Slc16a12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021916 0.25 0.1 6.7e-16 0.11 0.14 0.14 0.11 5.1e-12 1.3e-15 3.5e-15 1.8e-12
2 BLA intron excision ratio chr1:232208693:232261522 0.05 0.03 2.5e-03 0.04 0.03 0.03 0.03 4.9e-03 6.1e-03 1.5e-02 1.4e-02
3 Brain intron excision ratio chr1:232208693:232261522 0.04 0.03 2.3e-04 0.03 0.04 0.04 0.04 5.3e-04 8.3e-05 1.4e-04 1.0e-04
4 Liver gene expression ENSRNOG00000021916 0.03 0.02 1.4e-03 0 0.01 0.01 0.01 8.9e-02 6.7e-03 1.5e-02 4.1e-02
5 Liver intron excision ratio chr1:232208693:232260778 0.15 0.07 0.0e+00 0.14 0.18 0.17 0.16 1.4e-15 2.7e-19 1.2e-18 1.7e-17
6 Liver intron excision ratio chr1:232208693:232261522 0.24 0.09 0.0e+00 0.22 0.25 0.25 0.25 1.8e-23 1.9e-27 8.5e-28 3.1e-27
7 Liver intron excision ratio chr1:232253397:232260778 0.05 0.03 6.1e-07 0.01 0.03 0.02 0.03 1.1e-02 2.3e-04 1.1e-03 4.2e-04
8 Liver intron excision ratio chr1:232260950:232261522 0.14 0.07 0.0e+00 0.14 0.14 0.14 0.14 3.6e-15 4.3e-15 7.9e-16 8.5e-15
9 Liver mRNA stability ENSRNOG00000021916 0.11 0.05 1.4e-14 0.12 0.1 0.1 0.09 1.1e-13 1.7e-11 1.2e-11 4.0e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.96.110.3-3.2-2.8-2.21.52.7-2.72.23.0-1.3
BMI without tail0.10.20.50.0-0.4-0.70.30.5-0.30.20.6-0.6
Body weight0.31.23.4-1.1-1.6-0.80.90.9-1.00.81.90.2
Epididymis fat weight0.81.83.5-0.8-1.9-1.31.61.3-1.41.31.5-0.7
Glucose0.20.30.7-0.5-0.7-0.50.50.6-0.90.60.6-0.2
Heart weight0.30.41.31.20.5-0.3-0.3-0.20.5-0.5-0.3-1.0
Left kidney weight0.82.34.4-1.1-2.1-1.41.81.4-1.41.51.8-0.6
Right kidney weight0.51.42.8-0.0-1.7-1.21.70.9-1.01.01.4-0.9
Tail length1.64.89.73.11.71.9-1.4-2.42.5-2.4-1.82.0
Length with tail0.62.14.02.00.81.4-0.5-1.71.7-1.5-0.71.9
Length without tail0.40.81.7-1.2-1.20.10.80.3-0.60.61.31.2
Liver weight, left0.10.20.50.0-0.40.20.7-0.30.20.2-0.00.7
Liver weight, right1.01.74.7-1.3-2.2-0.91.21.2-1.41.11.60.1
Parametrial fat weight0.30.51.11.00.40.7-0.3-0.90.7-0.8-0.40.8
Retroperitoneal fat weight1.24.16.3-1.7-2.1-2.21.52.2-2.21.72.5-1.7
Intraocular pressure1.11.63.31.81.70.6-0.9-1.11.5-1.2-1.20.0
Extensor digitorum longus weight0.20.92.4-1.5-1.3-0.3-0.10.8-0.90.41.50.7
Soleus weight0.30.92.30.30.71.0-1.5-0.70.9-1.1-0.80.9
Tibialis anterior weight0.31.15.0-1.4-0.91.0-0.7-0.2-0.2-0.30.92.2
Tibia length0.82.23.51.51.01.7-1.1-1.71.6-1.6-1.21.9
Number of licking bursts9.110.813.4-2.3-3.2-3.73.33.6-3.63.33.3-3.2
Food consumed during 24 hour testing period0.20.31.41.20.6-0.3-0.0-0.20.5-0.4-0.1-0.5
Times rat made contact with spout0.10.10.2-0.2-0.5-0.20.50.2-0.30.30.50.2
Mean time between licks in bursts0.71.04.40.00.1-1.40.31.1-0.70.60.5-2.1
Mean num. licks in bursts9.911.914.52.73.43.8-3.3-3.83.8-3.5-3.43.3
