Hub : Genes

Tecpr2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021904 0.03 0.02 2.1e-03 0.01 0.01 0.01 0.01 1.0e-02 1.7e-02 3.5e-02 3.6e-02
2 Adipose mRNA stability ENSRNOG00000021904 0.16 0.12 1.4e-09 0.07 0.07 0.07 0.07 2.6e-08 1.3e-08 3.9e-08 5.0e-08
3 BLA gene expression ENSRNOG00000021904 0.26 0.26 9.9e-10 0.21 0.18 0.16 0.19 1.5e-11 7.5e-10 7.8e-09 1.2e-10
4 BLA mRNA stability ENSRNOG00000021904 0.15 0.11 6.4e-03 0.03 0.04 0.02 0.02 1.6e-02 3.6e-03 3.8e-02 3.4e-02
5 Eye gene expression ENSRNOG00000021904 0.39 0.21 1.6e-03 0.11 0.13 0.11 0.13 9.0e-03 5.2e-03 1.1e-02 5.1e-03
6 IL mRNA stability ENSRNOG00000021904 0.16 0.19 8.7e-03 0.08 0.06 0.05 0.04 6.3e-03 1.6e-02 2.3e-02 3.4e-02
7 NAcc gene expression ENSRNOG00000021904 0.18 0.11 1.9e-09 0.12 0.12 0.1 0.11 3.5e-09 7.0e-09 5.8e-08 1.5e-08
8 NAcc mRNA stability ENSRNOG00000021904 0.1 0.08 2.4e-05 0.07 0.06 0.04 0.07 3.1e-06 3.0e-05 9.6e-04 8.5e-06
9 OFC gene expression ENSRNOG00000021904 0.12 0.1 9.0e-03 0.08 0.06 0.08 0.06 7.1e-03 1.7e-02 6.4e-03 1.8e-02
10 PL gene expression ENSRNOG00000021904 0.1 0.07 3.0e-09 0.11 0.11 0.1 0.1 1.9e-08 1.0e-08 6.2e-08 4.0e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.31.06.0-0.50.4-0.41.3-0.8-0.5-0.4-0.4-2.5-0.9
BMI without tail0.91.85.71.01.81.22.41.11.21.21.2-0.50.9
Body weight0.72.94.41.81.91.72.11.61.61.71.70.81.6
Epididymis fat weight2.96.910.2-2.7-2.2-2.6-1.5-2.7-2.8-2.6-2.6-3.2-2.8
Glucose0.10.10.60.4-0.30.0-0.80.00.20.00.00.60.2
Heart weight0.00.00.2-0.0-0.0-0.1-0.0-0.5-0.1-0.1-0.10.2-0.1
Left kidney weight0.61.82.11.51.31.41.21.31.31.41.41.41.4
Right kidney weight0.30.81.11.10.90.90.81.00.90.90.90.71.0
Tail length2.98.710.53.12.62.92.13.23.12.92.93.13.1
Length with tail2.28.113.43.02.32.81.53.12.82.82.83.73.1
Length without tail0.30.62.50.80.20.6-0.20.70.50.60.61.60.8
Liver weight, left4.97.99.93.12.62.82.33.02.92.82.82.82.9
Liver weight, right0.10.20.40.70.50.40.50.50.30.40.40.20.3
Parametrial fat weight0.51.01.80.81.21.01.30.91.01.01.00.70.9
Retroperitoneal fat weight0.00.10.60.20.40.20.80.00.10.20.2-0.40.1
Intraocular pressure0.10.20.4-0.7-0.4-0.3-0.4-0.6-0.5-0.3-0.3-0.2-0.4
Extensor digitorum longus weight5.722.925.44.84.55.03.74.94.95.05.04.95.0
Soleus weight0.00.10.2-0.4-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.5-0.3
Tibialis anterior weight0.51.82.11.31.41.41.31.41.31.41.41.21.4
Tibia length0.10.41.30.40.40.60.00.60.60.60.61.20.8
Number of licking bursts1.01.21.71.31.21.11.31.01.11.11.10.61.0
Food consumed during 24 hour testing period0.30.30.40.50.60.60.50.50.60.60.60.60.6
Times rat made contact with spout0.00.00.20.1-0.10.0-0.40.10.00.00.00.40.1
Mean time between licks in bursts0.40.60.9-0.9-0.5-0.7-0.3-1.0-0.7-0.7-0.7-0.9-0.8
Mean num. licks in bursts1.11.32.5-1.3-1.3-1.1-1.6-1.0-1.1-1.1-1.1-0.4-1.0
Std. dev. time between licks in bursts1.51.82.1-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.0-1.3
