.12.4
Area under the delay curve0.10.10.6-0.80.60.20.3-0.30.30.2-0.00.3-0.10.20.50.2-0.10.4-0.20.20.20.20.40.40.20.30.3
Delay disc. indifference point, 0s delay0.20.21.6-1.31.1-0.2-0.30.10.0-0.2-0.7-0.2-0.5-0.30.20.0-0.00.1-0.10.1-0.2-0.4-0.10.1-0.4-0.0-0.3
Delay disc. indifference point, 16s delay0.10.10.8-0.60.90.20.2-0.20.30.40.20.20.00.30.2-0.40.40.20.3-0.30.10.40.30.30.40.30.3
Delay disc. indifference point, 2s delay0.30.32.6-0.81.6-0.4-0.40.4-0.3-0.3-0.6-0.3-0.8-0.3-0.30.4-0.4-0.3-0.50.6-0.5-0.3-0.2-0.1-0.3-0.3-0.4
Delay disc. indifference point, 24s delay0.10.10.3-0.40.00.40.3-0.30.30.10.10.30.20.20.50.2-0.10.5-0.20.20.30.20.30.40.20.40.3
Delay disc. indifference point, 4s delay0.50.51.5-1.20.20.80.8-0.80.80.50.30.70.40.41.10.10.11.2-0.00.10.70.50.80.90.50.80.8
Delay disc. indifference point, 8s delay0.20.20.8-0.0-0.4-0.3-0.10.3-0.3-0.5-0.6-0.3-0.4-0.60.10.9-0.8-0.0-0.80.9-0.3-0.6-0.2-0.2-0.6-0.2-0.1
Delay discount exponential model param0.10.10.60.8-0.6-0.2-0.30.2-0.3-0.20.1-0.20.1-0.1-0.5-0.20.1-0.40.2-0.3-0.2-0.2-0.3-0.4-0.2-0.3-0.3
Delay discount hyperbolic model param0.10.10.80.9-0.7-0.3-0.30.3-0.3-0.20.1-0.30.1-0.2-0.5-0.20.1-0.50.2-0.3-0.2-0.2-0.4-0.4-0.2-0.4-0.3
Fecal boli incidents, locomotor time 10.30.30.90.50.7-0.7-0.70.6-0.6-0.4-0.4-0.6-0.5-0.3-0.9-0.40.2-0.90.3-0.3-0.7-0.3-0.6-0.6-0.3-0.7-0.6
Change in fecal boli incidents, locomotor task0.70.71.7-0.80.2-0.5-0.70.5-0.5-0.9-1.1-0.7-0.9-1.1-0.21.3-1.2-0.2-1.31.3-0.6-0.9-0.7-0.5-1.0-0.5-0.9
Time >=10cm from walls, locomotor time 12.12.13.3-0.01.8-1.7-1.71.7-1.6-1.3-1.6-1.7-1.8-1.4-1.80.1-0.4-1.8-0.40.4-1.8-1.4-1.5-1.5-1.4-1.7-1.6
Bouts of movement, locomotor time 10.60.74.51.7-2.10.40.7-0.50.40.61.10.61.20.60.3-0.60.50.30.7-0.80.70.70.50.20.70.50.8
Total resting periods, locomotor time 10.50.52.11.4-1.50.40.7-0.50.40.71.00.61.00.70.3-0.60.50.20.6-0.70.60.70.50.30.70.50.7
Rest time, locomotor task time 11.21.31.71.0-0.4-1.3-1.11.2-1.3-0.9-1.2-1.3-1.1-1.3-1.10.9-1.0-1.3-0.90.9-1.2-1.3-1.2-1.3-1.3-1.3-1.0
Distance moved, locomotor task time 10.30.30.8-0.90.70.50.4-0.50.60.30.40.50.30.60.4-0.70.60.50.6-0.60.40.60.50.60.60.50.3
Vertical activity count, locomotor time 10.70.71.20.10.2-0.8-0.90.8-0.8-1.1-0.9-0.8-0.8-0.9-0.91.0-1.0-0.8-1.01.0-0.8-0.8-0.9-0.8-0.8-0.8-0.9
Time >=10cm from walls, locomotor time 20.30.30.80.90.3-0.5-0.50.6-0.6-0.6-0.3-0.5-0.5-0.3-0.80.3-0.3-0.7-0.40.4-0.6-0.3-0.6-0.6-0.3-0.7-0.5
Bouts of movement, locomotor time 22.02.15.70.2-1.01.21.1-1.31.31.61.51.31.61.31.1-2.22.01.12.3-2.41.41.21.21.11.21.11.3
Total resting periods, locomotor time 21.31.45.00.2-0.90.80.7-0.91.01.21.10.91.30.90.8-2.01.80.72.2-2.21.00.80.80.80.80.70.9
Rest time, locomotor task time 22.32.74.30.6-0.2-1.9-1.91.8-1.8-1.7-2.0-1.9-1.7-2.1-1.70.8-1.1-1.8-0.80.8-1.8-2.1-1.8-1.8-2.1-1.9-1.7
Distance moved, locomotor task time 20.30.40.90.6-0.40.70.8-0.60.60.60.90.70.70.90.50.10.10.5-0.10.10.70.80.60.60.80.60.6
Vertical activity count, locomotor time 20.40.42.41.1-1.60.00.10.1-0.2-0.40.0-0.10.2-0.2-0.11.3-1.10.1-1.11.10.0-0.2-0.2-0.3-0.2-0.1-0.1
