Hub : Genes

Zc2hc1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000022356 0.47 0.13 0.0e+00 0.33 0.34 0.35 0.34 1.1e-37 2.9e-39 2.9e-40 2.0e-39
2 Adipose mRNA stability ENSRNOG00000022356 0.13 0.06 6.2e-14 0.1 0.1 0.1 0.1 2.6e-11 1.3e-11 3.4e-11 1.6e-11
3 Brain gene expression ENSRNOG00000022356 0.04 0.02 3.0e-03 0 0.02 0.01 0.01 1.4e-01 5.6e-03 8.7e-02 4.8e-02
4 IL alternative polyA ENSRNOT00000095126 0.29 0.14 9.6e-03 0.01 0.01 -0.01 -0.01 2.1e-01 1.9e-01 4.8e-01 6.1e-01
5 IL alternative polyA ENSRNOT00000109624 0.32 0.15 6.1e-03 -0.01 0.02 -0.01 -0.01 5.5e-01 1.3e-01 7.7e-01 4.9e-01
6 IL alternative polyA ENSRNOT00000095126 0.34 0.15 3.2e-03 0.01 0.02 -0.01 0.01 2.2e-01 9.7e-02 5.1e-01 2.2e-01
7 IL alternative polyA ENSRNOT00000109624 0.3 0.14 6.8e-03 -0.01 0.01 -0.01 -0 5.7e-01 1.9e-01 6.6e-01 3.9e-01
8 LHb alternative TSS ENSRNOT00000090866 0.3 0.14 2.3e-03 0.01 0.04 0.05 0.01 1.8e-01 4.4e-02 2.3e-02 1.4e-01
9 NAcc gene expression ENSRNOG00000022356 0.03 0.02 7.9e-03 0.03 0.02 0.01 0.03 2.5e-03 1.1e-02 5.6e-02 3.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.75.610.42.42.53.2-2.52.1-2.52.50.52.0
BMI without tail4.79.720.53.94.04.5-2.31.6-2.22.22.63.6
Body weight1.35.49.31.82.13.1-2.82.5-2.82.80.61.3
Epididymis fat weight0.20.51.2-1.0-1.1-0.9-0.20.2-0.10.10.5-0.9
Glucose0.30.51.20.70.70.8-0.60.4-0.50.51.10.7
Heart weight0.81.12.0-0.9-1.1-1.30.8-0.81.0-1.01.4-1.0
Left kidney weight0.30.73.01.00.80.50.5-0.70.6-0.71.70.4
Right kidney weight0.20.72.80.50.40.00.6-0.90.8-0.91.70.1
Tail length0.61.93.91.51.62.0-0.90.7-0.90.91.61.6
Length with tail0.20.81.7-0.2-0.00.6-1.31.3-1.31.30.1-0.3
Length without tail1.02.35.4-2.1-1.9-1.7-0.10.5-0.20.3-2.3-2.0
Liver weight, left1.01.63.20.10.21.0-1.81.7-1.71.71.30.1
Liver weight, right0.20.32.40.40.20.4-0.20.1-0.10.11.50.3
Parametrial fat weight0.10.10.50.40.40.4-0.0-0.0-0.0-0.00.70.1
Retroperitoneal fat weight0.62.15.5-2.1-2.1-1.7-0.70.8-0.50.6-0.4-2.3
Intraocular pressure3.95.511.1-1.5-1.40.3-3.33.2-3.13.01.9-1.1
Extensor digitorum longus weight4.417.833.22.02.34.5-5.85.0-5.45.43.02.2
Soleus weight0.61.83.61.61.71.9-1.00.7-0.90.91.31.6
Tibialis anterior weight5.017.333.91.62.04.2-5.85.3-5.75.71.61.6
Tibia length0.92.64.71.21.2-0.02.2-2.11.9-1.9-1.80.8
Number of licking bursts0.00.10.10.2-0.00.1-0.30.3-0.30.30.4-0.0
Food consumed during 24 hour testing period0.40.51.30.70.60.7-0.80.5-0.60.61.10.6
Times rat made contact with spout0.10.10.20.40.50.4-0.20.1-0.20.2-0.30.5
Mean time between licks in bursts1.21.63.2-1.6-1.6-1.2-0.70.9-0.70.8-1.7-1.8
Mean num. licks in bursts0.10.10.30.00.30.10.2-0.30.2-0.2-0.50.3
Std. dev. time between licks in bursts1.21.42.8-1.7-1.6-1.70.5-0.20.4-0.4-1.1-1.6