Water consumed over 24 hours2.12.53.51.71.41.61.01.71.61.61.61.91.7
Indifference point 0 sec1.32.03.41.21.21.50.81.61.41.51.51.81.7
Indifference point AUC3.03.64.41.91.81.81.72.12.01.81.81.91.9
Indifference point function ln k0.10.10.30.2-0.10.1-0.50.00.20.10.10.50.3
Indifference point function log k0.10.10.30.2-0.10.1-0.50.00.20.10.10.50.3
Delay discounting total patch changes 0 sec1.42.33.71.41.31.60.81.61.41.61.61.91.7
Delay discounting total patch changes 12 sec2.53.34.31.71.81.91.52.11.91.91.91.72.0
Delay discounting total patch changes 18 sec0.30.40.60.50.50.60.40.70.70.60.60.80.7
Delay discounting total patch changes 24 sec0.81.02.20.71.20.91.51.11.00.90.90.61.0
Delay discounting total patch changes 6 sec3.24.95.62.22.32.32.32.42.32.32.31.62.2
Delay discounting time to switch 0 sec7.411.216.9-3.5-2.9-3.4-2.1-3.4-3.4-3.4-3.4-4.1-3.6
Delay discounting water rate 0 sec12.620.127.74.53.94.72.84.54.64.74.75.34.8
Delay discounting water rate 12 sec11.116.620.34.53.94.23.34.14.24.24.24.14.2
Delay discounting water rate 18 sec3.04.07.22.11.62.10.92.11.92.12.12.72.2
Delay discounting water rate 24 sec3.44.75.52.21.92.31.32.22.22.32.32.32.3
Delay discounting water rate 6 sec2.63.86.42.01.62.01.01.82.02.02.02.52.1
Locomotor activity0.00.00.1-0.3-0.2-0.2-0.3-0.30.0-0.2-0.20.1-0.0
Locomotor testing distance0.10.20.8-0.5-0.6-0.3-0.9-0.4-0.2-0.3-0.30.2-0.2
Locomotor testing rearing2.64.15.6-2.4-1.9-2.0-1.7-2.2-2.0-2.0-2.0-1.9-2.0
Light reinforcement 10.00.00.1-0.3-0.0-0.00.0-0.2-0.1-0.0-0.0-0.3-0.1
Light reinforcement 21.62.12.4-1.6-1.5-1.4-1.4-1.5-1.5-1.4-1.4-1.2-1.5
Reaction time number correct0.91.32.81.50.81.10.31.11.21.11.11.71.2
Reaction time mean minus median0.20.31.10.20.80.51.00.50.50.50.50.00.5
Reaction time mean minus median AUC0.10.10.5-0.10.50.30.70.40.40.30.3-0.00.3
Reaction time num false alarms0.20.20.50.70.20.4-0.00.70.30.40.40.60.5
Reaction time num false alarms AUC0.40.61.10.90.40.70.11.00.50.70.71.00.8
Reaction time trials correct on left0.91.32.81.50.81.10.31.11.21.11.11.71.2
Reaction time trials on left1.01.42.81.50.91.10.41.11.31.11.11.71.3
Reaction time mean0.10.10.6-0.40.30.00.8-0.0-0.20.00.0-0.7-0.1
Reaction time mean AUC0.10.10.7-0.30.40.20.80.10.00.20.2-0.40.0
Median of all reaction times0.10.10.3-0.40.2-0.00.6-0.1-0.2-0.0-0.0-0.6-0.2
Reaction time omissions2.93.94.61.92.12.02.12.22.02.02.01.51.9
Reaction time false alarm rate0.10.10.30.30.20.30.10.60.10.30.30.30.3
Reaction time premature initiation rate0.60.81.10.91.00.90.90.91.00.90.90.71.0
Reaction time premature initiations1.11.52.01.41.11.20.81.21.31.21.21.41.4
Std. dev. reaction times0.30.51.80.20.90.61.30.70.50.60.6-0.10.5
Reaction time trials completed1.01.42.81.50.91.10.41.11.31.11.11.71.3
Reaction time trials AUC1.21.73.11.61.01.20.51.21.41.21.21.81.4
