Hub : Genes

Zbtb40

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000022039 0.11 0.06 3.3e-16 0.11 0.1 0.1 0.11 1.4e-12 1.7e-11 1.6e-11 2.9e-12
2 BLA gene expression ENSRNOG00000022039 0.07 0.05 1.3e-04 0.08 0.05 0.06 0.07 6.6e-05 8.8e-04 5.6e-04 1.8e-04
3 Brain gene expression ENSRNOG00000022039 0.17 0.07 0.0e+00 0.21 0.22 0.23 0.23 1.9e-19 3.4e-20 3.3e-21 3.6e-21
4 IL gene expression ENSRNOG00000022039 0.14 0.08 2.1e-04 0.09 0.16 0.09 0.12 4.0e-03 9.4e-05 3.6e-03 9.0e-04
5 LHb gene expression ENSRNOG00000022039 0.21 0.12 8.5e-04 0.18 0.2 0.11 0.19 4.1e-05 1.8e-05 1.5e-03 3.5e-05
6 Liver gene expression ENSRNOG00000022039 0.04 0.02 1.7e-05 0.01 0.02 0.02 0.01 5.8e-02 1.4e-03 4.2e-03 1.2e-02
7 NAcc gene expression ENSRNOG00000022039 0.04 0.03 1.6e-04 0.03 0.02 0.02 0.02 1.4e-03 2.1e-02 1.8e-02 1.4e-02
8 PL gene expression ENSRNOG00000022039 0.14 0.07 2.4e-14 0.17 0.17 0.17 0.18 5.2e-13 3.7e-13 3.0e-13 7.7e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.72.37.1-1.0-1.5-1.9-1.10.2-0.5-2.7-1.7
BMI without tail0.81.63.7-0.8-1.4-1.1-1.3-0.9-1.1-1.9-1.3
Body weight2.711.318.1-2.7-3.2-2.5-3.8-3.4-3.3-4.2-3.4
Epididymis fat weight0.00.10.3-0.1-0.30.3-0.10.00.1-0.50.0
Glucose0.50.71.51.10.91.2-0.2-1.20.4-0.30.7
Heart weight0.10.20.60.00.4-0.0-0.5-0.8-0.1-0.4-0.2
Left kidney weight5.014.325.9-2.8-3.4-2.0-4.6-5.1-4.1-3.9-3.4
Right kidney weight1.64.512.6-1.3-1.7-0.6-2.7-3.5-2.4-1.6-1.7
Tail length1.02.910.2-0.8-1.10.2-2.1-3.2-2.3-1.1-0.9
Length with tail1.45.314.1-1.6-1.5-0.5-2.8-3.8-2.7-2.1-1.8
Length without tail1.53.24.5-1.8-1.5-1.5-2.0-1.8-1.7-2.1-1.9
Liver weight, left3.04.810.1-1.3-1.8-0.7-2.6-3.2-2.7-2.4-1.8
Liver weight, right2.33.85.4-1.7-1.9-1.4-2.3-2.3-2.3-1.6-1.9
Parametrial fat weight0.61.22.11.41.11.31.10.41.20.61.2
Retroperitoneal fat weight0.31.12.21.00.70.91.31.41.50.21.1
Intraocular pressure1.21.73.8-1.9-1.1-1.9-1.1-0.2-1.1-0.6-1.6
Extensor digitorum longus weight0.72.75.6-2.0-1.6-2.4-1.00.6-1.0-1.8-1.9
Soleus weight3.29.313.8-3.4-3.5-3.7-2.4-0.2-2.6-3.4-3.5
Tibialis anterior weight2.17.413.3-3.2-2.9-3.6-2.00.1-1.9-3.1-3.1
Tibia length1.13.04.2-1.7-1.7-1.2-1.9-1.8-2.1-1.6-1.7
Number of licking bursts0.20.20.40.60.60.50.50.20.60.40.5
Food consumed during 24 hour testing period0.10.10.60.3-0.00.5-0.2-0.7-0.10.30.2
Times rat made contact with spout0.30.42.20.00.60.20.30.10.31.50.4
Mean time between licks in bursts0.10.20.4-0.3-0.1-0.50.10.60.1-0.7-0.3
Mean num. licks in bursts0.10.10.4-0.50.0-0.2-0.3-0.4-0.40.6-0.2
Std. dev. time between licks in bursts1.11.32.9-1.6-1.0-1.7-0.8-0.1-1.0-0.6-1.4
Water consumed over 24 hours0.40.41.20.50.70.70.60.20.41.10.7