Water consumed over 24 hours0.10.10.40.50.60.40.0-0.20.1-0.0-0.40.5
Indifference point 0 sec0.20.40.80.90.90.80.5-0.40.4-0.40.60.2
Indifference point AUC1.11.33.1-0.4-0.50.4-1.51.4-1.31.31.8-0.5
Indifference point function ln k0.60.91.61.31.20.70.8-1.00.8-0.80.41.1
Indifference point function log k0.60.91.61.31.20.70.8-1.00.8-0.80.41.1
Delay discounting total patch changes 0 sec0.30.51.21.01.00.90.3-0.30.2-0.31.10.4
Delay discounting total patch changes 12 sec0.30.41.70.70.70.8-0.10.1-0.10.11.30.3
Delay discounting total patch changes 18 sec0.40.61.20.70.71.1-0.70.7-0.70.61.10.3
Delay discounting total patch changes 24 sec0.50.72.00.60.61.0-0.60.6-0.60.51.41.0
Delay discounting total patch changes 6 sec0.50.71.70.80.81.2-0.70.7-0.70.71.30.4
Delay discounting time to switch 0 sec0.71.13.2-0.9-0.6-0.2-1.11.2-1.11.2-1.8-0.4
Delay discounting water rate 0 sec0.91.42.11.41.20.71.1-1.21.1-1.11.31.3
Delay discounting water rate 12 sec1.31.92.91.71.70.71.6-1.61.5-1.4-0.81.1
Delay discounting water rate 18 sec1.52.03.21.31.40.51.8-1.71.5-1.5-1.31.5
Delay discounting water rate 24 sec1.52.13.31.51.50.71.6-1.61.5-1.50.81.8
Delay discounting water rate 6 sec0.50.71.30.20.1-0.41.1-1.11.1-1.20.70.6
Locomotor activity1.52.34.60.60.61.4-2.11.8-1.91.91.60.6
Locomotor testing distance0.91.52.60.70.71.3-1.61.3-1.51.51.21.0
Locomotor testing rearing0.50.71.41.11.10.70.5-0.70.6-0.60.91.2
Light reinforcement 10.00.00.1-0.1-0.1-0.1-0.20.1-0.10.10.3-0.2
Light reinforcement 20.50.61.30.20.30.7-1.11.0-1.11.1-0.40.2
Reaction time number correct0.20.30.40.60.60.40.5-0.40.4-0.4-0.50.6
Reaction time mean minus median1.52.06.9-0.8-0.9-0.1-1.81.4-1.41.32.6-0.8
Reaction time mean minus median AUC1.62.04.5-0.7-0.70.2-2.01.6-1.61.62.1-0.7
Reaction time num false alarms0.50.62.1-0.7-0.7-0.3-0.40.7-0.60.6-1.4-1.1
Reaction time num false alarms AUC0.40.61.8-0.9-0.8-0.6-0.10.5-0.30.3-1.3-1.1
Reaction time trials correct on left0.20.30.40.60.60.40.5-0.40.4-0.4-0.50.6
Reaction time trials on left0.10.20.30.60.60.40.4-0.30.2-0.3-0.50.5
Reaction time mean1.31.73.4-1.0-1.0-0.1-1.91.7-1.71.71.0-0.8
Reaction time mean AUC1.21.63.2-1.1-1.1-0.2-1.81.7-1.61.60.9-0.8
Median of all reaction times0.91.22.4-0.9-0.80.0-1.51.6-1.51.50.2-0.6
Reaction time omissions0.91.22.0-1.0-1.1-0.4-1.41.3-1.21.11.4-0.3
Reaction time false alarm rate0.20.31.0-0.7-0.6-0.4-0.20.4-0.30.3-0.8-1.0
Reaction time premature initiation rate1.41.93.01.21.20.51.5-1.61.5-1.51.21.7
Reaction time premature initiations1.52.13.41.51.40.71.5-1.61.5-1.51.11.8
Std. dev. reaction times1.72.46.3-1.0-1.1-0.1-2.01.7-1.61.62.5-0.9
Reaction time trials completed0.10.20.30.60.60.40.4-0.30.2-0.3-0.50.5
Reaction time trials AUC0.10.10.50.40.40.20.3-0.20.2-0.2-0.70.3