Social response proportion0.91.01.40.81.11.01.20.81.11.01.00.90.9
Social responses0.10.10.5-0.7-0.3-0.3-0.3-0.5-0.4-0.3-0.3-0.1-0.3
Social time1.01.31.71.11.11.10.91.31.31.11.11.01.2
Conditioned locomotion0.20.20.70.10.10.4-0.20.60.20.40.40.80.5
Cocaine response after cond. corrected0.10.10.3-0.1-0.2-0.30.0-0.3-0.3-0.3-0.3-0.6-0.4
Cocaine response after cond. not corrected0.60.61.5-0.5-0.5-0.8-0.1-0.9-0.8-0.8-0.8-1.2-0.9
Cocaine response before conditioning1.82.33.3-1.5-1.3-1.5-0.9-1.6-1.5-1.5-1.5-1.8-1.6
Saline control response1.82.43.9-1.5-1.8-1.5-2.0-1.4-1.5-1.5-1.5-1.0-1.4
Condit. Reinf. active minus inactive responses1.01.21.61.21.21.11.30.91.11.11.10.91.0
Condit. Reinf. active-inactive response ratio0.60.60.80.90.80.80.70.70.80.80.80.80.7
Condit. Reinf. active responses0.20.30.90.60.70.50.90.30.50.50.50.10.4
Condit. Reinf. inactive responses0.30.40.7-0.6-0.5-0.6-0.3-0.7-0.6-0.6-0.6-0.8-0.7
Condit. Reinf. lever presses0.50.71.7-0.9-0.5-0.8-0.0-1.1-0.8-0.8-0.8-1.3-1.0
Condit. Reinf. lever reinforcers received0.20.30.80.50.70.50.90.30.50.50.50.10.4
Pavlov. Cond. lever latency1.31.72.51.41.11.30.71.51.31.31.31.61.4
Pavlov. Cond. magazine entry latency3.44.05.7-2.0-1.7-2.0-1.2-2.1-2.1-2.0-2.0-2.4-2.1
Pavlov. Cond. change in total contacts2.94.05.3-1.9-1.7-2.1-1.2-2.2-2.1-2.1-2.1-2.3-2.2
Pavlov. Cond. index score3.04.06.1-1.9-1.6-2.0-1.0-2.2-2.1-2.0-2.0-2.5-2.2
Pavlov. Cond. latency score3.03.85.8-1.9-1.6-2.0-1.0-2.2-2.0-2.0-2.0-2.4-2.1
Pavlov. Cond. lever contacts0.91.32.8-1.1-0.7-1.1-0.1-1.4-1.1-1.1-1.1-1.7-1.3
Pavlov. Cond. magazine entry number2.22.74.71.71.31.60.71.91.71.61.62.21.8
Pavlov. Cond. intertrial magazine entries1.51.94.01.50.91.30.21.61.31.31.32.01.5
Pavlov. Cond. lever-magazine prob. diff.3.95.07.2-2.2-1.9-2.3-1.3-2.5-2.3-2.3-2.3-2.7-2.4
Pavlov. Cond. response bias1.62.24.4-1.4-1.0-1.4-0.3-1.7-1.5-1.4-1.4-2.1-1.6
Conditioned reinforcement - actives0.50.51.40.60.40.70.00.80.70.70.71.20.8
Conditioned reinforcement - inactives0.10.10.30.20.20.3-0.00.30.30.30.30.50.3
Conditioned locomotion1.51.92.6-1.6-1.4-1.4-1.3-1.4-1.3-1.4-1.4-0.8-1.4
Intermittent access intake day 1-15 change2.82.83.2-1.5-1.8-1.7-1.7-1.7-1.6-1.7-1.7-1.4-1.7
Intermittent access intake escalation3.13.13.5-1.6-1.9-1.8-1.8-1.8-1.7-1.8-1.8-1.5-1.8
Intermittent access intake escalation 20.70.71.1-0.7-1.0-0.8-1.1-0.8-0.7-0.8-0.8-0.5-0.8
Intermitt. access day 1 inactive lever presses1.01.11.81.10.81.00.31.11.11.01.01.41.2
Intermitt. access day 15 inactive lever presses0.10.10.20.40.10.4-0.20.50.40.40.40.10.5
Intermitt. access escalation Index2.22.02.91.61.61.41.71.21.41.41.41.01.3
Intermittent access day 1 total infusions0.10.10.3-0.30.2-0.00.5-0.1-0.1-0.0-0.0-0.4-0.1
Intermittent access day 15 total infusions1.21.31.7-1.2-1.0-1.2-0.6-1.2-1.2-1.2-1.2-1.3-1.3
Intermittent access terminal intake (last 3 days)1.21.41.8-1.3-0.9-1.2-0.5-1.3-1.2-1.2-1.2-1.3-1.3