Indifference point 0 sec1.21.93.7-1.9-1.3-1.9-1.2-0.3-1.3-0.5-1.7
Indifference point AUC1.82.13.1-1.8-1.4-1.6-1.6-1.0-1.5-1.0-1.6
Indifference point function ln k1.82.64.01.61.41.52.01.81.61.31.6
Indifference point function log k1.82.64.01.61.41.52.01.81.61.31.6
Delay discounting total patch changes 0 sec1.11.73.4-1.8-1.3-1.8-1.1-0.2-1.2-0.3-1.6
Delay discounting total patch changes 12 sec2.53.34.5-2.1-1.7-1.9-2.0-1.6-2.1-0.6-2.0
Delay discounting total patch changes 18 sec2.63.55.2-2.3-2.2-1.9-2.0-1.3-2.1-0.5-2.0
Delay discounting total patch changes 24 sec2.63.25.6-2.4-2.0-2.4-1.7-0.5-1.6-0.9-2.1
Delay discounting total patch changes 6 sec3.04.67.3-2.7-1.8-2.5-2.4-1.5-2.2-1.0-2.5
Delay discounting time to switch 0 sec0.40.51.60.60.80.80.0-0.90.11.20.6
Delay discounting water rate 0 sec0.40.63.10.20.1-0.01.01.80.90.40.4
Delay discounting water rate 12 sec0.50.82.8-0.7-1.0-1.10.31.70.3-0.6-0.5
Delay discounting water rate 18 sec0.91.23.2-1.2-1.2-0.8-0.7-0.1-1.2-1.8-1.1
Delay discounting water rate 24 sec0.60.81.70.50.40.91.21.31.00.31.0
Delay discounting water rate 6 sec0.91.34.70.60.30.41.52.21.30.50.9
Locomotor activity6.29.914.2-3.3-3.4-3.2-3.1-1.8-2.9-3.8-3.3
Locomotor testing distance3.35.48.3-2.4-2.5-2.4-2.3-1.3-2.1-2.9-2.5
Locomotor testing rearing4.16.47.9-2.7-2.8-2.8-2.5-1.4-2.5-2.6-2.8
Light reinforcement 10.81.42.1-1.4-1.2-1.5-1.2-0.5-1.1-0.9-1.4
Light reinforcement 20.30.41.0-0.7-0.6-1.0-0.30.5-0.2-0.9-0.7
Reaction time number correct0.81.21.61.21.01.11.21.11.20.51.2
Reaction time mean minus median0.20.30.6-0.3-0.7-0.8-0.6-0.2-0.2-0.4-0.6
Reaction time mean minus median AUC0.30.40.8-0.3-0.8-0.7-0.9-0.6-0.4-0.2-0.6
Reaction time num false alarms0.40.61.0-0.8-0.6-0.9-0.7-0.3-0.6-1.0-0.9
Reaction time num false alarms AUC0.30.51.4-0.7-0.5-0.8-0.50.0-0.4-1.2-0.8
Reaction time trials correct on left0.81.21.61.21.01.11.21.11.20.51.2
Reaction time trials on left0.91.21.61.31.01.21.31.11.20.51.2
Reaction time mean0.20.20.7-0.3-0.8-0.3-0.6-0.4-0.60.2-0.5
Reaction time mean AUC0.10.10.30.2-0.40.1-0.00.0-0.00.60.0
Median of all reaction times0.10.10.20.1-0.50.2-0.1-0.2-0.30.5-0.0
Reaction time omissions0.00.10.3-0.2-0.5-0.3-0.10.1-0.1-0.0-0.2
Reaction time false alarm rate0.71.01.4-1.1-0.8-1.2-1.0-0.4-0.8-1.2-1.2
Reaction time premature initiation rate0.91.23.20.01.30.21.21.41.01.80.6
Reaction time premature initiations1.31.93.40.41.50.61.61.81.41.91.0
Std. dev. reaction times0.20.20.8-0.3-0.9-0.6-0.5-0.0-0.20.1-0.5
Reaction time trials completed0.91.21.61.31.01.21.31.11.20.51.2
Reaction time trials AUC0.71.01.51.20.91.11.10.81.10.31.1