Social response proportion0.60.71.8-0.8-1.0-1.30.6-0.80.8-0.80.1-0.6
Social responses0.60.83.60.60.30.00.6-0.90.8-0.81.90.5
Social time0.50.71.1-0.3-0.5-0.81.0-0.91.0-1.10.6-0.7
Conditioned locomotion1.01.12.6-1.5-1.5-1.4-0.20.3-0.10.2-1.1-1.6
Cocaine response after cond. corrected0.20.20.4-0.00.1-0.20.7-0.60.6-0.6-0.5-0.0
Cocaine response after cond. not corrected1.01.22.0-1.0-1.0-1.41.1-0.91.0-1.0-1.0-1.1
Cocaine response before conditioning1.62.04.9-2.1-2.2-2.00.00.20.1-0.1-0.7-2.1
Saline control response1.21.62.7-1.7-1.5-0.7-1.21.4-1.21.2-0.2-1.6
Condit. Reinf. active minus inactive responses2.93.67.0-2.6-2.5-2.1-0.61.0-0.70.7-2.4-2.6
Condit. Reinf. active-inactive response ratio2.02.15.6-1.6-1.5-1.1-0.91.1-1.01.1-2.4-1.7
Condit. Reinf. active responses3.04.18.4-2.9-2.8-2.3-0.51.0-0.60.6-2.3-2.9
Condit. Reinf. inactive responses0.40.51.4-1.2-1.1-0.80.00.2-0.10.0-0.5-1.0
Condit. Reinf. lever presses0.30.41.4-0.7-0.6-0.4-0.30.5-0.40.4-1.2-0.8
Condit. Reinf. lever reinforcers received2.63.77.6-2.7-2.7-2.1-0.51.0-0.60.6-2.1-2.8
Pavlov. Cond. lever latency0.10.10.60.30.40.4-0.1-0.0-0.00.00.80.5
Pavlov. Cond. magazine entry latency0.60.71.5-0.10.00.5-1.11.2-1.21.2-0.7-0.2
Pavlov. Cond. change in total contacts1.01.42.8-0.6-0.50.1-1.31.5-1.51.5-1.7-0.7
Pavlov. Cond. index score0.40.61.6-0.2-0.20.2-0.81.0-0.91.0-1.2-0.4
Pavlov. Cond. latency score0.30.41.3-0.2-0.10.2-0.60.8-0.80.8-1.1-0.3
Pavlov. Cond. lever contacts0.10.21.3-0.3-0.3-0.40.2-0.10.1-0.1-1.1-0.5
Pavlov. Cond. magazine entry number0.70.81.6-0.1-0.2-0.71.1-1.21.3-1.30.90.0
Pavlov. Cond. intertrial magazine entries0.20.21.00.30.20.4-0.40.3-0.30.31.00.3
Pavlov. Cond. lever-magazine prob. diff.0.40.51.5-0.3-0.20.1-0.60.8-0.80.8-1.2-0.4
Pavlov. Cond. response bias0.50.72.2-0.7-0.6-0.2-0.60.9-0.80.8-1.5-0.8
Conditioned reinforcement - actives1.41.43.30.10.2-0.51.8-1.61.6-1.6-0.90.3
Conditioned reinforcement - inactives0.80.91.50.70.90.31.2-1.11.0-1.0-1.00.8
Conditioned locomotion0.30.30.6-0.5-0.5-0.80.6-0.50.6-0.6-0.4-0.6
Intermittent access intake day 1-15 change1.61.63.7-1.7-1.8-1.90.6-0.50.7-0.7-0.4-1.6
Intermittent access intake escalation0.80.82.0-1.2-1.3-1.40.4-0.40.5-0.5-0.3-1.1
Intermittent access intake escalation 21.41.43.2-1.6-1.7-1.80.4-0.30.5-0.5-0.3-1.6
Intermitt. access day 1 inactive lever presses0.20.21.2-0.2-0.6-0.5-0.40.0-0.00.11.1-0.5
Intermitt. access day 15 inactive lever presses1.92.14.40.1-0.2-1.11.9-2.02.1-2.11.00.2
Intermitt. access escalation Index0.20.21.1-0.1-0.3-0.30.0-0.10.1-0.21.0-0.5
Intermittent access day 1 total infusions0.40.41.40.10.2-0.11.0-0.60.7-0.7-1.2-0.0
Intermittent access day 15 total infusions1.21.42.2-0.8-0.7-1.21.5-1.11.3-1.3-1.5-0.8