Intermittent access total infusions0.40.40.7-0.8-0.5-0.7-0.2-0.6-0.7-0.7-0.7-0.9-0.7
Intermittent access day 1 locomotion0.50.50.9-0.9-0.5-0.7-0.2-0.8-0.8-0.7-0.7-0.5-0.8
Intermittent access day 15 total locomotion0.30.30.6-0.7-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.4-0.6
Intermittent access total locomotion0.50.60.8-0.9-0.7-0.8-0.5-0.8-0.8-0.8-0.8-0.6-0.8
Intermittent access standard deviation3.74.04.7-1.9-1.9-2.1-1.6-2.2-2.0-2.1-2.1-1.8-2.1
Cocaine induced anxiety3.03.44.41.81.71.91.42.11.91.91.91.91.9
Post-drug Anxiety2.42.73.41.51.51.71.21.91.71.71.71.71.7
Baseline Anxiety1.41.41.7-1.2-1.1-1.2-0.9-1.3-1.2-1.2-1.2-1.3-1.3
Lifetime Intake0.30.30.6-0.8-0.5-0.6-0.2-0.5-0.6-0.6-0.6-0.5-0.6
Incentive Sensitization - Responses0.10.10.40.20.50.40.60.30.40.40.4-0.30.3
Incentive Sensitization - Breakpoint0.20.20.40.30.50.40.60.30.40.40.4-0.10.4
Progressive ratio test 1 active lever presses0.10.10.3-0.5-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.1-0.4
Progressive ratio test 1 breakpoint0.20.20.4-0.7-0.5-0.5-0.4-0.6-0.5-0.5-0.5-0.3-0.5
Progressive ratio test 1 inactive lever presses0.60.71.50.80.50.9-0.00.80.90.90.91.21.0
Progressive ratio test 2 active lever presses0.00.00.0-0.20.10.00.2-0.0-0.00.00.0-0.20.0
Progressive ratio test 2 breakpoint0.00.00.0-0.20.10.00.2-0.0-0.00.00.0-0.20.0
Progressive ratio test 2 inactive lever presses0.60.70.90.80.90.90.70.90.90.90.90.70.9
Total sessions with >9 infusions0.70.81.0-1.0-1.0-0.9-0.9-0.8-0.9-0.9-0.90.2-0.9
Short access day 1 total inactive lever presses0.10.10.3-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.6-0.3
Short access day 10 total inactive lever presses0.60.70.90.90.90.90.80.80.90.90.90.40.9
Short access day 1 total infusions0.10.10.20.40.30.30.20.40.40.30.30.50.3
Short access day 10 total infusions0.50.50.9-0.9-0.6-0.7-0.5-0.8-0.7-0.7-0.7-0.6-0.8
Short access total infusions0.30.30.5-0.7-0.5-0.6-0.3-0.5-0.5-0.6-0.6-0.4-0.6
Short access day 1 locomotion1.11.21.5-1.2-1.1-1.2-0.9-1.1-1.1-1.2-1.2-0.7-1.1
Short access day 10 total locomotion0.70.71.1-0.9-0.8-0.9-0.6-1.1-0.8-0.9-0.9-0.6-0.9
Short access total locomotion0.20.20.3-0.6-0.4-0.5-0.4-0.5-0.5-0.5-0.50.1-0.5
Compulsive drug intake0.00.00.10.10.10.10.20.10.10.10.1-0.30.1
One hour access (0.3 mA shock)0.00.00.1-0.10.00.10.00.10.10.10.10.30.1
One hour access (shock baseline)0.20.20.3-0.5-0.5-0.5-0.5-0.4-0.4-0.5-0.50.0-0.4
Number of responses in last shaping day0.10.10.4-0.10.40.20.60.00.20.20.2-0.20.1
Context. condit. distance diff. score0.30.41.30.50.20.5-0.20.50.60.50.51.10.7
Locomotion velocity, session 10.40.40.70.40.60.60.50.50.70.60.60.80.7
Locomotion distance, session 10.10.10.2-0.2-0.1-0.40.1-0.4-0.3-0.4-0.4-0.3-0.3
Locomotion velocity, session 20.00.00.0-0.1-0.0-0.20.1-0.1-0.1-0.2-0.2-0.2-0.1
Locomotion distance, session 20.10.20.3-0.1-0.4-0.6-0.2-0.5-0.5-0.6-0.6-0.4-0.5