Std. dev. time between licks in bursts1.31.57.40.30.2-1.70.81.2-0.80.90.2-2.7
Water consumed over 24 hours0.60.81.2-0.5-1.0-1.10.81.0-0.80.81.1-0.6
Indifference point 0 sec0.91.55.22.31.30.6-0.1-1.21.4-0.9-1.3-0.1
Indifference point AUC0.20.30.91.00.10.3-0.5-0.50.6-0.7-0.3-0.1
Indifference point function ln k0.40.51.7-1.3-0.6-0.30.80.6-0.70.90.50.2
Indifference point function log k0.40.51.7-1.3-0.6-0.30.80.6-0.70.90.50.2
Delay discounting total patch changes 0 sec0.71.14.42.11.00.30.1-1.01.1-0.7-1.1-0.3
Delay discounting total patch changes 12 sec0.81.13.31.80.80.6-0.8-1.01.1-1.2-1.00.1
Delay discounting total patch changes 18 sec0.20.31.41.20.30.1-0.2-0.50.6-0.5-0.5-0.3
Delay discounting total patch changes 24 sec0.70.93.92.00.60.4-0.0-1.01.1-0.8-0.9-0.1
Delay discounting total patch changes 6 sec1.72.67.52.71.31.2-0.9-1.81.8-1.6-1.60.6
Delay discounting time to switch 0 sec1.62.43.8-1.7-1.5-1.41.61.6-1.91.71.4-1.1
Delay discounting water rate 0 sec1.62.53.51.71.81.3-1.6-1.61.9-1.7-1.41.0
Delay discounting water rate 12 sec1.01.53.51.91.31.1-0.5-1.51.4-1.1-1.30.7
Delay discounting water rate 18 sec0.30.31.00.50.30.7-0.1-0.70.4-0.4-0.51.0
Delay discounting water rate 24 sec1.21.62.41.40.91.4-0.6-1.51.3-1.2-1.21.6
Delay discounting water rate 6 sec0.20.30.70.60.80.5-0.3-0.60.7-0.4-0.70.0
Locomotor activity1.01.72.1-0.8-1.2-1.41.31.3-1.41.31.4-1.4
Locomotor testing distance2.54.15.4-1.4-1.8-2.32.22.1-2.02.11.8-2.3
Locomotor testing rearing2.64.05.9-2.1-2.1-2.21.22.4-2.01.72.4-1.5
Light reinforcement 10.61.03.21.81.40.4-0.5-0.90.9-0.9-1.2-0.3
Light reinforcement 21.31.74.32.11.70.6-0.8-1.11.1-1.1-1.8-0.4
Reaction time number correct1.92.74.41.81.41.8-1.1-1.91.7-1.5-2.11.2
Reaction time mean minus median0.20.30.80.50.80.2-0.3-0.30.7-0.3-0.9-0.3
Reaction time mean minus median AUC0.60.81.81.01.20.5-0.5-0.81.0-0.6-1.3-0.2
Reaction time num false alarms1.62.23.5-1.4-1.9-1.41.51.5-1.61.51.7-0.6
Reaction time num false alarms AUC1.62.23.2-1.0-1.8-1.61.51.6-1.71.41.7-1.0
Reaction time trials correct on left1.92.74.41.81.41.8-1.1-1.91.7-1.5-2.11.2
Reaction time trials on left1.82.64.41.81.31.7-1.1-1.91.7-1.5-2.11.2
Reaction time mean0.40.51.4-0.5-0.3-0.90.40.9-0.50.70.4-1.2
Reaction time mean AUC0.30.41.2-0.4-0.2-0.80.40.8-0.40.60.1-1.1
Median of all reaction times0.50.71.6-0.7-0.5-1.10.51.1-0.80.80.6-1.3
Reaction time omissions0.30.42.10.2-0.1-0.80.50.5-0.30.5-0.2-1.4
Reaction time false alarm rate3.55.07.1-2.1-2.4-2.32.02.4-2.52.12.7-1.4
Reaction time premature initiation rate0.40.51.4-0.8-1.20.20.5-0.0-0.20.40.91.1
Reaction time premature initiations0.71.03.30.5-0.11.4-0.3-1.31.0-0.8-0.61.8
Std. dev. reaction times0.10.21.00.30.3-0.50.10.30.20.2-0.5-1.0