Intermittent access terminal intake (last 3 days)1.71.83.6-1.6-1.6-1.91.1-0.81.0-1.0-0.9-1.6
Intermittent access total infusions0.40.50.8-0.7-0.7-0.80.7-0.40.5-0.5-0.9-0.8
Intermittent access day 1 locomotion0.20.20.90.50.50.20.4-0.30.3-0.2-1.00.2
Intermittent access day 15 total locomotion0.80.82.80.40.5-0.21.1-1.01.0-0.9-1.70.2
Intermittent access total locomotion0.20.21.4-0.00.0-0.20.2-0.10.1-0.1-1.2-0.3
Intermittent access standard deviation0.91.02.5-1.5-1.6-1.3-0.10.20.0-0.10.6-1.3
Cocaine induced anxiety0.40.51.10.90.80.70.2-0.40.3-0.31.00.9
Post-drug Anxiety0.10.10.30.30.20.10.2-0.30.3-0.30.60.5
Baseline Anxiety0.90.91.8-1.3-1.2-1.30.8-0.50.7-0.7-1.0-0.9
Lifetime Intake0.50.50.9-0.6-0.5-0.70.9-0.60.7-0.8-0.9-0.7
Incentive Sensitization - Responses1.31.32.6-1.5-1.4-1.0-0.50.8-0.60.6-1.5-1.6
Incentive Sensitization - Breakpoint1.11.12.4-1.4-1.3-1.0-0.30.6-0.40.4-1.4-1.5
Progressive ratio test 1 active lever presses0.70.71.70.30.2-0.31.3-1.21.2-1.30.20.2
Progressive ratio test 1 breakpoint0.40.51.0-0.1-0.1-0.51.0-0.91.0-1.00.1-0.2
Progressive ratio test 1 inactive lever presses0.40.40.9-0.1-0.2-0.61.0-0.91.0-1.0-0.1-0.1
Progressive ratio test 2 active lever presses0.60.61.5-0.1-0.1-0.51.1-0.90.9-0.9-1.2-0.2
Progressive ratio test 2 breakpoint0.40.51.8-0.3-0.3-0.60.8-0.50.6-0.6-1.3-0.5
Progressive ratio test 2 inactive lever presses0.81.01.90.80.70.11.4-1.41.3-1.30.10.6
Total sessions with >9 infusions0.40.51.1-1.0-1.0-0.90.2-0.10.2-0.30.3-1.0
Short access day 1 total inactive lever presses0.80.91.9-0.1-0.2-0.81.4-1.31.3-1.3-0.4-0.2
Short access day 10 total inactive lever presses0.20.21.50.1-0.2-0.2-0.1-0.10.1-0.11.2-0.2
Short access day 1 total infusions0.70.71.5-1.1-1.1-1.20.5-0.40.5-0.5-0.3-1.2
Short access day 10 total infusions0.80.82.1-0.2-0.3-0.71.4-1.21.3-1.3-0.2-0.4
Short access total infusions0.91.01.4-0.8-0.8-1.11.2-0.81.0-1.0-1.0-0.9
Short access day 1 locomotion0.40.41.00.80.80.50.3-0.50.4-0.41.00.8
Short access day 10 total locomotion0.20.30.70.80.70.6-0.20.0-0.20.2-0.80.4
Short access total locomotion0.00.00.20.30.20.2-0.10.0-0.10.10.50.1
Compulsive drug intake3.02.94.91.31.52.2-2.01.8-2.02.1-0.01.5
One hour access (0.3 mA shock)0.50.61.31.01.10.90.6-0.40.4-0.4-0.31.1
One hour access (shock baseline)1.92.25.20.60.5-0.42.3-2.12.1-2.1-0.20.6
Number of responses in last shaping day0.30.31.9-0.1-0.4-0.1-0.60.3-0.30.31.4-0.3
Context. condit. distance diff. score0.30.42.2-0.4-0.5-0.1-0.70.5-0.50.41.50.0
Locomotion velocity, session 10.20.20.5-0.1-0.10.2-0.70.6-0.60.60.40.1
Locomotion distance, session 11.31.73.8-0.5-0.30.7-1.92.0-1.91.9-0.1-0.2
Locomotion velocity, session 22.42.85.70.40.41.5-2.42.3-2.42.30.90.2