Locomotion velocity, session 31.82.12.9-1.4-1.6-1.5-1.7-1.4-1.4-1.5-1.5-0.9-1.4
Locomotion distance, session 30.60.61.6-0.8-1.0-0.7-1.3-0.7-0.7-0.7-0.7-0.2-0.6
Stereotopy head waving bouts, day 30.10.10.20.40.40.40.30.30.40.40.40.40.4
Stereotopy head waving duration, day 30.20.20.30.50.50.50.50.50.50.50.50.50.5
Locomotion velocity, session 73.84.25.7-2.1-2.3-2.1-2.4-1.8-2.0-2.1-2.1-1.3-1.9
Locomotion distance, session 72.93.74.2-2.0-2.0-2.0-2.0-1.8-1.9-2.0-2.0-1.5-1.8
Stereotopy head waving bouts, day 70.10.10.4-0.0-0.10.2-0.50.20.10.20.20.70.3
Stereotopy head waving duration, day 70.10.10.20.10.10.3-0.00.20.20.30.30.40.3
Locomotion velocity, session 80.00.00.10.0-0.10.0-0.2-0.10.00.00.00.20.1
Locomotion distance, session 80.40.61.1-0.7-0.9-0.8-1.0-0.9-0.8-0.8-0.8-0.3-0.7
Degree of sensitization distance0.20.20.3-0.5-0.4-0.5-0.3-0.3-0.5-0.5-0.5-0.5-0.5
Degree of sensitization stereotypy0.10.10.6-0.4-0.5-0.2-0.7-0.3-0.3-0.2-0.20.2-0.2
Condit. Reinf. active minus inactive responses0.40.40.5-0.4-0.6-0.7-0.5-0.7-0.7-0.7-0.7-0.7-0.7
Condit. Reinf. active-inactive response ratio1.51.72.5-1.2-1.1-1.3-0.8-1.6-1.3-1.3-1.3-1.5-1.4
Condit. Reinf. active responses0.40.40.5-0.4-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.7
Condit. Reinf. inactive responses0.91.11.81.10.81.00.51.21.01.01.01.41.1
Incentive salience index mean0.40.50.6-0.4-0.7-0.7-0.6-0.7-0.8-0.7-0.7-0.7-0.8
Condit. Reinf. lever presses0.40.50.6-0.4-0.8-0.8-0.8-0.6-0.8-0.8-0.8-0.5-0.8
Time in familiar zone, hab. session 12.22.12.3-1.1-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.5
Time in novel zone, hab. session 10.80.81.60.51.10.91.30.80.90.90.90.60.8
Total zone transitions, hab. session 10.81.21.4-0.7-1.1-1.1-1.1-1.0-1.2-1.1-1.1-0.9-1.1
Total locomotion distance, hab. session 10.10.10.3-0.1-0.4-0.3-0.5-0.1-0.3-0.3-0.3-0.1-0.2
Locomotion velocity, hab. session 10.10.10.20.4-0.10.2-0.30.40.10.20.20.50.3
Time in familiar zone, hab. session 21.81.82.3-1.4-1.4-1.3-1.3-1.5-1.3-1.3-1.3-1.3-1.4
Time in novel zone, hab. session 21.31.32.61.11.41.11.61.01.11.11.10.71.1
Total zone transitions, hab. session 20.30.40.5-0.5-0.5-0.7-0.4-0.7-0.7-0.7-0.7-0.7-0.7
Total locomotion distance, hab. session 20.40.50.70.60.60.70.40.80.70.70.70.80.8
Locomotion velocity, hab. session 20.20.30.60.60.30.50.00.70.50.50.50.80.6
Novel to familiar place preference ratio0.00.00.2-0.5-0.1-0.20.0-0.3-0.2-0.2-0.2-0.2-0.2
Novelty place preference0.00.00.1-0.40.10.00.2-0.2-0.00.00.0-0.1-0.0
Time in novel zone, NPP test0.00.00.1-0.30.10.00.2-0.2-0.00.00.0-0.0-0.0
Total zone transitions, NPP test0.00.00.20.30.30.10.40.10.10.10.1-0.10.1
Total locomotion distance, NPP test0.00.00.10.0-0.00.1-0.20.10.10.10.10.30.2
Locomotion velocity, NPP test0.00.10.20.20.10.2-0.00.20.20.20.20.40.3
Pavlov. Cond. lever latency0.20.30.80.40.40.50.20.40.70.50.50.90.6