Weight adjusted by age2.42.76.8-0.90.11.31.2-1.51.51.61.51.51.51.61.2-2.62.31.32.6-2.61.51.61.41.51.61.41.3
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.50.40.00.0-0.10.1-0.1-0.10.0-0.1-0.00.1-0.30.30.00.2-0.20.0-0.10.10.1-0.10.00.1
Locomotion in novel chamber2.02.53.9-0.12.0-1.8-1.71.8-1.7-1.5-1.7-1.7-2.0-1.4-1.91.0-1.2-1.8-1.21.3-1.9-1.5-1.6-1.5-1.5-1.8-1.7
Locomotion in novel chamber post-restriction1.82.12.71.2-0.8-1.5-1.41.5-1.5-1.6-1.5-1.5-1.2-1.6-1.41.4-1.5-1.4-1.31.3-1.4-1.6-1.5-1.6-1.6-1.6-1.4
Progressive ratio0.10.10.8-0.50.9-0.2-0.20.2-0.1-0.0-0.1-0.1-0.30.0-0.3-0.40.3-0.40.3-0.3-0.20.1-0.1-0.00.1-0.0-0.1
Food seeking constrained by brief footshock0.10.10.40.0-0.4-0.3-0.30.2-0.2-0.3-0.3-0.2-0.2-0.4-0.10.6-0.5-0.2-0.50.5-0.2-0.3-0.3-0.3-0.3-0.2-0.4
Seeking ratio, punishment vs. effort0.10.11.10.2-1.10.10.0-0.10.1-0.2-0.20.00.2-0.30.30.7-0.50.4-0.50.40.2-0.4-0.1-0.0-0.4-0.1-0.1
Run reversals in cocaine runway, females0.70.72.6-1.60.71.00.8-0.90.90.60.40.80.40.61.1-0.70.81.20.6-0.60.70.70.91.00.70.90.7
Run reversals in cocaine runway, males1.00.92.90.6-0.3-0.7-0.60.8-0.9-0.8-0.7-0.8-0.8-0.8-0.61.7-1.5-0.6-1.71.7-0.8-1.0-0.7-0.8-1.0-0.9-0.6
Latency to leave start box in cocaine runway0.50.63.4-1.31.8-0.5-0.60.6-0.6-0.6-0.8-0.6-1.1-0.5-0.60.4-0.4-0.5-0.70.7-0.8-0.5-0.5-0.4-0.5-0.6-0.7
Latency to leave start box in cocaine runway, F0.10.11.2-0.91.10.10.1-0.10.10.2-0.00.1-0.20.20.1-0.10.20.10.00.00.00.20.20.30.20.20.1
Latency to leave start box in cocaine runway, M3.43.34.30.00.9-1.9-1.81.9-1.9-1.9-1.9-1.9-2.1-1.9-1.81.7-1.8-1.8-2.02.0-2.0-1.8-1.9-1.8-1.8-1.8-1.9
Cd content in liver1.11.21.70.50.6-1.1-1.21.2-1.2-1.0-1.0-1.1-1.1-0.9-1.31.3-1.3-1.2-1.21.2-1.2-1.0-1.2-1.1-1.0-1.2-1.2
Co content in liver2.02.34.22.1-1.4-1.5-1.41.4-1.5-1.5-1.2-1.4-1.0-1.5-1.41.9-1.9-1.5-1.71.6-1.3-1.5-1.6-1.7-1.5-1.5-1.5
Cu content in liver0.30.31.00.1-1.00.60.6-0.70.60.30.50.60.70.40.9-0.10.20.80.2-0.20.70.40.50.60.40.70.5
Fe content in liver0.00.00.2-0.1-0.00.1-0.0-0.10.1-0.00.00.00.10.00.1-0.40.30.10.4-0.40.10.00.00.10.00.0-0.0
K content in liver0.90.91.9-1.41.30.90.9-0.80.90.90.70.90.51.00.9-1.11.10.80.9-0.90.71.01.01.11.00.90.9
Mg content in liver0.50.53.0-1.71.60.50.3-0.50.60.50.30.50.10.60.5-0.70.70.50.6-0.60.30.50.50.70.50.50.4
Mn content in liver1.51.82.4-0.60.11.51.5-1.41.41.41.41.41.21.51.4-1.21.21.41.2-1.11.41.41.51.51.41.41.5
Na content in liver0.40.40.8-0.50.70.60.6-0.60.60.90.80.70.50.90.5-0.40.60.50.5-0.50.60.90.70.70.90.70.6
Rb content in liver1.41.82.4-0.30.7-1.4-1.51.4-1.3-1.5-1.6-1.4-1.5-1.5-1.31.1-1.2-1.3-1.21.2-1.4-1.5-1.4-1.3-1.5-1.4-1.5
Se content in liver0.40.41.3-0.50.40.50.6-0.50.60.60.50.50.40.60.5-1.21.00.41.0-1.00.50.60.60.60.60.50.6
Sr content in liver6.66.17.5-0.3-1.12.52.6-2.62.62.62.62.62.72.62.6-2.22.42.52.5-2.52.72.62.62.52.62.62.6
Zn content in liver4.44.95.8-0.9-0.02.22.2-2.32.32.32.42.32.32.42.2-2.32.32.12.4-2.42.32.42.32.32.42.32.3