Locomotion distance, session 21.92.75.8-0.8-0.60.6-2.22.4-2.32.3-0.8-0.8
Locomotion velocity, session 30.10.10.10.1-0.1-0.20.3-0.40.4-0.40.10.1
Locomotion distance, session 30.60.61.3-0.5-0.40.2-1.01.1-1.11.1-0.6-0.4
Stereotopy head waving bouts, day 30.30.40.90.10.1-0.40.9-0.90.9-0.9-0.10.4
Stereotopy head waving duration, day 31.01.22.11.41.30.90.7-0.90.8-0.81.21.4
Locomotion velocity, session 75.96.513.8-3.7-3.5-2.9-0.10.9-0.40.4-3.2-3.6
Locomotion distance, session 72.43.16.4-2.5-2.4-2.20.50.10.3-0.3-2.3-2.3
Stereotopy head waving bouts, day 70.50.61.3-0.2-0.10.4-1.11.1-1.11.10.20.1
Stereotopy head waving duration, day 70.80.91.71.01.11.3-0.70.5-0.70.71.11.2
Locomotion velocity, session 82.53.06.8-0.3-0.20.9-2.62.4-2.52.50.9-0.3
Locomotion distance, session 81.82.75.5-1.1-1.00.2-2.32.3-2.22.20.8-0.8
Degree of sensitization distance0.91.01.9-1.1-1.1-1.40.9-0.60.8-0.8-1.0-0.9
Degree of sensitization stereotypy1.92.04.20.20.31.1-2.11.8-1.91.91.40.4
Condit. Reinf. active minus inactive responses2.32.63.3-1.8-1.7-0.9-1.61.8-1.61.7-1.7-1.5
Condit. Reinf. active-inactive response ratio3.33.64.9-2.1-2.0-1.0-1.72.0-1.81.9-2.2-1.9
Condit. Reinf. active responses2.12.63.7-1.9-1.9-1.1-1.51.7-1.51.5-1.8-1.6
Condit. Reinf. inactive responses0.00.00.00.10.10.1-0.10.1-0.10.1-0.10.1
Incentive salience index mean2.02.54.7-1.3-1.2-0.2-2.02.2-2.02.1-1.1-0.9
Condit. Reinf. lever presses1.52.04.3-0.10.01.0-2.02.1-2.12.10.10.0
Time in familiar zone, hab. session 12.12.04.02.01.91.40.7-0.90.7-0.71.22.0
Time in novel zone, hab. session 11.91.94.2-2.0-2.0-1.8-0.10.3-0.00.1-0.9-2.0
Total zone transitions, hab. session 13.44.88.3-2.1-2.0-0.4-2.72.9-2.62.60.4-2.3
Total locomotion distance, hab. session 12.83.96.2-2.5-2.5-1.3-2.02.2-1.91.9-0.3-2.5
Locomotion velocity, hab. session 12.73.95.6-2.2-2.2-0.9-2.22.4-2.12.1-0.1-2.3
Time in familiar zone, hab. session 22.22.24.70.80.7-0.42.1-2.22.1-2.10.40.6
Time in novel zone, hab. session 20.80.91.6-0.6-0.40.1-1.21.3-1.31.3-0.7-0.5
Total zone transitions, hab. session 21.41.83.5-0.9-0.90.1-1.91.9-1.81.70.8-0.9
Total locomotion distance, hab. session 21.21.62.4-1.3-1.3-0.5-1.51.6-1.41.40.2-1.3
Locomotion velocity, hab. session 21.31.82.9-1.4-1.4-0.5-1.61.7-1.51.50.1-1.4
Novel to familiar place preference ratio1.11.14.21.41.31.00.4-0.50.3-0.30.82.0
Novelty place preference1.71.75.61.71.61.20.6-0.80.6-0.61.12.4
Time in novel zone, NPP test2.22.36.72.01.91.50.7-0.90.7-0.71.42.6
Total zone transitions, NPP test1.92.84.8-1.6-1.5-0.3-2.12.2-2.02.00.6-1.6
Total locomotion distance, NPP test1.21.72.5-1.4-1.4-0.5-1.51.6-1.41.40.2-1.5
Locomotion velocity, NPP test1.31.93.0-1.7-1.7-0.8-1.41.5-1.31.3-0.3-1.7
Pavlov. Cond. lever latency1.41.73.3-0.6-0.8-1.51.6-1.71.8-1.80.3-0.4