Social response proportion0.40.41.60.31.20.60.60.30.80.30.6
Social responses1.92.44.3-2.0-1.3-1.7-1.4-0.5-1.2-2.1-1.8
Social time0.00.10.3-0.3-0.30.0-0.00.1-0.1-0.5-0.2
Conditioned locomotion2.32.74.61.51.21.31.81.61.72.11.6
Cocaine response after cond. corrected4.44.96.72.62.52.42.11.02.31.82.5
Cocaine response after cond. not corrected3.33.64.82.12.12.11.70.61.82.02.2
Cocaine response before conditioning1.62.03.2-1.5-1.4-1.1-1.7-1.6-1.8-0.6-1.3
Saline control response0.10.20.6-0.0-0.2-0.30.30.80.40.80.0
Condit. Reinf. active minus inactive responses0.70.81.8-0.8-1.0-1.2-0.60.3-0.5-1.3-1.0
Condit. Reinf. active-inactive response ratio1.41.52.31.31.31.01.41.31.50.61.2
Condit. Reinf. active responses4.56.38.9-2.6-3.0-2.8-2.3-0.9-2.4-2.8-2.8
Condit. Reinf. inactive responses10.312.817.0-3.7-4.1-3.4-3.6-2.4-3.9-3.3-3.8
Condit. Reinf. lever presses2.94.06.1-2.5-2.4-2.4-1.6-0.3-2.0-1.5-2.3
Condit. Reinf. lever reinforcers received4.36.18.5-2.6-2.9-2.6-2.3-1.0-2.4-2.7-2.7
Pavlov. Cond. lever latency1.82.54.42.02.11.81.30.31.70.81.7
Pavlov. Cond. magazine entry latency0.20.20.50.5-0.10.40.60.70.20.10.4
Pavlov. Cond. change in total contacts1.72.43.8-1.7-1.9-1.6-1.4-0.6-1.8-1.4-1.7
Pavlov. Cond. index score0.50.71.9-1.0-1.4-0.9-0.50.3-0.9-0.4-0.8
Pavlov. Cond. latency score0.40.51.2-0.8-1.1-0.8-0.20.6-0.6-0.2-0.6
Pavlov. Cond. lever contacts2.23.04.9-2.1-2.2-1.9-1.6-0.7-1.9-1.0-1.9
Pavlov. Cond. magazine entry number0.20.30.80.40.90.40.3-0.10.50.60.4
Pavlov. Cond. intertrial magazine entries1.41.83.81.81.32.01.0-0.30.91.11.6
Pavlov. Cond. lever-magazine prob. diff.0.60.82.1-1.0-1.4-0.9-0.50.3-0.9-0.4-0.8
Pavlov. Cond. response bias1.31.83.5-1.5-1.9-1.4-1.1-0.2-1.5-1.0-1.4
Conditioned reinforcement - actives0.70.71.8-0.7-0.8-0.3-0.9-1.0-0.9-1.3-0.6
Conditioned reinforcement - inactives1.31.42.4-1.6-1.3-1.0-1.2-0.8-1.1-1.3-1.2
Conditioned locomotion1.01.22.7-0.6-0.6-0.5-1.3-1.4-1.2-1.7-0.9
Intermittent access intake day 1-15 change2.42.44.2-1.8-2.0-1.5-1.2-0.3-1.3-2.0-1.5
Intermittent access intake escalation1.41.42.4-1.3-1.5-0.8-1.0-0.6-1.2-1.6-1.0
Intermittent access intake escalation 20.50.51.3-0.9-1.1-0.3-0.6-0.5-0.9-0.6-0.5
Intermitt. access day 1 inactive lever presses4.75.16.7-2.0-2.2-1.8-2.6-2.4-2.5-2.2-2.3
Intermitt. access day 15 inactive lever presses1.92.12.8-1.3-1.4-1.1-1.7-1.6-1.7-1.3-1.3
Intermitt. access escalation Index1.61.43.0-1.4-1.1-1.7-1.10.1-0.8-1.1-1.4
Intermittent access day 1 total infusions1.61.83.6-1.2-1.1-0.9-1.8-1.9-1.5-0.8-1.1
Intermittent access day 15 total infusions3.64.15.4-2.1-2.2-1.5-2.3-2.0-2.3-1.8-1.8
Intermittent access terminal intake (last 3 days)2.93.24.5-1.9-2.1-1.1-2.0-1.8-2.1-1.4-1.5