Reaction time trials completed1.82.64.41.81.31.7-1.1-1.91.7-1.5-2.11.2
Reaction time trials AUC1.72.44.01.81.31.6-1.1-1.81.6-1.4-2.01.0
Social response proportion0.20.21.2-1.1-0.10.3-0.50.1-0.30.00.30.6
Social responses0.10.10.2-0.30.20.4-0.2-0.20.2-0.1-0.30.4
Social time0.00.10.20.40.2-0.10.4-0.10.10.1-0.3-0.3
Conditioned locomotion1.72.02.91.01.11.6-1.6-1.51.5-1.6-1.01.7
Cocaine response after cond. corrected0.91.01.21.00.91.0-1.0-1.01.1-1.1-0.90.8
Cocaine response after cond. not corrected1.01.21.51.20.71.2-0.8-1.21.1-1.1-1.01.2
Cocaine response before conditioning0.10.10.30.6-0.20.10.4-0.20.1-0.0-0.20.3
Saline control response2.23.05.31.01.32.0-1.8-1.91.8-1.8-1.12.3
Condit. Reinf. active minus inactive responses0.30.40.7-0.3-0.5-0.70.90.6-0.50.70.7-0.5
Condit. Reinf. active-inactive response ratio0.50.60.6-0.7-0.8-0.80.80.8-0.80.80.8-0.4
Condit. Reinf. active responses0.00.00.10.20.0-0.30.20.00.20.00.3-0.1
Condit. Reinf. inactive responses0.40.51.01.00.80.5-0.6-0.80.9-0.9-0.30.5
Condit. Reinf. lever presses0.10.10.20.40.3-0.10.1-0.20.4-0.1-0.2-0.3
Condit. Reinf. lever reinforcers received0.10.10.30.1-0.1-0.50.50.2-0.00.30.4-0.4
Pavlov. Cond. lever latency2.02.75.9-2.4-2.0-1.11.01.6-2.01.52.0-0.1
Pavlov. Cond. magazine entry latency0.20.31.01.00.3-0.50.20.10.2-0.1-0.2-0.9
Pavlov. Cond. change in total contacts0.30.41.31.10.60.4-0.3-0.70.8-0.6-0.70.2
Pavlov. Cond. index score0.70.92.81.71.10.4-0.5-0.81.2-0.9-0.9-0.1
Pavlov. Cond. latency score0.81.02.71.61.10.6-0.6-1.01.3-1.0-1.10.2
Pavlov. Cond. lever contacts2.02.85.52.42.01.1-1.2-1.72.1-1.7-1.80.4
Pavlov. Cond. magazine entry number0.20.21.0-1.0-0.30.4-0.3-0.0-0.30.00.20.8
Pavlov. Cond. intertrial magazine entries1.41.93.0-1.5-1.7-1.01.41.2-1.51.41.6-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.62.51.60.90.1-0.3-0.60.9-0.7-0.8-0.3
Pavlov. Cond. response bias1.11.54.82.21.40.4-0.6-1.01.5-1.1-1.2-0.3
Conditioned reinforcement - actives0.40.41.1-0.8-0.90.20.30.1-0.30.30.51.1
Conditioned reinforcement - inactives0.91.03.8-0.20.41.4-0.5-1.20.8-0.6-0.62.0
Conditioned locomotion1.01.11.9-0.10.91.4-1.4-1.11.1-1.1-0.71.4
Intermittent access intake day 1-15 change0.10.10.4-0.3-0.40.40.0-0.20.10.0-0.10.6
Intermittent access intake escalation0.20.20.5-0.7-0.7-0.10.60.2-0.30.50.20.3
Intermittent access intake escalation 20.40.41.1-1.1-0.9-0.10.70.4-0.60.80.30.2
Intermitt. access day 1 inactive lever presses0.20.30.50.40.70.5-0.3-0.70.5-0.4-0.60.1
Intermitt. access day 15 inactive lever presses0.90.91.50.50.91.2-0.7-1.21.2-0.8-1.20.9
Intermitt. access escalation Index0.20.20.6-0.7-0.5-0.2-0.00.4-0.30.20.40.4
Intermittent access day 1 total infusions0.20.30.8-0.9-0.60.0-0.00.3-0.30.20.80.7
Intermittent access day 15 total infusions0.50.61.3-1.1-1.10.10.40.3-0.40.40.91.1