Pavlov. Cond. magazine entry latency0.50.61.0-0.7-0.8-0.3-0.91.0-0.90.9-0.3-0.8
Pavlov. Cond. change in total contacts1.92.14.40.10.21.1-2.12.0-2.12.10.10.3
Pavlov. Cond. index score1.21.53.2-0.1-0.00.8-1.81.8-1.81.80.3-0.1
Pavlov. Cond. latency score1.21.53.20.00.11.0-1.81.8-1.81.80.40.1
Pavlov. Cond. lever contacts2.22.65.6-0.00.21.3-2.22.4-2.42.3-0.4-0.2
Pavlov. Cond. magazine entry number0.50.71.50.40.5-0.11.2-1.21.1-1.1-0.50.1
Pavlov. Cond. intertrial magazine entries2.63.16.2-1.9-1.9-2.51.6-1.41.6-1.6-1.5-1.7
Pavlov. Cond. lever-magazine prob. diff.1.11.42.80.20.21.0-1.71.6-1.71.70.50.1
Pavlov. Cond. response bias1.21.53.4-0.3-0.30.6-1.81.8-1.81.8-0.2-0.3
Bone: apparent density0.40.61.4-0.7-0.5-0.81.0-0.60.8-0.8-1.2-0.7
Bone surface0.71.12.5-1.6-1.4-0.9-0.50.8-0.60.6-1.0-1.5
Bone volume0.71.22.7-1.4-1.3-1.30.6-0.10.3-0.3-1.6-1.4
Bone: connectivity density0.30.51.4-1.1-1.0-0.70.20.2-0.0-0.0-0.6-1.2
Bone: cortical apparent density0.40.50.9-0.8-0.9-0.6-0.70.6-0.60.60.1-0.8
Bone: cortical area0.40.61.41.01.01.2-0.60.5-0.60.60.60.8
Bone: cortical porosity0.10.10.20.20.1-0.10.4-0.50.5-0.50.40.0
Bone: cortical porosity0.20.20.4-0.3-0.4-0.60.5-0.60.6-0.60.3-0.4
Bone: cortical thickness0.10.20.20.40.50.5-0.40.3-0.40.4-0.10.4
Bone: cortical thickness1.11.23.10.90.91.2-1.20.8-1.01.01.80.9
Bone: cortical tissue density0.30.40.8-0.8-0.9-0.6-0.70.6-0.50.60.1-0.8
Bone: elastic displacement0.80.91.70.50.4-0.21.3-1.21.1-1.1-1.20.3
Bone: elastic work0.50.71.31.11.10.70.8-0.70.6-0.5-0.90.7
Bone: endosteal estimation0.92.04.5-1.1-0.80.3-2.02.1-2.02.00.2-0.5
Bone: endosteal perimeter0.10.20.5-0.10.10.4-0.60.7-0.70.7-0.40.1
Bone: final force1.82.96.4-0.7-0.50.7-2.52.5-2.42.40.6-0.6
Bone: final moment1.32.14.7-0.5-0.40.7-2.22.1-2.12.10.5-0.4
Bone: marrow area1.02.14.7-1.0-0.80.3-2.02.2-2.12.00.2-0.4
Bone: maximum diameter0.91.63.71.51.61.9-0.90.7-0.90.91.21.2
Bone: maximum force0.71.22.40.00.20.9-1.61.4-1.51.41.20.1
Bone: maximum moment0.50.91.70.20.30.9-1.31.2-1.21.21.20.2
Bone: minimum diameter1.01.83.9-0.5-0.10.7-1.81.9-1.92.0-0.9-0.0
Bone: periosteal estimation0.91.94.0-0.00.21.1-2.02.0-2.02.00.30.3
Bone: periosteal perimeter0.20.30.70.70.80.9-0.30.2-0.30.30.30.7
Bone: post-yield work0.40.63.0-0.8-0.9-0.70.0-0.10.2-0.31.7-0.5
Bone: stiffness0.60.92.4-0.8-0.8-0.1-1.21.1-1.01.01.6-0.4
Bone: tissue strength1.31.31.9-0.9-0.8-1.41.2-1.11.2-1.1-1.3-1.1
Bone: trabecular number0.00.10.2-0.10.00.00.4-0.20.3-0.3-0.3-0.1
Bone: trabecular spacing0.10.10.3-0.5-0.4-0.4-0.20.1-0.10.1-0.6-0.3
Bone: trabecular thickness1.01.22.90.80.90.21.7-1.41.4-1.4-1.00.4
Bone: trabecular tissue density0.20.30.7-0.5-0.7-0.90.1-0.30.4-0.30.6-0.7