Pavlov. Cond. magazine entry latency1.92.53.3-1.5-1.8-1.6-1.8-1.4-1.7-1.6-1.6-1.3-1.6
Pavlov. Cond. change in total contacts0.30.30.5-0.5-0.5-0.5-0.3-0.5-0.7-0.5-0.5-0.7-0.6
Pavlov. Cond. index score0.70.91.3-0.9-0.9-0.9-0.7-0.8-1.1-0.9-0.9-1.1-1.0
Pavlov. Cond. latency score0.30.40.7-0.5-0.5-0.6-0.4-0.5-0.7-0.6-0.6-0.8-0.7
Pavlov. Cond. lever contacts0.40.51.0-0.6-0.6-0.7-0.4-0.5-0.8-0.7-0.7-1.0-0.8
Pavlov. Cond. magazine entry number1.31.61.91.31.31.31.11.21.41.31.31.41.4
Pavlov. Cond. intertrial magazine entries2.42.95.21.91.31.70.71.81.71.71.72.31.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.1-0.9-0.9-0.9-0.8-0.7-1.0-0.9-0.9-1.0-1.0
Pavlov. Cond. response bias2.22.83.2-1.6-1.7-1.7-1.6-1.5-1.8-1.7-1.7-1.6-1.7
Bone: apparent density0.50.91.5-0.9-1.1-0.9-1.2-1.2-0.9-0.9-0.9-0.5-0.8
Bone surface0.00.00.2-0.4-0.1-0.1-0.1-0.4-0.0-0.1-0.1-0.1-0.1
Bone volume0.20.40.7-0.7-0.7-0.6-0.8-0.8-0.5-0.6-0.6-0.3-0.6
Bone: connectivity density0.00.00.0-0.20.00.1-0.1-0.20.10.10.10.20.1
Bone: cortical apparent density4.96.39.62.62.12.61.42.62.72.62.63.12.7
Bone: cortical area0.20.31.50.3-0.10.4-0.70.20.40.40.41.20.6
Bone: cortical porosity1.21.22.7-1.0-1.3-1.1-1.6-1.1-1.0-1.1-1.1-0.6-1.0
Bone: cortical porosity1.71.82.9-1.2-1.5-1.3-1.7-1.4-1.3-1.3-1.3-0.9-1.3
Bone: cortical thickness0.20.32.0-0.1-0.7-0.1-1.4-0.1-0.1-0.1-0.11.00.1
Bone: cortical thickness0.30.42.10.0-0.8-0.3-1.5-0.3-0.2-0.3-0.30.6-0.1
Bone: cortical tissue density5.57.210.12.72.32.71.62.72.92.72.73.22.9
Bone: elastic displacement0.10.10.70.2-0.4-0.1-0.8-0.10.0-0.1-0.10.50.1
Bone: elastic work0.10.10.70.1-0.5-0.2-0.8-0.3-0.1-0.2-0.20.3-0.1
Bone: endosteal estimation0.10.31.30.20.80.41.10.30.50.40.4-0.10.3
Bone: endosteal perimeter0.51.02.10.61.21.11.50.90.81.11.10.61.0
Bone: final force0.10.20.9-0.3-0.5-0.1-0.9-0.3-0.1-0.1-0.10.70.0
Bone: final moment0.10.20.9-0.2-0.4-0.1-0.9-0.3-0.0-0.1-0.10.70.1
Bone: marrow area0.10.31.20.20.80.51.10.30.50.50.5-0.10.3
Bone: maximum diameter0.40.71.00.80.90.90.90.51.00.90.90.80.9
Bone: maximum force0.10.21.0-0.4-0.5-0.1-1.0-0.3-0.1-0.1-0.10.60.0
Bone: maximum moment0.10.21.1-0.4-0.6-0.1-1.0-0.3-0.1-0.1-0.10.6-0.0
Bone: minimum diameter0.40.71.20.70.70.90.40.70.90.90.91.10.9
Bone: periosteal estimation0.30.70.90.60.90.90.80.60.90.90.90.90.9
Bone: periosteal perimeter0.40.70.90.40.91.00.90.80.71.01.00.80.9
Bone: post-yield work0.50.71.50.50.60.90.30.90.80.90.91.20.9
Bone: stiffness0.50.72.50.50.40.9-0.20.70.80.90.91.61.0
Bone: tissue strength0.00.00.3-0.2-0.3-0.1-0.50.1-0.1-0.1-0.10.20.1
Bone: trabecular number0.10.20.4-0.4-0.5-0.3-0.7-0.6-0.4-0.3-0.3-0.1-0.3
Bone: trabecular spacing0.00.00.10.30.0-0.00.00.20.1-0.0-0.00.10.0
Bone: trabecular thickness0.00.10.10.40.20.20.00.10.30.20.20.20.2
Bone: trabecular tissue density0.00.00.0-0.0-0.1-0.0-0.20.0-0.0-0.0-0.00.20.1