Intermittent access terminal intake (last 3 days)0.91.02.9-1.7-1.4-0.10.60.5-0.80.81.11.0
Intermittent access total infusions1.11.23.1-1.8-1.5-0.40.70.9-1.10.91.40.7
Intermittent access day 1 locomotion0.60.61.7-1.3-0.9-0.4-0.10.7-0.60.31.30.2
Intermittent access day 15 total locomotion0.70.72.0-0.20.51.1-1.2-0.70.6-0.9-0.21.4
Intermittent access total locomotion0.60.72.2-1.5-1.0-0.20.10.6-0.80.51.20.5
Intermittent access standard deviation0.20.20.6-0.5-0.40.00.80.1-0.30.60.10.2
Cocaine induced anxiety0.00.00.20.3-0.1-0.20.20.1-0.20.1-0.0-0.4
Post-drug Anxiety1.61.83.31.51.51.3-0.9-1.51.3-1.1-1.80.7
Baseline Anxiety1.81.92.71.41.61.4-1.2-1.41.5-1.4-1.60.9
Lifetime Intake1.21.33.0-1.7-1.6-0.50.70.9-1.20.91.50.6
Incentive Sensitization - Responses3.03.06.2-2.5-2.2-1.11.31.6-1.81.62.10.3
Incentive Sensitization - Breakpoint1.91.94.4-2.1-1.9-0.71.01.1-1.41.31.60.5
Progressive ratio test 1 active lever presses0.90.93.1-0.20.41.2-1.2-0.80.7-1.0-0.21.8
Progressive ratio test 1 breakpoint0.70.72.5-0.20.31.0-1.1-0.70.6-0.8-0.11.6
Progressive ratio test 1 inactive lever presses0.60.71.70.20.31.0-0.9-0.80.8-0.9-0.31.3
Progressive ratio test 2 active lever presses1.31.44.4-2.1-1.5-0.10.50.7-0.90.81.41.3
Progressive ratio test 2 breakpoint0.91.03.3-1.8-1.30.10.20.4-0.70.51.21.5
Progressive ratio test 2 inactive lever presses0.91.03.6-1.9-1.20.30.60.3-0.70.80.91.4
Total sessions with >9 infusions0.30.30.9-0.8-0.7-0.2-0.10.5-0.60.20.90.5
Short access day 1 total inactive lever presses0.50.62.1-1.5-0.50.6-0.6-0.0-0.1-0.00.61.3
Short access day 10 total inactive lever presses0.20.20.40.30.10.6-0.3-0.60.6-0.4-0.30.6
Short access day 1 total infusions1.11.12.6-1.6-1.4-0.40.40.9-1.20.71.50.6
Short access day 10 total infusions0.60.60.9-0.9-0.9-0.60.70.8-0.90.80.8-0.4
Short access total infusions0.50.61.4-1.1-1.2-0.20.30.6-0.80.51.00.7
Short access day 1 locomotion0.91.01.9-1.3-1.3-0.70.31.0-1.30.71.4-0.1
Short access day 10 total locomotion0.70.81.8-1.3-1.1-0.50.20.9-1.10.61.2-0.3
Short access total locomotion1.01.02.0-1.2-1.2-0.80.41.0-1.20.71.4-0.4
Compulsive drug intake2.42.43.11.31.21.7-1.7-1.61.6-1.8-1.31.8
One hour access (0.3 mA shock)0.91.03.90.10.01.4-0.7-1.10.7-0.8-0.72.0
One hour access (shock baseline)1.41.62.4-1.4-1.6-1.01.31.2-1.51.41.3-0.5
Number of responses in last shaping day1.01.03.8-0.30.01.2-1.2-0.80.7-0.9-0.02.0
Context. condit. distance diff. score0.70.93.1-1.7-1.30.1-0.20.6-0.70.41.00.9
Locomotion velocity, session 11.21.33.3-0.4-0.3-1.31.41.1-1.11.30.4-1.8
Locomotion distance, session 10.10.20.4-0.4-0.2-0.40.60.4-0.50.60.2-0.3
Locomotion velocity, session 20.91.11.9-0.7-0.5-1.01.31.0-1.21.30.4-1.4