Breakpoint value in progressive ratio session1.21.31.9-1.3-1.3-0.5-1.31.4-1.21.20.2-1.2
Distance traveled before self-admin2.42.55.90.90.81.7-1.91.6-1.71.62.41.1
Distance traveled after self-admin0.91.03.90.70.61.0-1.00.7-0.80.82.00.9
Delta time in closed arm before/after self-admin1.01.02.21.31.41.5-0.60.4-0.60.60.51.3
Delta time in open arm before/after self-admin0.10.10.2-0.4-0.4-0.40.3-0.10.2-0.20.0-0.4
Diff in mean of infusions in LGA sessions1.11.22.61.01.11.6-1.11.1-1.21.20.50.9
Extinction: sum of active levers before priming0.10.10.4-0.1-0.1-0.10.0-0.10.1-0.10.70.0
Active lever presses in extinction session 60.10.10.20.20.40.4-0.00.1-0.10.1-0.30.4
Delta distance traveled before/after self-admin1.01.11.81.01.00.31.3-1.31.2-1.2-0.70.8
Delta ambulatory time before/after self-admin1.31.43.10.60.6-0.31.8-1.71.7-1.6-0.80.4
Time in closed arm before self-admin2.12.44.1-0.6-0.7-1.62.0-1.92.0-1.9-1.6-0.6
Time in closed arm after self-admin0.70.71.20.90.80.21.0-1.11.0-0.9-0.20.9
Time in open arm before self-admin0.80.81.40.50.61.2-1.11.2-1.21.20.30.3
Time in open arm after self-admin1.31.42.8-0.1-0.00.9-1.71.7-1.61.60.9-0.1
Sum of active levers in priming session hrs 5-62.32.35.4-2.3-2.3-1.8-0.50.7-0.40.4-0.6-2.2
Time to tail flick, vehicle, before self-admin1.21.23.0-1.5-1.7-1.3-0.30.5-0.30.3-0.2-1.7
Time to tail flick, vehicle, after self-admin0.30.31.0-0.6-0.5-0.50.7-0.30.4-0.5-1.0-0.5
Time to tail flick, test, before self-admin0.10.10.50.20.10.1-0.0-0.10.1-0.10.70.0
Time to tail flick, test, after self-admin2.93.05.11.51.60.42.2-2.32.1-2.1-0.61.6
Delta time to tail flick, vehicle, before/after SA0.80.82.9-0.00.2-0.31.3-0.91.0-1.0-1.70.1
Delta time to tail flick, test, before/after SA1.31.12.11.11.20.61.1-1.21.1-1.10.31.4
Ambulatory time before self-admin1.61.73.80.60.51.3-1.61.4-1.41.42.00.7
Ambulatory time after self-admin0.20.20.60.50.50.5-0.20.1-0.20.20.80.6
Total heroin consumption0.50.61.2-1.1-1.0-1.00.10.00.1-0.0-1.0-1.0
Area under the delay curve1.61.84.70.1-0.10.7-1.81.5-1.61.52.20.1
Delay disc. indifference point, 0s delay0.30.31.20.50.50.6-0.40.3-0.30.31.10.6
Delay disc. indifference point, 16s delay0.50.50.80.70.60.9-0.80.6-0.70.70.70.6
Delay disc. indifference point, 2s delay3.64.08.3-1.5-1.40.0-2.92.8-2.72.70.7-1.3
Delay disc. indifference point, 24s delay0.90.82.01.41.31.00.5-0.60.5-0.50.51.3
Delay disc. indifference point, 4s delay3.33.49.10.50.51.5-2.42.0-2.12.03.00.7
Delay disc. indifference point, 8s delay0.60.64.6-0.0-0.20.1-0.70.5-0.40.42.20.0
Delay discount exponential model param1.41.54.30.10.2-0.51.7-1.41.4-1.4-2.10.1
Delay discount hyperbolic model param1.92.04.70.10.2-0.72.0-1.71.7-1.7-2.20.1
Fecal boli incidents, locomotor time 10.00.00.2-0.10.00.1-0.00.1-0.10.1-0.4-0.2