Breakpoint value in progressive ratio session0.00.00.1-0.4-0.1-0.2-0.10.0-0.2-0.2-0.2-0.0-0.1
Distance traveled before self-admin0.30.30.70.50.70.50.80.40.50.50.5-0.10.4
Distance traveled after self-admin0.20.20.60.80.30.3-0.00.30.60.30.30.60.5
Delta time in closed arm before/after self-admin0.00.00.1-0.2-0.1-0.1-0.00.0-0.2-0.1-0.1-0.3-0.1
Delta time in open arm before/after self-admin1.31.31.51.11.21.21.21.11.21.21.20.81.1
Diff in mean of infusions in LGA sessions0.30.30.9-0.6-0.8-0.5-0.9-0.5-0.6-0.5-0.50.1-0.5
Extinction: sum of active levers before priming0.00.00.1-0.30.00.10.10.1-0.10.10.10.1-0.0
Active lever presses in extinction session 61.11.11.90.90.91.10.61.00.91.11.11.41.1
Delta distance traveled before/after self-admin1.21.23.0-0.8-1.4-1.1-1.7-1.0-0.9-1.1-1.1-0.3-0.9
Delta ambulatory time before/after self-admin0.40.41.6-0.2-0.8-0.7-1.3-0.5-0.2-0.7-0.70.4-0.3
Time in closed arm before self-admin1.51.82.4-1.3-1.0-1.5-0.6-1.5-1.2-1.5-1.5-1.4-1.4
Time in closed arm after self-admin0.80.81.4-1.0-0.7-0.9-0.4-0.9-0.9-0.9-0.9-1.2-1.0
Time in open arm before self-admin3.94.15.22.21.82.11.42.12.02.12.12.32.1
Time in open arm after self-admin3.53.94.42.01.92.11.61.92.02.12.11.92.0
Sum of active levers in priming session hrs 5-60.90.91.1-1.0-1.0-1.0-1.1-1.0-0.9-1.0-1.0-0.8-0.9
Time to tail flick, vehicle, before self-admin0.90.91.11.00.90.80.81.01.00.80.80.91.0
Time to tail flick, vehicle, after self-admin0.70.81.0-1.0-1.0-1.0-0.9-0.8-0.8-1.0-1.0-0.6-0.9
Time to tail flick, test, before self-admin0.10.10.20.00.20.40.20.2-0.00.40.40.30.2
Time to tail flick, test, after self-admin1.21.31.71.11.01.20.71.31.01.21.21.31.2
Delta time to tail flick, vehicle, before/after SA1.21.21.8-1.2-1.3-1.0-1.3-1.1-1.1-1.0-1.0-0.5-1.1
Delta time to tail flick, test, before/after SA0.60.50.80.80.60.60.30.90.80.60.60.80.9
Ambulatory time before self-admin0.30.41.00.40.80.61.00.50.40.60.6-0.10.4
Ambulatory time after self-admin0.20.20.4-0.1-0.4-0.6-0.6-0.5-0.1-0.6-0.6-0.2-0.3
Total heroin consumption0.60.71.40.60.61.00.30.90.81.01.01.20.9
Area under the delay curve0.50.51.60.41.00.71.30.50.60.70.70.00.5
Delay disc. indifference point, 0s delay0.10.10.30.50.40.30.40.30.30.30.30.20.3
Delay disc. indifference point, 16s delay0.60.61.70.51.00.91.30.60.60.90.9-0.10.6
Delay disc. indifference point, 2s delay0.10.10.30.30.50.30.60.20.40.30.3-0.00.2
Delay disc. indifference point, 24s delay0.80.81.60.51.01.11.20.80.71.11.10.20.8
Delay disc. indifference point, 4s delay0.91.01.80.91.21.01.40.81.01.01.00.50.9
Delay disc. indifference point, 8s delay0.30.31.40.20.80.41.20.30.40.40.4-0.10.3
Delay discount exponential model param0.60.71.9-0.5-1.1-0.8-1.4-0.6-0.7-0.8-0.8-0.1-0.7
Delay discount hyperbolic model param0.50.51.5-0.4-1.0-0.7-1.2-0.5-0.6-0.7-0.7-0.1-0.5
Fecal boli incidents, locomotor time 10.20.21.00.00.50.21.00.00.10.20.2-0.6-0.1