Intermittent access total infusions2.12.33.4-1.5-1.7-1.0-1.8-1.8-1.7-1.1-1.3
Intermittent access day 1 locomotion0.10.10.4-0.4-0.3-0.6-0.30.2-0.2-0.4-0.4
Intermittent access day 15 total locomotion0.10.10.3-0.4-0.10.20.10.1-0.10.50.2
Intermittent access total locomotion0.60.71.5-1.2-0.9-0.9-0.8-0.3-0.8-0.5-0.8
Intermittent access standard deviation4.34.57.9-2.0-1.9-1.7-2.2-1.8-2.2-2.8-2.1
Cocaine induced anxiety0.40.41.00.71.01.00.1-0.8-0.10.00.5
Post-drug Anxiety1.01.13.00.61.70.91.11.00.90.70.9
Baseline Anxiety1.01.15.2-0.6-0.0-1.00.92.31.0-0.0-0.2
Lifetime Intake1.41.62.7-1.3-1.3-0.7-1.6-1.6-1.5-0.8-1.0
Incentive Sensitization - Responses2.92.94.7-2.1-1.4-1.2-2.0-2.2-2.1-0.5-1.5
Incentive Sensitization - Breakpoint2.72.74.6-2.0-1.3-1.1-1.9-2.1-2.0-0.6-1.5
Progressive ratio test 1 active lever presses0.50.50.9-1.0-0.9-0.3-0.9-0.9-0.8-0.4-0.5
Progressive ratio test 1 breakpoint0.70.71.4-1.2-1.1-0.6-0.9-0.7-0.8-0.6-0.7
Progressive ratio test 1 inactive lever presses0.91.01.5-1.2-0.9-0.6-1.1-1.1-1.0-1.0-0.9
Progressive ratio test 2 active lever presses1.81.93.1-1.7-1.5-0.8-1.6-1.8-1.6-0.6-1.0
Progressive ratio test 2 breakpoint1.82.03.6-1.7-1.4-0.8-1.7-1.9-1.7-0.7-1.1
Progressive ratio test 2 inactive lever presses2.22.65.1-1.8-1.2-0.9-1.9-2.3-1.9-0.9-1.4
Total sessions with >9 infusions1.71.92.8-1.3-0.8-0.8-1.6-1.6-1.7-1.6-1.3
Short access day 1 total inactive lever presses0.50.50.9-0.8-0.8-0.9-0.6-0.1-0.8-0.4-0.9
Short access day 10 total inactive lever presses3.74.05.3-2.1-2.1-2.1-2.1-1.4-2.0-1.8-2.3
Short access day 1 total infusions1.92.03.4-1.8-1.1-1.0-1.7-1.4-1.5-1.3-1.3
Short access day 10 total infusions0.70.71.4-0.9-0.9-0.4-1.1-1.2-0.9-0.6-0.6
Short access total infusions0.50.51.2-0.7-0.5-0.2-0.9-1.1-0.8-0.6-0.4
Short access day 1 locomotion0.20.20.7-0.60.4-0.4-0.10.40.0-0.8-0.3
Short access day 10 total locomotion2.02.25.0-1.5-1.2-1.5-1.5-0.6-1.2-2.2-1.6
Short access total locomotion0.70.72.6-0.8-0.3-0.9-0.7-0.1-0.4-1.6-0.9
Compulsive drug intake1.91.83.0-1.1-0.9-0.8-1.6-1.7-1.6-1.5-1.3
One hour access (0.3 mA shock)4.45.17.5-2.7-2.4-1.9-2.4-2.0-2.5-1.9-2.2
One hour access (shock baseline)1.92.24.5-2.1-1.8-1.6-1.4-0.6-1.3-1.0-1.4
Number of responses in last shaping day0.10.10.2-0.2-0.2-0.3-0.3-0.1-0.1-0.4-0.3
Context. condit. distance diff. score1.62.03.0-1.6-1.7-1.4-1.5-0.8-1.4-1.0-1.5
Locomotion velocity, session 11.11.22.5-1.3-1.5-1.6-0.40.8-0.7-0.8-1.1
Locomotion distance, session 10.60.82.0-1.1-0.9-1.40.11.4-0.2-0.1-0.8
Locomotion velocity, session 22.22.63.91.41.61.12.01.81.61.61.6