Change in fecal boli incidents, locomotor task1.21.11.81.01.00.41.4-1.31.2-1.2-0.31.2
Time >=10cm from walls, locomotor time 11.11.12.31.51.41.00.9-0.80.7-0.80.31.5
Bouts of movement, locomotor time 13.94.37.52.01.80.42.5-2.72.6-2.61.21.7
Total resting periods, locomotor time 13.03.36.01.61.50.32.4-2.52.3-2.30.41.5
Rest time, locomotor task time 10.30.30.5-0.4-0.4-0.70.6-0.70.7-0.70.3-0.5
Distance moved, locomotor task time 10.80.91.70.90.91.3-0.90.9-1.01.00.40.8
Vertical activity count, locomotor time 11.41.52.80.70.71.3-1.71.5-1.71.70.00.5
Time >=10cm from walls, locomotor time 20.30.30.80.70.80.60.6-0.40.4-0.4-0.20.9
Bouts of movement, locomotor time 21.61.74.01.20.90.21.2-1.51.4-1.42.01.2
Total resting periods, locomotor time 22.02.15.81.10.80.11.3-1.71.6-1.62.41.1
Rest time, locomotor task time 20.50.51.20.40.2-0.30.7-1.01.0-0.91.10.1
Distance moved, locomotor task time 20.60.71.4-0.00.10.7-1.11.2-1.21.20.20.3
Vertical activity count, locomotor time 23.23.57.5-0.10.21.4-2.72.6-2.72.7-0.40.2
Weight adjusted by age1.01.12.90.90.81.3-1.00.8-0.90.81.70.9
Seeking ratio, delayed vs. immediate footshock2.52.95.8-0.6-0.8-1.72.4-2.02.2-2.2-1.4-0.8
Locomotion in novel chamber2.63.37.4-0.2-0.11.1-2.72.6-2.62.60.6-0.2
Locomotion in novel chamber post-restriction0.20.20.9-0.5-0.6-0.5-0.30.2-0.10.10.9-0.6
Progressive ratio0.60.73.00.90.70.9-0.40.2-0.30.21.70.8
Food seeking constrained by brief footshock4.25.111.3-0.6-0.41.3-3.23.4-3.33.30.1-0.6
Seeking ratio, punishment vs. effort1.51.93.7-1.4-1.1-0.4-1.31.6-1.51.5-1.9-1.3
Run reversals in cocaine runway, females3.33.36.92.22.32.6-1.41.1-1.51.50.22.1
Run reversals in cocaine runway, males1.41.32.30.60.91.3-1.51.3-1.51.5-0.60.6
Latency to leave start box in cocaine runway1.01.12.20.30.4-0.41.5-1.41.4-1.3-1.20.3
Latency to leave start box in cocaine runway, F2.02.23.9-0.6-0.7-1.62.0-1.92.0-1.9-0.9-0.7
Latency to leave start box in cocaine runway, M0.40.40.80.60.70.8-0.20.3-0.40.4-0.90.8
Cd content in liver0.40.40.90.90.70.7-0.50.1-0.30.31.00.7
Co content in liver1.72.05.41.91.61.10.5-0.90.7-0.72.31.7
Cu content in liver0.20.20.5-0.6-0.7-0.5-0.10.2-0.10.10.2-0.7
Fe content in liver0.70.82.7-1.1-1.0-0.8-0.30.5-0.40.4-1.6-1.1
K content in liver0.40.41.40.60.70.30.7-0.50.5-0.4-1.20.5
Mg content in liver0.20.21.6-0.2-0.00.1-0.20.4-0.40.4-1.3-0.2
Mn content in liver0.40.51.10.50.40.01.0-0.90.9-1.00.20.4
Na content in liver0.10.10.20.20.10.3-0.40.4-0.40.4-0.10.0
Rb content in liver1.11.42.21.21.20.51.4-1.51.3-1.40.31.3
Se content in liver0.00.00.10.20.10.00.2-0.20.2-0.2-0.30.1
Sr content in liver0.90.81.90.91.01.4-0.70.8-0.90.80.40.9
Zn content in liver1.31.43.3-1.5-1.7-1.80.6-0.50.7-0.70.2-1.5