Locomotion distance, session 20.91.21.8-0.6-0.8-1.31.21.2-1.21.11.1-1.2
Locomotion velocity, session 30.10.20.5-0.6-0.50.20.3-0.0-0.10.20.50.7
Locomotion distance, session 30.20.20.5-0.7-0.50.20.4-0.0-0.20.30.60.7
Stereotopy head waving bouts, day 30.40.51.00.71.00.3-0.7-0.50.7-0.6-0.9-0.2
Stereotopy head waving duration, day 30.81.01.51.01.20.8-1.1-0.81.2-1.0-1.20.2
Locomotion velocity, session 70.10.10.4-0.1-0.20.20.1-0.10.1-0.00.10.6
Locomotion distance, session 70.50.61.30.60.40.9-0.5-0.90.9-0.7-0.71.2
Stereotopy head waving bouts, day 70.00.00.10.10.1-0.2-0.40.2-0.0-0.20.3-0.2
Stereotopy head waving duration, day 70.20.20.6-0.3-0.2-0.5-0.30.6-0.50.10.8-0.4
Locomotion velocity, session 80.10.10.6-0.6-0.40.4-0.2-0.1-0.1-0.10.20.8
Locomotion distance, session 80.61.02.6-1.6-1.3-0.40.21.0-1.10.71.20.3
Degree of sensitization distance0.30.30.60.70.40.4-0.5-0.40.6-0.6-0.80.3
Degree of sensitization stereotypy0.10.10.30.1-0.00.1-0.6-0.10.1-0.40.40.4
Condit. Reinf. active minus inactive responses0.20.20.60.1-0.3-0.60.60.5-0.40.40.4-0.8
Condit. Reinf. active-inactive response ratio0.50.61.8-0.2-0.1-0.91.00.6-0.60.90.3-1.3
Condit. Reinf. active responses0.10.10.40.1-0.3-0.2-0.20.2-0.2-0.20.6-0.0
Condit. Reinf. inactive responses0.30.30.8-0.2-0.60.1-0.90.2-0.1-0.60.90.7
Incentive salience index mean0.20.20.50.2-0.3-0.60.70.4-0.30.40.4-0.6
Condit. Reinf. lever presses0.10.10.30.3-0.1-0.40.30.2-0.00.10.2-0.6
Time in familiar zone, hab. session 10.10.10.50.10.20.3-0.7-0.10.3-0.50.10.4
Time in novel zone, hab. session 11.91.83.2-0.8-1.0-1.61.51.4-1.31.51.0-1.8
Total zone transitions, hab. session 10.10.20.5-0.6-0.4-0.10.20.3-0.40.30.70.4
Total locomotion distance, hab. session 10.40.61.5-0.8-0.9-0.41.20.5-0.81.00.60.1
Locomotion velocity, hab. session 10.30.41.3-0.8-0.7-0.01.20.2-0.60.90.40.5
Time in familiar zone, hab. session 21.21.32.31.51.30.9-1.0-1.11.1-1.1-1.40.4
Time in novel zone, hab. session 20.40.40.6-0.8-0.5-0.70.60.6-0.60.70.6-0.7
Total zone transitions, hab. session 20.10.10.20.2-0.0-0.40.40.3-0.20.20.2-0.3
Total locomotion distance, hab. session 20.40.51.4-0.2-0.5-0.81.20.6-0.70.90.4-0.8
Locomotion velocity, hab. session 20.60.81.9-0.6-0.8-0.91.40.8-1.01.20.7-0.7
Novel to familiar place preference ratio0.60.71.2-1.1-1.1-0.70.40.8-0.90.71.1-0.3
Novelty place preference0.40.51.0-1.0-0.9-0.50.20.7-0.70.50.9-0.1
Time in novel zone, NPP test0.80.91.4-1.1-1.1-0.90.61.0-1.00.81.2-0.5
Total zone transitions, NPP test0.10.10.30.50.1-0.30.50.00.00.20.0-0.3
Total locomotion distance, NPP test0.10.20.60.50.3-0.20.8-0.1-0.00.4-0.4-0.6
Locomotion velocity, NPP test0.10.10.50.40.1-0.20.7-0.1-0.10.4-0.2-0.4
Pavlov. Cond. lever latency0.00.00.0-0.20.00.0-0.00.1-0.10.00.10.1