Locomotion distance, session 21.11.52.6-1.6-1.4-1.6-0.70.3-1.1-1.2-1.4
Locomotion velocity, session 30.60.72.90.2-0.1-0.40.81.70.81.00.3
Locomotion distance, session 32.73.04.9-2.1-2.1-2.2-1.7-0.5-1.6-0.7-2.0
Stereotopy head waving bouts, day 31.11.31.81.31.11.31.20.71.00.91.3
Stereotopy head waving duration, day 32.22.74.42.11.82.11.60.61.41.11.9
Locomotion velocity, session 72.73.05.1-1.8-2.3-1.5-2.0-1.4-1.9-1.1-1.7
Locomotion distance, session 70.40.51.0-0.7-1.0-0.4-0.8-0.7-0.8-0.6-0.7
Stereotopy head waving bouts, day 70.00.00.10.40.20.10.1-0.00.20.00.2
Stereotopy head waving duration, day 70.10.10.20.30.10.2-0.1-0.5-0.1-0.30.1
Locomotion velocity, session 80.20.30.9-0.4-0.6-0.70.11.00.1-0.4-0.4
Locomotion distance, session 82.74.06.4-2.5-2.4-2.5-1.7-0.2-1.7-1.6-2.3
Degree of sensitization distance3.13.16.32.31.82.51.60.41.50.82.1
Degree of sensitization stereotypy0.40.41.0-0.4-0.5-0.4-0.8-1.0-0.6-0.7-0.6
Condit. Reinf. active minus inactive responses1.31.52.81.41.51.71.10.20.90.81.4
Condit. Reinf. active-inactive response ratio1.71.94.11.81.62.01.1-0.11.00.71.6
Condit. Reinf. active responses0.30.41.10.60.61.00.3-0.4-0.10.60.7
Condit. Reinf. inactive responses0.70.91.9-1.1-1.1-0.7-0.9-0.8-1.4-0.1-0.8
Incentive salience index mean0.40.41.20.60.71.10.4-0.30.00.80.8
Condit. Reinf. lever presses0.40.61.6-0.8-0.6-0.2-0.7-0.9-1.30.2-0.5
Time in familiar zone, hab. session 10.10.10.2-0.5-0.3-0.3-0.4-0.3-0.20.5-0.3
Time in novel zone, hab. session 10.20.10.30.60.40.40.40.20.4-0.10.4
Total zone transitions, hab. session 10.60.92.0-1.4-0.9-1.3-0.60.1-0.9-0.4-1.1
Total locomotion distance, hab. session 10.81.12.4-1.5-0.9-1.4-0.7-0.2-1.1-0.4-1.2
Locomotion velocity, hab. session 10.50.71.7-1.3-0.7-1.1-0.5-0.1-1.0-0.2-1.0
Time in familiar zone, hab. session 20.20.20.7-0.5-0.2-0.1-0.3-0.4-0.50.8-0.2
Time in novel zone, hab. session 20.60.61.20.90.60.40.91.01.10.00.7
Total zone transitions, hab. session 21.72.24.1-1.9-2.0-2.0-0.80.6-1.2-0.9-1.6
Total locomotion distance, hab. session 21.01.32.9-1.5-1.4-1.7-0.30.9-0.8-0.3-1.2
Locomotion velocity, hab. session 21.52.04.2-1.9-1.7-2.0-0.70.5-1.2-0.8-1.6
Novel to familiar place preference ratio0.60.61.31.10.91.10.3-0.50.6-0.10.9
Novelty place preference0.40.51.01.00.71.00.0-0.80.3-0.20.7
Time in novel zone, NPP test0.50.51.11.00.71.00.0-0.80.4-0.10.7
Total zone transitions, NPP test0.60.81.9-1.1-1.2-1.4-0.30.8-0.5-0.4-0.9
Total locomotion distance, NPP test0.40.51.0-1.0-1.0-1.0-0.20.5-0.70.1-0.7
Locomotion velocity, NPP test0.50.71.4-1.1-1.0-1.2-0.20.6-0.8-0.2-0.9
Pavlov. Cond. lever latency0.10.20.30.60.50.50.1-0.30.50.10.4