Change in fecal boli incidents, locomotor task0.10.10.20.40.30.30.20.10.30.30.30.50.3
Time >=10cm from walls, locomotor time 10.20.20.4-0.5-0.2-0.5-0.1-0.6-0.4-0.5-0.5-0.6-0.4
Bouts of movement, locomotor time 10.40.51.4-1.0-0.4-0.6-0.1-0.4-0.6-0.6-0.6-1.2-0.7
Total resting periods, locomotor time 10.50.51.3-1.0-0.5-0.7-0.2-0.5-0.7-0.7-0.7-1.2-0.7
Rest time, locomotor task time 11.21.41.91.11.21.21.21.41.21.21.20.41.1
Distance moved, locomotor task time 12.12.33.2-1.6-1.6-1.5-1.6-1.8-1.5-1.5-1.5-1.0-1.4
Vertical activity count, locomotor time 10.20.20.6-0.1-0.4-0.2-0.8-0.5-0.2-0.2-0.20.7-0.0
Time >=10cm from walls, locomotor time 20.10.10.4-0.1-0.3-0.2-0.7-0.0-0.1-0.2-0.20.60.0
Bouts of movement, locomotor time 22.83.03.71.61.71.91.41.91.81.91.91.21.8
Total resting periods, locomotor time 22.82.93.51.61.81.91.51.81.81.91.91.11.8
Rest time, locomotor task time 21.31.51.91.41.21.31.11.21.31.31.30.81.2
Distance moved, locomotor task time 22.52.93.6-1.8-1.8-1.7-1.9-1.8-1.7-1.7-1.7-1.1-1.6
Vertical activity count, locomotor time 20.60.62.1-0.6-1.0-0.6-1.4-0.8-0.7-0.6-0.60.3-0.5
Weight adjusted by age0.10.10.10.30.30.20.30.20.20.20.20.10.2
Seeking ratio, delayed vs. immediate footshock0.50.60.90.90.80.70.80.80.70.70.70.80.7
Locomotion in novel chamber6.47.98.73.02.72.92.33.02.92.92.92.43.0
Locomotion in novel chamber post-restriction0.30.40.90.50.80.61.00.50.60.60.60.40.6
Progressive ratio0.50.60.80.80.70.70.60.70.80.70.70.90.8
Food seeking constrained by brief footshock0.50.61.90.60.30.7-0.20.80.70.70.71.40.9
Seeking ratio, punishment vs. effort0.50.61.7-0.6-1.0-0.7-1.3-0.6-0.7-0.7-0.7-0.2-0.5
Run reversals in cocaine runway, females1.11.11.4-0.9-1.0-1.2-0.8-1.0-1.0-1.2-1.2-1.1-1.1
Run reversals in cocaine runway, males0.30.31.00.30.30.50.10.70.50.50.51.00.6
Latency to leave start box in cocaine runway0.30.30.5-0.4-0.6-0.6-0.5-0.7-0.5-0.6-0.6-0.6-0.6
Latency to leave start box in cocaine runway, F0.20.20.3-0.5-0.4-0.5-0.3-0.5-0.4-0.5-0.5-0.6-0.6
Latency to leave start box in cocaine runway, M0.30.30.5-0.2-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.5-0.5
Cd content in liver2.42.73.31.81.71.61.71.81.71.61.61.21.5
Co content in liver0.70.81.00.80.80.90.71.00.80.90.91.00.9
Cu content in liver0.20.20.7-0.2-0.2-0.40.2-0.5-0.4-0.4-0.4-0.8-0.5
Fe content in liver0.10.10.1-0.4-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.2-0.3
K content in liver0.00.00.10.10.20.20.20.00.20.20.20.20.2
Mg content in liver0.10.10.30.20.40.30.50.30.30.30.30.20.3
Mn content in liver1.31.52.8-1.1-1.4-1.2-1.7-1.3-1.2-1.2-1.2-0.7-1.1
Na content in liver0.00.00.1-0.1-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.3-0.2
Rb content in liver0.60.70.90.60.90.90.80.80.80.90.90.90.9
Se content in liver0.80.91.81.01.10.91.31.00.90.90.90.40.8
Sr content in liver1.21.11.71.01.11.01.01.31.01.01.01.11.0
Zn content in liver1.01.11.41.11.21.01.21.11.11.01.00.81.0