Pavlov. Cond. magazine entry latency0.20.30.80.90.6-0.30.6-0.20.30.2-0.5-0.9
Pavlov. Cond. change in total contacts0.30.31.30.80.3-0.60.40.20.10.2-0.1-1.1
Pavlov. Cond. index score0.20.20.60.80.2-0.30.7-0.10.20.2-0.3-0.6
Pavlov. Cond. latency score0.10.10.40.60.1-0.20.6-0.10.20.2-0.3-0.4
Pavlov. Cond. lever contacts0.20.30.60.1-0.5-0.60.80.4-0.40.50.2-0.7
Pavlov. Cond. magazine entry number0.70.92.8-1.7-1.2-0.10.00.7-0.90.51.20.7
Pavlov. Cond. intertrial magazine entries0.40.41.30.30.10.8-0.7-0.70.6-0.8-0.11.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.5-0.0-0.61.00.2-0.10.5-0.1-0.9
Pavlov. Cond. response bias0.30.41.40.80.3-0.60.80.10.00.3-0.3-1.2
Bone: apparent density4.57.510.22.02.23.2-2.5-3.02.9-2.7-2.63.2
Bone surface4.17.38.62.42.52.9-2.5-2.92.9-2.8-2.62.7
Bone volume4.37.39.12.42.43.0-2.3-3.03.0-2.7-2.62.9
Bone: connectivity density3.65.76.72.12.32.5-2.3-2.62.5-2.5-2.52.1
Bone: cortical apparent density1.41.83.21.81.70.7-1.5-1.11.4-1.4-1.5-0.3
Bone: cortical area1.82.74.61.51.11.9-1.3-1.81.8-1.7-1.22.1
Bone: cortical porosity0.30.30.4-0.6-0.6-0.50.50.6-0.60.60.6-0.3
Bone: cortical porosity0.00.00.1-0.2-0.3-0.20.10.3-0.20.10.3-0.1
Bone: cortical thickness0.10.20.60.8-0.00.30.2-0.50.4-0.3-0.10.6
Bone: cortical thickness0.60.71.71.30.80.6-0.1-0.91.0-0.6-1.00.2
Bone: cortical tissue density1.31.72.91.71.70.6-1.4-1.01.3-1.4-1.4-0.4
Bone: elastic displacement0.60.61.90.81.2-0.2-0.4-0.10.3-0.2-1.2-1.4
Bone: elastic work1.31.73.81.22.00.9-1.4-1.01.1-1.1-1.8-0.3
Bone: endosteal estimation3.57.59.71.92.43.1-2.8-3.02.9-2.9-2.43.0
Bone: endosteal perimeter1.73.45.60.81.52.2-2.0-2.01.9-1.9-1.52.4
Bone: final force0.71.12.31.00.71.2-0.9-1.21.0-1.2-0.61.5
Bone: final moment1.22.12.51.51.31.6-1.1-1.61.5-1.5-1.21.6
Bone: marrow area3.67.710.11.92.53.2-2.9-3.02.9-2.9-2.43.1
Bone: maximum diameter4.17.513.71.42.03.4-2.8-3.02.7-2.8-2.23.7
Bone: maximum force2.34.04.71.91.82.2-1.8-2.22.1-2.1-1.82.1
Bone: maximum moment3.25.66.82.42.32.5-2.0-2.62.5-2.4-2.42.1
Bone: minimum diameter2.24.05.61.41.72.2-2.1-2.12.2-2.2-1.32.4
Bone: periosteal estimation3.97.911.42.12.33.3-2.7-3.13.0-3.0-2.33.4
Bone: periosteal perimeter1.11.85.70.30.61.8-1.2-1.41.2-1.3-0.72.4
Bone: post-yield work0.81.11.81.30.81.0-0.5-1.21.3-1.0-0.71.1
Bone: stiffness0.71.02.80.70.41.1-1.1-1.00.9-1.2-0.21.7
Bone: tissue strength0.10.10.30.60.50.1-0.2-0.30.2-0.3-0.4-0.3
Bone: trabecular number3.55.46.62.12.12.5-2.1-2.62.5-2.4-2.42.3
Bone: trabecular spacing1.41.92.7-0.8-1.3-1.61.41.5-1.31.31.4-1.5
Bone: trabecular thickness3.23.95.21.71.72.2-1.4-2.32.2-1.8-2.22.0
Bone: trabecular tissue density0.60.83.2-0.8-0.31.1-1.1-0.50.3-0.70.11.8
Breakpoint value in progressive ratio session0.20.20.9-0.4-0.50.1-0.30.2-0.1-0.20.80.9