Pavlov. Cond. magazine entry latency0.20.30.4-0.7-0.7-0.7-0.5-0.2-0.7-0.1-0.7
Pavlov. Cond. change in total contacts0.10.10.4-0.2-0.1-0.30.20.6-0.10.2-0.2
Pavlov. Cond. index score0.30.40.7-0.8-0.7-0.7-0.5-0.2-0.8-0.4-0.7
Pavlov. Cond. latency score0.20.30.5-0.7-0.6-0.7-0.40.0-0.7-0.2-0.7
Pavlov. Cond. lever contacts0.10.10.3-0.3-0.3-0.30.20.6-0.40.1-0.2
Pavlov. Cond. magazine entry number1.92.43.31.71.71.41.61.21.80.91.7
Pavlov. Cond. intertrial magazine entries7.59.011.63.03.13.23.12.03.03.03.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.3-0.4-0.3-0.20.1-0.4-0.2-0.4
Pavlov. Cond. response bias0.70.91.4-1.1-1.2-1.0-0.8-0.3-1.2-0.4-1.0
Bone: apparent density1.52.43.8-2.0-1.6-1.8-1.3-0.4-1.5-1.6-1.8
Bone surface1.52.63.6-1.9-1.7-1.7-1.4-0.6-1.6-1.8-1.8
Bone volume1.42.43.4-1.9-1.6-1.5-1.4-0.7-1.6-1.6-1.7
Bone: connectivity density0.91.42.4-1.5-1.0-1.4-1.1-0.6-1.2-0.9-1.4
Bone: cortical apparent density0.30.31.80.10.20.6-0.6-1.3-0.40.20.1
Bone: cortical area4.06.18.3-2.9-2.6-2.3-2.6-1.8-2.7-1.9-2.6
Bone: cortical porosity1.11.22.71.11.21.11.10.50.71.71.2
Bone: cortical porosity2.52.73.41.71.81.71.70.91.41.81.8
Bone: cortical thickness2.23.66.1-2.5-1.9-2.1-1.9-1.1-1.9-1.2-2.1
Bone: cortical thickness0.70.82.1-1.4-0.9-1.5-0.40.6-0.50.3-1.0
Bone: cortical tissue density0.20.31.40.30.40.8-0.3-1.2-0.10.40.4
Bone: elastic displacement0.30.41.0-1.0-0.1-0.9-0.20.2-0.40.7-0.6
Bone: elastic work0.81.12.6-1.6-0.9-1.6-0.70.0-0.9-0.1-1.2
Bone: endosteal estimation1.53.25.0-1.4-1.7-0.8-1.9-2.0-2.2-2.2-1.6
Bone: endosteal perimeter1.22.64.0-1.5-1.8-1.2-1.5-1.0-1.8-2.0-1.7
Bone: final force3.04.96.7-2.6-2.4-2.1-2.4-1.7-2.4-1.6-2.3
Bone: final moment3.45.77.8-2.8-2.6-2.3-2.5-1.6-2.5-2.0-2.5
Bone: marrow area1.53.25.1-1.4-1.6-0.8-1.9-2.0-2.2-2.3-1.6
Bone: maximum diameter3.25.97.4-2.4-2.7-1.9-2.5-1.9-2.7-2.6-2.4
Bone: maximum force3.76.48.1-2.8-2.8-2.3-2.6-1.9-2.8-2.1-2.6
Bone: maximum moment4.37.59.6-3.1-3.1-2.6-2.7-1.8-3.0-2.5-2.9
Bone: minimum diameter1.62.96.1-1.5-1.3-0.6-1.9-2.5-2.3-1.2-1.4
Bone: periosteal estimation3.36.89.4-2.6-2.7-1.9-2.8-2.4-3.1-2.7-2.6
Bone: periosteal perimeter3.96.58.5-2.8-2.8-2.2-2.6-1.8-2.9-2.3-2.7
Bone: post-yield work0.30.30.90.2-0.50.4-0.4-0.8-0.7-0.9-0.1
Bone: stiffness3.96.27.7-2.5-2.7-1.9-2.6-2.1-2.8-2.7-2.5
Bone: tissue strength1.01.03.2-0.6-1.1-0.9-0.8-0.4-0.8-1.8-1.0
Bone: trabecular number0.61.01.9-1.3-1.1-1.4-0.60.3-0.7-1.0-1.1
Bone: trabecular spacing1.52.02.91.61.71.71.30.51.41.21.6
Bone: trabecular thickness1.21.52.3-1.1-1.3-0.7-1.4-1.4-1.5-0.9-1.2
Bone: trabecular tissue density0.20.31.10.1-0.20.2-0.5-1.0-0.5-0.6-0.2