Distance traveled before self-admin0.30.30.4-0.4-0.4-0.50.60.5-0.50.60.5-0.7
Distance traveled after self-admin0.10.20.4-0.5-0.00.6-0.4-0.30.1-0.2-0.30.6
Delta time in closed arm before/after self-admin2.32.25.3-0.1-0.8-2.01.21.6-1.51.21.5-2.3
Delta time in open arm before/after self-admin0.90.83.3-0.70.11.2-1.0-0.70.6-0.6-0.51.8
Diff in mean of infusions in LGA sessions4.55.16.3-2.4-1.9-2.31.92.5-2.32.32.4-2.3
Extinction: sum of active levers before priming0.10.10.60.2-0.2-0.1-0.70.20.1-0.50.30.0
Active lever presses in extinction session 60.40.42.0-0.8-0.40.4-0.40.1-0.1-0.20.71.4
Delta distance traveled before/after self-admin0.60.61.9-0.40.31.0-0.9-0.60.5-0.6-0.61.4
Delta ambulatory time before/after self-admin1.41.53.60.00.71.6-1.5-1.11.0-1.2-1.01.9
Time in closed arm before self-admin0.20.30.9-0.9-0.5-0.10.80.3-0.40.70.00.1
Time in closed arm after self-admin1.61.73.4-0.4-0.7-1.51.81.2-1.01.50.7-1.8
Time in open arm before self-admin0.40.52.20.50.2-0.90.60.5-0.40.40.2-1.5
Time in open arm after self-admin0.10.10.7-0.5-0.20.3-0.4-0.0-0.0-0.20.20.8
Sum of active levers in priming session hrs 5-60.30.31.3-0.20.0-0.70.30.6-0.30.40.3-1.1
Time to tail flick, vehicle, before self-admin0.00.00.2-0.20.3-0.0-0.00.0-0.10.1-0.1-0.4
Time to tail flick, vehicle, after self-admin0.20.20.60.80.10.2-0.0-0.40.5-0.4-0.20.4
Time to tail flick, test, before self-admin0.40.40.9-0.1-0.11.0-0.5-0.70.7-0.5-0.70.8
Time to tail flick, test, after self-admin0.30.30.70.90.40.5-0.2-0.80.7-0.5-0.70.0
Delta time to tail flick, vehicle, before/after SA0.20.21.10.1-0.70.30.1-0.30.3-0.20.21.1
Delta time to tail flick, test, before/after SA0.20.20.4-0.2-0.3-0.40.60.3-0.50.50.6-0.1
Ambulatory time before self-admin0.40.40.5-0.4-0.5-0.70.70.6-0.70.70.5-0.7
Ambulatory time after self-admin0.30.31.5-1.2-0.40.5-0.2-0.0-0.30.20.20.7
Total heroin consumption1.61.94.6-1.4-2.1-1.00.91.2-1.31.02.10.0
Area under the delay curve2.83.06.62.61.51.5-1.3-1.81.9-1.8-1.80.8
Delay disc. indifference point, 0s delay0.90.92.60.80.31.2-0.9-1.00.8-1.1-0.41.6
Delay disc. indifference point, 16s delay4.95.07.52.71.92.1-1.5-2.42.5-2.2-2.51.7
Delay disc. indifference point, 2s delay2.73.05.02.21.81.5-1.3-1.82.0-1.7-2.00.9
Delay disc. indifference point, 24s delay4.84.66.92.61.92.1-1.7-2.42.4-2.3-2.11.7
Delay disc. indifference point, 4s delay0.30.31.00.5-0.30.6-0.4-0.50.4-0.60.01.0
Delay disc. indifference point, 8s delay2.22.37.02.61.50.9-0.5-1.51.5-1.3-1.9-0.2
Delay discount exponential model param2.83.06.7-2.6-1.5-1.51.21.8-1.91.81.8-0.8
Delay discount hyperbolic model param2.83.06.5-2.5-1.5-1.51.31.8-1.91.81.8-0.8
Fecal boli incidents, locomotor time 10.20.20.7-0.3-0.10.80.1-0.60.3-0.0-0.50.8