Breakpoint value in progressive ratio session0.30.30.7-0.6-0.4-0.2-0.6-0.8-0.60.6-0.3
Distance traveled before self-admin5.35.78.0-2.4-2.1-1.9-2.8-2.6-2.5-2.3-2.3
Distance traveled after self-admin4.65.16.9-2.4-2.6-2.0-2.5-1.9-2.4-1.8-2.3
Delta time in closed arm before/after self-admin0.30.30.80.60.80.90.3-0.50.00.20.3
Delta time in open arm before/after self-admin0.10.10.30.30.30.50.0-0.30.1-0.00.5
Diff in mean of infusions in LGA sessions0.20.21.20.10.40.40.2-0.0-0.01.10.3
Extinction: sum of active levers before priming0.70.71.4-0.6-0.5-0.6-0.9-1.0-0.9-1.2-0.9
Active lever presses in extinction session 60.40.40.80.40.90.80.3-0.40.30.80.7
Delta distance traveled before/after self-admin0.10.10.3-0.0-0.50.1-0.00.0-0.30.60.0
Delta ambulatory time before/after self-admin0.10.20.80.3-0.00.20.40.40.10.90.2
Time in closed arm before self-admin3.33.85.7-1.6-2.0-1.4-2.4-2.2-2.1-1.9-1.8
Time in closed arm after self-admin0.50.52.30.0-0.20.4-0.8-1.5-0.9-0.3-0.3
Time in open arm before self-admin0.70.81.50.60.90.31.11.10.91.20.6
Time in open arm after self-admin2.02.23.01.51.61.51.51.01.61.11.7
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.1-0.3-0.4-0.4-0.2-0.6-0.4
Time to tail flick, vehicle, before self-admin1.51.52.61.51.20.81.31.51.6-0.60.9
Time to tail flick, vehicle, after self-admin0.80.92.11.41.01.30.7-0.40.70.11.1
Time to tail flick, test, before self-admin0.30.30.7-0.6-0.1-0.8-0.40.1-0.3-0.7-0.7
Time to tail flick, test, after self-admin0.30.41.20.30.30.4-0.5-1.1-0.5-0.9-0.1
Delta time to tail flick, vehicle, before/after SA0.30.31.5-0.1-0.20.1-0.5-1.2-0.60.1-0.1
Delta time to tail flick, test, before/after SA0.30.30.90.80.40.90.1-0.5-0.1-0.40.5
Ambulatory time before self-admin4.64.86.6-2.2-2.3-1.6-2.6-2.4-2.5-1.8-2.0
Ambulatory time after self-admin4.24.76.3-2.2-2.5-1.8-2.4-2.0-2.5-1.5-2.1
Total heroin consumption0.40.40.7-0.8-0.5-0.8-0.8-0.6-0.5-0.4-0.7
Area under the delay curve0.10.10.40.20.2-0.00.20.60.3-0.70.1
Delay disc. indifference point, 0s delay0.60.61.1-0.9-0.6-1.0-0.11.0-0.1-1.0-0.8
Delay disc. indifference point, 16s delay0.10.10.8-0.1-0.3-0.1-0.2-0.1-0.2-0.9-0.2
Delay disc. indifference point, 2s delay0.20.20.50.50.6-0.10.20.50.4-0.70.0
Delay disc. indifference point, 24s delay0.40.41.00.71.00.80.5-0.10.40.10.8
Delay disc. indifference point, 4s delay0.10.10.70.1-0.10.10.20.40.2-0.80.2
Delay disc. indifference point, 8s delay0.10.10.5-0.0-0.1-0.30.10.70.2-0.5-0.1
Delay discount exponential model param0.10.10.4-0.4-0.3-0.1-0.2-0.5-0.30.7-0.2
Delay discount hyperbolic model param0.20.20.5-0.4-0.3-0.1-0.2-0.6-0.30.7-0.2
Fecal boli incidents, locomotor time 13.63.95.2-1.7-1.3-1.8-2.3-2.3-2.0-2.0-2.2