Change in fecal boli incidents, locomotor task0.90.91.6-0.7-1.1-1.20.21.1-1.00.51.3-0.9
Time >=10cm from walls, locomotor time 10.50.52.4-0.6-0.30.7-0.5-0.40.3-0.40.31.5
Bouts of movement, locomotor time 11.21.43.3-1.2-1.2-0.91.80.9-1.11.51.0-0.3
Total resting periods, locomotor time 10.60.72.1-0.9-1.0-0.21.40.3-0.61.00.70.5
Rest time, locomotor task time 10.80.82.1-1.4-1.2-0.11.00.5-1.01.10.50.3
Distance moved, locomotor task time 10.20.20.80.60.3-0.80.10.30.00.00.4-0.9
Vertical activity count, locomotor time 10.30.31.20.20.2-0.90.20.6-0.30.30.4-1.1
Time >=10cm from walls, locomotor time 20.20.20.50.40.40.3-0.7-0.30.6-0.7-0.20.5
Bouts of movement, locomotor time 20.30.31.2-0.0-0.8-0.31.10.2-0.40.70.0-0.2
Total resting periods, locomotor time 20.30.31.30.0-0.9-0.31.10.2-0.50.70.0-0.2
Rest time, locomotor task time 21.41.64.1-1.4-2.0-0.81.21.1-1.41.21.3-0.1
Distance moved, locomotor task time 20.20.21.00.20.6-0.7-0.00.40.00.10.1-1.0
Vertical activity count, locomotor time 20.30.31.50.50.7-0.6-0.10.30.10.0-0.3-1.2
Weight adjusted by age0.00.00.1-0.10.10.00.10.1-0.20.1-0.30.0
Seeking ratio, delayed vs. immediate footshock0.60.71.9-1.4-0.6-0.60.31.0-1.00.70.90.0
Locomotion in novel chamber0.40.51.3-0.50.70.8-1.1-0.40.3-0.6-0.31.0
Locomotion in novel chamber post-restriction2.02.34.7-2.2-2.1-1.00.81.5-1.61.22.0-0.1
Progressive ratio0.10.10.2-0.2-0.2-0.30.10.3-0.30.10.40.1
Food seeking constrained by brief footshock2.32.84.5-2.1-1.9-1.41.81.6-1.51.91.7-0.8
Seeking ratio, punishment vs. effort1.11.32.2-1.1-1.2-1.01.51.0-0.91.40.8-1.1
Run reversals in cocaine runway, females0.20.20.20.30.40.4-0.5-0.40.3-0.4-0.50.0
Run reversals in cocaine runway, males2.72.64.8-1.4-1.9-1.42.21.4-1.61.91.3-1.1
Latency to leave start box in cocaine runway0.30.31.6-1.3-0.6-0.20.00.5-0.40.50.30.1
Latency to leave start box in cocaine runway, F1.61.83.5-1.9-1.4-1.21.01.4-1.41.51.0-1.0
Latency to leave start box in cocaine runway, M0.20.20.30.20.50.4-0.3-0.40.5-0.4-0.50.5
Cd content in liver0.70.82.61.61.00.3-0.2-0.81.0-0.7-1.0-0.3
Co content in liver0.20.21.0-0.20.1-0.50.10.4-0.40.30.1-1.0
Cu content in liver0.80.92.80.2-0.3-1.11.50.6-0.71.1-0.2-1.7
Fe content in liver3.74.47.6-1.1-1.4-2.52.32.1-2.22.31.7-2.8
K content in liver0.60.61.2-1.1-0.9-0.60.60.9-1.00.80.7-0.3
Mg content in liver1.31.31.6-1.1-1.2-1.11.11.2-1.31.21.0-1.0
Mn content in liver4.65.36.2-2.2-2.2-2.42.12.5-2.52.32.4-1.8
Na content in liver3.84.05.0-2.2-2.1-1.91.82.2-2.22.12.0-1.3
Rb content in liver0.70.91.9-1.1-1.1-0.90.31.1-0.90.61.4-0.2
Se content in liver11.113.527.2-1.4-2.6-4.63.64.0-3.73.62.9-5.2
Sr content in liver0.10.10.5-0.10.20.30.1-0.30.10.1-0.7-0.1
Zn content in liver2.42.66.0-0.7-0.8-2.01.71.7-1.71.71.0-2.5