Change in fecal boli incidents, locomotor task5.75.47.42.21.72.02.72.52.71.82.7
Time >=10cm from walls, locomotor time 10.50.51.4-0.1-0.6-0.2-1.0-1.2-0.7-0.8-0.4
Bouts of movement, locomotor time 10.70.71.40.41.10.20.91.01.20.80.7
Total resting periods, locomotor time 10.60.61.30.31.10.30.80.91.20.70.7
Rest time, locomotor task time 12.12.33.91.51.92.01.20.01.61.21.8
Distance moved, locomotor task time 11.11.22.1-1.0-1.4-1.4-0.70.4-0.8-1.2-1.3
Vertical activity count, locomotor time 12.32.44.4-1.6-1.9-2.1-1.10.4-1.4-1.5-1.8
Time >=10cm from walls, locomotor time 20.10.10.3-0.1-0.1-0.1-0.4-0.60.1-0.2-0.1
Bouts of movement, locomotor time 22.02.23.31.41.81.31.51.11.71.41.5
Total resting periods, locomotor time 23.13.34.61.72.11.71.81.22.11.71.9
Rest time, locomotor task time 22.32.64.21.81.82.11.20.01.51.72.0
Distance moved, locomotor task time 21.51.72.6-1.5-1.6-1.0-1.2-0.6-1.3-1.4-1.4
Vertical activity count, locomotor time 22.62.83.8-1.9-1.9-1.8-1.4-0.3-1.7-1.8-1.9
Weight adjusted by age0.40.41.30.90.61.10.2-0.50.40.10.7
Seeking ratio, delayed vs. immediate footshock1.82.13.8-1.7-1.9-2.0-1.00.5-0.8-1.5-1.6
Locomotion in novel chamber2.93.67.2-2.1-2.4-2.7-1.50.5-0.9-1.9-2.2
Locomotion in novel chamber post-restriction0.40.50.8-0.6-0.6-0.7-0.8-0.5-0.9-0.8-0.8
Progressive ratio0.10.10.30.5-0.00.4-0.1-0.6-0.20.10.0
Food seeking constrained by brief footshock0.40.52.10.40.61.0-0.3-1.5-0.30.40.4
Seeking ratio, punishment vs. effort0.00.00.1-0.20.30.1-0.1-0.3-0.1-0.10.1
Run reversals in cocaine runway, females0.50.51.0-1.0-0.8-1.0-0.7-0.2-0.6-0.3-0.8
Run reversals in cocaine runway, males0.20.20.4-0.2-0.1-0.3-0.7-0.6-0.1-0.5-0.4
Latency to leave start box in cocaine runway0.91.01.71.31.20.91.00.70.91.01.1
Latency to leave start box in cocaine runway, F0.10.10.30.40.4-0.10.20.50.3-0.10.1
Latency to leave start box in cocaine runway, M4.34.26.22.41.82.12.11.01.72.52.3
Cd content in liver2.02.13.7-1.8-1.4-1.9-1.4-0.4-1.1-1.3-1.7
Co content in liver0.40.51.1-1.0-0.6-0.9-0.5-0.1-0.80.4-0.8
Cu content in liver0.70.82.60.90.50.90.70.40.71.61.0
Fe content in liver0.20.20.5-0.4-0.7-0.6-0.10.5-0.2-0.5-0.4
K content in liver0.30.30.70.80.40.60.60.50.60.20.6
Mg content in liver0.00.00.10.30.00.10.10.10.3-0.10.1
Mn content in liver0.70.82.7-0.7-0.6-0.6-0.8-0.7-0.8-1.7-0.9
Na content in liver1.71.83.2-1.3-1.8-1.3-1.2-0.7-1.5-1.3-1.4
Rb content in liver0.10.21.00.20.30.3-0.4-1.0-0.2-0.00.0
Se content in liver2.63.25.02.21.92.11.71.01.91.12.0
Sr content in liver2.01.82.9-1.6-1.7-1.7-0.80.3-1.2-1.4-1.5
Zn content in liver1.41.52.3-1.1-1.4-1.1-1.5-1.3-1.4-0.5-1.3